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Dr. Anne-Marie Baird
Research Fellow, Trinity Translational Medicine Institute

Publications and Further Research Outputs

Peer-Reviewed Publications

Sheill G., Brady L., Hayes B., Baird AM., Guinan E., Stanfill B., Vlayinic T., Casey O., Muphy V., Green J., Allott E., Hussey J., Cahill F., van Hemelrijck M., Peat N., Mucci L., Cunningham M., GroganL., Lynch T., Manecksha R.P., McCaffrey J., O"Donnell D., Sheils O., O"Leary J., Rudman S., McDermott R., Finn S., ExPeCT: A Randomised Trial Examining the Impact of Exercise on Quality of Life in Men with Metastatic Prostate Cancer, Supportive Care in Cancer, 31, (5), 2023, p292- Journal Article, 2023

Sanna Iivanainen, Anne-Marie Baird, Bogdana Balas, Alberto Bustillos, Amparo Yovanna Castro Sanchez, Manuela Eicher, Sophie Golding, Mathis Mueller-Ohldach, María Reig, Manfred Welslau, Johannes Ammann, Assessing the impact of digital patient monitoring on health outcomes and healthcare resource usage in addition to the feasibility of its combination with at-home treatment, in participants receiving systemic anticancer treatment in clinical practice: protocol for an interventional, open-label, multicountry platform study (ORIGAMA), BMJ Open, 13, (4), 2023, pe063242 Journal Article, 2023 DOI

Anne"Marie Baird, C. Benedikt Westphalen, Sandra Blum, Begonya Nafria, Tanya Knott, Ify Sargeant, Helena Harnik, Nicholas Brooke, Nicole Wicki, Durhane Wong"Rieger, How can we deliver on the promise of precision medicine in oncology and beyond? A practical roadmap for action, Health Science Reports, 6, (6), 2023 Journal Article, 2023 DOI

John Hallick, Anne-Marie Baird, Gerald Falchook, Xiuning Le, David Hong, Santiago Viteri, Jo Raskin, Niels Reinmuth, Soetkin Vlassak, Mihaela Militaru, Paul K Paik, Plain language summary of the development of tepotinib: a treatment for a subtype of non-small cell lung cancer called MET exon 14 skipping, Future Oncology, 19, (10), 2023, p683--696 Journal Article, 2023 DOI

Tendai Chihuri, Upal Basu Roy, Amy Moore, Anne-Marie Baird, Tracey L. Grant, Bellinda L. King-Kallimanis, Patient report on the impact of COVID-19 and living with lung cancer, JTO Clinical and Research Reports, 2023, p100549 Journal Article, 2023 DOI

Rachel J. Keogh, Martin P. Barr, Anna Keogh, David McMahon, Anne-Marie Baird, Seamus Cotter, David Breen, Gerard J. Fitzmaurice, David Fitzpatrick, Cathal O"Brien, Stephen P. Finn, Jarushka Naidoo, Lung Cancer in the Republic of Ireland, Journal of Thoracic Oncology, 18, (7), 2023, p851--857 Journal Article, 2023 DOI

Monica Racovita and Eleanor Wheeler and Tit Albreht and Silvia Novello and Anne-Marie Baird and Cornel Radu-Loghin and Jacek Jassem and Jan van Meerbeeck and Aoife McNamara, Lung cancer in Europe: The way forward, Tobacco Prevention & Cessation, 8, (February), 2022, p1--2 Journal Article, 2022 DOI

Anne-Marie Baird, Mark Lawler, Lynne Davies, Simon Oberst, Kathy Oliver, Alexander Eggermont, Anna Schmutz, Carlo La Vecchia, Claudia Allemani, Yolande Lievens, Peter Naredi, Tanja Cufer, Ajay Aggarwal, Matti Aapro, Kathi Apostolidis, Anne-Marie Baird, Fatima Cardoso, Andreas Charalambous, Michel P Coleman, Alberto Costa, Mirjam Crul, Csaba L Dégi, Federica Di Nicolantonio, Sema Erdem, Marius Geanta, Jan Geissler, Jacek Jassem, Beata Jagielska, Bengt Jonsson, Daniel Kelly, Olaf Kelm, Teodora Kolarova, Tezer Kutluk, Grant Lewison, Françoise Meunier, Jana Pelouchova, Thierry Philip, Richard Price, Beate Rau, Isabel T Rubio, Peter Selby, Maja Južni" Sotlar, Gilliosa Spurrier-Bernard, Jolanda C van Hoeve, Eduard Vrdoljak, Willien Westerhuis, Urszula Wojciechowska, Richard Sullivan, European Groundshot"addressing Europe's cancer research challenges: a Lancet Oncology Commission, The Lancet Oncology, 2022 Journal Article, 2022 DOI

Anne-Marie Baird, Martin Barr, Anne-Marie Baird, Sophia Halliday, Petra Martin, Emma H. Allott, James J. Phelan, Greg Korpanty, Linda Coate, Cathal O'Brien, Steven Gray, Jane S. Y. Sui, Brian Hayes, Sinead Cuffe, Stephen Finn, Liquid Biopsy: A Multi-Parametric Analysis of Mutation Status, Circulating Tumor Cells and Inflammatory Markers in EGFR-Mutated NSCLC, Diagnostics, 12, (10), 2022, p2360 Journal Article, 2022 DOI

Anne-Marie Baird, Anna Keogh, Lisa Ryan, Mutaz M. Nur, Anne-Marie Baird, Siobhan Nicholson, Sinéad Cuffe, Gerard J. Fitzmaurice, Ronan Ryan, Vincent K. Young, Stephen P. Finn, Steven G. Gray, USO1 expression is dysregulated in non-small cell lung cancer, Translational Lung Cancer Research, 11, (9), 2022, p1877--1895 Journal Article, 2022 DOI

Anne-Marie Baird, Ciara S. McNevin, Karen Cadoo, Anne-Marie Baird, Stephen Finn, Ray McDermott, PARP Inhibitors in Advanced Prostate Cancer in Tumors with DNA Damage Signatures, Cancers, 14, (19), 2022, p4751 Journal Article, 2022 DOI

Monica Racovita, Eleanor Wheeler, Suzanne Wait, Tit Albreht, Anne-Marie Baird, Jacek Jassem, Aoife McNamara, Silvia Novello, Cornel Radu-Loghin, Jan P. van Meerbeeck, The need for a comprehensive and integrated approach to lung cancer policy in Europe, European Journal of Cancer, 2022 Journal Article, 2022 DOI

Anne-Marie Baird, Re-engaging EU citizens with national screening programmes and cancer diagnosis post-pandemic, The Lancet Oncology, 23, (5), 2022, p566--567 Journal Article, 2022 DOI

McNevin CS, Cadoo K, Baird AM, Murchan P, Sheils O, McDermott R, Finn S., Pathogenic BRCA Variants as Biomarkers for Risk in Prostate Cancer., Cancers, 13, (22), 2021 Journal Article, 2021 DOI

Oner E, Kotmakci M, Baird AM, Gray SG, Debelec Butuner B, Bozkurt E, Kantarci AG, Finn SP., Development of EphA2 siRNA-loaded lipid nanoparticles and combination with a small-molecule histone demethylase inhibitor in prostate cancer cells and tumor spheroids., Journal of nanobiotechnology, 19, (71), 2021, p1-20 Journal Article, 2021 DOI URL TARA - Full Text

Shane Brennan and Anne-Marie Baird and Esther O'Regan and Orla Sheils, The Role of Human Papilloma Virus in Dictating Outcomes in Head and Neck Squamous Cell Carcinoma, Frontiers in Molecular Biosciences, 8, 2021 Journal Article, 2021 DOI

Raymond S. McDermott and John Greene and John McCaffrey and Imelda Parker and Sylva Helanova and Anne-Marie Baird and Ausra Teiserskiene and Marvin Lim and Helen Matthews and Olwyn Deignan and John Feeney and Pierre G. Thirion and Stephen P. Finn and Paul J. Kelly, Radium-223 in combination with enzalutamide in metastatic castration-resistant prostate cancer: a multi-centre, phase II open-label study, Therapeutic Advances in Medical Oncology, 13, 2021, p175883592110426 Journal Article, 2021 DOI

Lim MCJ, Baird AM, Greene J, McNevin C, Ronan K, Podlesniy P, Sheils O, Gray SG, McDermott RS, Finn SP., hsa_circ_0001275 Is One of a Number of circRNAs Dysregulated in Enzalutamide Resistant Prostate Cancer and Confers Enzalutamide Resistance In Vitro. , Cancers, 13, (24), 2021, p6383 Journal Article, 2021 DOI

Lauren Brady and Jessica Carlsson and Anne-Marie Baird and Orla Casey and Tatjana Vlajnic and Pierre Murchan and David Cormican and Danielle Costigan and Steven Gray and Orla Sheils and Amanda O{\textquotesingle, Correlation of integrated ERG/PTEN assessment with biochemical recurrence in prostate cancer, Cancer Treatment and Research Communications, 29, 2021, p100451 Journal Article, 2021 DOI

Pierre Murchan and Cathal {\'{O, Deep Learning of Histopathological Features for the Prediction of Tumour Molecular Genetics, Diagnostics, 11, (8), 2021, p1406 Journal Article, 2021 DOI

, Identification of Proteins Deregulated by Platinum-Based Chemotherapy as Novel Biomarkers and Therapeutic Targets in Non-Small Cell Lung Cancer, Frontiers in Oncology, 2021 Journal Article, 2021 DOI

Kate Dinneen, Anne-Marie Baird, Ciara Ryan, Orla Sheils, The Role of Cancer Stem Cells in Drug Resistance in Gastroesophageal Junction Adenocarcinoma, Frontiers in Molecular Biosciences, 2021 Journal Article, 2021

Baird AM, Finn SP, Gray SG, Sheils O., Epigenetic Modifier UHRF1 May Be a Potential Target in Malignant Pleural Mesothelioma., Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 16, (1), 2021, p14-16 Journal Article, 2021 DOI

Hayes B, Brady l, Sheill G, Baird AM, Guinan E, Stanfill B, Dunne J, Holden D, Vlajni T, Casey O, Murphy V, Greene J, Allott WH, Hussey J, Cahill F, Van Hemelrijck M, Peat N, Mucci L, Cunningham M, Grogan L, Lynch T, Manecksha RP, Mc Caffrey J, O'Donnell D, Sheils O, O'Leary J, Rudman S, Mc Dermott R, Finn S, Circulating tumour cell numbers correlate with platelet count and circulating lymphocyte subsets in men with advanced prostate cancer: Data from the ExPeCT clinical trial (CTRIAL-IE 15-21), Cancers, 13, (8), 2021, p4690- Journal Article, 2021

Upal Basu Roy and Anne-Marie Baird and Andrew Ciupek and Jesme Fox and Eugene Manley and Kim Norris and Giorgio V. Scagliotti and Heather A. Wakelee and Tetsuya Mitsudomi and Russell C. Clark and Renee Arndt and Fred R. Hirsch and Paul A. Bunn and Matthew P. Smeltzer, Impact of the COVID-19 Pandemic on Global Lung Cancer Clinical Trials: Why it matters to people with lung cancer, JTO Clinical and Research Reports, 2021, p100269 Journal Article, 2021 DOI

Daniel Di Capua and Dara Bracken-Clarke and Karine Ronan and Anne-Marie Baird and Stephen Finn, The Liquid Biopsy for Lung Cancer: State of the Art, Limitations and Future Developments, Cancers, 13, (16), 2021, p3923 Journal Article, 2021 DOI

Flynn L, Barr MP, Baird AM, Smyth P, Casey OM, Blackshields G, Greene J, Pennington SR, Hams E, Fallon PG, O'Leary J, Sheils O, Finn SP., Prostate cancer-derived holoclones: a novel and effective model for evaluating cancer stemness, SCIENTIFIC REPORTS, 10, 2020, p1132- Journal Article, 2020

Brady L, Hayes B, Sheill G, Baird AM, Guinan E, Stanfill B, Vlajnic T, Casey O, Murphy V, Greene J, Allott EH, Hussey J, Cahill F, Van Hemelrijck M, Peat N, Mucci L, Cunningham M, Grogan L, Lynch T, Manecksha RP, Mc Caffrey J, O'Donnell D, Sheils O, O'Leary J, Rudman S, Mc Dermott R, Finn S, Platelet cloaking of circulating tumour cells in patients with metastatic prostate cancer: Results from ExPeCT, a randomised controlled trial, Plos One, 15, (12), 2020 Journal Article, 2020

Baird AM, Easty D, Jarzabek M, Shiels L, Soltermann A, Klebe S, Raeppel S, MacDonagh L, Wu C, Griggs K, Kirschner MB, Stanfill B, Nonaka D, Goparaju CM, Murer B, Fennell DA, O'Donnell DM, Barr MP, Mutti L, Reid G, Finn S, Cuffe S, Pass HI, Opitz I, Byrne AT, O'Byrne KJ, Gray SG., When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?, Frontiers in endocrinology, 10, 2019, p89 Journal Article, 2019 DOI

John Aird, Anne-Marie Baird, Marvin C.J. Lim, Ray McDermott, Stephen P. Finn, Steven G. Gray, Carcinogenesis in prostate cancer: The role of long non-coding RNAs, Non-coding RNA Research, 3, (1), 2018, p29--38 Journal Article, 2018

Lim MCJ, Baird AM, Aird J, Greene J, Kapoor D, Gray SG, McDermott R, Finn SP., RNAs as Candidate Diagnostic and Prognostic Markers of Prostate Cancer-From Cell Line Models to Liquid Biopsies., Diagnostics (Basel), 8, (3), 2018 Journal Article, 2018 DOI

Greene John, Baird Anne-Marie, Brady Lauren, Lim Marvin, Gray Steven G, McDermott Raymond, Finn Stephen P, Circular RNAs: Biogenesis, Function and Role in Human Diseases , Frontiers in molecular biosciences , 4 , 2017, p38 - Journal Article, 2017 URL DOI

Burgess J.T, Bolderson E, Adams M.N, Baird A.-M, Zhang S.-D, Gately K.A, Umezawa K, O'Byrne K.J, Richard D.J, Activation and cleavage of SASH1 by caspase-3 mediates an apoptotic response, Cell Death and Disease, 7, (11), 2016, pe2469- Journal Article, 2016 URL DOI TARA - Full Text

O'Byrne, K., Barr, M.P., Urquhart, A., Ryan, S.-L., Gray, S.G., Davies, A., Richard, D., Gately, K., Baird, A.-M., 67P Investigation of the interaction between non-small cell lung cancer cells and immortalised normal bronchial epithelial cells, Journal of Thoracic Oncology, 11, (4), 2016, pS83-S84 Journal Article, 2016 DOI

O'Byrne, K., Ryan, S.-L., Baird, A.-M., Urquhart, A., Richard, D., Davies, A., 74P Elucidating drug resistance mechanisms using 2D and 3D culture systems, Journal of Thoracic Oncology, 11, (4), 2016, pS86-S87 Journal Article, 2016 DOI

Ryan S.-L, Baird A.-M, Vaz G, Urquhart A.J, Senge M, Richard D.J, O'Byrne K.J, Davies A.M, Drug Discovery Approaches Utilizing Three-Dimensional Cell Culture, Assay and Drug Development Technologies, 14, (1), 2016, p19 - 28 Journal Article, 2016 URL DOI

Baird AM, Gray SG, Richard DJ, O'Byrne KJ, Promotion of a cancer-like phenotype, through chronic exposure to inflammatory cytokines and hypoxia in a bronchial epithelial cell line model., Scientific reports, 6, 2016, p18907 Journal Article, 2016 DOI TARA - Full Text

O'Byrne, K., Ryan, S.-L., Heavey, S., Umezawa, K., Barr, M.P., Gray, S.G., Davies, A., Richard, D., Gately, K., Baird, A.-M., 68P Inflammatory meditated mechanisms of cisplatin resistance in non-small cell lung cancer, Journal of Thoracic Oncology, 11, (4), 2016, pS84 Journal Article, 2016 DOI

Perry AS, Baird AM, Gray SG, Epigenetic Methodologies for the Study of Celiac Disease., Methods in molecular biology (Clifton, N.J.), 1326, 2015, p131-58 Journal Article, 2015

Richard, D.J., Bolderson, E., Baird, A.-M., O'Byrne, K.J., Epigenetics Underpinning DNA Damage Repair, Epigenetic Cancer Therapy, 2015, p595-612 Journal Article, 2015

Baird, A.-M., Richard, D., O'Byrne, K.J., Gray, S.G., Epigenetic Therapy in Lung Cancer and Mesothelioma, Epigenetic Cancer Therapy, 2015, p189-213 Journal Article, 2015

Heavey S, Godwin P, Baird AM, Barr MP, Umezawa K, Cuffe S, Finn SP, O'Byrne KJ, Gately K, Strategic targeting of the PI3K-NF"B axis in cisplatin-resistant NSCLC., Cancer biology & therapy, 15, (10), 2014, p1367-77 Journal Article, 2014 DOI

Baird AM, Dockry E, Daly A, Stack E, Doherty DG, O'Byrne KJ, Gray SG, IL-23R is Epigenetically Regulated and Modulated by Chemotherapy in Non-Small Cell Lung Cancer., Frontiers in oncology, 3, 2013, p162- Journal Article, 2013 TARA - Full Text DOI

Baird AM, Leonard J, Naicker KM, Kilmartin L, O'Byrne KJ, Gray SG, IL-23 is pro-proliferative, epigenetically regulated and modulated by chemotherapy in non-small cell lung cancer., Lung cancer (Amsterdam, Netherlands), 79, (1), 2013, p83-90 Journal Article, 2013 DOI

Godwin P, Baird AM, Heavey S, Barr MP, O'Byrne KJ, Gately K., Targeting nuclear factor-kappa B to overcome resistance to chemotherapy., Frontiers in oncology, 3, 2013, p120 Journal Article, 2013 TARA - Full Text DOI

Baird, A.-M., Gray, S.G., O'Byrne, K., Inflammation in lung carcinogenesis, Lung Cancer: A Comprehensive Overview, 2013, p193-216 Journal Article, 2013

Baird AM, O'Byrne KJ, Gray SG, Epigenetic regulation of chemokine/chemokine receptor expression., Methods in molecular biology (Clifton, N.J.), 1013, 2013, p185-201 Journal Article, 2013 DOI

Gray SG, Baird AM, O'Kelly F, Nikolaidis G, Almgren M, Meunier A, Dockry E, Hollywood D, Ekström TJ, Perry AS, O'Byrne KJ, Gemcitabine reactivates epigenetically silenced genes and functions as a DNA methyltransferase inhibitor., International journal of molecular medicine, 30, (6), 2012, p1505-11 Journal Article, 2012 DOI

Baird, A.-M., O'Byrne, K.J., Gray, S.G., Reactive oxygen species and reactive nitrogen species in epigenetic modifications, Systems Biology of Free Radicals and Antioxidants, 2012, p437-455 Journal Article, 2012

Anne-Marie Baird, Steven G. Gray, Kenneth J. O'Byrne, Epigenetics Underpinning the Regulation of the CXC (ELR+) Chemokines in Non-Small Cell Lung Cancer, PLoS One, 6, (1), 2011, pe14593 Journal Article, 2011 DOI URL TARA - Full Text

Baird AM, Gray SG, O'Byrne KJ, IL-20 is epigenetically regulated in NSCLC and down regulates the expression of VEGF., European journal of cancer (Oxford, England : 1990), 47, (12), 2011, p1908-18 Journal Article, 2011 DOI

Baird AM, Gray SG, O'Byrne KJ, Epigenetics underpinning the regulation of the CXC (ELR+) chemokines in non-small cell lung cancer., PloS one, 6, (1), 2011, pe14593 Journal Article, 2011

Kenneth J. O'Byrne ; Anne-Marie Baird ; Lisa Kilmartin ; Jennifer Leonard ; Calen Sacevich ; Steven G. Gray, Epigenetic Regulation of Glucose Transporters in Non-Small Cell Lung Cancer, Cancers , 3, (2), 2011, p1550-1565 Journal Article, 2011 TARA - Full Text

Cathcart MC, Gray SG, Baird AM, Boyle E, Gately K, Kay E, Cummins R, Pidgeon GP, O'Byrne KJ, Prostacyclin synthase expression and epigenetic regulation in nonsmall cell lung cancer., Cancer, 117, (22), 2011, p5121-32 Journal Article, 2011 DOI

Gray SG, Al-Sarraf N, Baird AM, Cathcart MC, McGovern E, O'Byrne KJ, Regulation of EP receptors in non-small cell lung cancer by epigenetic modifications., European journal of cancer (Oxford, England : 1990), 45, (17), 2009, p3087-97 Journal Article, 2009 DOI

Gray, SG, Al-Sarraf, N, Baird, AM, Gately, K, McGovern, E, O'Byrne, KJ, Transcriptional regulation of IRS5/DOK4 expression in non-small-cell lung cancer cells., Clinical lung cancer, 9, (6), 2008, p367-374 Journal Article, 2008 DOI

Knorpp C, Johansson M, Baird AM, Plant mitochondrial nucleoside diphosphate kinase is attached to the membrane through interaction with the adenine nucleotide translocator., FEBS letters, 555, (2), 2003, p363-6 Journal Article, 2003

Research Expertise

Keywords

Anticancer therapies; Asbestos; Biochemical Markers; Biological Markers; Biomedical Research Training; Cancer/Carcinogenesis; Disease Model; Drug discovery; Drug Resistance; Gene Expression; Gene Regulation; Genomes, Genomics; Histology, Cytochemistry, Histochemistry; Immune System; In Vitro Testing, Trial Methods; Inhibitors; Lung Cancer; Medicine; Molecular Biology; Pathology; Screening of Drugs/Agents; Stem Cell; Tissue Culture