Publications and Further Research Outputs
Peer-Reviewed Publications
Rasha Shraim, Ross McManus, Lina Zgaga, Genome-wide GxE study with individualised ambient UV dose uncovers 162 novel vitamin D status variants, Vitamin D Workshop, Cork, 27-29 May 2024, 2024
Zhang X, He Y, Li X, Shraim R, Xu W, Wang L, Farrington SM, Campbell H, Timofeeva M, Zgaga L, Vaughan-Shaw P, Theodoratou E, Dunlop MG., Circulating 25-hydroxyvitamin D and survival outcomes of colorectal cancer: evidence from population-based prospective cohorts and Mendelian randomisation., British journal of cancer, 130, (9), 2024, p1585-1591
Lina Zgaga, Margaret M. Brennan, Jos van Geffen, Michiel van Weele, and Rasha Shraim, Ambient UVB, Supplements and Other Factors Interact to Impact Vitamin D Status Differently Depending on Ethnicity: Analysis of the UK Biobank, Vitamin D Workshop, Cork, 27-29 May 2024, 2024
Brennan MM, van Geffen J, van Weele M, Zgaga L, Shraim R., Ambient ultraviolet-B radiation, supplements and other factors interact to impact vitamin D status differently depending on ethnicity: A cross-sectional study., Clinical nutrition (Edinburgh, Scotland), 43, (6), 2024, p1308-1317
Leacy EJ, Teh JW, O'Rourke AM, Brady G, Gargan S, Conlon N, Scott J, Dunne J, Phelan T, Griffin MD, Power J, Mooney A, Naughton A, Kiersey R, Gardiner M, O'Brien C, Mullan R, Flood R, Clarkson M, Townsend L, O'Shaughnessy M, Dyer AH, Moran B, Fletcher JM, Zgaga L, Little MA, RITA Ireland Vasculitis Biobank., Effect of Immunosuppression on the Immune Response to SARS-CoV-2 Infection and Vaccination., International journal of molecular sciences, 25, (10), 2024, p5239
Shraim R, Farran MZ, He G, Marunica Karsaj J, Zgaga L, McManus R., Systematic review on gene-sun exposure interactions in skin cancer., Molecular genetics & genomic medicine, 11, (10), 2023, pe2259
Moran GP, Zgaga L, Daly B, Harding M, Montgomery T., Does fluoride exposure impact on the human microbiome?, Toxicology letters, 2023, pS0378-4274(23)00098-X
Shraim R, MacDonnchadha C, Vrbanic L, McManus R, Zgaga L., Share Gene-Environment Interactions in Vitamin D Status and Sun Exposure: A Systematic Review with Recommendations for Future Research., Nutrients, 14, (13), 2022, p2735-
Jennifer Scott, Enock Havyarimana, Albert Navarro-Gallinad, Arthur White, Jason Wyse, Jos van Geffen, Michiel van Weele, Antonia Buettner, Tamara Wanigasekera, Cathal Walsh, Louis Aslett, John D Kelleher, Julie Power, James Ng, Declan O'Sullivan, Lucy Hederman, Neil Basu, Mark A Little, Lina Zgaga, The association between ambient UVB dose and ANCA-associated vasculitis relapse and onset, Arthritis Research & Therapy, 24, (1), 2022, p1 - 14
Khanna T, Shraim R, Zarkovic M, van Weele M, van Geffen J, Zgaga L., Comprehensive Analysis of Seasonal and Geographical Variation in UVB Radiation Relevant for Vitamin D Production in Europe., Nutrients, 2022
Martin Dempster, Nicola O'Connell, Christopher D. Graham, Cliodhna O'Connor, Lina Zgaga, Emma Burke, Luke Mather, Gail Nicolson, Joe Barry, Gabriel Scally, Ann Nolan. Katy Tobin, Philip Crowley and Catherine D. Darker, Non-adherence to COVID-19 containment behaviours: results from an all-Ireland telephone surv, BMC Public Health, 22, (898), 2022
Zgaga L., Shraim R., Bolger E., Wyse J., Statistical power in vitamin D randomized control trials investigating biomarkers as continuous outcomes, The Journal of Steroid Biochemistry and Molecular Biology, 2022
Cliodhna O'Connor, Nicola O'Connell, Emma Burke, Martin Dempster, Christopher D. Graham, Gabriel Scally, Lina Zgaga, Ann Nolan, Gail Nicolson, Luke Mather, Joseph Barry, Philip Crowley, Catherine D. Darker,, Bordering on crisis: A qualitative analysis of focus group, social media, and news media perspectives on the Republic of Ireland-Northern Ireland border during the 'first wave' of the COVID-19 pandemic, Social Science and Medicine, 282, 2021
Li X, van Geffen J, van Weele M, Zhang X, He Y, Meng X, Timofeeva M, Campbell H, Dunlop M, Zgaga L, Theodoratou E., An observational and Mendelian randomisation study on vitamin D and COVID-19 risk in UK Biobank., 11, (1), 2021, p18262-
Wyse J, Mangan, R and Zgaga L, Power determination in vitamin D randomised control trials and characterising factors affecting it through a novel simulation-based tool, Scientific Reports, 11, 2021, p10804
O'Connor, C., O'Connell, N., Burke, E., Nolan, A., Dempster, M., Graham, C.D., Nicolson, G., Barry. J., Scally, G., Crowley, P., Zgaga, L., Mather,L., & Darker, C.D, Media Representations of Science during the First Wave of the COVID-19 Pandemic: A Qualitative Analysis of News and Social Media on the Island of Ireland, International Journal of Environmental Research and Public Health, 18, (9542), 2021
Vaughan-Shaw PG, Timofeeva M, Ooi LY, Svinti V, Grimes G, Smillie C, Blackmur JP, Donnelly K, Theodoratou E, Campbell H, Zgaga L, Din FVN, Farrington SM, Dunlop MG., Differential genetic influences over colorectal cancer risk and gene expression in large bowel mucosa., 149, (5), 2021, p1100-1108
Darker, C., O'Connell, N., Dempster, M., Graham, C., O'Connor, C., Zgaga, L., Nolan, A., Tobin, K., Brennan, N., Nicolson, G., Burke, E., Mather, L., Crowley, P., Scally, G., Barry, J., Study protocol for the COvid-19 Toolbox for All IslaNd (CONTAIN) project: A cross-border analysis in Ireland to disentangle psychological, behavioural, media and governmental responses to COVID-19, HRB Open Research, 2020, p10.12688/hrbopenres.13105.1
Madden JM, Leacy FP, Zgaga L, Bennett K., Fitting marginal structural and G-estimation models under complex treatment patterns: investigating the association between de novo vitamin D supplement use post breast cancer diagnosis and all-cause mortality using linked pharmacy claim and registry data., American Journal of Epidemiology, 189, (3), 2020, p224-234
Vaughan-Shaw PG, Buijs LF, Blackmur JP, Theodoratou E, Zgaga L, Din FVN, Farrington SM, Dunlop MG., The effect of vitamin D supplementation on survival in patients with colorectal cancer: systematic review and meta-analysis of randomised controlled trials., Br J Cancer. , 123, (11), 2020, p1705-1712
Lim ST, Thijs V, Murphy SJX, Fernandez-Cadenas I, Montaner J, Offiah C, Marquardt L, Kelly PJ, Bath PM, Lim SY, Ford GA, Norrving B, Cox D, Prodan CI, Barber PA, Werring DJ, Perry R, Zgaga L, Dawson J, McCabe DJH., Platelet function/reactivity testing and prediction of risk of recurrent vascular events and outcomes after TIA or ischaemic stroke: systematic review and meta-analysis., Journal of Neurology, 2020
Vaughan-Shaw PG, Zgaga L, Ooi LY, Theodoratou E, Timofeeva M, Svinti V, Walker M, O'Sullivan F, Ewing A, Johnston S, Din FVN, Campbell H, Farrington SM, Dunlop MG., Low plasma vitamin D is associated with adverse colorectal cancer survival after surgical resection, independent of systemic inflammatory response., Gut, 69, (1), 2019, p103-111
Vaughan-Shaw PG, Zgaga L, Theodoratou E, Blackmur JP, Dunlop MG., Whether vitamin D supplementation protects against colorectal cancer risk remains an open question., European Journal of Cancer, (115), 2019, p1-3
O'Sullivan F, Raftery T, van Weele M, van Geffen J, McNamara D, O'Morain C, Mahmud N, Kelly D, Healy M, O'Sullivan M, Zgaga L., Sunshine is an important determinant of vitamin D status even among high-dose supplement users: secondary analysis of a randomised controlled trial in Crohn's disease patients., Photochemistry and Photobiology, 95, (4), 2019, p1060 - 1067
L Zgaga, R Mangan, J Wyse, VITAMIN D RANDOMISED CONTROLLED TRIALS (RCTS) ARE OFTEN UNDERPOWERED: RESULTS FROM A SIMULATION-BASED APPROACH TO ESTIMATING POWER AND SAMPLE SIZE THAT ACCOUNTS FOR A LARGE INTER-INDIVIDUAL AND INTRA-INDIVIDUAL VARIABILITY., Vitamin D Workshop, New York, May 2019, 2019
Quigley C, Deady S, Hughes E, McElnea E, Zgaga L, Chetty S., National incidence of eyelid cancer in Ireland (2005-2015)., Eye, 33, (10), 2019, p1534-1539
Quigley C, Zgaga L, Vartsakis G, Fahy G., Refractive error and vision problems in children: association with increased sedentary behavior and reduced exercise in 9-year-old children in Ireland., Journal of AAPOS, 23, (3), 2019, p159.e1 - 159.e6
Law PJ, Timofeeva M, Fernandez-Rozadilla C, Broderick P, , Zgaga L, Brezina S, Gsur A, Cheadle JP, Aaltonen LA, Tomlinson I, Houlston RS, Dunlop MG., Association analyses identify 31 new risk loci for colorectal cancer susceptibility., Nature Communications, 10, (1), 2019, p2154-
Zgaga L, Laird E, Healy M, 25-Hydroxyvitamin D Measurement in Human Hair: Results from a Proof-of-Concept study, Nutrients, 11, (2), 2019, p423-
Meng X, Li X, Timofeeva MN, He Y, Spiliopoulou A, Wei WQ, Gifford A, Wu H, Varley T, Joshi P, Denny JC, Farrington SM, Zgaga L, Dunlop MG, McKeigue P, Campbell H, Theodoratou E., Phenome-wide Mendelian-randomization study of genetically determined vitamin D on multiple health outcomes using the UK Biobank study., International Journal of Epidemiology, 48, (5), 2019, p1425-1434
Markotic A, Langer S, Kelava T, Vucic K, Turcic P, Tokic T, Stefancic L, Radetic E, Farrington S, Timofeeva M, Rudan I, Campbell H, Dunlop M, Kirac I, Zgaga L., Higher Post-Operative Serum Vitamin D Level is Associated with Better Survival Outcome in Colorectal Cancer Patients., Nutrition and Cancer, 71, (7), 2019, p1078-1085.
L Zgaga, E Laird, M Healy, 25-HYDROXYVITAMIN D CAN BE MEASURED IN HUMAN HAIR., Vitamin D Workshop, New York, May 2019, 2019
Jo-Hanna Ivers, Lina Zgaga, Bernie O'Donoghue-Hynes, Aisling Heary, Brian Gallwey, Joe Barry, Five-year standardised mortality ratios in a cohort of homeless people in Dublin, BMJ Open, 9, (1), 2019
Madden JM, Murphy L, Zgaga L, Bennett K., De novo vitamin D supplement use post-diagnosis is associated with breast cancer survival., Breast cancer research and treatment, 172, (1), 2018, p179-190
Smith A, Murphy L, Zgaga L, Barron TI, Bennett K., Pre-diagnostic statin use, lymph node status and mortality in women with stages I-III breast cancer., Br J Cancer. , 117, (4), 2018, p588-596
Elío J., Crowley Q., Scanlon R., Hodgson J., Zgaga L., Estimation of residential radon exposure and definition of Radon Priority Areas based on expected lung cancer incidence, Environment International, 114, 2018, p69 - 76
O'Callaghan ME, Zgaga L, O'Ciardha D, O'Dowd T., Free Children's Visits and General Practice Attendance., Annals of family medicine, 16, (3), 2018, p246-249
Jiang X, O'Reilly PF, Aschard H, Aschard H, Hsu YH, Richards JB, Dupuis J, Ingelsson E, Karasik D, Pilz S, Berry D, Kestenbaum B, Zheng J, Luan J, Sofianopoulou E, Streeten EA, Albanes D, Lutsey PL, Yao L, Tang W, Econs MJ, Wallaschofski H, Völzke H, Zhou A, Power C, McCarthy MI, Michos ED, Boerwinkle E, Weinstein SJ, Freedman ND, Huang WY, Van Schoor NM, van der Velde N, Groot LCPGM, Enneman A, Cupples LA, Booth SL, Vasan RS, Liu CT, Zhou Y, Ripatti S, Ohlsson C, Vandenput L, Lorentzon M, Eriksson JG, Shea MK, Houston DK, Kritchevsky SB, Liu Y, Lohman KK, Ferrucci L, Peacock M, Gieger C, Beekman M, Slagboom E, Deelen J, Heemst DV, Kleber ME, März W, de Boer IH, Wood AC, Rotter JI, Rich SS, Robinson-Cohen C, den Heijer M, Jarvelin MR, Cavadino A, Joshi PK, Wilson JF, Hayward C, Lind L, Michaëlsson K, Trompet S, Zillikens MC, Uitterlinden AG, Rivadeneira F, Broer L, Zgaga L, Campbell H, Theodoratou E, Farrington SM, Timofeeva M, Dunlop MG, Valdes AM, Tikkanen E, Lehtimäki T, Lyytikäinen LP, Kähönen M, Raitakari OT, Mikkilä V, Ikram MA, Sattar N, Jukema JW, Wareham NJ, Langenberg C, Forouhi NG, Gundersen TE, Khaw KT, Butterworth AS, Danesh J, Spector T, Wang TJ, Hyppönen E, Kraft P, Kiel DP., Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels., Nature communications, 9, (1), 2018, p260
O'Sullivan F, van Geffen J, van Weele M, Zgaga L., Annual Ambient UVB at Wavelengths that Induce Vitamin D Synthesis is Associated with Reduced Esophageal and Gastric Cancer Risk: A Nested Case-Control Study., Photochemistry and photobiology, 94, (4), 2018, p797-806
Hayes, C.; Kelly, D.; Taut, C.; Nixon, E.; Zgaga, L.; Williams, J.; O'Dowd, T.; Reulbach, U. , Health Care Utilisation by Bullying Victims: A Cross-Sectional Study of a 9-Year-Old Cohort in Ireland, Healthcare, 6, (1), 2018, p19-
Crowley, Q., Elío, J., Scanlon, R., Hodgson, J., Long, S., Zgaga, L., Mapping and modelling radon for radiation protection and improved health, 71st Geological Congress of Turkey, METU, Ankara, 2018, pp927 - 927
Ivers JH, Zgaga L, Sweeney B, Keenan E, Darker C, Smyth BP, Barry J., A naturalistic longitudinal analysis of post-detoxification outcomes in opioid-dependent patients., Drug and Alcohol Review, 37, (S1), 2018, p339 - 347
Madden JM, Duffy MJ, Zgaga L, Bennett K., Trends in vitamin D supplement use in a general female and breast cancer population in Ireland: A repeated cross-sectional study., PloS one, 13, (12), 2018, pe0209033
He Y, Timofeeva M, Farrington SM, Vaughan-Shaw P, Svinti V, Walker M, Zgaga L, Meng X, Li X, Spiliopoulou A, Jiang X, Hyppönen E, Kraft P, Kiel DP, SUNLIGHT consortium, Hayward C, Campbell A, Porteous D, Vucic K, Kirac I, Filipovic M, Harris SE, Deary IJ, Houlston R, Tomlinson IP, Campbell H, Theodoratou E, Dunlop MG., Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk: a large Mendelian randomisation study., BMC medicine, 16, (1), 2018, p142
Moran S. M., Monach P. A., Zgaga L., Cuthbertson D., Carette S., Khalidi N. A., Koening C. L., Langford C. A., McAlear C. A., Moreland L., Pagnoux C., Seo P., Specks U., Sreih A., Wyse J., Ytterberg S. R., Merkel P. A. and Little M. A., Urinary soluble CD163 and monocyte chemoattractant protein-1 in the identification of subtle renal flare in anti-neutrophil cytoplasmic antibody-associated vasculitis, Nephrology Dialysis Transplantation, 2018, p1-9
Hinney A, Kesselmeier M, Jall S, Volckmar AL, Föcker M, Antel J; GCAN.; WTCCC3., Heid IM, et al., Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index., Mol Psychiatry, 22, (2), 2017, p192-201
Gilheaney O, Zgaga L, Harpur I, Sheaf G, Kiefer L, Bechet S, Walshe M, Prevalence of OD in Adults with TMD associated with RA: Examining the evidence, Dysphagia, ESSD Congress, Milan, Italy, 12-15 October 2016, 32, (1), 2017, pp178
Endocrine Oncology and Metabolism, Zagreb, Croatia, V.B.Z. d.o.o., Velikopoljska 12, [eds.], 2017
Gilheaney Ó., Zgaga L., Harpur I., Sheaf G., Kiefer L., Béchet S., Walshe M., The Prevalence of Oropharyngeal Dysphagia in Adults Presenting with Temporomandibular Disorders Associated with Rheumatoid Arthritis: A Systematic Review and Meta-analysis, Dysphagia, 32, (5), 2017, p587 - 600
Gilheaney O, Zgaga L, Harpur I, Kerr P, Walshe M, 'Prevalence of OD in Adults with TMD: A Systematic Review and Meta Analysis', PROSPERO International Register of Systematic Reviews, NHS National Institute for Health Research , 2017, - 1-5
Vaughan-Shaw PG, O'Sullivan F, Farrington SM, Theodoratou E, Campbell H, Dunlop MG, Zgaga L., The impact of vitamin D pathway genetic variation and circulating 25-hydroxyvitamin D on cancer outcome: systematic review and meta-analysis., Br J Cancer, 116, (8), 2017, p1092-1110
O'Sullivan F, Laird E, Kelly D, van Geffen J, van Weele M, McNulty H, Hoey L, Healy M, McCarroll K, Cunningham C, Casey M, Ward M, Strain JJ, Molloy AM, Zgaga L., Ambient UVB Dose and Sun Enjoyment Are Important Predictors of Vitamin D Status in an Older Population., Journal of Nutrition, 147, (5), 2017, p858-868.
Zgaga L, O'Sullivan F, Cantwell MM, Murray LJ, Thota PN, Coleman HG., Markers of Vitamin D Exposure and Esophageal Cancer Risk: A Systematic Review and Meta-analysis., Cancer Epidemiology Biomarkers and Prevention, 25, (6), 2016, p877-86
Weiss E, Zgaga L, Read S, Wild S, Dunlop MG, Campbell H, McQuillan R, Wilson JF., Farming, Foreign Holidays, and Vitamin D in Orkney., PLoS One, 11, (5), 2016, pe0155633
Gilheaney O, Harpur I, Sheaf G, Zgaga L, Walshe M, 'The Prevalence of oropharyngeal dysphagia in adults presenting with temporomandibular disorders and rheumatoid arthritis: Systematic review and meta analysis ', PROSPERO International Register of Systematic Reviews, NHS National Institute for Health Research , NHS National Institute for Health Research , 2016, - 1-6
Hayes C, Kearney M, O'Carroll H, Zgaga L, Geary M, Kelleher CC., Patterns of Smoking Behaviour in Low-Income Pregnant Women: A Cohort Study of Differential Effects on Infant Birth Weight., International Journal of Environmental Research and Public Health. , 13, (11), 2016, p1060-
Clare Quigley, Cristina Taut, Tamara Zigman, Louise Gallagher, Harry Campbell, Lina Zgaga, Association between Home Birth and Breast Feeding Outcomes: a Cross-Sectional Study in 28,125 Mother-Infant Pairs from Ireland and UK, British Medical Journal Open, 6, (e010551), 2016, p10.1136/bmjopen-2015- 010551
Taut C, Kelly A, Zgaga L, The Association Between Infant Temperament and Breastfeeding Duration: A Cross-Sectional Study., Breastfeeding Medicine, 2016, p11:111-8
Kelly D, Theodoratou E, Farrington S, Fraser R, Campbell H, Dunlop MG, Zgaga L., The Contributions of Adjusted Ambient UVB at the Place of Residence and Other Determinants to Serum 25-Hydroxyvitamin D Concentrations., British Journal of Dermatology, 174, (5), 2016, p1068-78
Amin N, Allebrandt KV, van der Spek A, Müller-Myhsok B, Hek K, Teder-Laving M, Hayward C, Esko T, van Mill JG, Mbarek H, Watson NF, Melville SA, Del Greco FM, Byrne EM, Oole E, Kolcic I, Chen TH, Evans DS, Coresh J, Vogelzangs N, Karjalainen J, Willemsen G, Gharib SA, Zgaga L, et al, Genetic variants in RBFOX3 are associated with sleep latency., Eur J Hum Genet, 24, (10), 2016, p1488-95
van den Berg SM, de Moor MH, Verweij KJ, Krueger RF, Luciano M, et al., Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium., Behav Genet. , epub ahead of print, 2015
Shungin D, Winkler TW, Croteau-Chonka DC, ...Morris AP, Lindgren CM, Mohlke KL (L Zgaga for The ReproGen Consortium), New genetic loci link adipose and insulin biology to body fat distribution., Nature, 518, (7538), 2015, p187-96
Journal of Global Health, Edinburgh, UK, Edinburgh University Global Health Society (EUGHS), [eds.], 2015
Locke AE, Kahali B, Berndt SI,... Hirschhorn JN, Loos RJ, Speliotes EK (L Zgaga for the The ReproGen Consortium), Genetic studies of body mass index yield new insights for obesity biology., Nature, 518, (7538), 2015, p197-206
Davies G, Armstrong N, Bis JC, Bressler J, Chouraki V, Giddaluru S, Hofer E, Ibrahim-Verbaas CA, Kirin M, Lahti J, van der Lee SJ, Le Hellard S, Liu T, Marioni RE, Oldmeadow C, Postmus I, Smith AV, Smith JA, Thalamuthu A, Thomson R, Vitart V, Wang J, Yu L, Zgaga L, et al. , Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949)., Molecular Psychiatry, 20, (2), 2015, p183-92
Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, Davies G, Trompet S, Smith JA, Wolf C, Chibnik LB, Liu Y, Vitart V, Kirin M, Petrovic K, Polasek O, Zgaga L, et al., GWAS for executive function and processing speed suggests involvement of the CADM2 gene, Molecular Psychiatry, epub ahead of print, 2015
Holleran G, Hall B, Zgaga L, Breslin N, McNamara D., The natural history of small bowel angiodysplasia., Scand J Gastroenterol, epub ahead of print, 2015
Debette S, Ibrahim Verbaas CA, Bressler J, Schuur M, Smith A, Bis JC, ... Zgaga L, ... et al., Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium., Biological Psychiatry, 77, (8), 2015, p749-63
Timofeeva MN, Kinnersley B, Farrington SM, Whiffin N, Palles C, Svinti V, Lloyd A, Gorman M, Ooi LY, Hosking F, Barclay E, Zgaga L, Dobbins S, Martin L, Theodoratou E, Broderick P, Tenesa A, Smillie C, Grimes G, Hayward C, Campbell A, Porteous D, Deary IJ, et al., Recurrent Coding Sequence Variation Explains Only A Small Fraction of the Genetic Architecture of Colorectal Cancer., Science Reports, 2015, p10;5:16286.
Genetics of Personality Consortium, de Moor MH, van den Berg SM, Verweij KJ,... Zgaga L, ...et al., Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder, JAMA Psychiatry, 72, (7), 2015, p642-50
Vimaleswaran KS, Cavadino A, Berry DJ; LifeLines Cohort Study investigators, Jorde R, Dieffenbach AK, Lu C, Alves AC, Heerspink HJ, Tikkanen E, Eriksson J, Wong A, Mangino M, Jablonski KA, Nolte IM, Houston DK, Ahluwalia TS, van der Most PJ, Pasko D, Zgaga L, et al., Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study., Lancet Diabetes Endocrinol, 2, (9), 2014, p719-29
Loth DW, Artigas MS, Gharib SA, Wain LV, Franceschini N, Koch B, Pottinger TD, Smith AV, Duan Q, Oldmeadow C, ... Zgaga L, et al., Genome-wide association analysis identifies six new loci associated with forced vital capacity., Nature Genetics, 47, (7), 2014, p669-77
Perry JR, Hsu YH, Chasman DI, Johnson AD, Elks C, Albrecht E, Andrulis IL, Beesley J, Berenson GS, Bergmann S, Bojesen SE, Bolla MK, Brown J, Buring JE, Campbell H, et al., DNA mismatch repair gene MSH6 implicated in determining age at natural menopause., Human Molecular Genetics, Epub ahead of print, 2014
Zgaga L, Theodoratou E, Farrington SM, Din FV, Ooi LY, Glodzik D, Johnston S, Tenesa A, Campbell H, Dunlop MG., Plasma Vitamin D Concentration Influences Survival Outcome After a Diagnosis of Colorectal Cancer, Journal of Clinical Oncology, 32, (23), 2014, p2430-9
Whiffin N, Hosking FJ, Farrington SM, Palles C, Dobbins SE, Zgaga L, Lloyd A, Kinnersley B, Gorman M, Tenesa A, Broderick P, Wang Y, Barclay E, Hayward C, Martin L, Buchanan DD, Ko Win A, Hopper J, Jenkins M, Lindor NM, Newcomb PA, Gallinger S, Conti D, Schumacher F, Casey G, Liu T; The Swedish Low-Risk Colorectal Cancer Study Group, Campbell H, Lindblom A, Houlston RS, Tomlinson IP, Dunlop MG., Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis., Human Molecular Genetics, 23, (17), 2014, p4729-37
Theodoratou E, Tzoulaki I, Zgaga L, Ioannidis JP., Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials., BMJ, 2014
van den Berg SM, de Moor MH, McGue M, Pettersson E, Terracciano A, Verweij KJ, Amin N, Derringer J, Esko T, ... Zgaga L, et al., Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory., Behav Genet. , 44, (4), 2014, p295-313
Vimaleswaran KS, Berry DJ, Lu C, Tikkanen E, Pilz S, Hiraki LT, Cooper JD, Dastani Z, Li R, Houston DK, Wood AR, Michaëlsson K, Vandenput L, Zgaga L, Yerges-Armstrong LM, McCarthy MI, Dupuis J, Kaakinen M, Kleber ME, Jameson K, Arden N, Raitakari O, et al., Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts., PLoS Medicine, 10, (2), 2013, pe1001383-
Cousminer DL, Berry DJ, Timpson NJ, Ang W, Thiering E, Byrne EM, Taal HR, Huikari V, Bradfield JP, Kerkhof M, Groen-Blokhuis MM, Kreiner-Møller E, Marinelli M, Holst C, et al., Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity., Human Molecular Genetics, 22, (13), 2013, p2735 - 2747
Zgaga L, Vitart V, Hayward C, Kastelan D, Polasek O, Jakovljevic M, Kolcic I, Biloglav Z, Wright AF, Campbell H, Walker BR, Rudan I., Individual multi-locus heterozygosity is associated with lower morning plasma cortisol concentrations., European Journal of Endocrinology, 169, (1), 2013, p59 - 64
Thorgeirsson TE, Gudbjartsson DF, Sulem P, Besenbacher S, Styrkarsdottir U, Thorleifsson G, Walters GB; TAG Consortium; Oxford-GSK Consortium; ENGAGE consortium, Furberg H, Sullivan PF, Marchini J, McCarthy MI, Steinthorsdottir V, Thorsteinsdottir U, Stefansson K., A common biological basis of obesity and nicotine addiction., Translational Psychiatry , 3, 2013, pe308 - e308
Evans DM, Brion MJ, Paternoster L, Kemp JP, McMahon G, Munafò M, Whitfield JB, Medland SE, Montgomery GW; GIANT Consortium; CRP Consortium; TAG Consortium, Timpson NJ, St Pourcain B, Lawlor DA, Martin NG, Dehghan A, Hirschhorn J, Davey Smith G., Mining the human phenome using allelic scores that index biological intermediates., PLoS Genetics, 9, (10), 2013, pe1003919 - e1003919
Lauc G, Huffman JE, Pučić M, Zgaga L, Adamczyk B, Mu inić A, Novokmet M, Pola ek O, Gornik O, Kri tić J, Keser T, Vitart V, Scheijen B, Uh HW, Molokhia M, Patrick AL, McKeigue P, et al., Loci associated with N-glycosylation of human immunoglobulin g show pleiotropy with autoimmune diseases and haematological cancers., PLoS Genetics, 9, (1), 2013, pe1003225
Zgaga L, Agakov F, Theodoratou E, Farrington SM, Tenesa A, Dunlop MG, McKeigue P, Campbell H., Model selection approach suggests causal association between 25-hydroxyvitamin D and colorectal cancer., PLoS One, 8, (5), 2013, pe63475 - e63475
Parsa A, Fuchsberger C, Köttgen A, O'Seaghdha CM, Pattaro C, de Andrade M, Chasman DI, et al., Common variants in mendelian kidney disease genes and their association with renal function., Journal of the American Society of Nephrology, 24, (12), 2013, p2105 - 2117
Kirac I, Mato ević P, Augustin G, imunović I, Hostić V, upančić S, Hayward C, Antoljak N, Rudan I, Campbell H, Dunlop MG, Velimir Vrdoljak D, Kovačević D, Zgaga L., SMAD7 variant rs4939827 is associated with colorectal cancer risk in Croatian population., PLoS One, 8, (9), 2013, pe74042 - e74042
Nair H, Lau E, Brooks W, Seong A, Theodoratou E, Zgaga L, Huda T, Jadhav SS, Rudan I, Campbell H, An evaluation of the emerging vaccines against influenza in children., BMC Public Health., 13 Suppl 3:S14, 2013
Rudan I, Theodoratou E, Zgaga L, Nair H, Chan KY, Tomlinson M, Tsai A, Biloglav Z, Huda T, El Arifeen S, Chopra M, Campbell H., Setting priorities for development of emerging interventions against childhood pneumonia, meningitis and influenza., Journal of Global Health, 2, (1), 2012, p10304
Asimit J, Day-Williams A, Zgaga L, Rudan I, Boraska V, Zeggini E., An evaluation of different meta-analysis approaches in the presence of allelic heterogeneity., European Journal of Human Genetics, 20, (6), 2012, p709-12
McQuillan R, Eklund N, Pirastu N, Kuningas M, McEvoy BP, Esko T, Corre T, Davies G, et al., Evidence of inbreeding depression on human height., PLoS Genetics, 8, (7), 2012, pe1002655
Kirac I, Sekerija M, Simunović I, Zgaga L, Velimir Vrdoljak D, Kovacević D, Kulis T, Znaor A., Incidence and mortality trends of gastric and colorectal cancers in Croatia, 1988-2008., Croatian Medical Journal, 53, (2), 2012, p124-34
Boraska V, Day-Williams A, Franklin CS, Elliott KS, Panoutsopoulou K, Tachmazidou I, Albrecht E, Bandinelli S, Beilin LJ, et al., Genome-wide association study to identify common variants associated with brachial circumference: a meta-analysis of 14 cohorts., PLoS One, 7, (3), 2012, pe31369
Thanabalasingham G, Huffman JE, Kattla JJ, Novokmet M, Rudan I, Gloyn AL, Hayward C, Adamczyk B, Reynolds RM, Muzinic A, Hassanali N, Pucic M, Bennett AJ, Essafi A, Polasek O, Mughal SA, Redzic I, Primorac D, Zgaga L, Kolcic I, Hansen T, Gasperikova D, Tjora E, Strachan MW, Nielsen T, Stanik J, Klimes I, Pedersen OB, Njølstad PR, Wild SH, Gyllensten U, Gornik O, Wilson JF, Hastie ND, Campbell H, McCarthy MI, Rudd PM, Owen KR, Lauc G, Wright AF., Mutations in HNF1A Result in Marked Alterations of Plasma Glycan Profile., Diabetes, 2012
Boraska V, Jerončić A, Colonna V, Southam L, Nyholt DR, Rayner NW, Perry JR, Toniolo D, Albrecht E, Ang W, Bandinelli S, et al., Genome-wide meta-analysis of common variant differences between men and women., Human Molecular Genetics, 21, (21), 2012, p4805-15
Dowman B, Campbell RM, Zgaga L, Adeloye D, Chan KY., Estimating the burden of rheumatoid arthritis in Africa: A systematic analysis., Journal of Global Health, 2, (2), 2012, p20406
Stolk L, Perry JR, Chasman DI, He C, Mangino M, Sulem P, Barbalic M, Broer L, et al., Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways., Nature Genetics, 44, (3), 2012, p260-8
Franceschini N, van Rooij FJ, Prins BP, Feitosa MF, Karakas M, Eckfeldt JH, Folsom AR, Kopp J, Vaez A, Andrews JS, Baumert J, Boraska V, Broer L, Hayward C, Ngwa JS, Okada Y, Polasek O, Westra HJ, Wang YA, Del Greco M F, Glazer NL, Kapur K, Kema IP, Lopez LM, Schillert A, Smith AV, Winkler CA, Zgaga L; LifeLines Cohort Study, Bandinelli S, et al., Discovery and fine mapping of serum protein loci through transethnic meta-analysis., American Journal of Human Genetics, 91, (4), 2012, p744-53
Dunlop MG, Dobbins SE, Farrington SM, Jones AM, Palles C, Whiffin N, Tenesa A, Spain S, Broderick P, Ooi LY, Domingo E, Smillie C, Henrion M, Frampton M, Martin L, Grimes G, Gorman M, Semple C, Ma YP, Barclay E, Prendergast J, Cazier JB, Olver B, Penegar S, Lubbe S, Chander I, Carvajal-Carmona LG, Ballereau S, Lloyd A, Vijayakrishnan J, Zgaga L, Rudan I, Theodoratou E; Colorectal Tumour Gene Identification (CORGI) Consortium, Starr JM, et al., Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk., Nature Genetics, 44, (7), 2012, p770-6
Zgaga L, Theodoratou E, Kyle J, Farrington SM, Agakov F, Tenesa A, Walker M, McNeill G, Wright AF, Rudan I, Dunlop MG, Campbell H., The association of dietary intake of purine-rich vegetables, sugar-sweetened beverages and dairy with plasma urate, in a cross-sectional study., PLoS One, 7, (6), 2012, pe38123-
Yang J, Loos RJ, Powell JE, Medland SE, Speliotes EK, Chasman DI, Rose LM, Thorleifsson G, Steinthorsdottir V, Mägi R, Waite L, et al., FTO genotype is associated with phenotypic variability of body mass index., Nature, 490, (7419), 2012, p267-72
Zaboli G, Ameur A, Igl W, Johansson Å, Hayward C, Vitart V, Campbell S, Zgaga L, Polasek O, Schmitz G, van Duijn C, Oostra B, Pramstaller P, Hicks A, Meitinger T, Rudan I, Wright A, Wilson JF, Campbell H, Gyllensten U; EUROSPAN Consortium., Sequencing of high-complexity DNA pools for identification of nucleotide and structural variants in regions associated with complex traits., European Journal of Human Genetics, 20, (1), 2012, p77-83
Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, et al, A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance., Nature Genetics, 44, (6), 2012, p659-69
Theodoratou E, Montazeri Z, Hawken S, Allum GC, Gong J, Tait V, Kirac I, Tazari M, Farrington SM, Demarsh A, Zgaga L, Landry D, Benson HE, Read SH, Rudan I, Tenesa A, Dunlop MG, Campbell H, Little J., Systematic meta-analyses and field synopsis of genetic association studies in colorectal cancer., Journal of the National Cancer Instute, 104, (19), 2012, p1433-57
Luciano M, Huffman JE, Arias-Vásquez A, Vinkhuyzen AA, Middeldorp CM, Giegling I, Payton A, Davies G, Zgaga L, Janzing J, Ke X, Galesloot T, Hartmann AM, Ollier W, et al., Genome-wide association uncovers shared genetic effects among personality traits and mood states., American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 159B, (6), 2012, p684-95
Chasman DI, Fuchsberger C, Pattaro C, Teumer A, Böger CA, Endlich K, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O'Seaghdha CM, et al., Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function., Human Molecular Genetics, 21, (24), 2012, p5329-43
Okada Y, Sim X, Go MJ, Wu JY, Gu D, Takeuchi F, Takahashi A, Maeda S, Tsunoda T, Chen P, et al., Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations., Nature Genetics, 44, (8), 2012, p904-9
Murabito JM, White CC, Kavousi M, Sun YV, Feitosa MF, Nambi V, et al., Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies., Circulation: Cardiovascular Genetics, 5, (1), 2012, p100-12
Theodoratou E, Palmer T, Zgaga L, Farrington SM, McKeigue P, Din FV, Tenesa A, Davey-Smith G, Dunlop MG, Campbell H., Instrumental variable estimation of the causal effect of plasma 25-hydroxy-vitamin D on colorectal cancer risk: a mendelian randomization analysis., PLoS One, 7, (6), 2012, pe37662
Obeidat M, Wain LV, Shrine N, Kalsheker N, Soler Artigas M, Repapi E, Burton PR, Johnson T, Ramasamy A, Zhao JH, Zhai G, Huffman JE, Vitart V, Albrecht E, Igl W, Hartikainen AL, Pouta A, Cadby G, Hui J, Palmer LJ, Hadley D, McArdle WL, Rudnicka AR, Barroso I, Loos RJ, Wareham NJ, Mangino M, Soranzo N, Spector TD, Gläser S, Homuth G, Völzke H, Deloukas P, Granell R, Henderson J, Grkovic I, Jankovic S, Zgaga L, Pola ek O, Rudan I, Wright AF, Campbell H, Wild SH, Wilson JF, Heinrich J, Imboden M, Probst-Hensch NM, Gyllensten U, Johansson Å, Zaboli G, Mustelin L, Rantanen T, Surakka I, Kaprio J, Jarvelin MR, Hayward C, Evans DM, Koch B, Musk AW, Elliott P, Strachan DP, Tobin MD, Sayers I, Hall IP; SpiroMeta Consortium., A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample., PLoS One, 6, (5), 2011, pe19382
Böger CA, Chen MH, Tin A, Olden M, Köttgen A, de Boer IH, Fuchsberger C, O'Seaghdha CM, et al., CUBN is a gene locus for albuminuria., Journal of the American Society of Nephrology, 22, (3), 2011, p555-70
Speliotes EK, Yerges-Armstrong LM, Wu J, Hernaez R, Kim LJ, Palmer CD, Gudnason V, Eiriksdottir G, Garcia ME, Launer LJ, Nalls MA, Clark JM, Mitchell BD, Shuldiner AR, Butler JL, Tomas M, Hoffmann U, Hwang SJ, Massaro JM, O'Donnell CJ, Sahani DV, Salomaa V, Schadt EE, Schwartz SM, Siscovick DS; NASH CRN; GIANT Consortium; MAGIC Investigators, Voight BF, Carr JJ, Feitosa MF, Harris TB, Fox CS, Smith AV, Kao WH, Hirschhorn JN, Borecki IB; GOLD Consortium., Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits., PLoS Genetics, 7, (3), 2011, pe1001324
Higginson D, Theodoratou E, Nair H, Huda T, Zgaga L, Jadhav SS, Omer SB, Rudan I, Campbell H., An evaluation of respiratory administration of measles vaccine for prevention of acute lower respiratory infections in children., BMC Public Health, 11, (Suppl 3), 2011, pS31
Nair H, Verma VR, Theodoratou E, Zgaga L, Huda T, Simões EA, Wright PF, Rudan I, Campbell H., An evaluation of the emerging interventions against Respiratory Syncytial Virus (RSV)-associated acute lower respiratory infections in children., BMC Public Health, 11, (Suppl 3), 2011, pS30
Webster J, Theodoratou E, Nair H, Seong AC, Zgaga L, Huda T, Johnson HL, Madhi S, Rubens C, Zhang JS, El Arifeen S, Krause R, Jacobs TA, Brooks AW, Campbell H, Rudan I., An evaluation of emerging vaccines for childhood pneumococcal pneumonia., BMC Public Health, 11, (Suppl 3), 2011, pS26
Sivakumaran S, Agakov F, Theodoratou E, Prendergast JG, Zgaga L, Manolio T, Rudan I, McKeigue P, Wilson JF, Campbell H., Abundant pleiotropy in human complex diseases and traits., American Journal of Human Genetics, 89, (5), 2011, p607-18
Huffman JE, Knezevic A, Vitart V, Kattla J, Adamczyk B, Novokmet M, Igl W, Pucic M, Zgaga L, Johannson Å, Redzic I, Gornik O, Zemunik T, Polasek O, Kolcic I, Pehlic M, Koeleman CA, Campbell S, Wild SH, Hastie ND, Campbell H, Gyllensten U, Wuhrer M, Wilson JF, Hayward C, Rudan I, Rudd PM, Wright AF, Lauc G., Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults., Human Molecular Genetics, 20, (24), 2011, p5000-11
Chambers JC, Zhang W, Sehmi J, Li X, Wass MN, Van der Harst P, Holm H, Sanna S, Kavousi M, Baumeister SE, Coin LJ, et al., Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma., Nature Genetics, 43, (11), 2011, p1131-8
Rudan I, Chopra M, Aulchenko Y, Baqui AH, Bhutta ZA, Edmond K, Horta BL, Klugman KP, Lanata CF, Madhi SA, Nair H, Qureshi Z, Rubens C, Theodoratou E, Victora CG, Wang W, Weber MW, Wilson JF, Zgaga L, Campbell H., The case for launch of an international DNA-based birth cohort study., Journal of Global Health, 1, (1), 2011, p39-45
Huda T, Nair H, Theodoratou E, Zgaga L, Fattom A, El Arifeen S, Rubens C, Campbell H, Rudan I., An evaluation of the emerging vaccines and immunotherapy against staphylococcal pneumonia in children., BMC Public Health, 11, (Suppl 3), 2011, pS27
Wain LV, Verwoert GC, O'Reilly PF, Shi G, Johnson T, Johnson AD, Bochud M, et al., Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure., Nature Genetics, 43, (10), 2011, p1005-11
Zgaga L, Theodoratou E, Farrington SM, Agakov F, Tenesa A, Walker M, Knox S, Wallace AM, Cetnarskyj R, McNeill G, Kyle J, Porteous ME, Dunlop MG, Campbell H., Diet, environmental factors, and lifestyle underlie the high prevalence of vitamin D deficiency in healthy adults in Scotland, and supplementation reduces the proportion that are severely deficient., Journal of Nutrition, 141, (8), 2011, p1535-42
Catto AG, Zgaga L, Theodoratou E, Huda T, Nair H, El Arifeen S, Rudan I, Duke T, Campbell H., An evaluation of oxygen systems for treatment of childhood pneumonia., BMC Public Health, 11, (Suppl 3), 2011, pS28
Choudhuri D, Huda T, Theodoratou E, Nair H, Zgaga L, Falconer R, Luksic I, Johnson HL, Zhang JS, El Arifeen S, Nelson CB, Borrow R, Campbell H, Rudan I., An evaluation of emerging vaccines for childhood meningococcal disease., BMC Public Health, 11, (Suppl 3), 2011, pS29
Strawbridge RJ, Dupuis J, Prokopenko I, Barker A, Ahlqvist E, Rybin D, Petrie JR, Travers ME, Bouatia-Naji N, Dimas AS, Nica A, Wheeler E, Chen H, Voight BF, et al., Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes., Diabetes, 60, (10), 2011, p2624-34
Pola ek O, Leutenegger AL, Gornik O, Zgaga L, Kolcic I, McQuillan R, Wilson JF, Hayward C, Wright AF, Lauc G, Campbell H, Rudan I., Does inbreeding affect N-glycosylation of human plasma proteins?, Molecular Genetics and Genomics, 285, (5), 2011, p427-32
Soler Artigas M, Loth DW, Wain LV, Gharib SA, Obeidat M, Tang W, et al., Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function., Nature Genetics, 43, (11), 2011, p1082-90
International Consortium for Blood Pressure Genome-Wide Association Studies, Ehret GB, Munroe PB, Rice KM, et al., Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk., Nature, 478, (7367), 2011, p103-9
Waters D, Jawad I, Ahmad A, Luk ić I, Nair H, Zgaga L, Theodoratou E, Rudan I, Zaidi AK, Campbell H., Aetiology of community-acquired neonatal sepsis in low and middle income countries., Journal of Global Health, 1, (2), 2011, p154-70
Jeroncić I, Mulić R, Klismanić Z, Rudan D, Boban M, Zgaga L., Interactions between genetic variants in glucose transporter type 9 (SLC2A9) and dietary habits in serum uric acid regulation., Croatian Medical Journal, 51, (1), 2010, p40-7
Lauc G, Essafi A, Huffman JE, Hayward C, Kne ević A, Kattla JJ, Pola ek O, Gornik O, Vitart V, Abrahams JL, Pučić M, Novokmet M, Red ić I, Campbell S, Wild SH, Borovečki F, Wang W, Kolčić I, Zgaga L, Gyllensten U, Wilson JF, Wright AF, Hastie ND, Campbell H, Rudd PM, Rudan I., Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation., PLoS Genetics, 6, (12), 2010, pe1001256
Elks CE, Perry JR, Sulem P, Chasman DI, Franceschini N, He C, Lunetta KL, Visser JA, Byrne EM, Cousminer DL, Gudbjartsson DF, Esko T, Feenstra B, Hottenga JJ, Koller DL, Kutalik Z, Lin P, Mangino M, Marongiu M, McArdle PF, Smith AV, Stolk L, van Wingerden SH, Zhao JH, Albrecht E, Corre T, Ingelsson E, Hayward C, Magnusson PK, Smith EN, Ulivi S, Warrington NM, Zgaga L, Alavere H, Amin N, Aspelund T, Bandinelli S, et al., Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies., Nature Genetics, 42, (12), 2010, p1077-85
Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, et al., Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index., Nature Genetics, 42, (11), 2010, p937-48
Pattaro C, De Grandi A, Vitart V, Hayward C, Franke A, Aulchenko YS, Johansson A, Wild SH, Melville SA, Isaacs A, Polasek O, Ellinghaus D, Kolcic I, Nöthlings U, Zgaga L, Zemunik T, Gnewuch C, Schreiber S, Campbell S, Hastie N, Boban M, Meitinger T, Oostra BA, Riegler P, Minelli C, Wright AF, Campbell H, van Duijn CM, Gyllensten U, Wilson JF, Krawczak M, Rudan I, Pramstaller PP; EUROSPAN consortium., A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level., BMC Medical Genetics, 11, (41), 2010
Liu JZ, Tozzi F, Waterworth DM, Pillai SG, Muglia P, Middleton L, Berrettini W, Knouff CW, Yuan X, Waeber G, Vollenweider P, Preisig M, Wareham NJ, Zhao JH, Loos RJ, Barroso I, Khaw KT, Grundy S, Barter P, Mahley R, Kesaniemi A, McPherson R, Vincent JB, Strauss J, Kennedy JL, Farmer A, McGuffin P, Day R, Matthews K, Bakke P, Gulsvik A, Lucae S, Ising M, Brueckl T, Horstmann S, Wichmann HE, Rawal R, Dahmen N, Lamina C, Polasek O, Zgaga L, Huffman J, Campbell S, Kooner J, Chambers JC, Burnett MS, Devaney JM, Pichard AD, Kent KM, Satler L, Lindsay JM, Waksman R, Epstein S, Wilson JF, Wild SH, Campbell H, Vitart V, Reilly MP, Li M, Qu L, Wilensky R, Matthai W, Hakonarson HH, Rader DJ, Franke A, Wittig M, Schäfer A, Uda M, Terracciano A, Xiao X, Busonero F, Scheet P, Schlessinger D, St Clair D, Rujescu D, Abecasis GR, Grabe HJ, Teumer A, Völzke H, Petersmann A, John U, Rudan I, Hayward C, Wright AF, Kolcic I, Wright BJ, Thompson JR, Balmforth AJ, Hall AS, Samani NJ, Anderson CA, Ahmad T, Mathew CG, Parkes M, Satsangi J, Caulfield M, Munroe PB, Farrall M, Dominiczak A, Worthington J, Thomson W, Eyre S, Barton A; Wellcome Trust Case Control Consortium, Mooser V, Francks C, Marchini J., Meta-analysis and imputation refines the association of 15q25 with smoking quantity., Nature Genetics, 42, (5), 2010, p436-40
Franklin CS, Aulchenko YS, Huffman JE, Vitart V, Hayward C, Pola ek O, Knott S, Zgaga L, Zemunik T, Rudan I, Campbell H, Wright AF, Wild SH, Wilson JF., The TCF7L2 diabetes risk variant is associated with HbA₁(C) levels: a genome-wide association meta-analysis., Annals of Human Genetics, 74, (6), 2010, p471-8
Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, et al., Hundreds of variants clustered in genomic loci and biological pathways affect human height., Nature, 467, (7317), 2010, p832-8
Vitart V, Bencić G, Hayward C, Skunca Herman J, Huffman J, Campbell S, Bućan K, Navarro P, Gunjaca G, Marin J, Zgaga L, Kolcić I, Polasek O, Kirin M, Hastie ND, Wilson JF, Rudan I, Campbell H, Vatavuk Z, Fleck B, Wright A., New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8., Human Molecular Genetics, 19, (21), 2010, p4304-11
Vitart V, Bencić G, Hayward C, Herman JS, Huffman J, Campbell S, Bućan K, Zgaga L, Kolcić I, Polasek O, Campbell H, Wright A, Vatavuk Z, Rudan I., Heritabilities of ocular biometrical traits in two croatian isolates with extended pedigrees., Investigative Ophthalmology & Visual Science, 51, (2), 2010, p737-43
Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, et al., Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution., Nature Genetics, 42, (11), 2010, p949-60
Köttgen A, Pattaro C, Böger CA, Fuchsberger C, Olden M, Glazer NL, Parsa A, Gao X, Yang Q, Smith AV, O'Connell JR, Li M, et al., New loci associated with kidney function and chronic kidney disease., Nature Genetics, 42, (5), 2010, p376-84.
Repapi E, Sayers I, Wain LV, Burton PR, Johnson T, Obeidat M, Zhao JH, Ramasamy A, Zhai G, Vitart V, Huffman JE, Igl W, Albrecht E, Deloukas P, Henderson J, Granell R, McArdle WL, Rudnicka AR; Wellcome Trust Case Control Consortium, Barroso I, Loos RJ, Wareham NJ, Mustelin L, Rantanen T, Surakka I, Imboden M, Wichmann HE, Grkovic I, Jankovic S, Zgaga L, Hartikainen AL, Peltonen L, et al., Genome-wide association study identifies five loci associated with lung function., Nature Genetics, 42, (1), 2010, p36-44
Polasek O, Gunjaca G, Kolcić I, Zgaga L, Dzijan S, Smolić R, Smolić M, Milas-Ahić J, Serić V, Galić J, Tucak-Zorić S, Tucak A, Rudan I, Lauc G., Association of nephrolithiasis and gene for glucose transporter type 9 (SLC2A9): study of 145 patients., Croatian Medical Journal, 51, (1), 2010, p48-53
Navarro P, Vitart V, Hayward C, Tenesa A, Zgaga L, Juricic D, Polasek O, Hastie ND, Rudan I, Campbell H, Wright AF, Haley CS, Knott SA., Genetic comparison of a Croatian isolate and CEPH European founders., Genetic Epidemiology, 34, (2), 2010, p140-5
Kolcić I, Biloglav Z, Zgaga L, Jović AV, Curić I, Curić S, Susac J, Velagić V, Matec L, Zobić I, Zedelj J, Strnad M., Prevalence of increased body weight and hypertension in the population of Croatian mainland and Adriatic Islands--are islanders really healthier?, Collegium Antropologicum, 33, (Suppl 1), 2009, p135-40
Biloglav Z, Zgaga L, Smoljanović M, Hayward C, Polasek O, Kolcić I, Vitart V, Zemunik T, Boraska V, Torlak V, Mulić R, Ropac D, Grković I, Rudan D, Ristić S, Barbalić M, Campbell H, Wright AF, Rudan I., Historic, demographic, and genetic evidence for increased population frequencies of CCR5Delta32 mutation in Croatian Island isolates after lethal 15th century epidemics., Croatian Medical Journal, 50, (1), 2009, p34-42
Vatavuk Z, Skunca Herman J, Bencić G, Andrijević Derk B, Lacmanović Loncar V, Petric Vicković I, Bucan K, Mandić K, Mandić A, Skegro I, Pavicić Astalos J, Merc I, Martinović M, Kralj P, Knezević T, Barać-Juretić K, Zgaga L., Common variant in myocilin gene is associated with high myopia in isolated population of Korcula Island, Croatia., Croatian Medical Journal, 50, (1), 2009, p17-22
Pulanić D, Polasek O, Petrovecki M, Vorko-Jović A, Pericić M, Lauc LB, Klarić IM, Biloglav Z, Kolcić I, Zgaga L, Carothers AD, Ramić S, Setić M, Janićijević B, Narancić NS, Bućan K, Rudan D, Lowe G, Rumley A, Rudan P, Campbell H, Rudan I., Effects of isolation and inbreeding on human quantitative traits: an example of biochemical markers of hemostasis and inflammation., Human Biology, 80, (5), 2008, p513-33
Rudan I, Carothers AD, Polasek O, Hayward C, Vitart V, Biloglav Z, Kolcic I, Zgaga L, Ivankovic D, Vorko-Jovic A, Wilson JF, Weber JL, Hastie N, Wright A, Campbell H., Quantifying the increase in average human heterozygosity due to urbanisation., European Journal of Human Genetics, 16, (9), 2008, p1097-102
Zgaga L, Hayward C, Vatavuk Z, Bencic G, Zemunik T, Valkovic A, Valkovic-Antic I, Bucan K, Rudan I., High prevalence of glaucoma in Veli Brgud, Croatia, is caused by a dominantly inherited T377M mutation in the MYOC gene., British Journal of Ophthalmology, 92, (11), 2008, p1567-8
Vitart V, Rudan I, Hayward C, Gray NK, Floyd J, Palmer CN, Knott SA, Kolcic I, Polasek O, Graessler J, Wilson JF, Marinaki A, Riches PL, Shu X, Janicijevic B, Smolej-Narancic N, Gorgoni B, Morgan J, Campbell S, Biloglav Z, Barac-Lauc L, Pericic M, Klaric IM, Zgaga L, Skaric-Juric T, Wild SH, Richardson WA, Hohenstein P, Kimber CH, Tenesa A, Donnelly LA, Fairbanks LD, Aringer M, McKeigue PM, Ralston SH, Morris AD, Rudan P, Hastie ND, Campbell H, Wright AF., SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout., Nature Genetics, 40, (4), 2008, p437-42
Kerkeni E, Monastiri K, Saket B, Rudan D, Zgaga L, Ben Cheikh H., Association among education level, occupation status, and consanguinity in Tunisia and Croatia., Croatian Medical Journal, 47, (4), 2006, p656-61
Saftić V, Rudan D, Zgaga L., Mendelian diseases and conditions in Croatian island populations: historic records and new insights., Croatian Medical Journal, 47, (4), 2006, p543-52
Non-Peer-Reviewed Publications
Zgaga L, Heterogeneity of the Effect of Vitamin D Supplementation in Randomized Controlled Trials on Cancer Prevention. , JAMA Netw Open, 3, (11), 2020, pe2027176
Lina Zgaga, Vitamin D, BONE HEALTH & OSTEOPOROSIS CONFERENCE, April 2019, 2019
Lina Zgaga, Causality in Vitamin D assessment, Irish Osteoporosis Society Annual Medical Conference, Dublin, October, 2019
L Zgaga, F O'Sullivan, J van Geffen, M van Weele , ANNUAL AMBIENT UVB AT A PLACE OF RESIDENCE AND RISK OF BREAST, COLORECTAL, LUNG AND PROSTATE CANCER: A LARGE PROSPECTIVE COHORT STUDY., Vitamin D Workshop, Barcelona, Spain, 2018
Zgaga L, Vaughan-Shaw PG, O'Sullivan F, Farrington SM, Theodoratou E, Campbell H, Dunlop MG., Reply to 'Comment on 'The impact of vitamin D pathway genetic variation and circulating 25-hydroxyvitamin D on cancer outcome: systematic review and meta-analysis''., Br J Cancer. , 117, (2), 2017, pe4.
Lina Zgaga, Genetics and Vitamin D, Irish Osteoporosis Society Annual Medical Conference, Dublin, Ireland, 2016
Lina Zgaga, Effects of Vitamin D deficiency on human health - not just a problem for bones? , 2nd Annual Multidisciplinary Study Day in Metabolic Bone Biochemistry and Medicine , Dublin, Ireland, 4th March, 2016
Zgaga L, Rudan I., Schizophrenia: Searching for the causes through many layers of complexity., Psychiatria Danubina, 24, (1), 2012, p21-2
Najznačajnije grane epidemiologije [Branches of Epidemiology; in Croatian]. in, editor(s)Ivana Kolcic, Ariana Vorko-Jovic. , Epidemiologija [Epidemiology; in Croatian]. , Zagreb, Croatia, Medicinska naklada, 2012, [Ivana Kolčić, Lina Zgaga, Ariana Znaor, Ira Gjenero-Margan]
Psihosomatske bolesti [Psychosomatic diseases; in Croatian]. in, editor(s)Dinko Puntarić, Darko Ropac, Arijana Vorko-Jović, Ira Gjenero-Margan, Igor Rudan. , Opća epidemiologija [General epidemiology; in Croatian]. , Zagreb, Croatia, LASERplus, 2007, [Lina Zgaga]
Research Expertise
Projects
- Title
- SOGVID: Survival in Oesophageal and Gastric Cancer Patients and Vitamin D
- Funding Agency
- European Commission
- Title
- Integrative genomics in colorectal cancer susceptibility: developing risk reducing interventions through understanding biology
- Funding Agency
- CRUK
- Title
- Growing Up in Ireland Phase 2
- Funding Agency
- Department of Children and Youth Affairs
- Title
- The development of a well-being index and identification of major disruptors of well-being in Irish children
- Funding Agency
- National Children's Research Center, Ireland
Recognition
Representations
The National Research Ethics Committee, Member (Ministerial Appointment)
Editorial Board Member (Nutrients)
The Irish Expert Body on Fluorides and Health, Member (Ministerial Appointment)
Management Team Member for Growing up in Ireland Study
Scientific Advisory Group for the Growing Up in Ireland Study, Member
Editorial Board Member (Nutrients)
The St. James' Hospital and Tallaght University Hospital Joint Research Ethics Committee, JREC, level 3, member
External Examiner (PhD proposal reviewer, The University of Southern Denmark, The Graduate School of Health Sciences, Denmark)
External Examiner (PhD, University of Edinburgh)
External Evaluator for Senior Academic Promotion (University of Haifa)
Progress Review Panel, member for the SFI Centre for Research Training in Genomics Data Science
Grant reviewer (Medical Research Council, New Investigator Research Grants (NIRG) stream)
Grant reviewer (COST Association, European Cooperation in Science and Technology)
Grant reviewer (Croatian National Science Foundation)
Journal Reviewer for top-of-the-class journals, including: British Medical Journal (BMJ); Journal of the National Cancer Institute (JNCI); European Journal of Epidemiology; Environmental Health Perspectives; International Journal of Cancer; Journal of Nutrition; Nutrients; PLoS Genetics; PLoS Medicine, and many other).
Editorial Board Member (Endocrine Oncology and Metabolism Journal)
Editorial Board Member (Journal of Global Health)
Provision of expert advice to the government bodies on Medically Assisted Reproduction Act (Croatia)
Awards and Honours
Athena SWAN Bronze Award for the School of Medicine (Committee Chair and Athena SWAN Champion)
Fellow of Trinity College Dublin
Provost's Research Award (Provost's PhD Projects)
Provost's Teaching Award
Article selected as the "Editor's Pick" (Journal of Nutrition, Q1)
Platform Presentation Prize Winner (Irish Society of Gastroenterology Summer Meeting)
Award for outstanding scientific productivity during PhD
Douglas Falconer Prize for best MSc dissertation
MSc degree in genetics with distinction
Grade Point Average in Medical School: 4.83 / 5.00; among top 5% of the class
Memberships
The National Research Ethics Committee (NREC)
The St. James' Hospital and Tallaght University Hospital Joint Research Ethics Committee (JREC)
The Irish Expert Body on Fluorides and Health (member)
HRB Trials Methodology Research Network member and TCD lead
Croatian Medical Association