Publications and Further Research Outputs
Peer-Reviewed Publications
Bede P, Elamin M, Byrne S, McLaughlin RL, Kenna K, Vajda A, Pender N, Bradley DG, Hardiman O, Basal ganglia involvement in amyotrophic lateral sclerosis., Neurology, 81, (24), 2013, p2107-15
Bede P, Omer T, Finegan E, Chipika RH, Iyer PM, Doherty MA, Vajda A, Pender N, McLaughlin RL, Hutchinson S, Hardiman O., Connectivity-based characterisation of subcortical grey matter pathology in frontotemporal dementia and ALS: a multimodal neuroimaging study., Brain Imaging Behav, 2018, p1 - 19
Peter Bede, Parameswaran M. Iyer, Eoin Finegan, Taha Omer, Orla Hardiman, Virtual brain biopsies in amyotrophic lateral sclerosis: diagnostic classification based on in vivo pathological patterns, Neuroimage Clinical, 15, 2017, p653-658
Bede P, Bokde ALW, Byrne S, Elamin M, McLaughlin R, Kenna K, Fagan AJ, Pender N, Bradley DG, Hardiman O, A multiparametric MRI study of ALS stratified for the C9orf72 genotype, Neurology, 81, (4), 2013, p361 - 369
Peter Bede, Eoin Finegan., Revisiting the pathoanatomy of pseudobulbar affect: mechanisms beyond corticobulbar dysfunction., Amyotroph Lateral Scler Frontotemporal Degener. , 2, 2017, p1 - 3
Bede P, Iyer PM, Schuster C, Elamin M, Mclaughlin RL, Kenna K, Hardiman O., The selective anatomical vulnerability of ALS: 'disease-defining' and 'disease-defying' brain regions., Amyotroph Lateral Scler Frontotemporal Degener., 2016, p1-10
Schuster C, Elamin M, Hardiman O, Bede P., The segmental diffusivity profile of amyotrophic lateral sclerosis associated white matter degeneration., Eur J Neurol., 2016, p1-
Machts J, Loewe K, Kaufmann J, Jakubiczka S, Abdulla S, Petri S, Dengler R, Heinze HJ, Vielhaber S, Schoenfeld MA, Bede P., Basal ganglia pathology in ALS is associated with neuropsychological deficits., Neurology, 2015
Medical Mimics of Neurodegenerative Diseases in, editor(s)Hardiman, Doherty, Elamin, Bede , Neurodegenerative disorders: A clinical guide - Second Edition, Springer, 2015, [Rowland L, Bede P, Elamin M, Hardiman O]
Palliative care and end of life care in, editor(s)Hardiman, Doherty, Elamin, Bede , Neurodegenerative disorders: A clinical guide - Second Edition, Springer, 2015, [Oliver D, Hardiman O, Bede P]
Peter Bede, Eoin Finegan, Rangariroyashe Chipika, Taha Omer, Niall Pender, Siobhan Hutchinson, Orla Hardiman, Characterisation of basal ganglia pathology in frontotemporal dementia: a connectivity-based multimodal neuroimaging study, Neurology, 90, (15 Supplement), 2018, pS34.002
Elamin M, Bede P, Montuschi A, Pender N, Chio A, Hardiman O, Predicting prognosis in amyotrophic lateral sclerosis: a simple algorithm, Journal of Neurology, 262, (6), 2015, p1447-1454
Schuster C, Elamin M, Hardiman O, Bede P, Presymptomatic and longitudinal neuroimaging in neurodegeneration: from snapshots to motion picture - a systematic review, J Neurol Neurosurg Psychiatry , 2015
Bede P, Elamin M, Byrne S, McLaughlin RL, Kenna K, Vajda A, Fagan A, Bradley DG, Hardiman O., Patterns of cerebral and cerebellar white matter degeneration in ALS., J Neurol Neurosurg Psychiatry, 86, (4), 2015, p468-470
Bede P, Elamin M, Byrne S, McLaughlin R, Kenna K, Vajda A, Pender N, Bradley DG, Hardiman O, Basal ganglia involvement in Amyotrophic Lateral Sclerosis, Neurology, 81, 2013, p1 - 9
Bede P, Bokde A, Elamin M, Byrne S, McLaughlin RL, Jordan N, Hampel H, Gallagher L, Lynch C, Fagan AJ, Pender N, Hardiman O, Grey matter correlates of clinical variables in amyotrophic lateral sclerosis (ALS): a neuroimaging study of ALS motor phenotype heterogeneity and cortical focality., Journal of neurology, neurosurgery, and psychiatry, 84, (7), 2012, p766-73
Bede P, Walsh R, Fagan A, Hardiman O, "Sand-watch" spinal cord - a case of inferior cervical spinal cord atrophy. , J Neurol. In Press , 2013
Bede P, Bokde AL, Byrne S, Elamin M, Fagan AJ, Hardiman O, Spinal cord markers in ALS: Diagnostic and biomarker considerations., Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 13, (5), 2012, p407-15
Bede P, Elamin M, Byrne S, Hardiman O, Sexual dimorphism in ALS - Exploring gender specific neuroimaging signatures, Amyotroph Lateral Scler. 2013 , 2013
Bede P, Bokde AL, Byrne SC, Elamin M, Walsh RJ, Hardiman O., Waterskier's Hirayama syndrome., Journal of Neurology, 258, (11), 2011, p207 - 207
Bede P, The Role of Magnetic Resonance Imaging in Motor Neuron Disease , Connect, Journal of the IMNDA , October, (10), 2013, p9 - 10
Bede, Peter Hardiman, Orla, Lessons of ALS imaging: Pitfalls and future directions - A critical review, NeuroImage: Clinical, 4, 2014, p436 - 443
Bede P, Oliver D, Stodart J, van den Berg L, Simmons Z, O Brannagáin D, Borasio GD, Hardiman O, Palliative care in amyotrophic lateral sclerosis: a review of current international guidelines and initiatives., Journal of neurology, neurosurgery, and psychiatry, 82, (4), 2011, p413-8
Bede P, Hardiman O, Subcortical gray matter structures: a future biomarker for ALS?, Future Neurology, 9, (2), 2014, p109 - 111
Lebouteux MV, Franques J, Guillevin R, Delmont E, Lenglet T, Bede P, Desnuelle C, Pouget J, Pascal-Mousselard H, Pradat PF, Revisiting the spectrum of lower motor neuron diseases with "snake-eyes" appearance in MRI, European Journal of Neurology, 21, (9), 2014, p1233 - 1241
Byrne S, Elamin M, Bede P, Hardiman O, Absence of consensus in diagnostic criteria for familial neurodegenerative diseases., Journal of neurology, neurosurgery, and psychiatry, 83, (4), 2012, p365-7
Symptomatic Management and Palliative Care in Neurodegenerative Conditions in, NEURODEGENERATIVE DISORDERS: A CLINICAL GUIDE, Springer, 2011, [Bede P, ÓBrannagáin D, Lorenzl S, Oliver D, Hardiman O]
Elamin M, Bede P, Byrne S, Jordan N, Gallagher L, Wynne B, O'Brien C, Phukan J, Lynch C, Pender N, Hardiman O, Cognitive changes predict functional decline in ALS: A population-based longitudinal study., Neurology, 2013
Russell Lewis McLaughlin, Kevin P Kenna, Alice Vajda, Peter Bede, Marwa Elamin, Simon Cronin, Colette G Donaghy, Daniel G Bradley, Orla Hardiman, A second-generation Irish genome-wide association study for amyotrophic lateral sclerosis, Neurobiology of Aging , 36, (2), 2015, p1221.e7-1221.e13
Turner MR, Agosta F, Bede P, Govind V, Lulé D, Verstraete E, Neuroimaging in amyotrophic lateral sclerosis., Biomarkers in medicine, 6, (3), 2012, p319-37
Byrne S, Heverin M, Elamin M, Bede P, Lynch C, Kenna K, Maclaughlin R, Walsh C, Al Chalabi A, Hardiman O., Aggregation of neurologic and neuropsychiatric disease in ALS kindreds: A population based case controlled cohort study of Familial and Sporadic ALS., Ann Neurol. , 10.1002/ana.23969. , (epub), 2013
Byrne S, Elamin M, Bede P, Shatunov A, Walsh C, Corr B, Heverin M, Jordan N, Kenna K, Lynch C, McLaughlin RL, Iyer PM, O'Brien C, Phukan J, Wynne B, Bokde AL, Bradley DG, Pender N, Al-Chalabi A, Hardiman O, Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study., Lancet neurology, 11, (3), 2012, p232-40
Geser F, Prvulovic D, O'Dwyer L, Hardiman O, Bede P, Bokde AL, Trojanowski JQ, Hampel H, On the development of markers for pathological TDP-43 in amyotrophic lateral sclerosis with and without dementia., Progress in neurobiology, 95, (4), 2011, p649-62
Byrne S, Heverin M, Elamin M, Bede P, Lynch C, Hardiman O, Fecundity in ALS, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration , 2013
Byrne S, Bede P, Elamin M, Kenna K, Lynch C, McLaughlin R, Hardiman O, Proposed criteria for familial amyotrophic lateral sclerosis., Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 12, (3), 2011, p157-9
Phukan J, Elamin M, Bede P, Jordan N, Gallagher L, Byrne S, Lynch C, Pender N, Hardiman O, The syndrome of cognitive impairment in amyotrophic lateral sclerosis: a population-based study., Journal of neurology, neurosurgery, and psychiatry, 83, (1), 2012, p102-8
Elamin M, Phukan J, Bede P, Jordan N, Byrne S, Pender N, Hardiman O, Executive dysfunction is a negative prognostic indicator in patients with ALS without dementia., Neurology, 76, (14), 2011, p1263-9
Byrne S, Walsh C, Lynch C, Bede P, Elamin M, Kenna K, McLaughlin R, Hardiman O, Rate of familial amyotrophic lateral sclerosis: a systematic review and meta-analysis., Journal of neurology, neurosurgery, and psychiatry, 82, (6), 2011, p623 - 627
F. Geser, L. O'Dwyer, O. Hardiman, P. Bede, A.L.W. Bokde, D. Prvulovic, John Q. Trojanowski, H. Hampel, On the development of markers for pathological TDP-43 in amyotrophic lateral sclerosis with and without dementia, Progress in Neurobiology, 95, (4), 2011, p649-662
Bede P, MRI study in MND, Connect, Journal of the IMNDA , October, (6), 2011, p9-
Bede P, Oliver D, Stodart J, van den Berg L, Simmons Z, Brannagáin DÓ, Borasio GD, Hardiman O., Palliative care in amyotrophic lateral sclerosis: a review of current international guidelines and initiatives, BMJ Support Palliat Care, 1, (3), 2011, p343 - 348
Bede P Hardiman O, 23. Lessons of ALS imaging: Pitfalls and future directions - A critical review., Neuroimaging Clinical, (4), 2014, p436 - 444
Bede P, Walsh R, Fagan AJ, Hardiman O., "Sand-watch" spinal cord: a case of inferior cervical spinal cord atrophy. , Journal of Neurology, 2014, p235-7
Bede P, Elamin M, Byrne S, Hardiman O, Sexual dimorphism in ALS: exploring gender-specific neuroimaging signatures., Amyotrophic lateral sclerosis & frontotemporal degeneration, 15, (3-4), 2014, p235-43
Byrne S, Heverin M, Bede P, Elamin M, Hardiman O, Fecundity in ALS., Amyotrophic lateral sclerosis & frontotemporal degeneration, 15, (3-4), 2014, p204-6
Byrne S, Heverin M, Elamin M, Bede P, Lynch C, Kenna K, McLaughlin R, Walsh C, Al Chalabi A, Hardiman O, Aggregation of neurologic and neuropsychiatric disease in amyotrophic lateral sclerosis kindreds: a population-based case-control cohort study of familial and sporadic amyotrophic lateral sclerosis., Annals of neurology, 74, (5), 2013, p699-708
Burke T, Wynne B, O'Brien C, Elamin M, Bede P, Hardiman O, Pender, N, Retrospective Investigations of Practice Effects on Repeated Neuropsychological Measures of Executive Functioning, The Irish Journal of Psychology, (April), 2015
J. Machts, K. Loewe, J. Kaufmann, S. Jakubiczk, S. Abdulla, S. Petri, R. Dengler, H.-J. Heinze, M.A. Schoenfeld, S. Vielhaber, P. Bede. , Basal ganglia pathology in amyotrophic lateral sclerosis is associated with cognitive and behavioural changes , Clinical Neurophysiology, 126, (8), 2015, pe97 - e98
H.-P. Müller, G. Grön, S. Abrahams, P. Bede, M. Filippi, F. Agosta, V. Govind, J. Grosskreutz, J. Prudlo, M.R. Turner, J. Kassubek. , Ex post facto structural connectome analysis in ALS at multicenter level: Analysis of over 400 data sets from 8 centers , Clinical Neurophysiology, 126, (8), 2015, pe72 - e73
P Bede, C Schuster, M Elamin,R Mclaughlin, K Kenna, O Hardiman., A connectivity-based analysis of frontostriatal and corticobasal networks in ALS, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 16:sup1, 97-114, 2015
P Bede, C Schuster, M Elamin, R Mclaughlin, K Kenna, O Hardiman. , The selective anatomical vulnerability of ALS - "disease-defining" and "disease defying" brain regions., Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 17, (7-8), 2015, p561 - 570
J Grosskreutz, R Dahnke, C Gaser,T Prell, F Agosta, P Bede, M Benatar,M De Carvalho, S Kalra, J Kassubek,C Reischauer, M Turner, P Van Damme,LH van den Berg, M Weber,M Filippi, NiSALS Quality Control Study Group, Quality control of multicenter, high resolution T1 MRI as a brain biomarker in amyotrophic lateral sclerosis, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 16:sup1, 97-114, 2015
J Machts, K Loewe, J Kaufmann, S Jakubiczka, S Abdulla, S Petri, R Dengler, H-J Heinze, S Vielhaber, MA Schoenfeld, P Bede, Basal ganglia pathology is associated with neuropsychological deficits in c9orf72-negative ALS. , Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 16:sup1, 97-114,, 2015
C Schuster, M Elamin, O Hardiman, P Bede, Phenotype-specific white matter signatures in ALS. , Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 16:sup1, 97-114, 2015
Müller HP, Turner MR, Grosskreutz J, Abrahams S, Bede P, Govind V, Prudlo J, Ludolph AC, Filippi M, Kassubek J, A large-scale multicentre cerebral diffusion tensor imaging study in amyotrophic lateral sclerosis. , J Neurol Neurosurg Psychiatry, jnnp-2015-311952, 2016
Burke T, Elamin M, Bede P, Pinto-Grau M, Lonergan K, Hardiman O, Pender N, Discordant Performance on the 'Reading the Mind in the Eyes' Test, Based on Disease Onset in Amyotrophic Lateral Sclerosis, Amyotroph Lateral Scler Frontotemporal Degener, 17, (7-8), 2016, p467-472
Burke T, Pinto-Grau M, Lonergan K, Elamin M, Bede P, Costello E, Hardiman O, Pender N, Measurement of Social Cognition in Amyotrophic Lateral Sclerosis: A Population Based Study, PLoS One, 11, (8), 2016, pe0160850-
J . Grosskreutz, R. Dahnke, C. Gaser, T. Prell, F. Agosta, P. Bede, M. Benatar, M. de Carvalho, Quality Control Group Article: EP 76. Quality control of high resolution T1 images in the global repository of the neuroimaging society in amyotrophic lateral sclerosis (NiSALS) , Clinical Neurophysiology, 127, (9), 2016, pe270-e271 -
Burke T, Lonergan K, Pinto-Grau M, Elamin M, Bede P, Madden C, Hardiman O & Pender N., Visual Encoding, Consolidation, and Retrieval in Amyotrophic Lateral Sclerosis: Executive Function as a Mediator, and Predictor of Performance., Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2017, p1-9
Elamin M, Pinto-Grau M, Burke T, Bede P, Rooney J, Oâ Sullivan M, Lonergan K, Kirby E, Quinlan E, Breen N, Vajda A, Heverin M, Pender N, Hardiman O, Identifying behavioural changes in ALS: Validation of the Beaumont Behavioural Inventory (BBI), Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 18, (1-2), 2016, p68-73
McLaughlin RL, Kenna KP, Vajda A, Bede P, Elamin M, Cronin S, Donaghy CG, Bradley DG, Hardiman O, Second-generation Irish genome-wide association study for amyotrophic lateral sclerosis., Neurobiology of aging, 36, (2), 2015, p1221.e7-13
Christina Schuster , Orla Hardiman, Peter Bede, Development of an automated MRI-based diagnostic protocol for Amyotrophic Lateral Sclerosis using disease-specific pathognomonic features: a quantitative disease-state classification study, PLoS One, 11, (12), 2016
Elamin M, Pinto-Grau M, Burke T, Bede P, Rooney J, O'Sullivan M, Lonergan K, Kirby E, Quinlan E, Breen N, Vajda A, Heverin M, Pender N, Hardiman O, Identifying behavioural changes in ALS: Validation of the Beaumont Behavioural Inventory (BBI), Amyotroph Lateral Scler Frontotemporal Degener, 28, 2016, p1 - 6
Peter Bede, . From qualitative radiological cues to machine learning: MRI-based diagnosis in neurodegeneration, Future Neurology , 1, 2017, p1 - 4
Peter Bede, Diane Lawlor, Damodar Solanki, Norman Delanty, Carbapenems and Valproate - a consumptive relationship, Epilepsia Open, 2, (1), 2017, p107 - 111
Hardiman, O., Doherty, C.P., Elamin, M., Bede, P (eds), Neurodegenerative Disorders - A Clinical Guide , 2, Springer International Publishing, 2016, 1 - 336pp
C Schuster, O Hardiman, P Bede, Development of an automated MRI-based diagnostic protocol in amyotrophic lateral sclerosis, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 17(Suppl.S1), 2016, p1 - 80
C Schuster, M Elamin, O Hardiman, P Bede, Selective white matter vulnerability in ALS: implications for diagnostic classification, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 17(Suppl. S1), 2016, p215 - 235
Tom Burke, Marta Pinto-Grau, Katie Lonergan, Peter Bede, Meadbh O'Sullivan, Mark Heverin, Alice Vajda, Russell L McLaughlin, Niall Pender, Orla Hardiman., A Cross-sectional population-based investigation into behavioral change in amyotrophic lateral sclerosis: subphenotypes, staging, cognitive predictors, and survival, Annals of Clinical and Translational Neurology , 4, (5), 2017, p305-317
Tarig Abkur, Peter Bede, Reversible gait ataxia: From wheelchair to independent mobility, Neurology, 88, (15), 2017, pe145-e149
Schuster C, Hardiman O, Bede P., Survival prediction in Amyotrophic lateral sclerosis based on MRI measures and clinical characteristics, BMC Neurol, 17, (1), 2017, p73-
Taha Omer, Eoin Finegan, Siobhan Hutchinson, Mark A. Doherty, Alice Vajda, Russell L. McLaughlin, Niall Pender, Orla Hardiman, Peter Bede , Neuroimaging patterns along the ALS-FTD spectrum: a multiparametric imaging study, Amyotroph Lateral Scler Frontotemporal Degener, Epub ahead of print, 2017
Williams JA, Bede P, Doherty CP, An exploration of the spectrum of peri-ictal MRI change; a comprehensive literature review., Seizure, 50, 2017, p19-32
Jennifer Williams, Gerard Mullins, Norman Delanty, Peter Bede, Colin Doherty , The spectrum of peri-ictal MRI changes; four Illustrative cases., Seizure: European Journal of Epilepsy , 50, 2017, p189-193
Iyer PM, Mohr K, Broderick M, Gavin B, Burke T, Bede P, Pinto-Grau M, Pender NP, McLaughlin R, Vajda A, Heverin M, Lalor EC, Hardiman O, Nasseroleslami B, Mismatch Negativity as an Indicator of Cognitive Sub-Domain Dysfunction in Amyotrophic Lateral Sclerosis, Frontiers in Neurology, 8, 2017, p395-
Peter Bede, Eoin Finegan, Orla Hardiman, From pneumomyelography to cord tractography: historical perspectives on spinal imaging., Future Neurol, 12, (3), 2017, p121-124
Peter Bede, Deciphering neurodegeneration: A paradigm shift from focality to connectivity. , Neurology, 89, 2017, p1-2
Nasseroleslami B, Dukic S, Broderick M, Mohr K, Schuster C, Gavin B, McLaughlin R, Heverin M, Vajda A, Iyer PM, Pender N, Bede P, Lalor EC, Hardiman O., Characteristic Increases in EEG Connectivity Correlate With Changes of Structural MRI in Amyotrophic Lateral Sclerosis., Cereb Cortex, 29, (1), 2019, p27 - 41
Bede P, Hardiman O. , Longitudinal structural changes in ALS: a three time-point imaging study of white and gray matter degeneration. , . Amyotroph Lateral Scler Frontotemporal Degener, 2017, p1 - 10
Querin G, El Mendili MM, Bede P, Delphine S, Lenglet T, Marchand-Pauvert V, Pradat PF. , Multimodal spinal cord MRI offers accurate diagnostic classification in ALS. , . J Neurol Neurosurg Psychiatry, 2018
Bede P, El-Kininy N, O'Hara F, Menon P, Finegan E, Healy D, 'Khatatonia' - cathinone-induced hypertensive encephalopathy, Neth J Med., 75, (10), 2017, p448 - 450
Eoin Finegan, Rangariroyashe Chipika, Taha Omer, Siobhan Hutchinson, Mark A. Doherty, Alice Vajda, Russell L. McLaughlin, Orla Hardiman, Peter Bede, The Neuroimaging Profile of Primary Progressive Aphasia, Neurology, 90, (15 Supplement), 2018, pS34.003
Eoin Finegan, Rangariroyashe Chipika, Taha Omer, Mark A. Doherty, Alice Vajda, Russell L. McLaughlin, Niall Pender, Orla Hardiman, Peter Bede, Extra-Motor Pathology in ALS-FTD: Looking Beyond C9orf72, Neurology, 90, (15 Supplement), 2018, pS25.003
Peter Bede, Eoin Finegan, Rangariroyashe Chipika, Orla Hardiman, Machine-learning in neurodegeneration: evaluation, optimisation and validation of MRI-based diagnostic methods, Neurology, 90, (15 Supplement), 2018, pP2.027
Peter Bede, Eoin Finegan, Rangariroyashe Chipika, Orla Hardiman, Evolving models of pseudobulbar affect: historical accounts, controversies, localisation, Neurology, 90, (15 Supplement), 2018, pS39.004
Peter Bede, Eoin Finegan, Rangariroyashe Chipika, Orla Hardiman, Milestones of spinal imaging: myelography in the pre-MRI era, Neurology, 90, (15 Supplement), 2018, pP5.304
Bede P, Querin G, Pradat PF. , The changing landscape of motor neuron disease imaging: the transition from descriptive studies to precision clinical tools. , Curr Opin Neurol. , 2018
Blasco H, Patin F, Descat A, Garçon G, Corcia P, Gelé P, Lenglet T, Bede P, Meininger V, Devos D, Gossens JF, Pradat PF., A pharmaco-metabolomics approach in a clinical trial of ALS: Identification of predictive markers of progression., PLoS One, 13, (6), 2018, pe0198116-
Imaging biomarkers in neurodegenerative conditions in, editor(s)Hardiman, Doherty, Elamin, Bede , Neurodegenerative disorders: A clinical guide - Second Edition, SPRINGER, 2015, [Iyer P, Doherty C, Bede P]
Feron M, Couillandre A, Mseddi E, Termoz N, Abidi M, Bardinet E, Delgadillo D, Lenglet T, Querin G, Welter ML, Le Forestier N, Salachas F, Bruneteau G, Del Mar Amador M, Debs R, Lacomblez L, Meininger V, Pélégrini-Issac M, Bede P, Pradat PF, de Marco G. , Extrapyramidal deficits in ALS: a combined biomechanical and neuroimaging study, J Neurol. , 2018
Christidi F, Karavasilis E, Velonakis G, Ferentinos P, Rentzos M, Kelekis N, Evdokimidis I, Bede P, The Clinical and Radiological Spectrum of Hippocampal Pathology in Amyotrophic Lateral Sclerosis, Front Neurol, 9, (523), 2018
Bede P, Finegan E, Chipika RH, Li Hi Shing S, Lambe J, Meaney J, Redmond J., Occulomotor Neural Integrator Dysfunction in Multiple Sclerosis: Insights From Neuroimaging., Front Neurol., 9, 2018, p691-
Querin G, Lenglet T, Debs R, Stojkovic T, Behin A, Salachas F, Le Forestier N, Amador MDM, Lacomblez L, Meininger V, Bruneteau G, Laforêt P, Blancho S, Marchand-Pauvert V, Bede P, Hogrel JY, Pradat PF. , The motor unit number index (MUNIX) profile of patients with adult spinal muscular atrophy., Clin Neurophysiol, 129, (11), 2018, p2333 - 2340
Querin G, Bede P, Marchand-Pauvert V, Pradat PF., Biomarkers of Spinal and Bulbar Muscle Atrophy (SBMA): A Comprehensive Review., Front Neurol. , 9, (844), 2018
Eoin Finegan, Rangariroyashe H. Chipika, Mark A. Doherty, Russell L. McLaughlin, Parameswaran M. Iyer, Colette Donaghy, Orla Hardiman, Peter Bede, Primary Lateral Sclerosis, part of the MND spectrum or distinct entity: a multiparametric neuroimaging study with comprehensive clinical and genetic profiling, Amyotroph Lateral Scler Frontotemporal Degener, 19, (s1), 2018, p11-
Klomjai W, Roche N, Lamy JC, Bede P, Giron A, Bussel B, Bensmail D, Katz R, Lackmy-Vallee A. , Furosemide unmasks inhibitory dysfunction following spinal cord injury in humans: implication for spasticity. , J Neurotrauma. , 2018
Christidi F, Karavasilis E, Rentzos M, Kelekis N, Evdokimidis I, Bede P., . Clinical and Radiological Markers of Extra-Motor Deficits in Amyotrophic Lateral Sclerosis. , . Front Neurol, 9, 2018
Querin G, El Mendili MM, Lenglet T, Behin A, Stojkovic T, Salachas F, Devos D, Le Forestier N, Del Mar Amador M, Debs R, Lacomblez L, Meninger V, Bruneteau G, Cohen-Adad J, Lehéricy S, Laforêt P, Blancho S, Benali H, Catala M, Li M, Marchand-Pauvert V, Hogrel JY, Bede P, Pradat PF, The spinal and cerebral profile of adult spinal-muscular atrophy: A multimodal imaging study., . Neuroimage Clinical, (18), 2018
Finegan E, Chipika RH, Shing SLH, Hardiman O, Bede P. , Primary lateral sclerosis: a distinct entity or part of the ALS spectrum? , Amyotroph Lateral Scler Frontotemporal Degener. , 2019, p1 - 13
Proudfoot M, Bede P, Turner MR, Imaging Cerebral Activity in Amyotrophic Lateral Sclerosis. , Front Neurol., 9, 2019, p1148-
McMackin R, Bede P, Pender N, Hardiman O, Nasseroleslami B., Neurophysiological markers of network dysfunction in neurodegenerative diseases, Neuroimage Clin, 22, 2019, p101706-
McMackin R, Dukic S, Broderick M, Iyer PM, Pinto-Grau M, Mohr K, Chipika R, Coffey A, Buxo T, Schuster C, Gavin B, Heverin M, Bede P, Pender N, Lalor EC, Muthuraman M, Hardiman O, Nasseroleslami B, Dysfunction of attention switching networks in amyotrophic lateral sclerosis. , Neuroimage Clin, 22, 2019, p101707-
Devos D, Moreau C, Kyheng M, Garçon G, Rolland AS, Blasco H, Gelé P, Timothée Lenglet T, Veyrat-Durebex C, Corcia P, Dutheil M, Bede P, Jeromin A, Oeckl P, Otto M, Meninger V, Danel-Brunaud V, Devedjian JC, Duce JA, Pradat PF, A ferroptosis-based panel of prognostic biomarkers for Amyotrophic Lateral Sclerosis, Sci Rep, 9, (1), 2019, p2918-
Yunusova Y, Plowman EK, Green JR, Barnett C, Bede P. , Clinical Measures of Bulbar Dysfunction in ALS. , Front Neurol. , 10, 2019, p106-
Grollemund V, Pradat PF, Querin G, Delbot F, Le Chat G, Pradat-Peyre JF, Bede P, Machine Learning in Amyotrophic Lateral Sclerosis: Achievements, Pitfalls, and Future Directions, Front Neurosci, 13, 2019, p135-
Chipika RH, Finegan E, Li Hi Shing S, Hardiman O, Bede P. , Tracking a Fast-Moving Disease: Longitudinal Markers, Monitoring, and Clinical Trial Endpoints in ALS, Front Neurol, 10, 2019, p229-
Finegan E, Chipika RH, Li Hi Shing S, Hardiman O, Bede P. , Pathological Crying and Laughing in Motor Neuron Disease: Pathobiology, Screening, Intervention. , Front Neurol., 10, 2019, p260-
Eoin Finegan, Rangariroyashe Chipika, Stacey Li Hi Shing, Mark A. Doherty, Russel McLaughlin, Colette Donaghy, Orla Hardiman, Peter Bede, The Clinical and Neuroimaging Features of Primary Lateral Sclerosis, Neurology, 92, 2019
El Mendili MM, Querin G, Bede P, Pradat PF. , Spinal Cord Imaging in Amyotrophic Lateral Sclerosis: Historical Concepts-Novel Techniques. , Front Neurol, 10, 2019, p350-
Querin G, Bede P, El Mendili MM, Li M, Pélégrini-Issac M, Rinaldi D, Catala M, Saracino D, Salachas F, Camuzat A, Marchand-Pauvert V, Cohen-Adad J, Colliot O, Le Ber I, Pradat PF; Predict to Prevent Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis (PREV-DEMALS) Study Group, Presymptomatic spinal cord pathology in c9orf72 mutation carriers: a longitudinal neuroimaging study, Ann Neurol, 2019
Peter Bede, Eoin Finegan, Rangariroyashe Chipika, Stacey Li Hi Shing, Jeffrey Lambe, Janice Redmond, Nystagmus-associated imaging signatures in Multiple Sclerosis: evaluation of subcortical and infratentorial structures, Neurology, 92, 2019, p(P5. 2-050-
Bede P., The histological correlates of imaging metrics: postmortem validation of in vivo findings, Amyotroph Lateral Scler Frontotemporal Degener, 11, 2019, p1 - 4
Abidi M, de Marco G, Couillandre A, Feron M, Mseddi E, Termoz N, Querin G, Pradat PF, Bede P. , Adaptive functional reorganisation in amyotrophic lateral sclerosis: coexisting degenerative and compensatory changes, Eur J Neurol, 2019
Finegan E, Chipika RH, Li Hi Shing S, Doherty MA, Hengeveld JC, Vajda A, Donaghy C, McLaughlin RL, Pender N, Hardiman O, Bede P, The clinical and radiological profile of primary lateral sclerosis: a population-based study., Journal of Neurology, 2019
Dukic S, McMackin R, Buxo T, Fasano A, Chipika R, Pinto-Grau M, Costello E, Schuster C, Hammond M, Heverin M, Coffey A, Broderick M, Iyer PM, Mohr K, Gavin B, Pender N, Bede P, Muthuraman M, Lalor EC, Hardiman O, Nasseroleslami B., Patterned functional network disruption in amyotrophic lateral sclerosis. , Human Brain Mapping, 40, (16), 2019, p4827 - 4842
Li Hi Shing S, Chipika RH, Finegan E, Murray D, Hardiman O, Bede P, Post-polio Syndrome: More Than Just a Lower Motor Neuron Disease, Front Neurol, 2019
Li Hi Shing S, Chipika RH, Finegan E, Murray D, Hardiman O, Bede P. , Sindrome post-polio: Molto più di una semplice malattia, Frontiers in Neurology, 2019
Marchand-Pauvert V, Peyre I, Lackmy-Vallee A, Querin G, Bede P, Lacomblez L, Debs R, Pradat PF. , Absence of hyperexcitability of spinal motoneurons in patients with ALS. , J Physiol., 2019
Christidi F, Karavasilis E, Rentzos M, Velonakis G, Zouvelou V, Xirou S, Argyropoulos G, Papatriantafyllou I, Pantolewn V, Ferentinos P, Kelekis N, Seimenis I, Evdokimidis I, Bede P. , Hippocampal pathology in amyotrophic lateral sclerosis: selective vulnerability of subfields and their associated projections, Neurobiol Aging, 2019
Bede P, Chipika RH, Finegan E, Li Hi Shing S, Hardiman O. , The anatomical substrate of bulbar impairment in ALS: insights from multiparametric brainstem imaging, corticobulbar connectivity and somatotopic motor cortex measures., Neurology, 2019
Bede P, Chipika RH, Finegan E, Li Hi Shing S, Doherty MA, Hengeveld JC, Vajda A, Hutchinson S, Donaghy C, McLaughlin RL, Hardiman O, Brainstem pathology in amyotrophic lateral sclerosis and primary lateral sclerosis: A longitudinal neuroimaging study, Neuroimage Clin, 2019
Finegan E, Li Hi Shing S, Chipika, RH, Doherty MA, Hengeveld JC, Vajda A, Donaghy C, Pender N, McLaughlin RL, Hardiman O, Bede P., Widespread subcortical grey matter degeneration in primary lateral sclerosis: a multimodal imaging study with genetic profiling., Neuroimage Clin., 2019
Bede P, Pradat PF., Editorial: Biomarkers and Clinical Indicators in Motor Neuron Disease, Frontiers in Neurology, 2019
Christidi F, Karavasilis E, Rentzos M, Velonakis G, Zouvelou V, Xirou S, Argyropoulos G, Papatriantafyllou I, Pantolewn V, Ferentinos P, Kelekis N, Seimenis I, Evdokimidis I, Bede P, Neuroimaging data indicate divergent mesial temporal lobe profiles in amyotrophic lateral sclerosis, Alzheimer's disease and healthy aging, Data in Brief, 2019
Christidi F, Bede P., Mesial temporal lobe metrics in ALS and AD, Mendeley, 2019
Finegan E, Hi Shing SL, Chipika RH, McKenna MC, Doherty MA, Hengeveld JC, Vajda A, Donaghy C, McLaughlin RL, Hutchinson S, Hardiman O, Bede P, Thalamic, hippocampal and basal ganglia pathology in primary lateral sclerosis and amyotrophic lateral sclerosis: Evidence from quantitative imaging data, Data in Brief, 2020
Bede P, Chipika RH, Finegan E, Li Hi Shing S, Chang KM, Doherty MA, Hengeveld JC, Vajda A, Hutchinson S, Donaghy C, McLaughlin RL, Hardiman O., Progressive brainstem pathology in motor neuron diseases: Imaging data from amyotrophic lateral sclerosis and primary lateral sclerosis. , Data in Brief, 2020
Turner MR, Barohn RJ, Corcia P, Fink JK, Harms MB, Kiernan MC, Ravits J, Silani V, Simmons Z, Statland J, van den Berg LH, Ajroud-Driss S, Andrews JA, Babu S, Bede P, Benatar M, Chew S, Conwit R, Cudkowicz M, Carvalho M, Drory VE, Elman L, M Fernandes JA, Ferrey D, Finegan E, Floeter MK, Fournier CN, Govindarajan R, Granit V, Hardiman O, Hayat G, Heiman-Patterson TD, Hübers A, Huey ED, Jawdat O, Kano O, Kisanuki YY, Mackenzie I, Marren D, Morita M, Murphy J, Nations S, Oskarsson B, Paganoni S, Pioro EP, Pullman SL, Rezania K, Rouleau G, Scelsa S, Siddique N, Solano J, Blitterswijk MV, Walk D, Wymer J, Zhao C, Lange D, Mitsumoto H. , Primary lateral sclerosis: consensus diagnostic criteria, J Neurol Neurosurg Psychiatry., 2020
Devos D, Moreau C, Kyheng M, Garçon G, Rolland AS, Blasco H, Gelé P, Lenglet TT, Veyrat-Durebex C, Corcia P, Dutheil M, Bede P, Jeromin A, Oeckl P, Otto M, Meininger V, Danel-Brunaud V, Devedjian JC, Duce JA, Pradat PF., Author Correction: A ferroptosis-based panel of prognostic biomarkers for Amyotrophic Lateral Sclerosis, Scientific Reports, 2020
Meier JM, van der Burgh HK, Nitert AD, Bede P, de Lange SC, Hardiman O, van den Berg LH, van den Heuvel MP, Connectome-Based Propagation Model in Amyotrophic Lateral Sclerosis, Ann Neurol. , 2020
Bede, Peter; Chipika, Rangariroyashe; Finegan, Eoin; Li Hi Shing, Stacey; Chang, Kai Ming; Hardiman, Orla , Medullary, pontine and mesencephalic pathology in ALS and PLS: the segmental brainstem profile of motor neuron disease, Mendeley Data, 2020
F. Christidi, E. Karavasilis, P. Bede, M. Rentzos, G. Velonakis, J. Papatriantafyllou, N. L. Kelekis, I. Seimenis, I. Evdokimidis, A diffusion tensor imaging study of the white matter profile of memory-related tracts in ALS, EPOS European Society of Radiology, 2020
Pradat PF, Bede P. , Biomarkers and clinical indicators in Motor neuron disease, Lausanne: Frontiers Media SA, 2020, 1 - 583pp
Pradat PF, Bernard E, Corcia P, Couratier P, Jublanc C, Querin G, Morélot Panzini C, Salachas F, Vial C, Wahbi K, Bede P, Desnuelle C; French Kennedy's Disease Writing Group., The French national protocol for Kennedy's disease (SBMA): consensus diagnostic and management recommendations. , Orphanet J Rare Dis., 15, (1), 2020, p90-
Bede P, Chipika RH. , Commissural fiber degeneration in motor neuron diseases, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2020
Eoin Finegan, Rangariroyashe Chipika, Stacey Li Hi Shing, Mark A. Doherty, Jennifer C. Hengeveld, Alice Vajda, Colette Donaghy, Russell McLaughlin, Siobhan Hutchinson, Orla Hardiman, Peter Bede, Neuroimaging Reveals Widespread Thalamic, Hippocampal, and Basal Ganglia Atrophy in Primary Lateral Sclerosis, Neurology, 94, (15), 2020
Peter Bede, Efstratios Karavasilis, Michail Rentzos, Georgios Velonakis, Vasiliki Zouvelou, Sofia Xirou, Georgios Argyropoulos, Ioannis Papatriantafyllou, Varvara Pantolewn, Panagiotis Ferentinos, Nikolaos Kelekis, Ioannis Seimenis, Ioannis Evdokimidis, Foteini Christidi, Hippocampal, Fornix, Uncinate, and Amygdala Degeneration in Amyotrophic Lateral Sclerosis: the Pathological Substrate of Memory Impairment, Neurology, 94, (15), 2020
Giorgia Querin, Peter Bede, Mounir El Mendili, Mélanie Péllegrini-Issac, Daisy Rinaldi, Martin Catala, Dario Saracino, Francois Salachas, Agnes Camuzat, Véronique Marchand-Pauvert, Julien Cohen-Adad, Olivier Colliot, Isabelle Le Ber, Pierre-François Pradat., Spinal Cord MRI for Early Detection of Presymptomatic Pathology in c9orf72 Mutation Carriers: A Longitudinal Neuroimaging Study. , Neurology, 94, (15), 2020, p2343-
Peter Bede, Rangariroyashe Chipika, Eoin Finegan, Stacey Li Hi Shing, Mark A. Doherty, Jennifer Hengeveld, Alice Vajda, Siobhan Hutchinson, Colette Donaghy, Russel McLaughlin, Orla Hardiman , Characterising Progressive Brainstem Pathology in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis: In Vivo Insights Based on Computational Imaging, Neurology, 94, (15), 2020
Eoin Finegan, Stacey Li Hi Shing, Rangariroyashe Chipika, Mark A. Doherty, Jennifer C. Hengeveld, Alice Vajda, Colette Donaghy, Russell McLaughlin, Siobhan Hutchinson, Orla Hardiman, Peter Bede, Beyond the Upper Motor Neuron: Extra-motor Involvement in Primary Lateral Sclerosis, Neurology, 94, (15), 2020
Giorgia Querin, Jean-Yves Hogrel, Rabab Debs, Véronique Marchand-Pauvert, Tanya Stojkovic, Anthony Behin, Pascal Laforet, Francois Salachas, Peter Bede, Timothee Lenglet, Pierre-François Pradat, Improvements in the definition of biomarkers for Spinal Muscular Atrophy (SMA) type III and IV: a multimodal longitudinal study, Neurology, 94, (15), 2020
Chipika RH, Finegan E, Li Hi Shing S, McKenna MC, Christidi F, Chang KM, Doherty MA, Hengeveld JC, Vajda A, Pender N, Hutchinson S, Donaghy C, McLaughlin RL, Hardiman O, Bede P. , "Switchboard" malfunction in motor neuron diseases: Selective pathology of thalamic nuclei in amyotrophic lateral sclerosis and primary lateral sclerosis. , Neuroimage Clin. , 2020
Argyropoulos GD, Christidi F, Karavasilis E, Velonakis G, Antoniou A, Bede P, Seimenis I, Kelekis N, Douzenis A, Papakonstantinou O, Efstathopoulos E, Ferentinos P, Cerebro-cerebellar white matter connectivity in bipolar disorder and associated polarity subphenotypes, Prog Neuropsychopharmacol Biol Psychiatry. , 2020
Chipika RH, Christidi F, Finegan E, Li Hi Shing S, McKenna MC, Chang KM, Karavasilis E, Doherty MA, Hengeveld JC, Vajda A, Pender N, Hutchinson S, Donaghy C, McLaughlin RL, Hardiman O, Bede P. , Amygdala pathology in amyotrophic lateral sclerosis and primary lateral sclerosis. , J Neurol Sci. , 2020
Finegan E, Li Hi Shing S, Siah WF, Chipika RH, Chang KM, McKenna MC, Doherty MA, Hengeveld JC, Vajda A, Donaghy C, Hutchinson S, McLaughlin RL, Hardiman O, Bede P. , Evolving diagnostic criteria in primary lateral sclerosis: The clinical and radiological basis of "probable PLS". , J Neurol Sci., 417, 2020
Grollemund V, Chat GL, Secchi-Buhour MS, Delbot F, Pradat-Peyre JF, Bede P, Pradat PF. , Development and validation of a 1-year survival prognosis estimation model for Amyotrophic Lateral Sclerosis using manifold learning algorithm UMAP. , Scientific Reports, 10, (1), 2020
Bede P, Siah WF, McKenna MC, Li Hi Shing S., Consideration of C9orf72-associated ALS-FTD as a neurodevelopmental disorder: insights from neuroimaging. , J Neurol Neurosurg Psychiatry., 2020
Grollemund V, Le Chat G, Secchi-Buhour MS, Delbot F, Pradat-Peyre JF, Bede P, Pradat PF. , Manifold learning for amyotrophic lateral sclerosis functional loss assessment : Development and validation of a prognosis model, J Neurol, 2020
Abidi M, de Marco G, Grami F, Termoz N, Couillandre A, Querin G, Bede P, Pradat PF., Neural Correlates of Motor Imagery of Gait in Amyotrophic Lateral Sclerosis. , J Magn Reson Imaging., 2020
Querin G, Bede P, Saracino D, Colliot O, Pradat PF, Le Ber I; PREV-DEMALS Study Group, IRM médullaire pour un diagnostic précoce des porteurs asymptomatiques de la mutation C9orf72 : étude longitudinale, Rev Neurol (Paris), 176, 2020
Finegan E, Siah WF, Shing SLH, Chipika RH, Chang KM, McKenna MC, Doherty MA, Hengeveld JC, Vajda A, Donaghy C, Hutchinson S, McLaughlin RL, Hardiman O, Bede P. , Imaging and clinical data indicate considerable disease burden in 'probable' PLS: Patients with UMN symptoms for 2-4 years., Data in Brief, 32, 2020
Chipika RH, Siah WF, Shing SLH, Finegan E, McKenna MC, Christidi F, Chang KM, Karavasilis E, Vajda A, Hengeveld JC, Doherty MA, Donaghy C, Hutchinson S, McLaughlin RL, Hardiman O, Bede P. , MRI data confirm the selective involvement of thalamic and amygdalar nuclei in amyotrophic lateral sclerosis and primary lateral sclerosis., Data in Brief, 2020
G.Querin, J.Hogrel, R.Debs, V.Marchand-Pauvert, T.Stojkovic, A.Behin, P.Lafôret, F.Salachas, P.Bede, P.Pradat, T.Lenglet , Improvements in the definition of biomarkers for Spinal Muscular Atrophy (SMA) type III and IV: a multimodal longitudinal study, Neuromuscular Disorders , 30, (S46-S150), 2020, pP181-
Chipika RH, Siah WF, McKenna MC, Li Hi Shing S, Hardiman O, Bede P., The presymptomatic phase of amyotrophic lateral sclerosis: are we merely scratching the surface?, J Neurol, 2020
Bede P, Bogdahn U, Lope J, Chang KM, Xirou S, Christidi F. , Degenerative and regenerative processes in Amyotrophic Lateral Sclerosis: motor reserve, adaptation and putative compensatory changes. , Neural Regen Res, 16, (6), 2021, p1208 - 1209
Querin G, Lenglet T, Debs R, Stojkovic T, Behin A, Salachas F, Le Forestier N, Amador MDM, Bruneteau G, Laforêt P, Blancho S, Marchand-Pauvert V, Bede P, Hogrel JY, Pradat PF, Development of new outcome measures for adult SMA type III and IV: a multimodal longitudinal study. , J Neurol., 2021
Li Hi Shing S, McKenna MC, Siah WF, Chipika RH, Hardiman O, Bede P. , The imaging signature of C9orf72 hexanucleotide repeat expansions: implications for clinical trials and therapy development. , Brain Imaging Behav. , 2021
Tahedl M, Chipika RH, Lope J, Li Hi Shing S, Hardiman O, Bede P. , Cortical progression patterns in individual ALS patients across multiple timepoints: a mosaic-based approach for clinical use, J Neurol., 2021
Finegan E, Shing SLH, Chipika RH, Chang KM, McKenna MC, Doherty MA, Hengeveld JC, Vajda A, Pender N, Donaghy C, Hutchinson S, McLaughlin RL, Hardiman O, Bede P. , Extra-motor cerebral changes and manifestations in primary lateral sclerosis. , Brain Imaging Behav., 2021
McMackin R, Dukic S, Costello E, Pinto-Grau M, McManus L, Broderick M, Chipika R, Iyer PM, Heverin M, Bede P, Muthuraman M, Pender N, Hardiman O, Nasseroleslami B. , Cognitive network hyperactivation and motor cortex decline correlate with ALS prognosis., Neurobiol Aging, 104, 2021, p57-70
Li Hi Shing S, Lope J, McKenna MC, Chipika RH, Hardiman O, Bede P. , . Increased cerebral integrity metrics in poliomyelitis survivors: putative adaptation to longstanding lower motor neuron degeneration. , J Neurol Sci., 424, 2021, p117361
Theodosiou T, Christidi F, Xirou S, Bede P, Karavasilis E, Papadopoulos C, Kourtesis P, Pantoleon V, Kararizou E, Papadimas G, Zalonis I., Neuropsychological Assessment Should Always be Considered in Myotonic Dystrophy Type 2. , Cogn Behav Neurol., 34, (1), 2021, p1-10
Li Hi Shing S, Lope J, Chipika RH, Hardiman O, Bede P., Extra-motor manifestations in post-polio syndrome (PPS): fatigue, cognitive symptoms and radiological features. , Neurol Sci. , 2021
Mitsumoto H, Turner MR; all Delegates of the PLS Conference, Ajroud-Driss S, Andres P, Andrews J, Gomez EA, Atehortua JMS, Babu S, Barohn R, Bede P, Benatar M, Chew S, Conwit R, Corcia P, Cudkowicz M, Davis F, Carvalho M, Drory V, Elman L, Factor-Litvak P, Fernandes JAM, Ferrey D, Finegan E, Fink J, Floeter MK, Fournier C, Genge A, Govindarajan R, Granit V, Haase G, Hardiman O, Harms M, Hayat G, Heiman-Patterson T, Hill B, Hübers A, Huey E, Jawdat O, Kano O, Kau K, Kiernan M, Kisanuki Y, Kurent J, Kwan J, Lange D, Ludolph A, Mackenzie I, Manfredi G, Marren D, Morita M, Murphy J, Nations S, Oskarsson B, Paganoni S, Pellerin D, Ravits J, Rezania K, Rouleau G, Scelsa S, Siddique T, Siddique N, Silani V, Simmons Z, Statland J, Traynor B, Blitterswijk MV, Berg LVD, Walk D, Warden D, Wymer J., Preface: promoting research in PLS: current knowledge and future challenges., Amyotroph Lateral Scler Frontotemporal Degener., (21), 2020, p1-2
Pioro EP, Turner MR, Bede P., Neuroimaging in primary lateral sclerosis., Amyotroph Lateral Scler Frontotemporal Degener., 21, 2020, p18-27
Costello E, Rooney J, Pinto-Grau M, Burke T, Elamin M, Bede P, McMackin R, Dukic S, Vajda A, Heverin M, Hardiman O, Pender N. , Cognitive reserve in amyotrophic lateral sclerosis (ALS): a population-based longitudinal study. , J Neurol Neurosurg Psychiatry. , 92, (5), 2021, p460-465
McKenna MC, Chipika RH, Li Hi Shing S, Christidi F, Lope J, Doherty MA, Hengeveld JC, Vajda A, McLaughlin RL, Hardiman O, Hutchinson S, Bede P., Infratentorial pathology in frontotemporal dementia: cerebellar grey and white matter alterations in FTD phenotypes., J Neurol., 2021
Bede P, Chipika RH, Christidi F, Hengeveld JC, Karavasilis E, Argyropoulos GD, Lope J, Li Hi Shing S, Velonakis G, Dupuis L, Doherty MA, Vajda A, McLaughlin RL, Hardiman O. , Genotype-associated cerebellar profiles in ALS: focal cerebellar pathology and cerebro-cerebellar connectivity alterations. , J Neurol Neurosurg Psychiatry., 2021
Bede P, Pradat PF, Lope J, Vourc'h P, Blasco H, Corcia P., Primary Lateral Sclerosis:Clinical, radiological and molecular features., Rev Neurol (Paris), 2021, pS0035-3787-
Corcia P, Bede P, Pradat PF, Couratier P, Vucic S, de Carvalho M., Split-hand and split-limb phenomena in amyotrophic lateral sclerosis: pathophysiology, electrophysiology and clinical manifestations., J Neurol Neurosurg Psychiatry., 2021
Tahedl M, Murad A, Lope J, Hardiman O, Bede P. , Evaluation and categorisation of individual patients based on white matter profiles: Single-patient diffusion data interpretation in neurodegeneration. , J Neurol Sci., 2021
Bede P, Siah WF. , The diagnostic challenge of Primary Lateral Sclerosis: the integration of clinical, genetic and radiological cues. , Eur J Neurol. , 2021
Li Hi Shing S, Lope J, Chipika RH, Hardiman O, Bede P. , Imaging data indicate cerebral reorganisation in poliomyelitis survivors: Possible compensation for longstanding lower motor neuron pathology. , Data Brief., 38, 2021
McKenna MC, Corcia P, Couratier P, Siah WF, Pradat PF, Bede P. , Frontotemporal Pathology in Motor Neuron Disease Phenotypes: Insights From Neuroimaging., Front Neurol., 12, 2021
Bede P, Murad A, Hardiman O. , Pathological neural networks and artificial neural networks in ALS: diagnostic classification based on pathognomonic neuroimaging features., J Neurol., 2021
Eisen A, Bede P., The strength of corticomotoneuronal drive underlies ALS split phenotypes and reflects early upper motor neuron dysfunction., Brain Behav., 2021
Tahedl M, Li Hi Shing S, Finegan E, Chipika RH, Lope J, Hardiman O, Bede P., Propagation patterns in motor neuron diseases: Individual and phenotype-associated disease-burden trajectories across the UMN-LMN spectrum of MNDs., Neurobiol Aging., 2021
Dukic S, McMackin R, Costello E, Metzger M, Buxo T, Fasano A, Chipika R, Pinto-Grau M, Schuster C, Hammond M, Heverin M, Coffey A, Broderick M, Iyer PM, Mohr K, Gavin B, McLaughlin R, Pender N, Bede P, Muthuraman M, van den Berg L, Hardiman O, Nasseroleslami B. , Resting-state EEG reveals four subphenotypes of amyotrophic lateral sclerosis., Brain, 2021
The Diagnosis and Management of Motor Neurone Disease. in, Marie Murray , Living with motor neurone disease: a complete guide. , Atrium, Cork University Press., 2021, [Li Hi Shing S, Lope J, Bede P. ]
Bede P, Murad A, Lope J, Li Hi Shing S, Finegan E, Chipika RH, Hardiman O, Chang KM., Phenotypic categorisation of individual subjects with motor neuron disease based on radiological disease burden patterns: A machine-learning approach. , J Neurol Sci. , 2021
McKenna MC, Tahedl M, Lope J, Chipika RH, Li Hi Shing S, Doherty MA, Hengeveld JC, Vajda A, McLaughlin RL, Hardiman O, Hutchinson S, Bede P. , Mapping cortical disease-burden at individual-level in frontotemporal dementia: implications for clinical care and pharmacological trials., Brain Imaging Behav. , 2021
Li Hi Shing S, Bede P., The neuroradiology of upper motor neuron degeneration: PLS, HSP, ALS., Amyotroph Lateral Scler Frontotemporal Degener., 2021
Tahedl M, Li Hi Shing S, Finegan E, Chipika RH, Lope J, Murad A, Hardiman O, Bede P., Imaging data reveal divergent longitudinal trajectories in PLS, ALS and poliomyelitis survivors: Group-level and single-subject traits, Data Brief. , 2021
Finegan E, Siah WF, Li Hi Shing S, Chipika RH, Hardiman O, Bede P. , Cerebellar degeneration in primary lateral sclerosis: an under-recognized facet of PLS. , Amyotroph Lateral Scler Frontotemporal Degener. , 2022
McKenna MC, Tahedl M, Murad A, Lope J, Hardiman O, Hutchinson S, Bede P. , White matter microstructure alterations in frontotemporal dementia: Phenotype-associated signatures and single-subject interpretation. , Brain Behav., 2022
Le Gall L, Duddy WJ, Martinat C, Mariot V, Connolly O, Milla V, Anakor E, Ouandaogo ZG, Millecamps S, Lainé J, Vijayakumar UG, Knoblach S, Raoul C, Lucas O, Loeffler JP, Bede P, Behin A, Blasco H, Bruneteau G, Del Mar Amador M, Devos D, Henriques A, Hesters A, Lacomblez L, Laforet P, Langlet T, Leblanc P, Le Forestier N, Maisonobe T, Meininger V, Robelin L, Salachas F, Stojkovic T, Querin G, Dumonceaux J, Butler Browne G, González De Aguilar JL, Duguez S, Pradat PF., Muscle cells of sporadic amyotrophic lateral sclerosis patients secrete neurotoxic vesicles. , J Cachexia Sarcopenia Muscle., 2022
McKenna MC, Murad A, Huynh W, Lope J, Bede P. , The changing landscape of neuroimaging in frontotemporal lobar degeneration: from group-level observations to single-subject data interpretation. , Expert Rev Neurother. , 2022
McKenna MC, Li Hi Shing S, Murad A, Lope J, Hardiman O, Hutchinson S, Bede P. , Focal thalamus pathology in frontotemporal dementia: Phenotype-associated thalamic profiles., J Neurol Sci., 2022
Bede P, Murad A, Lope J, Hardiman O, Chang KM., Clusters of anatomical disease-burden patterns in ALS: a data-driven approach confirms radiological subtypes., J Neurol. , 2022
Shing SLH, Murad A, Lope J, Hardiman O, Bede P. , Cerebellar remodelling decades after spinal cord insult: neuroplasticity in poliomyelitis survivors. , J Integr Neurosci., 21, (2), 2022, p65-
Bede P, Lope J., Biomarker development in Amyotrophic Lateral Sclerosis: challenges and viable strategies. , Eur J Neurol. , 2022
Chipika RH, Mulkerrin G, Pradat PF, Murad A, Ango F, Raoul C, Bede P., Cerebellar pathology in motor neuron disease: neuroplasticity and neurodegeneration. , Neural Regen Res. , 17, (11), 2022, p2335 - 2341
Abidi M, Pradat PF, Termoz N, Couillandre A, Bede P, de Marco G., Motor imagery in amyotrophic lateral Sclerosis: An fMRI study of postural control. , Neuroimage Clin., 35, 2022
Christidi F, Karavasilis E, Argyropoulos GD, Velonakis G, Zouvelou V, Murad A, Evdokimidis I, Rentzos M, Seimenis I, Bede P., Neurometabolic Alterations in Motor Neuron Disease: Insights from Magnetic Resonance Spectroscopy. , J Integr Neurosci., 21, (3), 2022, p87-
Chipika RH, Mulkerrin G, Murad A, Lope J, Hardiman O, Bede P. , Alterations in somatosensory, visual and auditory pathways in amyotrophic lateral sclerosis: an under-recognised facet of ALS., J Integr Neurosci., 21, (3), 2022, p88-
Bede P, Chang KM, Tan EL., Machine-learning in Motor Neuron Diseases: Prospects and Pitfalls., Eur J Neurol., 2022
Theodosiou T, Christidi F, Xirou S, Karavasilis E, Bede P, Papadopoulos C, Argyropoulos GD, Kourtesis P, Pantolewn V, Ferentinos P, Kararizou E, Velonakis G, Zalonis I, Papadimas G. , Executive Dysfunction, Social Cognition Impairment, and Gray Matter Pathology in Myotonic Dystrophy Type 2: A Pilot Study. , Cogn Behav Neurol. , 2022
McKenna MC, Lope J, Tan EL, Bede P., Pre-symptomatic radiological changes in frontotemporal dementia: propagation characteristics, predictive value and implications for clinical trials. , Brain Imaging Behav., 2022
Mulkerrin G, França MC Jr, Lope J, Tan EL, Bede P., Neuroimaging in hereditary spastic paraplegias: from qualitative cues to precision biomarkers. , Expert Rev Mol Diagn., 2022
McKenna MC, Redmond J, Bradley D, Bede P., Teaching NeuroImage: Primary Familial Brain Calcification in SLC20A2 Genotype. , Neurology, 2022
Argyropoulos GD, Christidi F, Karavasilis E, Bede P, Antoniou A, Velonakis G, Seimenis I, Kelekis N, Smyrnis N, Papakonstantinou O, Efstathopoulos E, Ferentinos P., Predominant polarity as a neurobiological specifier in bipolar disorder: Evidence from a multimodal neuroimaging study., Prog Neuropsychopharmacol Biol Psychiatry. , 123, 2023, p110718-
McKenna MC, Lope J, Bede P, Tan EL. , Thalamic pathology in frontotemporal dementia: Predilection for specific nuclei, phenotype-specific signatures, clinical correlates, and practical relevance., Brain Behav., 13, (2), 2023, pe2881-
Tahedl M, Tan EL, Shing SLH, Chipika RH, Siah WF, Hengeveld JC, Doherty MA, McLaughlin RL, Hardiman O, Finegan E, Bede P. , Not a benign motor neuron disease: longitudinal imaging captures relentless motor connectome disintegration in primary lateral sclerosis, Eur J Neurol. , 2023
Christidi F, Argyropoulos GD, Karavasilis E, Velonakis G, Zouvelou V, Kourtesis P, Pantoleon V, Tan EL, Daponte A, Aristeidou S, Xirou S, Ferentinos P, Evdokimidis I, Rentzos M, Seimenis I, Bede P., Hippocampal Metabolic Alterations in Amyotrophic Lateral Sclerosis: A Magnetic Resonance Spectroscopy Study. , Life (Basel), 2023
Quigley S, Yiannakas MC, Bede P, Meaney J, Kearney H., Neuropathologically informed imaging of cortical grey matter lesions in MS - A pilot study., Mult Scler Relat Disord., 2023
Tahedl M, Tan EL, Chipika RH, Hengeveld JC, Vajda A, Doherty MA, McLaughlin RL, Siah WF, Hardiman O, Bede P. , Brainstem-cortex disconnection in amyotrophic lateral sclerosis: bulbar impairment, genotype associations, asymptomatic changes and biomarker opportunities., J Neurol., 2023
Bede P, Lulé D, Müller HP, Tan EL, Dorst J, Ludolph AC, Kassubek J. , Presymptomatic grey matter alterations in ALS kindreds: a computational neuroimaging study of asymptomatic C9orf72 and SOD1 mutation carriers. , J Neurol., 2023
McFarlane R, Galvin M, Heverin M, Mac Domhnaill É, Murray D, Meldrum D, Bede P, Bolger A, Hederman L, Impey S, Stephens G, O'Meara C, Wade V, Al Chalabi A, Chiò A, Corcia P, van Damme P, Ingre C, McDermott C, Povedanos M, van den Berg L, Hardiman O., PRECISION ALS-an integrated pan European patient data platform for ALS., Amyotroph Lateral Scler Frontotemporal Degener., 2023
Tan EL, Bede P, Pradat PF., Promises and pitfalls of imaging-based biomarkers in motor neuron diseases., Curr Opin Neurol. , 2023
Tahedl M, Tan EL, Siah WF, Hengeveld JC, Doherty MA, McLaughlin RL, Hardiman O, Finegan E, Bede P., Radiological correlates of pseudobulbar affect: Corticobulbar and cerebellar components in primary lateral sclerosis., J Neurol Sci. , 451, 2023, p120726-
Bede P, Chipika RH, Tan EL., Imaging extra-motor dysfunction in motor neuron disease: achievements and controversies. , Amyotroph Lateral Scler Frontotemporal Degener., 2023
Bede P, Pradat PF. , The gap between academic advances and therapy development in motor neuron disease. , Curr Opin Neurol., 36, (4), 2023, p335 - 337
Tahedl M, Tan EL, Chipika RH, Lope J, Hengeveld JC, Doherty MA, McLaughlin RL, Hardiman O, Hutchinson S, McKenna MC, Bede P., The involvement of language-associated networks, tracts, and cortical regions in frontotemporal dementia and amyotrophic lateral sclerosis: Structural and functional alterations., Brain Behav. , 2023
Tan EL, Tahedl M, Lope J, Hengeveld JC, Doherty MA, McLaughlin RL, Hardiman O, Chang KM, Finegan E, Bede P., Language deficits in primary lateral sclerosis: cortical atrophy, white matter degeneration and functional disconnection between cerebral regions., J Neurol. , 2023
McMackin R, Bede P, Ingre C, Malaspina A, Hardiman O., Biomarkers in amyotrophic lateral sclerosis: current status and future prospects., Nat Rev Neurol., 2023
Metzger M, Dukic S, McMackin R, Giglia E, Mitchell M, Bista S, Costello E, Peelo C, Tadjine Y, Sirenko V, Plaitano S, Coffey A, McManus L, Farnell Sharp A, Mehra P, Heverin M, Bede P, Muthuraman M, Pender N, Hardiman O, Nasseroleslami B., Functional network dynamics revealed by EEG microstates reflect cognitive decline in amyotrophic lateral sclerosis., Hum Brain Mapp., 2023
Tan EL, Lope J, Bede P., Primary lateral sclerosis: more than just an upper motor neuron disease., Neural Regen Res., 2024
Dukic S, Fasano A, Coffey A, Buxó T, McMackin R, Chipika R, Heverin M, Bede P, Muthuraman M, Lowery M, Carson RG, Hardiman O, Nasseroleslami B., Electroencephalographic ß-band oscillations in the sensorimotor network reflect motor symptom severity in amyotrophic lateral sclerosis., Eur J Neurol., 2024
McKenna MC, O'Connor A, Lockhart A, Bogdanova-Mihaylova P, Brett F, Langan Y, Meaney J, Costigan D, Doherty CP, Bede P, Murphy SM, Hutchinson S., POLR3A-related disorders: expanding the clinical phenotype., J Neurol., 2024
Kleinerova J, Tahedl M, Tan EL, Delaney S, Hengeveld JC, Doherty MA, McLaughlin RL, Hardiman O, Chang KM, Finegan E, Bede P., Supra- and infra-tentorial degeneration patterns in primary lateral sclerosis: a multimodal longitudinal neuroradiology study., J Neurol., 2024
McKenna MC, Hutchinson S, Bede P., Cerebellar involvement in frontotemporal dementia: the infratentorial imaging signatures of FTD phenotypes., J Neurol Neurosurg Psychiatry., 94, (A26), 2023
Tan EL, Lope J, Bede P., Harnessing Big Data in Amyotrophic Lateral Sclerosis: Machine Learning Applications for Clinical Practice and Pharmaceutical Trials., J Integr Neurosci., 23, (3), 2024
Argyropoulos GD, Christidi F, Karavasilis E, Bede P, Velonakis G, Antoniou A, Seimenis I, Kelekis N, Smyrnis N, Papakonstantinou O, Efstathopoulos E, Ferentinos P., A Magnetic Resonance Spectroscopy Study on Polarity Subphenotypes in Bipolar Disorder., Diagnostics (Basel)., 14, (11), 2024
Tahedl M, Tan EL, Kleinerova J, Delaney S, Hengeveld JC, Doherty MA, Mclaughlin RL, Pradat PF, Raoul C, Ango F, Hardiman O, Chang KM, Lope J, Bede P., Progressive Cerebrocerebellar Uncoupling in Sporadic and Genetic Forms of Amyotrophic Lateral Sclerosis., Neurology, 103, (2), 2024