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2014

M. D. Teasdale, N. L. van Doorn, S. Fiddyment, C. C. Webb, T. O'Connor, M. Hofreiter, M. J. Collins, D. G. Bradley Paging through history: parchment as a reservoir of ancient DNA for next generation sequencing Phil. Trans. R. Soc., Dec 2014 B 370: 20130379 DOI: 10.1098/rstb.2013.0379
Video
media coverage


Ian W Richardson, Dan G Bradley, Isabella M Higgins, Simon J More, Jennifer McClure and Donagh P Berry Variance components for susceptibility to Mycobacterium bovis infection in dairy and beef cattle Genetics Selection Evolution 2014, 46:77 doi:10.1186/s12711-014-0077-1


Sanderson ND, Norman PJ, Guethlein LA, Ellis SA, Williams C, Breen M, Park SD, Magee DA, Babrzadeh F, Warry A, Watson M, Bradley DG, MacHugh DE, Parham P, Hammond JA Definition of the Cattle Killer Cell Ig-like Receptor Gene Family: Comparison with Aurochs and Human Counterparts J Immunol. 2014 Nov 14. pii: 1401980 PMID:25398326


Cristina Gamba, Eppie R. Jones, Matthew D. Teasdale, Russell L. McLaughlin, Gloria Gonzalez-Fortes, Valeria Mattiangeli, László Domboróczki, Ivett K?vári, Ildikó Pap, Alexandra Anders, Alasdair Whittle, János Dani, Pál Raczky, Thomas F. G. Higham, Michael Hofreiter, Daniel G. Bradley, Ron Pinhasi Genome flux and stasis in a five millennium transect of European prehistory Nature Communications October 2014 PMID:25334030
media coverage and data


McLaughlin RL, Kenna KP, Vajda A, Bede P, Elamin M, Cronin S, Donaghy CG, Bradley DG, Hardiman O. A second-generation Irish genome-wide association study for amyotrophic lateral sclerosis. Neurobiol Aging 2014 Sept. DOI:10.1016/j.neurobiolaging.2014.08.030.


Martiniano R, Coelho C, Ferreira MT, Neves MJ, Pinhasi R, Bradley DG. Genetic Evidence of African Slavery at the Beginning of the Trans-Atlantic Slave Trade. Sci Rep. 2014 Aug 8;4:5994. PMID:25104065


Bede P, Elamin M, Byrne S, McLaughlin RL, Kenna K, Vajda A, Fagan A, Bradley DG, Hardiman O Patterns of cerebral and cerebellar white matter degeneration in ALS J Neurol Neurosurg Psychiatry. 2014 Jul 21. pii: jnnp-2014-308172. PMID:25053771


Gerbault P, Allaby RG, Boivin N, Rudzinski A, Grimaldi IM, Pires JC, Climer Vigueira C, Dobney K, Gremillion KJ, Barton L, Arroyo-Kalin M, Purugganan MD, Rubio de Casas R, Bollongino R, Burger J, Fuller DQ, Bradley DG, Balding DJ, Richerson PJ, Gilbert MT, Larson G, Thomas MG. Storytelling and story testing in domestication. Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6159-64. PMID:24753572


Larson G, Bradley DG. How much is that in dog years? The advent of canine population genomics. PLoS Genet. 2014 Jan;10(1) PMID:24453989


2013

Fahey C, Byrne S, McLaughlin R, Kenna K, Shatunov A, Donohoe G, Gill M, Al-Chalabi A, Bradley DG, Hardiman O, Corvin AP, Morris DW. Analysis of the hexanucleotide repeat expansion and founder haplotype at C9ORF72 in an Irish psychosis case-control sample. Neurobiol Aging. 2013 Dec 12. [Epub ahead of print] PMID:24411481


Purfield DC, Bradley DG, Kearney JF, Berry DP. Genome-wide association study for calving traits in Holstein-Friesian dairy cattle. Animal. 2013 Nov 20:1-12. [Epub ahead of print] PMID:24256561


Meredith BK, Berry DP, Kearney F, Finlay EK, Fahey AG, Bradley DG, Lynn DJ. A genome-wide association study for somatic cell score using the Illumina high-density bovine beadchip identifies several novel QTL potentially related to mastitis susceptibility. Front Genet. 2013 Nov 6;4:229. doi: 10.3389/fgene.2013.00229. PMID:24223582


Bede P, Elamin M, Byrne S, McLaughlin RL, Kenna K, Vajda A, Pender N, Bradley DG, Hardiman O. Basal ganglia involvement in amyotrophic lateral sclerosis. Neurology. 2013 Nov 8. [Epub ahead of print] PMID:24212388


Zhang H, Paijmans JL, Chang F, Wu X, Chen G, Lei C, Yang X, Wei Z, Bradley DG, Orlando L, O'Connor T, Hofreiter M. Morphological and genetic evidence for early Holocene cattle management in Northeastern China. Nat Commun. 2013;4:2755. doi: 10.1038/ncomms3755. PMID:24202175


Edwards CJ, Soulsbury CD, Statham MJ, Ho SY, Wall D, Dolf G, Iossa G, Baker PJ, Harris S, Sacks BN, Bradley DG. Temporal genetic variation of the red fox, Vulpes vulpes, across western Europe and the British Isles. Quat Sci Rev. 2012 Dec 4;57(100):95-104. PMID:24068852


Vegh P, Foroushani AB, Magee DA, McCabe MS, Browne JA, Nalpas NC, Conlon KM, Gordon SV, Bradley DG, Machugh DE, Lynn DJ. Profiling microRNA expression in bovine alveolar macrophages using RNA-seq. Vet Immunol Immunopathol. 2013 Oct 1;155(4):238-44. doi: 10.1016/j.vetimm.2013.08.004. Epub 2013 Aug 24. PMID:24021155


McLaughlin RL, Kenna KP, Vajda A, Byrne S, Bradley DG, Hardiman O. UBQLN2 mutations are not a frequent cause of amyotrophic lateral sclerosis in Ireland. Neurobiol Aging. 2013 Aug 21. doi:pii: S0197-4580(13)00328-X. 10.1016/j.neurobiolaging.2013.07.023. PMID:23973441


Kenna KP, McLaughlin RL, Byrne S, Elamin M, Heverin M, Kenny EM, Cormican P, Morris DW, Donaghy CG, Bradley DG, Hardiman O. Delineating the genetic heterogeneity of ALS using targeted high-throughput sequencing. J Med Genet. 2013 Jul 23. doi: 10.1136/jmedgenet-2013-101795. PMID:23881933


Bede P, Bokde AL, Byrne S, Elamin M, McLaughlin RL, Kenna K, Fagan AJ, Pender N, Bradley DG, Hardiman O Multiparametric MRI study of ALS stratified for the C9orf72 genotype. Neurology. 2013 Jul 23;81(4):361-9. doi 10.1212/WNL.0b013e31829c5eee. PMID:23771489


Connell S, Meade KG, Allan B, Lloyd AT, Downing T, O'Farrelly C, Bradley DG. Genome-Wide Association Analysis of Avian Resistance to Campylobacter jejuni Colonization Identifies Risk Locus Spanning the CDH13 Gene. G3 (Bethesda). 2013 Mar 27. doi:pii: g3.113.006031v1. 10.1534/g3.113.006031. PMID:23550144


Kenna KP, McLaughlin RL, Hardiman O, Bradley DG. Using Reference Databases of Genetic Variation to Evaluate the Potential Pathogenicity of Candidate Disease Variants. Hum Mutat. 2013 Feb 27. doi: 10.1002/humu.22303. PMID:23447461


2012

le Roex N, Noyes H, Brass A, Bradley DG, Kemp SJ, Kay S, van Helden PD, Hoal EG. Novel SNP Discovery in African Buffalo, Syncerus caffer, using high-throughput Sequencing. PLoS One. 2012;7(11):e48792. doi: 10.1371/journal.pone.0048792. Epub 2012 Nov 7. PMID:23144973


Purfield DC, Berry DP, McParland S, Bradley DG. Runs of homozygosity and population history in cattle. BMC Genet. 2012 Aug 14;13(1):70. [Epub ahead of print] PMID:22888858


Connell S, Meade KG, Allan B, Lloyd AT, Kenny E, Cormican P, Morris DW, Bradley DG, O'Farrelly C. Avian Resistance to Campylobacter jejuni Colonization Is Associated with an Intestinal Immunogene Expression Signature Identified by mRNA Sequencing. PLoS One. 2012;7(8):e40409. Epub 2012 Aug 1. PMID:22870198


Hall SJ, Lenstra JA, Deeming DC; European Cattle Genetic Diversity Consortium. Prioritization based on neutral genetic diversity may fail to conserve important characteristics in cattle breeds. J Anim Breed Genet. 2012 Jun;129(3):218-25. doi: 10.1111/j.1439-0388.2011.00949.x. Epub 2011 Aug 15. PMID:22583326


Meredith BK, Kearney FJ, Finlay EK, Bradley DG, Fahey AG, Berry DP, Lynn DJ. Genome-wide associations for milk production and somatic cell score in Holstein-Friesian cattle in Ireland. BMC Genet. 2012 Mar 26;13(1):21. PMID:22449276


Finlay EK, Berry DP, Wickham B, Gormley EP, Bradley DG. A genome wide association scan of bovine tuberculosis susceptibility in Holstein-Friesian dairy cattle. PLoS One. 2012;7(2):e30545. Epub 2012 Feb 15. PMID:22355315


Byrne S, Elamin M, Bede P, Shatunov A, Walsh C, Corr B, Heverin M, Jordan N, Kenna K, Lynch C, McLaughlin RL, Iyer PM, O'Brien C, Phukan J, Wynne B, Bokde AL, Bradley DG, Pender N, Al-Chalabi A, Hardiman O. Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study. Lancet Neurol. 2012 Mar;11(3):232-40. Epub 2012 Feb 3. PMID:22305801


Bower MA, McGivney BA, Campana MG, Gu J, Andersson LS, Barrett E, Davis CR, Mikko S, Stock F, Voronkova V, Bradley DG, Fahey AG, Lindgren G, MacHugh DE, Sulimova G, Hill EW. The genetic origin and history of speed in the Thoroughbred racehorse. Nat Commun. 2012 Jan 24;3:643. doi: 10.1038/ncomms1644. PMID:22273681


2011

Busby GB, Brisighelli F, Sánchez-Diz P, Ramos-Luis E, Martinez-Cadenas C, Thomas MG, Bradley DG, Gusmăo L, Winney B, Bodmer W, Vennemann M, Coia V, Scarnicci F, Tofanelli S, Vona G, Ploski R, Vecchiotti C, Zemunik T, Rudan I, Karachanak S, Toncheva D, Anagnostou P, Ferri G, Rapone C, Hervig T, Moen T, Wilson JF, Capelli C. The peopling of Europe and the cautionary tale of Y chromosome lineage R-M269. Proc Biol Sci. 2011 Aug 24. [Epub ahead of print]. PMID:21865258 Direct link


Edwards CJ, Suchard MA, Lemey P, Welch JJ, Barnes I, Fulton TL, Barnett R, O'Connell TC, Coxon P, Monaghan N, Valdiosera CE, Lorenzen ED, Willerslev E, Baryshnikov GF, Rambaut A, Thomas MG, Bradley DG, Shapiro B. Ancient hybridization and an Irish origin for the modern polar bear matriline. Curr Biol. 2011 Aug 9;21(15):1251-8. Epub 2011 Jul 7. PMID:21737280.


Noyes H, Brass A, Obara I, Anderson S, Archibald AL, Bradley DG, Fisher P, Freeman A, Gibson J, Gicheru M, Hall L, Hanotte O, Hulme H, McKeever D, Murray C, Oh SJ, Tate C, Smith K, Tapio M, Wambugu J, Williams DJ, Agaba M, Kemp SJ. Genetic and expression analysis of cattle identifies candidate genes in pathways responding to Trypanosoma congolense infection. Proc Natl Acad Sci U S A. 2011 May 31;108(22):9304-9. Epub 2011 May 18. PMID:21593421.


Edwards CJ, Ginja C, Kantanen J, Pérez-Pardal L, Tresset A, Stock F; European Cattle Genetic Diversity Consortium, Gama LT, Penedo MC, Bradley DG, Lenstra JA, Nijman IJ. Dual origins of dairy cattle farming--evidence from a comprehensive survey of European Y-chromosomal variation. PLoS One. 2011 Jan 6;6(1):e15922. PMID: 21253012.


2010

McLaughlin RL, Phukan J, McCormack W, Lynch DS, Greenway M, Cronin S, Saunders J, Slowik A, Tomik B, Andersen PM, Bradley DG, Jakeman P, Hardiman O. Angiogenin levels and ANG genotypes: dysregulation in amyotrophic lateral sclerosis. PLoS One. 2010 Nov 10;5(11):e15402. PMID: 21085671.


Magee DA, Berkowicz EW, Sikora KM, Sweeney T, Kenny DA, Kelly AK, Evans RD, Wickham BW, Bradley DG, Spillane C, MacHugh DE. High concordance of bovine single nucleotide polymorphism genotypes generated using two independent genotyping strategies. Anim Biotechnol. 2010 Oct;21(4):257-62. PMID: 20967645.


Blauw HM, Al-Chalabi A, Andersen PM, van Vught PW, Diekstra FP, van Es MA, Saris CG, Groen EJ, van Rheenen W, Koppers M, Van't Slot R, Strengman E, Estrada K, Rivadeneira F, Hofman A, Uitterlinden AG, Kiemeney LA, Vermeulen SH, Birve A, Waibel S, Meyer T, Cronin S, McLaughlin RL, Hardiman O, Sapp PC, Tobin MD, Wain LV, Tomik B, Slowik A, Lemmens R, Rujescu D, Schulte C, Gasser T, Brown RH Jr, Landers JE, Robberecht W, Ludolph AC, Ophoff RA, Veldink JH, van den Berg LH. A large genome scan for rare CNVs in amyotrophic lateral sclerosis. Hum Mol Genet. 2010 Oct 15;19(20):4091-9. PMID: 20685689.


Tong P, Prendergast JG, Lohan AJ, Farrington SM, Cronin S, Friel N, Bradley DG, Hardiman O, Evans A, Wilson JF, Loftus B. Sequencing and analysis of an Irish human genome Genome Biol. 2010 Sep 7;11(9) PMID: 20822512.


Murray C, Huerta-Sanchez E, Casey F, Bradley DG. Cattle demographic history modelled from autosomal sequence variation. Philos Trans R Soc Lond B Biol Sci. 2010 Aug 27;365(1552):2531-9. PMID: 20643743.


Michael G. Campana, Mim A. Bower , Melanie J. Bailey , Frauke Stock , Tamsin C. O’Connell, Ceiridwen J. Edwards, Caroline Checkley-Scott, Barry Knight, Matthew Spencer,Christopher J. Howe A flock of sheep, goats and cattle: ancient DNA analysis reveals complexities of historical parchment manufacture. J. Arch. Sci. 2010. 37:1317-1325.


Downing T, Lloyd AT, O'Farrelly C, Bradley DG. The differential evolutionary dynamics of avian cytokine and TLR gene classes. J Immunol. 2010 Jun 15;184(12):6993-7000. PMID: 20483729


Groeneveld LF, Lenstra JA, Eding H, Toro MA, Scherf B, Pilling D, Negrini R, Finlay EK, Jianlin H, Groeneveld E, Weigend S; GLOBALDIV Consortium. Genetic diversity in farm animals--a review Anim Genet. 2010 May;41 Suppl 1:6-31. Review PMID: 20500753


Downing T, O'Farrelly C, Bhuiyan AK, Silva P, Naqvi AN, Sanfo R, Sow RS, Podisi B, Hanotte O, Bradley DG. Variation in chicken populations may affect the enzymatic activity of lysozyme. Anim Genet. 2010 Apr 1;41(2):213-7. PMID: 19845599


Edwards CJ, Magee DA, Park SD, McGettigan PA, Lohan AJ, Murphy A, Finlay EK, Shapiro B, Chamberlain AT, Richards MB, Bradley DG, Loftus BJ, Machugh DE. A complete mitochondrial genome sequence from a mesolithic wild aurochs (Bos primigenius). PLoS One. 2010 Feb 17;5(2):e9255. PMID: 20174668


Chen S, Lin BZ, Baig M, Mitra B, Lopes RJ, Santos AM, Magee DA, Azevedo M, Tarroso P, Sasazaki S, Ostrowski S, Mahgoub O, Chaudhuri TK, Zhang YP, Costa V, Royo LJ, Goyache F, Luikart G, Boivin N, Fuller DQ, Mannen H, Bradley DG, Beja-Pereira A. Zebu cattle are an exclusive legacy of the South Asia neolithic. Mol Biol Evol. 2010 Jan;27(1):1-6. PMID: 19770222


2009

Downing T, Cormican P, O'Farrelly C, Bradley DG, Lloyd AT. Evidence of the adaptive evolution of immune genes in chicken. BMC Res Notes. 2009 Dec 15;2:254. PMID: 20003477


Kantanen J, Edwards CJ, Bradley DG, Viinalass H, Thessler S, Ivanova Z, Kiselyova T, Cinkulov M, Popov R, Stojanovic S, Ammosov I, Vilkki J. Maternal and paternal genealogy of Eurasian taurine cattle (Bos taurus). Heredity. 2009 Nov;103(5):404-15. PMID: 19603063


van Es MA, Veldink JH, Saris CG, Blauw HM, van Vught PW, Birve A, Lemmens R, Schelhaas HJ, Groen EJ, Huisman MH, van der Kooi AJ, de Visser M, Dahlberg C, Estrada K, Rivadeneira F, Hofman A, Zwarts MJ, van Doormaal PT, Rujescu D, Strengman E, Giegling I, Muglia P, Tomik B, Slowik A, Uitterlinden AG, Hendrich C, Waibel S, Meyer T, Ludolph AC, Glass JD, Purcell S, Cichon S, Nöthen MM, Wichmann HE, Schreiber S, Vermeulen SH, Kiemeney LA, Wokke JH, Cronin S, McLaughlin RL, Hardiman O, Fumoto K, Pasterkamp RJ, Meininger V, Melki J, Leigh PN, Shaw CE, Landers JE, Al-Chalabi A, Brown RH Jr, Robberecht W, Andersen PM, Ophoff RA, van den Berg LH. Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nat Genet. 2009 Oct;41(10):1083-7. PMID: 19734901


Stock F, Edwards CJ, Bollongino R, Finlay EK, Burger J, Bradley DG. Cytochrome b sequences of ancient cattle and wild ox support phylogenetic complexity in the ancient and modern bovine populations. Anim Genet. 2009 Oct;40(5):694-700. PMID: 19456314


Cormican P, Lloyd AT, Downing T, Connell SJ, Bradley D, O'Farrelly C. The avian Toll-Like receptor pathway--subtle differences amidst general conformity. Dev Comp Immunol. 2009 Sep;33(9):967-73. PMID: 19539094


Downing T, Lynn DJ, Connell S, Lloyd AT, Bhuiyan AK, Silva P, Naqvi AN, Sanfo R, Sow RS, Podisi B, Hanotte O, O'Farrelly C, Bradley DG. Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus. BMC Evol Biol. 2009 Jun 15;9:136. PMID: 19527513


Downing T, Lynn DJ, Connell S, Lloyd AT, Bhuiyan AK, Silva P, Naqvi AN, Sanfo R, Sow RS, Podisi B, O'Farrelly C, Hanotte O, Bradley DG. Contrasting evolution of diversity at two disease-associated chicken genes. Immunogenetics. 2009 Apr;61(4):303-14. PMID: 19247647


Bovine HapMap Consortium. Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds. Science. 2009;324(5926):528-532. PMID: 19390050


Bovine Genome Sequencing and Analysis Consortium. The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science. 2009;324(5926):522-528. PMID: 19390049


2008

Freeman AR, Lynn DJ, Murray C, Bradley DG. Detecting the effects of selection at the population level in six bovine immune genes. BMC Genet. 2008 Oct 6;9(1):62 [Epub ahead of print]. PMID:18838007


Mattiangeli V, McEvoy B, Bradley DG. Irish genetic affinities : the mosaic genome. Ir Nat J Spec Suppl. 2008; pg127-133.


Cronin S, Blauw HM, Veldink JH, van Es MA, Ophoff RA, Bradley DG, van den Berg LH, Hardiman O. Analysis of genome-wide copy number variationin Irish and Dutch ALS populations. Hum Mol Genet. 2008 Aug 21 [Epub ahead of print]. PMID:18689356


McEvoy B, Simms K, Bradley DG. Genetic investigation of the patrilineal kinship structure of early medieval Ireland. Am J Phys Anthropol. 2008 Aug;136(4):415-22. Epub 2008 Mar 18. PMID: 18350585


Cronin S, Berger S, Ding J, Schymick JC, Washecka N, Hernandez DG, Greenway MJ, Bradley DG, Traynor BJ, Hardiman O. A genome-wide association study of sporadic ALS in a homogenous Irish population. Hum Mol Genet. 2008 Mar 1;17(5):768-74. Epub 2007 Dec 5. PMID: 18057069


2007

Larson G, Albarella U, Dobney K, Rowley-Conwy P, Schibler J, Tresset A, Vigne JD, Edwards CJ, Schlumbaum A, Dinu A, Balaçsescu A, Dolman G, Tagliacozzo A, Manaseryan N, Miracle P, Van Wijngaarden-Bakker L, Masseti M, Bradley DG, Cooper A. Ancient DNA, pig domestication, and the spread of the Neolithic into Europe. Proc Natl Acad Sci USA. 2007 Sep 25;104(39):15276-81. Epub 2007 Sep 13. PMID: 17855556


Finlay EK, Gaillard C, Vahidi SM, Mirhoseini SZ, Jianlin H, Qi XB, El-Barody MA, Baird JF, Healy BC, Bradley DG. Bayesian inference of population expansions in domestic bovines. Biol. Lett. (2007) Aug 22; 3(4):449-52. PMID: 17535790


Bauchet M, McEvoy B, Pearson LN, Quillen EE, Sarkisian T, Hovhannesyan K, Deka R, Bradley DG, Shriver MD. Measuring European population stratification with microarray genotype data. Am J Hum Genet. 2007 May;80(5):948-56. Epub 2007 Mar 22. PMID: 17436249


Edwards CJ, Bollongino R, Scheu A, Chamberlain A, Tresset A, Vigne J-D, Baird JF, Larson G, Ho SYW, Heupink TH, Shapiro B, Freeman AR, Thomas, MG, Arbogast R-M, Arndt B, Bartosiewicz L, Benecke N, Budja M, Chaix L, Choyke AM, Coqueugniot E, Döhle H-J, Göldner H, Hartz S, Helmer D, Herzig B, Hongo H, Mashkour M, Özdogan M, Pucher E, Roth G, Schade-Lindig S, Schmölcke U, Schulting R, Stephan E, Uerpmann H-P, Vörös I, Voytek, B, Bradley DG, Burger J. Mitochondrial DNA analysis shows a Near Eastern Neolithic origin for domestic cattle and no indication of domestication of European aurochs. Proc Biol Sci. 2007 Apr 3;Series B 274, 1377-1385 [Epub ahead of print] PMID: 17412685


Lynn DJ, Bradley DG. Discovery of alpha-defensins in basal mammals. Dev Comp Immunol. 2007 Mar 2 [Epub ahead of print]. PMID: 17367857


Cruz F, Bradley DG, Lynn DJ. Evidence of positive selection on the Atlantic salmon CD3gammadelta gene. Immunogenetics. 2007 Mar;59(3):225-32. Epub 2007 Jan 9. PMID: 17211637


Norton HL, Kittles RA, Parra E, McKeigue P, Mao X, Cheng K, Canfield VA, Bradley DG, McEvoy B, Shriver MD. Genetic evidence for the convergent evolution of light skin in Europeans and East Asians. Mol Biol Evol. 2007 Mar;24(3):710-22. Epub 2006 Dec 20. PMID: 17182896


Negrini R, Nijman IJ, Milanesi E, Moazami-Goudarzi K, Williams JL, Erhardt G, Dunner S, Rodellar C, Valentini A, Bradley DG, Olsaker I, Kantanen J, Ajmone-Marsan P, Lenstra JA : European Cattle Genetic Diversity Consortium. Differentiation of European cattle by AFLP fingerprinting. Anim Genet. 2007 Feb;38(1):60-6. PMID: 17257190


2006

McEvoy B, Brady C, Moore LT, Bradley DG. The scale and nature of Viking settlement in Ireland from Y-chromosome admixture analysis. Eur J Hum Genet. 2006 Dec;14(12):1228-94. Epub 2006 Sep 6. PMID: 16957681


McGahern AM, Edwards CJ, Bower MA, Heffernan A, Park SD, Brophy PO, Bradley DG, Machugh DE, Hill EW. Mitochondrial DNA sequence diversity in extant Irish horse populations and in ancient horses. Anim Genet. 2006 Oct;37(5):498-502. PMID: 16978181


McGahern A, Bower MA, Edwards CJ, Brophy PO, Sulimova G, Zakharov I, Vizuete-Forster M, Levine M, Li S, MacHugh DE, Hill EW. Evidence for biogeographic patterning of mitochondrial DNA sequences in Eastern horse populations. Anim Genet. 2006 Oct;37(5):494-7. PMID: 16978180


Mattiangeli V, Ryan AW, McManus R, Bradley DG. A genome-wide approach to identify genetic loci with a signature of natural selection in the Irish population. Genome Biol. 2006;7(8):R74. Epub 2006 Aug 11. PMID: 16904005


Pereira F, Davis SJ, Pereira L, McEvoy B, Bradley DG, Amorim A. Genetic signatures of a Mediterranean influence in Iberian Peninsula sheep husbandry. Mol Biol Evol. 2006 Jul;23(7):1420-6. Epub 2006 May 3. PMID: 16672283


Freeman AR, Hoggart CJ, Hanotte O, Bradley DG. Assessing the relative ages of admixture in the bovine hybrid zones of Africa and the Near East using X chromosome haplotype mosaicism. Genetics. 2006 Jul;173(3):1503-10. Epub 2006 Apr 2. PMID: 16582445


Pereira L, Richards M, Goios A, Alonso A, Albarran C, Garcia O, Behar DM, Golge M, Hatina J, Al-Gazali L, Bradley DG, Macaulay V, Amorim A. Evaluating the forensic informativeness of mtDNA haplogroup H sub-typing on a Eurasian scale. Forensic Sci Int. 2006 May 25;159(1):43-50. Epub 2005 Aug 1. PMID: 16076538


Zeder MA, Emshwiller E, Smith BD, Bradley DG. Documenting domestication: the intersection of genetics and archaeology. Trends Genet. 2006 Mar;22(3):139-55. Epub 2006 Feb 3. PMID: 16458995


McEvoy B, Bradley DG. Y-chromosomes and the extent of patrilineal ancestry in Irish surnames. Hum Genet. 2006 Mar;119(1-2):212-9. Epub 2006 Jan 12. PMID: 16408222


Ryan AW, Mapp J, Moyna S, Mattiangeli V, Kelleher D, Bradley DG, McManus R. Levels of interpopulation differentiation among different functional classes of immunologically important genes. Genes Immun. 2006 Mar;7(2):179-83. PMID: 16222342


Moore LT, McEvoy B, Cape E, Simms K, Bradley DG. A y-chromosome signature of hegemony in Gaelic Ireland. Am J Hum Genet. 2006 Feb;78(2):334-8. Epub 2005 Dec 8. PMID: 16358217


Freeman AR, Bradley DG, Nagda S, Gibson JP, Hanotte O. Combination of multiple microsatellite data sets to investigate genetic diversity and admixture of domestic cattle. Anim Genet. 2006 Feb;37(1):1-9. PMID: 16441289


Bollongino R, Edwards CJ, Alt KW, Burger J, Bradley DG. Early history of European domestic cattle as revealed by ancient DNA. Biol. Lett. (2006) 2, 155–159. PMID: 17148352


2005

Lister AM, Edwards CJ, Nock DA, Bunce M, van Pijlen IA, Bradley DG, Thomas MG, Barnes I. The phylogenetic position of the 'giant deer' Megaloceros giganteus. Nature. 2005 Dec 8;438(7069):850-3. Epub 2005 Sep 4. PMID: 16148942


Gotherstrom A, Anderung C, Hellborg L, Elburg R, Smith C, Bradley DG, Ellegren H. Cattle domestication in the Near East was followed by hybridization with aurochs bulls in Europe. Proc Biol Sci. 2005 Nov 22;272(1579):2345-50. PMID: 16243693


Cymbron T, Freeman AR, Isabel Malheiro M, Vigne JD, Bradley DG. Microsatellite diversity suggests different histories for Mediterranean and Northern European cattle populations. Proc Biol Sci. 2005 Sep 7;272(1574):1837-43. PMID: 16096097


McEvoy B, Edwards CJ. Human migration: reappraising the Viking image. Heredity. 2005 Aug;95(2):111-2. PMID: 15931243


Pereira F, Pereira L, Van Asch B, Bradley DG, Amorim A. The mtDNA catalogue of all Portuguese autochthonous goat (Capra hircus) breeds: high diversity of female lineages at the western fringe of European distribution. Mol Ecol. 2005 Jul;14(8):2313-8. PMID: 15969716


Lynn DJ, Freeman AR, Murray CU, Bradley DG. A Genomics Approach to the Detection of Positive Selection in Cattle : Adaptive Evolution of the T Cell and NK Cell Surface Protein, CD2. Genetics 2005 Jul;170(3):1189-96. Epub 2005 Mar 31. PMID: 15802510


2004

McEvoy B, Richards M, Forster P, Bradley DG. The Longue Duree of genetic ancestry: multiple genetic marker systems and Celtic origins on the Atlantic facade of Europe. Am J Hum Genet. 2004 Oct;75(4):693-702. Epub 2004 Aug 12. PMID: 15309688


Edwards CJ, MacHugh DE, Dobney KM, Martin L, Russell N, Horwitz LK, McIntosh SK, MacDonald KC, Helmer D, Tresset A, Vigne J-D, Bradley DG. Ancient DNA analysis of 101 cattle remains: limits and prospects. Journal of Archaeological Science 31, 695-710.


Freeman AR, Meghan CM, MacHugh DE, Loftus RT, Achukwi MD, Bado A, Sauveroche B, Bradley DG. Admixture and diversity in West African cattle populations. Mol Ecol. 2004 Nov;13(11):3477-87. PMID: 15488005


Mannen H, Kohno M, Nagata Y, Tsuji S, Bradley DG, Yeo JS, Nyamsamba D, Zagdsuren Y, Yokohama M, Nomura K, Amano T. Independent mitochondrial origin and historical genetic differentiation in North Eastern Asian cattle. Mol Phylogenet Evol. 2004 Aug;32(2):539-44. PMID: 15223036


2003

Edwards CJ, Connellan J, Wallace PF, Park SD, McCormick FM, Olsaker I, Eythorsdottir E, MacHugh DE, Bailey JF, Bradley DG. Feasibility and utility of microsatellite markers in archaeological cattle remains from a Viking Age settlement in Dublin. Anim Genet. 2003 Dec;34(6):410-6. PMID: 14687070


Beja-Pereira A, Luikart G, England PR, Bradley DG, Jann OC, Bertorelle G, Chamberlain AT, Nunes TP, Metodiev S, Ferrand N, Erhardt G. Gene-culture coevolution between cattle milk protein genes and human lactase genes. Nat Genet. 2003 Dec;35(4):311-3. Epub 2003 Nov 23. PMID: 14634648


Bruford MW, Bradley DG, Luikart G. DNA markers reveal the complexity of livestock domestication. Nat Rev Genet. 2003 Nov;4(11):900-10. PMID: 14634637


Kumar P, Freeman AR, Loftus RT, Gaillard C, Fuller DQ, Bradley DG. Admixture analysis of South Asian cattle. Heredity. 2003 Jul;91(1):43-50. PMID: 12815452


2002

Magee DA, Meghen C, Harrison S, Troy CS, Cymbron T, Gaillard C, Morrow A, Maillard JC, Bradley DG. A partial African ancestry for the creole cattle populations of the Caribbean. J Hered. 2002 Nov-Dec;93(6):429-32. PMID: 12642643


Hill EW, Bradley DG, Al-Barody M, Ertugrul O, Splan RK, Zakharov I, Cunningham EP. History and integrity of thoroughbred dam lines revealed in equine mtDNA variation. Anim Genet. 2002 Aug;33(4):287-94. PMID: 12139508


Hanotte O, Bradley DG, Ochieng JW, Verjee Y, Hill EW, Rege JE. African pastoralism: genetic imprints of origins and migrations. Science. 2002 Apr 12;296(5566):336-9. PMID: 11951043


2001

Cunningham EP, Dooley JJ, Splan RK, Bradley DG. Microsatellite diversity, pedigree relatedness and the contributions of founder lineages to thoroughbred horses. Anim Genet. 2001 Dec;32(6):360-4. PMID: 11736806


Freeman AR, MacHugh DE, McKeown S, Walzer C, McConnell DJ, Bradley DG. Sequence variation in the mitochondrial DNA control region of wild African cheetahs (Acinonyx jubatus). Heredity. 2001 Mar;86(Pt 3):355-62. PMID: 11488972


MacHugh DE, Bradley DG. Livestock genetic origins: goats buck the trend. Proc Natl Acad Sci U S A. 2001 May 8;98(10):5382-4. PMID: 11344280


Troy CS, MacHugh DE, Bailey JF, Magee DA, Loftus RT, Cunningham P, Chamberlain AT, Sykes BC, Bradley DG. Genetic evidence for Near-Eastern origins of European cattle. Nature. 2001 Apr 26;410(6832):1088-91. PMID: 11323670


2000

Hill EW, Jobling MA, Bradley DG. Y-chromosome variation and Irish origins. Nature. 2000 Mar 23;404(6776):351-2. PMID: 10746711


Rosser ZH, Zerjal T, Hurles ME, Adojaan M, Alavantic D, Amorim A, Amos W, Armenteros M, Arroyo E, Barbujani G, Beckman G, Beckman L, Bertranpetit J, Bosch E, Bradley DG, Brede G, Cooper G, Corte-Real HB, de Knijff P, Decorte R, Dubrova YE, Evgrafov O, Gilissen A, Glisic S, Golge M, Hill EW, Jeziorowska A, Kalaydjieva L, Kayser M, Kivisild T, Kravchenko SA, Krumina A, Kucinskas V, Lavinha J, Livshits LA, Malaspina P, Maria S, McElreavey K, Meitinger TA, Mikelsaar AV, Mitchell RJ, Nafa K, Nicholson J, Norby S, Pandya A, Parik J, Patsalis PC, Pereira L, Peterlin B, Pielberg G, Prata MJ, Previdere C, Roewer L, Rootsi S, Rubinsztein DC, Saillard J, Santos FR, Stefanescu G, Sykes BC, Tolun A, Villems R, Tyler-Smith C, Jobling MA. Y-Chromosomal Diversity in Europe Is Clinal and Influenced Primarily by Geography, Rather than by Language. Am J Hum Genet. 2000 Dec;67(6):1526-1543. PMID: 11078479


MacHugh DE, Edwards CJ, Bailey JF, Bancroft DR, Bradley DG. The extraction and analysis of ancient DNA from bone and teeth: a survey of current methodologies. Ancient Biomolecules 2000 Oct:3, 81-102.


Edwards CJ, Dolf G, Looft C, Loftus RT, Bradley DG. Relationships between the endangered Pustertaler-Spriunzen and three related European cattle breeds as analysed with 20 microsatellite loci. Anim Genet 2000 Oct;31(5):329-332. PMID: 11105215


Helgason A, Sigureth ardottir S, Nicholson J, Sykes B, Hill EW, Bradley DG, Bosnes V, Gulcher JR, Ward R, Stefansson K. Estimating Scandinavian and Gaelic ancestry in the male settlers of Iceland. Am J Hum Genet. 2000 Sep;67(3):697-717. PMID: 10931763


Edwards CJ, Gaillard C, Bradley DG, MacHugh DE. Y-specific microsatellite polymorphisms in a range of bovid species. Anim Genet. 2000 Apr;31(2):127-30. PMID: 10782212


Hanotte O, Tawah CL, Bradley DG, Okomo M, Verjee Y, Ochieng J, Rege JE. Geographic distribution and frequency of a taurine Bos taurus and an indicine Bos indicus Y specific allele amongst sub-saharan African cattle breeds. Mol Ecol. 2000 Apr;9(4):387-96. PMID: 10736042


1999 and before

Loftus RT, MacHugh DE, Cunningham EP, Bradley DG. Animal Domestication Science 1999 283:327-330


Loftus RT, Ertugrul O, Harba AH, El-Barody MA, MacHugh DE, Park SD, Bradley DG. A microsatellite survey of cattle from a centre of origin: the Near East. Mol Ecol. 1999 Dec;8(12):2015-22. PMID: 10632853


Norris AT, Bradley DG, Cunningham EP. Microsatellite Genetic Variation between and within Farmed and Wild Atlantic Salmon (Salmo salar) populations Aquaculture 1999, 180:247-264


Nijman IJ, Bradley DG, Hanotte O, Otsen M, Lenstra JA. Satellite DNA polymorphisms and AFLP correlate with Bos indicus-taurus hybridization. Anim Genet. 1999 Aug;30(4):265-73. PMID: 10467701


Cymbron T, Loftus RT, Malheiro MI, Bradley DG. Mitochondrial sequence variation suggests an African influence in Portuguese cattle. Proc R Soc Lond B Biol Sci. 1999 Mar 22;266(1419):597-603. PMID: 10212450


MacHugh DE, Troy CS, McCormick F, Olsaker I, Eythorsdottir E, Bradley DG. Early medieval cattle remains from a Scandinavian settlement in Dublin: genetic analysis and comparison with extant breeds. Philos Trans R Soc Lond B Biol Sci. 1999 Jan 29;354(1379):99-108; discussion 108-9. PMID: 10091250


MacHugh DE, Loftus RT, Cunningham P, Bradley DG. Genetic structure of seven European cattle breeds assessed using 20 microsatellite markers. Anim Genet. 1998 Oct;29(5):333-40. PMID: 9800321


Mannen H, Tsuji S, Loftus RT, Bradley DG. Mitochondrial DNA variation and evolution of Japanese black cattle (Bos taurus). Genetics. 1998 Nov;150(3):1169-75. PMID: 9799268


Achukwi MD, Tanya VN, Hill EW, Bradley DG, Meghen C, Sauveroche B, Banser JT, Ndoki JN. Susceptibility of the Namchi and Kapsiki cattle of Cameroon to trypanosome infection. Trop Anim Health Prod Nov 1997 29(4): 219-226 PMID: 9493294


MacHugh DE, Shriver MD, Loftus RT, Cunningham P, Bradley DG. Microsatellite DNA variation and the evolution, domestication and phylogeography of taurine and zebu cattle (Bos taurus and Bos indicus). Genetics. 1997 Jul;146(3):1071-86. PMID: 9215909


Bradley DG, MacHugh DE, Cunningham P, Loftus RT. Mitochondrial diversity and the origins of African and European cattle. Proc Natl Acad Sci U S A. 1996 May 14;93(10):5131-5. PMID: 8643540


Bailey JF, Richards MB, Macaulay VA, Colson IB, James IT, Bradley DG, Hedges RE, Sykes BC. Ancient DNA suggests a recent expansion of European cattle from a diverse wild progenitor species. Proc R Soc Lond B Biol Sci 22 Nov 1996 263(1376):1467-1473 PMID: 8952089


Teale AJ, Wambugu J, Gwakisa PS, Stranzinger G, Bradley D, Kemp SJ. A polymorphism in randomly amplified DNA that differentiates the Y chromosomes of Bos indicus and Bos taurus. Anim Genet 1995 26: 243-248 PMID: 7661396


Kumar-Singh R, Bradley DG, Farrar GJ, Lawler M, Jordan SA, Humphries P. Autosomal dominant retinitis pigmentosa: a new multi-allelic marker (D3S621) genetically linked to the disease locus (RP4). Hum Genet 1995 96: 502 PMID: 7557984


Loftus RT, MacHugh DE, Bradley DG, Sharp PM, Cunningham P. Evidence for two independent domestications of cattle. Proc Natl Acad Sci U S A. 1994 Mar 29;91(7):2757-61. PMID: 8146187


Loftus RT, MacHugh DE, Ngere LO, Balain DS, Badi AM, Bradley DG, Cunningham EP. Mitochondrial genetic variation in European, African and Indian cattle populations. Anim Genet Aug 1994 25(4): 265-271 PMID: 7985843


MacHugh DE, Loftus RT, Bradley DG, Sharp PM, Cunningham P. Microsatellite DNA variation within and among European cattle breeds. Proc R Soc Lond B Biol Sci Apr 22 1994; 256(1345):25-31 PMID: 8008754


Bradley DG, MacHugh DE, Loftus RT, Sow RS, Hoste CH, Cunningham EP. Zebu-taurine variation in Y chromosomal DNA: a sensitive assay for genetic introgression in west African trypanotolerant cattle populations. Anim Genet. Feb 1994 25(1):7-12. PMID: 7909219


Kumar-Singh R, Bradley DG, Farrar GJ, Lawler M, Jordan SA, Humphries P Autosomal dominant retinitis pigmentosa: a new multi-allelic marker (D3S621) genetically linked to the disease locus (RP4). Hum Genet 1991 86: 502-504 PMID: 2016091


Farrar GJ, Kenna P, Redmond R, McWilliam P, Bradley DG, Humphries MM, Sharp EM, Inglehearn CF, Bashir R, Jay M, et al. Autosomal dominant retinitis pigmentosa: absence of the rhodopsin proline----histidine substitution (codon 23) in pedigrees from Europe. Am J Hum Genet 47: 941-945 PMID: 2239971


Farrar GJ, McWilliam P, Bradley DG, Kenna P, Lawler M, Sharp EM, Humphries MM, Eiberg H, Conneally PM, Trofatter JA, et al. Autosomal dominant retinitis pigmentosa: linkage to rhodopsin and evidence for genetic heterogeneity. Genomics 1990 8: 35-40 PMID: 2081598


Humphries MM, Sheils D, Lawler M, Farrar GJ, McWilliam P, Kenna P, Bradley DG, Sharp EM, Gaffney EF, Young M, et al. Epidermolysis bullosa: evidence for linkage to genetic markers on chromosome 1 in a family with the autosomal dominant simplex form. Genomics 1990 7: 377-381 PMID: 2365356


Bradley DG, Farrar GJ, Sharp EM, Kenna P, Humphries MM, McConnell DJ, Daiger SP, McWilliam P, Humphries P. Autosomal dominant retinitis pigmentosa: exclusion of the gene from the short arm of chromosome 1 including the region surrounding the rhesus locus. Am J Hum Genet 1989 44: 570-576 PMID: 2564733


Daiger SP, Humphries MM, Giesenschlag N, Sharp E, McWilliam P, Farrer J, Bradley D, Kenna P, McConnell DJ, Sparkes RS, et al. Linkage analysis of human chromosome 4: exclusion of autosomal dominant retinitis pigmentosa (ADRP) and detection of new linkage groups. Cytogenet Cell Genet 50: 181-187 PMID: 2572401


Farrar GJ, McWilliam P, Sharp EM, Kenna P, Bradley DG, Humphries MM, McConnell DJ, Humphries P. Autosomal dominant retinitis pigmentosa: exclusion of a gene from extensive regions of chromosomes 6, 13, 20 and 21. Genomics 5: 612-618


McWilliam P, Farrar GJ, Kenna P, Bradley DG, Humphries MM, Sharp EM, McConnell DJ, Lawler M, Sheils D, Ryan C, et al. Autosomal dominant retinitis pigmentosa (ADRP): localization of an ADRP gene to the long arm of chromosome 3. Genomics 5: 619-622



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