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Dr. Lucy Norris
SENIOR EXP OFFICER OBS&GYN (P/T 17/8/06), Obstetrics

Biography

Lucy Norris MSc Mol. Med. PhD https://orcid.org/0000-0001-7862-3230. Lucy Norris graduated from Trinity College Dublin with an honours degree in Biochemistry. She was awarded a PhD in 1992 from TCD Dept of Obstetrics and Gynaecology based on her work investigating platelet activation in pregnancy, pre-eclampsia and oral contraception. She is the Principal Investigator of Coagulation Research group at the Department of obstetrics and Gynaecology and has over 25 years' experience in the area of haemostasis and thrombosis research. Her current research program focuses on the prediction of venous thrombosis in gynaecological cancer and the role of coagulation gene expression in the aetiology of ovarian cancer and has received independent funding from the HRB and the pharmaceutical industry. She has over 100 peer reviewed articles many as senior author(h-index:24, i10 index 41, Citations 2188). She is co-editor in chief of the journal "Thrombosis Update" and a member of the editorial board of Thrombosis Research and European Journal of Gynaecological Oncology.

Publications and Further Research Outputs

Peer-Reviewed Publications

O'Neill AM, Calpin GG, Norris L, Beirne JP., The impact of enhanced recovery after gynaecological surgery: A systematic review and meta-analysis. , Gynaecological Oncology, 168, 2023, p8 - 16 Journal Article, 2023 URL

Lucy A Norris, Feras Abu Saadeh, "Risk of venous thromboembolism and bleeding after major surgery for ovarian cancer: standard in-hospital versus extended duration of thromboprophylaxis": Comment . , Journal of Thrombosis and Haemostasis, 21, (6), 2023, p1681 - 1683 Journal Article, 2023

Mohamed BM, Ward MP, Bates M, Spillane CD, Kelly T, Martin C, Gallagher M, Heffernan S, Norris L, Kennedy J, Saadeh FA, Gleeson N, Brooks DA, Brooks RD, Selemidis S, O'Toole S, O'Leary JJ., Ex vivo expansion of circulating tumour cells (CTCs)., Scientific reports, 13, (1), 2023, p3704 - 3704 Journal Article, 2023 DOI

Mark P Ward, Mark Bates, Bashir Mohamed, Tanya Kelly, Roisin O'Connor, Robert Brooks, Doug Brooks, Stavros Selemidis, Celine Ovaere, Jane Tully, Patrick Maguire, Catherine O'Gorman, Waseem Kamran, James Beirne, Feras Saadeh, Noreen Gleeson, Lucy Norris, Cara Martin, Sharon O'Toole, John O'Leary, Isolation and characterisation of circulating tumour cells from ovarian cancer patients, LABORATORY INVESTIGATION, March 2022, 102, (SUPPL 1), SPRINGER NATURE, 2022 Poster, 2022 DOI

Ward MP, O'Toole SA, Abu Saadeh F, Marchocki Z, Ibrahim EM, Martin F, Gleeon N, O'leary JJ, Norris LA, Mechanisms of cancer associated thrombosis in gynaecological cancer patients- tumour or treatment effect?, Research Practice in Thrombosis and Haemostasis, International Society for Thrombosis and Haemostasis, London, July 2022, 6, (Supplement 2), Wiley, 2022, ppPB0752 - PB0752 Conference Paper, 2022 URL

Batog, WI, Maguire P, O'Toole SA, Norris L, Abu Saadeh F, Identification of groin node metastasis in squamous vulval cancer using pre-operative [18F] FDG-PET/CT. Can unnecessary lymphadectomy be prevented?, International Journal of Gynaecological Cancer, European Society for Gynaecological Oncology, Berlin, October 2022, 32, (Supplement 2), 2022, pp1590 - 1590 Conference Paper, 2022 URL

Ward MP, Lochrin SE, Ovarere C, O'Gorman C, Kane LE, Mohamed BM, Bates M, Kelly TE, O'Connor R, Kennedy J, Cadoo K, Kamran W, Beirne J, Abu Saadeh F, Martin CM, Norris LA, O'Toole SA, O'leary JJ, Platelets and immune call cloaking of circulating tumour cells in breast and ovarian cancer, Research Practice in Thrombosis and Haemostasis, International Society for Thrombosis and Haemostasis, London, July 2022, 6, ((supplement 2)), Wiley, 2022, ppPB0931 - PB0931 Conference Paper, 2022 URL

Elzahra Ibrahim, Lucy Norris, Feras Abu Saadeh, Does the use of long-term Aspirin reduce risk of post operative VTE in Gynaecological cancer patients, International Journal of Gynecologic Cancer, 23rd ESGO, Berlin, Oct 2022, 32, 2022 Poster, 2022 URL

Ward MP, Ibrahim E, O'Toole S, Gleeson N, Abu Saadeh F, O'Donnell D, Norris LA, Thrombomodulin as a marker for VTE following neoadjuvant chemotherapy, Thrombosis Research, International Congress on Issues in Thrombosis in Cancer , Bergamo, Italy, May 2022, 213, ((6) Supplement 2), Elsevier, 2022, ppS13 - S14 Conference Paper, 2022 URL

Ibrahim, Elzahra, Norris, Lucy A., Abu Saadeh, Feras, Update on extended prophylaxis for venous thromboembolism following surgery for gynaecological cancers, Thrombosis Update, 2, 2021, p100038 Journal Article, 2021 DOI

Spillane CD, Cooke NM, Ward MP, Kenny D, Blackshields G, Kelly T, Bates M, Huang Y, Martin C, Skehan S, Canney A, Gallagher M, Smyth P, Brady N, Clarke A, Mohamed B, Norris L, Brooks DA, Brooks RD, Heatlie JK, Selemidis S, Hanniffy S, Dixon E, Sheils O, O'Toole SA, O'Leary JJ., The induction of a mesenchymal phenotype by platelet cloaking of cancer cells is a universal phenomenon., Translational oncology, 14, (12), 2021, p101229 Journal Article, 2021 DOI

O'Toole SA, Huang Y, Norris L, Power Foley M, Shireen R, McDonald S, Kamran W, Ibrahim N, Ward M, Thompson C, Murphy C, D'Arcy T, Farah N, Heron E, O'Leary JJ, Abu Saadeh F, Gleeson N., HE4 and CA125 as preoperative risk stratifiers for lymph node metastasis in endometrioid carcinoma of the endometrium: A retrospective study in a cohort with histological proof of lymph node status., Gynecologic oncology, 2021 Journal Article, 2021 DOI

Papadakis E and Norris LA, Covid-19: "the end of the beginning", 1826, 2021, - Miscellaneous, 2021 DOI

Abu Saadeh F, Marchocki Z, O'Toole SA, Ibrahim N, Gleeson N, Norris LA., Extended thromboprophylaxis post gynaecological cancer surgery; the effect of weight adjusted and fixed dose LMWH (Tinzaparin)., Thrombosis Research, 207, 2021, p25 - 32 Journal Article, 2021 DOI

E Ibrahim, SA O'Toole, F Abu Saadeh, LA Norris., Lymph node status as a predictor of venous thromboembolic risk postoperatively in gynae-oncology. , International Journal of Gynecologic Cancer, European Society For Gynae-Oncology (ESGO), 31, (Supplement 3), 2021 Conference Paper, 2021

McKendry, Kate, Duff, Stephen, Huang, Yanmei, Redha, Mostafa, Scanlon, Áine, Abu Saadeh, Feras, Gleeson, Noreen, O"Leary, John, Norris, Lucy, O"Toole, Sharon, The value of HE4, D"dimer, and fibrinogen compared to CA125 alone in triaging women presenting with pelvic masses: a retrospective cohort study, Acta Obstetricia et Gynecologica Scandinavica, 2021 Journal Article, 2021 DOI

Ward, Mark P., Saadeh, Feras Abu, O'Toole, Sharon A., O'Leary, John J., Gleeson, Noreen, Norris, Lucy A., Procoagulant activity in high grade serous ovarian cancer patients following neoadjuvant chemotherapy-The role of the activated protein C pathway, Thrombosis Research, 200, 2021, p91 - 98 Journal Article, 2021 DOI

Ibrahim E, O'Toole S, Ward M, Abu Saadeh F, Norris LA. , Factor VIIIc predicts venous thromboembolism in gynaecological cancer patients., Research. Practice in Thrombosis. and Haemostasis , International Society for Thrombosis and Haemostasis, Philadelphia, July 2021, 5, (Supplement 2), Wiley, 2021, ppPB1096 - PB1096 Conference Paper, 2021 URL

Ward, M.P., Kane, L.E., Norris, L.A et al. , Platelets, immune cells and the coagulation cascade; friend or foe of the circulating tumour cell?, Molecular Cancer, 20, 2021, p59- Journal Article, 2021 DOI

European Journal of Gynaecological cancer, Elsevier, [eds.], 2020-2030 Editorial Board, 2020

Norris LA, Ward MP, O'Toole SA, Marchocki Z, Ibrahim N, Khashan AS, Abu Saadeh F, Gleeson N. , A risk score for prediction of venous thromboembolism in gynecologic cancer: The Thrombogyn score. , Research Practice in Thrombosis and Haemostasis, 4, (5), 2020, p848 - 859 Journal Article, 2020 DOI

Norris, Lucy A., Papadakis, Emmanouil S., A new journal in a brave new world, 1826, 2020, - Miscellaneous, 2020 DOI

Thrombosis Update, (2020), Lucy Norris, [eds.] Journal, 2020

S O'Toole, M Foley, S Rizmee, L Norris, W Kamran, N Ibrahim, M Ward, C Thompson, C Murphy, M Anglim, T D'Arcy, N Farah, H O'Connor, J O'Leary, F AbuSaadeh, N Gleeson, HE4 has a role in identifying high risk prognostic factors in endometrial cancer, International Journal of Gynaecological Cancer, 29, ((Supplement 4)), 2019, ppA351 - A352 Published Abstract, 2019

Marchocki Z, Norris L, O'Toole S, Gleeson N, Abu Saadeh F, Patients' experience and compliance with extended low molecular weight heparin prophylaxis post-surgery for gynaecological cancer. A prospective observational study, International Journal of Gynaecological Cancer. , 2019 Journal Article, 2019 DOI

Eilis Perez, Bashir Mohamed, Danny Di Capua, Noreen Gleeson, Claire Thompson, Feras Abu Saadeh, Cara Martin, Lucy Norris, Ciaran O'Riain, Mark Bates, Lorraine O'Driscoll, John O'Leary, Sharon O'Toole. , High Expression Of Neuromedin U In High Grade Serous Ovarian Cancer Confers A Progression Free Survival Advantage., Laboratory Investigation, 99, 2019, pp101 - 101 Published Abstract, 2019

Marchocki Z, Norris LA, , Abu Saadeh F, Gleeson N, Recurrence of Venous thromboembolism in gynaecological malignancies, incidence, risk factors and impact on survival, European Journal of Gynae Oncology , 40, (3), 2019, p413 - 419 Journal Article, 2019 DOI

O'Toole S, Melarcode H, Elbaruni S, F AbuSaadeh, M Ward, M Gallagher, L Norris, S Gray, J O`Leary and B Mohamed., EP926 PAD enzymes as a candidate therapeutic target in ovarian cancer, International Journal of Gynaecological Cancer, 29, ((Supplement 4)), 2019, ppA497 - A497 Published Abstract, 2019

B Mohamed, S O'Toole, S Elbaruni, L Norris, F AbuSaadeh, S Gray, J. O'Leary , EP926 PAD enzymes as a candidate therapeutic target in ovarian cancer, International Journal of Gynaecological Cancer, 29, ((Supplement 4)), 2019, ppA497 - A497 Published Abstract, 2019

Melad Saed, Sharon O'Toole, Lucy Norris, Steven Gray, Feras Abu Saadeh, John O'Leary, Bashir Mohamed. , The Efficacy Of Nanocomplexes Complexed With Specific Biomarker Targets In Ovarian Cancer Treatment, An Ex-Vivo Explant Case Study, Laboratory Investigation, 99, 2019, pp106 - 106 Published Abstract, 2019

Thrombosis Update, Elsevier, [Editor in Chief], 2019-2029 Editorial Board, 2019

Z. Marchocki, N. Gleeson, F. Abu Saadeh, M.P. Ward, S.A. O'Toole, L.A. Norris, Fibrinogen, D-Dimers and thrombin generation assays as predictors of the risk of recurrent VTE in patients with gynaecological malignancies, Thrombosis Research, International Congress on Thrombosis and Haemostasis Issues in Cancer, Bergamo, April 2018, 164, (Supplement 1), 2018, pp200 - 200 Meeting Abstract, 2018 DOI

Ward MP, Abu Saadeh, F, O'Toole S, Marchocki Z, Gleeson N, Norris LA, Optimisation of Thrombin Generation as a Predictive Biomarker for Venous Thromboembolism in Gynaecological Malignancies, Research Practice in Thrombosis and Haemostasis, International Society for Thrombosis and Haemostasis, Dublin, July 2018, 2, (Supplement 1), Wiley, 2018, ppPB518 - PB518 Published Abstract, 2018 DOI

LA Norris, F Abu Saadeh, M Ward, SA O'Toole, Z Marchocki, N. Ibrahim, N Gleeson, Development and validation of a risk model for prediction of venous thromboembolism in gynaecological cancer patients, Thrombosis Research, International Congress on Thrombosis and Haemostasis Issues in Cancer, Bergamo, April 2018, 164, (Supplement 1), Elsevier, 2018, ppS183 - S184 Oral Presentation, 2018 DOI

Thompson C, McCormick C, Kamran W, O'Riain C, Norris L, Gallagher D, Gleeson N., Risk reduction surgery (RRS) for tubo-ovarian cancer in an Irish gynaecological practice: an analysis of indications and outcomes, Irish Journal of Medical Science, 2018 Journal Article, 2018 DOI

Z. Marchocki, L.N. Norris, S.A. O'Toole, N. Gleeson, F. Abu Saadeh S235, Patients experience and compliance with extended LMWH prophylaxis post-surgery for gynaecological cancer, Thrombosis Research, International Congress on Thrombosis and Haemostasis Issues in Cancer, Bergamo, April 2018, 164, (Supplement 1), Elsevier, 2018, ppS235 - S235 Published Abstract, 2018 DOI

Thompson C, Kamran W, Dockrell L, Khalid S, Kumari M, Ibrahim N, OʼLeary J, Norris L, Petzold M, OʼToole S, Gleeson N, The Clearance of Serum Human Epididymis Protein 4 Following Primary Cytoreductive Surgery for Ovarian Carcinoma, International Journal of Gynaecological Cancer, 28, (6), 2018, p1066 - 1072 Journal Article, 2018 DOI

M.P. Ward, F.A. Saadeh, J.J. O'Leary, N. Gleeson, S.A. O'Toole, L.A. Norris ., The Effect of Neoadjuvant Chemotherapy on the Activated Protein C (aPC) Pathway in High Grade Serous Ovarian Cancer Patients., Research Practice in Thrombosis and Haemostasis, International Society for Thrombosis and Haemostasis , Berlin, July 2017, 1, (1), Wiley, 2017, pp625 - 625 Published Abstract, 2017 DOI

Marchocki Z, Abu Saadeh F, Gleeson N, Norris L, Risk of recurrence of venous thromboembolism in patients with gynaecological cancer, Thrombosis Research, Womens Issues in Thrombosis and Haemostasis, Barcelona, March 2017, 151, (Supplement 1), 2017, ppS133 - S133 Published Abstract, 2017 DOI

C. Spourquet, M.P. Ward, F.A. Saadeh, J.J. O'Leary, N. Gleeson, S.A. O'Toole, L.A. Norris., Expression of Coagulation Proteases from the Activated Protein C Pathway in Ovarian Tumours, Research Practice in Thrombosis and Haemostasis , ISTH, Berlin, July 2017, 1, (1), Wiley, 2017, pp630 - 630 Published Abstract, 2017 DOI

Martin F, Long JC, O'Toole SA, O'Leary JJ, Abu Saadeh F, Gleeson N, Norris LA, Tumour expression of coagulation proteases of the aPC pathway - a role in the pathogenesis of gynaecological cancers?, Thrombosis Research, International Congress on Thrombosis and Haemostasis Issues in Cancer, Bergamo, April 2016, 140, (Supplement 1), 2016, ppS181 - S181 Published Abstract, 2016 DOI

Abu Saadeh, F, Langhe R, Galvin DM, O Toole SA, O'Donnell DM, Gleeson N, Norris LA, Procoagulant activity in gynaecological cancer patients; the effect of surgery and chemotherapy. , Thrombosis Research, 139, 2016, p135 - 141 Journal Article, 2016 DOI

Petch S, Norris LA, O'Toole SA, Gleeson N, Saadeh FA, OC-12 - Peri operative venous thromboembolism prophylaxis in gynaecological cancer patients. A survey of current practice., 2016 Journal Article, 2016

Norris LA, Martin FA, O'Toole SA, Saadeh FA, Gleeson N, PO-24 - Determinants of thrombin generation in gynaecological malignancies., 2016 Published Abstract, 2016 DOI

Petch S, Norris L, O'Toole S, Gleeson N, Abu Saadeh F., Peri operative venous thromboembolism prophylaxis in gynaecological cancer patients. A survey of current practice, Thrombosis Research, 145, 2016, p126 - 128 Journal Article, 2016 DOI

Ismail SK, Norris L, Higgins JR, Thrombin generation assays for optimizing low molecular weight heparin dosing in pregnant women at risk of thrombosis, British Journal of Haematology, 2015, pdoi: 10.1111/bjh.13521. Journal Article, 2015 URL

Langhe R, Norris L, Saadeh FA, Blackshields G, Varley R, Harrison A, Gleeson N, Spillane C, Martin C, O'Donnell DM, D'Arcy T, O'Leary J, O'Toole S, A novel serum microRNA panel to discriminate benign from malignant ovarian disease, Cancer Letters, 356, ((2ptB)), 2015, p628-636- Journal Article, 2015 DOI

Siti K. Ismail, Lucy Norris, Ali Khashan, Nigel Simpson, Gustaaf Dekker, Jenny Myers, Lesley McCowan, Louise Kenny, John R. Higgins, [174-POS], Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 5, (1), 2015, p89--90 Journal Article, 2015

Ismail SK, Norris L, O'Shea S, Higgins JR, Weight-adjusted LMWH Prophylaxis Provides More Effective Thrombin Inhibition in Morbidly Obese Pregnant Women, Thrombosis Research, 134, (2), 2014, p234 - 239 Journal Article, 2014 DOI

Ibrahim N, Norris L, Nikolov N, Gleeson N, Thromboelastography as a tool for detecting hypercoagulability in gynaecological cancer patients undergoing surgery, Thrombosis Research, 7th International Conference on Thrombosis & Hemostatis Issues in Cancer,, Bergamo Italy, May 2014, edited by A Falanga, B. Brenner, F, Rickles , 133, (Suppl 2), Elsevier, 2014 Published Abstract, 2014

Ibrahim N, Norris L, O'Toole S, Gleeson N, The effect of LMWH (tinzaparin) post surgery in gynaecological patients: a study of ant-Xa activity levels., Thrombosis Research, 7th Internation Conference on Thrombosis & Hemostatis Issues in Cancer,, Bergamo Italy, May 2014, edited by A Falanga, B. Brenner, F, Rickles , 133, (Suppl 2), Elsevier, 2014, pps204- Published Abstract, 2014

Abu Saadeh F, O'Toole S, Gleeson N, Norris L, Peak ant-Xa levels following LMWH (tinzaparin) prophylaxis in gynaecological cancer patients post surgery, Thrombosis Research, 7th Internation Conference on Thrombosis & Hemostatis Issues in Cancer, , Bergamot Italy, May 2014, edited by A Falanga, B. Brenner, F, Rickles , 133, (Suppl 2), Elsevier, 2014 Published Abstract, 2014

Kelly LA, Seidlova-Wuttke D, Wuttke W, O'Leary JJ, Norris LA, Estrogen receptor alpha augments changes in hemostatic gene expression in HepG2 cells treated with estradiol and phytoestrogens. , Phytomedicine , 21, (2), 2014, p155 - 158 Journal Article, 2014 URL

Abu Saadeh, Norris L, O'Toole S, Mohamed BM, Langhe R, O'Leary J, Gleeson N, Tumour expresion of tissue factor and tissue factor pathway inhibitor in ovarian cancer- relationship with venous thrombosis risk., Thrombosis Research, 132, 2013, p627 - 634 Journal Article, 2013 DOI

Brosnan JF, Sheppard BL, Kelly LA, O'Leary JJ, Norris LA, Norethisterone acetate alters coagulation gene expression in vitro in human cell culture., Thrombosis research, 131, (1), 2013, p72 - 77 Journal Article, 2013 DOI

Abu Saadeh F, Norris L, O'Toole S, Gleeson N, Venous thromboembolism in ovarian cancer: Incidence, risk factors and impact on survival., European Journal of Obstetrics & Gynecology and Reproductive Biology , 170, (1), 2013, p214 - 218 Journal Article, 2013 Other

Laios A, Mohamed BM, Kelly L, Flavin R, Finn S, McEvoy L, Gallagher M, Martin C, Sheils O, Ring M, Davies A, Lawson M, Gleeson N, D'Arcy T, d'Adhemar C, Norris L, Langhe R, Saadeh FA, O'Leary JJ, O'Toole SA, Pre-Treatment of Platinum Resistant Ovarian Cancer Cells with an MMP-9/MMP-2 Inhibitor Prior to Cisplatin Enhances Cytotoxicity as Determined by High Content Screening., International journal of molecular sciences, 14, (1), 2013, p2085-103 Journal Article, 2013 DOI TARA - Full Text

Abu Saadeh. F, Norris. L, O' Toole. S, Langhe. R, Gleeson. N., ETP as a marker for venous thromboembolism in gynaecologial cancer patients post surgery, International Journal of Gynecological Cancer, 14th Biennial Meeting of the International Gynecological Cancer Society., Vancouver, Canada, October 2012, 22, (Suppl 3), 2012, ppE249- Published Abstract, 2012

Abu Saadeh F, Norris L, O'Toole S, Langhe R, Gleeson N., Procoagulant activity in patients with gynecological malignancies and the effect of neoadjuvant chemotherapy , Thrombosis Research, 6th International Conference on Thrombosis & Hemostasis Issues in Cancer, Bergamo Italy, April 2012, edited by A Falanga, B. Brenner, F, Rickles , 129, (Suppl 1), Elsevier, 2012 Published Abstract, 2012 URL

Ismail SK, Norris L, Muttukrishna S, Higgins JR, Thrombin generation post elective caesarean section: Effect of low molecular weight heparin., Thrombosis research, 130, (5), 2012, p799 - 803 Journal Article, 2012 DOI

Abu Saadeh F, Norris L, O'Toole S, Langhe R, O'Leary JJ, Gleeson N., Does tissue factor and tissue factor pathway inhibitor over-expression play a role in the development of venous thromboembolism in ovarian cancer patients?, Thrombosis Research, 6th International Conference on Thrombosis & Hemostasis Issues in Cancer, Bergamo Italy, April 2012, edited by A Falanga, B. Brenner, F, Rickles , 129, ((Suppl 1)), Elsevier, 2012, pp170- Published Abstract, 2012 URL

Abu Saadeh. F, Norris. L, O' Toole. S, Langhe. R, O' Leary. J, Gleeson. N. , Why is venous thromboembolism is a common complication of ovarian cancer? , International Journal of Gynecological Cancer , 14th Biennial Meeting of the International Gynecological Cancer Society. , Vancouver, Canada, October 2012, 22, (Suppl 3), 2012, ppE247- Published Abstract, 2012

Abu Saadeh. F, Norris. L, O' Toole, Gleeson. N., Assessing the risk and mortality of venous thromboembolism in ovarian cancer., International Journal of Gynecological Cancer, 14th Biennial Meeting of the International Gynecological Cancer Society., Vancouver, Canada, October 2012, 22, (Suppl 3), 2012, ppE246- Meeting Abstract, 2012

Lynne Kelly, Shanthi Muttukrishna, Lucy Norris, John Higgins, P10. Placental expression of haemostatic and angiogenic markers in preeclampsia, Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 1, (3-4), 2011, p277 Journal Article, 2011

Egan K, Crowley D, Smyth P, O'Toole S, Spillane C, Martin C, Gallagher M, Canney A, Norris L, Conlon N, McEvoy L, Ffrench B, Stordal B, Keegan H, Finn S, McEneaney V, Laios A, Ducrée J, Dunne E, Smith L, Berndt M, Sheils O, Kenny D, O'Leary J, Platelet Adhesion and Degranulation Induce Pro-Survival and Pro-Angiogenic Signalling in Ovarian Cancer Cells, PLoS ONE, 6, (10, e26125), 2011 Journal Article, 2011 TARA - Full Text

Kelly LA, O'Leary JJ, Seidlova-Wuttke D, Wuttke W, Norris LA, Genistein alters coagulation gene expression in ovariectomised rats treated with phytoestrogens, Thrombosis and Haemostasis, 104, (6), 2010, p1083-1289 Journal Article, 2010 TARA - Full Text

Hellgren M, Conard J, Norris L, Kluft C, Cardiovascular risk markers during treatment with estradiol and trimegestone or dydrogesterone, Maturitas, 62, 2009, p287 - 293 Journal Article, 2009 DOI

Lucy A. Norris, Jeanette Brosnan, John Bonnar, Jacqueline Conard, Cornelius Kluft, Margareta Hellgren, Inhibitors and activation markers of the haemostatic system during hormone therapy: A comparative study of oral estradiol (2 mg)/ dydrogesterone and estradiol (2 mg)/ trimegestone, Thromb Haemost, 2008 Journal Article, 2008

Thrombosis Research, (2008), Marc Rodger, Henri Versteeg, [Editorial board member] Journal, 2008

Norris L A, Brosnan J, Bonnar J, Conard J, Kluft C, Hellgren M , INHIBITORS AND ACTIVATION MARKERS OF THE HAEMOSTATIC SYSTEM DURING HORMONE THERAPY: , Thrombosis and Haemostasis, 100, (2), 2008, p253 - 260 Journal Article, 2008

Brosnan JF, Sheppard BL, Norris LA, Haemostatic activation in post menopausal women taking low dose hormone therapy: less effect with transdermal administration?, Thrombosis and Haemostasis, 97, (4), 2007, p558 - 565 Journal Article, 2007 DOI

Norris LA, Weldon S, Nugent A & Roche HM , LPS induced tissue factor expression in the THP-1 monocyte cell line is attenuated by conjugated linoleic acid, Thrombosis Research, 117, 2006, p475 - 480 Journal Article, 2006

Yoneda M, Brosnan JF, Norris LA, Bonnar J, The effect of LMWH (Tinzaparin) on coagulation and fibrinolytic activation in pregnant women at risk of thrombosis, Thrombosis Research, 117, 2006, p283 - 290 Journal Article, 2006

Smith MP, Norris LA, Steer PJ, Savidge GF, Bonnar J, Tinzaparin sodium for thrombosis treatment and prevention during pregnancy., American Journal of Obstetrics and Gynaecology, 190, (4), 2004, p495 - 501 Journal Article, 2004

Norris LA, Bonnar J, Smith MP, Steer PJ, Savidge G, Low molecular weight heparin (tinzaparin) therapy for moderate risk thromboprophylaxis during pregnancy. A pharmacokinetic study, Thrombosis and Haemostasis, 92, (4), 2004, p791 - 796 Journal Article, 2004

Out, H.J., Jespersen, J., Pabinger, I., MacRae, K., Crosignani, P., Skouby, S.O., Winkler, U.H., Norris, L., Gaspard, U., David, Van Enk, A., Van De Ende, A., Mishell, D., Voncken, D., Klipping, C., Sidelmann, J., The effects of seven monophasic oral contraceptive regimens on hemostatic variables: Conclusions from a large randomized multicenter study, Contraception, 67, (3), 2003, p173-185 Journal Article, 2003

Oral Contraceptive and Hemostasis Study Group, The effects of seven monophasic oral contraceptive regimens on hemostatic variables: conclusions from a large multicentre study, Contraception, 67, (3), 2003, p173 - 185 Journal Article, 2003

Norris, Blood Coagulation (invited review), Best Practice Research in Clinical Obstetrics and Gynaecol, 17, (3), 2003, p369 - 383 Journal Article, 2003

Skouby, S.O., Jespersen, J., Kluft, C., Lowe, G.D.O., Norris, L., Stevenson, J., Samsioe, G., The European Consensus Development Conference 2002: Sex steroids and cardiovascular diseases: On the route to combined evidence from OC and HRT/ERT, Maturitas, 44, (1), 2003, p69-82 Journal Article, 2003

Norris LA, Joyce M, O'Keeffe N, Sheppard BL, Bonnar J., Haemostatic risk factors in healthy post menopausal women taking hormone replacement therapy, Maturitas, 43, (2), 2002, p125 - 133 Journal Article, 2002

Skouby SO, Jespersen J, Kluft C, Lowe GD, Norris L Samsoie G, Stevenson J. Writing group for the 3rd European Conference on Sex Steroids and Cardiovascular disease, On the route to combined evidence from OC and HRT/ERT, European Journal of Contraceptive Reproductive Health Care, 7, (4), 2002, p185 - 198 Journal Article, 2002

Skouby, S.O., Jespersen, J., Kluft, C., Lowe, G.D.O., Norris, L., Samsioe, G., Stevenson, J., On the route to combined evidence from OC and HRT/ERT, European Journal of Contraception and Reproductive Health Care, 7, (4), 2002, p185-198 Journal Article, 2002

John R Higgins, John Bonnar, Lucy A Norris, Michael R.N Darling, Joseph J Walshe, The Effect of Pre-eclampsia on Coagulation and Fibrinolytic Activation in the Neonate, Thrombosis Research, 99, (6), 2000, p567--570 Journal Article, 2000

Higgins JR, Bonnar J, Norris LA, Darling MR, Walshe JJ, The effect of pre-eclampsia on coagulation and fibrinolytic activation in the neonate, Thrombosis Research, 99, (6), 2000, p567 - 570 Journal Article, 2000

Wen Y, Doyle MC, Norris LA, Sinnot, MM, Cooke T, Harrison RF, Feely J, Combined oestrogen-progestogen replacement therapy does not inhibit low-density lipoprotein oxidation in post menopausal women, British Journal of Clinical Pharmacol, 47, (3), 1999, p315 - 321 Journal Article, 1999

Winkler, U.H., Norris, L., Gaspard, U., Van Enk, A., Mishell, D., Voncken, D., Klipping, C., An open label, randomized study to evaluate the effects of seven monophasic oral contraceptive regimens on hemostatic variables: Outline of the protocol, Contraception, 59, (6), 1999, p345-355 Journal Article, 1999

Bonnar J, Green R, Norris L, Perinatal aspects of inherited thrombophilia, Seminars in Thrombosis and Haemostasis, 25, (5), 1999, p481 - 485 Journal Article, 1999

Bonnar J, Norris LA, Green R, Low molecular weight heparin for thromboprophylaxis during caesarean section, Thrombosis Research, 96, (4), 1999, p317 - 322 Journal Article, 1999

The Oral Contraceptive and Hemostasis Study Group, An open label randomised study to evaluate the effects of seven monophasic oral contraceptive regimens on hemostatic variables, Contraception, 59, 1999, p345 - 355 Journal Article, 1999

Norris LA, Nitric Oxide in the Uteroplacental, fetoplacental and peripheral circulations in pre-eclampsia, Obstetrics and Gynaecology, 93, (6), 1999, p958 - 963 Journal Article, 1999

Wen Y, Killalea S, Norris LA, Cooke T, Feely J, Vitamin E suplementation in hyperlipidaemic patients: effect of increasing doses on in vitro and in vivo low-density lipoprotein oxidation, European Journal of Clinical Investigation, 29, (12), 1999, p1027 - 1034 Journal Article, 1999

Higgins JR, Walshe JJ, Darling MR, Norris L, Bonnar J, Hemostasis in the uteroplacental and peripheral circulations in normotensive and pre-eclamptic pregnancies, American Journal of Obstetrics and Gynaecology, 179, (2), 1998, p520 - 526 Journal Article, 1998

Comparative assessment of haemostatic variables with focus on levonorgestrel in, editor(s)Teichman AT, Corbin A , Levonorgestrel, Berlin, George Theime Verlag, 1998, pp39 - 46, [Bonnar J, Norris LA, Sheppard BL] Book Chapter, 1998

Adebayo GI, Norris L, Devitt M, Bonnar J, Feely J, Effects of oral contraceptive containing different progestogens on sodium lithium countertransport in normal females, Journal of Human Hypertension, 12, (4), 1998, p235 - 238 Journal Article, 1998

Bonnar J, Green R, Norris L, Inherited thrombophilia and pregnancy: the obstetric perspective, Seminars in Thrombosis and Haemostasis, 24, (Suppl (1)), 1998, p49 - 53 Journal Article, 1998

Norris LA, Bonnar J, Haemostatic changes and the oral contaceptive pill, Ballieres Clinics in Obstetrics and Gynaecology, 11, (3), 1997, p545 - 564 Journal Article, 1997

Lucy A. Norris, John Bonnar, 9 Haemostatic changes and the oral contraceptive pill, Baillière's Clinical Obstetrics and Gynaecology, 11, (3), 1997, p545--564 Journal Article, 1997

Norris LA, Bonnar J, The effect of oestrogen dose and progestogen type on haemostatic changes in women taking oral contraceptives, British Journal of Obstetrics and Gynaecology, 103, (3), 1996, p261 - 267 Journal Article, 1996

Wu J, Norris LA, Wen JC, Sheppard BL, Feely J, Bonnar J, The effect of hormone replacement therapy on plasma vitamin E levels in post menopausal women, European Journal of Obstetrics Gynaecology and reproductive biology, 66, (2), 1996, p151 - 154 Journal Article, 1996

Wu, J.J., Yakoob, J., Norris, L.A., Keeling, P.W.N., Is the fertile period reduced in patients with inflammatory bowel disease? Short report, Irish Journal of Medical Science, 165, (1), 1996, p35-36 Journal Article, 1996

Norris LA, Bonnar J, Increased whole blood aggregation in oral contraceptive users can be prevented in vitro by a thromboxane sythetase inhibitor, Gynecological Endocrinology, 10, (Supplement 2), 1996, p119 - 121 Journal Article, 1996

Wu JJ, Yakoob J, Norris LA, Keeling PW, Is the fertile period reduced in patients with inflammatory bowel disease, Irish Journal of Medical Science, 165, (1), 1996, p35 - 36 Journal Article, 1996

Norris LA, Devitt M, Bonnar J, The role of thromboxane A2 in increased whole blood platelet aggregation in oral contraceptive users, Thrombosis research, 81, (4), 1996, p407 - 417 Journal Article, 1996

Bloemenkamp K, Hannaford P, Helmerhorst F, Jespersen J, Kluft C, Norris L, Skouby S (Writing Group) , Consensus statement: Combined oral contraceptives and cardiovascular disease, Gynecological Endocrinology, 10 , (Supplement 2), 1996, p119 - 121 Journal Article, 1996

Norris LA, Bonnar J, Estrogen dose and progestogen type: their effect on hemostatic changes in oral contraceptive users, Gynecological Endocrinolgy, 10, (Supplement 2), 1996, p119 - 121 Journal Article, 1996

Norris LA, Bonnar J, New low dose oral contraceptives: less thrombotic risk, Modern medicine, 25, (9), 1995, p27 - 30 Journal Article, 1995

Norris LA, Bonnar J, New low dose oral contraceptives: less thrombotic risk?, Modern medicine, 25, (9), 1995, p27 - 30 Journal Article, 1995

Norris LA, Sex steroids and changes in the cardiovascular system I: Change in systems relevant to the development of cardiovascular disease- Annotation of Esbjerg I consensus meeting., Combined oral contraceptives and cardiovascular disease: Consensus Development meeting, Amsterdam , November , 1995, Published in Gynecological Endocrinology 1996;10: 25-27 Invited Talk, 1995

Norris LA, Bonnar J, The in vitro effect of aspirin on increased whole blood platelet aggregation in oral contraceptive users, Thrombosis Research, 74, (1), 1994, p309 - 315 Journal Article, 1994

Norris LA, Sheppard BL, Burke G, Bonnar J, Platelet activation in normotensive and hypertensive pregnancies complicated by intra-uterine growth retardation, British Journal of Obstetrics and Gynaecology, 101, (3), 1994, p209 - 214 Journal Article, 1994

Norris LA, Bonnar J, Effect of oestrogen dose on whole blood platelet activation in women taking new low dose oral contraceptives, Thrombosis and Haemostasis, 72, (6), 1994, p926 - 930 Journal Article, 1994

Norris LA, Gleeson N, Sheppard BL, Bonnar J, Whole blood platelet aggregation in moderate and severe pre-eclampsia, British Journal of Obstetrics and Gynaecology, 100, (7), 1993, p684 - 688 Journal Article, 1993

Norris LA, Platelet activation in pregnancy and oral contraception, Trinity College Dublin, 1992 Thesis, 1992

Norris LA, Sheppard BL, Bonnar J, Increased whole blood platelet aggregation in normal pregnancy can be prevented in vitro by aspirin and dazmegerel (UK38485), British Journal of Obstetrics and Gynaecology, 99, (3), 1992, p253 - 257 Journal Article, 1992

All 114 peer-reviewed publications

Research Expertise

Description

The role of coagulation proteases and platelets in the aetiology of gynaecological cancers. Development of risk models for the prediction of thrombosis in gynaecological cancer patients. The effect of chemotherapy in natural anticoagulant pathways. Aetiology of thrombosis risk in high risk pregnancy patients. Effects of oestrogens, progestogens and phytoestogens on coagulation gene expression and their role in thrombosis risk. The role of coagulation gene expression in the transition from endometriosis to clear cell cancer.

Recognition

Memberships

Member of International Society for Thrombosis and Haemostasis 2010 – 2020

Irish Society for Gynaecological Oncology 2016-present

Irish Association of Cancer Research 2015-present

Irish National Network for Ovarian Cancer Collaboration INNOVATION Founder member 2016 – Present