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Professor Connail Mc Crory
Clinical Professor, Surgery
Clinical Professor, Trinity Inst. of Neurosciences (TCIN)

Publications and Further Research Outputs

Peer-Reviewed Publications

Galvin D, McCrory C, The role of T lymphocytes in neuropathic pain initiation, development of chronicity and treatment, Brain Behaviour & Immunity Health, 2021 Journal Article, 2021

Mullins CF, Walsh S, Rooney A, McCrory C, Das B, A preliminary prospective observational study of the effectiveness of a high concentration capsaicin cutaneous patch in the management of chronic post surgical neuropathic pain, Irish Journal of Medical Science, 2021 Journal Article, 2021

Galvin D, McCrory C, The role of T lymphocytes in neuropathic pain initiation, development of chronicity and treatment, Brain Behaviour and Immunity Health, 2021 Journal Article, 2021 DOI

Royds J, Cassidy H, Conroy M, Dunne MR, Matallanas D, Lysaght J, McCrory C, An investigation into the proteomic constituents of cerebrospinal fluid in patients with chronic peripheral neuropathic pain medicated with opioids - A pilot study, J Neuroimmune Pharmacology, 2020 Journal Article, 2020

Royds J, Cassidy H, Conroy M, Dune M.R, Lysaght J, McCrory C, Examination and characterisation of the effect of amitriptyline therapy for chronic neuropathic pain on neuropeptide and proteomic constituents of human cerebrospinal fluid, Brain, Behaviour & Immunity, 2020 Journal Article, 2020 DOI

Royds J, Conroy M, Cassidy H, Lysaght J, McCrory C, Examination and Characterisation of the effect of Burst Spinal Cord Stimulation on the the cerebrospinal fluid cellular, peptide and proteomic constituents in patient responders with chronic neuropathic pain, J. Neuroimmunology, 2020 Journal Article, 2020 URL

Royds J, Conroy MJ, Dunne MR, McCrory C, Lysaght J., An investigation into the modulation of Tcell phenotypes by amitriptyline and nortriptyline, European Neuropsychopharmacology, 2020 Journal Article, 2020 DOI URL

Connail McCrory, Trial Stimulation period before implanting a spinal cord stimulator, Health Product Regulatory Authority, 2020 Report, 2020

Gopal H, Kehoe E, Hegarty F, Bodke A, McCrory C, Pressure Pain transduction in cortical ands-cortical areas of the brain in healthy volunteers: Does it matter if it is pressure or thermal stimulus?, 2019 Working Paper, 2019

Gopal H, Kehoe E, Hegarty F, Bodke A, McCrory C, Investigation of cerebral site of action of oxycodone in the presence of external pressure stimulus on non-dominant thumb in patients with chronic lumbar radiculopathy: An event related fMRI study, 2019 Working Paper, 2019

Gopal H, Kehoe E, Hegarty F,Bodke A, McCrory C, A comparison of brain areas response to pressure pain stimulus in healthy volunteers and patients with chronic lumbar radiculopathy, 2019 Working Paper, 2019

Aine O Gara Connail McCrory Basabit Das, Dorsal root ganglion pulsed radiofrequency treatment for chronic cervical radicular pain: a retrospective review of outcomes in fifty-nine cases, Irish Journal of Medical Science, 2019 Journal Article, 2019

Das, B. and Conroy, M. and Moore, D. and Lysaght, J. and McCrory, C., Human dorsal root ganglion pulsed radiofrequency treatment modulates cerebrospinal fluid lymphocytes and neuroinflammatory markers in chronic radicular pain, Brain, Behavior, and Immunity, 70, 2018, p157-165 Journal Article, 2018 DOI

Royds J McCrory, Neuroimmunity and Chronic Pain, British Journal of Anaesthesia Education, 18, (12), 2018, p377 - 383 Journal Article, 2018

CMcCrory, Painful Diabetic Neuropathy, World Institute of Pain, Nijmegen, Netherlands, 2017 Invited Talk, 2017

The extended role of the Clinical Engineers - advancing healthcare in, Health Technology Management, CRC Press, 2017, [F Hegarty, CMcCrory] Book Chapter, 2017

Robb LP, Cooney JM, McCrory CR, Evaluation of spinal cord stimulation on the symptoms of anxiety and depression and pain intensity in patients with failed back surgery syndrome., Irish journal of medical science, 2017 Journal Article, 2017

Walczuk P, McCrory C, New Technologies in Spinal Cord Stimulation, Rheumatology and Pain, 3, 2017, p56 - 57 Journal Article, 2017

David Moore, Connail McCrory, The Proteomics of Intrathecal Analgesic agents for Chronic Pain, Current Neuropharmacology, 15, (2), 2017, p198--205 Journal Article, 2017

CMcCrory, New pain Therapeutic Techniques, Royal College of Anaesthetists ASM, London, 2017 Invited Talk, 2017

CMcCrory, Pain Medicine - The Future, Faculty of Pain Medicine, RCOA, London, 2017 Invited Talk, 2017

Hari Gopal, Joseph Fitzgerald, Connail McCrory, Spinal cord stimulation for FBSS and CRPS: A review of 80 cases with on-table trial of stimulation, Journal of Back and Musculoskeletal Rehabilitation, 29, (1), 2016, p7--13 Journal Article, 2016

Patricia Duff, Basabjit Das, Connail McCrory, Percutaneous radiofrequency rhizotomy for cervical zygapophyseal joint mediated neck pain: A retrospective review of outcomes in forty-four cases, Journal of Back and Musculoskeletal Rehabilitation, 29, (1), 2016, p1--5 Journal Article, 2016

Moore D McCrory C, Spinal Cord Stimulation, British Journal of Anaesthesia Education, 16, (8), 2016, p258 - 263 Journal Article, 2016

CMcCrory, Pulsed radio frequency Treatment: Where are we?, Faculty of Pain Medicine RCOA ASM, London, 2015 Invited Talk, 2015

CMcCrory, CSF neuropeptides and Pain perception, 9th Neuroscience Ireland Conference, Dublin City University, 2015 Invited Talk, 2015

Richard M. Talbot, Kevin F. McCarthy, Connail McCrory, Central and systemic inflammatory responses to thoracotomy - Potential implications for acute and chronic postsurgical pain, Journal of Neuroimmunology, 285, 2015, p147--149 Journal Article, 2015

CMcCrory, Optimising patient outcomes in chronic spinal pain, Irish Rheumatology ASM, Kilkenny, 2015, Irish Rheumatology Society Invited Talk, 2015

McCarthy KF, McCrory C, Cerebrospinal fluid levels of glial cell-derived neurotrophic factor correlate with spinal cord stimulation frequency in patients with neuropathic pain: a preliminary report., Spinal cord, 2014 Journal Article, 2014

Ward V McCrory C, An assessment of intrathecal catheters in the preoperative period, Irish Journal of Medical Science, 183, (2), 2014, p293 - 296 Journal Article, 2014

CMcCrory, Complex Regional pain Syndrome Diagnosis and Management, Faculty of Occupational Health ASM, RCPI, 2014 Invited Talk, 2014

Hari Gopal, Connail Mc Crory, Coccygodynia treated by pulsed radio frequency treatment to the Ganglion of Impar: A case series, Journal of Back and Musculoskeletal Rehabilitation, 27, (3), 2014, p349--354 Journal Article, 2014

CMcCrory, Management of Chronic Cervical Pain, Faculty of Occupational Health, 2014 Invited Talk, 2014

CMcCrory, Role of CSF Neuropeptides in Chronic Pain Perception, TCIN Scientific Meeting, TCIN, 2014 Invited Talk, 2014

Das B, McCrory C, Spinal cord stimulation in pregnancy with failed back surgery syndrome., Irish medical journal, 2014 Journal Article, 2014

Connail McCrory et al, HIQA Report: A series of health technology assessments (HTA) of clinical referralor treatment thresholds for selected procedures, Dublin, 2014 Report, 2014

Kevin F. McCarthy, Thomas J. Connor, Connail McCrory, Cerebrospinal Fluid Levels of Vascular Endothelial Growth Factor Correlate With Reported Pain and Are Reduced by Spinal Cord Stimulation in Patients With Failed Back Surgery Syndrome, Neuromodulation: Technology at the Neural Interface, 16, (6), 2013, p519--522 Journal Article, 2013

CMcCrory, Clinical pain perception, Faculty of Pain Medicine, 2013 Invited Talk, 2013

Duff P, Daly C, McCrory C, Ambulatory postoperative ward-based epidural analgesia: a retrospective review of 1,147 cases., Irish journal of medical science, 2012 Journal Article, 2012

CMcCrory, Effect of Rhizotomy and Spinal Cord Stimulation on spinal neuroimmune peptide biosynthesis in vivo in man, Guys&Thomas' Annual Interventional Pain Meeting, London, 2011 Invited Talk, 2011

C McCrory, K McCarthy, Acute neuroimmune response to lumbar rhizotomy, Pain Practice, 5th World Congress of World Institute of Pain, New York, 2009, 2009 Conference Paper, 2009

C McCrory, , Implanted Pain Therapy Devices and Patients in the Intensive Care unit, Intensive Care meeting, Adelaide, S. Australia, 2009, Flinders Hospital Invited Talk, 2009

Louise Brennan, Joseph Fitzgerald, Connail McCrory, The Use of Pulsed Radiofrequency Treatment for Chronic Benign Pancreatitis Pain, Pain Practice, 9, (2), 2009, p135--140 Journal Article, 2009

Louise K. Brennan, Brian H. Harte, Desmond J. Fitzgerald, Connail R. McCrory, Surgery Induces Cyclooxygenase-2 Expression in the Rat Cervical Spinal Cord, Regional Anesthesia and Pain Medicine, 34, (6), 2009, p549--552 Journal Article, 2009

R Talbot CMcCrory, Human Cerebrospinal Fluid cytokines and interventional pain therapies, 2008 Invited Talk, 2008

Harney DF, Dooley M, Harhen B, McGuiness N, Cagney G, McCrory C, Fitzgerald DJ, Dowd NP., Nimesulide 90 mg orally twice daily does not influence postoperative morphine requirements after major chest surgery, Anesth Analg. , 106, (1), 2008, p294-300 Journal Article, 2008

Malgorzata Krajnik, Connail McCrory, Steve Allen, Management Strategies for Neuropathic Pain in Different European Countries, Journal Of Pain & Palliative Care Pharmacotherapy, 21, (2), 2007, p49--52 Journal Article, 2007

C.McCrory, D. Westerling, Polycythaemia Vera Presenting as Complex Regional Pain Syndrome of the Lower Limbs, Clinical Journal of Pain, 17, 2005, p236 - 238 Journal Article, 2005

Connail McCrory, Desmond Fitzgerald, Spinal Prostaglandin Formation and Pain Perception Following Thoracotomy, Chest, 125, (4), 2004, p1321--1327 Journal Article, 2004

Mechanisms of Postoperative Neuropathic Pain in, editor(s)Shorten G , Postoperative Pain Management, Elsevier Science, 2004, pp40 - 62, [R Talbot, C McCrory] Book Chapter, 2004

Connail R. McCrory, Sten G. E. Lindahl, Cyclooxygenase Inhibition for Postoperative Analgesia, Anesthesia & Analgesia, 95, (1), 2002, p169--176 Journal Article, 2002

Connail McCrory, Dara Diviney, Jeanne Moriarty, David Luke, Desmond Fitzgerald, Comparison between repeat bolus intrathecal morphine and an epidurally delivered bupivacaine and fentanyl combination in the management of post-thoracotomy pain with or without cyclooxygenase inhibition, Journal of Cardiothoracic and Vascular Anesthesia, 16, (5), 2002, p607--611 Journal Article, 2002

McCrory C Fitzgerald D, Pharmacology of COX-2 inhibitors in man. Anti-inflammatory and analgesic actions of nimesulide, Drugs, 37, 2001, p15 - 20 Journal Article, 2001

CMcCrory D Fitzgerald, Pharmacology of COX-2 inhibition in man; antiinflamatory and analgesic actions of Nimesulide, Congress of European Association of Clinical Pharmacology and Therapeutics, Florence, Italy, 2000 Invited Talk, 2000

C. McCrory, A. Jinna, N. Hughes, Unexpected left atrial occlusion secondary to oesophageal tumor t erminates anesthesia, Canadian Journal of Anaesthesia, 46, 1999, p999 - 1000 Journal Article, 1999

CMcCrory, Dara Diviney, Jeanne Moriarty, David Luke, Desmond Fitzgerald, A comparison between repeat bolus intrathecal morphine and an epidurally delivered bupivicaine/fentanyl combination in the management ofpost-thoracotomy pain and the effect of cyclooxygenase inhibition on both therapeutic modalities, Post graduate Asembly in Anesthesiology, New York, 1999 Poster, 1999

C McCrory, L Browne, Abnormal lumbar transverse process- A cause of treatable low back pain in young adults, The Pain Clinic, 3, 1998, p193 - 195 Journal Article, 1998

Colbert SA, McCrory C, O'Hanlon DM, Scully M, Tanner A, Doyle M, A prospective study comparing intravenous tenoxicam with rectal diclofenac for pain relief in day case surgery., European journal of anaesthesiology, 1998 Journal Article, 1998

C. McCrory, S.A. Colbert, M. Doherty, M. Abrahams, C. Cooney, Commonly used Anaesthetic Drugs and Solutions change the PH of Propofol Emulsion, C. McCrory, S.A. Colbert, M. Doherty, M. Abrahams, C. Cooney, Western Anaesthetic Symposium, 1998 Poster, 1998

Connail McCrory, Niall Hughes, An interesting case of shunting, Journal of Cardiothoracic and Vascular Anesthesia, 12, (5), 1998, p565--566 Journal Article, 1998

C. McCrory, M. Ryan, P. Doherty, Falsely Reassuring Pulse Oximetry in the presence of Severe Hypoxia, The Canadian Journal of Anaesthesia, 44, 1997, p1323 - 1324 Journal Article, 1997

C. McCrory, K. Crowley, Is repeat explorative laparotomy of value in patients with sepsis in the Intensive Care Unit?, Irish Journal of Medical Science, 166, 1997, p88 - 91 Journal Article, 1997

C. McCrory, W. Blunnie, D. Moriarty, Elective Tracheal Intubation in Cervical Spine Injuries, Irish Medical Journal, 90, 1997, p234 - 235 Journal Article, 1997

McCrory C Crowley K, Is repeat exploitative laparotomy of value in patients with sepsis in the intensive care unit, Irish Journal of Medical Science, 166, 1997, p88 - 91 Journal Article, 1997

B. Lyons, C. McCrory, J O'Connor, V. Hannon, Does Aminophylline augment the bronchodilator effect of Volatile Anaesthetic agents : an in vitro study, Faculty of Anaesthetists RCSI, Annual Scientific Meeting, May, 1997 Invited Talk, 1997

McCrory C Cunningham A, Low dose dopamine- will there ever be a scientific rationale, British Journal of Anaesthesia, 78, 1997, p350 - 351 Journal Article, 1997

C McCrory, J Keaveney, Spinal Cors Stimulation - The Beaumont Experience, The Pain Clinic, 10, 1997, p123 - 128 Journal Article, 1997

CMcCrory, Alan McShane, The laryngeal mask airway is associated with reflux in the lithotomy position, Anaesthetic Research Society , Birmingham UK, 1996 Conference Paper, 1996

C. McCrory, J. O'Connor, J. Boylan, V. Hannon, Effects of Desflurane and Halothane on Isolated Rat Aortic Smooth Muscle, The International Anaesthetic Research Society Meeting, Washington, DC, March, 1996 Poster, 1996

C. McCrory, J. O'Connor, J. Boylan, V. Hannon, Effects of Desflurane and Halothane on Isolated Rat Aortic Smooth Muscle, Anesthesia and Analgesia, 82, (2S), 1996 Journal Article, 1996

Connail McCrory, Denis Moriarty, Mallampati Grade and Laryngeal Mask Placement, Anesthesia & Analgesia, 82, (5), 1996, p1112--1113 Journal Article, 1996

D. Hughes, C. McCrory, E. Aziz, C. O'Herlihy, J. Kelly, D. O'Keefe, Electrotransdermal delivery of Hydromorphone for Postoperative Analgesia, National Scientific Meeting, April, 1995 Poster, 1995

C. McCrory, D. O'Keefe, Two Unusual Cases of Intractable Chronic Pain Treated Successfully with Intrathecal Morphine, Registrar's Prize Meeting, Slieve Russell Hotel, Ballyconnell, Co. Cavan, 1995 Invited Talk, 1995

D. Hughes, C. McCrory, E. Aziz, C. O'Herlihy, J. Kelly, D. O'Keefe, Electrotransdermal delivery of Hydromorphone for postoperative analgesia, Irish Journal of Medical Science, 164, (14), 1995, p40 - 40 Journal Article, 1995

C. McCrory, B. Marsh, R. Hone, D. Phelan, European Nosocomial Infection Survey: Analysis of Irish Data, National Scientific Meeting, Royal College of Physicians, April, 1995 Poster, 1995

C. McCrory, D. Moriarty, Assessment of Laryngeal Mask Airway Positioning in Adults, Young Investigators Meeting, Mater Misericordiae Hospital, 6th May, 1994 Invited Talk, 1994

C. McCrory, B. Marsh, R. Hone, D. Phelan, European Nosocomial Infection Survey: Analysis of Irish Data, Irish Journal of Medical Science, 163, (13), 1994, p1 - 1 Journal Article, 1994

C. McCrory, K. Crowley, Is Repeat Explorative Laparotomy of value in patients with sepsis in the Intensive Care Unit?, The Intensive Care Society Meeting, Hudson Bay Hotel, Athlone, 19th November, 1994 Poster, 1994

CmCCrory D Moriarty, Assessment of Laryngeal Mask Airway Positioning in Adults, National Scientific Meeting, 1994 Conference Paper, 1994

CmcCrory, B Marsh, R. Hone, D Phelan, European Nosocmial Infection survey: Analysis of Irish data, National Scientific Meeting, Royal College of Physicians of Ireland, 1994 Poster, 1994

Non-Peer-Reviewed Publications

Debra Galvin Connail McCrory, Management of difficult chronic pain conditions, Medical Independent, 2019 Review, 2019

Research Expertise

Keywords

BACK PAIN; CEREBROSPINAL FLUID; CHRONIC PAIN; Cytokine modulation of immune responses; IMMUNE CELLS; IMMUNE-MEDIATED; NEUROMODULATION

Recognition

Representations

Dean, Faculty of Pain Medicine, CAI Elected to this position by board of the Faculty of Pain Medicine. Responsible for running the Faculty functions: National Training Scheme in Pain Medicine. Fellow of Faculty of Pain Medicine examinations part 1 and 2 and revision courses. Dealing with reciprocity issues for non-eu doctors wishing to work in Ireland. Interacting with other colleges, RCSI, RCPI and ICGP. 2015

Editor Pain Medicine section of British Journal of Anaesthesia Education. 2015

Opioid prescribing group. Collaborative project between the Faculty of Pain Medicine, CAI and ICGP. This group was established at the request of the HSE to formulate national policy on opioid prescribing. A policy document was submitted to Department of Health. 2015

External Examiner Fellowship in Pain Medicine of the Faculty of Pain Medicine, Royal College of Anaesthetists, London 2019

Health Information and Quality Assessment (HIQA). I was appointed by College of Anaesthetists to this board and was a member of Expert Advisory Group on interventional procedures. This was part of the "Safe Better Care"programme and I was an author on the the national policy document: A series of health technology assessments of clinical referral and treatment thresholds for selected procedures 2014 2014

Member of the local organising committee for 9th World Institute of Pain Meeting in Dublin in 2019 with 2200 attendees. Chaired the organising committee of the Faculty of Pain Medicine of Ireland Annual Scientific meeting for 3 years ( approx 200 attendees per meeting). Member of local organising committee for the combined meeting of the Faculty of Pain Medicine of Ireland with the Neuromodulation Society of UK & Ireland in Cork in 2008 with approximately 400 attendees. 2008

Examiner for Final MB, Final FPMCAI, FInal FCAI. 2010

Neuromodualtion Society of United Kingdom & Ireland. I was elected as the Irish Representative on this committee.This provided links to neuromodulation resaerch funding and faciltated access to Fellowship traing programmes in neuromodulation in UK for Irish doctors completing their pain medicine training in Ireland. 2005

Chairman Pharmacy & Therapeutics committee, St. James Hospital, Dublin. I was a board member 2003-4 and then elected as chairman. I initiated the Nurse Prescribing initiative at St. James Hospital and also negociated with CEO and CFO to finance the building of the new medication storage unit at St. James. 2005

Expert Advisory Role for Pfizer regarding development and clinical application of Pregabalin (Lyrica) 2006

Expert Advisory group for clinical implementation of patch therapy Qutenza for neuropathic pain 2013

External reviewer for the following journals: Pain Medicine, Pain, British Journal of Anaesthesia, Regional Anesthesia & Pain Medicine 2010

Irish Medical Organisation - NCHD representative 1996

Expert advisor to Health Products Regulatory Authority : National Practice document regarding the role of :Trial of Stimulation for Spinal Cord Stimulation

Awards and Honours

Clinical Research Medal in Pain Medicine march 2019

Editors Award for Best paper - Neuromodulation ref: Neuromodulation 2013:16(6);519-22 2013

Memberships

Fellow of College of Anaesthetists of Ireland 1993 – current

Irish Hospital Consultants Association 2002 – Current

Neuromodulation Society of UK & Ireland 2004 – current

Fellow of World Institute of Pain 2005 – current

Fellow of Faculty of Pain Medicine, College of Anaesthetists of Ireland 2008 – current

Irish Pain Society - member 2008 – current

Fellow of American Academy of Pain Medicine 2015 – current