Professor Tríona Lally

• Flamini V, Creane A.P, Kerskens C.M, Lally C, Imaging and finite element analysis: A methodology for non-invasive characterization of aortic tissue, Medical Engineering and Physics, 37, (1), 2015, p48 - 54Journal Article, 2015, DOI , URL
• McCartney, W.T., Galvin, E., Cummins, C., Lally, C., Mac Donald, B.J., Use of a biodegradable magnesium implant for Osseous fixation in four cases, International Journal of Applied Research in Veterinary Medicine, 13, (3), 2015, p171-174Journal Article, 2015
• Zahedmanesh, H., Van Oosterwyck, H., Lally, C., A multi-scale mechanobiological model of in-stent restenosis: deciphering the role of matrix metalloproteinase and extracellular matrix changes, Computer Methods in Biomechanics and Biomedical Engineering, 17, (8), 2014, p813-828Journal Article, 2014
• Brackmann, C., Dahlberg, J.-O., Vrana, N.E., Lally, C., Gatenholm, P., Enejder, A., Non-linear microscopy of smooth muscle cells in artificial extracellular matrices made of cellulose, Journal of Biophotonics, 5, (5-6), 2012, p404-414Journal Article, 2012
• Campbell, E.M., Cahill, P.A., Lally, C., Investigation of a small-diameter decellularised artery as a potential scaffold for vascular tissue engineering; biomechanical evaluation and preliminary cell seeding, Journal of the Mechanical Behavior of Biomedical Materials, 14, 2012, p130-142Journal Article, 2012
• Redmond, E.M., Lally, C., Cahill, P.A., Hemodynamic control of vascular smooth muscle function, Muscle, 2, 2012, p1231-1242Journal Article, 2012
• Zahedmanesh, H., Lally, C., A multiscale mechanobiological modelling framework using agent-based models and finite element analysis: Application to vascular tissue engineering, Biomechanics and Modeling in Mechanobiology, 11, (3-4), 2012, p363-377Journal Article, 2012
• Guha, S., Cullen, J.P., Morrow, D., Colombo, A., Lally, C., Walls, D., Redmond, E.M., Cahill, P.A., Glycogen synthase kinase 3 beta positively regulates Notch signaling in vascular smooth muscle cells: Role in cell proliferation and survival, Basic Research in Cardiology, 106, (5), 2011, p773-785Journal Article, 2011
• Zahedmanesh, H., MacKle, J.N., Sellborn, A., Drotz, K., Bodin, A., Gatenholm, P., Lally, C., Bacterial cellulose as a potential vascular graft: Mechanical characterization and constitutive model development, Journal of Biomedical Materials Research - Part B Applied Biomaterials, 97 B, (1), 2011, p105-113Journal Article, 2011
• Colombo, A., Zahedmanesh, H., Toner, D.M., Cahill, P.A., Lally, C., A method to develop mock arteries suitable for cell seeding and in-vitro cell culture experiments, Journal of the Mechanical Behavior of Biomedical Materials, 3, (6), 2010, p470-477Journal Article, 2010
• Creane, A., Maher, E., Sultan, S., Hynes, N., Kelly, D.J., Lally, C., Patient specific finite element modelling of the carotid bifurcation, Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, (PART A), 2009, p529-530Journal Article, 2009
• Maher, E., Creane, A., Sultan, S., Hynes, N., Lally, C., Kelly, D.J., Mechanical characterization of fresh human carotid atherosclerotic plaque, Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, (PART B), 2009, p1307-1308Journal Article, 2009
• Zahedmanesh, H., Lally, C., Determination of the influence of stent strut thickness using the finite element method: Implications for vascular injury and in-stent restenosis, Medical and Biological Engineering and Computing, 47, (4), 2009, p385-393Journal Article, 2009
• Zahedmanesh, H., Gatenholm, P., Lally, C., Bacterial cellulose: A potential vascular graft and tissue engineering scaffold, Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, (PART A), 2009, p519-520Journal Article, 2009
• Flamini, V., Kerskens, C., Lally, C., An anisotropic structural model of the aortic wall based on tensile tests and non-invasive 3D fibre analysis using diffusion tensor imaging, Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, (PART A), 2009, p411-412Journal Article, 2009
• Lally, C., Sellborn, A., Bodin, A., Bäckdahl, H., Gatenholm, P., Risberg, B., Mechanical characterization of bacterial cellulose tubes for vascular tissue engineering, 8th World Biomaterials Congress 2008, 2, 2008Journal Article, 2008
• Colombo, A., Cahill, P.A., Lally, C., An analysis of the strain field in biaxial Flexcell membranes for different waveforms and frequencies, Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 222, (8), 2008, p1235-1245Journal Article, 2008
• Lally, C., Dolan, F., Prendergast, P.J., Erratum to "Cardiovascular stent design and vessel stresses: A finite element analysis". [Journal of Biomechanics 38 (2005) 1574-1581] (DOI:10.1016/j.jbiomech.2004.07.022), Journal of Biomechanics, 39, (9), 2006Journal Article, 2006
• David Nolan, Caitriona Lally, A Mechanobiological Framework for the Prediction of In-Stent Restenosis; Insights into the role of load induced damage in restenotic growth, The Virtual Physiological Human Conference, Amsterdam, 26/09/2016, edited by Alfons Hoekstra , 2016Conference Paper, 2016, TARA - Full Text
• Robert Gaul, Thomas Sinnott, Caitriona Lally, The automated characterisation of collagen fibre orientation in arteries using small angle light scattering, UK Society for Biomaterials, Belfast, Ireland, 2015Poster, 2015, TARA - Full Text
• Syed Salman Shahid, Christian Kerskens, Robert Gaul, Vittoria Flamini, Caitriona Lally, Ex-vivo arterial collagen fibre tractography using micro-diffusion tensor imaging, European Society for Magnetic Resonance in Medicine and Biology , Vienna, Austria, 29-09-2017, 2016Poster, 2016, TARA - Full Text
• Shahid, Syed Salman, Christian, Kerskens, Caitriona, Lally, Use of high-resolution micro-diffusion tensor imaging to estimate the ultra-structure of the arterial wall, Bioengineering in Ireland, Belfast, 20-10-2017, 2017Oral Presentation, 2017, TARA - Full Text
• Syed salman Shahid, Christian Kerskens, Robert Gaul, Caitriona Lally, Quantification of extracellular matrix components in arterial tissue using high-resolution micro diffusion tensor imaging, European Molecular Imaging Meeting, Germany, 5-04-2017, 2017Poster, 2017, TARA - Full Text
• David R. Nolan, Caitríona Lally, An Investigation of Damage Mechanisms in Mechanobiological Models of In-Stent Restenosis, Journal of Computational Science, 2017Journal Article, 2017, URL , TARA - Full Text
• David Nolan; Caitríona Lally, An in-silico investigation into the influence of endothelial denudation on the progression on in-stent restenosis, European Society of Biomechanics, Seville, 2017Meeting Abstract, 2017, TARA - Full Text
• David Nolan, Assessment of a Clinically Relevant Geometric Measure for Identifying Vulnerable Carotid Plaques, Bioengineering in Ireland, Belfast, 2017Meeting Abstract, 2017, TARA - Full Text
• Robert Gaul, Caitriona Lally, Strain Mediated Enzyme Degradation of Arterial Tissue; Implications in Disease and Medical Device Design, Summer Biomechanics, Bioengineering and Biotransport Conference 2017, Arizona, USA, June 2017, 2017Oral Presentation, 2017, TARA - Full Text
• Robert Gaul, David Nolan, Caitriona Lally, Collagen fibre characterisation in arterial tissue under load using SALS, Journal of the Mechanical Behavior of Biomedical Materials, 75, 2017, p359 - 368Journal Article, 2017, URL , TARA - Full Text
• Syed Salman Shahid, Robert Gaul, Christian Kerskens, Vittoria Flamini, Caitriona Lally, Quantifying the ultrastructure of carotid artery using high-resolution micro-diffusion tensor imaging - Comparison of intact vs. open cut tissue , Physics in Medicine and Biology, 62, (23), 2017, p8850 - 8868Journal Article, 2017, URL , TARA - Full Text
• Coupled Finite Element-Agent Based Models for the Simulation of Vascular Growth and Remodeling in, editor(s)Miguel Cerrolaza Sandra J. Shefelbine Diego Garzon-Alvarado , Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes, Elsevier, 2017, pp283 - 298, [David Nolan, Caitriona Lally]Book Chapter, 2017
• Lally, C, Reid, AJ, Prendergast, PJ, Elastic behaviour of porcine coronary arteries under uniaxial and equibiaxial tension, Annals of Biomedical Engineering, 32, 2004, p1355 - 1364Journal Article, 2004
• Robert Gaul, David Nolan, Tomasso Ristori, Carlijn Bouten, Sandra Loerakker, Caitriona Lally, Strain Mediated Arterial Degradation is Critically Influenced by Matrix Content and Collagen Crimp, Proceedings of the 24th Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland, Meath, Ireland, 2018Oral Presentation, 2018, TARA - Full Text
• Milad Ghasemi, David Nolan, Caitríona Lally , An investigation into the role of different constituents in damage accumulation in arterial tissue and constitutive model development, Biomechanics and Modeling in Mechanobiology, 2018Journal Article, 2018, DOI , URL , TARA - Full Text
• Robert Gaul, David Nolan, Tomasso Ristori, Carlijn Bouten, Sandra Loerakker, Caitriona Lally, Strain mediated Enzymatic Degradation of arterial tissue: Insights into the role of the non-collagenous tissue matrix and collagen crimp, Acta Biomaterialia, 2018Journal Article, 2018, DOI , TARA - Full Text
• Robert Gaul, David Nolan, Tomasso Ristori, Carlijn Bouten, Sandra Loerakker, Caitriona Lally, Degradation of arterial collagen with applied strain: critical influence of matrix content and collagen crimp, 8th World Congress of Biomechanics, Dublin, Ireland, 8-12 July, 2018Oral Presentation, 2018, TARA - Full Text
• Robert Gaul, David Nolan, Caitríona Lally, The use of small angle light scattering in assessing strain induced collagen degradation in arterial tissue ex vivo , Journal of Biomechanics, 2018Journal Article, 2018, TARA - Full Text
• Alix Whelan, Collagen fibre orientation and dispersion govern ultimate tensile strength, stiffness and the fatigue performance of bovine pericardium, Journal of the Mechanical Behavior of Biomedical Materials, 90, 2019, p54 - 60Journal Article, 2019, DOI , TARA - Full Text
• Clarkin O.M., Wu B., Cahill P.A., Brougham D.F., Banerjee D., Brady S.A., Fox E.K., Lally C., Novel injectable gallium-based self-setting glass-alginate hydrogel composite for cardiovascular tissue engineering, Carbohydrate Polymers, 217, 2019, p152 - 159, p152-159Journal Article, 2019, DOI
• Schipani, R. and Nolan, D.R. and Lally, C. and Kelly, D.J., Integrating finite element modelling and 3D printing to engineer biomimetic polymeric scaffolds for tissue engineering, Connective Tissue Research, 2019Journal Article, 2019, DOI , URL , TARA - Full Text
• Ghasemi M., Nolan D.R., Lally C., Assessment of mechanical indicators of carotid plaque vulnerability: Geometrical curvature metric, plaque stresses and damage in tissue fibres, Journal of the Mechanical Behavior of Biomedical Materials, 103, 2020Journal Article, 2020, DOI
• Mathieu P.S., Fitzpatrick E., Di Luca M., Cahill P.A., Lally C., Resident multipotent vascular stem cells exhibit amplitude dependent strain avoidance similar to that of vascular smooth muscle cells, Biochemical and Biophysical Research Communications, 521, (3), 2020, p762 - 768, p762-768Journal Article, 2020, DOI
• Alix Whelan, Elizabeth Williams, David Nolan, Bruce Murphy, Paul Gunning, David O'Reilly, Caitríona Lally, Bovine pericardium of high fibre dispersion has high fatigue life and increased collagen content; potentially an untapped source of heart valve leaflet tissue , Annals of Biomedical Engineering, 2020Journal Article, 2020, TARA - Full Text
• Brooke Tornifoglio, Alan J. Stone, Robert D. Johnston, Salmon S. Shahid, Christian Kerskens, Caitriona Lally, Diffusion tensor imaging and arterial tissue: establishing the influence of arterial tissue microstructure on fractional anisotropy, mean diffusivity and tractography, Scientific Reports, 2020Journal Article, 2020, TARA - Full Text
• Tornifoglio B., Johnston R.D., Stone A.J., Kerskens C., Lally C., Microstructural and mechanical insight into atherosclerotic plaques: an ex vivo DTI study to better assess plaque vulnerability, Biomechanics and Modeling in Mechanobiology, 2023Journal Article, 2023, TARA - Full Text
• Tornifoglio B., Stone A.J., Kerskens C., Lally C., Ex Vivo Study Using Diffusion Tensor Imaging to Identify Biomarkers of Atherosclerotic Disease in Human Cadaveric Carotid Arteries, Arteriosclerosis, Thrombosis, and Vascular Biology, 42, (11), 2022, p1398 - 1412, p1398-1412Journal Article, 2022, DOI , TARA - Full Text
• Johnston, Robert D., Ghasemi, Milad, Lally, Caitríona, Inverse material parameter estimation of patient"specific finite element models at the carotid bifurcation: The impact of excluding the zero"pressure configuration and residual stress, International Journal for Numerical Methods in Biomedical Engineering, 39, (1), 2023Journal Article, 2023, DOI , TARA - Full Text
• Lally, C, Dolan, F, Prendergast, PJ, Cardiovascular stent design and blood vessel stress: a finite element analysis, Journal of Biomechanics, 38, (8), 2005, p1574 - 1581Journal Article, 2005, DOI , URL
• Prendergast, PJ, Lally, C, Daly, S, Lee, TC, Quinn, D, Dolan, F, Analysis of prolapse in cardiovascular stents: a constitutive equation for vascular tissue and finite element modelling, Journal of Biomechanical Engineering , 125, 2003, p692-699Journal Article, 2003
• Pericevic, I., Lally, C., Toner, D., Kelly, D.J. , The influence of plaque composition on underlying arterial wall stress during stent expansion: the case for lesion-specific stents, Medical Engineering and Physics , 31, (4), 2009, p428-433Journal Article, 2009, DOI , URL , TARA - Full Text
• Vittoria Flamini, Christian Kerskens, Kevin Mattheus Moerman, Ciaran Simms and Caitríona Lally , Imaging Arterial Fibres Using Diffusion Tensor Imaging-Feasibility Study and Preliminary Results, EURASIP Journal on Advances in Signal Processing, 2010, (904091), 2010Journal Article, 2010, DOI , URL , TARA - Full Text
• Maher, E., Creane, A., Sultan, S., Hynes, N., Lally, C. Kelly, D.J. , Tensile and compressive properties of fresh human carotid atherosclerotic plaques. , Journal of Biomechanics, 42, (16), 2009, p2760-2767Journal Article, 2009, DOI , TARA - Full Text
• Moerman, KM ; Kerskens, CM ; Lally, C ; Flamini, V ; Simms, CK , Evaluation of a Validation Method for MR Imaging-Based Motion Tracking Using Image Simulation, EURASIP Journal on Advances in Signal Processing, 2010, 2010, p942131Journal Article, 2010, DOI , TARA - Full Text
• Michael Early; Catriona Lally; Patrick J. Prendergast; Daniel J. Kelly, Stresses in peripheral arteries following stent placement: a finite element analysis, Computer Methods in Biomechanics and Biomedical Engineering, 12, (1), 2009, p25 - 33Journal Article, 2009, DOI , URL , TARA - Full Text
• Boyle CJ, Lennon AB, Early M, Kelly DJ, Lally C, Prendergast PJ, Computational simulation methodologies for mechanobiological modelling: a cell-centred approach to neointima development in stents., Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 368, (1921), 2010, p2919-35Journal Article, 2010, DOI , URL , TARA - Full Text
• Flamini V, Kerskens C, Moerman K, Simms C and Lally C, Imaging arterial fibres using diffusion tensor imaging - feasibility study & preliminary results, EURASIP Journal on Advances in Signal Processing, 2010, 2010, pArticle ID 904091Journal Article, 2010, DOI , TARA - Full Text
• Boyle, C.J., Lally, C., Prendergast, P.J, Injury driven biological model of restenotic lesion development predicts the effects of stent geometry on restenosis, Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, 11th ASME Summer Bioengineering Conference, SBC2009, Lake Tahoe, edited by 17-21 June , PART B, ASME, 2009, pp1055-1056Conference Paper, 2009
• Maher, E., Creane, A., Sultan, S., Hynes, N., Lally, C. Kelly, D.J., Inelasticity of Human Carotid Atherosclerotic Plaque. , Annals of Biomedical Engineering, 39, (9), 2011, p2445-2455Journal Article, 2011, DOI
• Creane, A., Maher, E., Sultan, S., Hynes, N., Kelly, D.J., Lally, C. Nagel, T., Kelly, D.J., Prediction of fibre architecture and adaptation in diseased carotid bifurcations. , Biomechanics and Modeling in Mechanobiology , 10, (6), 2011, p831-843Journal Article, 2011, DOI
• Zahedmanesh, H., Kelly, D.J., Lally, C. , Simulation of a balloon expandable stent in a realistic coronary artery; Determination of the optimum modelling strategy, Journal of Biomechanics, 43, (11), 2010, p2126-2132Journal Article, 2010, DOI
• Creane, A., Maher, E., Sultan, S., Hynes, N., Kelly, D.J., Lally, C. , Finite element modelling of diseased carotid bifurcations generated from in vivo computerised tomographic angiography., Computers in Biology and Medicine, 40, (4), 2010, p419-429Journal Article, 2010, DOI
• Eoghan Maher, Arthur Creane, Caitríona Lally, Daniel J. Kelly, An anisotropic inelastic constitutive model to describe stress softening and permanent deformation in arterial tissue, Journal of the Mechanical Behavior of Biomedical Materials, 12, 2012, p9-19Journal Article, 2012, DOI , URL , TARA - Full Text
• Maher E, Early M, Creane A, Lally C, Kelly DJ, Site specific inelasticity of arterial tissue., Journal of biomechanics, 45, (8), 2012, p1393-1399Journal Article, 2012, DOI , TARA - Full Text
• Creane, A., Maher, E., Sultan, S., Hynes, N., Kelly, D.J., Lally, C., A remodelling metric for angular fibre distributions and its application to diseased carotid bifurcations., Biomechanics and Modeling in Mechanobiology, 11, (6), 2012, p869-882Journal Article, 2012, DOI
• Flamini V, Kerskens C, Moerman K, Simms CK and Lally C, Fibre orientation of fresh and frozen porcine aorta determined non-invasively, Medical Engineering and Physics, 35, (6), 2013, 765-776Journal Article, 2013, DOI
• Patient Specific Computational Modeling in Cardiovascular Mechanics in, Patient-Specific Computational Modeling, 2012, pp61-79 , [A Creane, DJ Kelly, C Lally. ]Book Chapter, 2012, DOI
• Colombo, A., Guha, S., Mackle, J.N., Cahill, P.A., Lally, C., Cyclic strain amplitude dictates the growth response of vascular smooth muscle cells in vitro: Role in in-stent restenosis and inhibition with a sirolimus drug-eluting stent, Biomechanics and Modeling in Mechanobiology, 12, (4), 2013, p671-683Journal Article, 2013, DOI
• Galvin, E., Morshed, M.M., Cummins, C., Daniels, S., Lally, C., MacDonald, B., Surface modification of absorbable magnesium stents by reactive ion etching, Plasma Chemistry and Plasma Processing, 33, (6), 2013, p1137-1152Journal Article, 2013, DOI

• Robert Gaul, Caitriona Lally, Strain mediated enzyme degradation of arterial tissue characterised by small angle light scattering, Proceedings of the 23rd Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland., Belfast, Ireland, 2017Oral Presentation, TARA - Full Text
• Robert Gaul, Caitriona Lally, Load induced changes in collagen fibre architecture in arteries characterised by small angle light scattering, Proceedings of the 22nd Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland, Galway, Ireland, 2016Oral Presentation, TARA - Full Text
• Robert Gaul, Caitriona Lally, The use of small angle light scattering for the characterisation of collagen fibre orientation in arteries, Proceedings of the 21st Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland, Kildare, Ireland, 2015Oral Presentation, TARA - Full Text
• Alix Whelan, Robert Gaul, Paul Gunning, Caitriona Lally, Investigation of Collagen Fibre Orientation in Bovine Pericardium, Proceedings of the 23rd Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland, Belfast, 20/01/17, 2017Oral Presentation, TARA - Full Text
• Simulation of in-stent restenosis for the design of cardiovascular stents in, G. Holzpafel & R. Ogden , Mechanics of Biological Tissue, Springer, 2006, pp255 - 267, [Lally, C, Prendergast, PJ]Book Chapter

Materials Science, Medical Engineering, Biotechnology and devices (including medical laboratory technologies and informatics), Cardiovascular& Related Disease, Medical Engineering, Biotechnology and devices (including medical laboratory technologies and informatics), Cardiovascular& Related Disease, Materials Science,

• Career Start Grant (DCU) 2005
• Royal Society of Medicine in Ireland, 1st prize for best student paper 2004
• Senior author on research paper which was awarded 2nd prize for the Engineers Ireland - IMECHE Young Engineers Research Award 2012
• Royal Society of Medicine in Ireland, 2nd prize for best student paper 2002
• ERC Starting Grant 2014
• Bernard Crossland Symposium, 2nd prize for best student paper 2002
• Sylvestor O'Halloran Surgical Meeting, 1st prize in poster presentation 2002

• Member of the Institution of Engineers of Ireland (MIEI) and member of the committee for the Biomedical Division of the IEI (2006-2009) Member of the Royal Academy of Medicine of Ireland (RAMI) and the European Society of Biomechanics. PI in the Trinity Centre for Bioengineering

• Research Committee Member
• Research Committee Member