Professor Alan Irvine
PROFESSOR OF DERMATOLOGY, Clinical Medicine
PROFESSOR OF DERMATOLOGY, School Office - Medicine
Biography
I am a physician scientist and health system leader passionate about driving innovation to improve the lives of people living with atopic dermatitis, vascular anomalies, and rare genetic skin diseases. A Clarivate Highly Cited Researcher, I have co-authored more than 400 scientific publications and multiple US patents. My work spans disease mechanisms, translational medicine, and drug development, with a focus on turning scientific insight into meaningful patient impact. I have advised over 50 biotechnology and pharmaceutical companies across the full development pathway, from early discovery to late-stage trials and regulatory strategy, and regularly advise life science investors. My commitment to better patient outcomes extends beyond research through leadership roles as Founding Director of the Irish Skin Foundation and Founding Director (and current President) of the International Eczema Council. As President of the Irish Hospital Consultants Association, I served as lead negotiator representing almost 5,000 consultants in discussions with the Irish Government on the 2023 Public Consultant Contract.
Publications and Further Research Outputs
Peer-Reviewed Publications
Silverberg J.I., Prajapati V.H., Abraham S., Irvine A.D., Gooderham M.J., Guttman-Yassky E., Tanizaki H., Rademaker M., Chen S.H., Moreira A., Ta R., Lee W.-J., Eyerich K., Achieving Minimal Disease Activity in Atopic Dermatitis Is Associated with Fewer Flares, Reduced Healthcare Resource Utilization, and Improved Disease Control: Analysis from the Real-World MEASURE-AD Study, Dermatology and Therapy, 16, (9), 2026, p4617 - 4630, p4617-4630
Weidinger S., Aoiki V., Dhar S., Dlova N.C., Kabashima K., Ma L., Flohr C., Irvine A.D., Atopic dermatitis, Nature Reviews Disease Primers, 12, (1), 2026
Wu H.L.A., Le Floch P., Duverdier A., Irvine A.D., Dubrac S., Tanaka R.J., Current research landscape and future prospects of in silico modeling approaches for atopic dermatitis, JID Innovations, 6, (5), 2026
Guttman-Yassky E., Irvine A.D., Gooderham M., Weidinger S., Spelman L., Silverberg J.I., Crane H., ElMaraghy H., DeLuca-Carter L., Piruzeli M.L.B., Martimianaki G., Pierce E., Agell H., Thaci D., Three-Year Efficacy and Safety of Lebrikizumab in Patients with Moderate-to-Severe Atopic Dermatitis: A Long-Term Extension (ADjoin), Dermatology and Therapy, 16, (8), 2026, p4021 - 4039, p4021-4039
Ruge I.F., Nielsen M.-L., Halling A.S., Gerner T., Rinnov M.R., Trautner S., Thomsen S.F., Skov L., Egeberg A., Jakasa I., Kezic S., Irvine A.D., Guttman-Yassky E., Bonnelykke K., Thyssen J.P., Preterm birth is associated with reduced risk of atopic dermatitis and a distinct allergic comorbidity profile in early childhood, British Journal of Dermatology, 195, (3), 2026, p496 - 505, p496-505
Zhiyong Zheng, Manon Dechêne-Tempier, Telmo O. Paiva, Can Wang, Sophie Dunn, Julianne Clowry, Alan D. Irvine, Joan A. Geoghegan, Yves Dufrêne, Nanoscale Mechanics of FnBPB-Mediated Adhesion of Staphylococcus aureus to Skin Ligands, ACS Nano, 20, (8), 2026, p7279 - 7290, p7279-7290
Victor Grentzinger, Maria Artesi, Léonor Palmeira, Nathalie Renotte, Nadine Cambisano, Vinciane Dideberg, Laura Helou, Benoît Charloteaux, Bita Dezfoulian, Gilles Absil, Justine Pètre, Murielle Sabatiello, Colombine Meunier, W.H. Irwin McLean, Aileen Sandilands, Maeve A. McAleer, Alan D. Irvine, Annette Uwineza, Alice Amani Uwajeni, Sabine Olivier, Keith Durkin, Vincent Bours, Long Read Sequencing of Filaggrin identifies extensive copy number variation in exon 3 and detects rare loss of function variants, JID Innovations, 2026, p100522 - 100522, p100522-100522
Silverberg J.I., Irvine A.D., Foley P., Del Rosso J., Puig L., Stein Gold L., Kamata M., Wollenberg A., Hong H.C.-H., Chu C.-Y., Binamer Y., Dossenbach M., Casillas M., Gallo G., Akmaz B., Rand K., Chovatiya R., A Durability Index for Atopic Dermatitis: Indirect Comparison of Lebrikizumab, Dupilumab, and Tralokinumab in Maintaining Efficacy Under Variable Treatment Adherence, Dermatology and Therapy, 16, (8), 2026, p4001 - 4020, p4001-4020
Tiago Torres, N. C. Brembilla, B. King, Raj Chovatiya, Ruth Warren, Carsten Flohr, C. Vestergaard, Alan D. Irvine, J.M. Carrascosa, Julia"Tatjana Maul, Catherine Smith, R.G. Langley, J. Cortés, V. Sibaud, D. Thaçi, W. H. Boehncke, P. Spuls, L. Puig, Targeted therapies for psoriasis and atopic dermatitis in the context of malignancy: SPIN " FRT recommendations, Journal of the European Academy of Dermatology and Venereology, 2026
Lv K., Forde K.M., Moon A.T., Zhang Z., Pang L., Nomakuchi T.T., Zhao S., Murrell J.R., Wood K.H., Irvine A.D., Gray C., Lin Z., Wang H., Loss-of-function variants in EPHX3 cause nonsyndromic epidermal differentiation disorders, British Journal of Dermatology, 195, (3), 2026, p473 - 482, p473-482
Amy S. Paller, Alan D. Irvine, Eulàlia Baselga, Marlies de Graaf, Elaine C. Siegfried, Michael J. Cork, Michele Ramien, Lawrence F. Eichenfield, Bryan Adams, Rajan Gupta, Marius Ardeleanu, Annie Zhang, Growth Assessment in Children Under 12 Years With Moderate"to"Severe Atopic Dermatitis Included in the PEDISTAD Observational Registry, Pediatric Dermatology, 2026
Chivardi C., Gribaleva E., Coker B., Tsoi M.F., Carroll R., Prieto Merino D., Baden M., Beattie P.E., Brown S.J., Burton T., Hearn R., Ingram J.R., Irvine A.D., Johnston G.A., Man I., Ogg G., Wan M., Warren R.B., Woolf R.T., Reynolds N.J., Ardern-Jones M.R., Flohr C., Manca A., Ali M., Ardern-Jones M.R., Baldago J., Bale T., Beattie P.E., Brown S.J., Brown V., Cork M.J., Chua S.-L., Darne S., Fahy C., Ferguson L., Flohr C., Hearn R., Housam N., Ingram J.R., Johnston G.A., Ladoyanni E., Layton A., Leitch C., Simpson R., Man I., Moffit D., Newell L., Searle J., Paget S., Petrof G., Popli U., Rennie C., Reynolds N.J., Rouhani N., Sergeant A., Thompson B., Wahie S., Warren R.B., Weller R., Wernham A., Woolf R.T., Healthcare resource use, costs and health-related quality of life in the UK"Irish Atopic eczema Systemic Therapy Register (A-STAR): a pilot study, Skin Health and Disease, 6, (4), 2026, p459 - 467, p459-467
Irvine A.D., Paller A.S., Siegfried E.C., Cork M.J., Beck L.A., Eichenfield L.F., Swanson L., Hamon S.C., Horowitz J.E., Farrell A.B., Hatsell S., Zhang A., Bansal A., You X., Chen Z., Levy S., Cyr S.L., Dupilumab treatment improves linear growth and bone biomarkers in children with atopic dermatitis: Post hoc analysis of a phase 3 randomized, placebo-controlled clinical trial and an open-label extension study, Journal of the American Academy of Dermatology, 95, (5), 2026, p1324 - 1334, p1324-1334
Stephan Weidinger, Valeria Aoiki, Sandipan Dhar, Ncoza C. Dlova, Kenji Kabashima, Lin Ma, Carsten Flohr, Alan D. Irvine, Atopic dermatitis, Nature Reviews Disease Primers, 12, (1), 2026
Hiu Lam Athena Wu, Pierre Le Floch, Ariane Duverdier, Alan D. Irvine, Sandrine Dubrac, Reiko Tanaka, Current research landscape and future prospects of in silico modeling approaches for atopic dermatitis, JID Innovations, 6, (5), 2026, p100513 - 100513, p100513-100513
Cristina Grechin, Alan D. Irvine, Natasha Jordan, Niamh Leonard, Talulla Dunne, Bairbre Wynne, Pachydermoperiostosis: a mimicker of inflammatory arthritis, Clinical and Experimental Dermatology, 2026
Musters, A.H., Gerbens, L.A.A., van der Gang, L., Middelkamp-Hup, M.A., Ouwerkerk, W., Hijnen, D.J., Haufe, E., Heinrich, L., Werfel, T., Weidinger, S., Schmitt, J., Svedbom, A., Johansson, E.K., Bradley, M., von Kobyletzki, L.B., Vittrup, I., Ruge, I.F., Thyssen, J.P., Vestergaard, C., Carrascosa, J.M., de Vega, M., García-Doval, I., Chiricozzi, A., Stingeni, L., Calzavara-Pinton, P., Ardern-Jones, M.R., Reynolds, N.J., Flohr, C., Spuls, P.I., Bosma, A., Caron, A., Hyseni, A., Dijkstra, J., Nguyen, L., De Schepper, S., Lapeere, H., De Waele, D., Beattie, P., Brown, S., Burton, T., Ingram, J., Irvine, A., Johnston, G., Man, I., Manca, A., Ogg, G., Patton, T., Wan, M., Warren, R., Woolf, R., Baden, M., Prieto-Merino, D., Malik, R., Coker, B., De La Cruz, L., Gribaleva, E., Begum, T., Descalzo, M.A., Flórez, Á., Arnau, A.M.G., Quesada, A.G., Silvestre, J.F., Serna, M.R., Chicharro, P., Gilaberte, Y., de la Cueva, P., Montero, T., González, M.E., Villaverde, R.R., Rodríguez, J.J.P., Cebey, A.B., Arias, M.E., Rodríguez, C.C., Curto, L., Bertolín, M., Castaño, I., Betlloch, I., Pérez, M.A.L., Pérez, J.A.S., Ruiz, A.B., Munera, M., Arias-Santiago, S., Roustan, G., de la Torre, R.S., Diaz, A.R., Carrascosa, J.C.R., Navarro Triviño, F.J., Elberling, J., Skov, L., Ibler, K., Jemec, G., Möertz, C., Bindslev-Jensen, C., Kamstrup, M., Egeberg, A., Deleuran, M., Alsterholm, M., Anderson, C.D., Bradley, M., Sommar, L.H., Ivert, L., Johansson, E.K., Josefson, A., Lundeberg, L., Lundqvist, M., Nylander, E., Sandström-Falk, M., Shayesteh, A., Sigurdardottir, G., Sonesson, A., Svedbom, A., Svensson, Å., Virtanen, M., von Kobyletzki, L., Vrang, S., Wahlgren, C.-F., Corazza, M., Esposito, M., Fabbrocini, G., Fargnoli, M.C., Ferrucci, S.M., Foti, C., Girolomoni, G., Hansel, K., Marzano, A.V., Napolitano, M., Passante, M., Patruno, C., Peris, K., Pigatto, P.D., Romanelli, M., Romita, P., Rossi, M., Schena, D., Schettini, N., Tonini, G., Baseline characteristics of atopic eczema patients enrolled in seven European registries united in the TREatment of ATopic eczema (TREAT) registry taskforce, Journal of the European Academy of Dermatology and Venereology, 39, (12), 2025, p2096-2112
Kuan"Yu Chen, Alan D. Irvine, Jenna J. Lullo, Linda K. Martin, Julia"Tatjana Maul, Bibiana Pérez, David Rosmarin, J. Sansom, Brittney Schultz, Alexa R. Shipman, Nanette B. Silverberg, Zsuzsanna Szalai, Annamária Fodor, Anber Ancel Tanaka, Kate V. Viola, Raja K. Sivamani, Jenny E Murase, Ajay S. Dulai, Emi M. Murase, Gianluca Avallone, Silvia Mariel Ferrucci, Angelo Valerio Marzano, Simone Ribero, Michael R. Ardern"Jones, Emily Ko, Carsten Flohr, Yael A. Leshem, Mette Deleuran, Christian Vestergaard, DirkJan Hijnen, Juliëtte Bras, Scott A. Elman, Sara Pruneddu, Daniel Butler, Raj Chovatiya, Giampiero Girolomoni, Alexandra Golant, Marijke Kamsteeg, Paula Carolina Luna, Dédée F. Murrell, Madeleine Stark, Tiago Torres, Elif Afacan Yildrim, S. Aractingi, Christine Bangert, R.J. Batchelor, International multicenter case series of gestational dupilumab exposure in the treatment of atopic dermatitis: Maternal complications and fetal outcomes, Journal of the American Academy of Dermatology, 94, (3), 2025, p936 - 940, p936-940
Amy S. Paller, Lawrence F. Eichenfield, Alan D. Irvine, Carsten Flohr, Andreas Wollenberg, S. Barbarot, Christine Bangert, Jonathan M. Spergel, Andrew Selfridge, Pinaki Biswas, Haiyun Fan, Justine Alderfer, Melissa Watkins, Herwig Koppensteiner, Integrated Efficacy and Safety Analysis of Abrocitinib in Adolescents With Moderate"to"Severe Atopic Dermatitis, Allergy, 80, (8), 2025, p2213 - 2224, p2213-2224
Irene Lara"Corrales, Michele Ramien, Alan D. Irvine, Lin Ma, Danielle Marcoux, Eulàlia Baselga, Marlies de Graaf, Lara Wine Lee, Joel C. Joyce, Korey Capozza, Rajan Gupta, Marius Ardeleanu, Annie Zhang, 106: Dupilumab Significantly Improves Patient-Reported Outcomes in Patients Aged Under 12 Years With Atopic Dermatitis: 4-Year Results From the PEDISTAD Registry, Journal of Investigative Dermatology, 145, (3), 2025, pe26 - e26, pe26-e26
Linda Stein Gold, Eric L. Simpson, Diamant Thaçi, Alan D. Irvine, Marjolein de Bruin"Weller, Gaia Gallo, Maria Lucia Buziqui Piruzeli, Hany Elmaraghy, Jinglin Zhong, Sonia Montmayeur, Ruth Coll, Mark Lebwohl, Lebrikizumab Confirms a Consistent Safety Profile in Adults and Adolescents With Moderate-to-Severe Atopic Dermatitis: Data From 11 Trials With Over 3000 Patient-Years of Exposure, SKIN The Journal of Cutaneous Medicine, 9, (1), 2025, ps511 - s511, ps511-s511
Georgios N. Stamatas, Richard A. Insel, Nikolaj Sørensen, Albert Pallejá, Janne Marie Moll, Thierry Oddos, Carol ní Chaoimh, Jonathan O"B Hourihane, Alan D. Irvine, Shifts in Infant Skin Microbiome at 2 Months after Short-Term Emollient Use from Birth Are Associated with Reduced Prevalence of Atopic Dermatitis at 12 Months in a High-Risk Cohort, Journal of Investigative Dermatology, 145, (10), 2025, p2640 - 2643.e11, p2640-2643.e11
Janna Nousbeck, Maeve A. McAleer, Elaine Kenny, Alan D. Irvine, Effect of Topical Corticosteroid Treatment on microRNA Expression in Infants with Atopic Dermatitis, JID Innovations, 5, (5), 2025, p100388 - 100388, p100388-100388
Marjolein de Bruin"Weller, Celeste M. Boesjes, Roselie Achten, Lisa A. Beck, Alan D. Irvine, Christian Vestergaard, Marlies de Graaf, Femke van Wijk, Daphne S. Bakker, Stephan Weidinger, Biologics to Treat Atopic Dermatitis: Effectiveness, Safety, and Future Directions, Allergy, 81, (2), 2025, p326 - 344, p326-344
Standl, M., Budu-Aggrey, A., Johnston, L.J., Elias, M.S., Arshad, S.H., Bager, P., Bataille, V., Blakeway, H., Bonnelykke, K., Boomsma, D., Brumpton, B.M., Pineda, M.B., Campbell, A., Curtin, J.A., Eliasen, A., Fadista, J.P.S., Feenstra, B., Gerner, T., Gomez, C.M., Grosche, S., Gutzkow, K.B., Halling, A.-S., Hayward, C., Henderson, J., Herrera-Luis, E., Holloway, J.W., Hottenga, J., Hourihane, J.O.B., Hu, C., Hveem, K., Irizar, A., Jacquemi, B., Jessen, L., Kress, S., Kurukulaaratchy, R.J., Lau, S., Llop, S., Løset, M., Marenholtz, I., Mason, D., McCartney, D.L., Melbye, M., Melén, E., Minica, C., Murray, C.S., Nijsten, T., Pardo, L.M., Pasmans, S., Pennell, C.E., Rinnov, M.R., Santorelli, G., Schikowski, T., Sheehan, D., Simpson, A., Söderhäll, C., Thomas, L.F., Thyssen, J.P., Torrent, M., van Beijsterveldt, T., Visconti, A., Vonk, J.M., Wang, C.A., Xu, C.-J., Ziyab, A.H., Custovic, A., Di Meglio, P., Duijts, L., Flohr, C., Irvine, A.D., Koppelman, G.H., Lee, Y.-A., Reynolds, N.J., Smith, C., Langan, S.M., Paternoster, L., Brown, S.J., Gene-environment interaction analysis in atopic eczema: evidence from large population datasets and modelling in vitro, Medrxiv, 2025
Linda Stein Gold, Alan D. Irvine, William Romero, Hernán Valdez, Haiyun Fan, Justine Alderfer, Michael J. Cork, Mette Deleuran, Bob Geng, Jonathan I. Silverberg, Eric L. Simpson, Long-Term Safety of Abrocitinib in Moderate-to-Severe Atopic Dermatitis: Integrated Analysis by Age, The Journal of Allergy and Clinical Immunology In Practice, 13, (5), 2025, p1164 - 1175.e2, p1164-1175.e2
Eric L. Simpson, Alan D. Irvine, Jonathan I. Silverberg, Linda Stein Gold, Michael J. Cork, Mette Deleuran, Bob Geng, Cristina Lumpan, Haiyun Fan, Herwig Koppensteiner, Andrew Selfridge, 64775 Integrated Safety Update of Abrocitinib in 1014 Young Adult Patients Aged 18 to <40 Years With Moderate-to-Severe Atopic Dermatitis: Data From More Than 2250 Patient-Years With up to 4.5 Years of Exposure, Journal of the American Academy of Dermatology, 93, (3), 2025, pAB234 - AB234, pAB234-AB234
Jonathan I. Silverberg, Vivian Laquer, Peter Lio, Kim Papp, Alan D. Irvine, Andrew Blauvelt, Hany Elmaraghy, Louise DeLuca-Carter, Heidi M. Crane, Gaia Gallo, Evangeline Pierce, Yuxin Ding, Amy S. Paller, Lucia Seminario"Vidal, 361 Lebrikizumab Dosed Every 8 Weeks as Maintenance Provides Long-Lasting Response in Patients with Moderate-to-Severe Atopic Dermatitis, Journal of Investigative Dermatology, 145, (11), 2025, pe88 - e88, pe88-e88
Gerwin J. Puppels, Jonathan O'B. Hourihane, Claudio Nico, Carol Ni Chaoimh, Colin Wong, John E. Common, Peter J. Caspers, Alan D. Irvine, Highly accurate, noninvasive early identification of infants with a filaggrin loss-of-function mutation by in vivo Raman spectroscopy, followed from birth to 12 months, Annals of Allergy Asthma & Immunology, 134, (4), 2025, p457 - 464, p457-464
Jonathan I. Silverberg, Alan D. Irvine, Peter Foley, J.Q. Del Rosso, L. Puig, Linda Stein Gold, M. Dossenbach, Marta Casillas, Gaia Gallo, Bülent Akmaz, Kim Rand, Comparative Efficacy of Lebrikizumab, Dupilumab, and Tralokinumab in Maintaining Treatment Response in Atopic Dermatitis at Varying Treatment Continuance Rates, SKIN The Journal of Cutaneous Medicine, 9, (1), 2025, ps519 - s519, ps519-s519
Christopher G. Bunick, Alan D. Irvine, Jonathan I. Silverberg, Emma Guttman"Yassky, Mona Shahriari, Xing"Hua Gao, Stephan Weidinger, Norito Katoh, Namita Vigna, Deanne M. Dilley, Elvira D"Andrea, Henrique D. Teixeira, Andrew M. Platt, Gweneth F. Levy, Safety of upadacitinib in atopic dermatitis in randomized clinical trials across 6 years, Journal of the European Academy of Dermatology and Venereology, 40, (5), 2025, p856 - 866, p856-866
Gerd R Burmester, Atul Deodhar, Alan D. Irvine, Remo Panaccione, Kevin Winthrop, Ruth Ann Vleugels, Gweneth Levy, Smitha Suravaram, Hannah Palac, Lani R. Wegrzyn, Sharanya Ford, Sebastian Meerwein, Emma Guttman"Yassky, Safety Profile of Upadacitinib: Descriptive Analysis in Over 27,000 Patient-Years Across Rheumatoid Arthritis, Psoriatic Arthritis, Axial Spondyloarthritis, Atopic Dermatitis, and Inflammatory Bowel Disease, Advances in Therapy, 42, (10), 2025, p5215 - 5237, p5215-5237
Fiona Lynch, Alan D. Irvine, Disproportionality analysis highlights paradoxical psoriasis as a clinically significant class effect of tumor necrosis-" inhibitors in pediatric populations, Pediatric Research, 99, (3), 2025, p837 - 838, p837-838
Amy S. Paller, Alan D. Irvine, Elaine C. Siegfried, Michael J. Cork, Lin Ma, Wenying Deng, Stephane Levy, Mike Bastian, Sonya Cyr, 141 Exploration of Bone Formation-Like Biomarker in Pediatric Patients Aged 2 to 17 Years With Atopic Dermatitis Treated With Dupilumab, Journal of Investigative Dermatology, 145, (11), 2025, pe54 - e54, pe54-e54
Alan D. Irvine, Amy S. Paller, Elaine C. Siegfried, Michael J. Cork, Lisa A. Beck, Zhen Chen, C. Peralta, Annie Zhang, Stephane Levy, Sonya Cyr, 62057 Growth Analysis in Children 6-11 Years with Severe Atopic Dermatitis and Impact of up to 52 Weeks of Dupilumab on Height, Journal of the American Academy of Dermatology, 93, (3), 2025, pAB49 - AB49, pAB49-AB49
Guttman-Yassky, E., Irvine, A., Simpson, E., Gooderham, M., Weidinger, S., Spelman, L., Silverberg, J., Crane, H., Elmaraghy, H., Deluca-Carter, L., Piruzeli, M.L.B., Hu, C., Pierce, E., Agell, H., Thaçi, D., Long-Term Efficacy and Safety of Lebrikizumab Is Maintained in Patients With Moderate-to-Severe Atopic Dermatitis: Results Up to 3 Years From ADjoin, Skin Journal of Cutaneous Medicine, 9, (1), 2025, ps510
Elizaveta Gribaleva, Niels Steen Krogh, David Prieto-Merino, Bolaji Coker, Abaigeal Jackson, Ahmet Akkoç, Thomas Birkner, Erwin Bruninx, Con Hennessy, K.T. Chan, Lara Cutlar, Byron Farrell, G. Fletcher, Louise A. A. Gerbens, Anne Grete Frøstrup, Dan Henrohn, Ariënna Hyseni, Alan D. Irvine, Rayka Malek, Caitriona McCarthy, Ida Vittrup, Wouter Ouwerkerk, Rowena Randall, Phyllis I. Spuls, Simon Francis Thomsen, Dmitri Wall, Stephan Weidinger, Thomas Werfel, Jochen Schmitt, Carsten Flohr, A pan-European register-based observational study of abrocitinib and conventional systemic therapies in moderate and severe atopic dermatitis: the DREAM TO TREAT AD study protocol, Skin Health and Disease, 5, (3), 2025, p196 - 202, p196-202
Iben Frier Ruge, Anne"Sofie Halling, Maria Rasmussen Rinnov, Trine Gerner, Mette Hjorslev Knudgaard, Nina Haarup Ravn, Mia"Louise Nielsen, Lone Skov, Simon Trautner, Simon Francis Thomsen, Alexander Egeberg, Ivone Jakaša, Alan D. Irvine, Sanja Keži", Jacob P. Thyssen, Infant palmar hyperlinearity and type 2 inflammatory markers predict atopic dermatitis at 1 year of age, Journal of the European Academy of Dermatology and Venereology, 39, (12), 2025, p2079 - 2087, p2079-2087
Jonathan I. Silverberg, Vivian Laquer, Peter Lio, Kim Papp, Alan D. Irvine, Andrew Blauvelt, Hany Elmaraghy, Louise DeLuca-Carter, Gaia Gallo, Evangeline Pierce, Yuxin Ding, Amy S. Paller, Heidi M. Crane, Lebrikizumab Dosed Every 8 Weeks as Maintenance Provides Long-Lasting Response in Patients with Moderate-to-Severe Atopic Dermatitis, SKIN The Journal of Cutaneous Medicine, 9, (6), 2025, ps601 - s601, ps601-s601
Grechin C, SLCO2A1 Genetic Analysis Unravelled the Puzzle. A case of Pachydermoperiostosis in an Adolescent Male, Clinical and Experimental Dermatology, 2025
Bob Geng, Vinay Mehta, Amy S. Paller, Ama Alexis, Alan D. Irvine, Carsten Flohr, Antonio Torello, Zach Dawson, Evangeline Pierce, Helena Agell, Hong Zhang, Meihua Qiao, Mark Boguniewicz, Lebrikizumab Improves Anxiety and Depression Symptoms of Adolescents with Moderate-to-Severe Atopic Dermatitis: Results from a 52-Week, Open-label, Phase 3 Study, Journal of Allergy and Clinical Immunology, 155, (2), 2025, pAB200 - AB200, pAB200-AB200
Lisa A. Beck, Amy S. Paller, Elaine C. Siegfried, Lawrence F. Eichenfield, Alan D. Irvine, Eric L. Simpson, Eulàlia Baselga, Peter Lio, Ana B. Rossi, J Lyu, Sonya Cyr, 64623 Dupilumab Treatment Significantly Reduces Age-Dependent Total IgE Levels in Young Children With Atopic Dermatitis, Journal of the American Academy of Dermatology, 93, (3), 2025, pAB179 - AB179, pAB179-AB179
Blokhuis C, Leahy TR, Irvine AD, Browne F, Flinn AM., Baricitinib-Induced Remission of Alopecia Universalis in a Child with NFKB2-Associated Immune Dysregulation., Journal of clinical immunology, 45, (1), 2025, p62
Alan D. Irvine, Amy S. Paller, Elaine C. Siegfried, Michael J. Cork, Lisa A. Beck, Zhen Chen, C. Peralta, Annie Zhang, Stephane Levy, Sonya Cyr, Growth Analysis in Children Aged 6 to 11 Years and Adolescents Aged 12 to 17 Years With Moderate-To-Severe Atopic Dermatitis and Impact of 16 Weeks of Dupilumab Treatment on Height, Journal of Allergy and Clinical Immunology, 155, (2), 2025, pAB208 - AB208, pAB208-AB208
Aoife Hollywood, Olga Tummon, Maeve A. McAleer, Suzanne Kelleher, Alan D. Irvine, Telangiectasia in the Distribution of the Superior Vena Cava: A Novel Dermatological Manifestation of 22q11.2 Deletion Syndrome, Pediatric Dermatology, 43, (1), 2025, p109 - 112, p109-112
Constance Chantraine, Priscila da Silva Figueiredo Celestino Gomes, Marion Mathelié"Guinlet, Diego E. B. Gomes, Zhiyong Zheng, Julianne Clowry, Mary B. Turley, Alan D. Irvine, Joan A. Geoghegan, Rafael C. Bernardi, Yves F. Dufrêne, Ultrastrong Staphylococcus aureus adhesion to human skin: Calcium as a key regulator of noncovalent interactions, Science Advances, 11, (36), 2025, peadu7457 - eadu7457, peadu7457-eadu7457
Katie Ridge, Rizwan Ahmad, Barry Moran, Cliona O"Farrelly, Jean Dunne, Conor M. Finlay, Alan D. Irvine, Niall Conlon, Towards Personalised Therapy in Chronic Spontaneous Urticaria: Advancing From Endotype to Clinical Response, Clinical & Experimental Allergy, 55, (11), 2025, p1070 - 1082, p1070-1082
Monica Arenas-Hernandez, Anna Rosala"Hallas, Paula Beattie, Susannah Baron, Fiona Browne, Sara Brown, J. E. Gach, Danielle Greenblatt, Ross Hearn, Eva Hilger, Ben Esdaile, Michael J. Cork, Emma Howard, Marie"Louise Lovgren, Suzannah August, Farhiya Ashoor, Paula Williamson, Tess McPherson, Donal O"Kane, Jane Ravenscroft, Lindsay Shaw, Manish D. Sinha, Catherine Spowart, Bjorn Thomas, Tracey Sach, Alan D. Irvine, Carsten Flohr, Mandy Wan, Ashley P Jones, Daniel K. Maskrey, Exposure"response of ciclosporin and methotrexate in children and young people with severe atopic dermatitis: a secondary analysis of the TREatment of severe Atopic dermatitis Trial (TREAT), Clinical and Experimental Dermatology, 50, (8), 2025, p1623 - 1627, p1623-1627
Emma Guttman"Yassky, Stephan Weidinger, Eric L. Simpson, Melinda Gooderham, Alan D. Irvine, Lynda Spelman, Jonathan I. Silverberg, Hany Elmaraghy, Louise DeLuca-Carter, Maria Lucia Buziqui Piruzeli, Chaoran Hu, Fan Emily Yang, Evangeline Pierce, Laia Bardolet, Diamant Thaçi, Two-Year Efficacy and Safety of Lebrikizumab in Patients with Moderate-to-Severe Atopic Dermatitis: A Long-Term Extension (ADjoin), Dermatology and Therapy, 15, (8), 2025, p2217 - 2232, p2217-2232
Krogh, N.S., Prieto-Merino, D., Coker, B., Birkner, T., Akkoc, A., Gribaleva, E., Nielsen, I.V., Frostrup, A.G., Christensen, M.O., Thomsen, S.F., Irvine, A.D., Fletcher, G., Spuls, P.I., Hennessy, C., Farrell, B., Jackson, A., Guler, E., Bruninx, E., Cutlar, L., Gerbens, L.A.A., Henrohn, D., Hyseni, A., McCarthy, C., Ouwerkerk, W., Randall, R., Wall, D., Hertzschuch, A., Weidinger, S., Werfel, T., Schmitt, J., Flohr, C., Implementing Federated Analysis Using DataSHIELD in the DREAM TO TREAT Atopic Dermatitis Registries Collaboration, Journal of Investigative Dermatology, 2025
Tracey Sach, Ashley P Jones, Anna Rosala"Hallas, Catherine Spowart, Farhiya Ashoor, Alan D. Irvine, Paula Beattie, Susannah Baron, F. J. Browne, Mandy Wan, Amina Ahmed, Carsten Flohr, Methotrexate versus Ciclosporin in the Treatment of Severe Atopic Eczema in Children: An economic evaluation, Efficacy and Mechanism Evaluation, 2025, p1 - 27, p1-27
Katie Ridge, Barry Moran, Mark A. Little, Cliona O"Farrelly, Jean Dunne, Julianne Clowry, Clodagh Loftus, Conor M. Finlay, Alan D. Irvine, Niall Conlon, Myeloid and Mast Cell Progenitors Are Elevated in Atopic Dermatitis, JID Innovations, 5, (5), 2025, p100390 - 100390, p100390-100390
Puppels, G.J., Hourihane, J.O., Nico, C., Chaoimh, C.N., Wong, C., Common, J.E., Caspers, P.J., Irvine, A.D., Erratum to `Highly accurate, noninvasive early identification of infants with a filaggrin loss-of-function mutation by in vivo Raman spectroscopy, followed from birth to 12 months" [Annals of Allergy, Asthma & Immunology, 134;4 (2025) 457"464, (S1081120625000109), (10.1016/j.anai.2025.01.010)], Annals of Allergy Asthma and Immunology, 135, (1), 2025, p124
Diong, S., Gallagher, C., Clowry, J., Irvine, A.D., McAleer, M.A., Laser Hair Reduction to the Residuum Improves Quality of Life in People with Amputations, Journal of Clinical and Aesthetic Dermatology, 18, (12), 2025, p42-44
J. Lee, Hiu Lam Athena Wu, Ahmad A. Mannan, Yuumi Nakamura, Masayuki Amagai, Alan D. Irvine, Reiko Tanaka, Toward the Next Generation of In Silico Modeling of Dynamic Host-Microbiota Interactions in the Skin, JID Innovations, 5, (5), 2025, p100385 - 100385, p100385-100385
Iben Frier Ruge, Mia"Louise Nielsen, Anne"Sofie Halling, Trine Gerner, Maria Rasmussen Rinnov, Simon Trautner, Simon Francis Thomsen, Lone Skov, Alexander Egeberg, Ivone Jakaša, Sanja Keži", Alan D. Irvine, Emma Guttman"Yassky, Klaus Bønnelykke, Jacob P. Thyssen, Preterm Birth Is Associated With Reduced Risk of Atopic Dermatitis and Allergic Comorbidity in Early Childhood, 2025
Alan D. Irvine, A.S. Paller, E.S. Siegfried, Michael J. Cork, Lisa A. Beck, M.N. Crépy, J Lyu, A. Zhang, Stephane Levy, Sonya Cyr, Amélioration de la croissance chez les enfants de 6 à 11 ans atteints de dermatite atopique sévère traités par dupilumab, indépendamment de l"utilisation de corticostéroïdes topiques, Annales de Dermatologie et de Vénéréologie - FMC, 5, (8), 2025, pA386 - A387, pA386-A387
Marie Standl, Ashley Budu"Aggrey, Luke Johnston, Martina S. Elias, Syed Hasan Arshad, Peter Bager, Véronique Bataille, Helena Blakeway, Klaus Bønnelykke, Dorret I. Boomsma, Ben Brumpton, Mariona Bustamante, Archie Campbell, John A. Curtin, Anders Eliasen, João Fadista, Bjarke Feenstra, Trine Gerner, Carolina Medina"Gómez, Sarah Grosche, Kristine B. Gützkow, Anne"Sofie Halling, Caroline Hayward, John Henderson, Esther Herrera"Luis, John W. Holloway, Jouke"Jan Hottenga, Jonathan O"B Hourihane, Chen Hu, Kristian Hveem, Amaia Irizar, Bénédicte Jacquemin, Leon Eyrich Jessen, Sara Kress, Ramesh Kurukulaaratchy, Susanne Lau, Sabrina Llop, Mari Løset, Ingo Marenholz, Dan Mason, Daniel L. McCartney, Mads Melbye, Erik Melén, Camelia C. Minic", Clare Murray, Tamar Nijsten, Luba M. Pardo, Suzanne G.M.A. Pasmans, Craig E. Pennell, Maria Rasmussen Rinnov, Gillian Santorelli, Tamara Schikowski, Darina Sheehan, Angela Simpson, Cilla Söderhäll, Laurent F. Thomas, Jacob P. Thyssen, Maties Torrent, Toos van Beijsterveldt, Alessia Visconti, Judith M. Vonk, Carol A. Wang, Cheng"Jian Xu, Ali H. Ziyab, Adnan "ustovi", Paola Di Meglio, Liesbeth Duijts, Carsten Flohr, Alan D. Irvine, Gerard H. Koppelman, Young"Ae Lee, Nick J. Reynolds, Catherine Smith, Sinéad Langan, Lavinia Paternoster, Sara Brown, Gene"Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies, Allergy, 80, (8), 2025, p2201 - 2212, p2201-2212
Nekma Meah, Jane Li, Dmitri Wall, Katherine York, Bevin Bhoyrul, Laita Bokhari, Lachlan Coulthard, Leila Asfour, Leonardo Spagnol Abraham, Daniel Asz"Sigall, Wilma F. Bergfeld, Regina C. Betz, Ulrike Blume"Peytavi, Valerie Callender, Vijaya Chitreddy, Andrea Combalía, George Cotsarelis, Brittany G. Craiglow, Rachita Dhurat, Ncoza C. Dlova, Jeffrey Donovan, Andrei G. Doroshkevich, Samantha Eisman, Paul Farrant, Aida Gadzhigoroeva, Jack Green, Ramón Grimalt, Matthew Harries, Maria Hordinsky, Alan D. Irvine, Victoria Jolliffe, Spartak Kaiumov, Brett King, Steven Kossard, Joyce Lee, Won"Soo Lee, Nino Lortkipanidze, Amy McMichael, Natasha Atanaskova Mesinkovska, Andrew G. Messenger, Paradi Mirmirani, Elise A. Olsen, Seth J. Orlow, Yuliya Ovcharenko, Bianca Maria Piraccini, Rodrigo Pirmez, Adriana Rakowska, Pascal Reygagne, Janet L. Roberts, Lidia Rudnicka, David Saceda"Corralo, Jerry Shapiro, Pooja Sharma, Tatiana Silyuk, Poonkiat Suchonwanit, Anita Takwale, Antonellá Tosti, Willem I. Visser, Sérgio Vañó-Galván, Annika Vogt, Martin Wade, Leona Yip, Abraham Zlotogorski, Cheng Zhou, Rodney Sinclair, Statement from the frontal fibrosing alopecia international expert alliance: SOFFIA 2024, Journal of the European Academy of Dermatology and Venereology, 40, (2), 2025, p210 - 223, p210-223
Silverberg, J.I., Bieber, T., Paller, A.S., Beck, L., Kamata, M., Puig, L., Wiseman, M., Ezzedine, K., Irvine, A.D., Foley, P., Del Rosso, J., Gold, L.S., Johansson, E., Dossenbach, M., Gallo, G., Akmaz, B., Casillas, M., Karlsson, A., Curteis, T., Chovatiya, R., Lebrikizumab vs Other Systemic Monotherapies for Moderate-to-Severe Atopic Dermatitis: Network Meta-analysis of Efficacy, Dermatology and Therapy, 15, (3), 2025, p615-633
Eric L. Simpson, Alan D. Irvine, Jan Gutermuth, Chih-ho Hong, Raj Chovatiya, Emma Guttman"Yassky, Haiyun Fan, Gary Chan, Cristina Lumpan, Justine Alderfer, Herwig Koppensteiner, Integrated Safety Analysis of Abrocitinib in 3850 Patients With Moderate-To-Severe Atopic Dermatitis: Data From More Than 9600 Patient-Years With Up to 6.5 Years of Exposure, SKIN The Journal of Cutaneous Medicine, 9, (6), 2025, ps616 - s616, ps616-s616
Elizaveta Gribaleva, K.T. Chan, Carlos Chivardi, David Prieto"Merino, Man Fung Tsoi, Rebecca Carroll, Bolaji Coker, Lilia de la Cruz, Manisha Baden, Paula Beattie, Sara Brown, Tim Burton, Ross Hearn, John R Ingram, Alan D. Irvine, Graham A Johnston, Irene Man, Graham S. Ogg, Mandy Wan, Richard B. Warren, Richard Woolf, Nick J. Reynolds, Andrea Manca, Michael R Ardern-Jones, Carsten Flohr, the A-STAR Register Study Group, Mahmud Ali, Michael R Ardern-Jones, Jerome Baldago, Tracy Bale, Paula Beattie, Sara Brown, Victoria Tzortziou Brown, Michael J. Cork, Ser-Ling Chua, S. Darné, Caoimhe Fahy, Leila Ferguson, Carsten Flohr, R M Ross Hearn, Nicola Housam, John R Ingram, Graham A Johnston, E. Ladoyanni, Alison Layton, Claire Leitch, Rosalind Simpson, Irene Man, Deborah Moffit, Louise Newell, Joanne Searle, Sophia Paget, Gabriela Petrof, Urvi Popli, Catherine Rennie, Nick J. Reynolds, Nasim Rouhani, Ann Sergeant, B. D. Thompson, Shyamal Wahie, Richard B. Warren, Aaron Wernham, Richard Woolf, The UK-Irish Atopic eczema Systemic TherApy Register (A-STAR): baseline characteristics of the cohort, British Journal of Dermatology, 192, (5), 2025, p927 - 930, p927-930
Helen Alexander, Saerrah Murryam, Sanja Keži", Ehsan Motazedi, David Prieto"Merino, Alan D. Irvine, Carsten Flohr, Methotrexate and ciclosporin improve skin biomarkers in paediatric atopic dermatitis: results from the TREatment of severe Atopic eczema Trial, British Journal of Dermatology, 193, (2), 2025, p331 - 333, p331-333
Sheng"Pei Wang, Elisha Myers, B.W.M. Arents, Carsten Flohr, Alan D. Irvine, Sinéad Langan, Neil Pearce, Hywel C Williams, Katrina Abuabara, Caution regarding interpretation of trends for the global burden of atopic dermatitis and asthma: a critically appraised topic, British Journal of Dermatology, 194, (2), 2025, p213 - 215, p213-215
Jonathan I. Silverberg, Thomas Bieber, Amy S. Paller, Lisa A. Beck, Masahiro Kamata, L. Puig, Marni Wiseman, Khaled Ezzedine, Alan D. Irvine, Peter Foley, J.Q. Del Rosso, Linda Stein Gold, Erin Johansson, M. Dossenbach, Gaia Gallo, Bülent Akmaz, Marta Casillas, Andrei Karlsson, Tristan Curteis, Raj Chovatiya, Lebrikizumab vs Other Systemic Monotherapies for Moderate-to-Severe Atopic Dermatitis: Network Meta-analysis of Efficacy, Dermatology and Therapy, 15, (3), 2025, p615 - 633, p615-633
Anton Olsson, Kathryn J. A. Steel, Rachael Cooper, Ashley P Jones, Kaitlyn R Chan, Graham S. Ogg, Alan D. Irvine, Carsten Flohr, Leonie S. Taams, Methotrexate and ciclosporin both reduce levels of circulating interleukin (IL)-4 and IL-13 expressing CD4+ memory T cells in childhood atopic dermatitis, Clinical and Experimental Dermatology, 50, (11), 2025, p2249 - 2254, p2249-2254
Jacob P. Thyssen, Caroline Ewertsen, Iben Frier Ruge, Maria Rasmussen Rinnov, Mie Sylow Liljendahl, Maria Zurek Munk"Madsen, Anne"Sofie Halling, Trine Gerner, Nina Haarup Ravn, Mette Hjorslev Knudgaard, Simon Trautner, Lone Skov, Christoph Schlapbach, Simon Francis Thomsen, Alexander Egeberg, Ivone Jakaša, Sanja Keži", Alan D. Irvine, Large Thymus Size at 2 Months Is Associated With Increased Risk of Atopic Dermatitis at Age 2, Allergy, 80, (9), 2025, p2600 - 2609, p2600-2609
Jonathan I. Silverberg, Lawrence F. Eichenfield, Andrew Blauvelt, Alan D. Irvine, Emma Guttman"Yassky, Richard G. Langley, Richard B. Warren, Lars E. French, Jakob Felding, Anne Weiss, Claus B Pedersen, Morten Lind Jensen, Anna Carlsson, Morten Otto Alexander Sommer, Kim Kjøller, Eric L. Simpson, Orismilast, a phosphodiesterase 4B/D inhibitor, in moderate-to-severe atopic dermatitis: efficacy and safety from a multicentre randomized placebo-controlled phase IIb dose-ranging study (ADESOS), British Journal of Dermatology, 192, (6), 2025, p995 - 1006, p995-1006
Alan D. Irvine, Amy S. Paller, Elaine C. Siegfried, Michael J. Cork, Lisa A. Beck, Zhen Chen, C. Peralta, Annie Zhang, Stephane Levy, Sonya Cyr, 105: Growth Analysis at Baseline in Children and Adolescents with Moderate-to-Severe Atopic Dermatitis Enrolled in Phase 3 Dupilumab Trials, Journal of Investigative Dermatology, 145, (3), 2025, pe26 - e26, pe26-e26
Paller, A.S., Mendes-Bastos, P., Siegfried, E., Eichenfield, L.F., Soong, W., Prajapati, V.H., Lio, P., Simpson, E.L., Raymundo, E.M., Suravaram, S., Hu, X., Yang, Y., Huang, X., Calimlim, B.M., Platt, A.M., Su, J.C., Zheng, M., Yamamoto-Hanada, K., Teixeira, H.D., Irvine, A.D., Upadacitinib in Adolescents with Moderate to Severe Atopic Dermatitis: Analysis of 3 Phase 3 Randomized Clinical Trials Through 76 Weeks, JAMA Dermatology, 160, (12), 2024, p1304-1313
Jonathan I. Silverberg, Lawrence F. Eichenfield, Andrew Blauvelt, Alan D. Irvine, Richard G. Langley, Emma Guttman, Richard B. Warren, Lars E. French, Claus Bang Pedersen, Anna Carlsson, Morten Lind Jensen, Morten Otto Alexander Sommer, Kim Kjøller, Eric L. Simpson, 693 - Efficacy and safety of orismilast, a potent PDE4B/D inhibitor, in adults with moderate-to-severe atopic dermatitis: a phase 2b randomized, double-blind, placebo-controlled clinical trial (ADESOS), British Journal of Dermatology, 191, (Supplement_2), 2024
Moussa, A., Bennett, M., Wall, D., Meah, N., York, K., Bokhari, L., Asfour, L., Rees, H., Abraham, L.S., Asz-Sigall, D., Basmanav, F.B., Bergfeld, W., Betz, R.C., Bhoyrul, B., Blume-Peytavi, U., Callender, V., Chitreddy, V., Combalia, A., Cotsarelis, G., Craiglow, B., Dhurat, R., Donovan, J., Doroshkevich, A., Eisman, S., Farrant, P., Ferrando, J., Gadzhigoroeva, A., Green, J., Grimalt, R., Harries, M., Hordinsky, M., Irvine, A., Jolliffe, V., Kaiumov, S., King, B., Lee, J., Lee, W.-S., Li, J., Lortkipanidze, N., McMichael, A., Mesinkovska, N.A., Messenger, A., Mirmirani, P., Olsen, E., Orlow, S.J., Ovcharenko, Y., Piraccini, B.M., Pirmez, R., Rakowska, A., Reygagne, P., Rudnicka, L., Corralo, D.S., Senna, M., Shapiro, J., Sharma, P., Siliuk, T., Starace, M., Suchonwanit, P., Takwale, A., Tosti, A., Vañó-Galván, S., Visser, W.I., Vogt, A., Wade, M., Yip, L., Zhou, C., Sinclair, R., The Alopecia Areata Severity and Morbidity Index (ASAMI) Study: Results from a Global Expert Consensus Exercise on Determinants of Alopecia Areata Severity, JAMA Dermatology, 160, (3), 2024, p341-350
Elizaveta Gribaleva, Carlos Chivardy Moreno, Rayka Malek, David Prieto"Merino, Bolaji Coker, Lilia de la Cruz, Manisha Baden, Paula Beattie, Sara Brown, Tim Burton, Shona Cameron, Michael J. Cork, Ross Hearn, John R Ingram, Alan D. Irvine, G.A. Johnston, Alice Lambert, Irene Man, Louise Newell, Graham S. Ogg, Prakash A. Patel, Mandy Wan, Richard B. Warren, Richard Woolf, Nick J. Reynolds, Andrea Manca, Michael R. Ardern"Jones, Carsten Flohr, P086 The UK-Irish Atopic Eczema Systemic TherApy Register (A-STAR): baseline characteristics of the cohort, British Journal of Dermatology, 191, (Supplement_1), 2024, pi55 - i56, pi55-i56
Lorna Holcroft, Maeve Mc Aleer, Alan D. Irvine, A Novel Likely Pathogenic Variant in NOTCH1 Associated With Primary Lymphedema, Journal of Vascular Anomalies, 5, (1), 2024, pe082 - e082, pe082-e082
Irene Man, Louise Newell, Graham S. Ogg, Prakash A. Patel, Mandy Wan, Richard B. Warren, Richard Woolf, Zenas Z N Yiu, Nick J. Reynolds, Michael R. Ardern"Jones, Carsten Flohr, Helen Alexander, Rayka Malek, David Prieto"Merino, Elizaveta Gribaleva, Manisha Baden, Paula Beattie, Sara Brown, Tim Burton, Shona Cameron, Bola Coker, Michael J. Cork, Ross Hearn, John R Ingram, Alan D. Irvine, G.A. Johnston, Alice Lambert, Mark Lunt, O03 Comparing the treatment effectiveness and safety of ciclosporin, dupilumab and methotrexate in adult and paediatric patients with atopic eczema: results from the UK-Irish A-STAR register, British Journal of Dermatology, 191, (Supplement_1), 2024, pi2 - i3, pi2-i3
Amy S. Paller, Bob Geng, Alan D. Irvine, Elaine C. Siegfried, Michael J. Cork, Michele Ramien, Lawrence F. Eichenfield, Rajan Gupta, Bryan Adams, Marius Ardeleanu, Annie Zhang, 51363 Growth Analysis in Children Aged Less Than 12 Years with Moderate-to-Severe Atopic Dermatitis, Journal of the American Academy of Dermatology, 91, (3), 2024, pAB1 - AB1, pAB1-AB1
Christopher G. Bunick, Raj Chovatiya, Emma Guttman, Mona Shahriari, Mark Boguniewicz, Xinghua Gao, Justin Greiwe, Andrew Blauvelt, Marie L. A. Schuttelaar, Alan D. Irvine, Gweneth F Levy, Andrew M. Platt, Deanne Dilley, Henrique D. Teixeira, Katherine Altman, Ayman Grada, Jonathan I. Silverberg, 533 - Long-term 5-year safety of upadacitinib in moderate-to-severe atopic dermatitis: an integrated analysis including over 7000 patient-years of exposure, British Journal of Dermatology, 190, (Supplement_2), 2024, pii35 - ii36, pii35-ii36
Stamatas, G.N., Sato, T., Chaoimh, C.N., Oddos, T., Insel, R., Hourihane, J.O., Irvine, A.D., Early skin inflammatory biomarker is predictive of development and persistence of atopic dermatitis in infants, Journal of Allergy and Clinical Immunology, 153, (6), 2024, p1597-1603.e4
Traidl-Hoffmann, C., Afghani, J., Akdis, C.A., Akdis, M., Aydin, H., Bärenfaller, K., Behrendt, H., Bieber, T., Bigliardi, P., Bigliardi-Qi, M., Bonefeld, C.M., Bösch, S., Brüggen, M.C., Diemert, S., Duchna, H.-W., Fähndrich, M., Fehr, D., Fellmann, M., Frei, R., Garvey, L.H., Gharbo, R., Gökkaya, M., Grando, K., Guillet, C., Guler, E., Gutermuth, J., Herrmann, N., Hijnen, D.J., Hülpüsch, C., Irvine, A.D., Jensen-Jarolim, E., Kong, H.H., Koren, H., Lang, C.C.V., Lauener, R., Maintz, L., Mantel, P.-Y., Maverakis, E., Möhrenschlager, M., Müller, S., Nadeau, K., Neumann, A.U., O'Mahony, L., Rabenja, F.R., Renz, H., Rhyner, C., Rietschel, E., Ring, J., Roduit, C., Sasaki, M., Schenk, M., Schröder, J., Simon, D., Simon, H.-U., Sokolowska, M., Ständer, S., Steinhoff, M., Piccirillo, D.S., Taïeb, A., Takaoka, R., Tapparo, M., Teixeira, H., Thyssen, J.P., Traidl, S., Uhlmann, M., van de Veen, W., van Hage, M., Virchow, C., Wollenberg, A., Yasutaka, M., Zink, A., Schmid-Grendelmeier, P., Navigating the evolving landscape of atopic dermatitis: Challenges and future opportunities: The 4th Davos declaration, Allergy European Journal of Allergy and Clinical Immunology, 79, (10), 2024, p2605-2624
Katie Ridge, Barry Moran, P. Abigail Alvarado"Vazquez, Jenny Hallgren, Mark A. Little, Alan D. Irvine, Cliona O'Farrelly, Jean Dunne, Conor M. Finlay, Niall Conlon, Lin"CD117+CD34+Fc"RI+ progenitor cells are increased in chronic spontaneous urticaria and predict clinical responsiveness to anti"IgE therapy, Allergy, 79, (9), 2024, p2423-2434
Hebert, A.A., Flohr, C., Hong, H.C.-H., Irvine, A.D., Pierce, E., Elmaraghy, H., Pillai, S., Dawson, Z., Chen, S., Armengol, C., Siegfried, E., Weidinger, S., Efficacy of lebrikizumab in adolescent patients with moderate-to-severe atopic dermatitis: 16-week results from three randomized phase 3 clinical trials, Journal of Dermatological Treatment, 35, (1), 2024
Jonathan I. Silverberg, Alan D. Irvine, Peter Foley, J.Q. Del Rosso, Alexander Schacht, M. Dossenbach, Marta Casillas, Erin Johansson, Gaia Gallo, Linda Stein Gold, 629 - A novel efficacy index for long-term therapy outcomes expressed by maintenance of EASI 75 and IGA 0,1 response in atopic dermatitis, British Journal of Dermatology, 191, (Supplement_2), 2024
Mysler, E., Burmester, G.R., Saffore, C.D., Liu, J., Wegrzyn, L., Yang, C., Betts, K.A., Wang, Y., Irvine, A.D., Panaccione, R., Safety of Upadacitinib in Immune-Mediated Inflammatory Diseases: Systematic Literature Review of Indirect and Direct Treatment Comparisons of Randomized Controlled Trials, Advances in Therapy, 2024
Elaine C. Siegfried, Lawrence F. Eichenfield, Weily Soong, Vimal H. Prajapati, Peter Lio, Eric L. Simpson, Eliza M. Raymundo, Smitha Suravaram, Xiaofei Hu, Yang Yang, Xiaohong Huang, Brian Calimlim, Andrew M. Platt, John Su, Min Zheng, Kiwako Yamamoto"Hanada, Henrique D. Teixeira, Alan D. Irvine, Amy S. Paller, Pedro Mendes"Bastos, Upadacitinib in Adolescents With Moderate to Severe Atopic Dermatitis, JAMA Dermatology, 160, (12), 2024, p1304 - 1304, p1304-1304
Vimal H. Prajapati, Christopher G. Bunick, Kilian Eyerich, Linda Stein Gold, Fabrizio Galimberti, Brian Calimlim, Henrique D. Teixeira, Xiaofei Hu, Yang Yang, Cristina Sancho, Ayman Grada, Alan D. Irvine, 696 - Sustained improvements over 140 weeks in signs, symptoms, and quality of life with upadacitinib in adolescents and adults with moderate-to-severe atopic dermatitis: integrated results from the phase 3 Measure Up 1 and Measure Up 2 studies, British Journal of Dermatology, 191, (Supplement_2), 2024
Brandling-Bennett, H.A., Arkin, L.M., Chiu, Y.E., Hebert, A.A., Callen, J.P., Castelo-Soccio, L., Co, D.O., Cordoro, K.M., Curran, M.L., Dalrymple, A.M., Flohr, C., Gordon, K.B., Hanna, D., Irvine, A.D., Kim, S., Kirkorian, A.Y., Lara-Corrales, I., Lindstrom, J., Paller, A.S., Reyes, M., Begolka, W.S., Tom, W.L., Van Voorhees, A.S., Vleugels, R.A., Lee, L.W., Davies, O., Siegfried, E.C., Executive summary: Consensus treatment guidelines for the use of methotrexate for inflammatory skin disease in pediatric patients, Journal of the American Academy of Dermatology, 90, (6), 2024, p1271-1275
Blauvelt, A., Eyerich, K., Irvine, A.D., de Bruin-Weller, M., Kwatra, S.G., Gooderham, M., Kim, B., Calimlim, B.M., Lee, W.-J., Raymundo, E.M., Liu, Y., Ofori, S., Platt, A.M., Silverberg, J.I., More Time Spent with Clear Skin and No Itch with Upadacitinib versus Dupilumab for Atopic Dermatitis, Dermatology and Therapy, 14, (9), 2024, p2621-2630
Haag, C., Alexis, A., Aoki, V., Bissonnette, R., Blauvelt, A., Chovatiya, R., Cork, M.J., Danby, S.G., Eichenfield, L.F., Eyerich, K., Gooderham, M., Guttman-Yassky, E., Hijnen, D.-J., Irvine, A.D., Katoh, N., Murrell, D.F., Leshem, Y.A., Levin, A.A., Vittrup, I., Olydam, J.I., Orfali, R.L., Paller, A.S., Renert-Yuval, Y., Rosmarin, D., Silverberg, J.I., Thyssen, J.P., Ständer, S., Stefanovic, N., Todd, G., Yu, J., Simpson, E.L., A practical guide to using oral Janus kinase inhibitors for atopic dermatitis from the International Eczema Council, British Journal of Dermatology, 192, (1), 2024, p135-143
Helen Alexander, Saerrah Murryam, Sanja Keži", Ehsan Motazedi, David Prieto"Merino, Alan D. Irvine, Carsten Flohr, Methotrexate and Cyclosporin Improve Skin Biomarkers in Paediatric Atopic Dermatitis: Results from the TREAT Trial, 2024
Kristen Lo Sicco, Jennifer Soung, Bruce Strober, Alan D. Irvine, Dalia Wajsbrot, Kimberly Gromek, Robert Wo"k, David Barnes, Liza Takiya, 52875 Integrated cardiovascular safety analysis of ritlecitinib in patients with alopecia areata (AA) in the phase 2 and phase 3 ALLEGRO clinical trials, and contextualization with a US cohort of patients with AA, Journal of the American Academy of Dermatology, 91, (3), 2024, pAB55 - AB55, pAB55-AB55
Beck, L.A., Weidinger, S., Tauber, M., Saeki, H., Irvine, A.D., Eichenfield, L.F., Werfel, T., Arlert, P., Kurbasic, A., Røpke, M.A., Paller, A., Neutralizing interleukin-13 with tralokinumab reduces abundance of S. aureus in adolescents with atopic dermatitis, Skin Journal of Cutaneous Medicine, 8, (1), 2024, ps324
Ignasi Pau"Charles, Candrice Heath, Andrew Alexis, Michael R. Ardern"Jones, Raj Chovatiya, Carsten Flohr, Alan D. Irvine, Muna Abdula Almurrawi, Amber Reck Atwater, Yuxin Ding, Meihua Qiao, Evangeline Pierce, 517 - Lebrikizumab demonstrates significant efficacy versus placebo across racial and ethnic subgroups in patients with moderate-to-severe atopic dermatitis, British Journal of Dermatology, 190, (Supplement_2), 2024, pii20 - ii21, pii20-ii21
Alan D. Irvine, Amy S. Paller, Sara Hamon, Julie Horowitz, Annamaria Farrell, Sarah Hatsell, Peter Ehmann, Ainara Rodríguez Marco, Ashish Bansal, Zhen Chen, Stephane Levy, Sonya Cyr, 676 - Dupilumab increases levels of bone growth biomarker irrespective of prior use of systemic corticosteroids in children with moderate-to-severe atopic dermatitis, British Journal of Dermatology, 191, (Supplement_2), 2024
Quigley, C., Loftus, C., Clowry, J., Irvine, A.D., Living with a rare disease: a patient perspective of life with trimethylaminuria, Clinical and Experimental Dermatology, 49, (5), 2024, p530-531
Linda Stein Gold, Diamant Thaçi, Norito Katoh, Vivian Shi, Alan D. Irvine, Maria Lucia Buziqui Piruzeli, Sonia Montmayeur, Gaia Gallo, Marjolein de Bruin"Weller, 52041 Safety of lebrikizumab in adults and adolescents with moderate-to-severe atopic dermatitis: integrated analysis from 10 clinical trials, Journal of the American Academy of Dermatology, 91, (3), 2024, pAB307 - AB307, pAB307-AB307
Guttman-Yassky, E., Esfandiari, E., Mano, H., Arai, T., Irvine, A.D., Cork, M.J., Kabashima, K., Chong, C., Simpson, E., Durable improvements in atopic dermatitis in the head and neck and across other anatomic regions with rocatinlimab, Archives of Dermatological Research, 316, (10), 2024
Lee, J., Mannan, A.A., Miyano, T., Irvine, A.D., Tanaka, R.J., In Silico Elucidation of Key Drivers of Staphyloccocus aureus"Staphyloccocus epidermidis"Induced Skin Damage in Atopic Dermatitis Lesions, Jid Innovations, 4, (3), 2024
Anouk G. M. Caron, Astrid M. van Huizen, Annelie H. Musters, Louise A. A. Gerbens, M. A. Middelkamp Hup, Carsten Flohr, Alan D. Irvine, Christian Vestergaard, Ketty Peris, Heather A. Brandling"Bennett, Aaron M. Drucker, Phyllis I. Spuls, the MTX Consensus for AD Survey Study Group, International consensus on methotrexate dosing for patients with atopic dermatitis: An eDelphi study, Journal of the European Academy of Dermatology and Venereology, 39, (2), 2024, p331 - 339, p331-339
Rebecca Carroll, Elizaveta Gribaleva, Rayka Malek, David Prieto"Merino, Manisha Baden, Paula Beattie, Sara Brown, Tim Burton, Shona Cameron, Bola Coker, Michael J. Cork, Ross Hearn, John R Ingram, Alan D. Irvine, G.A. Johnston, Alice Lambert, Irene Man, Louise Newell, Graham S. Ogg, Prakash A. Patel, Mandy Wan, Richard B. Warren, Richard Woolf, Nick J. Reynolds, Michael R. Ardern"Jones, Carsten Flohr, P097 `Real-world" Janus kinase inhibitor treatments in the UK-Irish A-STAR register: cohort profile and treatment outcomes, British Journal of Dermatology, 191, (Supplement_1), 2024, pi61 - i62, pi61-i62
Katie Ridge, Barry Moran, Mark A. Little, Cliona O"Farrelly, Jean Dunne, Julianne Clowry, Clodagh Loftus, Conor M. Finlay, Alan D. Irvine, Niall Conlon, Lin-CD117+CD34+FceRI+ progenitor cells are elevated in atopic dermatitis, 2024
Larney, C., Watson, R., Murray, D., Irvine, A.D., A patient"s experience of progressive hemifacial atrophy, Clinical and Experimental Dermatology, 49, (12), 2024, p1729-1730
Bruce, G., Rosala-Hallas, A., Jones, A.P., Turner, C., Dalton, N., Hilger, E., Baron, S., Beattie, P., Browne, F., Brown, S.J., Gach, J.E., Hearn, R., Esdaile, B., Cork, M.J., Howard, E., Greenblatt, D., August, S., Lovgren, M.-L., Ashoor, F., McPherson, T., O"Kane, D., Ravenscroft, J., Shaw, L., Spowart, C., Thomas, B.R., Sach, T., Wan, M., Irvine, A.D., Sinha, M.D., Flohr, C., The effects of ciclosporin and methotrexate on kidney function in the treatment of severe atopic dermatitis in children: results from the TREAT trial, British Journal of Dermatology, 191, (5), 2024, p851-852
Claudia Traidl"Hoffmann, Jamie Afghani, Cezmi A. Akdi", Mübeccel Akdi", Aydin Handan, Katja Baerenfaller, Heidrun Behrendt, Thomas Bieber, Paul Bigliardi, Mei Bigliardi"Qi, Charlotte M. Bonefeld, Stefanie Bösch, Marie"Charlotte Brüggen, Sebastian Diemert, Hans"Werner Duchna, Martina Fähndrich, Danielle Fehr, Marc Fellmann, Remo Frei, Lene H. Garvey, Raschid Gharbo, Mehmet Gökkaya, Karin Grando, Carole Guillet, Erman Güler, Jan Gutermuth, Nadine Herrmann, DirkJan Hijnen, Claudia Hülpüsch, Alan D. Irvine, Erika Jensen"Jarolim, Heidi H. Kong, Hillel S. Koren, Claudia Lang, Roger Lauener, Laura Maintz, Pierre"Yves Mantel, Emanual Maverakis, M. Moehrenschlager, Svenja Müller, Kari C. Nadeau, Avidan U. Neumann, Liam O"Mahony, Fahafahantsoa Rapelanoro Rabenja, Harald Renz, Claudio Rhyner, Ernst Rietschel, Johannes Ring, Caroline Roduit, Mari Sasaki, Mirjam Schenk, Jens"Michael Schröder, Dagmar Simon, Hans"Uwe Simon, Milena Soko"owska, Sonja Ständer, Martin Steinhoff, Doris Straub Piccirillo, Alain Ta""eb, Roberto Takaoka, Martin Tapparo, Henrique D. Teixeira, Jacob P. Thyssen, Stephan Traidl, Miriam Uhlmann, Willem van de Veen, Marianne van Hage, Christian Virchow, Andreas Wollenberg, Yasutaka Mitamura, Alexander Zink, Peter Schmid"Grendelmeier, Navigating the Evolving Landscape of Atopic Dermatitis: Challenges and Future Opportunities: the 4 th Davos Declaration, 2024
Fagan, N., Browne, F., Dvorakova, V., Carroll, A., Irvine, A.D., Getting it right the first time: an Irish paediatric dermatology perspective from a national care centre, Clinical and Experimental Dermatology, 49, (1), 2024, p61-64
Khatib, C.M., Klein-Petersen, A.W., Rønnstad, A.T.M., Egeberg, A., Christensen, M.O., Silverberg, J.I., Thomsen, S.F., Irvine, A.D., Thyssen, J.P., Increased loss-of-function filaggrin gene mutation prevalence in atopic dermatitis patients across northern latitudes indicates genetic fitness: A systematic review and meta-analysis, Experimental Dermatology, 33, (7), 2024
Casper M. Khatib, Amalie Wandel Klein"Petersen, Amalie Thorsti Møller Rønnstad, Alexander Egeberg, Maria Oberländer Christensen, Jonathan I. Silverberg, Simon Francis Thomsen, Alan D. Irvine, Jacob P. Thyssen, Increased loss"of"function filaggrin gene mutation prevalence in atopic dermatitis patients across northern latitudes indicates genetic fitness: A systematic review and meta"analysis, Experimental Dermatology, 33, (7), 2024, pe15130 - e15130, pe15130-e15130
Lara Wine Lee, Alan D. Irvine, Michele Ramien, Danielle Marcoux, Eulàlia Baselga, Marlies de Graaf, Martti Antila, Nelson Augusto Rosário Filho, Irene Lara"Corrales, Joel C. Joyce, Rajan Gupta, Patrick Redman, Annie Zhang, 692 - Dupilumab reduces atopic dermatitis lesion severity and extent in children <12 years of age with moderate-to-severe AD: interim results from the PEDISTAD real-world registry, British Journal of Dermatology, 191, (Supplement_2), 2024
Alexander, H., Malek, R., Prieto-Merino, D., Gribaleva, E., Baden, M., Beattie, P., Brown, S., Burton, T., Cameron, S., Coker, B., Cork, M.J., Hearn, R., Ingram, J.R., Irvine, A.D., Johnston, G.A., Lambert, A., Lunt, M., Man, I., Newell, L., Ogg, G., Patel, P., Wan, M., Warren, R.B., Woolf, R., Yiu, Z.Z.N., Reynolds, N., Ardern-Jones, M.R., Flohr, C., A prospective observational cohort study comparing the treatment effectiveness and safety of ciclosporin, dupilumab and methotrexate in adult and paediatric patients with atopic dermatitis: results from the UK"Irish A-STAR register, British Journal of Dermatology, 191, (6), 2024, p988-999
Wang, S.-P., Stefanovic, N., Orfali, R.L., Aoki, V., Brown, S.J., Dhar, S., Eichenfield, L.F., Flohr, C., Ha, A., Mora, C., Murase, J.E., Rosenbach, M., Srinivas, S.M., Thyssen, J.P., Wei, M.L., Irvine, A.D., Abuabara, K., Impact of climate change on atopic dermatitis: A review by the International Eczema Council, Allergy European Journal of Allergy and Clinical Immunology, 79, (6), 2024, p1455-1469
Eulàlia Baselga, Michele Ramien, Danielle Marcoux, Marlies de Graaf, Alan D. Irvine, Vânia Oliveira Carvalho, Ledit Ardusso, Mirna Toledo"Bahena, Rajan Gupta, Thu Tong, Annie Zhang, 509 - Dupilumab improves disease severity in children less than 12 years of age with moderate-severe AD: interim results from PEDISTAD real-world registry, British Journal of Dermatology, 190, (Supplement_2), 2024, pii13 - ii14, pii13-ii14
Ridge, K., Moran, B., Alvarado-Vazquez, P.A., Hallgren, J., Little, M.A., Irvine, A.D., O'Farrelly, C., Dunne, J., Finlay, C.M., Conlon, N., Lin"CD117+CD34+Fc"RI+ progenitor cells are increased in chronic spontaneous urticaria and predict clinical responsiveness to anti-IgE therapy, Allergy: European Journal of Allergy and Clinical Immunology, 2024
Renert-Yuval, Y., Del Duca, E., Arents, B., Bissonnette, R., Drucker, A.M., Flohr, C., Guttman-Yassky, E., Hijnen, D., Kabashima, K., Leshem, Y.A., Paller, A.S., Silverberg, J.I., Simpson, E.L., Spuls, P., Vestergaard, C., Wollenberg, A., Irvine, A.D., Thyssen, J.P., Treat-to-target in dermatology: A scoping review and International Eczema Council survey on the approach in atopic dermatitis, Journal of the European Academy of Dermatology and Venereology, 38, (1), 2024, p42-51
Clowry Juliann, Dempsey Daniel J, Claxton Tracey J, Towell Aisling M, Turley Mary B, Sutton Marti, Geoghegan Joan A, Kezic Sanj, Jakasa Ivon, White Arthu, Irvine Alan D, McLoughlin Rachel M, Distinct T cell signatures are associated with Staphylococcus aureus skin infection in pediatric atopic dermatitis, 9, (9), 2024, p1-19
Tierney, E., Evans, P., Broderick, V., Wynn, R., Irvine, A.D., Successful response to dupilumab in a refractory case of atopic dermatitis-like chronic cutaneous graft-versus-host disease, British Journal of Dermatology, 190, (4), 2024, p581-583
Paller, A.S., Scharschmidt, T.C., Kezic, S., Irvine, A.D., Preclinical Atopic Dermatitis Skin in Infants: An Emerging Research Area, Journal of Investigative Dermatology, 144, (5), 2024, p1001-1009
ASAMI Consensus Survey Study Group, Anthony Moussa, Michaela Bennett, Dmitri Wall, Nekma Meah, Katherine York, Laita Bokhari, Leila Asfour, Huw Rees, Leonardo Spagnol Abraham, Daniel Asz"Sigall, F. Buket Basmanav, Wilma F. Bergfeld, Regina C. Betz, Bevin Bhoyrul, Ulrike Blume"Peytavi, Valerie Callender, Vijaya Chitreddy, Andrea Combalía, George Cotsarelis, Brittany G. Craiglow, Rachita Dhurat, Jeff Donovan, Andrei G. Doroshkevich, Samantha Eisman, Paul Farrant, Juan Ferrando, Aida Gadzhigoroeva, Jack Green, Ramón Grimalt, Matthew Harries, Maria Hordinsky, Alan D. Irvine, Victoria Jolliffe, Spartak Kaiumov, Brett King, Joyce Lee, Won"Soo Lee, Jane Li, Nino Lortkipanidze, Amy McMichael, Natasha Atanaskova Mesinkovska, Andrew G. Messenger, Paradi Mirmirani, Elise A. Olsen, Seth J. Orlow, Yuliya Ovcharenko, Bianca Maria Piraccini, Rodrigo Pirmez, Adriana Rakowska, Pascal Reygagne, Lidia Rudnicka, David Saceda Corralo, Maryanne M. Senna, Jerry Shapiro, Pooja Sharma, Tatiana Siliuk, Michela Starace, Poonkiat Suchonwanit, Anita Takwale, Antonellá Tosti, Sérgio Vañó-Galván, Willem I. Visser, Annika Vogt, Martin Wade, Leona Yip, Cheng Zhou, Rodney Sinclair, The Alopecia Areata Severity and Morbidity Index (ASAMI) Study, JAMA Dermatology, 160, (3), 2024, p341 - 341, p341-341
Sara Brown, Carsten Flohr, Parwez Hossain, Alan D. Irvine, G.A. Johnston, Mark A. Lane, Sinéad Langan, Philip Laws, Daniel O"Driscoll, Donal O"Kane, Alice Payne, Gabriela Petrof, Andrew Pink, Saaeha Rauz, Scott Robbie, Sri Gore, Mili Shah, Richard Woolf, Chenxi Wang, Stoyana Tumbeva, M.F. Mohd Mustapa, Michael R. Ardern"Jones, An expert consensus on managing dupilumab-related ocular surface disorders in people with atopic dermatitis 2024, British Journal of Dermatology, 191, (6), 2024, p865 - 885, p865-885
Carter Haag, Andrew Alexis, Valéria Aoki, Robert Bissonnette, Andrew Blauvelt, Raj Chovatiya, Michael J. Cork, Simon G. Danby, Lawrence F. Eichenfield, Kilian Eyerich, Melinda Gooderham, Emma Guttman"Yassky, DirkJan Hijnen, Alan D. Irvine, Norito Katoh, Dédée F. Murrell, Yael A. Leshem, Adriane A. Levin, Ida Vittrup, Jill I. Olydam, Raquel Leão Orfali, Amy S. Paller, Yael Renert"Yuval, David Rosmarin, Jonathan I. Silverberg, Jacob P. Thyssen, Sonja Ständer, Nick Stefanovic, Gail Todd, JiaDe Yu, Eric L. Simpson, A practical guide to using oral Janus kinase inhibitors for atopic dermatitis from the International Eczema Council, British Journal of Dermatology, 192, (1), 2024, p135 - 143, p135-143
Alan D. Irvine, Jonathan O'. B. Hourihane, Reply to correspondence "Food allergens to emollients", Allergy, 78, (4), 2023, p1123-1123
Lawrence F. Eichenfield, Carsten Flohr, Christine Bangert, Alan D. Irvine, Stephan Weidinger, John Nesnas, Herwig Koppensteiner, Fan Zhang, Ricardo Rojo, Gary Chan, 426 Efficacy and safety of abrocitinib in adolescents with moderate-to-severe atopic dermatitis from the JADE clinical trial program, British Journal of Dermatology, 188, (Supplement_3), 2023
Musters, A.H., Broderick, C., Prieto-Merino, D., Chiricozzi, A., Damiani, G., Peris, K., Dhar, S., De, A., Freeman, E., Arents, B.W.M., Burton, T., Bosma, A.L.-A.L., Chi, C.-C., Fletcher, G., Drucker, A.M., Kabashima, K., de Monchy, E.F., Panda, M., Wall, D.R., Vestergaard, C., Mahé, E., Bonzano, L., Kattach, L., Napolitano, M., Ordoñez-Rubiano, M.F., Haufe, E., Patruno, C., Irvine, A.D., Spuls, P.I., Flohr, C., The effects of systemic immunomodulatory treatments on COVID-19 outcomes in patients with atopic dermatitis: Results from the global SECURE-AD registry, Journal of the European Academy of Dermatology and Venereology, 37, (2), 2023, p365-381
Siegfried, E.C., Arkin, L.M., Chiu, Y.E., Hebert, A.A., Callen, J.P., Castelo-Soccio, L., Co, D.O., Cordoro, K.M., Curran, M.L., Dalrymple, A.M., Flohr, C., Gordon, K.B., Hanna, D., Irvine, A.D., Kim, S., Kirkorian, A.Y., Lara-Corrales, I., Lindstrom, J., Paller, A.S., Reyes, M., Begolka, W.S., Tom, W.L., Van Voorhees, A.S., Vleugels, R.A., Lee, L.W., Davies, O.M.T., Brandling-Bennett, H.A., Methotrexate for inflammatory skin disease in pediatric patients: Consensus treatment guidelines, Pediatric Dermatology, 40, (5), 2023, p789-808
Amy S. Paller, Lawrence F. Eichenfield, Jonathan I. Silverberg, Michael J. Cork, Christine Bangert, Alan D. Irvine, Stephan Weidinger, S. Barbarot, Haiyun Fan, Justine Alderfer, Herwig Koppensteiner, Kanti Chittuluru, 383 Integrated safety analysis of abrocitinib in 635 adolescent patients with moderate-to-severe atopic dermatitis with over 1000 patient-years of exposure, British Journal of Dermatology, 188, (Supplement_3), 2023
Guttman-Yassky, E., Irvine, A.D., Brunner, P.M., Kim, B.S., Boguniewicz, M., Parmentier, J., Platt, A.M., Kabashima, K., The role of Janus kinase signaling in the pathology of atopic dermatitis, Journal of Allergy and Clinical Immunology, 152, (6), 2023, p1394-1404
Alan D. Irvine, Thishi Surendranathan, Liz Hennessy, Ivana Rajkovic, Annette Durkan, Dearbhla Coughlan, Sean Conlon, Richard Hudson, A real"world retrospective observational study exploring resource use for secondary care management of moderate"to"severe atopic dermatitis in children and adolescents at a single site in Ireland, JEADV Clinical Practice, 2, (3), 2023, p465-478
Alan D. Irvine, Amy S. Paller, Sara Hamon, Julie Horowitz, Annamaria Farrell, Sarah Hatsell, Ainara Rodríguez Marco, Ashish Bansal, Zhen Chen, Sonya Cyr, 340 Dupilumab treatment of children with moderate-to-severe atopic dermatitis increases bone alkaline phosphatase, a marker of bone mineralization, British Journal of Dermatology, 188, (Supplement_2), 2023
Peter Lio, Lawrence F. Eichenfield, Danielle Marcoux, Wan"Ju Lee, Henrique D. Teixeira, Eliza M. Raymundo, Amy E. Gamelli, Ayman Grada, Xiaofei Hu, Alan D. Irvine, 42065 Improvement in Itch, Symptoms, and Quality of Life With Upadacitinib Through Week 16 in Adults and Adolescents With Atopic Dermatitis: Results From Phase 3 Studies (Measure Up 1, Measure Up 2, and AD Up), Journal of the American Academy of Dermatology, 89, (3), 2023, pAB178 - AB178, pAB178-AB178
Guttman-Yassky, E., Thyssen, J.P., Silverberg, J.I., Papp, K.A., Paller, A.S., Weidinger, S., Chih-ho Hong, H., Hendrickson, B., Dilley, D., Tenorio, A.R., Ladizinski, B., Chu, A.D., Liu, J., Irvine, A.D., Safety of upadacitinib in moderate-to-severe atopic dermatitis: An integrated analysis of phase 3 studies, Journal of Allergy and Clinical Immunology, 151, (1), 2023, p172-181
Amy S. Paller, Barry Ladizinski, Pedro Mendes"Bastos, Elaine C. Siegfried, Weily Soong, Vimal H. Prajapati, Peter Lio, Jacob P. Thyssen, Eric L. Simpson, Andrew M. Platt, Eliza M. Raymundo, Jianzhong Liu, Brian Calimlim, Xiaohong Huang, Yihua Gu, Xiaofei Hu, Yang Yang, John Su, Min Zheng, Kiwako Yamamoto"Hanada, Henrique D. Teixeira, Alan D. Irvine, Efficacy and Safety of Upadacitinib Treatment in Adolescents With Moderate-to-Severe Atopic Dermatitis, JAMA Dermatology, 159, (5), 2023, p526 - 526, p526-526
Flohr, C., Rosala-Hallas, A., Jones, A.P., Beattie, P., Baron, S., Browne, F., Brown, S.J., Gach, J.E., Greenblatt, D., Hearn, R., Hilger, E., Esdaile, B., Cork, M.J., Howard, E., Lovgren, M.-L., August, S., Ashoor, F., Williamson, P.R., McPherson, T., O"Kane, D., Ravenscroft, J., Shaw, L., Sinha, M.D., Spowart, C., Taams, L.S., Thomas, B.R., Wan, M., Sach, T.H., Irvine, A.D., Efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children and young people (TREAT): A multicentre parallel group assessor-blinded clinical trial, British Journal of Dermatology, 189, (6), 2023, p674-684
Cathal O'Connor, Vicki Livingstone, Jonathan O"B Hourihane, Alan D. Irvine, Geraldine Boylan, Deirdre Murray, Early emollient bathing is associated with subsequent atopic dermatitis in an unselected birth cohort study, Pediatric Allergy and Immunology, 34, (7), 2023
Canaud, G., Lopez Gutierrez, J.C., Irvine, A.D., Vabres, P., Hansford, J.R., Ankrah, N., Branle, F., Papadimitriou, A., Ridolfi, A., O'Connell, P., Turner, S., Adams, D.M., Alpelisib for treatment of patients with PIK3CA-related overgrowth spectrum (PROS), Genetics in Medicine, 25, (12), 2023
Ismail, M., Doelger, E., Eckert, D., Irvine, A.D., Chu, A.D., Teixeira, H.D., Liu, W., Nader, A., Population pharmacokinetic and exposure-response modelling to inform upadacitinib dose selection in adolescent and adult patients with atopic dermatitis, British Journal of Clinical Pharmacology, 89, (10), 2023, p3139-3151
Burmester, G.R., Cohen, S.B., Winthrop, K.L., Nash, P., Irvine, A.D., Deodhar, A., Mysler, E., Tanaka, Y., Liu, J., Lacerda, A.P., Palac, H., Shaw, T., Mease, P.J., Guttman Yassky, E., Safety profile of upadacitinib over 15 000 patient-years across rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and atopic dermatitis, RMD Open, 9, (1), 2023
Amy S. Paller, Jonathan I. Silverberg, Michael J. Cork, Emma Guttman"Yassky, Benjamin Lockshin, Alan D. Irvine, Moon Bum Kim, Kenji Kabashima, Zhen Chen, Yufang Lü, Ashish Bansal, Ana B. Rossi, Arsalan Shabbir, Efficacy and Safety of Dupilumab in Patients With Erythrodermic Atopic Dermatitis, JAMA Dermatology, 159, (3), 2023, p255 - 255, p255-255
Silverberg, J.I., Guttman-Yassky, E., Thaçi, D., Irvine, A.D., Stein Gold, L., Blauvelt, A., Simpson, E.L., Chu, C.-Y., Liu, Z., Gontijo Lima, R., Pillai, S.G., Seneschal, J., Two Phase 3 Trials of Lebrikizumab for Moderate-to-Severe Atopic Dermatitis, New England Journal of Medicine, 388, (12), 2023, p1080-1091
Nicholas Stefanovic, Alan D. Irvine, Filaggrin and beyond, Annals of Allergy Asthma & Immunology, 132, (2), 2023, p187 - 195, p187-195
Paller, A.S., Flohr, C., Eichenfield, L.F., Irvine, A.D., Weisman, J., Soung, J., Pinto Correia, A., Natalie, C.R., Rodriguez Capriles, C., Pierce, E., Reifeis, S., Gontijo Lima, R., Armengol Tubau, C., Laquer, V., Weidinger, S., Safety and Efficacy of Lebrikizumab in Adolescent Patients with Moderate-to-Severe Atopic Dermatitis: A 52-Week, Open-Label, Phase 3 Study, Dermatology and Therapy, 13, (7), 2023, p1517-1534
Peter Lio, Lawrence F. Eichenfield, Danielle Marcoux, Wan"Ju Lee, Henrique D. Teixeira, Eliza M. Raymundo, Amy Gamelli, Ayman Grada, Xiaofei Hu, Alan D. Irvine, 413 Improvement in itch, symptoms and quality of life with upadacitinib through week 16 in adults and adolescents with atopic dermatitis: results from phase 3 studies (Measure Up 1, Measure Up 2 and AD Up), British Journal of Dermatology, 188, (Supplement_3), 2023
Takahiro Sato, Richard A. Insel, Alan D. Irvine, Georgios N. Stamatas, Jonathan O"B Hourihane, Early Skin Inflammatory Biomarker is Predictive of Development and Persistence of Atopic Dermatitis in Infants up to 12m of age, Journal of Allergy and Clinical Immunology, 151, (2), 2023, pAB326 - AB326, pAB326-AB326
Paller, A.S., Ladizinski, B., Mendes-Bastos, P., Siegfried, E., Soong, W., Prajapati, V.H., Lio, P., Thyssen, J.P., Simpson, E.L., Platt, A.M., Raymundo, E.M., Liu, J., Calimlim, B.M., Huang, X., Gu, Y., Hu, X., Yang, Y., Su, J.C., Zheng, M., Yamamoto-Hanada, K., Teixeira, H.D., Irvine, A.D., Efficacy and Safety of Upadacitinib Treatment in Adolescents with Moderate-to-Severe Atopic Dermatitis: Analysis of the Measure Up 1, Measure Up 2, and AD Up Randomized Clinical Trials, JAMA Dermatology, 159, (5), 2023, p526-535
Emma Guttman"Yassky, Stephan Weidinger, Jonathan I. Silverberg, Melinda Gooderham, Jacob P. Thyssen, Alan D. Irvine, Hany Elmaraghy, Chitra R Natalie, Chen Hu, Evangeline Pierce, E.G. Gil, Eric L. Simpson, 94 Maintenance of efficacy and safety with lebrikizumab up to one year of treatment in patients with moderate-to-severe atopic dermatitis with or without topical corticosteroids, Journal of Investigative Dermatology, 143, (11), 2023, pS348 - S348, pS348-S348
April W. Armstrong, Jonathan I. Silverberg, Jacob P. Thyssen, Richard B. Warren, Alan D. Irvine, Eric Wolf, Yuxin Ding, Yong Lin, Sarah A. Reifeis, M. Falqués, Eric L. Simpson, 395 Assessing imputation methods with the lebrikizumab clinical trial program, British Journal of Dermatology, 188, (Supplement_3), 2023
Paller, A.S., Silverberg, J.I., Cork, M.J., Guttman-Yassky, E., Lockshin, B., Irvine, A.D., Kim, M.B., Kabashima, K., Chen, Z., Lu, Y., Bansal, A., Rossi, A.B., Shabbir, A., Efficacy and Safety of Dupilumab in Patients with Erythrodermic Atopic Dermatitis: A Post Hoc Analysis of 6 Randomized Clinical Trials, JAMA Dermatology, 159, (3), 2023, p255-266
Carsten Flohr, Alan D Irvine, Michael J Cork, Eric L Simpson, Andreas Wollenberg, Mette Deleuran, Amy Praestgaard, Ryan B Thomas, Ana B Rossi, Dupilumab improves patient-reported symptoms and health-related quality of life in children aged 6"11 years with severe atopic dermatitis, British Journal of Dermatology, 189, (2), 2023, p238-240
Duggan, C., Irvine, A.D., O"B Hourihane, J., Kiely, M.E., Murray, D.M., ASQ-3 and BSID-III"s concurrent validity and predictive ability of cognitive outcome at 5 years, Pediatric Research, 94, (4), 2023, p1465-1471
Fiona Lynch, Veronika Dvo"áková, Alan D. Irvine, Detection of NRAS Mutation in Kaposiform Lymphangiomatosis Using Cell-free DNA from Plasma, Journal of Vascular Anomalies, 4, (1), 2023, pe062 - e062, pe062-e062
Bosma, A.L., Ouwerkerk, W., Heidema, M.J., Prieto-Merino, D., Ardern-Jones, M.R., Beattie, P., Brown, S.J., Ingram, J.R., Irvine, A.D., Ogg, G., Patel, P., Reynolds, N.J., Hearn, R.M.R., Wan, M., Warren, R.B., Woolf, R.T., Hyseni, A.M., Gerbens, L.A.A., Spuls, P.I., Flohr, C., Middelkamp-Hup, M.A., Comparison of real-world treatment outcomes of systemic immunomodulating therapy in atopic dermatitis patients with dark and light skin types, JAAD International, 10, 2023, p14-24
J. Zdybski, Andreas Wollenberg, Carsten Flohr, Patrick M. Brunner, Wolfgang Högler, Alexander Egeberg, Alan D. Irvine, Heng Fan, Pinaki Biswas, Smaail Radi, Saleem A. Farooqui, Herwig Koppensteiner, Sarah P. Sherlock, Gary Chan, 201 Bone safety data in adolescents with moderate-to-severe atopic dermatitis treated with abrocitinib: interim results from the JADE EXTEND MRI substudy, Journal of Investigative Dermatology, 143, (11), 2023, pS366 - S366, pS366-S366
Nousbeck, Janna, McAleer, Maeve A., Irvine, Alan D., Peripheral Blood Gene Expression Profile of Infants with Atopic Dermatitis, JID Innovations, 3, (2), 2023, p100165
Carol Ní Chaoimh, Dhanis Lad, Claudio Nico, Gerwin J. Puppels, X. F. Colin C. Wong, John E. Common, Deirdre M. Murray, Alan D. Irvine, Jonathan O"Brien Hourihane, Early initiation of short"term emollient use for the prevention of atopic dermatitis in high"risk infants"The STOP"AD randomised controlled trial, Allergy, 78, (4), 2023, p984-994
Lisa A. Beck, Stephan Weidinger, Campus Kiel, Hidehisa Saeki, Alan D. Irvine, Lawrence F. Eichenfield, Thomas Werfel, Petra Arlert, Azra Kurbasic, Mads A. Røpke, Amy S. Paller, 43966 Targeting interleukin-13 with tralokinumab reduces S. aureus abundance in adolescents with atopic dermatitis, Journal of the American Academy of Dermatology, 89, (3), 2023, pAB92 - AB92, pAB92-AB92
Beck, L.A., Bieber, T., Weidinger, S., Tauber, M., Saeki, H., Irvine, A.D., Eichenfield, L.F., Werfel, T., Arlert, P., Jiang, L., Røpke, M., Paller, A.S., Tralokinumab treatment improves the skin microbiota by increasing the microbial diversity in adults with moderate-to-severe atopic dermatitis: Analysis of microbial diversity in ECZTRA 1, a randomized controlled trial, Journal of the American Academy of Dermatology, 88, (4), 2023, p816-823
Bieber, T., Feist, E., Irvine, A.D., Harigai, M., Haladyj, E., Ball, S., Deberdt, W., Issa, M., Grond, S., Taylor, P.C., Correction to: A Review of Safety Outcomes from Clinical Trials of Baricitinib in Rheumatology, Dermatology and COVID-19 (Advances in Therapy, (2022), 39, 11, (4910-4960), 10.1007/s12325-022-02281-4), Advances in Therapy, 40, (9), 2023, p4114-4115
Thomas Bieber, Jacob P Thyssen, Alan D Irvine, Yuichiro Tsunemi, Yun-Fei Chen, Luna Sun, Andrea Schloebe, Elisabeth Riedl, Michael J Cork, Early improvements in signs and symptoms predict clinical response to baricitinib in patients with moderate-to-severe atopic dermatitis, Clinical and Experimental Dermatology, 48, (8), 2023, p881-888
Paller, A.S., Ladizinski, B., Mendes-Bastos, P., Siegfried, E., Soong, W., Prajapati, V.H., Lio, P., Thyssen, J.P., Simpson, E.L., Platt, A.M., Raymundo, E.M., Liu, J., Calimlim, B.M., Huang, X., Gu, Y., Hu, X., Yang, Y., Su, J.C., Zheng, M., Yamamoto-Hanada, K., Teixeira, H.D., Irvine, A.D., Efficacy and Safety of Upadacitinib Treatment in Adolescents with Moderate-to-Severe Atopic Dermatitis: Analysis of the Measure Up 1, Measure Up 2, and AD Up Randomized Clinical Trials, JAMA Dermatology, 159, (5), 2023, p526-535
Walsh, Carleen, Leavey, Gerard, Mc Laughlin, Marian, Paller, Amy S, Irvine, Alan D, Browne, Fiona, Mellerio, Jemima E, Bewley, Anthony, Novel mixed-method, inclusive protocol involving global key stakeholders, including carers as experts, to co-develop relevant Caregiver-Reported Outcome Domains (CRODs) in skin disease, BMJ Open, 13, (1), 2023, pe068893
Nicole Fagan, Fiona Browne, Veronika Dvorakova, Áine Carroll, Alan D Irvine, `Guidelines are not the issue, access to support and advice is the problem": a cross-sectional survey of general practitioners referring to paediatric dermatology, Clinical and Experimental Dermatology, 49, (1), 2023, p71-72
Augustin, M., Nosbaum, A., Werfel, T., Grond, S., Reed, C., Lampropoulou, A., Tietz, N., Irvine, A.D., Riedl, E., Treatment satisfaction of adult patients with moderate-to-severe atopic dermatitis treated with baricitinib in France, Germany, and the United Kingdom: results from a cross-sectional international patient survey, Journal of Dermatological Treatment, 34, (1), 2023
Eyerich, K., Gooderham, M.J., Silvestre, J.F., Shumack, S.P., Mendes-Bastos, P., Aoki, V., Ortoncelli, M., Silverberg, J.I., Teixeira, H.D., Chen, S.H., Calimlim, B.M., Takemoto, S., Sancho, C., Fritz, B., Irvine, A.D., Real-world clinical, psychosocial and economic burden of atopic dermatitis: Results from a multicountry study, Journal of the European Academy of Dermatology and Venereology, 2023
Jonathan I. Silverberg, Christopher G. Bunick, Peter Lio, Emma Guttman"Yassky, Mark Boguniewicz, Andrew Blauvelt, Thomas Bieber, Jacob P. Thyssen, Smitha Suravaram, Nasser Khan, Deanne Dilley, Henrique D. Teixeira, Namita Vigna, Amy Gamelli, Ayman Grada, Alan D. Irvine, 427 Long-term 4-year safety of upadacitinib in moderate-to-severe atopic dermatitis: results of an integrated analysis of phase 3 studies, British Journal of Dermatology, 188, (Supplement_3), 2023
Zuberbier, T., Abdul Latiff, A., Aggelidis, X., Augustin, M., Balan, R.-G., Bangert, C., Beck, L., Bieber, T., Bernstein, J.A., Bertolin Colilla, M., Berardi, A., Bedbrook, A., Bindslev-Jensen, C., Bousquet, J., de Bruin-Weller, M., Bruscky, D., Buyuktiryaki, B., Canonica, G.W., Castro, C., Chanturidze, N., Chong-Neto, H.J., Chu, C.-Y., Chularojanamontri, L., Cork, M., Criado, R.F.J., Barredo, L.C., Custovic, A., Darsow, U., Emurlai, A., de Pablo, A., Del Giacco, S., Girolomoni, G., Deleva Jovanova, T., Deleuran, M., Douladiris, N., Duarte, B., Dubakiene, R., Eller, E., Engel-Yeger, B., Ensina, L.F., Filho, N.R., Flohr, C., Fomina, D., Francuzik, W., Galimberti, M.L., Giménez-Arnau, A.M., Godse, K., Mortz, C.G., Gotua, M., Hide, M., Hoetzenecker, W., Hunzelmann, N., Irvine, A., Jack, C., Kanavarou, I., Katoh, N., Kinaciyan, T., Kocatürk, E., Kulthanan, K., Lapeere, H., Lau, S., Machado Forti Nastri, M., Makris, M., Mansour, E., Marsland, A., Morelo Rocha Felix, M., Moschione Castro, A.P., Nettis, E., Nicolas, J.F., Nosbaum, A., Odemyr, M., Papapostolou, N., Parisi, C.A.S., Paudel, S., Peter, J., Pokharel, P., Puig, L., Quint, T., Ramon, G.D., Regateiro, F., Ricci, G., Rosario, C., Sackesen, C., Schmid-Grendelmeier, P., Serra-Baldrich, E., Siemens, K., Smith, C., Staubach, P., Stevanovic, K., Su-Kücük, Ö., Sussman, G., Tavecchio, S., Teovska Mitrevska, N., Thaci, D., Toubi, E., Traidl-Hoffmann, C., Treudler, R., Vadasz, Z., van Hofman, I., Ventura, M.T., Wang, Z., Werfel, T., Wollenberg, A., Yang, A., Weng Yew, Y., Zhao, Z., Zwiener, R., Worm, M., A concept for integrated care pathways for atopic dermatitis"A GA2LEN ADCARE initiative, Clinical and Translational Allergy, 13, (9), 2023
Mussa, Alessandro, Leoni, Chiara, Iacoviello, Matteo, Carli, Diana, Ranieri, Carlotta, Pantaleo, Antonino, Buonuomo, Paola Sabrina, Bagnulo, Rosanna, Ferrero, Giovanni Battista, Bartuli, Andrea, Melis, Daniela, Maitz, Silvia, Loconte, Daria Carmela, Turchiano, Antonella, Piglionica, Marilidia, De Luisi, Annunziata, Susca, Francesco Claudio, Bukvic, Nenad, Forleo, Cinzia, Selicorni, Angelo, Zampino, Giuseppe, Onesimo, Roberta, Cappuccio, Gerarda, Garavelli, Livia, Novelli, Chiara, Memo, Luigi, Morando, Carla, Della Monica, Matteo, Accadia, Maria, Capurso, Martina, Piscopo, Carmelo, Cereda, Anna, Di Giacomo, Marilena Carmela, Saletti, Veronica, Spinelli, Alessandro Mauro, Lastella, Patrizia, Tenconi, Romano, Dvorakova, Veronika, Irvine, Alan D., Resta, Nicoletta, Genotypes and phenotypes heterogeneity in PIK3CA-related overgrowth spectrum and overlapping conditions: 150 novel patients and systematic review of 1007 patients with PIK3CA pathogenetic variants, Journal of Medical Genetics, 60, (2), 2023, p163-173
Budu-Aggrey, A., Kilanowski, A., Sobczyk, M.K., Shringarpure, S.S., Mitchell, R., Reis, K., Reigo, A., Mägi, R., Nelis, M., Tanaka, N., Brumpton, B.M., Thomas, L.F., Sole-Navais, P., Flatley, C., Espuela-Ortiz, A., Herrera-Luis, E., Lominchar, J.V.T., Bork-Jensen, J., Marenholz, I., Arnau-Soler, A., Jeong, A., Fawcett, K.A., Baurecht, H., Rodriguez, E., Alves, A.C., Kumar, A., Sleiman, P.M., Chang, X., Medina-Gomez, C., Hu, C., Xu, C.-J., Qi, C., El-Heis, S., Titcombe, P., Antoun, E., Fadista, J., Wang, C.A., Thiering, E., Xiao, S., Kress, S., Kothalawala, D.M., Kadalayil, L., Duan, J., Zhang, H., Hoffmann, T., Jorgenson, E., Choquet, H., Risch, N., Njølstad, P., Andreassen, O.A., Johansson, S., Almqvist, C., Gong, T., Ullemar, V., Karlsson, R., Magnusson, P.K.E., Szwajda, A., Burchard, E.G., Thyssen, J.P., Hansen, T., Kårhus, L.L., Dantoft, T.M., Jeanrenaud, A.C.S.N., Ghauri, A., Arnold, A., Homuth, G., Lau, S., Nöthen, M.M., Hübner, N., Imboden, M., Visconti, A., Falchi, M., Bataille, V., Hysi, P., Ballardini, N., Boomsma, D.I., Hottenga, J.J., Müller-Nurasyid, M., Ahluwalia, T.S., Stokholm, J., Chawes, B., Schoos, A.-M., Esplugues, A., Bustamante, M., Raby, B., Arshad, H., German, C., Esko, T., Milani, L.A., Metspalu, A., Terao, C., Abuabara, K., Løset, M., Hveem, K., Jacobsson, B., Pino-Yanes, M., Strachan, D.P., Grarup, N., Linneberg, A., Lee, Y.-A., Probst-Hensch, N., Weidinger, S., Jarvelin, M.-R., Melén, E., Hakonarson, H., Irvine, A.D., Jarvis, D.L., Nijsten, T., Duijts, L., Vonk, J.M., Koppelmann, G.H., Godfrey, K.M., Barton, S.J., Feenstra, B., Pennell, C.E., Sly, P.D., Holt, P.G., Williams, K.L., Bisgaard, H., Bønnelykke, K., Curtin, J., Simpson, A., Murray, C., Schikowski, T., Bunyavanich, S., Weiss, S.T., Holloway, J.W., Min, J., Brown, S.J., Standl, M., Paternoster, L., European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation, medRxiv, 2022
Werfel, T., Irvine, A.D., Bangert, C., Seneschal, J., Grond, S., Cardillo, T., Brinker, D., Zhong, J., Riedl, E., Wollenberg, A., An integrated analysis of herpes virus infections from eight randomized clinical studies of baricitinib in adults with moderate-to-severe atopic dermatitis, Journal of the European Academy of Dermatology and Venereology, 36, (9), 2022, p1486-1496
Nicholas Stefanovic, Conor J. Fitzmaurice, Patrick Ormond, Alan D. Irvine, Rupert B. Barry, Risk factors for distant metastasis in cutaneous squamous cell carcinoma, British Journal of Dermatology, 187, (3), 2022, p435-436
Guillaume Canaud, Alan D. Irvine, Denise M. Adams, Nii Ankrah, P.R. O'Connell, J.C. López Gutiérrez, 468P Clinical benefit of alpelisib in pediatric patients with PIK3CA-related overgrowth spectrum (PROS): An EPIK-P1 analysis, Annals of Oncology, 33, 2022, pS755 - S755, pS755-S755
Cox F, Bigley V, Irvine A, Leahy R, Conlon N., PAMI Syndrome: Two Cases of an Autoinflammatory Disease with an ALPS-Like Phenotype., Journal of clinical immunology, 42, (5), 2022, p955-958
Ghaffarpour, N., Baselga, E., Boon, L.M., Diociaiuti, A., Dompmartin, A., Dvorakova, V., El Hachem, M., Gasparella, P., Haxhija, E., Kyrklund, K., Irvine, A.D., Kapp, F.G., Rößler, J., Salminen, P., van den Bosch, C., van der Vleuten, C., Kool, L.S., Vikkula, M., The VASCERN-VASCA working group diagnostic and management pathways for lymphatic malformations, European Journal of Medical Genetics, 65, (12), 2022
Budu-Aggrey, A., Kilanowski, A., Sobczyk, M.K., Shringarpure, S.S., Mitchell, R., Reis, K., Reigo, A., Mägi, R., Nelis, M., Tanaka, N., Brumpton, B.M., Thomas, L.F., Sole-Navais, P., Flatley, C., Espuela-Ortiz, A., Herrera-Luis, E., Lominchar, J.V.T., Bork-Jensen, J., Marenholz, I., Arnau-Soler, A., Jeong, A., Fawcett, K.A., Baurecht, H., Rodriguez, E., Alves, A.C., Kumar, A., Sleiman, P.M., Chang, X., Medina-Gomez, C., Hu, C., Xu, C.-J., Qi, C., El-Heis, S., Titcombe, P., Antoun, E., Fadista, J., Wang, C.A., Thiering, E., Xiao, S., Kress, S., Kothalawala, D.M., Kadalayil, L., Duan, J., Zhang, H., Hoffmann, T., Jorgenson, E., Choquet, H., Risch, N., Njølstad, P., Andreassen, O.A., Johansson, S., Almqvist, C., Gong, T., Ullemar, V., Karlsson, R., Magnusson, P.K.E., Szwajda, A., Burchard, E.G., Thyssen, J.P., Hansen, T., Kårhus, L.L., Dantoft, T.M., Jeanrenaud, A.C.S.N., Ghauri, A., Arnold, A., Homuth, G., Lau, S., Nöthen, M.M., Hübner, N., Imboden, M., Visconti, A., Falchi, M., Bataille, V., Hysi, P., Ballardini, N., Boomsma, D.I., Hottenga, J.J., Müller-Nurasyid, M., Ahluwalia, T.S., Stokholm, J., Chawes, B., Schoos, A.-M., Esplugues, A., Bustamante, M., Raby, B., Arshad, H., German, C., Esko, T., Milani, L.A., Metspalu, A., Terao, C., Abuabara, K., Løset, M., Hveem, K., Jacobsson, B., Pino-Yanes, M., Strachan, D.P., Grarup, N., Linneberg, A., Lee, Y.-A., Probst-Hensch, N., Weidinger, S., Jarvelin, M.-R., Melén, E., Hakonarson, H., Irvine, A.D., Jarvis, D.L., Nijsten, T., Duijts, L., Vonk, J.M., Koppelmann, G.H., Godfrey, K.M., Barton, S.J., Feenstra, B., Pennell, C.E., Sly, P.D., Holt, P.G., Williams, K.L., Bisgaard, H., Bønnelykke, K., Curtin, J., Simpson, A., Murray, C., Schikowski, T., Bunyavanich, S., Weiss, S.T., Holloway, J.W., Min, J., Brown, S.J., Standl, M., Paternoster, L., European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation, medRxiv, 2022
Bieber, T., Feist, E., Irvine, A.D., Harigai, M., Haladyj, E., Ball, S., Deberdt, W., Issa, M., Grond, S., Taylor, P.C., A Review of Safety Outcomes from Clinical Trials of Baricitinib in Rheumatology, Dermatology and COVID-19, Advances in Therapy, 39, (11), 2022, p4910-4960
Cathal O'Connor, Vicki Livingstone, Jonathan O'. B. Hourihane, Alan D. Irvine, Geraldine Boylan, Deirdre Murray, Parental atopy and risk of atopic dermatitis in the first two years of life in the BASELINE birth cohort study, Pediatric Dermatology, 2022
Kezic, S., McAleer, M.A., Jakasa, I., Goorden, S.M.I., der Vlugt, K.G.-V., Beers-Stet, F.S., Meijer, J., Roelofsen, J., Nieman, M.M., van Kuilenburg, A.B.P., Irvine, A.D., Children with atopic dermatitis show increased activity of ß-glucocerebrosidase and stratum corneum levels of glucosylcholesterol that are strongly related to the local cytokine milieu, British Journal of Dermatology, 186, (6), 2022, p988-996
Diociaiuti, A., Baselga, E., Boon, L.M., Dompmartin, A., Dvorakova, V., El Hachem, M., Gasparella, P., Haxhija, E., Ghaffarpour, N., Kyrklund, K., Irvine, A.D., Kapp, F.G., Rößler, J., Salminen, P., van den Bosch, C., van der Vleuten, C., Kool, L.S., Vikkula, M., The VASCERN-VASCA working group diagnostic and management pathways for severe and/or rare infantile hemangiomas, European Journal of Medical Genetics, 65, (6), 2022
Takuya Miyano, Alan D. Irvine, Reiko J. Tanaka, Model-Based Meta-Analysis to Optimize Staphylococcus aureus"Targeted Therapies for Atopic Dermatitis, JID Innovations, 2, (3), 2022, p100110
Paller, A.S., Guttman-Yassky, E., Schuttelaar, M.L.A., Irvine, A.D., Baselga, E., Kataoka, Y., Antila, M., de Bruin-Weller, M.S., Marcoux, D., Abramova, A., Rizova, E., Liu, C., Zhang, A., Disease characteristics, comorbidities, treatment patterns and quality of life impact in children <12 years old with atopic dermatitis: Interim results from the PEDISTAD Real-World Registry, Journal of the American Academy of Dermatology, 87, (5), 2022, p1104-1108
Cathal O"Connor, Alan D. Irvine, Deirdre Murray, Michelle Murphy, Jonathan O"B Hourihane, Geraldine Boylan, Study protocol: assessing SleeP IN infants with early-onset atopic Dermatitis by Longitudinal Evaluation (The SPINDLE study), BMC Pediatrics, 22, (1), 2022
Guttman-Yassky, Emma, Teixeira, Henrique D, Simpson, Eric L, Papp, Kim A, Pangan, Aileen L, Blauvelt, Andrew, Thaçi, Diamant, Chu, Chia-Yu, Hong, H Chih-ho, Katoh, Norito, Paller, Amy S, Calimlim, Brian, Gu, Yihua, Hu, Xiaofei, Liu, Meng, Yang, Yang, Liu, John, Tenorio, Allan R, Chu, Alvina D, Irvine, Alan D, Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double-blind, randomised controlled phase 3 trials, The Lancet, 397, (10290), 2021, p2151-2168
Alan D. Irvine, Mette Deleuran, Amy Praestgaard, Dimittri Delevry, Randy Prescilla, Ana B. Rossi, 27431 Dupilumab treatment improves health-related quality of life in children aged "6 to <12 years with severe atopic dermatitis, Journal of the American Academy of Dermatology, 85, (3), 2021, pAB144 - AB144, pAB144-AB144
Doherty AM, Colleran GC, Durcan L, Irvine AD, Barrett E, A pilot study of burnout and long covid in senior specialist doctors., Irish journal of medical science, 2021
Jennifer M. E. Boggs, Alan D. Irvine, PLACK syndrome resulting from a novel homozygous variant in CAST, Pediatric Dermatology, 2021
Wall, Dmitri, Meah, Nekma, York, Katherine, Bhoyrul, Bevin, Bokhari, Laita, Abraham, Leonardo Spagnol, Adams, Roisín, Bergfeld, Wilma, Betz, Regina C., Blume-Peytavi, Ulrike, Callender, Valerie, Campbell, Chel, Chambers, Jen, Chen, Gang, Chitreddy, Vijaya, Cotsarelis, George, Craiglow, Brittany, Dhurat, Rachita, Dlova, Ncoza, Donovan, Jeff, Duque-Estrada, Bruna, Eisman, Samantha, Ellison, Abby, Farrant, Paul, Barberá, Juan Ferrando, Gadzhigoroeva, Aida, Grimalt, Ramon, Harries, Matthew, Hordinsky, Maria, Irvine, Alan D., Jolliffe, Victoria, Jones, Leslie, King, Brett, Lee, Won-Soo, Lortkipanidze, Nino, McMichael, Amy, Messenger, Andrew, Mirmirani, Paradi, Olsen, Elise, Orlow, Seth J., Ovcharenko, Yuliya, Piraccini, Bianca Maria, Pirmez, Rodrigo, Rakowska, Adriana, Reygagne, Pascal, Riley, Melissa, Rudnicka, Lidia, Saceda Corralo, David, Shapiro, Jerry, Sharma, Pooja, Silyuk, Tatiana, Kaiumov, Spartak, Tobin, Desmond J., Tosti, Antonella, Vañó-Galván, Sergio, Vogt, Annika, Wade, Martin, Yip, Leona, Zlotogorski, Abraham, Zhou, Cheng, Sinclair, Rodney, A Global eDelphi Exercise to Identify Core Domains and Domain Items for the Development of a Global Registry of Alopecia Areata Disease Severity and Treatment Safety (GRASS), JAMA Dermatology, 157, (4), 2021, p439
Thomas Werfel, Alan D. Irvine, Christine Bangert, Julien Sénéschal, Susanne Grond, T. Cardillo, Jinglin Zhong, Elisabeth Riedl, Andreas Wollenberg, Dennis Brinker, 084 Herpes virus infections amongst moderate to severe atopic dermatitis patients treated with baricitinib: an integrated analysis of phase 3 trials, Journal of Investigative Dermatology, 141, (10), 2021, pS162 - S162, pS162-S162
Stefanovic, Nicholas, Irvine, Alan D., Flohr, Carsten, The Role of the Environment and Exposome in Atopic Dermatitis, Current Treatment Options in Allergy, 8, (3), 2021, p222-241
McCarthy, Elaine K, Murray, Deirdre M, Hourihane, Jonathan O"B, Kenny, Louise C, Irvine, Alan D, Kiely, Mairead E, Behavioral consequences at 5 y of neonatal iron deficiency in a low-risk maternal"infant cohort, The American Journal of Clinical Nutrition, 113, (4), 2021, p1032-1041
Takuya Miyano, Alan D Irvine, Reiko J Tanaka, Model-based meta-analysis to optimise S. aureus-targeted therapies for atopic dermatitis, 2021
Meah, Nekma, Wall, Dmitri, York, Katherine, Bhoyrul, Bevin, Bokhari, Laita, Asz-Sigall, Daniel, Bergfeld, Wilma F., Betz, Regina C., Blume-Peytavi, Ulrike, Callender, Valerie, Chitreddy, Vijaya, Combalia, Andrea, Cotsarelis, George, Craiglow, Brittany, Donovan, Jeff, Eisman, Samantha, Farrant, Paul, Green, Jack, Grimalt, Ramon, Harries, Matthew, Hordinsky, Maria, Irvine, Alan D., Itami, Satoshi, Jolliffe, Victoria, King, Brett, Lee, Won-Soo, McMichael, Amy, Messenger, Andrew, Mirmirani, Paradi, Olsen, Elise, Orlow, Seth J., Piraccini, Bianca Maria, Rakowska, Adriana, Reygagne, Pascal, Roberts, Janet L., Rudnicka, Lidia, Shapiro, Jerry, Sharma, Pooja, Tosti, Antonella, Vogt, Annika, Wade, Martin, Yip, Leona, Zlotogorski, Abraham, Sinclair, Rodney D., The Alopecia Areata Consensus of Experts (ACE) study part II: Results of an international expert opinion on diagnosis and laboratory evaluation for alopecia areata, Journal of the American Academy of Dermatology, 84, (6), 2021, p1594-1601
Nousbeck, J., McAleer, M. A., Hurault, G., Kenny, E., Harte, K., Kezic, S., Tanaka, R. J., Irvine, A. D., Analysis of small RNA molecules in childhood atopic dermatitis reveals a role for miR-451a, British Journal of Dermatology, 184, (3), 2021
Wall, Dmitri, Alhusayen, Raed, Arents, Bernd, Apfelbacher, Christian, Balogh, Esther A., Bokhari, Laita, Bloem, Manja, Bosma, Angela L., Burton, Tim, Castelo-Soccio, Leslie, Fagan, Nicole, Feldman, Steven R., Fletcher, Godfrey, Flohr, Carsten, Freeman, Esther, French, Lars E., Griffiths, Christopher E.M., Hruza, George J., Ingram, John R., Kappelman, Michael D., Lara-Corrales, Irene, Lim, Henry W., Meah, Nekma, McMahon, Devon E., Mahil, Satveer K., McNicoll, Ian, Musters, Annelie, Naik, Haley B., Sinclair, Rodney, Smith, Catherine H., Spuls, Phyllis, Tobin, Desmond J., York, Katherine, Irvine, Alan D., Learning from disease registries during a pandemic: Moving toward an international federation of patient registries, Clinics in Dermatology, 39, (3), 2021, p467-478
Takuya Miyano, Alan D. Irvine, Reiko Tanaka, 046 A computational model suggested potential therapies for dupilumab poor responders in atopic dermatitis, Journal of Investigative Dermatology, 141, (10), 2021, pS156 - S156, pS156-S156
Xing, Chao, Kanchwala, Mohammed, Rios, Jonathan J., Hyatt, Tommy, Wang, Richard C., Tran, An, Dougherty, Irene, Tovar"Garza, Andrea, Purnadi, Christy, Kumar, Monique G., Berk, David, Shinawi, Marwan, Irvine, Alan D., Toledo"Bahena, Mirna, Agim, Nnenna G., Glass, Donald A., Biallelic variants in RNU12 cause CDAGS syndrome, Human Mutation, 42, (8), 2021, p1042-1052
Hotz, Alrun, Kopp, Julia, Bourrat, Emmanuelle, Oji, Vinzenz, Komlosi, Katalin, Giehl, Kathrin, Bouadjar, Bakar, Bygum, Anette, Tantcheva-Poor, Iliana, Hellström Pigg, Maritta, Has, Cristina, Yang, Zhou, Irvine, Alan D., Betz, Regina C., Zambruno, Giovanna, Tadini, Gianluca, Süßmuth, Kira, Gruber, Robert, Schmuth, Matthias, Mazereeuw-Hautier, Juliette, Jonca, Natalie, Guez, Sophie, Brena, Michela, Hernandez-Martin, Angela, van den Akker, Peter, Bolling, Maria C., Hannula-Jouppi, Katariina, Zimmer, Andreas D., Alter, Svenja, Vahlquist, Anders, Fischer, Judith, Meta-Analysis of Mutations in ALOX12B or ALOXE3 Identified in a Large Cohort of 224 Patients, Genes, 12, (1), 2021, p80
Freeman, Esther E., Chamberlin, Grace C., McMahon, Devon E., Hruza, George J., Wall, Dmitri, Meah, Nekma, Sinclair, Rodney, Balogh, Esther A., Feldman, Steven R., Lowes, Michelle A., Marzano, Angelo V., Naik, Haley B., Castelo-Soccio, Leslie, Lara-Corrales, Irene, Cordoro, Kelly M., Mahil, Satveer K., Griffiths, Christopher E.M., Smith, Catherine H., Irvine, Alan D., Spuls, Phyllis I., Flohr, Carsten, French, Lars E., Dermatology COVID-19 Registries, Dermatologic Clinics, 39, (4), 2021, p575-585
Silverberg, Jonathan I., Simpson, Eric L., Armstrong, April W., de Bruin-Weller, Marjolein S., Irvine, Alan D., Reich, Kristian, Expert Perspectives on Key Parameters that Impact Interpretation of Randomized Clinical Trials in Moderate-to-Severe Atopic Dermatitis, American Journal of Clinical Dermatology, 2021
Takuya Miyano, Alan D Irvine, Reiko J Tanaka, A mathematical model to identify optimal combinations of drug targets for dupilumab poor responders in atopic dermatitis, 2021
Lucy E. Bradshaw, Rachel H. Haines, Kim S. Thomas, Joanne R. Chalmers, Alan D. Irvine, Hywel C. Williams, Sara J. Brown, Clinical examination for hyperlinear palms to determine filaggrin genotype: A diagnostic test accuracy study, Clinical & Experimental Allergy, 2021
Delles, C, Dayan, C M, Dominiczak, A F, Donnelly, S C, Irvine, A D, Announcing the first AoP webinar: `Can evidence-based medicine survive in a pandemic?", QJM: An International Journal of Medicine, 114, (1), 2021, p11-12
Bradshaw, Lucy E., Haines, Rachel H., Thomas, Kim S., Chalmers, Joanne R., Irvine, Alan D., Williams, Hywel C., Brown, Sara J., Clinical examination for hyperlinear palms to determine filaggrin genotype: A diagnostic test accuracy study, Clinical & Experimental Allergy, 51, (11), 2021, p1421-1428
A.R. Mulick, K.E. Mansfield, R.J. Silverwood, A. Budu"Aggrey, A. Roberts, A. Custovic, N. Pearce, A.D. Irvine, L. Smeeth, K. Abuabara, S.M. Langan, Four childhood atopic dermatitis subtypes identified from trajectory and severity of disease and internally validated in a large UK birth cohort, British Journal of Dermatology, 185, (3), 2021, p526--536
Onoufriadis, A., Cabezas, A., Ng, J.C.F., Canales, J., Costas, M.J., Ribeiro, J.M., Rodrigues, J.R., McAleer, M.A., Castelo"Soccio, L., Simpson, M.A., Fraternali, F., Irvine, A.D., Cameselle, J.C., McGrath, J.A., Autosomal recessive hypotrichosis with loose anagen hairs associated with TKFC mutations*, British Journal of Dermatology, 184, (5), 2021, p935-943
Takuya Miyano, Alan D Irvine, Reiko J Tanaka, Model-based meta-analysis to optimise S. aureus-targeted therapies for atopic dermatitis, 2021
Alan D. Irvine, Mette Deleuran, Amy Praestgaard, Dimittri Delevry, Noah A. Levit, Ana B. Rossi, 397 Dupilumab improves health-related quality of life (HRQoL) in children aged "6"<12 years with severe atopic dermatitis (AD), Journal of Investigative Dermatology, 141, (5), 2021, pS69 - S69, pS69-S69
Emma Guttman"Yassky, Alan D. Irvine, Jonathan I. Silverberg, Kim Papp, Amy S. Paller, Brian Waterhouse, Allan R. Tenorio, Barry Ladizinski, Alvina D. Chu, John Liu, Kristian Reich, 27082 Upadacitinib in moderate-to-severe atopic dermatitis: Combined safety analysis of phase 3 studies (Measure Up 1, Measure Up 2, and AD Up), Journal of the American Academy of Dermatology, 85, (3), 2021, pAB129 - AB129, pAB129-AB129
Holm, Annegret, te Loo, Maroeska, Schultze Kool, Leo, Salminen, Päivi, Celis, Veronica, Baselga, Eulalia, Duignan, Sophie, Dvorakova, Veronika, Irvine, Alan D., Boon, Laurence M., Vikkula, Miikka, Ghaffarpour, Nader, Niemeyer, Charlotte M., Rössler, Jochen, Kapp, Friedrich G., Efficacy of Sirolimus in Patients Requiring Tracheostomy for Life-Threatening Lymphatic Malformation of the Head and Neck: A Report From the European Reference Network, Frontiers in Pediatrics, 9, 2021
Deleuran, M, Marcoux, D, Bruin-Weller, M, Irvine, A, Baselga, E, Ahn, K, Castro, A, Bansal, A, Chao, J, Bégo-Le-Bagousse, G, Rossi, A, Dupilumab Provides Significant Clinical Benefit in a Phase 3 Trial in Adolescents with Uncontrolled Atopic Dermatitis Irrespective of Prior Systemic Immunosuppressant Use, Acta Dermato Venereologica, 101, (7), 2021, padv00504
Wall, Dmitri, Alhusayen, Raed, Arents, Bernd, Apfelbacher, Christian, Balogh, Esther A., Bokhari, Laita, Bloem, Manja, Bosma, Angela L., Burton, Tim, Castelo-Soccio, Leslie, Fagan, Nicole, Feldman, Steven R., Fletcher, Godfrey, Flohr, Carsten, Freeman, Esther, French, Lars E., Griffiths, Christopher E. M., Hruza, George J., Ingram, John R., Kappelman, Michael D., Lara-Corrales, Irene, Lim, Henry W., Meah, Nekma, McMahon, Devon E., Mahil, Satveer K., McNicoll, Ian, Musters, Annelie, Naik, Haley B., Sinclair, Rodney, Smith, Catherine H., Spuls, Phyllis, Tobin, Desmond J., York, Katherine, Irvine, Alan D., Edited by Min Deng, MD Learning from disease registries during a pandemic: Moving toward an international federation of patient registries, Clinics in Dermatology, 39, (3), 2021, p467-478
Abuabara, K., Nicholls, S.G., Langan, S.M., Guttman"Yassky, E., Reynolds, N.J., Paller, A.S., Brown, S.J., , , Priority research questions in atopic dermatitis: an International Eczema Council eDelphi consensus, British Journal of Dermatology, 185, (1), 2021, p203-205
Kilian Eyerich, Philip B. Sugerman, Meijing Wu, Björn Fritz, Alan D. Irvine, 27000 The real-world burden of atopic dermatitis"Initial results from a multicountry study, Journal of the American Academy of Dermatology, 85, (3), 2021, pAB125 - AB125, pAB125-AB125
Towell AM, Feuillie C, Vitry P, Da Costa TM, Mathelié-Guinlet M, Kezic S, Fleury OM, McAleer MA, Dufrêne YF, Irvine AD, Geoghegan JA, Staphylococcus aureus binds to the N-terminal region of corneodesmosin to adhere to the stratum corneum in atopic dermatitis, Proceedings of the National Academy of Sciences of the United States of America, 118, (1), 2021, pe2014444118
Freeman, Esther E., Chamberlin, Grace C., McMahon, Devon E., Hruza, George J., Wall, Dmitri, Meah, Nekma, Sinclair, Rodney, Balogh, Esther A., Feldman, Steven R., Lowes, Michelle A., Marzano, Angelo, V, Naik, Haley B., Castelo-Soccio, Leslie, Lara-Corrales, Irene, Cordoro, Kelly M., Mahil, Satveer K., Griffiths, Christopher E. M., Smith, Catherine H., Irvine, Alan D., Spuls, Phyllis, I, Flohr, Carsten, French, Lars E., Dermatology COVID-19 Registries Updates and Future Directions, Dermatologic Clinics, 39, (4), 2021, p575-585
Amy Mulick, Kathryn E. Mansfield, Richard J. Silverwood, Ashley Budu"Aggrey, Amanda J. Roberts, Adnan "ustovi", Neil Pearce, Alan D. Irvine, Liam Smeeth, Katrina Abuabara, Sinéad Langan, 247 Four childhood atopic dermatitis subtypes identified from trajectory and severity of disease, Journal of Investigative Dermatology, 141, (5), 2021, pS44 - S44, pS44-S44
Takuya Miyano, Alan D Irvine, Reiko J Tanaka, A mathematical model to identify optimal combinations of drug targets for dupilumab poor responders in atopic dermatitis, 2021
Mulick, A.R., Mansfield, K.E., Silverwood, R.J., Budu"Aggrey, A., Roberts, A., Custovic, A., Pearce, N., Irvine, A.D., Smeeth, L., Abuabara, K., Langan, S.M., Four childhood atopic dermatitis subtypes identified from trajectory and severity of disease and internally validated in a large UK birth cohort, British Journal of Dermatology, 185, (3), 2021, p526-536
Fagan, Nicole, Meah, Nekma, York, Katherine, Bokhari, Laita, Fletcher, Godfrey, Chen, Gang, Tobin, Desmond J., Messenger, Andrew, Irvine, Alan D., Sinclair, Rodney, Wall, Dmitri, Shedding light on therapeutics in alopecia and their relevance to COVID-19, Clinics in Dermatology, 39, (1), 2021, p76-83
Luger, T., Paller, A.S., Irvine, A.D., Sidbury, R., Eichenfield, L.F., Werfel, T., Bieber, T., Topical therapy of atopic dermatitis with a focus on pimecrolimus, Journal of the European Academy of Dermatology and Venereology, 35, (7), 2021, p1505-1518
Sarah E. Corcoran, Iva Hafner"Bratkovi", Reena Halai, Raquel Domingo-Fernandéz, Daire O"Leary, Kathy Banahan, Roman Jerala, Niall Conlon, Thomas Jung, Luke O'neill, Matthew A. Cooper, Alan D. Irvine, The NLRP3 inhibitor MCC950 inhibits IL-1ß production in PBMC from 19 patients with Cryopyrin-Associated Periodic Syndrome and in 2 patients with Schnitzler"s Syndrome, Wellcome Open Research, 5, 2020, p247 - 247, p247-247
Karina Forde, Nicoletta Resta, Carlotta Ranieri, David Rea, Olga Kubassova, Mark Hinton, Alan D Irvine, Veronika Dvorakova, Clinical Experience with the AKT1 Inhibitor Miransertib in two Children with PIK3CA-related overgrowth syndrome, 2020
Meah, Nekma, Wall, Dmitri, York, Katherine, Bhoyrul, Bevin, Bokhari, Laita, Asz Sigall, Daniel, Bergfeld, Wilma F., Betz, Regina C., Blume-Peytavi, Ulrike, Callender, Valerie, Chitreddy, Vijaya, Combalia, Andrea, Cotsarelis, George, Craiglow, Brittany, Donovan, Jeff, Eisman, Samantha, Farrant, Paul, Green, Jack, Grimalt, Ramon, Harries, Matthew, Hordinsky, Maria, Irvine, Alan D., Itami, Satoshi, Jolliffe, Victoria, King, Brett, Lee, Won-Soo, McMichael, Amy, Messenger, Andrew, Mirmirani, Paradi, Olsen, Elise, Orlow, Seth J., Piraccini, Bianca Maria, Rakowska, Adriana, Reygagne, Pascal, Roberts, Janet L., Rudnicka, Lidia, Shapiro, Jerry, Sharma, Pooja, Tosti, Antonella, Vogt, Annika, Wade, Martin, Yip, Leona, Zlotogorski, Abraham, Sinclair, Rodney, The Alopecia Areata Consensus of Experts (ACE) study: Results of an international expert opinion on treatments for alopecia areata, Journal of the American Academy of Dermatology, 83, (1), 2020, p123-130
Alsaleemi A, O'Connor C, Irvine AD, Leahy TR., Topical cidofovir for the treatment of recalcitrant viral warts and molluscum contagiosum in Jacobsen syndrome., Pediatric dermatology, 37, (6), 2020, p1191-1192
F.M. Vermeulen, L.A.A. Gerbens, J. Schmitt, M. Deleuran, A.D. Irvine, K. Logan, W. Ouwerkerk, C. Vestergaard, C. Flohr, P.I. Spuls, The European TREatment of ATopic eczema (TREAT) Registry Taskforce survey: prescribing practices in Europe for phototherapy and systemic therapy in adult patients with moderate"to"severe atopic eczema*, British Journal of Dermatology, 2020
Elaine K. McCarthy, Deirdre M. Murray, Louise C. Kenny, J.O. Hourihane, Alan D. Irvine, Máiréad Kiely, Long-lasting behavioural consequences of neonatal iron deficiency in high-risk children, Proceedings of The Nutrition Society, 79, (OCE2), 2020
Freeman, Esther E., McMahon, Devon E., Hruza, George J., Irvine, Alan D., Spuls, Phyllis I., Smith, Catherine H., Mahil, Satveer K., Castelo-Soccio, Leslie, Cordoro, Kelly M., Lara-Corrales, Irene, Naik, Haley B., Alhusayen, Raed, Ingram, John R., Feldman, Steven R., Balogh, Esther A., Kappelman, Michael D., Wall, Dmitri, Meah, Nekma, Sinclair, Rodney, Beylot-Barry, Marie, Fitzgerald, Matthew, French, Lars E., Lim, Henry W., Griffiths, Christopher E. M., Flohr, Carsten, International collaboration and rapid harmonization across dermatologic COVID-19 registries, Journal of the American Academy of Dermatology, 83, (3), 2020, pe261-e266
Mahil, S. K., Yiu, Z. Z. N., Mason, K. J., Dand, N., Coker, B., Wall, D., Fletcher, G., Bosma, A., Capon, F., Iversen, L., Langan, S. M., Di Meglio, P., Musters, A. H., Prieto-Merino, D., Tsakok, T., Warren, R. B., Flohr, C., Spuls, P. I., Griffiths, C. E. M., Barker, J., Irvine, A. D., Smith, C. H., Global reporting of cases of COVID-19 in psoriasis and atopic dermatitis: an opportunity to inform care during a pandemic, British Journal of Dermatology, 183, (2), 2020, p404-406
Ní Chaoimh, C., Nico, C., Puppels, G.J., Caspers, P.J., Wong, X.F.C.C., Common, J.E., Irvine, A.D., Hourihane, J.O., In vivo Raman spectroscopy discriminates between FLG loss-of-function carriers vs wild-type in day 1-4 neonates, Annals of Allergy, Asthma and Immunology, 124, (5), 2020, p500-504
H. Blakeway, V. Van"de"Velde, V.B. Allen, G. Kravvas, L. Palla, M.J. Page, C. Flohr, R.B. Weller, A.D. Irvine, T. McPherson, A. Roberts, H.C. Williams, N. Reynolds, S.J. Brown, L. Paternoster, S.M. Langan, What is the evidence for interactions between filaggrin null mutations and environmental exposures in the aetiology of atopic dermatitis? A systematic review, British Journal of Dermatology, 2020
Lenehan, Sonia M., Boylan, Geraldine B., Livingstone, Vicki, Fogarty, Leanna, Twomey, Deirdre Marie, Nikolovski, Janeta, Irvine, Alan D., Kiely, Mairead, Kenny, Louise C., Hourihane, Jonathon O. B., Murray, Deirdre M., The impact of short-term predominate breastfeeding on cognitive outcome at 5 years, Acta Paediatrica, 109, (5), 2020, p982-988
Drislane, C., Irvine, A.D., The role of filaggrin in atopic dermatitis and allergic disease, Annals of Allergy, Asthma and Immunology, 124, (1), 2020, p36-43
J. Nousbeck, M.A. McAleer, G. Hurault, E. Kenny, K. Harte, S. Kezic, R.J. Tanaka, A.D. Irvine, MicroRNA analysis of childhood atopic dermatitis reveals a role for miR"451a, British Journal of Dermatology, 2020
Paller, Amy S., Guttman-Yassky, Emma, Irvine, Alan D., Baselga, Eulalia, de Bruin-Weller, Marjolein, Jayawardena, Shyamalie, Zhang, Annie, Mina-Osorio, Paola, Rizova, Elena, Ozturk, Zafer E., Protocol for a prospective, observational, longitudinal study in paediatric patients with moderate-to-severe atopic dermatitis (PEDISTAD): study objectives, design and methodology, BMJ Open, 10, (3), 2020, pe033507
Marek Haftek, Maeve A McAleer, Ivone Jakasa, WH Irwin McLean, Sanja Kezic, Alan D. Irvine, Changes in nano-mechanical properties of human epidermal cornified cells in children with atopic dermatitis, Wellcome Open Research, 5, 2020, p97
Alexander Hooftman, Stefano Angiari, Svenja Hester, Sarah E Corcoran, Marah C Runisch, Chris Ling, Melanie C Ruzek, Peter F Slivka, Anne F McGettrick, Kathy Banahan, Mark M Hughes, Alan D Irvine, Roman Fischer, Luke A J O'Neill, The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation, Cell Metabolism, 2020
L. Cunningham, V. Dvorakova, F. Browne, A.D. Irvine, High dose Bilastine for the treatment of Bascule Syndrome, Clinical and Experimental Dermatology, 2020
Thyssen J.P., Jakasa I., Riethmuller C., Schon M.P., Braun A., Haftek M., Fallon P.G., Wroblewski J., Jakubowski H., Eckhart L., Declercq W., Koppes S., Engebretsen K.A., Bonefeld C., Irvine A.D., Keita-Alassane S., Simon M., Kawasaki H., Kubo A., Amagai M., Matsui T., Kezic S., Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and Stiffness in Mice, Journal of Investigative Dermatology, 140, (3), 2020, p615 - 623.e5, p615-623.e5
M.A. McAleer, I. Jakasa, N. Stefanovic, W.H.I. McLean, S. Kezic, A.D. Irvine, Topical Corticosteroids Normalize both Skin and Systemic Inflammatory Markers in Infant Atopic Dermatitis, British Journal of Dermatology, 2020
Sinéad Langan, Alan D. Irvine, Stephan Weidinger, Atopic dermatitis, The Lancet, 396, (10247), 2020, p345 - 360, p345-360
Doreen Siegels, Annice Heratizadeh, Susanne Abraham, Jonas Binnmyr, Knut Brockow, Alan D. Irvine, Susanne Halken, Charlotte G Mortz, Carsten Flohr, Peter Schmid"Grendelmeier, Lauri"Ann Poel, Antonella Muraro, Stephan Weidinger, Thomas Werfel, Jochen Schmitt, Systemic treatments in the management of atopic dermatitis: A systematic review and meta"analysis, Allergy, 2020
Eyerich, K., Brown, S.J., Perez White, B.E., Tanaka, R.J., Bissonette, R., Dhar, S., Bieber, T., Hijnen, D.J., Guttman-Yassky, E., Irvine, A., Thyssen, J.P., Vestergaard, C., Werfel, T., Wollenberg, A., Paller, A.S., Reynolds, N.J., Human and computational models of atopic dermatitis: A review and perspectives by an expert panel of the International Eczema Council, Journal of Allergy and Clinical Immunology, 143, (1), 2019, p36-45
Revencu, N., Fastre, E., Ravoet, M., Helaers, R., Brouillard, P., Bisdorff-Bresson, A., Chung, C.W.T., Gerard, M., Dvorakova, V., Irvine, A.D., Boon, L.M., Vikkula, M., RASA1 mosaic mutations in patients with capillary malformation-arteriovenous malformation, Journal of Medical Genetics, 2019
A.D. Irvine, P. Mina"Osorio, Disease trajectories in childhood atopic dermatitis: an update and practitioner's guide, British Journal of Dermatology, 2019
Petra Staubach, Jonathan I. Silverberg, Marjolein de Bruin"Weller, Alan D. Irvine, Marius Ardeleanu, Z. Chen, Claire Clibborn, A. Sorrentino, Ana B. Rossi, 178 Effect of Dupilumab on Global Individual Signs Score Outcomes in Adults With Moderate-to-Severe Atopic Dermatitis: Combined Results From Four Phase 3 Trials, Journal of Investigative Dermatology, 139, (9), 2019, pS244 - S244, pS244-S244
Schwartz C, Moran T, Saunders S.P, Kaszlikowska A, Floudas A, Bom J, Nunez G, Iwakura Y, Oâ Neill L, Irvine A.D, McKenzie A.N.J, Ogg G, Walsh P.T, Demengeot J, Fallon P.G, Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL-1β, Allergy: European Journal of Allergy and Clinical Immunology, 2019, p1--
Leshem, Y.A., Bissonnette, R., Paul, C., Silverberg, J.I., Irvine, A.D., Paller, A.S., Cork, M.J., Guttman-Yassky, E., Optimization of placebo use in clinical trials with systemic treatments for atopic dermatitis: an International Eczema Council survey-based position statement, Journal of the European Academy of Dermatology and Venereology, 33, (5), 2019, p807-815
Harkins, C.P., Holden, M.T.G., Irvine, A.D., Antimicrobial resistance in atopic dermatitis: Need for an urgent rethink, Annals of Allergy, Asthma and Immunology, 2019
F.M. Vermeulen, L.A.A. Gerbens, A.L. Bosma, C.J. Apfelbacher, A.D. Irvine, B.W.M. Arents, S. Barbarot, M. Deleuran, L.F. Eichenfield, A. Manca, J. Schmitt, C. Vestergaard, D. Wall, S. Weidinger, M.A. Middelkamp"Hup, P.I. Spuls, C. Flohr, TRE atment of AT opic eczema ( TREAT ) Registry Taskforce: consensus on how and when to measure the core dataset for atopic eczema treatment research registries, British Journal of Dermatology, 181, (3), 2019, p492--504
Paller, A.S., Spergel, J.M., Mina-Osorio, P., Irvine, A.D., The atopic march and atopic multimorbidity: Many trajectories, many pathways, Journal of Allergy and Clinical Immunology, 143, (1), 2019, p46-55
Ballin, N., Hotz, A., Bourrat, E., Küsel, J., Oji, V., Bouadjar, B., Brognoli, D., Hickman, G., Heinz, L., Vabres, P., Marrakchi, S., Leclerc-Mercier, S., Irvine, A., Tadini, G., Hamm, H., Has, C., Blume-Peytavi, U., Mitter, D., Reitenbach, M., Hausser, I., Zimmer, A.D., Alter, S., Fischer, J., Genetical, clinical, and functional analysis of a large international cohort of patients with autosomal recessive congenital ichthyosis due to mutations in NIPAL4, Human Mutation, 40, (12), 2019, p2318-2333
Verma, N.K., van Steensel, M.A.M., Prasannan, P., Poh, Z.S., Irvine, A.D., Oon, H.H., Common skin diseases: Chronic inflammatory and autoimmune disorders, Imaging Technologies and Transdermal Delivery in Skin Disorders, 2019, p35-59
Nicholas Stefanovic, Carsten Flohr, Alan D. Irvine, The exposome in atopic dermatitis, Allergy, 2019
Clowry, J., Irvine, A.D., McLoughlin, R.M., Next-generation anti"Staphylococcus aureus vaccines: A potential new therapeutic option for atopic dermatitis?, Journal of Allergy and Clinical Immunology, 143, (1), 2019, p78-81
Davidson, W.F., Leung, D.Y.M., Beck, L.A., Berin, C.M., Boguniewicz, M., Busse, W.W., Chatila, T.A., Geha, R.S., Gern, J.E., Guttman-Yassky, E., Irvine, A.D., Kim, B.S., Kong, H.H., Lack, G., Nadeau, K.C., Schwaninger, J., Simpson, A., Simpson, E.L., Spergel, J.M., Togias, A., Wahn, U., Wood, R.A., Woodfolk, J.A., Ziegler, S.F., Plaut, M., Report from the National Institute of Allergy and Infectious Diseases workshop on "Atopic dermatitis and the atopic march: Mechanisms and interventions", Journal of Allergy and Clinical Immunology, 2019
Hawkes, C.P., Grimberg, A., Kenny, L.C., Kiely, M., Hourihane, J.O.B., Irvine, A.D., McPhaul, M.J., Caulfield, M.P., Zemel, B.S., Murray, D.M., The relationship between IGF-I and -II concentrations and body composition at birth and over the first 2 months, Pediatric Research, 85, (5), 2019, p687-692
Paller, A.S., Kong, H.H., Seed, P., Naik, S., Scharschmidt, T.C., Gallo, R.L., Luger, T., Irvine, A.D., The microbiome in patients with atopic dermatitis, Journal of Allergy and Clinical Immunology, 143, (1), 2019, p26-35
E. Chasseuil, J.A. McGrath, A. Seo, X. Balguerie, N. Bodak, H. Chasseuil, M. Denis"Musquer, A. Goldenberg, R. Goussot, A.D. Irvine, N.P. Khumalo, M.C. King, S. Küry, D. Lipsker, S. Mallet, B.M. Mayosi, A. Nanda, E. Puzenat, E. Salort"Campana, R. Sidbury, A. Shimamura, S. Bézieau, S. Mercier, S. Barbarot, Dermatological manifestations of hereditary fibrosing poikiloderma with tendon contractures, myopathy and pulmonary fibrosis ( POIKTMP ): a case series of 28 patients, British Journal of Dermatology, 2019
Bosma, A.L., Spuls, P.I., Garcia-Doval, I., Naldi, L., Prieto-Merino, D., Tesch, F., Apfelbacher, C.J., Arents, B.W.M., Barbarot, S., Baselga, E., Deleuran, M., Eichenfield, L.F., Gerbens, L.A.A., Irvine, A.D., Manca, A., Mendes-Bastos, P., Middelkamp-Hup, M.A., Roberts, A., Seneschal, J., Svensson, Å., Thyssen, J.P., Torres, T., Vermeulen, F.M., Vestergaard, C., von Kobyletzki, L.B., Wall, D., Weidinger, S., Schmitt, J., Flohr, C., TREatment of ATopic eczema (TREAT) Registry Taskforce: protocol for a European safety study of dupilumab and other systemic therapies in patients with atopic eczema, British Journal of Dermatology, 2019
Jean"David Bouaziz, Graham S. Ogg, Marjolein de Bruin"Weller, Thomas Bieber, Alan D. Irvine, Brad Shumel, Jérôme Msihid, Ana B. Rossi, Efficacité et sécurité du dupilumab chez des patients adultes atteints de dermatite atopique modérée à sévère ayant des antécédents d"utilisation d"immunosuppresseur : analyse post-hoc de l"étude de phase 3 CAFÉ, Annales de Dermatologie et de Vénéréologie, 146, (12), 2019, pA341 - A342, pA341-A342
L.A.A. Gerbens, C.J. Apfelbacher, A.D. Irvine, S. Barbarot, R.J. Booij, A.E. Boyce, M. Deleuran, L.F. Eichenfield, M.H. Hof, M.A. Middelkamp"Hup, A. Roberts, J. Schmitt, C. Vestergaard, D. Wall, S. Weidinger, P.R. Williamson, C. Flohr, P.I. Spuls, TRE atment of AT opic eczema ( TREAT ) Registry Taskforce: an international Delphi exercise to identify a core set of domains and domain items for national atopic eczema photo" and systemic therapy registries, British Journal of Dermatology, 180, (4), 2019, p790--801
H. Alexander, A.S. Paller, C. Traidl"Hoffmann, L.A. Beck, A. De Benedetto, S. Dhar, G. Girolomoni, A.D. Irvine, P. Spuls, J. Su, J.P. Thyssen, C. Vestergaard, T. Werfel, A. Wollenberg, M. Deleuran, C. Flohr, The role of bacterial skin infections in atopic dermatitis: expert statement and review from the International Eczema Council Skin Infection Group, British Journal of Dermatology, 2019
L.A.A. Gerbens, C.J. Apfelbacher, A.D. Irvine, S. Barbarot, R.J. de Booij, A.E. Boyce, M. Deleuran, L.F. Eichenfield, M.H. Hof, M.A. Middelkamp-Hup, A. Roberts, J. Schmitt, C. Vestergaard, D. Wall, S. Weidinger, P.R. Williamson, C. Flohr, P.I. Spuls, TREatment of ATopic eczema (TREAT) Registry Taskforce: an international Delphi exercise to identify a core set of domains and domain items for national atopic eczema photo- and systemic therapy registries, British Journal of Dermatology, 2018
Twelves, S., Mostafa, A., Dand, N., Burri, E., Farkas, K., Wilson, R., Cooper, H.L., Irvine, A.D., Oon, H.H., Kingo, K., Köks, S., Mrowietz, U., Puig, L., Reynolds, N., Tan, E.S.-T., Tanew, A., Torz, K., Trattner, H., Valentine, M., Wahie, S., Warren, R.B., Wright, A., Bata-Csörg", Z., Szell, M., Griffiths, C.E.M., Burden, A.D., Choon, S.-E., Smith, C.H., Barker, J.N., Navarini, A.A., Capon, F., Clinical and genetic differences between pustular psoriasis subtypes, Journal of Allergy and Clinical Immunology, 2018
Paller, A.S., Czarnowicki, T., Renert-Yuval, Y., Holland, K., Huynh, T., Sadlier, M., McAleer, M.A., Tran, G., Geddes, G.C., Irvine, A.D., Guttman-Yassky, E., The spectrum of manifestations in desmoplakin gene (DSP) spectrin repeat 6 domain mutations: Immunophenotyping and response to ustekinumab, Journal of the American Academy of Dermatology, 78, (3), 2018, p498-505.e2
McCarthy, E.K., ní Chaoimh, C., Kenny, L.C., Hourihane, J.O.B., Irvine, A.D., Murray, D.M., Kiely, M.E., Iron status, body size, and growth in the first 2 years of life, Maternal and Child Nutrition, 14, (1), 2018
Veronika Dvorakova, David Rea, Grainne M. O'Regan, Alan D. Irvine, Generalized lymphatic anomaly successfully treated with long-term, low-dose sirolimus, Pediatric Dermatology, 2018
Lynch, S.A., Crushell, E., Lambert, D.M., Byrne, N., Gorman, K., King, M.D., Green, A., O'Sullivan, S., Browne, F., Hughes, J., Knerr, I., Monavari, A.A., Cotter, M., McConnell, V.P.M., Kerr, B., Jones, S.A., Keenan, C., Murphy, N., Cody, D., Ennis, S., Turner, J., Irvine, A.D., Casey, J., Catalogue of inherited disorders found among the Irish Traveller population, Journal of Medical Genetics, 55, (4), 2018, p233-239
Hawkes, C.P., Murray, D.M., Kenny, L.C., Kiely, M., O'B Hourihane, J., Irvine, A.D., Wu, Z., Argon, Y., Reitz, R.E., McPhaul, M.J., Grimberg, A., Correlation of Insulin-Like Growth Factor-I and -II Concentrations at Birth Measured by Mass Spectrometry and Growth from Birth to Two Months, Hormone Research in Paediatrics, 89, (2), 2018, p122-131
Catriona P. Harkins, Matthew T. G. Holden, Alan D. Irvine, Antimicrobial resistance in atopic dermatitis, Annals of Allergy Asthma & Immunology, 122, (3), 2018, p236 - 240, p236-240
M.A. McAleer, I. Jakasa, G. Hurault, P. Sarvari, W.H.I. McLean, R.J. Tanaka, S. Kezic, A.D. Irvine, Systemic and stratum corneum biomarkers of severity in infant atopic dermatitis include markers of innate and T helper cell-related immunity and angiogenesis, British Journal of Dermatology, 2018
Mohamed, S., Tobin, A.-M., Irvine, A.D., Wall, D.R., O'Hare, N.J., Kechadi, M.-T., The application of data mining to predict the occurrence of short-term adverse events in NB-UVB phototherapy treatments, International Journal of Machine Learning and Computing, 8, (2), 2018, p104-111
Feuillie C, Vitry P, McAleer MA, Kezic S, Irvine AD, Geoghegan JA, Dufrêne YF., Adhesion of Staphylococcus aureus to Corneocytes from Atopic Dermatitis Patients Is Controlled by Natural Moisturizing Factor Levels., mBio, 9, (4), 2018
Hennessy, Á., Hourihane, J.O.B., Malvisi, L., Irvine, A.D., Kenny, L.C., Murray, D.M., Kiely, M.E., Antenatal vitamin D exposure and childhood eczema, food allergy, asthma and allergic rhinitis at 2 and 5 years of age in the atopic disease-specific Cork BASELINE Birth Cohort Study, Allergy: European Journal of Allergy and Clinical Immunology, 73, (11), 2018, p2182-2191
Pigors, M., Common, J.E.A., Wong, X.F.C.C., Malik, S., Scott, C.A., Tabarra, N., Liany, H., Liu, J., Limviphuvadh, V., Maurer-Stroh, S., Tang, M.B.Y., Lench, N., Margolis, D.J., van Heel, D.A., Mein, C.A., Novak, N., Baurecht, H., Weidinger, S., McLean, W.H.I., Irvine, A.D., O'Toole, E.A., Simpson, M.A., Kelsell, D.P., Exome Sequencing and Rare Variant Analysis Reveals Multiple Filaggrin Mutations in Bangladeshi Families with Atopic Eczema and Additional Risk Genes, Journal of Investigative Dermatology, 138, (12), 2018, p2674-2677
Drucker, A.M., Eyerich, K., de Bruin-Weller, M.S., Thyssen, J.P., Spuls, P.I., Irvine, A.D., Girolomoni, G., Dhar, S., Flohr, C., Murrell, D.F., Paller, A.S., Guttman-Yassky, E., Use of systemic corticosteroids for atopic dermatitis: International Eczema Council consensus statement, British Journal of Dermatology, 178, (3), 2018, p768-775
Janna Nousbeck, Maeve A. McAleer, Elaine Kenny, K. Harte, Alan D. Irvine, 757 MiRNA signature in atopic dermatitis, Journal of Investigative Dermatology, 138, (5), 2018, pS129 - S129, pS129-S129
A.D. Irvine, A.P. Jones, P. Beattie, S. Baron, F. Browne, F. Ashoor, L. O'Neill, A. Rosala-Hallas, T. Sach, C. Spowart, L. Taams, C. Walker, M. Wan, N. Webb, P. Williamson, C. Flohr, A randomized controlled trial protocol assessing the effectiveness, safety and cost-effectiveness of methotrexate vs. ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema Trial (TREAT), British Journal of Dermatology, 2018
Hennessy, Á., Ní Chaoimh, C., McCarthy, E.K., Kingston, C., Irvine, A.D., Hourihane, J.O., Kenny, L.C., Murray, D.M., Kiely, M., Variation in iodine food composition data has a major impact on estimates of iodine intake in young children, European Journal of Clinical Nutrition, 72, (3), 2018, p410-419
Simpson, E.L., Reynolds, N.J., Flohr, C., Paller, A.S., Silverberg, J.I., Cork, M.J., Guttman-Yassky, E., Irvine, A.D., Response to "Comment on: `When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council"", Journal of the American Academy of Dermatology, 79, (2), 2018, pe25-e26
Harkins CP, McAleer MA, Bennett D, McHugh M, Fleury OM, Pettigrew KA, Oravcová K, Parkhill J, Proby CM, Dawe RS, Geoghegan JA, Irvine AD, Holden MTG., The widespread use of topical antimicrobials enriches for resistance in Staphylococcus aureus isolated from patients with atopic dermatitis., The British journal of dermatology, 2018
M.A. McAleer, I. Jakasa, N. Raj, C.P.F. O'Donnell, M.E. Lane, A.V. Rawlings, R. Voegeli, W.H.I. McLean, S. Kezic, A.D. Irvine, Early-life regional and temporal variation in filaggrin-derived natural moisturizing factor, filaggrin-processing enzyme activity, corneocyte phenotypes and plasmin activity: implications for atopic dermatitis, British Journal of Dermatology, 2018
S. Mohamed, Anne"Marie Tobin, Alan D. Irvine, Dmitri Wall, Neil O"Hare, Tahar Kechadi, The Application of Data Mining to Predict the Occurrence of Short-Term Adverse Events in NB-UVB Phototherapy Treatments, International Journal of Machine Learning and Computing, 8, (2), 2018, p104 - 111, p104-111
McCarthy, E.K., Murray, D.M., Malvisi, L., Kenny, L.C., O'B Hourihane, J., Irvine, A.D., Kiely, M.E., Antenatal Vitamin D Status Is Not Associated with Standard Neurodevelopmental Assessments at Age 5 Years in a Well-Characterized Prospective Maternal-Infant Cohort, Journal of Nutrition, 148, (10), 2018, p1580-1586
Lovgren, M.-L., McAleer, M.A., Irvine, A.D., Wilson, N.J., Tavadia, S., Schwartz, M.E., Cole, C., Sandilands, A., Smith, F.J.D., Zamiri, M., Mutations in desmoglein 1 cause diverse inherited palmoplantar keratoderma phenotypes: implications for genetic screening, British Journal of Dermatology, 176, (5), 2017, p1345-1350
Geoghegan JA, Irvine AD, Foster TJ., Staphylococcus aureus and Atopic Dermatitis: A Complex and Evolving Relationship., Trends in microbiology, 2017
Murad, A., O'Regan, G., Watson, R., McDermott, M., O'Sullivan, M., Irvine, A.D., Erythema elevatum diutinum in a healthy child, Clinical and Experimental Dermatology, 42, (4), 2017, p434-436
Spuls, P.I., Gerbens, L.A.A., Apfelbacher, C.J., Wall, D., Arents, B.W.M., Barbarot, S., Roberts, A., Deleuran, M., Middelkamp-Hup, M.A., Vestergaard, C., Weidinger, S., Schmitt, J., Irvine, A.D., Flohr, C., The International TREatment of ATopic Eczema (TREAT) Registry Taskforce: An Initiative to Harmonize Data Collection across National Atopic Eczema Photo- and Systemic Therapy Registries, Journal of Investigative Dermatology, 137, (9), 2017, p2014-2016
Kennedy, E.A., Connolly, J., Hourihane, J.O., Fallon, P.G., McLean, W.H.I., Murray, D., Jo, J.-H., Segre, J.A., Kong, H.H., Irvine, A.D., Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year, Journal of Allergy and Clinical Immunology, 139, (1), 2017, p166-172
Veronika Dvorakova, Grainne M. O'Regan, Alan D. Irvine, Methotrexate for Severe Childhood Atopic Dermatitis: Clinical Experience in a Tertiary Center, Pediatric Dermatology, 2017
Kiely, M., O'Donovan, S.M., Kenny, L.C., Hourihane, J.O., Irvine, A.D., Murray, D.M., Vitamin D metabolite concentrations in umbilical cord blood serum and associations with clinical characteristics in a large prospective mother-infant cohort in Ireland, Journal of Steroid Biochemistry and Molecular Biology, 167, 2017, p162-168
Gerbens, L.A.A., Boyce, A.E., Wall, D., Barbarot, S., Booij, R.J., Deleuran, M., Middelkamp-Hup, M.A., Roberts, A., Vestergaard, C., Weidinger, S., Apfelbacher, C.J., Irvine, A.D., Schmitt, J., Williamson, P.R., Spuls, P.I., Flohr, C., TREatment of ATopic eczema (TREAT) Registry Taskforce: Protocol for an international Delphi exercise to identify a core set of domains and domain items for national atopic eczema registries, Trials, 18, (1), 2017
Samuelov, L., Li, Q., Bochner, R., Najor, N.A., Albrecht, L., Malchin, N., Goldsmith, T., Grafi-Cohen, M., Vodo, D., Fainberg, G., Meilik, B., Goldberg, I., Warshauer, E., Rogers, T., Edie, S., Ishida-Yamamoto, A., Burzenski, L., Erez, N., Murray, S.A., Irvine, A.D., Shultz, L., Green, K.J., Uitto, J., Sprecher, E., Sarig, O., SVEP1 plays a crucial role in epidermal differentiation, Experimental Dermatology, 2017
Storan, E.R., Irvine, A.D., Access to Genetic Diagnostics for Genodermatoses: Who Should Get Tested? Why? Who Pays?, Pediatric Dermatology, 34, (1), 2017, p105-108
Soblet, J., Kangas, J., Nätynki, M., Mendola, A., Helaers, R., Uebelhoer, M., Kaakinen, M., Cordisco, M., Dompmartin, A., Enjolras, O., Holden, S., Irvine, A.D., Kangesu, L., Léauté-Labrèze, C., Lanoel, A., Lokmic, Z., Maas, S., McAleer, M.A., Penington, A., Rieu, P., Syed, S., van der Vleuten, C., Watson, R., Fishman, S.J., Mulliken, J.B., Eklund, L., Limaye, N., Boon, L.M., Vikkula, M., Blue Rubber Bleb Nevus (BRBN) Syndrome Is Caused by Somatic TEK (TIE2) Mutations, Journal of Investigative Dermatology, 137, (1), 2017, p207-216
Simpson, E.L., Bruin-Weller, M., Flohr, C., Ardern-Jones, M.R., Barbarot, S., Deleuran, M., Bieber, T., Vestergaard, C., Brown, S.J., Cork, M.J., Drucker, A.M., Eichenfield, L.F., Foelster-Holst, R., Guttman-Yassky, E., Nosbaum, A., Reynolds, N.J., Silverberg, J.I., Schmitt, J., Seyger, M.M.B., Spuls, P.I., Stalder, J.-F., Su, J.C., Takaoka, R., Traidl-Hoffmann, C., Thyssen, J.P., van der Schaft, J., Wollenberg, A., Irvine, A.D., Paller, A.S., When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council, Journal of the American Academy of Dermatology, 77, (4), 2017, p623-633
Fleury, O.M., McAleer, M.A., Feuillie, C., Formosa-Dague, C., Sansevere, E., Bennett, D.E., Towell, A.M., McLean, W.H.I., Kezic, S., Robinson, D.A., Fallon, P.G., Foster, T.J., Dufrêne, Y.F., Irvine, A.D., Geoghegan, J.A., Clumping factor B promotes adherence of Staphylococcus aureus to corneocytes in atopic dermatitis, Infection and Immunity, 85, (6), 2017, ppii: e00994-16
Gilhooley, E., Gormally, S., Irvine, A., Lynch, S.A., Collins, S., FOXN1 Duplication and Congenital Hypertrichosis, Pediatric Dermatology, 34, (2), 2017, pe77-e79
McCarthy, E.K., Kiely, M.E., Hannon, G., Ahearne, C., Kenny, L.C., Hourihane, J.O., Irvine, A.D., Murray, D.M., Microcytosis is associated with low cognitive outcomes in healthy 2-year-olds in a high-resource setting, British Journal of Nutrition, 118, (5), 2017, p360-367
McCarthy, E.K., Kenny, L.C., Hourihane, J.O., Irvine, A.D., Murray, D.M., Kiely, M.E., Impact of maternal, antenatal and birth-associated factors on iron stores at birth: Data from a prospective maternal-infant birth cohort, European Journal of Clinical Nutrition, 71, (6), 2017, p782-787
Hawkes, C.P., Zemel, B.S., Kiely, M., Irvine, A.D., Kenny, L.C., O'B Hourihane, J., Murray, D.M., Body composition within the first 3 months: Optimized correction for length and correlation with BMI at 2 Years, Hormone Research in Paediatrics, 86, (3), 2016, p178-187
Irvine, A.D., Eichenfield, L.F., Friedlander, S.F., Simpson, E.L., Review of Critical Issues in the Pathogenesis of Atopic Dermatitis, Seminars in cutaneous medicine and surgery, 35, (5), 2016, pS89-S91
Satveer K. Mahil, Sophie Twelves, Katalin Farkas, Niovi Setta-Kaffetzi, A. David Burden, Joanna E. Gach, Alan D. Irvine, László Képíró, Maja Mockenhaupt, Hazel H. Oon, Jason Pinner, Annamari Ranki, Marieke M.B. Seyger, Pere Soler-Palacin, Eoin R. Storan, Eugene S. Tan, Laurence Valeyrie-Allanore, Helen S. Young, Richard C. Trembath, Siew-Eng Choon, Marta Szell, Zsuzsanna Bata-Csorgo, Catherine H. Smith, Paola Di Meglio, Jonathan N. Barker, Francesca Capon, AP1S3 Mutations Cause Skin Autoinflammation by Disrupting Keratinocyte Autophagy and Up-Regulating IL-36 Production, Journal of Investigative Dermatology, 136, (11), 2016, p2251--2259
Domínguez-Hüttinger, E., Christodoulides, P., Miyauchi, K., Irvine, A.D., Okada-Hatakeyama, M., Kubo, M., Tanaka, R.J., Mathematical modeling of atopic dermatitis reveals "double-switch" mechanisms underlying 4 common disease phenotypes, Journal of Allergy and Clinical Immunology, 2016
Jessica Strid, W.H. Irwin McLean, Alan D. Irvine, Too Much, Too Little or Just Enough: A Goldilocks Effect for IL-13 and Skin Barrier Regulation?, Journal of Investigative Dermatology, 136, (3), 2016, p561--564
Eichenfield, L.F., Friedlander, S.F., Simpson, E.L., Irvine, A.D., Assessing the New and Emerging Treatments for Atopic Dermatitis, Seminars in cutaneous medicine and surgery, 35, (5), 2016, pS92-S96
Friedlander, S.F., Simpson, E.L., Irvine, A.D., Eichenfield, L.F., The Changing Paradigm of Atopic Dermatitis Therapy, Seminars in cutaneous medicine and surgery, 35, (5), 2016, pS97-S99
Elaine K. McCarthy, Louise C. Kenny, Jonathan O"B Hourihane, Alan D. Irvine, Deirdre M. Murray, Máiréad Kiely, Maternal, antenatal and birth-associated determinants of neonatal iron stores, Proceedings of The Nutrition Society, 75, (OCE3), 2016
O'Donovan SM, O'B Hourihane J, Murray DM, Kenny LC, Khashan AS, Chaoimh CN, Irvine AD, Kiely M, Neonatal adiposity increases the risk of atopic dermatitis during the first year of life., The Journal of allergy and clinical immunology, 137, (1), 2016, p108-17
Kelleher MM, Dunn-Galvin A, Gray C, Murray DM, Kiely M, Kenny L, McLean WH, Irvine AD, Hourihane JO, Skin barrier impairment at birth predicts food allergy at 2 years of age., The Journal of allergy and clinical immunology, 2016
Elizabeth A. Kennedy, Aoife Gallagher, Jonathan O"B Hourihane, Padraic G. Fallon, Deirdre M. Murray, Julie Segre, Heidi H. Kong, Alan D. Irvine, 476 Skin microbiome alterations in infants before clinical atopic dermatitis, Journal of Investigative Dermatology, 136, (5), 2016, pS84 - S84, pS84-S84
Mccarthy, E.K., ní Chaoimh, C., O'B Hourihane, J., Kenny, L.C., Irvine, A.D., Murray, D.M., Kiely, M., Iron intakes and status of 2-year-old children in the Cork BASELINE Birth Cohort Study, Maternal and Child Nutrition, 2016
Carol ní Chaoimh, Elaine K. McCarthy, Deirdre M. Murray, Louise C. Kenny, Alan D. Irvine, Jonathan O"B Hourihane, Máiréad Kiely, Low prevalence of vitamin D deficiency in Irish preschoolers despite northerly latitude and high prevalence of inadequate intakes, Proceedings of The Nutrition Society, 75, (OCE3), 2016
Ní Chaoimh, C., McCarthy, E.K., Hourihane, J.O., Kenny, L.C., Irvine, A.D., Murray, D.M., Kiely, M.E., Low vitamin D deficiency in Irish toddlers despite northerly latitude and a high prevalence of inadequate intakes, European Journal of Nutrition, 2016, p1-12
Bieber, T., Akdis, C., Lauener, R., Traidl-Hoffmann, C., Schmid-Grendelmeier, P., Schäppi, G., Allam, J.-P., Apfelbacher, C., Augustin, M., Beck, L., Biedermann, T., Braun-Fahrländer, C., Chew, F.T., Clavel, T., Crameri, R., Darsow, U., Deleuran, M., Dittlein, D., Duchna, H.-W., Eichenfeld, L., Eyerich, K., Frei, R., Gelmetti, C., Gieler, U., Gilles, S., Glatz, M., Grando, K., Green, J., Gutermuth, J., Guttman-Yassky, E., Hanifin, J., Hijnen, D., Hoetzenecker, W., Irvine, A., Kalweit, A., Katoh, N., Knol, E., Koren, H., Möhrenschlager, M., Münch, D., Novak, N., O'Mahony, L., Paller, A.S., Rhyner, C., Roduit, C., Schiesser, K., Schröder, J., Simon, D., Simon, H.-U., Sokolowska, M., Spuls, P., Stalder, J.-F., Straub, D., Szalai, Z., Taieb, A., Takaoka, R., Todd, G., Todorova, A., Vestergaard, C., Werfel, T., Wollenberg, A., Ring, J., Global Allergy Forum and 3rd Davos Declaration 2015: Atopic dermatitis/Eczema: Challenges and opportunities toward precision medicine, Allergy: European Journal of Allergy and Clinical Immunology, 71, (5), 2016, p588-592
Dvorakova V, Watson RM, Terron-Kwiatkowski A, Andrew N, Irvine AD, Congenital reticular ichthyosiform erythroderma., Clinical and experimental dermatology, 2016
Friedlander, S.F., Simpson, E.L., Irvine, A.D., Eichenfield, L.F., The changing paradigm of atopic dermatitis therapy, Seminars in Cutaneous Medicine and Surgery, 35, 2016, p97S-99S
Janna Nousbeck, Alan D. Irvine, Atopic Dermatitis According to GARP: New Mechanistic Insights in Disease Pathogenesis, Journal of Investigative Dermatology, 136, (12), 2016, p2340--2341
Chaoimh, C., Murray, D.M., Kenny, L.C., Irvine, A.D., O'Hourihane, J.B., Kiely, M., Cord blood leptin and gains in body weight and fat mass during infancy, European Journal of Endocrinology, 175, (5), 2016, p403-410
Simpson, E.L., Irvine, A.D., Eichenfield, L.F., Friedlander, S.F., Update on Epidemiology, Diagnosis, and Disease Course of Atopic Dermatitis, Seminars in cutaneous medicine and surgery, 35, (5), 2016, pS84-S88
Schmitt J, Schwarz K, Baurecht H, Hotze M, Fölster-Holst R, Rodríguez E, Lee YA, Franke A, Degenhardt F, Lieb W, Gieger C, Kabesch M, Nöthen MM, Irvine AD, McLean WH, Deckert S, Stephan V, Schwarz P, Aringer M, Novak N, Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes., 2016
Baurecht H, Hotze M, Brand S, Büning C, Cormican P, Corvin A, Ellinghaus D, Ellinghaus E, Esparza-Gordillo J, Fölster-Holst R, Franke A, Gieger C, Hubner N, Illig T, Irvine AD, Kabesch M, Lee YA, Lieb W, Marenholz I, McLean WH, Morris DW, Mrowietz U, Nair R, Nöthen MM, Novak N, O'Regan GM, Schreiber S, Smith C, Strauch K, Stuart PE, Trembath R, Tsoi LC, Weichenthal M, Barker J, Elder JT, Weidinger S, Cordell HJ, Brown SJ, Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms., American journal of human genetics, 96, (1), 2015, p104-20
Hussain Safia, Berki Dorottya M., Choon Siew-Eng, Burden A. David, Allen Michael H., Arostegui Juan I., Chaves Antonio, Duckworth Michael, Irvine Alan D., Mockenhaupt Maja, Navarini Alexander A., Seyger Marieke M.B., Soler-Palacin Pere, Prins Christa, Valeyrie-Allanore Laurence, Vicente M. Asuncion, Trembath Richard C., Smith Catherine H., Barker Jonathan N., Capon Francesca, IL36RN mutations define a severe autoinflammatory phenotype of generalized pustular psoriasis , Journal of Allergy and Clinical Immunology , 135 , (4 ), 2015, p1067 - 1070.e9
Oosthuizen L, Mc Aleer MA, Watson RM, O"Regan GM, Byrne A, Crispino-O"Connell G, Irvine AD, Nottingham Eczema Severity Scoring tool can identify children at high risk of food allergy to cow"s milk, egg and peanut., 2015
Connor S, O'Brien M, Irvine A, O'Marcaigh A, Smith O, C3-C4 shingles post haematopoietic stem-cell transplantation., 2015
Berki DM, Liu L, Choon SE, Burden AD, Griffiths CE, Navarini AA, Tan ES, Irvine AD, Ranki A, Ogo T, Petrof G, Mahil SK, Duckworth M, Allen MH, Vito P, Trembath RC, McGrath J, Smith CH, Capon F, Barker JN, Activating CARD14 Mutations Are Associated with Generalized Pustular Psoriasis but Rarely Account for Familial Recurrence in Psoriasis Vulgaris., The Journal of investigative dermatology, 135, (12), 2015, p2964-70
Purcell, C., Cant, A., Irvine, A.D., DOCK8 primary immunodeficiency syndrome, The Lancet, 2015
Higgins, E., Al Shehri, T., McAleer, M.A., Conlon, N., Feighery, C., Lilic, D., Irvine, A.D., Use of ruxolitinib to successfully treat chronic mucocutaneous candidiasis caused by gain-of-function signal transducer and activator of transcription 1 (STAT1) mutation, Journal of Allergy and Clinical Immunology, 135, (2), 2015, p551-553
McAleer MA, Pohler E, Smith FJ, Wilson NJ, Cole C, MacGowan S, Koetsier JL, Godsel LM, Harmon RM, Gruber R, Crumrine D, Elias PM, McDermott M, Butler K, Broderick A, Sarig O, Sprecher E, Green KJ, McLean WH, Irvine AD, Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin., The Journal of allergy and clinical immunology, 2015
Riethmuller C, McAleer MA, Koppes SA, Abdayem R, Franz J, Haftek M, Campbell LE, MacCallum SF, McLean WH, Irvine AD, Kezic S, Filaggrin breakdown products determine corneocyte conformation in patients with atopic dermatitis., The Journal of allergy and clinical immunology, 2015
O"Donovan SM, Murray DM, Hourihane JO, Kenny LC, Irvine AD, Kiely M, No association between food allergens in the complementary feeding diet and eczema during the first 12-months in the Cork BASELINE Birth Cohort., 2015
O"Donovan, S.M., Murray, D.M., Hourihane, J.O., Kenny, L.C., Irvine, A.D., Kiely, M., Adherence with early infant feeding and complementary feeding guidelines in the Cork BASELINE Birth Cohort Study, Public Health Nutrition, 2015
Wedgeworth E, Glover M, Irvine AD, Neri I, Baselga Torres E, Clayton TH, Beattie PE, Bjerre JV, Burrows NP, Foelster-Holst R, Hedelund L, Hernandez-Martin A, Audrain H, Bhate K, Brown SJ, Baryschpolec S, Darne S, Durack A, Dvorakova V, Gach J, Goldstraw N, Goodyear H, Grabcyznska S, Greenblatt D, Halpern J, Hearn RM, Hoey S, Hughes B, Jayaraj R, Johansson EK, Lam M, Leech S, O'Regan GM, Morrison D, Porter W, Ramesh R, Schill T, Shaw L, Taylor AE, Taylor R, Thomson J, Tiffin P, Tsakok M, Janmohamed SR, Laguda B, McPherson T, Oranje A, Patrizi A, Ravenscroft J, Shahidullah H, Soloman L, Svensson A, Wahlgren CF, Hoeger PH, Flohr C, Propranolol in the treatment of infantile haemangiomas: Lessons from the European Propranolol In the Treatment of Complicated Haemangiomas (PITCH) Taskforce Survey., The British journal of dermatology, 2015
Chen, Y.-C., Auer-Grumbach, M., Matsukawa, S., Zitzelsberger, M., Themistocleous, A.C., Strom, T.M., Samara, C., Moore, A.W., Cho, L.T.-Y., Young, G.T., Weiss, C., Schabhüttl, M., Stucka, R., Schmid, A.B., Parman, Y., Graul-Neumann, L., Heinritz, W., Passarge, E., Watson, R.M., Hertz, J.M., Moog, U., Baumgartner, M., Valente, E.M., Pereira, D., Restrepo, C.M., Katona, I., Dusl, M., Stendel, C., Wieland, T., Stafford, F., Reimann, F., Von Au, K., Finke, C., Willems, P.J., Nahorski, M.S., Shaikh, S.S., Carvalho, O.P., Nicholas, A.K., Karbani, G., McAleer, M.A., Cilio, M.R., McHugh, J.C., Murphy, S.M., Irvine, A.D., Jensen, U.B., Windhager, R., Weis, J., Bergmann, C., Rautenstrauss, B., Baets, J., De Jonghe, P., Reilly, M.M., Kropatsch, R., Kurth, I., Chrast, R., Michiue, T., Bennett, D.L.H., Woods, C.G., Senderek, J., Erratum: Transcriptional regulator PRDM12 is essential for human pain perception (Nature Genetics (2015) 47 (803-808)), Nature Genetics, 47, (8), 2015
Saunders SP, Moran T, Floudas A, Wurlod F, Kaszlikowska A, Salimi M, Quinn EM, Oliphant CJ, Núñez G, McManus R, Hams E, Irvine AD, McKenzie AN, Ogg GS, Fallon PG, Spontaneous atopic dermatitis is mediated by innate immunity, with the secondary lung inflammation of the atopic march requiring adaptive immunity., The Journal of allergy and clinical immunology, 2015
Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, Strachan DP, Curtin JA, Bønnelykke K, Tian C, Takahashi A, Esparza-Gordillo J, Alves AC, Thyssen JP, den Dekker HT, Ferreira MA, Altmaier E, Sleiman PM, Xiao FL, Gonzalez JR, Marenholz I, Kalb B, Pino-Yanes M, Xu CJ, Carstensen L, Groen-Blokhuis MM, Venturini C, Pennell CE, Barton SJ, Levin AM, Curjuric I, Bustamante M, Kreiner-Møller E, Lockett GA, Bacelis J, Bunyavanich S, Myers RA, Matanovic A, Kumar A, Tung JY, Hirota T, Kubo M, McArdle WL, Henderson AJ, Kemp JP, Zheng J, Smith GD, Rüschendorf F, Bauerfeind A, Lee-Kirsch MA, Arnold A, Homuth G, Schmidt CO, Mangold E, Cichon S, Keil T, Rodríguez E, Peters A, Franke A, Lieb W, Novak N, Fölster-Holst R, Horikoshi M, Pekkanen J, Sebert S, Husemoen LL, Grarup N, de Jongste JC, Rivadeneira F, Hofman A, Jaddoe VW, Pasmans SG, Elbert NJ, Uitterlinden AG, Marks GB, Thompson PJ, Matheson MC, Robertson CF, Ried JS, Li J, Zuo XB, Zheng XD, Yin XY, Sun LD, McAleer MA, O'Regan GM, Fahy CM, Campbell L, Macek M, Kurek M, Hu D, Eng C, Postma DS, Feenstra B, Geller F, Hottenga JJ, Middeldorp CM, Hysi P, Bataille V, Spector T, Tiesler CM, Thiering E, Pahukasahasram B, Yang JJ, Imboden M, Huntsman S, Vilor-Tejedor N, Relton CL, Myhre R, Nystad W, Custovic A, Weiss ST, Meyers DA, Söderhäll C, Melén E, Ober C, Raby BA, Simpson A, Jacobsson B, Holloway JW, Bisgaard H, Sunyer J, Probst-Hensch NM, Williams LK, Godfrey KM, Wang CA, Boomsma DI, Melbye M, Koppelman GH, Jarvis D, McLean WH, Irvine AD, Zhang XJ, Hakonarson H, Gieger C, Burchard EG, Martin NG, Duijts L, Linneberg A, Jarvelin MR, Nöthen MM, Lau S, Hübner N, Lee YA, Tamari M, Hinds DA, Glass D, Brown SJ, Heinrich J, Evans DM, Weidinger S, Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis., Nature genetics, 47, (12), 2015, p1449-56
O'Donovan SM, Murray DM, Hourihane JO, Kenny LC, Irvine AD, Kiely M, Cohort profile: The Cork BASELINE Birth Cohort Study: Babies after SCOPE: Evaluating the Longitudinal Impact on Neurological and Nutritional Endpoints., 2015
Kelleher M, Dunn-Galvin A, Hourihane JO, Murray D, Campbell LE, McLean WH, Irvine AD, Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year., The Journal of allergy and clinical immunology, 135, (4), 2015, p930-5.e1
O'Rafferty, C., O'Regan, G.M., Irvine, A.D., Smith, O.P., Kasabach-Merritt syndrome, kaposiform haemangioendothelioma and platelet blockade, British Journal of Haematology, 2015
Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, Young GT, Weiss C, Schabhüttl M, Stucka R, Schmid AB, Parman Y, Graul-Neumann L, Heinritz W, Passarge E, Watson RM, Hertz JM, Moog U, Baumgartner M, Valente EM, Pereira D, Restrepo CM, Katona I, Dusl M, Stendel C, Wieland T, Stafford F, Reimann F, von Au K, Finke C, Willems PJ, Nahorski MS, Shaikh SS, Carvalho OP, Nicholas AK, Karbani G, McAleer MA, Cilio MR, McHugh JC, Murphy SM, Irvine AD, Jensen UB, Windhager R, Weis J, Bergmann C, Rautenstrauss B, Baets J, De Jonghe P, Reilly MM, Kropatsch R, Kurth I, Chrast R, Michiue T, Bennett DL, Woods CG, Senderek J, Transcriptional regulator PRDM12 is essential for human pain perception., Nature genetics, 47, (7), 2015, p803-8
Baurecht H, Hotze M, Brand S, BÌning C, Cormican P, Corvin A, Ellinghaus D, Ellinghaus E, Esparza-Gordillo J, Fölster-Holst R, Franke A, Gieger C, Hubner N, Illig T, Irvine A.D, Kabesch M, Lee Y.A.E, Lieb W, Marenholz I, McLean W.H.I, Morris D.W, Mrowietz U, Nair R, Nöthen M.M, Novak N, O'Regan G.M, Schreiber S, Smith C, Strauch K, Stuart P.E, Trembath R, Tsoi L.C, Weichenthal M, Barker J, Elder J.T, Weidinger S, Cordell H.J, Brown S.J, Erratum: Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms (American Journal of Human Genetics (2015) 96 (104-120)), American Journal of Human Genetics, 97, (6), 2015, p933-
O'Rafferty, C., O'Regan, G.M., Irvine, A.D., Smith, O.P., Recent advances in the pathobiology and management of Kasabach-Merritt phenomenon, British Journal of Haematology, 2015
Quinn, N., Macmahon, J., Irvine, A.D., Lowry, C., Sweet syndrome revealing Systemic Lupus Erythematosus, Irish Medical Journal, 108, (2), 2015
Mercier S, Küry S, Salort-Campana E, Magot A, Agbim U, Besnard T, Bodak N, Bou-Hanna C, Bréhéret F, Brunelle P, Caillon F, Chabrol B, Cormier-Daire V, David A, Eymard B, Faivre L, Figarella-Branger D, Fleurence E, Ganapathi M, Gherardi R, Goldenberg A, Hamel A, Igual J, Irvine AD, Israël-Biet D, Kannengiesser C, Laboisse C, Le Caignec C, Mahé JY, Mallet S, MacGowan S, McAleer MA, McLean I, Méni C, Munnich A, Mussini JM, Nagy PL, Odel J, O'Regan GM, Péréon Y, Perrier J, Piard J, Puzenat E, Sampson JB, Smith F, Soufir N, Tanji K, Thauvin C, Ulane C, Watson RM, Khumalo NP, Mayosi BM, Barbarot S, Bézieau S, Expanding the clinical spectrum of hereditary fibrosing poikiloderma with tendon contractures, myopathy and pulmonary fibrosis due to FAM111B mutations., Orphanet journal of rare diseases, 10, 2015, p135
Hussain, S., Berki, D.M., Choon, S.-E., Burden, A.D., Allen, M.H., Arostegui, J.I., Chaves, A., Duckworth, M., Irvine, A.D., Mockenhaupt, M., Navarini, A.A., Seyger, M.M.B., Soler-Palacin, P., Prins, C., Valeyrie-Allanore, L., Vicente, M.A., Trembath, R.C., Smith, C.H., Barker, J.N., Capon, F., IL36RN mutations define a severe autoinflammatory phenotype of generalized pustular psoriasis: To the editor, Journal of Allergy and Clinical Immunology, 135, (4), 2015, p1067-1070.e9
Kiely C, Devaney D, Fischer J, Lenane P, Irvine AD, Ichthyosis prematurity syndrome: a case report and review of known mutations., Pediatric dermatology, 31, (4), 2014, p517-8
Nason GJ, Baker JF, Seoighe D, Irvine AD, McDermott M, Orr D, Capra M, Kelly PM, Congenital-infantile fibrosarcoma of the foot--avoidance of amputation., Irish medical journal, 107, (5), 2014, p148-9
Thawer-Esmail F, Jakasa I, Todd G, Wen Y, Brown SJ, Kroboth K, Campbell LE, O'Regan GM, McLean WH, Irvine AD, Kezic S, Sandilands A, South African amaXhosa patients with atopic dermatitis have decreased levels of filaggrin breakdown products but no loss-of-function mutations in filaggrin., The Journal of allergy and clinical immunology, 133, (1), 2014, p280-282.e2
Foley C, Moran B, McMenamin M, McDermott R, Ormond P, Irvine AD, Spontaneous regression of cutaneous metastases of squamous cell carcinoma., QJM : monthly journal of the Association of Physicians, 107, (1), 2014, p61-3
Gallagher, A., Hourihane, J.O.B., Kenny, L.C., Irvine, A.D., Khashan, A.S., A longitudinal study of skin barrier function in pregnancy and the postnatal period, Obstetric Medicine, 7, (4), 2014, p156-159
Cole C, Kroboth K, Schurch NJ, Sandilands A, Sherstnev A, O'Regan GM, Watson RM, Irwin McLean WH, Barton GJ, Irvine AD, Brown SJ, Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis., The Journal of allergy and clinical immunology, 134, (1), 2014, p82-91
Courtney, D.G., Atkinson, S.D., Allen, E.H.A., Moore, J.E., Walsh, C.P., Pedrioli, D.M.L., MacEwen, C.J., Pellegrini, G., Maurizi, E., Serafini, C., Fantacci, M., Liao, H., Irvine, A.D., McIrwin Lean, W.H., Tara Moore, C.B., SiRNA silencing of the mutant keratin 12 allele in corneal limbal epithelial cells grown from patients with Meesmann's epithelial corneal dystrophy, Investigative Ophthalmology and Visual Science, 55, (5), 2014, p3352-3360
Hughes, R., McAleer, M., Watson, R., Collins, S., Irvine, A., White, M., Rapidly involuting congenital hemangioma with pustules: Two cases, Pediatric Dermatology, 31, (3), 2014, p398-400
Irvine AD, Crossing barriers; restoring barriers? Filaggrin protein replacement takes a bow., The Journal of investigative dermatology, 134, (2), 2014, p313-4
Irvine AD, Commentary: Methotrexate and ciclosporin in the treatment of severe eczema in children., The British journal of dermatology, 170, (3), 2014, p499-500
Kelleher M, Dunn AG, Irvine A, Smith H, Hourihane OJ, O08 - Increased early life Transepidermal Water Loss (TEWL) values can predate atopic dermatitis in asymptomatic infants: results from the BASELINE study., 2014
Courtney DG, Atkinson SD, Allen EH, Moore JE, Walsh CP, Pedrioli DM, MacEwen CJ, Pellegrini G, Maurizi E, Serafini C, Fantacci M, Liao H, Irvine AD, McLean WH, Moore CB, siRNA silencing of the mutant keratin 12 allele in corneal limbal epithelial cells grown from patients with Meesmann's epithelial corneal dystrophy., Investigative ophthalmology & visual science, 55, (5), 2014, p3352-60
Salinas, C.F., Irvine, A.D., Itin, P.H., Di Giovanna, J.J., Schneider, H., Clarke, A.J., McGovern, L.S., Fete, M., Second international conference on a classification of ectodermal dysplasias: Development of a multiaxis model, American Journal of Medical Genetics, Part A, 164, (10), 2014, p2482-2489
Alan D. Irvine, Role of Filaggrin Mutations in Human Disease and Allergic Sensitization, 2013 AAAAI Annual Meeting (February 22 - 26, 2013), 2013
Samuelov L, Sarig O, Harmon RM, Rapaport D, Ishida-Yamamoto A, Isakov O, Koetsier JL, Gat A, Goldberg I, Bergman R, Spiegel R, Eytan O, Geller S, Peleg S, Shomron N, Goh CS, Wilson NJ, Smith FJ, Pohler E, Simpson MA, McLean WH, Irvine AD, Horowitz M, McGrath JA, Green KJ, Sprecher E, Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting., Nature genetics, 45, (10), 2013, p1244-8
McAleer MA, Irvine AD, The multifunctional role of filaggrin in allergic skin disease., The Journal of allergy and clinical immunology, 131, (2), 2013, p280-91
Foley CC, McMenamin M, Gordon KD, Irvine AD, An unusual case of genital swelling., Clinical and experimental dermatology, 38, (8), 2013, p946-8
Flohr C, Irvine AD, Systemic therapies for severe atopic dermatitis in children and adults., The Journal of allergy and clinical immunology, 132, (3), 2013, p774-774.e6
Fahy CM, Fortune A, Quinn F, McMenamin ME, Browne PV, Langabeer S, McCarron S, Hayden P, Marren P, Ni Chonghaile M, Irvine AD, Vandenberghe E, Barnes L, Development of mycosis fungoides after bone marrow transplantation for chronic myeloid leukaemia; transmission from allogeneic donor., The British journal of dermatology, 2013
Langan SM, Irvine AD, Childhood eczema and the importance of the physical environment., The Journal of investigative dermatology, 133, (7), 2013, p1706-9
Wall D, McMenamin M, O'Mahony D, Irvine AD, Kaposi sarcoma in an patient with atopic dermatitis treated with ciclosporin., BMJ case reports, 2013, 2013
Higgins E, Capra M, Schwartz ME, Smith FJD, McLean WHI, Irvine AD, Resolution of the plantar hyperkeratosis of pachyonychia congenita during chemotherapy for Ewing sarcoma , British Journal of Dermatology , 169 , (6 ), 2013, p1357 - 1360
Weidinger S, Willis-Owen SA, Kamatani Y, Baurecht H, Morar N, Liang L, Edser P, Street T, Rodriguez E, O'Regan GM, Beattie P, Fölster-Holst R, Franke A, Novak N, Fahy CM, Winge MC, Kabesch M, Illig T, Heath S, Söderhäll C, Melén E, Pershagen G, Kere J, Bradley M, Lieden A, Nordenskjold M, Harper JI, McLean WH, Brown SJ, Cookson WO, Lathrop GM, Irvine AD, Moffatt MF, A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis., Human molecular genetics, 22, (23), 2013, p4841-56
Conte MI, Pescatore A, Paciolla M, Esposito E, Miano MG, Lioi MB, McAleer MA, Giardino G, Pignata C, Irvine AD, Scheuerle AE, Royer G, Hadj-Rabia S, Bodemer C, Bonnefont JP, Munnich A, Smahi A, Steffann J, Fusco F, Ursini MV, Insight into IKBKG/NEMO Locus: Report of New Mutations and Complex Genomic Rearrangements Leading to Incontinentia Pigmenti Disease., Human mutation, 2013
Maeve Kelleher, Audrey Dunn Galvin, Deirdre M. Murray, Alan D. Irvine, Jonathan O"B Hourihane, Baseline Team, Early Life Transepidermal Water Loss (TEWL) Values Can Predate Atopic Dermatitis At Six and Twelve Months in Asymptomatic Infants: Results From the Baseline Study, Journal of Allergy and Clinical Immunology, 131, (2), 2013, pAB102 - AB102, pAB102-AB102
Revencu N, Boon LM, Mendola A, Cordisco MR, Dubois J, Clapuyt P, Hammer F, Amor DJ, Irvine AD, Baselga E, Dompmartin A, Syed S, Martin-Santiago A, Ades L, Collins F, Smith J, Sandaradura S, Barrio VR, Burrows PE, Blei F, Cozzolino M, Brunetti-Pierri N, Vicente A, Abramowicz M, Désir J, Vilain C, Chung WK, Wilson A, Gardiner CA, Dwight Y, Lord DJ, Fishman L, Cytrynbaum C, Chamlin S, Ghali F, Gilaberte Y, Joss S, Boente Mdel C, Léauté-Labrèze C, Delrue MA, Bayliss S, Martorell L, González-Enseñat MA, Mazereeuw-Hautier J, O'Donnell B, Bessis D, Pyeritz RE, Salhi A, Tan OT, Wargon O, Mulliken JB, Vikkula M, RASA1 mutations and associated phenotypes in 68 families with capillary malformation-arteriovenous malformation., Human mutation, 34, (12), 2013, p1632-41
Baclig, A.C., Bakker Schut, T.C., O'Regan, G.M., Irvine, A.D., McLean, W.H.I., Puppels, G.J., Caspers, P.J., Possibilities for human skin characterization based on strongly reduced Raman spectroscopic information, Journal of Raman Spectroscopy, 44, (3), 2013, p340-345
McLean WH, Irvine AD, Old King Coal - molecular mechanisms underlying an ancient treatment for atopic eczema., The Journal of clinical investigation, 2013, p1-3
Ellinghaus D, Baurecht H, Esparza-Gordillo J, Rodríguez E, Matanovic A, Marenholz I, Hübner N, Schaarschmidt H, Novak N, Michel S, Maintz L, Werfel T, Meyer-Hoffert U, Hotze M, Prokisch H, Heim K, Herder C, Hirota T, Tamari M, Kubo M, Takahashi A, Nakamura Y, Tsoi LC, Stuart P, Elder JT, Sun L, Zuo X, Yang S, Zhang X, Hoffmann P, Nöthen MM, Fölster-Holst R, Winkelmann J, Illig T, Boehm BO, Duerr RH, Büning C, Brand S, Glas J, McAleer MA, Fahy CM, Kabesch M, Brown S, McLean WH, Irvine AD, Schreiber S, Lee YA, Franke A, Weidinger S, High-density genotyping study identifies four new susceptibility loci for atopic dermatitis., Nature genetics, 45, (7), 2013, p808-12
Kelleher MM, O'Carroll M, Gallagher A, Murray DM, Dunn Galvin A, Irvine AD, Hourihane JO, Newborn transepidermal water loss values: a reference dataset., Pediatric dermatology, 30, (6), 2013, p712-6
Asai, Yuka Greenwood, Celia Hull, Peter R. Alizadehfar, Reza Ben-Shoshan, Moshe Brown, Sara J. Campbell, Linda Michel, Deborah L. Bussières, Johanne Rousseau, François Fujiwara, T. Mary Morgan, Kenneth Irvine, Alan D. McLean, W.H. Irwin Clarke, Ann , Filaggrin gene mutation associations with peanut allergy persist despite variations in peanut allergy diagnostic criteria or asthma status , Journal of Allergy and Clinical Immunology , 132 , (1 ), 2013, p239 - 242.e7
Stewart, Jessica M., Sanson-Fisher, Rob W., Eades, Sandra J., Mealing, Nicole M., Strategies for increasing high-quality intervention research in Aboriginal and Torres Strait Islander health: views of leading researchers, Medical Journal of Australia, 192, (10), 2013, p612-615
Saunders, S.P., Goh, C.S.M., Brown, S.J., Palmer, C.N.A., Porter, R.M., Cole, C., Campbell, L.E., Gierlinski, M., Barton, G.J., Schneider, G., Balmain, A., Prescott, A.R., Weidinger, S., Baurecht, H., Kabesch, M., Gieger, C., Lee, Y.-A., Tavendale, R., Mukhopadhyay, S., Turner, S.W., Madhok, V.B., Sullivan, F.M., Relton, C., Burn, J., Meggitt, S., Smith, C.H., Allen, M.A., Barker, J.N.W.N., Reynolds, N.J., Cordell, H.J., Irvine, A.D., McLean, W.H.I., Sandilands, A., Fallon, P.G., Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects, Journal of Allergy and Clinical Immunology, 132, (5), 2013, p1121-1129
Hackett BC, Phelan E, Ryan A, Kenny L, Murphy M, Irvine AD, Watson RM, Use of Systemic Corticosteroids in Management of a Large Congenital Haemangioma of the Scalp., Pediatric dermatology, 2012
Pohler E, Mamai O, Hirst J, Zamiri M, Horn H, Nomura T, Irvine AD, Moran B, Wilson NJ, Smith FJ, Goh CS, Sandilands A, Cole C, Barton GJ, Evans AT, Shimizu H, Akiyama M, Suehiro M, Konohana I, Shboul M, Teissier S, Boussofara L, Denguezli M, Saad A, Gribaa M, Dopping-Hepenstal PJ, McGrath JA, Brown SJ, Goudie DR, Reversade B, Munro CS, McLean WH, Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma., Nature genetics, 44, (11), 2012, p1272-6
Tsoi LC, Spain SL, Knight J, Ellinghaus E, Stuart PE, Capon F, Ding J, Li Y, Tejasvi T, Gudjonsson JE, Kang HM, Allen MH, McManus R, Novelli G, Samuelsson L, Schalkwijk J, Ståhle M, Burden AD, Smith CH, Cork MJ, Estivill X, Bowcock AM, Krueger GG, Weger W, Worthington J, Tazi-Ahnini R, Nestle FO, Hayday A, Hoffmann P, Winkelmann J, Wijmenga C, Langford C, Edkins S, Andrews R, Blackburn H, Strange A, Band G, Pearson RD, Vukcevic D, Spencer CC, Deloukas P, Mrowietz U, Schreiber S, Weidinger S, Koks S, Kingo K, Esko T, Metspalu A, Lim HW, Voorhees JJ, Weichenthal M, Wichmann HE, Chandran V, Rosen CF, Rahman P, Gladman DD, Griffiths CE, Reis A, Kere J, Nair RP, Franke A, Barker JN, Abecasis GR, Elder JT, Trembath RC, Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity., Nature genetics, 44, (12), 2012, p1341-1348
Kezic S, O'Regan GM, Lutter R, Jakasa I, Koster ES, Saunders S, Caspers P, Kemperman PM, Puppels GJ, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Fallon PG, McLean WH, Irvine AD, Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency., The Journal of allergy and clinical immunology, 129, (4), 2012, p1031-9.e1
McLean WH, Irvine AD, Heritable filaggrin disorders: the paradigm of atopic dermatitis., The Journal of investigative dermatology, 132, (E1), 2012, pE20-1
Irvine AD, Double trouble: homozygous dominant mutations and hair loss in pachyonychia congenita., The Journal of investigative dermatology, 132, (7), 2012, p1757-9
Brown SJ, Kroboth K, Sandilands A, Campbell LE, Pohler E, Kezic S, Cordell HJ, McLean WH, Irvine AD, Intragenic copy number variation within filaggrin contributes to the risk of atopic dermatitis with a dose-dependent effect., The Journal of investigative dermatology, 132, (1), 2012, p98-104
Crushell E, O'Leary D, Irvine AD, O'Shea A, Mayne PD, Reardon W, Methylenetetrahydrofolate reductase (MTHFR) deficiency presenting as a rash., American journal of medical genetics. Part A, 158A, (9), 2012, p2254-7
Krawczyk J, McDermott M, Irvine AD, O'Marcaigh A, Storey L, Smith O, Skin involvement in Down syndrome transient abnormal myelopoiesis., British journal of haematology, 157, (3), 2012, p280
Sinead M. O"Donovan, Deirdre M. Murray, Jonathan O"B Hourihane, Louise C. Kenny, Alan D. Irvine, Máiréad Kiely, Early feeding and weaning in Irish infants in the Cork baseline birth cohort study, Proceedings of The Nutrition Society, 71, (OCE2), 2012
Porokeratoses in, editor(s)Goldsmith LA, Katz SI, Gilchrest BA, Paller A, Leffell DJ , Fitzpatrick's Dermatology in General Medicine , New York , McGraw Hill, 2012, ppxxx - xxx, [O'Regan GM, Irvine AD]
Knight J, Spain SL, Capon F, Hayday A, Nestle FO, Clop A, Wellcome Trust Case Control Consortium, Genetic Analysis of Psoriasis Consortium§, I-chip for Psoriasis Consortium, Barker JN. Weale ME, Trembath RC, Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis, Human Molecular Genetics, 21, (23), 2012, p5185 - 5192
Brown SJ, Kroboth K, Sandilands A, Campbell LE, Pohler E, Kezic S, Cordell HJ, McLean WH, Irvine AD., Intragenic Copy Number Variation within Filaggrin Contributes to the Risk of Atopic Dermatitis with a Dose-Dependent Effect, Journal of Investigative Dermatology, 132, 2012, p98-104
Sandilands Aileen, Brown Sara J, Goh Christabelle S, Pohler Elizabeth, Wilson Neil J, Campbell Linda E, Miyamoto Kenichi, Kubo Akiharu, Irvine Alan D, Thawer-Esmail Fatema, Mutations in the SASPase gene (ASPRV1) are not associated with atopic eczema or clinically dry skin , The Journal of investigative dermatology , 132 , (5 ), 2012, p1507 -
McAleer MA, Flohr C, Irvine AD, Management of difficult and severe eczema in childhood., BMJ (Clinical research ed.), 345, 2012, pe4770
Irvine, A.D., Hoeger, P.H., Yan, A.C., Preface to the third edition, Harper's Textbook of Pediatric Dermatology: Third Edition, 1, 2011
Miajlovic H, Fallon PG, Irvine AD, Foster TJ., Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus, Journal of Allergy and Clinical Immunology, 126, (6), 2011, p1184-1190
Bracken J, Robinson I, Snow A, Watson R, Irvine AD, Rea D, Phelan E, PHACE syndrome: MRI of intracerebral vascular anomalies and clinical findings in a series of 12 patients., Pediatric radiology, 41, (9), 2011, p1129-38
Atopic Dermatitis: Genetics in, editor(s)Irvine AD, Hoeger PH, Yan A , Textbook of Pediatric Dermatology , London , Blackwell-Wiley, 2011, pp1 - 23, [Weidinger S, Irvine AD ]
Liao H, Irvine AD, Macewen CJ, Weed KH, Porter L, Corden LD, Gibson AB, Moore JE, Smith FJ, McLean WH, Moore CB, Development of Allele-Specific Therapeutic siRNA in Meesmann Epithelial Corneal Dystrophy., PloS one, 6, (12, e28582), 2011
Irvine, A.D., Hoeger, P.H., Yan, A.C., Harper's Textbook of Pediatric Dermatology: Third Edition, Harper's Textbook of Pediatric Dermatology: Third Edition, 1-2, 2011
Fleming P, Fitzgerald K, Watson R, Irvine A. , Response to "dental caries as a side effect of infantile hemangioma treatment with propanolol solution", Pediatric Dermatology, 28, 2011, p602 - 602
Pediatric Dermatology in, editor(s)Irvine AD, Hoeger PH, Yan A , Harper's Textbook of Pediatric Dermatology , London, Blackwell-Wiley, 2011, pp2816 - [Weidinger S, Irvine AD]
Keohane, C., Bacon, C.L., Moran, B., Irvine, A.D., Smith, O.P., Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome induced by cidofovir, Pediatric Transplantation, 15, (1), 2011
Ricciardo B, Irvine A, McDermott M, Ryan J, Collins S, A case of congenital solitary Langerhans cell histiocytoma., The Australasian journal of dermatology, 52, (2), 2011, pe1-3
Sinead M. O"Donovan, Jonathan O"B Hourihane, Louise C. Kenny, Deirdre M. Murray, Alan D. Irvine, Máiréad Kiely, Descriptive analysis of weaning practices and eczema prevalence in Irish infants in the Cork BASELINE birth cohort study, Proceedings of The Nutrition Society, 70, (OCE3), 2011
Chen H, Common JE, Haines RL, Balakrishnan A, Brown SJ, Goh CS, Cordell HJ, Sandilands A, Campbell LE, Kroboth K, Irvine AD, Goh DL, Tang MB, van Bever HP, Giam YC, McLean WH, Lane EB, Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations., The British journal of dermatology, 165, (1), 2011, p106-14
Robert P. Doyle, Alan D. Irvine, Jonathan O"B Hourihane, Evolution of Skin Barrier Function in the First Year of Life, Journal of Allergy and Clinical Immunology, 127, (2), 2011, pAB34 - AB34, pAB34-AB34
Kezic S, O'Regan GM, Yau N, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Rowland M, McLean WH, Irvine AD, Levels of filaggrin degradation products are influenced by both filaggrin genotype and atopic dermatitis severity., Allergy, 66, (7), 2011, p934-40
Ectodermal Dysplasias in, editor(s)Irvine AD, Hoeger PH, Yan A , Textbook of Pediatric Dermatology, London, Blackwell‐Wiley, 2011, pp1 - 127, [Asai Y, Irvine AD ]
Irvine, A.D., Hoeger, P.H., Yan, A.C., Preface to the third edition, Harper's Textbook of Pediatric Dermatology: Third Edition, 1, 2011
Irvine AD, McLean WH, Leung DY, Filaggrin mutations associated with skin and allergic diseases., The New England journal of medicine, 365, (14), 2011, p1315-27
Brown SJ, Asai Y, Cordell HJ, Campbell LE, Zhao Y, Liao H, Northstone K, Henderson J, Alizadehfar R, Ben-Shoshan M, Morgan K, Roberts G, Masthoff LJ, Pasmans SG, van den Akker PC, Wijmenga C, Hourihane JO, Palmer CN, Lack G, Clarke A, Hull PR, Irvine AD, McLean WH, Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy., The Journal of allergy and clinical immunology, 127, (3), 2011, p661-7
Scurr I, Wilson L, Lees M, Robertson S, Kirk E, Turner A, Morton J, Kidd A, Shashi V, Stanley C, Berry M, Irvine AD, Goudie D, Turner C, Brewer C, Smithson S, Cantú syndrome: report of nine new cases and expansion of the clinical phenotype., American journal of medical genetics. Part A, 155A, (3), 2011, p508-18
Weidinger, S., Irvine, A.D., Genetics of Atopic Dermatitis, Harper's Textbook of Pediatric Dermatology: Third Edition, 1, 2011, p1-17
Conor McCarthy, Aoife Gallagher, Hazel Smith, Jennifer Connolly, E Cobbe, Donal Sheehan, Deirdre M. Murray, Alan D. Irvine, Jonathan O"B Hourihane, A Longitudinal Cohort Study of Transepidermal Water Loss in the First Six Months of Life as a Predictor of Subsequent Atopic Dermatitis, Pediatric Research, 70, 2011, p293 - 293, p293-293
Clericuzio C, Harutyunyan K, Jin W, Erickson RP, Irvine AD, McLean WH, Wen Y, Bagatell R, Griffin TA, Shwayder TA, Plon SE, Wang LL, Identification of a novel C16orf57 mutation in Athabaskan patients with Poikiloderma with Neutropenia., American journal of medical genetics. Part A, 155A, (2), 2011, p337-42
Hawkes CP, Hourihane JO, Kenny LC, Irvine AD, Kiely M, Murray DM, Gender- and gestational age-specific body fat percentage at birth., Pediatrics, 128, (3), 2011, pe645-51
Irvine, A.D., Hoeger, P.H., Yan, A.C., Harper's Textbook of Pediatric Dermatology: Third Edition, Harper's Textbook of Pediatric Dermatology: Third Edition, 1-2, 2011
O'Regan GM, Irvine AD, The role of filaggrin in the atopic diathesis., Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 40, (7), 2010, p965-72
Other Syndromes associated with Ichthyosis in, editor(s)Schnacher L and Hansen R , Pediatric Dermatology , London, Mosby, 2010, pp612 - 614, [Irvine AD]
Michael Barrett, Jonathan O"B Hourihane, Máiréad Kiely, Louise C. Kenny, Alan D. Irvine, Deirdre M. Murray, 413 Newborn Body Composition on Day Two of Life Measured Using Airdisplacement Body Plethysmography, Pediatric Research, 68, 2010, p212 - 212, p212-212
Peeling Skin Syndrome in, editor(s)Schnacher L and Hansen R , Pediatric Dermatology, London, Mosby, 2010, pp1 - 23, [Irvine AD]
Hackett BC, Fitzgerald D, Watson RM, Hol F.A, Irvine AD, Genotype-Phenotype Correlations with TGM1: Clustering of Mutations in the Bathing Suit Ichthyosis and Self Healing Collodion Baby Variants of Lamellar Ichthyosis, British Journal of Dermatology, 162, (2), 2010, p448-451
Ichthyosis Vulgaris in, editor(s)Schnacher L and Hansen R , Pediatric Dermatology, London, Mosby, 2010, pp578 - 580, [Irvine AD ]
O'Regan GM, Kemperman PMJH, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Rowland M, Puppels GJ, McLean WHI, Caspers PJ Irvine AD, Raman Profiles of the Stratum Corneum Define Three FLG Genotype-determined Atopic Dermatitis Endophenotypes , Journal of Allergy and Clinical Immunology, 126, 2010, p574-580
Mark O"Carroll, Aoife Gallagher, David K. Murray, Barbara A. Murphy, Alan D. Irvine, Jonathan O"B Hourihane, Correlation of Neonatal Skin Barrier Function with Family Atopy Profile, Journal of Allergy and Clinical Immunology, 125, (2), 2010, pAB92 - AB92, pAB92-AB92
O'Regan GM, Campbell LE, Cordell HJ, Irvine AD, McLean WHI, Brown SJ, Chromosome 11q13.5 variant associated with childhood eczema; an effect supplementary to filaggrin mutations, Journal of Allergy and Clinical Immunology, 125, 2010, p170-174
Bergboer JG, Zeeuwen PL, Irvine AD, Weidinger S, Giardina E, Novelli G, Heijer MD, Rodriguez E, Illig T, Riveira-Munoz E, Campbell LE, Tyson J, Dannhauser EN, O'Regan GM, Galli E, Klopp N, Koppelman GH, Novak N, Estivill X, McLean WH, Postma DS, Armour JA, Schalkwijk J, Deletion of Late Cornified Envelope 3B and 3C Genes Is Not Associated with Atopic Dermatitis, Journal of Investigative Dermatology, 130, 2010, p2057-2061
Moriarty B, Bourke JF, Fitzgibbon J, Irvine AD, An unusual rash in a neonate. X-linked dominant ichthyosis (XLDI)., Clinical and experimental dermatology, 35, (3), 2010, pe62-4
Moriarty, B., Bourke, J.F., Fitzgibbon, J., Irvine, A.D., An unusual rash in a neonate, Clinical and Experimental Dermatology, 35, (3), 2010
O'Regan GM, Campbell LE, Cordell HJ, Irvine AD, McLean WH, Brown SJ, Chromosome 11q13.5 variant associated with childhood eczema: an effect supplementary to filaggrin mutations., The Journal of allergy and clinical immunology, 125, (1), 2010, p170-4.e1-2
Strange A, Capon F, Spencer CC, Knight J, Weale ME, Allen MH, Barton A, Band G, Bellenguez C, Bergboer JG, Blackwell JM, Bramon E, Bumpstead SJ, Casas JP, Cork MJ, Corvin A, Deloukas P, Dilthey A, Duncanson A, Edkins S, Estivill X, Fitzgerald O, Freeman C, Giardina E, Gray E, Hofer A, Hüffmeier U, Hunt SE, Irvine AD, Jankowski J, Kirby B, Langford C, Lascorz J, Leman J, Leslie S, Mallbris L, Markus HS, Mathew CG, McLean WH, McManus R, Mössner R, Moutsianas L, Naluai AT, Nestle FO, Novelli G, Onoufriadis A, Palmer CN, Perricone C, Pirinen M, Plomin R, Potter SC, Pujol RM, Rautanen A, Riveira-Munoz E, Ryan AW, Salmhofer W, Samuelsson L, Sawcer SJ, Schalkwijk J, Smith CH, Ståhle M, Su Z, Tazi-Ahnini R, Traupe H, Viswanathan AC, Warren RB, Weger W, Wolk K, Wood N, Worthington J, Young HS, Zeeuwen PL, Hayday A, Burden AD, Griffiths CE, Kere J, Reis A, McVean G, Evans DM, Brown MA, Barker JN, Peltonen L, Donnelly P, Trembath RC, A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1., Nature genetics, 42, (11), 2010, p985-990
O'Regan GM, Kemperman PM, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Rowland M, Puppels GJ, McLean WH, Caspers PJ, Irvine AD, Raman profiles of the stratum corneum define 3 filaggrin genotype-determined atopic dermatitis endophenotypes., The Journal of allergy and clinical immunology, 126, (3), 2010, p574-80.e1
Hou N Liu, Jonathan O"B Hourihane, Louise C. Kenny, Máiréad Kiely, Alan D. Irvine, Deirdre M. Murray, 404 Comparison of Body Fat Estimation Using Skin Fold Thickness Measurement and Simultaneous Air- Displacement Plethysmography at 8 Weeks, Pediatric Research, 68, 2010, p208 - 208, p208-208
Genetics and Genodermatoses in, editor(s)Burns T, Breathnach S, Cox N, Griffiths C , Rook's Textbook of Dermatology, Chichester , Wiley Blackwell, 2010, pp1 - 15.97, [Mellerio JE and Irvine AD]
Bergboer JG, Zeeuwen PL, Irvine AD, Weidinger S, Giardina E, Novelli G, Den Heijer M, Rodriguez E, Illig T, Riveira-Munoz E, Campbell LE, Tyson J, Dannhauser EN, O'Regan GM, Galli E, Klopp N, Koppelman GH, Novak N, Estivill X, McLean WH, Postma DS, Armour JA, Schalkwijk J, Deletion of Late Cornified Envelope 3B and 3C genes is not associated with atopic dermatitis., The Journal of investigative dermatology, 130, (8), 2010, p2057-61
Rodriguez S, Hall AJ, Granell R, McLean WH, Irvine AD, Palmer CN, Smith GD, Henderson J, Day IN, Carrier status for the common R501X and 2282del4 filaggrin mutations is not associated with hearing phenotypes in 5,377 children from the ALSPAC cohort, PLoS ONE, 4, (6), 2009, pe5784
Sandilands, A, Sutherland, C, Irvine, AD, McLean, WH, Filaggrin in the frontline: role in skin barrier function and disease., Journal of Cell Science, 122, (Pt 9), 2009, p1285-1294
Fallon, PG, Sasaki, T, Sandilands, A, Campbell, LE, Saunders, SP, Mangan, NE, Callanan, JJ, Kawasaki, H, Shiohama, A, Kubo, A, Sundberg, JP, Presland, RB, Fleckman, P, Shimizu, N, Kudoh, J, Irvine, AD, Amagai, M, McLean, WH, A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming., Nature Genetics, 41, (5), 2009, p602 - 608
O'Regan, G.M., Irvine, A.D., Yao, N., O'Marcaigh, A., Sheridan-Pereira, M., Phelan, E., McDermott, M.B., (...), Watson, R., Mediastinal and neck kaposiform hemangioendothelioma , Pediatric Dermatology, 26, (3), 2009, p331-337
Sun M, Li N, Dong W, Chen Z, Liu Q, Xu Y, He G, Shi Y, Li X, Hao J, Luo Y, Shang D, Lv D, Ma F, Zhang D, Hua R, Lu C, Wen Y, Cao L, Irvine AD, McLean WH, Dong Q, Wang MR, Yu J, He L, Lo WH, Zhang X, Copy-number mutations on chromosome 17q24.2-q24.3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasia., American journal of human genetics, 84, (6), 2009, p807-13
Irvine, AD., Towards a unified classification of the ectodermal dysplasias: Opportunities outweigh challenges. , American Journal Of Medical Genetics Part A, 149A, (9), 2009, p1970-1972
Genetics in, editor(s)Beiber T, Leung D , Atopic Dermatitis, London, Informa Healthcare, 2009, [Weidinger S, Rodriguez E, Irvine AD]
Wen, Y, Liu, Y, Xu, Y, Zhao, Y, Hua, R, Wang, K, Sun, M, Li, Y, Yang, S, Zhang, XJ, Kruse, R, Cichon, S, Betz, RC, Nöthen, MM, van Steensel, MA, van Geel, M, Steijlen, PM, Hohl, D, Huber, M, Dunnill, GS, Kennedy, C, Messenger, A, Munro, CS, Terrinoni, A, Hovnanian, A, Bodemer, C, de Prost, Y, Paller, AS, Irvine, AD, Sinclair, R, Green, J, Shang, D, Liu, Q, Luo, Y, Jiang, L, Chen, HD, Lo, WH, McLean, WH, He, CD, Zhang, X, Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis., Nature genetics, 41, (2), 2009, p228 - 233
Sun M, Li N, Dong W, Chen Z, LiuQ, XuY, He G, Shi Y, Li X, Hao J, Luo Y, Shang D, Lv D, Ma F, Zhang D, Hua R, Lu C, Wen Y, Cao L, Irvine AD, McLean WHI, Dong Q, Wang M-R, Yu J, He L, Lo WHY, Zhang X, Copy number mutations on chromosome 17q24.2-q24.3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasia, American Journal of Human Genetics, 84, (6), 2009, p807-813.
O'Regan GM, Irvine AD, Yao N, O'Marcaigh A, Sheridan-Pereira M, Phelan E, McDermott MB, Twomey A, Russell J, Watson R, Mediastinal and neck kaposiform hemangioendothelioma: report of three cases., Pediatric dermatology, 26, (3), 2009, p331-7
Wen, Y., Liu, Y., Xu, Y., Zhao, Y., Hua, R., Wang, K., Sun, M., Li, Y., Yang, S., Zhang, X.-J., Kruse, R., Cichon, S., Betz, R.C., Nöthen, M.M., Van Steensel, M.A.M., Van Geel, M., Steijlen, P.M., Hohl, D., Huber, M., Dunnill, G.S., Kennedy, C., Messenger, A., Munro, C.S., Terrinoni, A., Hovnanian, A., Bodemer, C., De Prost, Y., Paller, A.S., Irvine, A.D., Sinclair, R., Green, J., Shang, D., Liu, Q., Luo, Y., Jiang, L., Chen, H.-D., Lo, W.H.-Y., McLean, W.H.I., He, C.-D., Zheng, X., Erratum: Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis (Nature Genetics (2009) 41 (228-233)), Nature Genetics, 41, (6), 2009
Rodríguez E, Baurecht H, Herberich E, Wagenpfeil S, Brown SJ, Cordell HJ, Irvine AD, Weidinger S, Meta analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease, Journal of Allergy and Clinical Immunology, 123, (6), 2009, p1361-1370.e7
Irvine AD, Towards a unified classification of the ectodermal dysplasias: opportunities outweigh challenges., American journal of medical genetics. Part A, 149A, (9), 2009, p1970-2
McLean, W.H.I., Palmer, C.N.A., Henderson, J., Kabesch, M., Weidinger, S., Irvine, A.D., Filaggrin variants confer susceptibility to asthma , Journal of Allergy and Clinical Immunology, 121, (5), 2008, p1294-1295
Genomics of the Epidermis and Appendages, Skin Pigmentation, And Skin Cancer in, editor(s)Kumar D, Weatherall D , Genomics and Clinical Medicine, New York , Oxford University Press, 2008, pp507-529 , [Healy E, Irvine AD, Lear JT, Munro CS]
Grainne M. O'Regan, Aileen Sandilands, WH Irwin McLean and Alan D. Irvine , Current Perspectives Series: Filaggrin in Atopic Dermatitis, Journal of Allergy and Clinical Immunology, 122, (4), 2008, p689-693
Henderson, J, Northstone, K, Lee, SP, Liao, H, Zhao, Y, Pembrey, M, Mukhopadhyay, S, Smith, GD, Palmer, CN, McLean, WH, Irvine, AD, The burden of disease associated with filaggrin mutations: a population-based, longitudinal birth cohort study., The Journal of allergy and clinical immunology, 121, (4), 2008, p872-877
Kezic S, Kemperman PMJH, Koster E, de Jongh C, Thio BH, Campbell LE, Irvine AD, McLean WHI, Puppels GJ, Caspers PJ, Loss-of-function mutations in the filaggrin gene lead to reduced levels of natural moisturizing factor in the stratum corneum, Journal of Investigative Dermatology, 128, (8), 2008, p2117-2119
Field S, Irvine AD, Kirby B., The treatment of viral warts with topical cidofovir 1%: our experience of seven paediatric patients., British Journal of Dermatology, 160, (1), 2008, p223-224
Weidinger, S, Baurecht, H, Wagenpfeil, S, Henderson, J, Novak, N, Sandilands, A, Chen, H, Rodriguez, E, O'Regan, GM, Watson, R, Liao, H, Zhao, Y, Barker, JN, Allen, M, Reynolds, N, Meggitt, S, Northstone, K, Smith, GD, Strobl, C, Stahl, C, Kneib, T, Klopp, N, Bieber, T, Behrendt, H, Palmer, CN, Wichmann, HE, Ring, J, Illig, T, McLean, WH, Irvine, AD, Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk., The Journal of allergy and clinical immunology, 122, (3), 2008, p560-568.e4
Cox, D, O' Regan, G, Collins, S, Byrne, A, Irvine, A, Watson, R, Juvenile localised scleroderma: a retrospective review of response to systemic treatment., Irish Journal of Medical Science, 177, (4), 2008, p343-346
Weidinger, S, O'Sullivan, M, Illig, T, Baurecht, H, Depner, M, Rodriguez, E, Ruether, A, Klopp, N, Vogelberg, C, Weiland, SK, McLean, WH, von Mutius, E, Irvine, AD, Kabesch, M, Filaggrin mutations, atopic eczema, hay fever, and asthma in children., The Journal of allergy and clinical immunology, 121, (5), 2008, p1203-1209.e1
Brown, SJ, Irvine, AD, Atopic eczema and the filaggrin story., Seminars in cutaneous medicine and surgery, 27, (2), 2008, p128-137
O'Regan, GM, Sandilands, A, McLean, WH, Irvine, AD, Filaggrin in atopic dermatitis., The Journal of Allergy and Clinical Immunology, 122, (4), 2008, p689-693
Cusack, C, Fitzgerald, D, Clayton, TM, Irvine, AD, Successful treatment of florid cutaneous warts with intravenous cidofovir in an 11-year-old girl., Pediatric Dermatology, 25, (3), 2008, p387-389
O'Regan, GM, Irvine, AD, The role of filaggrin loss-of-function mutations in atopic dermatitis., Current opinion in allergy and clinical immunology, 8, (5), 2008
Sandilands A, Terron-Kwiatkowski A, Hull PR, O'Regan GM, Clayton TH, Watson RM, Carrick T, Evans AT, Liao H, Zhao Y, Campbell LE, Schmuth M, Gruber R, Janecke AR, Elias PM, van Steensel MAM, Nagtzaam I, van Geel M, Steijlen PM, Munro CS, Bradley DG, Palmer CNA, Smith FJD, McLean WHI, Irvine AD, Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema , Nature Genetics, 39, (5), 2007, p650 - 654
Zhao, Y, Terron-Kwiatkowski, A, Liao, H, Lee, SP, Allen, MH, Hull, PR, Campbell, LE, Trembath, RC, Capon, F, Griffiths, CE, Burden, D, McManus, R, Hughes, R, Kirby, B, Rogers, SF, Fitzgerald, O, Kane, D, Barker, JN, Palmer, CN, Irvine, AD, McLean, WH, Filaggrin null alleles are not associated with psoriasis., The Journal of investigative dermatology, 127, (8), 2007, p1878-1882
Dermatology in, editor(s)Strobel S, Smith P, El Habbal MH, Spitz, L, , The Great Ormond Street Colour Handbook of Paediatric Medicine and Surgery, London, Manson Publishing, 2007, pp131-159 , [Irvine AD, Lomas D, Atherton DJ, Harper JI ]
O'Connell S, O'Regan GM, Bolger T, Hoffman HM, Cant A, Irvine AD, Watson R, Response to Il-1-Receptor Antagonist in a child with Familial Cold Autoinflammatory Syndrome, Pediatric Dermatology, 24, (1), 2007, p85 - 89
Liao, H., Sayers, J.M., Wilson, N.J., Irvine, A.D., Mellerio, J.E., Baselga, E., Bayliss, S.J., (...), Smith, F.J.D., A spectrum of mutations in keratins K6a, K16 and K17 causing pachyonychia congenita , Journal of Dermatological Science, 48, (3), 2007, p199-205
Irvine AD, Fleshing out filaggrin phenotypes, Journal of Investigative Dermatology, 127, (3), 2007, p504 - 507
Clayton, T.H., Barry, J., Fitzgerald, D., Watson, R., Irvine, A.D., Clarithromycin suspension-associated toxic epidermal necrolysis in a 2-year-old girl [5] , Clinical and Experimental Dermatology , 32, (6), 2007, p755-756
Irvine AD, Fleshing out filaggrin phenotypes., The Journal of investigative dermatology, 127, (3), 2007, p504-7
Porokeratoses in, Wolff K, Katz S, Goldsmith L, Gilchrest B , Paller A, Leffell D , Fitzpatrick's Dermatology in General Medicine, New York , McGraw Hill, 2007, [O'Regan GM, Irvine AD]
Sandilands, A, Smith, FJ, Irvine, AD, McLean, WH, Filaggrin's fuller figure: a glimpse into the genetic architecture of atopic dermatitis., The Journal of Investigative Dermatology, 127, (6), 2007, p1282-1284
O'Regan, GM, Zurada, J, Martinez-Mir, A, Christiano, AM, Irvine, AD, A recurrent splice-site mutation in the human hairless gene underlies congenital atrichia in Irish families., The British Journal of Dermatology, 156, (4), 2007, p744-747
Disorders of cornification in, Esterly N, Eichenfield L, Frieden I , Neonatal Dermatology, Philadelphia, Elsevier, 2007, pp285-310 , [Irvine AD, Paller AS ]
McLean, WH, Irvine, AD, Disorders of keratinisation: from rare to common genetic diseases of skin and other epithelial tissues., The Ulster Medical Journal, 76, (2), 2007, p72-82
Baurecht, H, Irvine, AD, Novak, N, Illig, T, Bühler, B, Ring, J, Wagenpfeil, S, Weidinger, S, Toward a major risk factor for atopic eczema: meta-analysis of filaggrin polymorphism data., The Journal of allergy and clinical immunology, 120, (6), 2007, p1406-1412
O'Regan, GM, Watson, R, Orr, D, O'Donovan, D, Russell, J, Phelan, E, Ryan, M, Brosnahan, O, Irvine, A, Management of vascular birthmarks: review of a multidisciplinary clinic., Irish Medical Journal, 100, (4), 2007
Collins SM, Dominguez M, Ilmarinen T, C Costigan C, Irvine AD, Dermatological manifestations of autoimmune polyendocrinopathy - candidiasis - ectodermal dystrophy (APECED) syndrome, British Journal of Dermatology, 154, (6), 2006, p1088 - 1093
Smith, F.J.D., Irvine, A.D., Terron-Kwiatkowski, A., Sandilands, A., Campbell, L.E., Zhao, Y., Liao, H., Evans, A.T., Goudie, D.R., Lewis-Jones, S., Arseculeratne, G., Munro, C.S., Sergeant, A., O'Regan, G., Bale, S.J., Compton, J.G., Digiovanna, J.J., Presland, R.B., Fleckman, P., McLean, W.H.I., Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris, Nature Genetics, 38, (3), 2006, p337-342
McLean, WHI, Wood, P, Irvine, AD, von der Werth, J, Mapping of two genetic loci for autosomal dominant hidradenitis suppurativa, Experimental Dermatology, 15, (6), 2006, p479-479
Dominguez M, Crushell E, Ilmarinen T, McGovern E, Collins S, Chang B, Fleming P, Irvine AD, Brosnahan D, Ulmanen I, Murphy N, Costigan C, Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED) in the Irish Population, Journal of Pediatric Endocrinology and Metabolism, 19, (11), 2006, p1343 - 1352
Palmer CNA, Irvine AD, Terron-Kwiatkowski A, Zhao Y, Liao H, Lee SP, Goudie DR, Sandilands A, Campbell LE, Smith FJD, O'Regan GM, Watson RM, Cecil JE, Bale SJ, Compton JG, DiGiovanna JJ, Fleckman P, Lewis-Jones S, Arseculeratne G, Sergeant A, Munro CS, El Houate B, McElreavey K, Halkjaer LB, Bisgaard H, Mukhopadhyay S, McLean WHI, Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis, Nature Genetics, 38, (4), 2006, p441 - 446
Irvine AD and McLean WHI, Breaking the (un) sound barrier: filaggrin is a major gene for atopic dermatitis, Journal of Investigative Dermatology, 126, (6), 2006, p1200 - 1202
Genetics of Hidradenitis Suppurativa in, editor(s)Jemec GBE, Revuz J and Leyden JJ , Hirdadenitis Suppurativa, Berlin & Heidelberg , Springer, 2006, pp70-85 , [von der Werth J, Wood P, Irvine AD, McLean WHI ]
Sandilands A, O'Regan GM, Smith FJD, McLean WHI, Irvine AD, Prevalent and Rare Mutations in the Gene Encoding Filaggrin Cause Ichthyosis Vulgaris and Predispose Individuals to Atopic Dermatitis, Journal of Investigative Dermatology, 126, 2006, p1770 - 1775
Madasseri A, McDermott MB, Irvine AD, Lipoatrophic panniculitis of the ankles, Clinical and Experimental Dermatology, 31, (2), 2006, p303 - 530
Weidinger S, Illig T, Baurecht H, Irvine AD, Rodriguez E, Diaz-Lacava A, Klopp N, Wagenpfeil S, Zhao Y, Liao H, Lee SP, Palmer CNA, Jenneck C, Maintz L, Hagemann T, Behrendt H, Ring J, Nothen MM, McLean WHI, Novak N, Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations, Journal of Allergy and Clinical Immunology, 118, (1), 2006, p214 - 219
O'Regan, G.M., Canny, G., Irvine, A.D., 'Peeling paint' dermatitis as a presenting sign of cystic fibrosis, Journal of Cystic Fibrosis, 5, (4), 2006, p257-259
O'Regan GM, Canny G, Irvine AD, Peeling paint' dermatitis as a presenting sign of cystic fibrosis, Journal of Cystic Fibrosis, 5, (4), 2006, p257 - 259
Irvine AD, McLean WH, Breaking the (un)sound barrier: filaggrin is a major gene for atopic dermatitis., The Journal of investigative dermatology, 126, (6), 2006, p1200-2
Smith FJD, Irvine AD, Terron-Kwiatkowski A, Sandilands A, Campbell LE, Zhao Y, Liao L, Evans AT, Goudie DR, Lewis-Jones S, Arseculeratne G, Munro CS, Sergeant A, O'Regan G, Bale SJ, Compton JG, DiGiovanna JJ, Presland RB, Fleckman P, Irwin McLean WHI, Loss-of-function mutations in the filaggrin gene cause ichthyosis vulgaris, Nature Genetics, 38, (3), 2006, p337 - 342
O'Regan, G.M., Irvine, A.D., Disorders due to mutations in keratin genes , Giornale Italiano di Dermatologia e Venereologia, 140, (6), 2005, p667-676
Ectodermal dysplasias in, editor(s)Harper JI, Oranje OP, Prose N , Pediatric Dermatology , Oxford , Blackwell Scientific, 2005, pp1412-1466 , [Irvine AD]
Irvine, A.D., Inherited defects in keratins, Clinics in Dermatology, 23, (1), 2005, p6-14
Irvine AD, Inherited defects in keratins, Clinics in Dermatology, 23, (1), 2005, p6-14
Tobin AM, Cotter M, Irvine AD, Kirby B, Successful treatment of a refractory verruca in a child with acute lymphoblastic leukaemia with topical cidofovir, British Journal of Dermatology, 152, (2), 2005, p386 - 388
McLean, W.H.I., Irvine, A.D., Hamill, K.J., Whittock, N.V., Coleman-Campbell, C.M., Mellerio, J.E., Ashton, G.S., Dopping-Hepenstal, P.J.H., Eady, R.A.J., Jamil, T., Phillips, R.J., Ghulam Shabbir, S., Haroon, T.S., Khurshid, K., Moore, J.E., Page, B., Darling, J., Atherton, D.J., van Steensel, M.A.M., Munro, C.S., Smith, F.J.D., McGrath, J.A., Erratum: An unusual N-terminal deletion of the laminin "3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome (Human Molecular Genetics (2003) vol. 12 (2395-2409)), Human Molecular Genetics, 13, (3), 2004
Terron-Kwiatkowski A, Terrinoni A, Didona B, Melino G, Atherton D, Irvine AD, Mclean WHI, Atypical Epidermolytic Palmoplantar Keratoderma Presentation Associated With A Mutation In The Keratin 1 Gene, British Journal of Dermatology, 150, (6), 2004, p1096 - 1103
Veugelers M, Wilkes D, Burton K, McDermott D, Song Y, Vaughan CJ, La Perle K, Goldstein G, Kligfield P, O'Hagan A, Bennett K, Meyer BJ, Legius E, Kartunnen M, Lavyne M, Neau J-P, Richter G, Kirali K, Stapleton K, Morelli P, Norio R, Takanashi Y, Farnsworth A, Bamforth J-S, Eitelberger F, Manfroi W, Ko GTC, Powers J, Mochizuki Y, Imai T, Driscoll DA, Goldmuntz E, Edelberg J, Eccles D, Irvine AD, McKnight GS, Basson CT, Comparative PRKAR1 a Genotype-Phenotype Analyses in Humans with Carney complex and prkar1 a Haploinsufficient Mice, Proceedings of The National Academy of Sciences, 101, (39), 2004, p14222 - 14227
Veugelers, M., Wilkes, D., Burton, K., McDermott, D.A., Song, Y., Goldstein, M.M., La Perle, K., (...), Basson, C.T., Erratum: Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice (Proceedings of the National Academy of Sciences of the United States of America (September 28, 2004) 101:39 (14222-14227)), 2004, - 15546
Veugelers, M., Wilkes, D., Burton, K., McDermott, D.A., Song, Y., Goldstein, M.M., La Perle, K., Vaughan, C.J., O'Hagan, A., Bennett, K.R., Meyer, B.J., Legius, E., Karttunen, M., Norio, R., Kaariainen, H., Lavyne, M., Neau, J.-P., Richter, G., Kirali, K., Farnsworth, A., Stapleton, K., Morelli, P., Takanashi, Y., Bamforth, J.-S., Eitelberger, F., Noszian, I., Manfroi, W., Powers, J., Mochizuki, Y., Imai, T., Ko, G.T.C., Driscoll, D.A., Goldmuntz, E., Edelberg, J.M., Collins, A., Eccles, D., Irvine, A.D., McKnight, G.S., Basson, C.T., Erratum: Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice (Proceedings of the National Academy of Sciences of the United States of America (September 28, 2004) 101:39 (14222-14227)), Proceedings of the National Academy of Sciences of the United States of America, 101, (43), 2004
McLean, W.H.I., Irvine, A.D., Hamill, K.J., Whittock, N.V., Coleman-Campbell, C.M., Mellerio, J.E., Ashton, G.S., (...), McGrath, J.A., Erratum: An unusual N-terminal deletion of the laminin α3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome, 2004, - 2395-2409
O'Hagan, AH, Irvine AD, Sands A, O'Donaghue D, Casey F, Bingham EA, Miliary Neonatal Hemangiomatosis with Fulminant Heart Failure and Cardiac Septal Hypertrophy in Two Infants, Pediatric Dermatology, 21, (4), 2004, p469 - 472
Skin: Hereditary Disorders in, Cooper DN , Nature Encyclopaedia of the Human Genome, London., John Wiley and Sons Ltd, 2003, pp314-325 , [Corden LD, McLean WHI and Irvine AD]
McMullen EA, McCarron P, Irvine AD, Dolan OM, Allen GE, Association between long-term acitretin therapy and osteoporosis: no evidence of increased risk, Clinical and Experimental Dermatology, 28, (3), 2003, p307 - 309
Paller AS, Irvine AD, Russi DC, Raised limb bands developing in infancy, British Journal of Dermatology, 149, (2), 2003, p436 - 437
Irvine AD and McLean WHI, The Molecular Genetics of The Genodermatoses: Progress To Date And Future Directions, British Journal of Dermatology, 148, (1), 2003, p1-13
McLean WH, Irvine AD, Hamill KJ, Whittock NV, Coleman-Campbell CM, Mellerio JE, Ashton GS, Dopping-Hepenstal PJ, Eady RA, Jamil T, Phillips R, Shabbir SG, Haroon TS, Khurshid K, Moore JE, Page B, Darling J, Atherton DJ, Van Steensel MA, Munro CS, Smith FJ, McGrath JA, Phillips RJ, An unusual N-terminal deletion of the laminin alpha3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome., Human molecular genetics, 12, (18), 2003, p2395-409
Epithelial corneal dystrophies. in, editor(s)Wang M, Flatten N , Cornea: Dystrophies and Degenerations: A Molecular Genetics Approach, San Francisco, Oxford University Press Inc, 2003, pp19-45 , [Irvine AD, Wang M, McLean WHI ]
Irvine, A.D., McLean, W.H.I., The molecular genetics of the genodermatoses: Progress to date and future directions, British Journal of Dermatology, 148, (1), 2003, p1-13
Hair Loss: Genetics. in, editor(s)Cooper DN , Nature Encyclopaedia of the Human Genome, London , John Wiley and Sons Ltd, 2003, pp153-159 , [Irvine AD]
Wang LL, Gannavarapu A, Clericuzio CL, Erickson RP, Irvine AD, Plon SE, Absence of RECQL4 mutations in poikiloderma with neutropenia in Navajo and non-Navajo patients, American Journal of Medical Genetics A, 118, (3), 2003, p299 - 301
McLean WHI, Irvine AD, Hamill KJ, Whittock NV, Coleman CM, Mellerio JE, Ashton GS, Dopping-Hepenstal PJH, Eady RAJ, Jamil T, Phillips RJ, Shabbir SG, Haroon TS, Khurshid K, Moore JE, Page B, Darling J, Atherton DJ, Munro CS, Smith FJD, McGrath JA, An unusual N-terminal deletion of the laminin α3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome, Human Molecular Genetics, 12, (18), 2003, p2395 - 2409
Irvine, A.D., Paller, A.S., Molecular genetics of the inherited disorders of cornification: an update., Advances in dermatology, 18, 2002, p111-149
Bitoun E, Chavanas S, Irvine AD, Lonie L, Bodemer C, Paradisi M, Hamel-Teillac, Ansai S, Mitsuhashi Y, Taïeb A, de Prost Y, Zambruna G, Harper JI, Hovnanian A, Netherton Syndrome: Disease expression and Spectrum of SPINK5 Mutations in 21 families, Journal of Investigative Dermatology, 118, (2), 2002, p352 - 361
Irvine, A.D., Paller, A.S., Inherited disorders of keratinization, Current Problems in Dermatology, 14, (3), 2002, p71-115
Irvine AD, Paller AS, The Molecular Genetics of the Inherited Disorders of Keratinization: An update, Advances in Dermatology, 18, 2002, p111-49
Terron-Kwiatkowski A, Paller AS, Compton J, Atherton DJ, McLean WH, Irvine AD, Two cases of primarily palmoplantar keratoderma associated with novel mutations in keratin 1., The Journal of investigative dermatology, 119, (4), 2002, p966-71
Irvine AD, Paller AS, Inherited disorders of Keratinization, Current Problems in Dermatology, 14, (3), 2002, p71-116
Hay-Wells syndrome. in, editor(s)Gruson ES , NORD Guide to Rare Disorders, Philadelphia , Lippincott, Williams & Wilkins, 2002, pp116-117 , [Irvine AD, McGrath JA]
Irvine AD, Sun P, Kos L, Wang X, Paller AS, A colorimetric bead-binding assay for detection of intermolecular interactions, Experimental Dermatology, 11, (5), 2002, p465 - 471
Terron-Kwiatkowski A, Paller AS, Compton J, Atherton DJ, McLean WHI, Irvine AD, Two cases of primarily palmoplantar keratoderma associated with novel mutations in keratin 1, Journal of Investigative Dermatology, 119, (4), 2002, p966 - 971
Irvine AD, Coleman CM,. Moore JE, Swensson O, Morgan SJ, McCarthy JH, Smith FJD, Black GCM, McLean WHI, A novel mutation in KRT12 associated with Meesmann's Epithelial Corneal Dystrophy, British Journal of Ophthalmology, 86, (7), 2002, p729 - 732
Bitoun E, Chavanas S, Irvine AD, Lonie L, Bodemer C, Paradisi M, Hamel-Teillac D, Ansai S, Mitsuhashi Y, Taïeb A, de Prost Y, Zambruno G, Harper JI, Hovnanian A, Netherton syndrome: disease expression and spectrum of SPINK5 mutations in 21 families., The Journal of investigative dermatology, 118, (2), 2002, p352-61
McGrath JA, Duijf P, Doetsch V, Irvine AD, de Waal R, Vanmolkot K, Wessagowit VA, Kelly K, Atherton DJ, Griffiths WAD, Orlow SJ, van Haeringen A, Ausems M, Yang A, McKeon F, Bamshad MA, Brunner HG, Hamel BCJ, van Bokhoven H, Hay-Wells syndrome is caused by missense mutations in the SAM domain of p63, Human Molecular Genetics, 10, (3), 2001, p221 - 229
McGrath JA, Duijf PH, Doetsch V, Irvine AD, de Waal R, Vanmolkot KR, Wessagowit V, Kelly A, Atherton DJ, Griffiths WA, Orlow SJ, van Haeringen A, Ausems MG, Yang A, McKeon F, Bamshad MA, Brunner HG, Hamel BC, van Bokhoven H, Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63., Human molecular genetics, 10, (3), 2001, p221-9
Irvine AD, Rugg EL, Lane EB, Hoare S, Peret C, Hughes AE, Heagerty AH, Molecular confirmation of the unique phenotype of epidermolysis bullosa simplex with mottled pigmentation, British Journal of Dermatology, 144, (1), 2001, p40 - 46
Irvine, A.D., Christiano, A.M., Hair on a gene string: Recent advances in understanding the molecular genetics of hair loss, Clinical and Experimental Dermatology, 26, (1), 2001, p59-71
Irvine AD, Christiano AM, Hair on a gene string: recent advances in understanding the molecular genetics of hair loss, Clinical and Experimental Dermatology, 26, (1), 2001, p59-714
Moore JE, Dua HS, Page AB, Irvine AD, Archer DB, Ocular surface reconstruction in LOGIC syndrome by amniotic membrane transplantation, Cornea, 20, (1), 2001, p753 - 756
O'Hagan AH, Irvine AD, Brennan T, Walsh MY, Bingham EA, Fibrous histiocytoma in a nine week old male infant, European Journal of Pediatric Dermatology, 11, (1), 2001, p13 - 18
Irvine AD, Smith FJD, Shum KW, Williams HC, McLean WHI, A novel mutation in the 2B domain of keratin 2e causing Ichthyosis Bullosa of Siemens, Clinical and Experimental Dermatology, 25, (8), 2000, p648 - 652
Chavanas S, Bodemer C, Rochat A, Hamel-Teillac D, Ali M, Irvine AD, Bonafé J-L, Taïeb A, Barrandon Y, Harper JI, de Prost, Y, Hovnanian A, Mutations in SPINK5 encoding a novel serine protease inhibitor cause Netherton Syndrome, Nature Genetics, 25, (2), 2000, p141 - 142
Smith FJD, McKenna KE, Irvine AD, Bingham EA, Coleman CM, Uitto J, McLean WHI, A mutation detection strategy for the human keratin 6A gene and novel missense mutations in two cases of pachyonychia congenita type 1, Experimental Dermatology, 8, (2), 1999, p109 - 111
Korge BP, Hamm H, Jury CS, Traupe H, Irvine AD, Healey E, Birch-Machin, M, Rees JL, Messenger AG, Holmes SC, Parry DAD, Munro CS, Identification of novel mutations in basic hair keratins hHb1 and hHb6 in monilethrix: implications for protein structure and clinical phenotype, Journal of Investigative Dermatology, 113, (4), 1999, p607 - 612
Irvine, A.D., McLean, W.H.I., Human keratin diseases: The increasing spectrum of disease and subtlety of the phenotype-genotype correlation, British Journal of Dermatology, 140, (5), 1999, p815-828
Korge BP, Hamm H, Jury CS, Traupe H, Irvine AD, Healy E, Birch-MacHin M, Rees JL, Messenger AG, Holmes SC, Parry DA, Munro CS, Identification of novel mutations in basic hair keratins hHb1 and hHb6 in monilethrix: implications for protein structure and clinical phenotype., The Journal of investigative dermatology, 113, (4), 1999, p607-12
Irvine AD and McLean WHI, Human keratin diseases: the increasing spectrum of disease and the subtlety of genotype-phenotype correlation, British Journal of Dermatology, 140, (5), 1999, p815-828
Ahmad W, Irvine AD, Lam H, Buckley C, Bingham EA, Panteleyev AA, Ahmad A, McGrath JA, Christiano AM, A missense mutation in the zinc-finger domain of the human hairless gene underlies congenital atrichia in a family of Irish travellers, American Journal of Human Genetics, 63, (4), 1998, p984 - 991
Irvine AD, Bruce IN, Walsh MY, Bingham EA, Antineutrophil cytoplasmic antibodies in leukocytoclastic vasculitis, Archives of Dermatology, 134, (2), 1998, p239 - 240
Ahmad W, Irvine AD, Lam H, Buckley C, Bingham EA, Panteleyev AA, Ahmad M, McGrath JA, Christiano AM, A missense mutation in the zinc-finger domain of the human hairless gene underlies congenital atrichia in a family of Irish travellers., American journal of human genetics, 63, (4), 1998, p984-91
Casey M, Mah C, Merliss AD, Kirschner LS, Taymans SE, Denio AE, Korf B, Irvine AD, Hughes AE, Carney JA, Stratakis CA, Basson CT, Identification of a novel genetic locus for familial cardiac myxoma and Carney complex, Circulation, 98, (23), 1998, p2560 - 2566
Covello SP, Irvine AD, McKenna KE, Munro CS, Nevin NC, Smith FJD, Uitto J, McLean WHI, Mutations in keratin K9 in kindreds with epidermolytic palmoplantar keratoderma and epidemiology in Northern Ireland, Journal of Investigative Dermatology, 111, 1998, p1207 - 1209
O'Hagan A, Irvine AD, Allen GE, Mefenamic acid induced pseudoporphyria, British Journal of Dermatology, 139, (6), 1998, p1131 - 1132
O'Hagan A, Irvine AD, Walsh M, Allen GE, Pyodermatitis-pyostomatitis vegetans: evidence of an entirely mucocutaneous variant, British Journal of Dermatology, 138, (3), 1998, p552 - 555
O'Hagan, A.H., Irvine, A.D., Allen, G.E., Walsh, M., Pseudoporphyria induced by mefenamic acid [16], British Journal of Dermatology, 139, (6), 1998, p1131-1132
Sais, G., Vidaller, A., Jucgla, A., Gallardo, F., Peyri, J., Irvine, A.D., Bruce, I.N., Antineutrophil cytoplasmic antibodies in leukocytoclastic vasculitis [1] (multiple letters), Archives of Dermatology, 134, (2), 1998, p239-240
Casey M, Mah C, Merliss AD, Kirschner LS, Taymans SE, Denio AE, Korf B, Irvine AD, Hughes A, Carney JA, Stratakis CA, Basson CT, Identification of a novel genetic locus for familial cardiac myxomas and Carney complex., Circulation, 98, (23), 1998, p2560-6
Irvine AD, Armstrong DKB, Bingham EA, Hadden DR, Nevin NC, Hughes AE, Evidence for a second genetic locus in Carney complex, British Journal of Dermatology, 138, 1998, p572 - 576
Irvine AD, McKenna KE, Jenkinson H, Hughes AE, A mutation in the V1 Domain of keratin 5 causes Epidermolysis Bullosa Simplex with Mottled Pigmentation, Journal of Investigative Dermatology, 108, (5), 1997, p809 - 810
Irvine AD, Bruce IN, Walsh MY, Bingham EA, Microscopic polyangiitis. Delineation of a cutaneous-limited variant associated with antimyeloperoxidase autoantibody., Archives of Dermatology, 133, (4), 1997, p474 - 477
Irvine AD, Corden LD, Swensson O, Swensson B, Moore JE, Frazer DG, Smith FJD, Knowlton RG, Christophers E, Rochels R, Uitto J, McLean WHI., Mutations in cornea-specific keratins K3 or K12 cause Meesmann's corneal dystrophy, Nature Genetics, 16, 1997, p184 - 187
Loughrey MB, Irvine AD, Girdwood RWA, McMillan CM, Cutaneous larva migrans: the case for routine oral treatment, British Journal of Dermatology, 137, (1), 1997, p155 - 158
Armstrong DKB, Irvine AD, Handley JM, Walsh MY, Hadden DR, Bingham EA, Carney complex: report of a new kindred with predominantly cutaneous manifestations, British Journal of Dermatology, 136, (4), 1997, p578 - 582
Irvine AD, McKenna KE, Bingham A, Nevin NC, Hughes AE, A novel mutation in the helix termination peptide of keratin 5 causing epidermolysis bullosa simplex Dowling-Meara., The Journal of investigative dermatology, 109, (6), 1997, p815-6
Irvine AD, McKenna KE, Bingham EA, Nevin NC, Hughes AE, A novel mutation in the helix termination peptide of keratin 5 causing Epidermolysis bullosa simplex Dowling-Meara, Journal of Investigative Dermatology, 109, 1997, p815 - 816
Irvine AD, Dolan OM, Hadden DR, Stewart FJ, Bingham EA, Nevin NC, An autosomal dominant syndrome of acromegaloid facial appearance and generalised hypertrichosis terminalis., Journal of medical genetics, 33, (11), 1996, p972-4
Irvine AD, Stewart FJ, Bingham EA, Nevin NC, Boston VE, Focal dermal hypoplasia (Goltz Syndrome) associated with intestinal malrotation and mediastinal dextroposition., American Journal of Medical Genetics, 62, (3), 1996, p213-215
Irvine AD, Sweeney LE, Corbett JR, Lymphangioma circumscriptum associated with paravesical cystic retroperitoneal lymphangioma, British Journal of Dermatology, 134, (6), 1996, p1135 - 1137
Irvine AD, Stewart FJ, Bingham EA, Nevin NC, Boston VE, Focal dermal hypoplasia (Goltz Syndrome) associated with intestinal malrotation and mediastinal dextroposition, American Journal of Medical Genetics, 62, (3), 1996, p213 - 215
Irvine AD, Dolan OM, Hadden DR, Stewart FJ, Bingham EA, Nevin NC, An autosomal dominant syndrome of acromegaloid facial appearance and generalised hypertrichosis terminalis, Journal of Medical Genetics, 33, (11), 1996, p972 - 974
Irvine AD, Kenny B, Walsh MY, Burrows D, Primary cutaneous adenoid cystic carcinoma, Clinical and Experimental Dermatology, 21, 1996, p249 - 250
Irvine, A.D., Bruce, I.N., Walsh, M., Burrows, D., Handley, J., Dermatological presentation of disease associated with antineutrophil cytoplasmic antibodies: A report of two contrasting cases and a review of the literature, British Journal of Dermatology, 134, (5), 1996, p924-928
Irvine AD, Bruce IN, Walsh M, Burrows D, Handley J, Dermatological presentation of ANCA associated disease: a report of two contrasting cases and review of the literature, British Journal of Dermatology, 134, (5), 1996, p924 - 928
Armstrong DKB, Irvine A, Walsh MY, Mayne EE, Burrows D, Multiple dermatofibromas in a patient with HIV infection, Clinical and Experimental Dermatology, 20, (6), 1995, p474 - 476
Dolan OM, Burrows D, Irvine A, Walsh M, The value of a baseline liver biopsy prior to methotrexate therapy, British Journal of Dermatology, 131, (6), 1994, p891 - 894
Sakas, D.E., O"Connor, G., Singh, J., Dias, L., Eljamel, M.S., Mathew, B., Clements, B., Irvine, A., Gray, W.J., Byrnes, D.P., Bailey, I.C., Pathirana, N., Refsum, S., Bell, K.E., McKinstry, C.S., Callaghan, N., Crowley, M., Goggin, T., MacDermott, N., O"Driscoll, K.J., Neary, D., Pearson, N.A., Snowden, J.S., Brown, S., Vaughan, M., McMackin, D., Phillips, J., Burke, T., Murphy, S., Staunton, H., Cristea, R.L., Hourihane, M., Farrell, M.A., Morrison, P.J., Nevin, N.C., Collins, A.D., Gibson, M., Behan, W.M.H., Simpson, K.S., Cavanagh, H.M., Gow, J.W., Gillespie, J.S., Behan, P.O., Sklar, R.M., Brown, R.H., Gillian, A.M., O"Mahony, D., Breen, K.C., Hutchinson, J., Burke, T., Hutchinson, M., Droogan, A.G., Crockard, A.D., Hawkins, S.A., McNeill, T.A., Gutowski, N.J., Chirico, S., Pinkham, J.M., Smith, C., Akanu, D., Kaur, H., Strange, R.C., Halliwell, B., Murphy, R.P., Rogers, L., Weick, J., Estes, M., Elrington, G.M., Morris, C.S., Reffin, J.P., Tregear, S.J., Ripley, L.J., Rees, J.E., Irvine, A.D., O"Brien, D.P., Dias, P.S., Herity, N., Hawkins, S., McMenamin, J.B., Mirakhur, M., Allen, I.V., Bresnihan, B., Fitzsimmons, M., Sawhney, B., Patterson, V., Bailey, I.C., Byrnes, D., Watt, M., Lee, K.-C., Redmond, J.M.T., McKenna, M.J., Feingold, M., Ahmad, B.K., Watt, M., Cunningham, R.T., Winder, J., Lawson, J.A., Johnston, C.F., Buchanan, K.D., Dean, G., Elian, M., Gray, W.P., Ryder, D.Q., Buckley, T.F., Breathnach, K., Ooi, A., Farrell, M., Doherty, C., Hayes, F.J., Redmond, J.J.T., McKenna, M.M., Redmond, J.M.T., Farrell, M., Watt, M., Gibson, J.M., Patterson, V.H., Redmond, J.M.T., McKenna, M.J., Feingold, M., Ahmad, B.K., Moran, M., Burke, M., King, M.D., Moran, M., Burke, M., Hardiman, O., Reid, V., Dowd, J.O., Murphy, R., Rashad, E., Toland, J., Phillips, J.P., Staunton, H., Shu-Ming, P., Coughlin, A., Phillips, J.P., McCoy, D.M., Qureshi, A., Black, M.A., Grace, P.A., Bouchier-Hayes, D., Dwyer, R., Irish neurological association: Proceedings of 28th annual meeting, beaumont hospital, Dublin, 15th-16th may, 1992, Irish Journal of Medical Science, 162, (11), 1993, p474-484
Research Expertise
Description
Disease mechanisms and therapeutic development in inflammatory skin diseases, vascular anomalies and rare genetic skin diseaseRecognition
Representations
President, International Eczema Council
President, Irish Hospital Consultants Association
Grant Reviewer: The Wellcome Trust, Medical Research Council (UK), The Italian National Telethon, DEBRA International, British Skin Foundation
Reviewer: The Journal of Investigative Dermatology, The British Journal of Dermatology, Experimental Dermatology, European Journal of Human Genetics, Clinical and Experimental Dermatology, Journal of Allergy And Clinical Immunology, Allergy
Awards and Honours
Paul Gerson Unna Prize
Prix de La Foundation La Roche-Posay
Fulbright Scholarship
Geoffrey Dowling Fellowship, British Association of Dermatologists
Canadian Dermatology Association Prize, Best paper presented at the British Association of Dermatologists Annual Meeting
Young Investigator Fellowship, British Society for Investigative Dermatology
Hurwitz Lecture, Society For Pediatric Dermatology, Indianapolis, United States
Memberships
Association of Physicians of Great Britain & Ireland - Member
Royal College of Physicians of London - Fellow
The Royal College of Physicians of Ireland - Fellow
British Association of Dermatologists - Ordinary Member
Irish Association of Dermatologists - Member
Irish Society of Human Genetics - Member
British Society for Pediatric Dermatology - Member
Royal Academy of Medicine in Ireland - Member
European Society for Dermatological Research - Member
Society for Investigative Dermatology - Member
British Society for Investigative Dermatology - Member
The Dowling Club - Member