Professor John O'Leary
Professor Consultant, Histopathology
Professor Consultant, Molecular Medicine Ireland
Publications and Further Research Outputs
Peer-Reviewed Publications
Ffrench B, Kashdan E, Huang Y, Spillane CD, Cocchiglia S, Charmsaz S, Varešlija D, O'Brien C, Scholz D, Martin C, Gallagher M, Brooks DA, Brooks RD, Selemidis S, Gleeson N, AbuSaadeh F, O'Riain C, Kamran W, Flavin R, Young L, O'Toole SA, O'Leary JJ., CTC-5: A novel digital pathology approach to characterise circulating tumour cell biodiversity., Heliyon, 9, (1), 2023, pe13044
Bates M, Mohamed BM, Ward MP, Kelly TE, O'Connor R, Malone V, Brooks R, Brooks D, Selemidis S, Martin C, O'Toole S, O'Leary JJ., Circulating tumour cells: The Good, the Bad and the Ugly., Biochim Biophys Acta Rev Cancer, 1878, (2), 2023, p188863
O'Donovan B., Mooney T., Rimmer B., Fitzpatrick P., Flannelly G., Doherty L., Russell N., Martin C.M., O'Leary J.J., Sharp L., O'Connor M., Trust and cancer screening: Effects of a screening controversy on women's perceptions of cervical cancer screening, Preventive Medicine Reports, 25, 2022
Martini C, Logan JM, Sorvina A, Gordon C, Beck AR, S-Y Ung B, Caruso MC, Moore C, Hocking A, Johnson IRD, Li KL, Karageorgos L, Hopkins AM, Esterman AJ, Huzzell C, Brooks RD, Lazniewska J, Hickey SM, Bader C, Parkinson-Lawrence E, Weigert R, Sorich MJ, Tewari P, Martin C, O'Toole S, Bates M, Ward M, Mohammed B, Keegan H, Watson W, Prendergast S, Heffernan S, NiMhaolcatha S, O'Connor R, Malone V, Carter M, Ryan K, Brady N, Clarke A, Sokol F, Prabhakaran S, Stahl J, Klebe S, Samaratunga H, Delahunt B, Selemidis S, Moretti KL, Butler LM, O'Leary JJ, Brooks DA., Aberrant protein expression of Appl1, Sortilin and Syndecan-1 during the biological progression of prostate cancer., Pathology, 2022, pS0031-3025(22)00226-4
O'Donovan B., Mooney T., Rimmer B., Fitzpatrick P., Flannelly G., Doherty L., Russell N., Martin C.M., O'Leary J.J., Sharp L., O'Connor M., Corrigendum to "Trust and cancer screening: Effects of a screening controversy on women's perceptions of cervical cancer screening" [Prev. Med. Rep. 25 (2022) 101684] (Preventive Medicine Reports (2022) 25, (S2211335521003752), (10.1016/j.pmedr.2021.101684)), Preventive Medicine Reports, 27, 2022
Lazniewska J., Bader C., Hickey S.M., Selemidis S., O'Leary J., Simpson P.V., Stagni S., Plush S.E., Massi M., Brooks D., Rhenium ( I ) conjugates as tools for tracking cholesterol in cells, Metallomics, 14, (8), 2022
O'Toole SA, Huang Y, Norris L, Power Foley M, Shireen R, McDonald S, Kamran W, Ibrahim N, Ward M, Thompson C, Murphy C, D'Arcy T, Farah N, Heron E, O'Leary JJ, Abu Saadeh F, Gleeson N., HE4 and CA125 as preoperative risk stratifiers for lymph node metastasis in endometrioid carcinoma of the endometrium: A retrospective study in a cohort with histological proof of lymph node status., Gynecologic oncology, 2021
Tewari P, Kashdan E, Walsh C, Martin CM, Parnell AC, O'Leary JJ., Estimating the conditional probability of developing human papilloma virus related oropharyngeal cancer by combining machine learning and inverse Bayesian modelling., PLoS computational biology, 17, (8), 2021, pe1009289
O'Donovan B, Mooney T, Rimmer B, Fitzpatrick P, Flannelly G, Doherty L, Martin C, O'Leary J, O'Connor M, Sharp L., Advancing understanding of influences on cervical screening (non)-participation among younger and older women: A qualitative study using the theoretical domains framework and the COM-B model., Health expectations : an international journal of public participation in health care and health policy, 2021
MacDonagh L, Gallagher MF, Ffrench B, Gasch C, Gray SG, Reidy M, Nicholson S, Leonard N, Ryan R, Young V, O'Leary JJ, Cuffe S, Finn SP, O'Byrne KJ, Barr MP., MicroRNA expression profiling and biomarker validation in treatment-naïve and drug resistant non-small cell lung cancer., Translational lung cancer research, 10, (4), 2021, p1773-1791
Spillane CD, Cooke NM, Ward MP, Kenny D, Blackshields G, Kelly T, Bates M, Huang Y, Martin C, Skehan S, Canney A, Gallagher M, Smyth P, Brady N, Clarke A, Mohamed B, Norris L, Brooks DA, Brooks RD, Heatlie JK, Selemidis S, Hanniffy S, Dixon E, Sheils O, O'Toole SA, O'Leary JJ., The induction of a mesenchymal phenotype by platelet cloaking of cancer cells is a universal phenomenon., Translational oncology, 14, (12), 2021, p101229
Ward, Mark P., Saadeh, Feras Abu, O'Toole, Sharon A., O'Leary, John J., Gleeson, Noreen, Norris, Lucy A., Procoagulant activity in high grade serous ovarian cancer patients following neoadjuvant chemotherapy-The role of the activated protein C pathway, Thrombosis Research, 200, 2021, p91 - 98
Jose, B. and Vijayaraghavan, R.K. and Kent, L. and O'Toole, S. and O'Leary, J. and Forster, R.J., Tunable metallic nanostructures using 3D printed nanosphere templates, Electrochemistry Communications, 98, 2019, p106-109
Traynor D, Kearney P, Ramos I, Martin CM, O'Leary JJ, Lyng FM., A study of hormonal effects in cervical smear samples using Raman spectroscopy., Journal of biophotonics, 2018, pe201700240-
Thompson C, Kamran W, Dockrell L, Khalid S, Kumari M, Ibrahim N, OʼLeary J, Norris L, Petzold M, OʼToole S, Gleeson N, The Clearance of Serum Human Epididymis Protein 4 Following Primary Cytoreductive Surgery for Ovarian Carcinoma, International Journal of Gynaecological Cancer, 28, (6), 2018, p1066 - 1072
O'Connor M, O'Brien K, Waller J, Gallagher P, D'Arcy T, Flannelly G, Martin CM, McRae J, Prendiville W, Ruttle C, White C, Pilkington L, O'Leary JJ, Sharp L, Irish Cervical Screening Research Consortium (CERVIVA)., Physical after-effects of colposcopy and related procedures, and their inter-relationship with psychological distress: a longitudinal survey., BJOG : an international journal of obstetrics and gynaecology, 124, (9), 2017, p1402-1410
Sheill, Gráinne and Brady, Lauren and Guinan, Emer and Hayes, Brian and Casey, Orla and Greene, John and Vlajnic, Tatjana and Cahill, Fidelma and Van Hemelrijck, Mieke and Peat, Nicola and Rudman, Sarah and Hussey, Juliette and Cunningham, Moya and Grogan, Liam and Lynch, Thomas and Manecksha, Rustom P and McCaffrey, John and Mucci, Lorelei and Sheils, Orla and O'Leary, John and O'Donnell, Dearbhaile M and McDermott, Ray and Finn, Stephen, The ExPeCT (Examining Exercise, Prostate Cancer and Circulating Tumour Cells) trial: study protocol for a randomised controlled trial, Trials, 18, (1), 2017, p456
Lynam-Lennon N, Heavey S, Sommerville G, Bibby BA, Ffrench B, Quinn J, Gasch C, O'Leary JJ, Gallagher MF, Reynolds JV, Maher SG, MicroRNA-17 is downregulated in esophageal adenocarcinoma cancer stem-like cells and promotes a radioresistant phenotype, Oncotarget, 8, (7), 2017, p11400 - 11413
To, E.E. and Vlahos, R. and Luong, R. and Halls, M.L. and Reading, P.C. and King, P.T. and Chan, C. and Drummond, G.R. and Sobey, C.G. and Broughton, B.R.S. and Starkey, M.R. and Van Der Sluis, R. and Lewin, S.R. and Bozinovski, S. and O'Neill, L.A.J. and Quach, T. and Porter, C.J.H. and Brooks, D.A. and O'Leary, J.J. and Selemidis, S., Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy, Nature Communications, 8, (1), 2017
Sulaiman, G, Cooke A, Ffrench B, Gasch C, Abdullai OA, O'Connor K, Elbaruni S, Blacksheilds G, Spillane C, Keegan H, McEneaney V, Knittel R, Rogers A, Jeffery IB, Doyle B, Bates M, d'Adhemar C, Lee M, Campbell EL, Moynagh P, Higgins DG, O'Toole S, O'Neill L, O'Leary JJ and Gallagher MF. , MyD88 is an essential component of retinoic acid induced differentiation in human pluripotent embryonal carcinoma cells. , Cell Death & Differentiation , 24, (11), 2017, p1975 - 1986
Woods RSR, Keegan H, White C, Tewari P, Toner M, Kennedy S, O'Regan EM, Martin CM, Timon CVI, O'Leary JJ., Cytokeratin 7 in Oropharyngeal Squamous Cell Carcinoma: A Junctional Biomarker for Human Papillomavirus-Related Tumors., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 26, (5), 2017, p702-710
Arts, Florence A and Keogh, Lisa and Smyth, Paul and O'Toole, Sharon and Ta, Robert and Gleeson, Noreen and O'Leary, John J and Flavin, Richard and Sheils, Orla, miR-223 potentially targets SWI/SNF complex protein SMARCD1 in atypical proliferative serous tumor and high-grade ovarian serous carcinoma, Human pathology, 70, 2017, p98 - 104
Kearney P, Traynor D, Bonnier F, Lyng FM, O'Leary JJ, Martin CM., Raman spectral signatures of cervical exfoliated cells from liquid-based cytology samples., Journal of biomedical optics, 22, (10), 2017, p1-10
Staunton Lisa, Tonry Claire, Lis Rosina, Espina Virginia, Liotta Lance, Inzitari Rosanna, Bowden Michaela, Fabre Aurelie, O'Leary John, Finn Stephen P, Loda Massimo, Pennington Stephen R, Pathology-Driven Comprehensive Proteomic Profiling of the Prostate Cancer Tumor Microenvironment , Molecular cancer research : MCR , 15 , (3 ), 2017, p281 - 293
Gasch, C. and Ffrench, B. and O'Leary, J.J. and Gallagher, M.F., Catching moving targets: Cancer stem cell hierarchies, therapy-resistance & considerations for clinical intervention, Molecular Cancer, 16, (1), 2017, p43-
O'Connor M, Gallagher P, Waller J, Martin CM, O'Leary JJ, Sharp L, Irish Cervical Screening Research Consortium (CERVIVA)., Adverse psychological outcomes following colposcopy and related procedures: a systematic review., BJOG : an international journal of obstetrics and gynaecology, 123, (1), 2016, p24-38
O'Connor M, O'Leary E, Waller J, Gallagher P, D'Arcy T, Flannelly G, Martin C.M, McRae J, Prendiville W, Ruttle C, White C, Pilkington L, O'Leary J.J, Sharp L, Trends in, and predictors of, anxiety and specific worries following colposcopy: A 12-month longitudinal study, Psycho-Oncology, 25, (5), 2016, p597 - 604
Aherne, S.T., Smyth, P., Freeley, M., Smith, L., Spillane, C., O'Leary, J., Sheils, O., Altered expression of MIR-222 and MIR-25 influences diverse gene expression changes in transformed normal and anaplastic thyroid cells, and impacts on MEK and TRAIL protein expression, International Journal of Molecular Medicine, 38, (2), 2016, p433-445
Emma R Dorris, Gordon Blackshields, Gary Sommerville, Mohsen Alhashemi, Andrew Dias, Victoria McEneaney, Paul Smyth, John J O'Leary, Orla Sheils, Pluripotency markers are differentially induced by MEK inhibition in thyroid and melanoma BRAFV600E cell lines, Cancer biology & therapy, 17, (5), 2016, p526 - 542
Staunton, L., Tonry, C., Lis, R., Finn, S., O'Leary, J., Loda, M., Bowden, M., Pennington, S.R., Profiling the tumor microenvironment proteome in prostate cancer using laser capture microdissection coupled to LC-MS-A technical report, EuPA Open Proteomics, 10, 2016, p19-23
Cooke, N.M., Spillane, C.D., Sheils, O., O'Leary, J., Kenny, D., Aspirin and P2Y
Langhe R, Norris L, Saadeh FA, Blackshields G, Varley R, Harrison A, Gleeson N, Spillane C, Martin C, O'Donnell DM, D'Arcy T, O'Leary J, O'Toole S, A novel serum microRNA panel to discriminate benign from malignant ovarian disease, Cancer Letters, 356, ((2ptB)), 2015, p628-636-
Holl K, Nowakowski A.M, Powell N, McCluggage W.G, Pirog E.C, Collas De Souza S, Tjalma W.A, Rosenlund M, Fiander A, Castro Sánchez M, Damaskou V, Joura E.A, Kirschner B, Koiss R, O'Leary J, Quint W, Reich O, Torné A, Wells M, Rob L, Kolomiets L, Molijn A, Savicheva A, Shipitsyna E, Rosillon D, Jenkins D, Human papillomavirus prevalence and type-distribution in cervical glandular neoplasias: Results from a European multinational epidemiological study, International Journal of Cancer, 137, (12), 2015, p2858 - 2868
O'Connor M, Costello L, Murphy J, Prendiville W, Martin CM, O'Leary JJ, Sharp L, Influences on human papillomavirus (HPV)-related information needs among women having HPV tests for follow-up of abnormal cervical cytology., The journal of family planning and reproductive health care / Faculty of Family Planning & Reproductive Health Care, Royal College of Obstetricians & Gynaecologists, 41, (2), 2015, p134-141
Busschots,Steven S., O'Toole,Sharon A. S.A., O'Leary,John James J.J., Stordal,Britta K. B.K., Non-invasive and non-destructive measurements of confluence in cultured adherent cell lines, MethodsX, 2, 2015, p8-13
O'Connor M, Waller J, Gallagher P, Martin C.M, O'Leary J.J, D'Arcy , Prendiville W, Flannelly G, Sharp L, Understanding Women's Differing Experiences of Distress after Colposcopy: A Qualitative Interview Study, Women's Health Issues, 25, (5), 2015, p528 - 534
Langhe R, Norris L, Saadeh FA, Blackshields G, Varley R, Harrison A, Gleeson N, Spillane C, Martin C, O'Donnell DM, D'Arcy T, O'Leary J, O'Toole S, A novel serum microRNA panel to discriminate benign from malignant ovarian disease., Cancer letters, 356, (2 Pt B), 2015, p628-36
Johnson IR, Parkinson-Lawrence EJ, Keegan H, Spillane CD, Barry-O'Crowley J, Watson WR, Selemidis S, Butler LM, O'Leary JJ, Brooks DA, Endosomal gene expression: a new indicator for prostate cancer patient prognosis?, Oncotarget, 6, (35), 2015, p37919-29
Gallagher, M.F., Salley, Y., Spillane, C.D., Ffrench, B., Baruni, S.E., Blacksheilds, G., Smyth, P., Martin, C., Sheils, O., Watson, W., O'Leary, J.J., Enhanced regulation of cell cycle and suppression of osteoblast differentiation molecular signatures by prostate cancer stem-like holoclones, Journal of Clinical Pathology, 68, (9), 2015, p692-702
McEvoy, L.M., O'Toole, S.A., Spillane, C.D., Martin, C.M., Gallagher, M.F., Stordal, B., Blackshields, G., Sheils, O., O'Leary, J.J., Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer, BMC Cancer, 15, (1), 2015, p547-
Glynn M, Kirby D, Nwankire C, Kinahan D, Spillane C, Shiels O, O'Leary J, Ducrée J, Staging the clinical status from blood of cancer patients by chip-based cell enumeration following targetted removal of normal cells, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, 2014, 2014, pp461 - 463
d'Adhemar CJ, Spillane CD, Gallagher MF, Bates M, Costello KM, Barry-O'Crowley J, Haley K, Kernan N, Murphy C, Smyth PC, O'Byrne K, Pennington S, Cooke AA, Ffrench B, Martin CM, O'Donnell D, Hennessy B, Stordal B, Finn S, McCann A, Gleeson N, D'Arcy T, Flood B, O'Neill LA, Sheils O, O'Toole S, O'Leary JJ., The MyD88+ Phenotype Is an Adverse Prognostic Factor in Epithelial Ovarian Cancer., PLoS One. , 9, (6), 2014, pe100816-
O'Connor, M. Murphy, J. Martin, C. O'Leary, J. Sharp, L., Motivators for women to attend cervical screening: The influential role of GPs, Family Practice, 31, (4), 2014, p475-482
McRae, J. Martin, C. O'Leary, J. Sharp, L., "If you can't treat HPV, why test for it?" Women's attitudes to the changing face of cervical cancer prevention: A focus group study, BMC Women's Health, 14, (1), 2014, p64-
O'Brien CP, Taylor SE, O'Leary JJ, Finn SP, Molecular testing in oncology: Problems, pitfalls and progress., Lung cancer (Amsterdam, Netherlands), 2014
O'Brien CP, Langabeer SE, O'Byrne KJ, O'Leary JJ, Finn SP, Predictive values for molecular diagnostics: converting unknown unknowns to known unknowns., Molecular diagnosis & therapy, 18, (1), 2014, p1-4
Rashid N, Nawaz H, Poon KW, Bonnier F, Bakhiet S, Martin C, O'Leary JJ, Byrne HJ, Lyng FM, Raman microspectroscopy for the early detection of pre-malignant changes in cervical tissue., Experimental and molecular pathology, 97, (3), 2014, p554-64
Lawlor, D. Martin, P. Busschots, S. Thery, J. O'Leary, J.J. Hennessy, B.T. Stordal, B., PARP inhibitors as p-glyoprotein substrates, Journal of Pharmaceutical Sciences, 103, (6), 2014, p1913 - 1920
Keegan Helen, Pilkington Loretto, McInerney Jamie, Jeney Csaba, Benczik Márta, Cleary Sinead, von Bunau Gunther, Turner Michael, D'Arcy Tom, O' Toole Sharon, Borbála Pal-Szenthe, Borbála Kaltenecker, Johanna Mózes, Anettc Kovács, Agnes Solt, Bolger Noel, O'Leary John, Martin Cara., Human papillomavirus detection and genotyping, by HC2, Full-Spectrum HPV and Molecular Beacon Real-Time HPV assay in an Irish colposcopy clinic, Journal of Virological Methods, 2014
Doherty B, Lawlor D, Gillet JP, Gottesman M, O'Leary JJ, Stordal B, Collateral Sensitivity to Cisplatin in KB-8-5-11 Drug-resistant Cancer Cells., Anticancer research, 34, (1), 2014, p503-7
Vencken SF, Sethupathy P, Blackshields G, Spillane C, Elbaruni S, Sheils O, Gallagher MF, O'Leary JJ, An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines., BMC genomics, 15, 2014, p711
Sadlier C, Rowley D, Morley D, Surah S, O'Dea S, Delamere S, O'Leary J, Smyth P, Clarke S, Sheils O, Bergin C, Prevalence of human papillomavirus in men who have sex with men in the era of an effective vaccine; a call to act., HIV medicine, 15, (8), 2014, p499-504
Kelly LA, Seidlova-Wuttke D, Wuttke W, O'Leary JJ, Norris LA, Estrogen receptor alpha augments changes in hemostatic gene expression in HepG2 cells treated with estradiol and phytoestrogens. , Phytomedicine , 21, (2), 2014, p155 - 158
O'Connor M, Costello L, Murphy J, Prendiville W, Martin C.M, O'Leary J.J, Sharp L, 'I don't care whether it's HPV or ABC, i just want to know if i have cancer.' Factors influencing women's emotional responses to undergoing human papillomavirus testing in routine management in cervical screening: A qualitative study, BJOG: An International Journal of Obstetrics and Gynaecology, 121, (11), 2014, p1421 - 1429
Ffrench B, Gasch C, O'Leary JJ, Gallagher MF, Developing ovarian cancer stem cell models: laying the pipeline from discovery to clinical intervention., Molecular cancer, 13, 2014, p262
Loy A, McInerney J, Pilkington L, Keegan H, Delamere S, Martin CM, Sheils O, O'Leary JJ, Mulcahy F., Human papillomavirus DNA and mRNA prevalence and association with cervical cytological abnormalities in the Irish HIV population., International Journal of Sexually Transmitted Diseases and AIDS, 2014
d'Adhemar CJ, Spillane CD, Gallagher MF, Bates M, Costello KM, Barry-O'Crowley J, Haley K, Kernan N, Murphy C, Smyth PC, O'Byrne K, Pennington S, Cooke AA, Ffrench B, Martin CM, O'Donnell D, Hennessy B, Stordal B, Finn S, McCann A, Gleeson N, D'Arcy T, Flood B, O'Neill LA, Sheils O, O'Toole S, O'Leary JJ, The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer., PloS one, 9, (6), 2014, pe100816
Keegan H, Pilkington L, McInerney J, Jeney C, Benczik M, Cleary S, von Bunau G, Turner M, D'Arcy T, O' Toole S, Pal-Szenthe B, Kaltenecker B, Mózes J, Kovács A, Solt A, Bolger N, O'Leary J, Martin C, Human papillomavirus detection and genotyping, by HC2, full-spectrum HPV and molecular beacon real-time HPV assay in an Irish colposcopy clinic., Journal of virological methods, 201, 2014, p93-100
Bonnier,F, Traynor, D, Kearney, P, Clarke,C, Peter Knief, P Martin, C, O'Leary,J, Byrne HJ and Lyng, F, Processing ThinPrep Cervical Cytological Samples for Raman Spectroscopic Analysis., Analytical Methods, 6, (19), 2014, p7831 - 7841
Busschots S, O'Toole S, O'Leary JJ, Stordal B. , Carboplatin and taxol resistance develops more rapidly in functional BRCA1 compared to dysfunctional BRCA1 ovarian cancer cells, Experimental Cell Research, 2014, p1 - 14
White C, Keegan H, Pilkington L, Ruttle C, Kerr P, Sharp L, O'Toole S, Turner M, Prendiville W, D'Arcy T, Fitzpatrick M, Lenehan P, Flannelly G, O'Leary JJ, Martin CM, Evaluation of the clinical performance of the cobas 4800 HPV test in patients referred for colposcopy., Journal of clinical microbiology, 51, (10), 2013, p3415-7
Laios A, Mohamed BM, Kelly L, Flavin R, Finn S, McEvoy L, Gallagher M, Martin C, Sheils O, Ring M, Davies A, Lawson M, Gleeson N, D'Arcy T, d'Adhemar C, Norris L, Langhe R, Saadeh FA, O'Leary JJ, O'Toole SA, Pre-Treatment of Platinum Resistant Ovarian Cancer Cells with an MMP-9/MMP-2 Inhibitor Prior to Cisplatin Enhances Cytotoxicity as Determined by High Content Screening., International journal of molecular sciences, 14, (1), 2013, p2085-103
Abu Saadeh, Norris L, O'Toole S, Mohamed BM, Langhe R, O'Leary J, Gleeson N, Tumour expresion of tissue factor and tissue factor pathway inhibitor in ovarian cancer- relationship with venous thrombosis risk., Thrombosis Research, 132, 2013, p627 - 634
Tjalma WA, Fiander A, Reich O, Powell N, Nowakowski AM, Kirschner B, Koiss R, O'Leary J, Joura EA, Rosenlund M, Colau B, Schledermann D, Kukk K, Damaskou V, Repanti M, Vladareanu R, Kolomiets L, Savicheva A, Shipitsyna E, Ordi J, Molijn A, Quint W, Raillard A, Rosillon D, De Souza SC, Jenkins D, Holl K, Differences in human papillomavirus type distribution in high-grade cervical intraepithelial neoplasia and invasive cervical cancer in Europe., International journal of cancer. Journal international du cancer, 132, (4), 2013, p854-67
Brosnan JF, Sheppard BL, Kelly LA, O'Leary JJ, Norris LA, Norethisterone acetate alters coagulation gene expression in vitro in human cell culture., Thrombosis research, 131, (1), 2013, p72 - 77
Barr MP, Gray SG, Hoffmann AC, Hilger RA, Thomale J, O'Flaherty JD, Fennell DA, Richard D, O'Leary JJ, O'Byrne KJ., Generation and characterisation of Cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature., PloS one, 8, (1), 2013, pe54193
Abu Saadeh F, Norris L, O'Toole S, Langhe R, O'Leary JJ, Gleeson N., Does tissue factor and tissue factor pathway inhibitor over-expression play a role in the development of venous thromboembolism in ovarian cancer patients?, Thrombosis Research, 6th International Conference on Thrombosis & Hemostasis Issues in Cancer, Bergamo Italy, April 2012, edited by A Falanga, B. Brenner, F, Rickles , 129, ((Suppl 1)), Elsevier, 2012, pp170-
Murphy MA, O'Connell DJ, O'Kane SL, O'Brien JK, O'Toole S, Martin C, Sheils O, O'Leary JJ, Cahill DJ, Epitope presentation is an important determinant of the utility of antigens identified from protein arrays in the development of autoantibody diagnostic assays, Journal of Proteomics, 75, (15), 2012, p4668 - 4675
Abu Saadeh F, Norris L, O'Toole S, Langhe R, Gleeson N., Procoagulant activity in patients with gynecological malignancies and the effect of neoadjuvant chemotherapy , Thrombosis Research, 6th International Conference on Thrombosis & Hemostasis Issues in Cancer, Bergamo Italy, April 2012, edited by A Falanga, B. Brenner, F, Rickles , 129, (Suppl 1), Elsevier, 2012
McSherry LA, Dombrowski SU, Francis JJ, Murphy J, Martin CM, O'Leary JJ, Sharp L, Group A, 'It's a can of worms': understanding primary care practitioners' behaviours in relation to HPV using the theoretical domains framework., Implementation science : IS, 7, (1), 2012, p73
O'Flaherty JD, Gray S, Richard D, Fennell D, O'Leary JJ, Blackhall FH, O'Byrne KJ, Circulating tumour cells, their role in metastasis and their clinical utility in lung cancer., Lung cancer (Amsterdam, Netherlands), 76, (1), 2012, p19-25
Logan C, Habington A, Lennon G, Grogan J, Byrne M, O'Leary J, O'Sullivan N, Genetic relatedness of Pseudomonas aeruginosa isolates among a paediatric cystic fibrosis patient cohort in Ireland., Journal of medical microbiology, 61, (Pt 1), 2012, p64-70
Flavin R, Finn SP, Choueiri TK, Ingoldsby H, Ring M, Barrett C, Rogers M, Smyth P, O'Regan E, Gaffney E, O'Leary JJ, Loda M, Signoretti S, Sheils O, RET protein expression in papillary renal cell carcinoma., Urologic oncology, 30, (6), 2012, p900-5
Abu Saadeh. F, Norris. L, O' Toole. S, Langhe. R, O' Leary. J, Gleeson. N. , Why is venous thromboembolism is a common complication of ovarian cancer? , International Journal of Gynecological Cancer , 14th Biennial Meeting of the International Gynecological Cancer Society. , Vancouver, Canada, October 2012, 22, (Suppl 3), 2012, ppE247-
Gulliksen A, Keegan H, Martin C, O'Leary J, Solli LA, Falang IM, Grønn P, Karlgård A, Mielnik MM, Johansen IR, Tofteberg TR, Baier T, Gransee R, Drese K, Hansen-Hagge T, Riegger L, Koltay P, Zengerle R, Karlsen F, Ausen D, Furuberg L, Towards a "Sample-In, Answer-Out" Point-of-Care Platform for Nucleic Acid Extraction and Amplification: Using an HPV E6/E7 mRNA Model System., Journal of oncology, 2012, 2012, p905024
Scharfe-Nugent A, Corr SC, Carpenter SB, Keogh L, Doyle B, Martin C, Fitzgerald KA, Daly S, O'Leary JJ, O'Neill LA, TLR9 provokes inflammation in response to fetal DNA: mechanism for fetal loss in preterm birth and preeclampsia., Journal of immunology (Baltimore, Md. : 1950), 188, (11), 2012
O'Flaherty JD, Barr M, Fennell D, Richard D, Reynolds J, O'Leary J, O'Byrne K, The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy., Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 7, (12), 2012, p1880-90
Furlong F, Fitzpatrick P, O'Toole S, Phelan S, McGrogan B, Maguire A, O'Grady A, Gallagher M, Prencipe M, McGoldrick A, McGettigan P, Brennan D, Sheils O, Martin C, W Kay E, O'Leary J, McCann A, Low MAD2 expression levels associate with reduced progression-free survival in patients with high-grade serous epithelial ovarian cancer., The Journal of pathology, 226, (5), 2012, p746-55
Abu Saadeh. F, Norris. L, O' Toole. S, Langhe. R, Gleeson. N, Endogenous thrombin potential as a marker for venous thrombosis in ovarian cancer., International Journal of Gynecological Cancer , 14th Biennial Meeting of the International Gynecological Cancer Society., Vancouver, Canada, October 2012, 22, (Suppl 3), 2012, ppE248-
Dorris ER, Smyth P, O'Leary JJ, Sheils O, MIR141 Expression Differentiates Hashimoto Thyroiditis from PTC and Benign Thyrocytes in Irish Archival Thyroid Tissues., Frontiers in endocrinology, 3, 2012, p102
Gallagher MF, Heffron CC, Laios A, O'Toole SA, Ffrench B, Smyth PC, Flavin RJ, Elbaruni SA, Spillane CD, Martin CM, Sheils OM, O'Leary JJ, Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples., Journal of ovarian research, 5, (1), 2012, p2
Murphy MA, O'Leary JJ, Cahill DJ, Assessment of the humoral immune response to cancer., Journal of proteomics, 75, (15), 2012, p4573-9
Martin CM, O'Leary JJ, Histology of cervical intraepithelial neoplasia and the role of biomarkers., Best practice & research. Clinical obstetrics & gynaecology, 25, (5), 2011, p605-15
Oon SF, Watson RW, O'Leary JJ, Fitzpatrick JM, Epstein criteria for insignificant prostate cancer., BJU international, 2011
Astbury K, McEvoy L, Brian H, Spillane C, Sheils O, Martin C, O'Leary JJ, MYBL2 (B-MYB) in cervical cancer: putative biomarker., International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 21, (2), 2011, p206-12
O'Hurley G, Perry AS, O'Grady A, Loftus B, Smyth P, O'Leary JJ, Sheils O, Fitzpatrick JM, Hewitt SM, Lawler M, Kay EW, The role of secreted frizzled-related protein 2 expression in prostate cancer., Histopathology, 59, (6), 2011, p1240-1248
Ostrowska KM, Garcia A, Meade AD, Malkin A, Okewumi I, O'Leary JJ, Martin C, Byrne HJ, Lyng FM, Correlation of p16(INK4A) expression and HPV copy number with cellular FTIR spectroscopic signatures of cervical cancer cells., The Analyst, 136, (7), 2011, p1365-73
Egan K, Crowley D, Smyth P, O'Toole S, Spillane C, Martin C, Gallagher M, Canney A, Norris L, Conlon N, McEvoy L, Ffrench B, Stordal B, Keegan H, Finn S, McEneaney V, Laios A, Ducrée J, Dunne E, Smith L, Berndt M, Sheils O, Kenny D, O'Leary J, Platelet adhesion and degranulation induce pro-survival and pro-angiogenic signalling in ovarian cancer cells., PloS one, 6, (10), 2011, pe26125
Egan K, Crowley D, Smyth P, O'Toole S, Spillane C, Martin C, Gallagher M, Canney A, Norris L, Conlon N, McEvoy L, Ffrench B, Stordal B, Keegan H, Finn S, McEneaney V, Laios A, Ducrée J, Dunne E, Smith L, Berndt M, Sheils O, Kenny D, O'Leary J, Platelet Adhesion and Degranulation Induce Pro-Survival and Pro-Angiogenic Signalling in Ovarian Cancer Cells, PLoS ONE, 6, (10, e26125), 2011
Yusof A, Keegan H, Spillane CD, Sheils OM, Martin CM, O'Leary JJ, Zengerle R, Koltay P, Inkjet-like printing of single-cells., Lab on a chip, 11, (14), 2011, p2447-54
Grogan JA, Logan C, O'Leary J, Rush R, O'Sullivan N, Real-time PCR-based detection of Bordetella pertussis and Bordetella parapertussis in an Irish paediatric population., Journal of medical microbiology, 60, (Pt 6), 2011, p722-9
Cantwell-Dorris ER, O'Leary JJ, Sheils OM, BRAFV600E: implications for carcinogenesis and molecular therapy., Molecular cancer therapeutics, 10, (3), 2011, p385-94
Ostrowska KM, Malkin A, Meade A, O'Leary J, Martin C, Spillane C, Byrne HJ, Lyng FM., Investigation of the influence of high-risk human papillomavirus on the biochemical composition of cervical cancer cells using vibrational spectroscopy., Analyst., (Oct 21), 2010
Sheedy FJ, Palsson-McDermott E, Hennessy EJ, Martin C, O'Leary JJ, Ruan Q, Johnson DS, Chen Y, O'Neill LA., Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21, Nature Immunology, 11, (2), 2010, p141-147
Mocanu E, Shattock R, Barton D, Rogers M, Conroy R, Sheils O, Collins C, Martin C, Harrison R, O'Leary J, All azoospermic males should be screened for cystic fibrosis mutations before intracytoplasmic sperm injection., Fertility and sterility, 2010
Kelly JG, Cheung KT, Martin C, O'Leary JJ, Prendiville W, Martin-Hirsch PL, Martin FL, A spectral phenotype of oncogenic human papillomavirus-infected exfoliative cervical cytology distinguishes women based on age., Clinica chimica acta; international journal of clinical chemistry, 411, (15-16), 2010, p1027-1033
O'Hurley G, O'Grady A, Smyth P, Byrne J, O'Leary JJ, Sheils O, Watson RW, Kay EW, Evaluation of Zinc-alpha-2-Glycoprotein and Proteasome Subunit beta-Type 6 Expression in Prostate Cancer Using Tissue Microarray Technology., Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry, 2010
Kelly LA, O'Leary JJ, Seidlova-Wuttke D, Wuttke W, Norris LA, Genistein alters coagulation gene expression in ovariectomised rats treated with phytoestrogens, Thrombosis and Haemostasis, 104, (6), 2010, p1083-1289
Baier T, Hansen-Hagge TE, Gransee R, Crombé A, Schmahl S, Paulus C, Drese KS, Keegan H, Martin C, O'Leary JJ, Furuberg L, Solli L, Grønn P, Falang IM, Karlgård A, Gulliksen A, Karlsen F, Hands-free sample preparation platform for nucleic acid analysis., Lab on a chip, 9, (23), 2009, p3399-405
Flavin, R.J., Smyth, P.C., Laios, A., O'Toole, S.A., Barrett, C., Finn, S.P., Russell, S., (...), O'Leary, J.J. , Potentially important microRNA cluster on chromosome 17p13.1 in primary peritoneal carcinoma, Modern Pathology , 22, (2), 2009, p197-205
Keegan, H., Mc Inerney, J., Pilkington, L., Grønn, P., Silva, I., Karlsen, F., Bolger, N., (...), Martin, C. , Comparison of HPV detection technologies: Hybrid capture 2, PreTect HPV-Proofer and analysis of HPV DNA viral load in HPV16, HPV18 and HPV33 E6/E7 mRNA positive specimens, Journal of Virological Methods , 155, (1), 2009, p61-66
Flavin R, Smyth P, Barrett C, Russell S, Wen H, Wei J, Laios A, O'Toole S, Ring M, Denning K, Li J, Aherne S, Sammarae D, Aziz NA, Alhadi A, Finn SP, Loda M, B S, Sheils O, O'Leary JJ, miR-29b expression is associated with disease-free survival in patients with ovarian serous carcinoma., International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 19, (4), 2009, p641-7
Flavin R, Jackl G, Finn S, Smyth P, Ring M, O'Regan E, Cahill S, Unger K, Denning K, Jinghuan Li Aherne S, Tallini G, Gaffney E, O'Leary JJ, Zitzelsberger H, Sheils O, RET/PTC rearrangement occurring in primary peritoneal carcinoma., International journal of surgical pathology, 17, (3), 2009, p187-97
Gallagher MF, Flavin RJ, Elbaruni SA, McInerney JK, Smyth PC, Salley YM, Vencken SF, O'Toole SA, Laios A, Lee MY, Denning K, Li J, Aherne ST, Lao KQ, Martin CM, Sheils OM, O'Leary JJ, Regulation of microRNA biosynthesis and expression in 2102Ep embryonal carcinoma stem cells is mirrored in ovarian serous adenocarcinoma patients., Journal of ovarian research, 2, 2009, p19
Field JK, Liloglou T, Niaz A, Bryan J, Gosney JR, Giles T, Brambilla C, Brambilla E, Vesin A, Timsit JF, Hainaut P, Martinet Y, Vignaud JM, Thunnissen FB, Prinsen C, Snijders PJ, Smit EF, Sozzi G, Roz L, Risch A, Becker HD, Elborn JS, Magee ND, Montuenga LM, Pajares MJ, Lozano MD, O'Byrne KJ, Harrison DJ, Niklinski J, Cassidy A, EUELC project: a multi-centre, multipurpose study to investigate early stage NSCLC, and to establish a biobank for ongoing collaboration., The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology, 34, (6), 2009, p1477-86
Laios, A., O'Toole, S.A., Flavin, R., Martin, C., Ring, M., Gleeson, N., D'Arcy, T., (...), O' Leary, J.J. , An integrative model for recurrence in ovarian cancer , Molecular Cancer, 7, 2008
Aherne ST, Smyth PC, Flavin RJ, Russell SM, Denning KM, Li JH, Guenther SM, O'Leary JJ, Sheils OM., Geographical mapping of a multifocal thyroid tumour using genetic alteration analysis & miRNA profiling., Molecular Cancer, 7, 2008, particle no, 89
Hornig, M., Briese, T., Buie, T., Bauman, M.L., Lauwers, G., Siemetzki, U., Hummel, K., (...), Lipkin, W.I. , Lack of association between measles virus vaccine and autism with enteropathy: A case-control study , PLoS ONE, 3, (9), 2008, part. no. e3140
Laios, A., O'Toole, S., Flavin, R., Martin, C., Kelly, L., Ring, M., Finn, S.P., (...), O'Leary, J. , Potential role of miR-9 and miR-223 in recurrent ovarian cancer , Molecular Cancer, 7, 2008, part. no. 35
Murphy AJ, Hughes CA, Barrett C, Magee H, Loftus B, O'Leary JJ, Sheils O, Low Level TOP2A Amplification in Prostate Cancer is associated with HER2 Duplication, Androgen Resistance and Decreased Survival, Cancer Research , 67, (6), 2007, p2893 - 2898
Crowley A, Martin C, Fitzpatrick P, Sheils O, O'Herlihy C, O'Leary JJ, Byrne BM, Free fetal DNA is not increased before 20 weeks in intrauterine growth, Prenat Diagn., 27, (2), 2007, p174 - 179
Murphy AJ, Hughes CA, Lannigan G, Sheils O, O'Leary J, Loftus B, Heterogeneous expression of alpha-methylacyl-CoA racemase in prostatic cancer correlates with Gleason score, Histopathology, 50, (2), 2007, p243 - 251
Logan, C., O'Leary, J.J., O'Sullivan, N. , Real-time reverse transcription PCR detection of norovirus, sapovirus and astrovirus as causative agents of acute viral gastroenteritis , Journal of Virological Methods, 146, (1-2), 2007, p36-44
Finn SP, Smyth P, Cahill S, Streck C, O'regan EM, Flavin R, Sherlock J,Howells D, Henfrey R, Cullen M, Toner M, Timon C, O'leary JJ, Sheils OM, Expression microarray analysis of papillary thyroid carcinoma and benign thyroid tissue: emphasis on the follicular variant and potential markers of malignancy, Virchows Arch, 450, (3), 2007, p249 - 260
Martin CM, Kehoe L, Spillane CO, O'Leary JJ., Gene discovery in cervical cancer : towards diagnostic and therapeutic biomarkers., Molecular Diagnosis and Therapy , 11, (5), 2007, p277-90
Heffron, C.C.B.B., Gallagher, M.F., Guenther, S., Sherlock, J., Henfrey, R., Martin, C., Sheils, O., O'Leary, J.J. , Global mRNA analysis to determine a transcriptome profile of cancer stemness in a mouse model , Anticancer Research, 27, (3A), 2007, p1319-1324
O'Toole SA, Sheppard BL, Laios A, O'Leary JJ, McGuinness EP, D'Arcy T,Bonnar J, Potential predictors of chemotherapy response in ovarian cancer--how do we define chemosensitivity?, Gynecol Oncol., 104, (2), 2007, p345 - 351
Furuberg, L., Mielnik, M., Johansen, I.-R., Voitel, J., Gulliksen, A., Solli, L., Karlsen, F., (...), Koltay, P. , The micro active project: Automatic detection of disease-related molecular cell activity , Proceedings of SPIE - The International Society for Optical Engineering, 6589, 2007, part. no. 65891B
Logan C, O'Leary JJ, O'Sullivan N, Real-time reverse transcription-PCR for detection of rotavirus and adenovirus as causative agents of acute viral gastroenteritis in children, J Clin Microbiol., 44, (9), 2006, p3189 - 3195
O'Toole SA, Dunn E, Sheppard BL, Klocker H, Bektic J, Smyth P, Martin C, Sheils O, O'Leary JJ, Genome-wide analysis of deoxyribonucleic acid in endometrial cancer using comparative genomic hybridization microarrays, International Journal of Gynecological Cancer , 16, (2), 2006, p834 - 842
Bolger, N., Heffron, C., Regan, I., Sweeney, M., Kinsella, S., McKeown, M., Creighton, G., (...), O'Leary, J. , Cervical cytology: Implementation and evaluation of a new automated interactive image analysis system , Acta Cytologica, 50 - (5), 2006, p483-491
Bolger N, Heffron C, Regan I, Sweeney M, Kinsella S, McKeown M, Creighton G,Russell J, O'Leary J, Implementation and evaluation of a new automated interactive image analysis system, Acta Cytol., 50, (5), 2006, p483 - 491
Leahy M, Farah N, Bolger N, O'Leary JJ, Turner MJ, Should cervical smears be taken at a postnatal visit?, Irish Medical Journal, 99, (8), 2006, p244 - 245
Martin CM, Astbury K, O'Leary JJ, Molecular profiling of cervical neoplasia, Expert Review of Molecular Diagnostics , 6, (2), 2006, p217 - 229
Hughes C, Murphy A, Martin C, Fox E, Ring M, Sheils O, Loftus B, O'Leary J, Topoisomerase II-alpha expression increases with increasing Gleason score and with hormone insensitivity in prostate carcinoma, Journal of Clinical Pathology, 59, (7), 2006, p721 - 724
Pathology 2026: The future of laboratory medicine and academic pathology in, editor(s)John Wiley & Sons , Understanding disease, John Wiley & Sons, 2006, pp217 - 231, [O'Leary JJ]
O'Regan EM, Timon C, Sheils O, Codd M, O'Leary JJ, Toner M, Squamous cell carcinoma of the head and neck in young Irish adults, British Journal of Oral and Maxillofacial Surgery , 44, (3), 2006, p203 - 206
Astbury, K., Martin, C.M., Ring, M., Pilkington, L., Bolger, N., Sheils, O.M., O'Leary, J.J. , Future molecular aspects of cervical cytology , Current Diagnostic Pathology, 12, (2), 2006, p104-113
Tumour markers in cervical cancer in, editor(s)Jordan JA, Singer A , The Cervix, Blackwell Publishing, 2006, pp399 - 413, [O'Leary JJ, Astbury K, Prendiville W]
CGH array analysis of human tissues in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp523 - 528, [O'Regan, E, Martin, C.M., Finn, S, Smyth, P., Flavin, R., O'Leary, J.J. Sheils, O.]
O'Toole SA, Sheppard BL, Sheils O, O'Leary JJ, Spengler B, Christoffel V, Analysis of DNA in endometrial cancer cells treated with phyto-estrogenic compounds using comparative genomic hybridisation microarrays, Planta Medica, 71, (5), 2005, p435 - 439
Murphy, N., Ring, M., Heffron, C.C.B.B., Martin, C.M., McGuinness, E., Sheils, O., O'Leary, J.J., Quantitation of CDC6 and MCM5 mRNA in cervical intraepithelial neoplasia and invasive squamous cell carcinoma of the cervix, Modern Pathology , 18, (6), 2005, p844-849
Laser capture microdissection in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp489 - 493, [Sheils, O., Smyth, P., O'Regan, E.M.,Finn, S., Flavin, R., O'Leary, J.J.]
O'Toole SA, Dunn E, Sheppard BL, Sheils O, O'Leary JJ, Wuttke W,, Oestrogen regulated gene expression in normal and malignant endometrial tissue, Maturitas, 51, (2), 2005, p187 - 198
Mocanu EV, Adala S, O'Leary JJ, Womb with a view, Human Fertility (Camb)., 8, (1), 2005, p35 - 40
High density SNP and cDNA array analysis in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp515 - 521, [Sheils, O., Smyth, P., Sherlock, J., Martin, C.M., Finn, S., O'Regan, E.M., O'Leary, J.J.]
Murphy N, Ring M, Heffron CC, King B, Killalea AG, Hughes C, Martin CM,McGuinness E, Sheils O, O'Leary JJ, p16INK4A, CDC6, and MCM5: predictive biomarkers in cervical preinvasive, Journal of Clinical Pathology, 58, (5), 2005, p525 - 534
Smyth P, Finn S, Cahill S, O'Regan E, Flavin R, O'Leary JJ, Sheils O, ret/PTC and BRAF act as distinct molecular, time-dependant triggers in a sporadic Irish cohort of papillary thyroid carcinoma, International Journal of Surgical Pathology, 13, (1), 2005, p1 - 8
DNA Sequencing in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp531 - 539, [Martin, C.M., Picton, S.J. Sheils, O., O'Leary, J.J.]
Hughes C, Murphy A, Martin C, Sheils O, O'Leary J, Molecular pathology of prostate cancer, Journal of Clinical Pathology, 58, (7), 2005, p673 - 684
In-cell PCR in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp505 - 513, [O'Leary, J.J., Martin, C.M., Sheils, O.]
Real Time PCR gene analysis in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp495 - 504, [Martin, C.M., Sheils, O, O'Leary, J.J.]
Molecular markers in cervical dyskaryosis in, editor(s)Davies P.O.,Prendiville W , The Clinican's HPV handbook (vol 1), Parthenon Medical Publishing, 2005, pp73 - 88, [Murphy, N., Ring, M., Sheils, O., O'Leary, J.J.]
S. P. Finn, P. Smyth, E. O'Regan, S. Cahill, R. Flavin, J. O'Leary and O. Sheils, Array comparative genomic hybridisation analysis of gamma-irradiated human thyrocytes, Virchows Arch, 445, (4), 2004, p396-404
Bofin, A.M., Ytterhus, B., Martin, C., O'Leary, J.J., Hagmar, B.M., Detection and quantitation of HER-2 gene amplification and protein expression in breast carcinoma , American Journal of Clinical Pathology, 122, (1), 2004, p110-119
A. M. Cotter, C. M. Martin, J. O'Leary J and S. F. Daly, Increased fetal DNA in the maternal circulation in early pregnancy is associated with an increased risk of preeclampsia, American Journal of Obstetrics and Gynecology, 191, (2), 2004, p515-520
D. Kane, M. Gogarty, J. O'Leary, I. Silva, N. Bermingham, B. Bresnihan and O. Fitzgerald, Reduction of synovial sublining layer inflammation and proinflammatory cytokine expression in psoriatic arthritis treated with methotrexate, Arthritis and Rheumatism, 50, (10), 2004, p3286-3295
N. Murphy, C. C. Heffron, B. King, U. G. Ganuguapati, M. Ring, E. McGuinness, O. Sheils and J. J. O'Leary, P16(INK4A) positivity in benign, premalignant and malignant cervical glandular lesions: a potential diagnostic problem, Virchows Archiv, 445, (6), 2004, p610-615
Sheils, O.M., Finn, S., O'Leary, J.J., Quality-control issues for PCR-based assays in the molecular laboratory , 9, (3), 2003, p165-172
B. M. Byrne, A. Crowley, F. Taulo, J. Anthony, J. J. O'Leary and C. O'Herlihy, Fetal DNA quantitation in peripheral blood is not useful as a marker of disease severity in women with preeclampsia, Hypertension in pregnancy, 22, (2), 2003, p157-64
Murphy N, Ring M, Killalea AG, Uhlmann V, O'Donovan M, Mulcahy F, Turner M, Mc Guinness E, Griffin M, Martin, C, Sheils O, O'Leary JJ., p16INK4A as a marker for cervical dyskaryosis: CIN and cGIN in cervical biopsies and ThinPrep smears, Journal of Clinical Pathology, 56, (1), 2003, p56-63
Turner, M.J., Martin, C.M., O'Leary, J.J., Letter to the Editor [2] , 2003, - 118
P. Smyth, S. Finn, J. O'Leary and O. Sheils, Real-time analysis of beta- and gamma-catenin mRNA expression in ret/PTC-1 activated and nonactivated thyroid tissues, Diagnostic Molecular Pathology, 12, (1), 2003, p44-49
S. P. Finn, P. Smyth, J. O'Leary, E. C. Sweeney and O. Sheils, Ret/PTC chimeric transcripts in an Irish cohort of sporadic papillary thyroid carcinoma, Journal of Clinical Endocrinology and Metabolism, 88, (2), 2003, p938-941
O'Leary, J.J., Potential viral pathogenic mechanism for new variant inflammatory bowel disease [1] , 2003, - 248
J. Skinner, K. Luettich, M. Ring, J. J. O'Leary and M. J. Turner, Analysis of fetal DNA in the maternal venous blood for abnormalities of chromosomes 13, 16, 18 and 21 in first-trimester spontaneous miscarriage, Journal of obstetrics and gynaecology, 23, (3), 2003, p228-232
Turner, M.J., Martin C.M., O'Leary, J.J. , Detection of fetal Rhesus D gene in whole blood of women booking for routine antenatal care, European journal of obstetrics, gynecology, and reproductive biology, 108, (1), 2003, p29-32
Sheils, O., Finn, S., O'Leary, J., Nucleic acid microarrays: An overview, 9, (3), 2003, pPages 155-158
Martin CM, Uhlmann V, Killalea A, Sheils O, O'Leary JJ. , Detection of measles virus in children with ileo-colonic lymphoid nodular hyperplasia, enterocolitis and developmental disorder, Molecular psychiatry, 7 Suppl 2, 2002, pS47-s48
M. Ring, N. Bolger, M. O'Donnell, A. Malkin, N. Bermingham, E. Akpan, F. Mulcahy, M. J. Turner, M. Griffin and J. J. O'Leary, Evaluation of liquid-based cytology in cervical screening of high-risk populations: a split study of colposcopy and genito-urinary medicine populations, Cytopathology, 13, (3), 2002, p152-9
O. Sheils, P. Smyth, S. Finn, E. C. Sweeney and J. J. O'Leary, RET/PTC rearrangements in Hashimoto's thyroiditis, International Journal of Surgical Pathology, 10, (2), 2002, p167-8; author reply 168-9
Uhlmann*, V., Martin*, C.M., Sheils, O., Pilkington, L., Silva, I., Killalea, A., Murch, S.B.,Walker-Smith, J., Thomson, M., Wakefield, A.J., O'Leary, J.J. , Potential viral pathogenic mechanism for new variant inflammatory bowel disease, Molecular pathology, 55, (2), 2002, p84-90
J. Skinner, K. Luettich, M. Ring, J. J. O'Leary and M. J. Turner, Fetal DNA in maternal circulation of first-trimester spontaneous abortions, Obstetrics and gynecology, 97, (3), 2001, p460-463
M. O'Donovan, I. Silva, V. Uhlmann, N. Bermingham, K. Luttich, C. Martin, O. Sheils, A. Killalea, C. Kenny, S. Pileri and J. J. O'Leary, Expression profile of human herpesvirus 8 (HHV-8) in pyothorax associated lymphoma and in effusion lymphoma, Molecular pathology, 54, (2), 2001, p80-85
Smyth, P., Sheils, O., Finn, S., Martin, C., O 'Leary, J., Sweeney, E.C, Real time Quantitative Analysis of E-cadherin expression in ret/PTC-1-Activated Thyroid Neoplasms., International Journal of Surgical Pathology , 9, (4), 2001, p265-272
O'Leary J, Kennedy M, Howells D, Silva I, Uhlmann V, Luttich K, Biddolph S, Lucas S, Russell J, Bermingham N, O'Donovan M, Ring M, Kenny C, Sweeney M, Sheils O, Martin C, Picton S, Gatter K, Cellular localisation of HHV-8 in Castleman's disease: is there a link with lymph node vascularity?, Journal of Clinical Pathology - Molecular Pathology, 53, (2), 2000, p69-76
J. J. O'Leary, V. Uhlmann and A. J. Wakefield, Measles virus and autism, Lancet, 356, (9231), 2000, p772
Hackett, N.R., Sawy, T.B., Lee, L.Y., Silva, I., O'Leary, J., Rosengart, T.K., Crystal, R.G., Use of quantitative TaqMan real-time PCR to track the time-dependent distribution of gene transfer vectors in vivo , Molecular Therapy, 2, (6), 2000, p649-656
Uhlmann, V., Prasad, M., Silva, I., Luettich, K., Grande, L., Alonso, L., Thisted, M., Pluzek, K.J., Gorst, J., Ring, M., Sweeney, M., Kenny, C., Martin, C., Russell, J., Bermingham, N., O'Donovan, M., Sheils, O., O'Leary, J.J, Improved in situ detection method for telomeric tandem repeats in metaphase spreads and interphase nuclei, Molecular pathology, 53, (1), 2000, p48-50
Sheils, O.M., O'Leary, J.J., Sweeney, E.C., Differentiation of multicentric origin from intra-organ metastatic spread of hepatocellular carcinomas by comparative genomic hybridization, Journal of Pathology, 192, (1), 2000, p43-51
A. J. Wakefield, A. Anthony, S. H. Murch, M. Thomson, S. M. Montgomery, S. Davies, J. J. O'Leary, M. Berelowitz and J. A. Walker-Smith, Enterocolitis in children with developmental disorders, The American Journal of Gastroenterology, 95, (9), 2000, p2285-2295
O'Leary, J.J., Kennedy, M., Luttich, K., Uhlmann, V., Silva, I., Russell, J., Sheils, O., Ring, M., Sweeney, M., Kenny, C., Bermingham, N., Martin, C., O'Donovan, M., Howells, D., Picton, S., Lucas, S.B, Localisation of HHV-8 in AIDS related lymphadenopathy, Molecular Pathology, 53, (1), 2000, p43-47
O. M. Sheils, J. J. O'Leary and E. C. Sweeney, Assessment of ret/PTC-1 rearrangements in neoplastic thyroid tissue using TaqMan RT-PCR, The Journal of Pathology, 192, (1), 2000, p32-36
Kennedy, M.M., Biddolph, S., Lucas, S.B., Howells, D.D., Picton, S., O'D McGee, J., O'Leary, J.J., CD40 upregulation is independent of HHV-8 in the pathogenesis of Kaposi's sarcoma , Journal of Clinical Pathology - Molecular Pathology, 52, (1), 1999, p32-36
O'Leary, J.J., Shapiro, R.L., Ren, C.J., Chuang, N., Cohen, H.W., Potmesil, M., Antiangiogenic effects of camptothecin analogues 9-amino- 20(S)camptothecin, topotecan, and CPT-11 studied in the mouse cornea model , Clinical Cancer Research, 5, (1), 1999, p181-187
Prasad, M.L., Hyjek, E., Giri, D.D., Ying, L., O'Leary, J.J., Hoda, S.A., Double immunolabeling with cytokeratin and smooth-muscle actin in confirming early invasive carcinoma of breast , American Journal of Surgical Pathology, 23, (2), 1999, p176-181
Kennedy, M.M., Biddolph, S., Lucas, S.B., Howells, D.D., Picton, S., O'D McGee, J., Silva, I., (...), O'Leary, J.J., Cyclin D1 expression and HHV8 in Kaposi sarcoma , Journal of Clinical Pathology, 52, (8), 1999, p569-573
Ely, S.A., Powers, J., Lewis, D., Chang, S., Rubio, A., O'Leary, J., Knowles, D.M., Kaposi's sarcoma-associated herpesvirus-positive primary effusion lymphoma arising in the subarachnoid space, Human Pathology, 30, (8), 1999, p981-984
M. O'Donovan, J. M. Russell, J. J. O'Leary, J. A. Gillan, M. P. Lawler and E. F. Gaffney, Abl expression, tumour grade, and apoptosis in chondrosarcoma, Molecular Pathology, 52, (6), 1999, p341-4
O'Leary, J., Muggia, F.M., Camptothecins: A review of their development and schedules of administration, European Journal of Cancer , 34, (10), 1998, p1500-1508
Kennedy, M.M., Cooper, K., Howells, D.D., Picton, S., Biddolph, S., Lucas, S.B., McGee, J.O'D., O'Leary, J.J., Identification of HHV8 in early Kaposi's sarcoma: Implications for Kaposi's sarcoma pathogenesis , Journal of Clinical Pathology - Molecular Pathology, 51, (1), 1998, p14-20
O'Leary, J., Volm, M., Wasserheit, C., Muggia, F., Searching for Predictive Molecular Markers: Taxanes in Adjuvant and Neoadjuvant Therapies for Breast Cancer , Oncology Reports, 12, (1 SUPPL.1), 1998, p23-27
O'Leary, J.J., Landers, R.J., Crowley, M., Healy, I., O'Donovan, M., Healy, V., Kealy, W.F., (...), Doyle, C.T., Human papillomavirus and mixed epithelial tumors of the endometrium , Human Pathology, 29, (4), 1998, p383-389
O. Flore, S. Rafii, S. Ely, J. J. O'Leary, E. M. Hyjek and E. Cesarman, Transformation of primary human endothelial cells by Kaposi's sarcoma-associated herpesvirus, Nature, 394, (6693), 1998, p588-92
Uhlmann, V., Rolfs, A., Mix, E., Silva, I., Hully, J., Lu, L., Lohman, K., (...), O'Leary, J.J., A novel, rapid in cell RNA amplification technique for the detection of low copy mRNA transcripts, Journal of Clinical Pathology - Molecular Pathology, 51, (3), 1998, p160-163
O'Leary, J.J., Silva, I., Uhlmann, V., Prasad, M., Luttich, K., Maffei, A., Picton, S., HHV-8 in multiple myeloma: Is this the first paracrine model of human tumorigenesis and do Koch's postulates apply? , Journal of Clinical Pathology - Molecular Pathology, 51, (4), 1998, p201-203
Kennedy, M.M., O'Leary, J.J., Oates, J.L., Lucas, S.B., Howells, D.D., Picton, S., McGee, J.O'D., Human herpes virus 8 (HHV-8) in Kaposi's sarcoma: Lack of association with Bcl-2 and p53 protein expression , Journal of Clinical Pathology - Molecular Pathology, 51, (3), 1998, p155-159
Uhlmann, V., Silva, I., Luttich, K., Picton, S., O'Leary, J.J., In cell amplication , Journal of Clinical Pathology - Molecular Pathology, 51, (3), 1998, p119-130
O'Leary, J.J., Landers, R.J., Silva, I., Uhlmann, V., Crowley, M., Healy, I., Luttich, K., Molecular analysis of ras oncogenes in CIN III and in stage I and II invasive squamous cell carcinoma of the uterine cervix , Journal of Clinical Pathology, 51, (8), 1998, p576-582
O'Leary, J.J., Engels, K., Dada, M.A., The polymerase chain reaction in pathology , Journal of Clinical Pathology, 50, (10), 1997, p805-810
Kennedy, M.M., Lucas, S.B., Russell-Jones, R., Howells, D.D., Picton, S.J., Bardon, A., Comley, I.L., (...), O'Leary, J.J., HHV8 and female Kaposi's sarcoma , Journal of Pathology, 183, (4), 1997, p447-452
J. J. O'Leary, R. J. Landers, M. Crowley, I. Healy, W. F. Kealy, J. Hogan, C. Cullinane, P. Kelehan and C. T. Doyle, Genotypic mapping of HPV and assessment of EBV prevalence in endocervical lesions, Journal of Clinical Pathology, 50, (11), 1997, p904-910
O'Leary, J.J., Landers, R.J., Crowley, M., Healy, I., Kealy, W.F., Hogan, J., Doyle, C.T., Alterations in exon 1 of c-myc and expression of p62(c-myc) in cervical squamous cell carcinoma , Journal of Clinical Pathology , 50, (11), 1997, p896-903
O'Leary, J.J., Landers, R.J., Chetty, R., In situ amplification in cytological preparations , Cytopathology, 8, (3), 1997, p148-160
O'Leary, J.J., Kaposi's sarcoma associated herpes virus (KSHV/HHV 8) : Epidemiology, molecular biology and tissue distribution , Journal of Clinical Pathology - Molecular Pathology , 50, (1), 1997, p4-8
Boshoff, C., Talbot, S., Kennedy, M., O'Leary, J., Schulz, T., Chang, Y., HHV8 and skin cancers in immunosuppressed patients. , Lancet, 348, (9020), 1996, p138
O'Leary, J.J., Seeking the cause of Kaposi's sarcoma , Nature Medicine, 2, (8), 1996, p862-863
Koreth, J., O'Leary, J.J., McGee, J.O., Microsatellites and PCR genomic analysis , Journal of Pathology, 178, (3), 1996, p239-248
O'Leary, J.J., Chetty, R., Graham, A.K., McGee, J.O'D., In situ PCR: Pathologist's dream or nightmare? , Journal of Pathology, 178, (1), 1996, p11-20
Chetty, R., O'Leary, J.J., Biddolph, S.C., Gatter, K.C., Immunohistochemical detection of p53 and Bcl-2 proteins in Hashimoto's thyroiditis and primary thyroid lymphomas , Journal of Clinical Pathology, 48, (3), 1995, p239-241
C. Boshoff, T. F. Schulz, M. M. Kennedy, A. K. Graham, C. Fisher, A. Thomas, J. O. McGee, R. A. Weiss and J. J. O'Leary, Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cells, Nature Medicine, 1, (12), 1995, p1274-1278
Chetty, R., Slavin, J.L., O'Leary, J.J., Ansari, N.A., Gatter, K.C., Primary Hodgkin's disease of the lung , Pathology, 27, (2), 1995, p111-114
O'Leary, J.J., Browne, G., Landers, R.J., Crowley, M., Healy, I.B., Street, J.T., Pollock, A.M., (...), Doyle, C.T., The importance of fixation procedures on DNA template and its suitability for solution-phase polymerase chain reaction and PCR in situ hybridization , Histochemical Journal , 26, (4), 1994, p337-346
O'Leary, J.J., Browne, G., Johnson, M.I., Landers, R.J., Crowley, M., Healy, I., Street, J.T., (...), Doyle, C.T., PCR in situ hybridisation detection of HPV 16 in fixed CaSki and fixed SiHa cell lines, Journal of Clinical Pathology, 47, (10), 1994, p933-938
O'Leary, J.J., Browne, G., Landers, R., Crowley, M., Healy, I., Johnson, M.I., Doyle, C.T., New nucleic acid amplification techniques in diagnostic pathology, Journal of the European Academy of Dermatology and Venereology, 3, (1), 1994, p78-86
Landers, R.J., O'Leary, J.J., Crowley, M., Healy, I., Annis, P., Burke, L., O'Brien, D., (...), Doyle, C.T., Epstein-Barr virus in normal, pre-malignant, and malignant lesions of the uterine cervix , Journal of Clinical Pathology, 46, (10), 1993, p931-935
Doyle, C.T., O'Leary, J.J., The search for the universal fixative or 'magic juice' , Journal of Pathology , 166, (4), 1992, p331-332
Research Expertise
Description
Biomarkers of disease. Cervical Cancer. Development of array technologies. Molecular pathology. Prostate cancer.Recognition
Representations
Member, DMMC Cancer Principal Investigators, Trans-institutional grouping of Principal Investigators leading research on Cancer themes
Member, Core Technology PI's, DMMC Principal Investigators leading the development of core technology platforms.
Member, Centre for Molecular Research in Cancer (Proposed), This consortium combines researchers with common interest in understanding cell cycle signaling and regulation with specific focus on two key cancer-related processes (cell cycle control, apoptosis) and/or three specific malignancy types (oesophageal, prostate and haematological).
Invitee, Breast Cancer Consortium (Proposed), Investigators to be invited to participate in Breast Cancer workshop with a view to establishing formal consortium and informal individual collaborations.Last updated : 19 November 2004. Extract from DMMC Research Database