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Professor Ignacio Martin-Loeches
Clinical Professor, Clinical Medicine

Biography

Dr. Ignacio Martin-Loeches, MD, PhD, FJFICMI is a full-time Consultant in Intensive Care Medicine at St. James's Hospital and Professor at Trinity College Dublin, Ireland.

He serves as Chair of the Acute Critical Care Group at the European Respiratory Society (ERS) and is the elected Chair for Research at the European Society of Intensive Care Medicine (ESICM).

Previously, he was the Chair of CoBaTrICE (International Competency-Based Training Programme in Intensive Care Medicine for Europe and other world regions) under ESICM and an elected council member of the World Federation of Societies of Intensive and Critical Care Medicine. He is also a Steering Committee member and executive member of the research working group of the Surviving Sepsis Campaign (SSC).

Dr. Martin-Loeches is the Principal Investigator of multiple projects funded by European Regional Development Funds (ERDF), Science Foundation Ireland (SFI), and the European Network for ICU-related infections (ENIRRIs) under ERS.

He has authored over 600 peer-reviewed publications, accumulating more than 37,445 citations. His h-index is 98, and his i10-index is 358, reflecting his significant impact on critical care and infectious diseases research.

Publications and Further Research Outputs

Peer-Reviewed Publications

Luis Felipe Reyes, Antoni Torres, Juan Olivella, Elsa D. Ibáñez-Prada, Saad Nseir, Otavio T. Ranzani, Pedro Povoa, EMILIO DIAZ, prof. Marcus J. Schultz, Alejandro Rodriguez , CRISTIAN C. SERRANO-MAYORGA, Gennaro De Pascale, Paolo Navalesi, Szymon Skoczy"ski, Mariano Esperatti, Luis Coelho, Andrea Cortegiani, Stefano Aliberti, Anselmo Caricato, Helmut J. F. Salzer, Adrian Ceccato, Rok "ivljak, Paolo Maurizio Soave, Charles-Edouard Luyt, Pervin Korkmaz Ekren, Fernando Rios, Joan Ramon Masclans, Judith Marin, Silvia Iglesias-Moles, STEFANO NAVA, Davide Chiumello, Lieuwe D. Bos, artigas antonio, Filipe Froes, David Grimaldi, Mauro Panigada, Fabio Silvio Taccone, Massimo Antonelli, Prof. Ignacio martin-loeches, Factors Associated with Mortality in Nosocomial Lower Respiratory Tract Infections: An ENIRRI Analysis, Antibiotics, 14, (2), 2025, p127 Journal Article, 2025

Ingrid G. Bustos, Lina F. Martinez-Lemus, Luis Felipe Reyes, Prof. Ignacio martin-loeches, Transforming Microbiological Diagnostics in Nosocomial Lower Respiratory Tract Infections: Innovations Shaping the Future, Diagnostics, 15, (3), 2025, p265 Journal Article, 2025

Alejandro Rodriguez , Julen Berrueta, Carolina Páez, Ronny Huertas, Marco Marotta, Laura Claverias, Josep Gómez, Sandra Trefler, FREDERIC GOMEZ, María Dolores Guerrero-Torres, Sergio Pardo-Granell, Ester Picó-Plana, Alicia Selles-Sánchez, Francisco Javier Candel, Prof. Ignacio martin-loeches, MARIA BODÍ, Ten-Year Evaluation of Ventilator-Associated Pneumonia (VAP) According to Initial Empiric Treatment: A Retrospective Analysis Using Real-World Data, Biomedicines, 13, (2), 2025, p360 Journal Article, 2025

Alexis Garduno, Prof. Ignacio martin-loeches, Targeting Sepsis: Disease Tolerance, Immune Resilience, and Compartmentalized Immunity, Biomedicines, 12, (11), 2024, p2420 Journal Article, 2024

Ana Cysneiros, Tiago Alexandre dos Santos Galvão, Nuno Domingues, Pedro Mendes Jorge, Luís Bento, Prof. Ignacio martin-loeches, ARDS Mortality Prediction Model Using Evolving Clinical Data and Chest Radiograph Analysis, Biomedicines, 12, (2), 2024, p439 Journal Article, 2024

Paulo Mergulhão, João Gonçalves-Pereira, Antero Fernandes, Andriy Krystopchuk, J Miguel Ribeiro, Daniel Miranda, Heloísa Castro, Carla Eira, Juvenal Morais, Cristina Lameirão, Sara Gomes, Dina Leal, Joana Duarte, Leonor Pássaro, Filipe Froes, Prof. Ignacio martin-loeches, Epidemiology and Burden of Ventilator-Associated Pneumonia among Adult Intensive Care Unit Patients: A Portuguese, Multicenter, Retrospective Study (eVAP-PT Study), Antibiotics, 13, (4), 2024, p290 Journal Article, 2024

Ignasi Sacanella, ERIKA ESTEVE-PITARCH, Jessica Guevara-Chaux, Julen Berrueta, Alejandro García-Martínez, Josep Gómez, Cecilia Casarino, Florencia Alés, Laura Canadell, Prof. Ignacio martin-loeches, Santiago Grau, Francisco Javier Candel, MARIA BODÍ, Alejandro Rodriguez , A Real-World Data Observational Analysis of the Impact of Liposomal Amphotericin B on Renal Function Using Machine Learning in Critically Ill Patients, Antibiotics, 13, (8), 2024, p760 Journal Article, 2024

Rachael Cusack, Elizabeth Little, Prof. Ignacio martin-loeches, Practical Lessons on Antimicrobial Therapy for Critically Ill Patients, Antibiotics, 13, (2), 2024, p162 Journal Article, 2024

Gustavo Sganzerla Martinez, Alexis Garduno, Ali Toloue Ostadgavahi, Benjamin Hewins, Mansi Dutt, Anuj Kumar, Prof. Ignacio martin-loeches, David J. Kelvin, Identification of Marker Genes in Infectious Diseases from ScRNA-seq Data Using Interpretable Machine Learning, International Journal of Molecular Sciences, 25, (11), 2024, p5920 Journal Article, 2024

Alejandro Rodriguez , Josep Gómez, Prof. Ignacio martin-loeches, Laura Claverias, EMILIO DIAZ, Rafael Zaragoza, Marcio Borges-Sa, Frederic Gómez-Bertomeu, Álvaro Franquet Bonet, Sandra Trefler, Carlos González Garzón, Lissett Cortés, Florencia Alés, Susana Sancho, Jordi Solé-Violán, Angel Estella, Julen Berrueta, Alejandro García-Martínez, Borja Suberviola, Juan J. Guardiola, MARIA BODÍ, A Machine Learning Approach to Determine Risk Factors for Respiratory Bacterial/Fungal Coinfection in Critically Ill Patients with Influenza and SARS-CoV-2 Infection: A Spanish Perspective, Antibiotics, 13, (10), 2024, p968 Journal Article, 2024

Prof. Ignacio martin-loeches, Giampaolo Maggi, EMILIO DIAZ, Judith Marín-Corral, Alfonso Guedea, Marcos I. Restrepo, Luis Felipe Reyes, Alejandro Rodríguez, A Multicentric Observational Study to Determine Myocardial Injury in Severe Community-Acquired Pneumonia (sCAP), Antibiotics, 12, (12), 2023, p1710 Journal Article, 2023

Ignacio Martin-Loeches, Jean Chastre, Richard G. Wunderink, Bronchoscopy for diagnosis of ventilator-associated pneumonia, Intensive Care Medicine, 49, (1), 2023, p79-82 Journal Article, 2023

Leone, Marc, Einav, Sharon, Antonucci, Elio, Depret, Francois, Lakbar, Ines, Martin-Loeches, Ignacio, Wieruszewski, Patrick M., Myatra, Sheila Nainan, Khanna, Ashish K., Multimodal strategy to counteract vasodilation in septic shock, Anaesthesia, Critical Care & Pain Medicine, 42, (3), 2023, p101193 Journal Article, 2023

Martinez, Gustavo Sganzerla, Ostadgavahi, Ali Toloue, Al-Rafat, Abdullah Mahmud, Garduno, Alexis, Cusack, Rachael, Bermejo-Martin, Jesus Francisco, Martin-Loeches, Ignacio, Kelvin, David, Model-interpreted outcomes of artificial neural networks classifying immune biomarkers associated with severe infections in ICU, Frontiers in Immunology, 14, 2023 Journal Article, 2023

Moreno, G., Ruiz-Botella, M., Martin-Loeches, I, Gomez Alvarez, J., Jimenez Herrera, M., Bodi, M., Armestar, F., Marques Parra, A., Estella, A., Trefler, S., Jorge Garcia, R., Murcia Paya, J., Vidal Cortes, P., Diaz, E., Ferrer, R., Albaya-Moreno, A., Socias-Crespi, L., Bonell Goytisolo, J. M., Sancho Chinesta, S., Loza, A., Forcelledo Espina, L., Pozo Laderas, J. C., DeAlba-Aparicio, M., Sanchez Montori, L., Vallverdu Perapoch, I, Hidalgo, V, Fraile Gutierrez, V, Casamitjana Ortega, A. M., Martin Serrano, F., Nieto, M., Blasco Cortes, M., Marin-Corral, J., Sole-Violan, J., Rodriguez, A., A differential therapeutic consideration for use of corticosteroids according to established COVID-19 clinical phenotypes in critically ill patients, Medicina Intensiva, 47, (1), 2023, p23-33 Journal Article, 2023

Manrique, Sara, Claverias, Laura, Magret, Monica, Masclans, Joan Ramon, Bodi, Maria, Trefler, Sandra, Canadell, Laura, Diaz, Emili, Sole-Violan, Jordi, Bisbal-Andres, Elena, Gonzalez Natera, Ruth, Albaya Moreno, Antonio, Vallverdu, Montserrat, Carlos Ballesteros, Juan, Socias, Lorenzo, Gordo Vidal, Federico, Sancho, Susana, Martin-Loeches, Ignacio, Rodriguez, Alejandro, Timing of intubation and ICU mortality in COVID-19 patients: a retrospective analysis of 4198 critically ill patients during the first and second waves, BMC Anesthesiology, 23, (1), 2023 Journal Article, 2023

Alexis Garduno, Gustavo Sganzerla Martinez, Ali Toloue Ostadgavahi, David Kelvin, Rachael Cusack, Ignacio Martin-Loeches, Parallel Dysregulated Immune Response in Severe Forms of COVID-19 and Bacterial Sepsis via Single-Cell Transcriptome Sequencing, Biomedicines, 11, (3), 2023, p778 Journal Article, 2023

Ines Lakbar, Sharon Einav, Nathalie Lalevée, Prof. Ignacio martin-loeches, Bruno Pastene, Marc Leone, Interactions between Gender and Sepsis"Implications for the Future, Microorganisms, 11, (3), 2023, p746 Journal Article, 2023

Raquel Carbonell garcía, Gerard Moreno, Prof. Ignacio martin-loeches, María Bodí, Alejandro Rodríguez, The Role of Biomarkers in Influenza and COVID-19 Community-Acquired Pneumonia in Adults, Antibiotics, 12, (1), 2023, p161 Journal Article, 2023

Reyes, Luis Felipe, Garcia-Gallo, Esteban, Murthy, Srinivas, Fuentes, Yuli, V, Serrano, Cristian C., Ibanez-Prada, Elsa D., Lee, James, Rojek, Amanda, Citarella, Barbara Wanjiru, Goncalves, Bronner P., Dunning, Jake, Ratsep, Indrek, Vinan-Garces, Andre Emilio, Kartsonaki, Christiana, Rello, Jordi, Martin-Loeches, Ignacio, Shankar-Hari, Manu, Olliaro, Piero L., Merson, Laura, Major adverse cardiovascular events (MACE) in patients with severe COVID-19 registered in the ISARIC WHO clinical characterization protocol: A prospective, multinational, observational study, Journal of Critical Care, 77, 2023, p154318 Journal Article, 2023

Martin-Loeches, Ignacio, Povoa, Pedro, Nseir, Saad, Ventilator associated tracheobronchitis and pneumonia: one infection with two faces, Intensive Care Medicine, 49, (8), 2023, p996-999 Journal Article, 2023

David, Sascha, Russell, Lene, Castro, Pedro, van de Louw, Andry, Zafrani, Lara, Pirani, Tasneem D., Nielsen, Nathan, Mariotte, Eric L., Ferreyro, Bruno T., Kielstein, Jan, Montini, Luca C., Brignier, Anne, Kochanek, Matthias, Cid, Joan, Robba, Chiara, Martin-Loeches, Ignacio, Ostermann, Marlies P., Juffermans, Nicole, Research priorities for therapeutic plasma exchange in critically ill patients, Intensive Care Medicine Experimental, 11, (1), 2023 Journal Article, 2023

Rafael Zaragoza, Jordi Sole Violan, Rachel Cusack, Alejandro Rodriguez, Luis Felipe Reyes, Prof. Ignacio martin-loeches, Invasive Pulmonary Aspergillosis: Not Only a Disease Affecting Immunosuppressed Patients, Diagnostics, 13, (3), 2023, p440 Journal Article, 2023

Foucrier, Arnaud, Roquilly, Antoine, Bachelet, Delphine, Martin-Loeches, Ignacio, Bougle, Adrien, Timsit, Jean-Francois, Montravers, Philippe, Zahar, Jean-Ralph, Eloy, Philippine, Weiss, Emmanuel, ASPIC Study Grp, Antimicrobial Stewardship for Ventilator Associated Pneumonia in Intensive Care (the ASPIC trial): study protocol for a randomised controlled trial, BMJ Open, 13, (2), 2023, pe065293 Journal Article, 2023

Antonucci, Elio, Polo, Tania, Giovini, Manuela, Girardis, Massimo, Martin-Loeches, Ignacio, Nielsen, Nathan D., Lozsan, Francisco Jose Chacon, Ferrer, Ricard, Lakbar, Ines, Leone, Marc, Refractory septic shock and alternative wordings: A systematic review of literature, Journal of Critical Care, 75, 2023, p154258 Journal Article, 2023

Adrian Ceccato, Marta Camprubí-Rimblas, Lieuwe D. J. Bos, Pedro Povoa, Prof. Ignacio martin-loeches, Carles Forne, Aina Areny Balagueró, Elena Campaña-Duel, Luis Morales-Quinteros, Sara Quero, Paula Ramírez, Mariano Esperatti, Antonio Torres, Lluis Blanch, artigas antonio, Evaluation of the Kinetics of Pancreatic Stone Protein as a Predictor of Ventilator-Associated Pneumonia, Biomedicines, 11, (10), 2023, p2676 Journal Article, 2023

De Pascale, Gennaro, Martin-Loeches, Ignacio, Nseir, Saad, Antifungal stewardship in critically ill patients, Intensive Care Medicine, 49, (6), 2023, p681-684 Journal Article, 2023

Gaffney, Sarah, Kelly, Dearbhla M., Rameli, Puteri Maisarah, Kelleher, Eoin, Martin-Loeches, Ignacio, Invasive pulmonary aspergillosis in the intensive care unit: current challenges and best practices, APMIS, 131, (11), 2023, p654-667 Journal Article, 2023

Cusack, Rachael, Bos, Lieuwe D., Povoa, Pedro, Martin-Loeches, Ignacio, Endothelial dysfunction triggers acute respiratory distress syndrome in patients with sepsis: a narrative review, Frontiers in Medicine, 10, 2023 Journal Article, 2023

Martin-Loeches, Ignacio, Leone, Marc, Einav, Sharon, Antibiotic stewardship: Dead bugs do not mutate, Journal of Translational Internal Medicine, 10, (4), 2023, p290-293 Journal Article, 2023

Alexis Garduno, Rachael Cusack, Marc Leone, Sharon Einav, Prof. Ignacio martin-loeches, Multi-Omics Endotypes in ICU Sepsis-Induced Immunosuppression, Microorganisms, 11, (5), 2023, p1119 Journal Article, 2023

Antunes, Bianca B. P., Silva, Amanda A. B., Nunes, Patricia H. C., Martin-Loeches, Ignacio, Kurtz, Pedro, Hamacher, Silvio, Bozza, Fernando A., Antimicrobial consumption and drug utilization patterns among COVID-19 and non-COVID-19 patients, Journal of Antimicrobial Chemotherapy, 78, (3), 2023, p840-849 Journal Article, 2023

Martin-Loeches, Ignacio, Shorr, Andrew F., Wunderink, Richard G., Kollef, Marin H., Timsit, Jean-Francois, Yu, Brian, Huntington, Jennifer A., Jensen, Erin, Bruno, Christopher J., Outcomes in participants with ventilated nosocomial pneumonia and organ failure treated with ceftolozane/tazobactam versus meropenem: a subset analysis of the phase 3, randomized, controlled ASPECT-NP trial, Annals of Intensive Care, 13, (1), 2023 Journal Article, 2023

Roberts, Jason A., Nicolau, David P., Martin-Loeches, Ignacio, Deryke, C. Andrew, Losada, Maria C., Du, Jiejun, Patel, Munjal, Rizk, Matthew L., Paschke, Amanda, Chen, Luke F., Imipenem/cilastatin/relebactam efficacy, safety and probability of target attainment in adults with hospital-acquired or ventilator-associated bacterial pneumonia among patients with baseline renal impairment, normal renal function, and augmented renal clearance, JAC-Antimicrobial Resistance, 5, (2), 2023 Journal Article, 2023

Russell, Lene, Pene, Frederic, Martin-Loeches, Ignacio, Multidrug-resistant bacteria in the grey shades of immunosuppression, Intensive Care Medicine, 49, (2), 2023, p216-218 Journal Article, 2023

Martin-Loeches, Ignacio, Torres, Antoni, Nagavci, Blin, Aliberti, Stefano, Antonelli, Massimo, Bassetti, Matteo, Bos, Lieuwe D., Chalmers, James D., Derde, Lennie, De Waele, Jan, Garnacho-Montero, Jose, Kollef, Marin, Luna, Carlos M., Menendez, Rosario, Niederman, Michael S., Ponomarev, Dmitry, Restrepo, Marcos I., Rigau, David, Schultz, Marcus J., Weiss, Emmanuel, Welte, Tobias, Wunderink, Richard, ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia (Apr, 10.1007/s00134-023-07033-8, 2023), Intensive Care Medicine, 49, (8), 2023, p1040-1041 Journal Article, 2023

Ronan MacLoughlin, Ignacio Martin-Loeches, Not all nebulizers are created equal: Considerations in choosing a nebulizer for aerosol delivery during mechanical ventilation, Expert Review of Respiratory Medicine, 17, (2), 2023, p131-142 Journal Article, 2023

Sonneville, Romain, de Montmollin, Etienne, Contou, Damien, Ferrer, Ricard, Gurjar, Mohan, Klouche, Kada, Sarton, Benjamine, Demeret, Sophie, Bailly, Pierre, da Silva, Daniel, Escudier, Etienne, Le Guennec, Loic, Chabanne, Russel, Argaud, Laurent, Salem, Omar Ben Hadj, Thyrault, Martial, Frerou, Aurelien, Louis, Guillaume, De Pascale, Gennaro, Horn, Janneke, Helbok, Raimund, Geri, Guillaume, Bruneel, Fabrice, Martin-Loeches, Ignacio, Taccone, Fabio Silvio, De Waele, Jan, Ruckly, Stephane, Staiquly, Quentin, Citerio, Giuseppe, Timsit, Jean-Francois, EURECA Investigator Study Grp, Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA): an international prospective multicenter cohort study, Intensive Care Medicine, 49, (5), 2023, p517-529 Journal Article, 2023

Caceres, Eder, Olivella, Juan C., Yanez, Miguel, Vinan, Emilio, Estupinan, Laura, Boada, Natalia, Martin-Loeches, Ignacio, Reyes, Luis Felipe, Risk factors and outcomes of lower respiratory tract infections after traumatic brain injury: a retrospective observational study, Frontiers in Medicine, 10, 2023 Journal Article, 2023

Einav, Sharon, Leone, Marc, Martin-Loeches, Ignacio, Sepsis and antibiotics: When should we deploy a parachute?, International Journal of Antimicrobial Agents, 61, (4), 2023, p106732 Journal Article, 2023

Ignacio Martin-Loeches, Antoni Torres, Blin Nagavci, Stefano Aliberti, Massimo Antonelli, Matteo Bassetti, Lieuwe Bos, James D. Chalmers, Lennie Derde, Jan de Waele, Jose Garnacho-Montero, Marin Kollef, Carlos Luna, Rosario Menendez, Michael Niederman, Dmitry Ponomarev, Marcos Restrepo, David Rigau, Marcus J. Schultz, Emmanuel Weiss, Tobias Welte, Richard Wunderink, ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia, European Respiratory Journal, 61, (4), 2023, p2200735 Journal Article, 2023

Liselotte Hol, prof. Marcus J. Schultz, Prof. Ignacio martin-loeches, David M. P. van Meenen, Ary Serpa Neto, Frederique Paulus, PRoAcT-COVID Investigators, Differences in Ventilation Management and Outcomes between the Two First Waves of the COVID-19 Pandemic"A Comparison between Two Nationwide Observational Studies in The Netherlands, Journal of Clinical Medicine, 12, (13), 2023, p4507 Journal Article, 2023

Pablo Vidal-Cortés, Prof. Ignacio martin-loeches, Alejandro Rodríguez, German Bou, Rafael Canton, EMILIO DIAZ, Carmen De la Fuente, Julián Torre-Cisneros, Francisco Xavier Nuvials, Miguel Salavert Lleti, Gerardo Aguilar, Mercedes Nieto, Paula Ramírez, Marcio Borges, Cruz Soriano, Ricard Ferrer, Emilio Maseda, Rafael Zaragoza, Current Positioning against Severe Infections Due to Klebsiella pneumoniae in Hospitalized Adults, Antibiotics, 11, (9), 2022, p1160 Journal Article, 2022

Rachael Cusack, Marc Leone, Alejandro H. Rodriguez, Prof. Ignacio martin-loeches, Endothelial Damage and the Microcirculation in Critical Illness, Biomedicines, 10, (12), 2022, p3150 Journal Article, 2022

Ines Lakbar, Louis Delamarre, Fanny Curtel, Gary DUCLOS, Karine Bezulier, Ines Gragueb-Chatti, Prof. Ignacio martin-loeches, Jean-Marie Forel, Marc Leone, Antimicrobial Stewardship during COVID-19 Outbreak: A Retrospective Analysis of Antibiotic Prescriptions in the ICU across COVID-19 Waves, Antibiotics, 11, (11), 2022, p1517 Journal Article, 2022

Liam Townsend, Prof. Ignacio martin-loeches, Invasive Aspergillosis in the Intensive Care Unit, Diagnostics, 12, (11), 2022, p2712 Journal Article, 2022

Jan J. De Waele, Massimo Girardis, Ignacio Martin-Loeches, Source control in the management of sepsis and septic shock, Intensive Care Medicine, 48, (12), 2022, p1799-1802 Journal Article, 2022

Sean Boyd, Saad Nseir, Alejandro Rodriguez, Ignacio Martin-Loeches, Ventilator-associated pneumonia in critically ill patients with COVID-19 infection: a narrative review, ERJ Open Research, 8, (3), 2022, p00046-2022 Journal Article, 2022

Ignacio Martin-Loeches, Therapeutic drug monitoring (TDM) in real-time: a need for the present future, Expert Review of Anti-infective Therapy, 20, (10), 2022, p1245-1247 Journal Article, 2022

Rachael Cusack, Susan O'Neill, Prof. Ignacio martin-loeches, Effects of Fluids on the Sublingual Microcirculation in Sepsis, Journal of Clinical Medicine, 11, (24), 2022, p7277 Journal Article, 2022

Mokart, Djamel and Darmon, Michael and Schellongowski, Peter and Pickkers, Peter and Soares, Marcio and Rello, Jordi and Bauer, Philippe R and van de Louw, Andry and Lemiale, Virginie and Taccone, Fabio Silvio and Martin-Loeches, Ignacio and Salluh, Jorge and Rusinova, Katerina and Mehta, Sangeeta and Antonelli, Massimo and Kouatchet, Achille and Barratt-Due, Andreas and Valkonen, Miia and Landburg, Precious Pearl and Bukan, Ramin Brandt and PÚne, Frédéric and Metaxa, Victoria and Burghi, Gaston and Saillard, Colombe and Nielsen, Lene B and Canet, Emmanuel and Bisbal, Magali and Azoulay, Elie and {Efraim investigators and the Nine-I study group, Acute respiratory failure in immunocompromised patients: outcome and clinical features according to neutropenia status, Annals of intensive care, 10, (1), 2020, p146 Journal Article, 2020 DOI

Roberts, Jason A and Joynt, Gavin and Lee, Anna and Choi, Gordon and Bellomo, Rinaldo and Kanji, Salmaan and Mudaliar, M Yugan and Peake, Sandra L and Stephens, Dianne and Taccone, Fabio Silvio and Ulldemolins, Marta and Valkonen, Miia Maaria and Agbeve, Julius and Baptista, João P and Bekos, Vasileios and Boidin, Clement and Brinkmann, Alexander and Buizen, Luke and Castro, Pedro and Cole, C Louise and Creteur, Jacques and De Waele, Jan J and Deans, Renae and Eastwood, Glenn M and Escobar, Leslie and Gomersall, Charles and Gresham, Rebecca and Jamal, Janattul Ain and Kluge, Stefan and König, Christina and Koulouras, Vasilios P and Lassig-Smith, Melissa and Laterre, Pierre-Francois and Lei, Katie and Leung, Patricia and Lefrant, Jean-Yves and Llauradó-Serra, Mireia and Martin-Loeches, Ignacio and Mat Nor, Mohd Basri and Ostermann, Marlies and Parker, Suzanne L and Rello, Jordi and Roberts, Darren M and Roberts, Michael S and Richards, Brent and Rodríguez, Alejandro and Roehr, Anka C and Roger, Claire and Seoane, Leonardo and Sinnollareddy, Mahipal and Sousa, Eduardo and Soy, Dolors and Spring, Anna and Starr, Therese and Thomas, Jane and Turnidge, John and Wallis, Steven C and Williams, Tricia and Wittebole, Xavier and Zikou, Xanthi T and Paul, Sanjoy and Lipman, Jeffrey, The effect of renal replacement therapy and antibiotic dose on antibiotic concentrations in critically ill patients: Data from the multinational SMARRT Study, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020 Journal Article, 2020 DOI

, Antibiotic prophylaxis in the ICU: to be or not to be administered for patients undergoing procedures?, Intensive care medicine, 2020 Journal Article, 2020 DOI

Verweij, Paul E and Rijnders, Bart J A and BrÃŒggemann, Roger J M and Azoulay, Elie and Bassetti, Matteo and Blot, Stijn and Calandra, Thierry and Clancy, Cornelius J and Cornely, Oliver A and Chiller, Tom and Depuydt, Pieter and Giacobbe, Daniele Roberto and Janssen, Nico A F and Kullberg, Bart-Jan and Lagrou, Katrien and Lass-Flörl, Cornelia and Lewis, Russell E and Liu, Peter Wei-Lun and Lortholary, Olivier and Maertens, Johan and Martin-Loeches, Ignacio and Nguyen, M Hong and Patterson, Thomas F and Rogers, Thomas R and Schouten, Jeroen A and Spriet, Isabel and Vanderbeke, Lore and Wauters, Joost and van de Veerdonk, Frank L, Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion, Intensive care medicine, 46, (8), 2020, p1524â€"1535 Journal Article, 2020 DOI

Liam Townsend, Adam H Dyer, Karen Jones, Jean Dunne, Rachel Kiersey, Fiona Gaffney, Laura O'Connor, Aoife Mooney, Deirdre Leavy, Katie Ridge, Catherine King, Fionnuala Cox, Kate O'Brien, Joanne Dowds, Jamie Sugrue, David Hopkins, Patricia Byrne, Tara Kingston, Cliona Ni Cheallaigh, Parthiban Nadarajan, Anne Marie McLaughlin, Nollaig M Bourke, Colm Bergin, Cliona O'Farrelly, Ciaran Bannan, Niall Conlon, Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection, PloS One, 2020 Journal Article, 2020

Hodalova S, Moore S, Dowds J ,Murphy N, Martin-Loeches I, Broderick J. , Feasibility of Telephone Follow-Up after Critical Care Discharge, Medical Sciences , 8(1), (16), 2020 Journal Article, 2020 DOI URL TARA - Full Text

Munshi, Laveena and Darmon, Michael and Soares, Marcio and Pickkers, Peter and Bauer, Philippe and Meert, Anne-Pascale and Martin-Loeches, Ignacio and Staudinger, Thomas and Pene, Frederic and Antonelli, Massimo and Barratt-Due, Andreas and Demoule, Alexandre and Metaxa, Victoria and Lemiale, Virginie and Taccone, Fabio and Mokart, Djamel and Azoulay, Elie and Mehta, Sangeeta, Acute Respiratory Failure Outcomes in Patients with Hematologic Malignancies and Hematopoietic Cell Transplant: A Secondary Analysis of the EFRAIM Study, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020 Journal Article, 2020 DOI

Lopez, René and Rello, Jordi and Taccone, Fabio Silvio and Salem, Omar Ben Hadj and Bauer, Philippe R and Séguin, Amélie and van de Louw, Andry and Metaxa, Victoria and Klouche, Kada and Martin Loeches, Ignacio and Montini, Luca and Mehta, Sangeeta and Bruneel, Fabrice and Lisboa, T and Viana, William and Pickkers, Peter and Russell, Lene and Rusinova, Katerina and Kouatchet, Achille and Barbier, François and Mokart, Djamel and Azoulay, Elie and Darmon, Michael, Aminoglycosides in Immunocompromised Critically Ill Patients With Bacterial Pneumonia and Septic Shock: A Post-Hoc Analysis of a Prospective Multicenter Multinational Cohort, Shock (Augusta, Ga.), 54, (6), 2020, p731â€"737 Journal Article, 2020 DOI

Cantan, B and Martin-Loeches, I, From the macro to the micro. Diagnosis at first glance, Medicina intensiva, 2020 Journal Article, 2020 DOI

Torres, Antoni and Martin-Loeches, Ignacio, Invasive Pulmonary Aspergillosis in Ventilator-associated Pneumonia: The Hidden Enemy?, American journal of respiratory and critical care medicine, 202, (8), 2020, p1071â€"1073 Journal Article, 2020 DOI

Bassetti M, Giacobbe DR, Grecchi C, Rebuffi C, Zuccaro V, Scudeller L, =FUNDICU investigators, Performance of existing definitions and tests for the diagnosis of invasive aspergillosis in critically ill, adult patients: A systematic review with qualitative evidence synthesis , The Journal of infection , 81 , (1 ), 2020, p131 - 146 Journal Article, 2020 DOI URL

OÊŒSullivan, Shane and Torres, Antoni and Rodriguez, Alejandro and Martin-Loeches, Ignacio, Influenza management with new therapies, Current opinion in pulmonary medicine, 26, (3), 2020, p215â€"221 Journal Article, 2020 DOI

Martin-Loeches Ignacio, Darmon Michael, Demoule Alexandre, Antonelli Massimo, Schellongowski Peter, Pickkers Peter, Soares Marcio, Rello Jordi, Bauer Philippe, van de Louw Andry, Lemiale Virgine, Grimaldi David, Balik Martin, Mehta Sangeeta, Kouatchet Ac, Barratt-Due Andreas, Valkonen Miia, Reignier Jean, Metaxa Victoria, Moreau Anne Sophie, Burghi Gaston, Mokart Djamel, Azoulay Elie, =Efraim investigators and the Nine-I study group, ICU-acquired pneumonia in immunosuppressed patients with acute hypoxemic respiratory failure: A post-hoc analysis of a prospective international cohort study , Journal of critical care , 2020 Journal Article, 2020 DOI URL

Azoulay Elie, Bauer Philippe R, Mariotte Eric, Russell Lene, Knoebl Paul, Martin-Loeches Ignacio, PÚne Frédéric, Puxty Kathryn, Povoa Pedro, Barratt-Due Andreas, Garnacho-Montero Jose, Wendon Julia, Munshi Laveena, Benoit Dominique, von Bergwelt-Baildon Michael, Maggiorini Marco, Coppo Paul, Cataland Spero, Veyradier AgnÚs, Van de Louw Andry, =Nine-i Investigators, Correction to: Expert statement on the ICU management of patients with thrombotic thrombocytopenic purpura , Intensive care medicine , 46 , (3 ), 2020, p570 - 571 Journal Article, 2020 DOI URL

Garnacho-Montero, José and Martín-Loeches, Ignacio, Clinical management of sepsis can be improved by artificial intelligence: no, Intensive care medicine, 46, (2), 2020, p378â€"380 Journal Article, 2020 DOI

Bein Thomas, Vargiolu Alessia, =ICM Editorial Board, Ensuring editorial continuity and quality of science during the COVID-19 storm: the ICM experience , Intensive care medicine , 46 , (10 ), 2020, p1918 - 1920 Journal Article, 2020 URL DOI

McEnery, Tom and Martin-Loeches, Ignacio, Predicting ventilator-associated pneumonia, Annals of translational medicine, 8, (11), 2020, p670 Journal Article, 2020 DOI

Logan, C and Martin-Loeches, I and Bicanic, T, Invasive candidiasis in critical care: challenges and future directions, Intensive care medicine, 46, (11), 2020, p2001â€"2014 Journal Article, 2020 DOI

Deutschman Clifford S, Hellman Judith, Roca Ricard Ferrer, De Backer Daniel, Coopersmith Craig M, =Research Committee of the Surviving Sepsis Campaign, The surviving sepsis campaign: basic/translational science research priorities , Intensive care medicine experimental , 8 , (1 ), 2020, p31 - Journal Article, 2020 URL DOI

Wong Adrian, Galarza Laura, Forni Lui, De Backer Daniel, Slama Michael, Cholley Bernard, Mayo Paul, McLean Anthony, Vieillard-Baron Antoine, Lichtenstein Daniel, Volpicelli Giovanni, Arntfield Robert, Martin-Loeches Ignacio, Istrate Gizella Melania, Duška František, =ESICM Critical Care Ultrasound Group, Recommendations for core critical care ultrasound competencies as a part of specialist training in multidisciplinary intensive care: a framework proposed by the European Society of Intensive Care Medicine (ESICM) , Critical care (London, England) , 24 , (1 ), 2020, p393 - Journal Article, 2020 DOI URL

Luyt, Charles-Edouard and Bouadma, Lila and Morris, Andrew Conway and Dhanani, Jayesh A and Kollef, Marin and Lipman, Jeffrey and Martin-Loeches, Ignacio and Nseir, Saad and Ranzani, Otavio T and Roquilly, Antoine and Schmidt, Matthieu and Torres, Antoni and Timsit, Jean-François, Pulmonary infections complicating ARDS, Intensive care medicine, 2020 Journal Article, 2020 DOI

Guidet Bertrand, de Lange Dylan W, Boumendil Ariane, Leaver Susannah, Watson Ximena, Boulanger Carol, Szczeklik Wojciech, Artigas Antonio, Morandi Alessandro, Andersen Finn, Zafeiridis Tilemachos, Jung Christian, Moreno Rui, Walther Sten, Oeyen Sandra, Schefold Joerg C, Cecconi Maurizio, Marsh Brian, Joannidis Michael, Nalapko Yuriy, Elhadi Muhammed, FjÞlner Jesper, Flaatten Hans, =VIP2 study group, The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study , Intensive care medicine , 46 , (1 ), 2020, p57 - 69 Journal Article, 2020 URL DOI

Villafuerte David, Aliberti Stefano, Soni Nilam J, Faverio Paola, Marcos Pedro J, Wunderink Richard G, Rodriguez Alejandro, Sibila Oriol, Sanz Francisco, Martin-Loeches Ignacio, Menzella Francesco, Reyes Luis F, Jankovic Mateja, Spielmanns Marc, Restrepo Marcos I, =GLIMP Investigators, Prevalence and risk factors for Enterobacteriaceae in patients hospitalized with community-acquired pneumonia , Respirology (Carlton, Vic.) , 25 , (5 ), 2020, p543 - 551 Journal Article, 2020 DOI URL

Póvoa Pedro, Coelho Luís, Nora David, Martin-Loeches Ignacio, Antifungal use in the surgical ICU patient , Current opinion in anaesthesiology , 33 , (2 ), 2020, p131 - 138 Journal Article, 2020 URL DOI

Lakbar, Ines and De Waele, Jan J and Tabah, Alexis and Einav, Sharon and Martin-Loeches, Ignacio and Leone, Marc, Antimicrobial De-Escalation in the ICU: From Recommendations to Level of Evidence, Advances in therapy, 37, (7), 2020, p3083â€"3096 Journal Article, 2020 DOI

Martin-Loeches, Ignacio and Bisanti, Alessandra and Diaz, Emili and Rodriguez, Alejandro, Ceftolozane and tazobactam for the treatment of hospital acquired pneumonia, Expert review of anti-infective therapy, 18, (12), 2020, p1177â€"1185 Journal Article, 2020 DOI

Fogarty, Helen, Townsend, Liam, Ni Cheallaigh, Cliona, Bergin, Colm, Martin"Loeches, Ignacio, Browne, Paul, Bacon, Christopher L., Gaule, Richard, Gillett, Alexander, Byrne, Mary, Ryan, Kevin, O"Connell, Niamh, O"Sullivan, Jamie M., Conlon, Niall, O'Donnell, James S., COVID19 coagulopathy in Caucasian patients, British Journal of Haematology, 189, (6), 2020, p1044-1049 Journal Article, 2020 DOI

Tankel James, Zimmerman Frederic, De Jong Audrey, Martin-Loeches Ignacio, Einav Sharon, From the ICU to the operating room: how to manage the patient? , Current opinion in anaesthesiology , 33 , (2 ), 2020, p139 - 145 Journal Article, 2020 URL DOI

WHO Working Group on the Clinical Characterisation and Management of COVID-19 infection, A minimal common outcome measure set for COVID-19 clinical research, The Lancet. Infectious diseases, 20, (8), 2020, pe192â€"e197 Journal Article, 2020 DOI

Vallecoccia Maria Sole, Dominedò Cristina, Cutuli Salvatore Lucio, Martin-Loeches Ignacio, Torres Antoni, De Pascale Gennaro, Is ventilated hospital-acquired pneumonia a worse entity than ventilator-associated pneumonia? , European respiratory review : an official journal of the European Respiratory Society , 29 , (157 ), 2020 Journal Article, 2020 DOI URL

Vincent Jean-Louis, Sakr Yasser, Singer Mervyn, Martin-Loeches Ignacio, Machado Flavia R, Marshall John C, Finfer Simon, Pelosi Paolo, Brazzi Luca, Aditianingsih Dita, Timsit Jean-François, Du Bin, Wittebole Xavier, Máca Jan, Kannan Santhana, Gorordo-Delsol Luis A, De Waele Jan J, Mehta Yatin, Bonten Marc J M, Khanna Ashish K, Kollef Marin, Human Mariesa, Angus Derek C, =EPIC III Investigators, Prevalence and Outcomes of Infection Among Patients in Intensive Care Units in 2017 , JAMA , 323 , (15 ), 2020, p1478 - 1487 Journal Article, 2020 DOI URL

, Lower Respiratory Tract Infection and Short-Term Outcome in Patients With Acute Respiratory Distress Syndrome, Journal of intensive care medicine, 2020 Journal Article, 2020 DOI

Antonelli Massimo, Martin-Loeches Ignacio, Dimopoulos George, Gasbarrini Antonio, Vallecoccia Maria Sole, Clostridioides difficile (formerly Clostridium difficile) infection in the critically ill: an expert statement , Intensive care medicine , 46 , (2 ), 2020, p215 - 224 Journal Article, 2020 DOI URL

Gaudet Alexandre, Martin-Loeches Ignacio, Povoa Pedro, Rodriguez Alejandro, Salluh Jorge, Duhamel Alain, Nseir Saad, =TAVeM study group, Accuracy of the clinical pulmonary infection score to differentiate ventilator-associated tracheobronchitis from ventilator-associated pneumonia , Annals of intensive care , 10 , (1 ), 2020, p101 - Journal Article, 2020 DOI URL

Rouzé Anahita, Boddaert Pauline, Martin-Loeches Ignacio, Povoa Pedro, Rodriguez Alejandro, Ramdane Nassima, Salluh Jorge, Houard Marion, Nseir Saad, Impact of Chronic Obstructive Pulmonary Disease on Incidence, Microbiology and Outcome of Ventilator-Associated Lower Respiratory Tract Infections , Microorganisms , 8 , (2 ), 2020 Journal Article, 2020 DOI URL

Vincent Jean-Louis, Ferguson Andrew, Pickkers Peter, Jakob Stephan M, Jaschinski Ulrich, Almekhlafi Ghaleb A, Leone Marc, Mokhtari Majid, Fontes Luis E, Bauer Philippe R, Sakr Yasser, =ICON Investigators, The clinical relevance of oliguria in the critically ill patient: analysis of a large observational database , Critical care (London, England) , 24 , (1 ), 2020, p171 - Journal Article, 2020 DOI URL

Blake, Alan and Collins, Daniel and O'Connor, Enda and Bergin, Colm and McLaughlin, Anne Marie and Martin-Loeches, Ignacio, Clinical and biochemical characteristics of patients admitted to ICU with SARS-CoV-2, Medicina intensiva, 2020 Journal Article, 2020 DOI

De Bus, Liesbet and Depuydt, Pieter and Steen, Johan and Dhaese, Sofie and De Smet, Ken and Tabah, Alexis and Akova, Murat and Cotta, Menino Osbert and De Pascale, Gennaro and Dimopoulos, George and Fujitani, Shigeki and Garnacho-Montero, Jose and Leone, Marc and Lipman, Jeffrey and Ostermann, Marlies and Paiva, José-Artur and Schouten, Jeroen and Sjövall, Fredrik and Timsit, Jean-François and Roberts, Jason A and Zahar, Jean-Ralph and Zand, Farid and Zirpe, Kapil and De Waele, Jan J and {DIANA study group, Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study, Intensive care medicine, 46, (7), 2020, p1404â€"1417 Journal Article, 2020 DOI

Waqas S, Dunne K, Talento AF, Wilson G, Martin-Loeches I, Keane J, Rogers TR., Prospective observational study of respiratory Aspergillus colonization or disease in patients with various stages of chronic obstructive pulmonary disease utilizing culture versus nonculture techniques., Medical mycology, 2020 Journal Article, 2020 DOI

Gramegna Andrea, Sotgiu Giovanni, Di Pasquale Marta, Radovanovic Dejan, Terraneo Silvia, Reyes Luis F, Vendrell Ester, Neves Joao, Menzella Francesco, Blasi Francesco, Aliberti Stefano, Restrepo Marcos I, =GLIMP Study Group, Correction to: Atypical pathogens in hospitalized patients with community-acquired pneumonia: a worldwide perspective , BMC infectious diseases , 20 , (1 ), 2020, p748 - Journal Article, 2020 DOI URL

Saied Wafa Ibn, Martin-Loeches Ignacio, Timsit Jean-François, What is new in non-ventilated ICU-acquired pneumonia? , Intensive care medicine , 46 , (3 ), 2020, p488 - 491 Journal Article, 2020 URL DOI

Marin-Corral, Judith and Pascual-Guardia, Sergi and Francesco, Amati and Aliberti, Stefano and Masclans, Joan R and Soni, Nilam and Rodriguez, Alejandro and Sibila, Oriol and Sanz, Francisco and Sotgiu, Giovanni and Anzueto, Antonio and Dimakou, Katerina and Petrino, Roberta and van de Garde, Ewoudt and Restrepo, Marcos I and {GLIMP investigators, Aspiration Risk Factors, Microbiology, and Empiric Antibiotics for Patients Hospitalized With Community-Acquired Pneumonia, Chest, 2020 Journal Article, 2020 DOI

Martin-Loeches Ignacio, Current Concepts in Community and Ventilator Associated Lower Respiratory Tract Infections in ICU Patients , Antibiotics (Basel, Switzerland) , 9 , (7 ), 2020 Journal Article, 2020 DOI URL

Martin-Loeches Ignacio, Dickson Robert, Torres Antoni, Hanberger HÃ¥kan, Lipman Jeffrey, Antonelli Massimo, de Pascale Gennaro, Bozza Fernando, Vincent Jean Louis, Murthy Srinivas, Bauer Michael, Marshall John, Cilloniz Catia, Bos Lieuwe D, The importance of airway and lung microbiome in the critically ill , Critical care (London, England) , 24 , (1 ), 2020, p537 - Journal Article, 2020 DOI URL

Rello, Jordi and Belliato, Mirko and Dimopoulos, Meletios-Athanasios and Giamarellos-Bourboulis, Evangelos J and Jaksic, Vladimir and Martin-Loeches, Ignacio and Mporas, Iosif and Pelosi, Paolo and Poulakou, Garyphallia and Pournaras, Spyridon and Tamae-Kakazu, Maximiliano and Timsit, Jean-François and Waterer, Grant and Tejada, Sofia and Dimopoulos, George, Update in COVID-19 in the intensive care unit from the 2020 HELLENIC Athens International symposium, Anaesthesia, critical care & pain medicine, 2020 Journal Article, 2020 DOI

Atterton, Ben and Paulino, Maria Carolina and Povoa, Pedro and Martin-Loeches, Ignacio, Sepsis Associated Delirium, Medicina (Kaunas, Lithuania), 56, (5), 2020 Journal Article, 2020 DOI

Demoule, Alexandre and Antonelli, Massimo and Schellongowski, Peter and Pickkers, Peter and Soares, Marcio and Meyhoff, Tine and Rello, Jordi and Bauer, Philippe R and van de Louw, Andry and Lemiale, Virgine and Grimaldi, David and Martin-Loeches, Ignacio and Balik, Martin and Mehta, Sangeeta and Kouatchet, Achille and Barratt-Due, Andreas and Valkonen, Miia and Reignier, Jean and Metaxa, Victoria and Moreau, Anne-Sophie and Burghi, Gaston and Mokart, Djamel and Mayaux, Julien and Darmon, Michael and Azoulay, Elie and {EFRAIM Investigators, Respiratory Mechanics and Outcomes in Immunocompromised Patients With ARDS: A Secondary Analysis of the EFRAIM Study, Chest, 158, (5), 2020, p1947â€"1957 Journal Article, 2020 DOI

Zaragoza Rafael, Vidal-Cortés Pablo, Aguilar Gerardo, Borges Marcio, Diaz Emili, Ferrer Ricard, Maseda Emilio, Nieto Mercedes, Nuvials Francisco Xavier, Ramirez Paula, Rodriguez Alejandro, Soriano Cruz, Veganzones Javier, Martín-Loeches Ignacio, Update of the treatment of nosocomial pneumonia in the ICU , Critical care (London, England) , 24 , (1 ), 2020, p383 - Journal Article, 2020 URL DOI

, Conventional amphotericin B must be avoided in Candida infections, Intensive care medicine, 2020 Journal Article, 2020 DOI

Martin-Loeches, Ignacio and Povoa, Pedro and Nseir, Saad, A way towards ventilator-associated lower respiratory tract infection research, Intensive care medicine, 46, (7), 2020, p1504â€"1505 Journal Article, 2020 DOI

Fogarty, Helen, Townsend, Liam, Ni Cheallaigh, Cliona, Bergin, Colm, Martin"Loeches, Ignacio, Browne, Paul, Bacon, Christopher L., Gaule, Richard, Gillett, Alexander, Byrne, Mary, Ryan, Kevin, O'Connell, Niamh, O'Sullivan, Jamie M., Conlon, Niall, O'Donnell, James S., More on COVID"19 coagulopathy in Caucasian patients, British Journal of Haematology, 189, (6), 2020, p1060-1061 Journal Article, 2020 DOI

Torres Antoni, Barberán José, Ceccato Adrian, Martin-Loeches Ignacio, Ferrer Miguel, Menéndez Rosario, Rigau David, Hospital-Acquired Pneumonia. Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) Guidelines. 2019 Update , Archivos de bronconeumologia , 56 Suppl 1 , 2020, p11 - 19 Journal Article, 2020 DOI URL

, Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project, Critical care (London, England), 2019 Journal Article, 2019 DOI

Kollef Marin H, NovÃ¡Ä ek Martin, Kivistik à lo, Réa-Neto à lvaro, Shime Nobuaki, Martin-Loeches Ignacio, Timsit Jean-François, Wunderink Richard G, Bruno Christopher J, Huntington Jennifer A, Lin Gina, Yu Brian, Butterton Joan R, Rhee Elizabeth G, Ceftolozane-tazobactam versus meropenem for treatment of nosocomial pneumonia (ASPECT-NP): a randomised, controlled, double-blind, phase 3, non-inferiority trial , The Lancet. Infectious diseases , 19 , (12 ), 2019, p1299 - 1311 Journal Article, 2019 DOI URL

Meyfroidt G, Gunst J, Martin-Loeches I, Smith M, Robba C, Taccone FS, Citerio G, Management of the brain-dead donor in the ICU: general and specific therapy to improve transplantable organ quality., Intensive care medicine, 2019 Journal Article, 2019

Neto Ary Serpa, Schultz Marcus J., Festic Emir, Adhikari Neill K. J., Dondorp Arjen M., Pattnaik Rajyabardhan, Pisani Luigi, Povoa Pedro, Martin-Loeches Ignacio, Thwaites C. Louise, Ventilatory Support of Patients with Sepsis or Septic Shock in Resource-Limited Settings , 2019, - Miscellaneous, 2019 URL

Martin-Loeches I, Guia MC, Vallecoccia MS, Suarez D, Ibarz M, Irazabal M, Ferrer R, Artigas A, Risk factors for mortality in elderly and very elderly critically ill patients with sepsis: a prospective, observational, multicenter cohort study., Annals of intensive care, 2019 Journal Article, 2019

Rubio Ignacio, Osuchowski Marcin F, Shankar-Hari Manu, Skirecki Tomasz, Winkler Martin Sebastian, Lachmann Gunnar, La Rosée Paul, Monneret Guillaume, Venet Fabienne, Bauer Michael, Brunkhorst Frank M, Kox Matthijs, Cavaillon Jean-Marc, Uhle Florian, Weigand Markus A, Flohé Stefanie B, Wiersinga W Joost, Martin-Fernandez Marta, Almansa Raquel, Martin-Loeches Ignacio, Torres Antoni, Giamarellos-Bourboulis Evangelos J, Girardis Massimo, Cossarizza Andrea, Netea Mihai G, van der Poll Tom, Scherag André, Meisel Christian, Schefold Joerg C, Bermejo-Martín Jesús F, Current gaps in sepsis immunology: new opportunities for translational research , The Lancet. Infectious diseases , 19 , (12 ), 2019, pe422-e436 - Journal Article, 2019 DOI URL

, Management of donation after brain death (DBD) in the ICU: the potential donor is identified, what's next?, Intensive care medicine, 2019 Journal Article, 2019 DOI

, Clinical controversies in abdominal sepsis. Insights for critical care settings, Journal of critical care, 2019 Journal Article, 2019 DOI

, MRI Assessment of Global and Regional Diaphragmatic Motion in Critically Ill Patients Following Prolonged Ventilator Weaning, Medical sciences (Basel, Switzerland), 2019 Journal Article, 2019 DOI

Cortegiani Andrea, Misseri Giovanni, Ippolito Mariachiara, Bassetti Matteo, Giarratano Antonino, Martin-Loeches Ignacio, Einav Sharon, Correction to: Procalcitonin levels in candidemia versus bacteremia: a systematic review , Critical care (London, England) , 23 , (1 ), 2019, p322 - Journal Article, 2019 URL DOI

Weiss Emmanuel, Zahar Jean-Ralph, Alder Jeff, Asehnoune Karim, Bassetti Matteo, Bonten Marc J M, Chastre Jean, De Waele Jan, Dimopoulos George, Eggimann Philippe, Engelhardt Marc, Ewig Santiago, Kollef Marin, Lipman Jeffrey, Luna Carlos, Martin-Loeches Ignacio, Pagani Leonardo, Palmer Lucy B, Papazian Laurent, Poulakou Garyphallia, Prokocimer Philippe, Rello Jordi, Rex John H, Shorr Andrew F, Talbot George H, Thamlikitkul Visanu, Torres Antoni, Wunderink Richard G, Timsit Jean-François, Elaboration of Consensus Clinical Endpoints to Evaluate Antimicrobial Treatment Efficacy in Future Hospital-acquired/Ventilator-associated Bacterial Pneumonia Clinical Trials , Clinical infectious diseases : an official publication of the Infectious Diseases Society of America , 69 , (11 ), 2019, p1912 - 1918 Journal Article, 2019 URL DOI

Kwizera Arthur, Adhikari Neill K. J., Angus Derek C., Dondorp Arjen M., DÃŒnser Martin W., Festic Emir, Haniffa Rashan, Kissoon Niranjan, Martin-Loeches Ignacio, Lundeg Ganbold, Recognition of Sepsis in Resource-Limited Settings , 2019, - Miscellaneous, 2019 URL

Martin-Loeches Ignacio, Guia Maria Consuelo, Vallecoccia Maria Sole, Suarez David, Ibarz Mercedes, Irazabal Marian, Ferrer Ricard, Artigas Antonio, Correction to: Risk factors for mortality in elderly and very elderly critically ill patients with sepsis: a prospective, observational, multicenter cohort study , Annals of intensive care , 9 , (1 ), 2019, p36 - Journal Article, 2019 DOI URL

, Candida Prophylaxis and Treatment in Critically Ill Patients after Abdominal Surgery: A Survey of Practice, Surgical infections, 2019 Journal Article, 2019 DOI

Martin-Loeches I, Torres A, ENIRRIs Clinical Research Collaboration, The European Network for ICU-Related Respiratory Infections (ENIRRIs) ERS Clinical Research Collaboration., The European respiratory journal, 2019 Journal Article, 2019

, Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) With Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients: A Randomized Clinical Trial, JAMA, 2019 Journal Article, 2019 DOI

, Soluble urokinase plasminogen activator receptor for the prediction of ventilator-associated pneumonia, ERJ open research, 2019 Journal Article, 2019 DOI

Martin-Loeches Ignacio, Torres Antoni, Povoa Pedro, Zampieri Fernando G, Salluh Jorge, Nseir Saad, Ferrer Miquel, Rodriguez Alejandro, =TAVeM study Group, The association of cardiovascular failure with treatment for ventilator-associated lower respiratory tract infection , Intensive care medicine , 45 , (12 ), 2019, p1753 - 1762 Journal Article, 2019 URL DOI

, Procalcitonin levels in candidemia versus bacteremia: a systematic review, Critical care (London, England), 2019 Journal Article, 2019 DOI

Rouzé A, Martin-Loeches I, Nseir S, Improved Endotracheal Tubes for Prevention of Ventilator-Associated Pneumonia: Better Than Silver and Gold?, Respiratory care, 2019 Journal Article, 2019

Di Pasquale Marta Francesca, Sotgiu Giovanni, Gramegna Andrea, Radovanovic Dejan, Terraneo Silvia, Reyes Luis F, Rupp Jan, González Del Castillo Juan, Blasi Francesco, Aliberti Stefano, Restrepo Marcos I, =GLIMP Investigators, Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients , Clinical infectious diseases : an official publication of the Infectious Diseases Society of America , 68 , (9 ), 2019, p1482 - 1493 Journal Article, 2019 DOI URL

Martin-Loeches Ignacio, Lemiale Virginie, Geoghegan Pierce, McMahon Mary Aisling, Pickkers Peter, Soares Marcio, Perner Anders, Meyhoff Tine Sylvest, Bukan Ramin Brandt, Rello Jordi, Bauer Philippe R, van de Louw Andry, Taccone Fabio Silvio, Salluh Jorge, Hemelaar Pleun, Schellongowski Peter, Rusinova Katerina, Terzi Nicolas, Mehta Sangeeta, Antonelli Massimo, Kouatchet Achille, Klepstad Pål, Valkonen Miia, Landburg Precious Pearl, Barratt-Due Andreas, Bruneel Fabrice, PÚne Frédéric, Metaxa Victoria, Moreau Anne Sophie, Souppart Virginie, Burghi Gaston, Girault Christophe, Silva Ulysses V A, Montini Luca, Barbier Francois, Nielsen Lene B, Gaborit Benjamin, Mokart Djamel, Chevret Sylvie, Azoulay Elie, =Efraim investigators and the Nine-I study group, Influenza and associated co-infections in critically ill immunosuppressed patients , Critical care (London, England) , 23 , (1 ), 2019, p152 - Journal Article, 2019 URL DOI

, 2226. Impact of Prior and Concomitant Antibacterial Therapy on Outcomes in the ASPECT-NP Randomized, Controlled Trial of Ceftolozane/Tazobactam (C/T) vs. Meropenem (MEM) in Patients with Ventilated Nosocomial Pneumonia (NP), Open forum infectious diseases, 2019 Journal Article, 2019

, Source control and intra-abdominal infections: Still many questions and only limited answers, Journal of critical care, 2019 Journal Article, 2019 DOI

Keane Sean, Martin-Loeches Ignacio, Host-pathogen interaction during mechanical ventilation: systemic or compartmentalized response? , Critical care (London, England) , 23 , (Suppl 1 ), 2019, p134 - Journal Article, 2019 DOI URL

Cantan Ben, Luyt Charles-Edouard, Martin-Loeches Ignacio, Influenza Infections and Emergent Viral Infections in Intensive Care Unit , Seminars in respiratory and critical care medicine , 40 , (4 ), 2019, p488 - 497 Journal Article, 2019 DOI URL

Ferrer Miquel, Sequeira Telma, Cilloniz Catia, Dominedo Cristina, Bassi Gianluigi Li, Martin-Loeches Ignacio, Torres Antoni, Ventilator-Associated Pneumonia and PaO2/FIO2 Diagnostic Accuracy: Changing the Paradigm? , Journal of clinical medicine , 8 , (8 ), 2019 Journal Article, 2019 DOI URL

, Early Sedation with Dexmedetomidine in Critically Ill Patients, The New England journal of medicine, 2019 Journal Article, 2019 DOI

Weiss E, Zahar JR, Alder J, Asehnoune K, Bassetti M, Bonten MJM, Chastre J, De Waele J, Dimopoulos G, Eggimann P, Engelhardt M, Ewig S, Kollef M, Timsit JF, Elaboration of consensus clinical endpoints to evaluate antimicrobial treatment efficacy in future HABP/VABP clinical trials., Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019 Journal Article, 2019

, Expert statement on the ICU management of patients with thrombotic thrombocytopenic purpura, Intensive care medicine, 2019 Journal Article, 2019 DOI

, Diagnosis and outcome of acute respiratory failure in immunocompromised patients after bronchoscopy, The European respiratory journal, 2019 Journal Article, 2019 DOI

Marini John J, DeBacker Daniel, Gattinoni Luciano, Ince Can, Martin-Loeches Ignacio, Singer Pierre, Singer Mervyn, Westphal Martin, Vincent Jean-Louis, Thinking forward: promising but unproven ideas for future intensive care , Critical care (London, England) , 23 , (Suppl 1 ), 2019, p197 - Journal Article, 2019 DOI URL

Torres A, Chalmers JD, Dela Cruz CS, Dominedò C, Kollef M, Martin-Loeches I, Niederman M, Wunderink RG, Challenges in severe community-acquired pneumonia: a point-of-view review., Intensive care medicine, 2019 Journal Article, 2019

, Severe community-acquired pneumonia: current management and future therapeutic alternatives, Expert review of anti-infective therapy, 2018 Journal Article, 2018 DOI

De Pascale G, Bello G, Dell'Anna AM, Montini L, Antonelli M, Moreno G, Rodriguez A, Martin-Loeches I, Steroids and severe pneumonia. Ready for the winter? Discussion on "Corticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study"., Intensive care medicine, 2018 Journal Article, 2018

Ceccato A, Cilloniz C, Martin-Loeches I, Ranzani OT, Gabarrus A, Bueno L, Garcia-Vidal C, Ferrer M, Niederman MS, Torres A, Effect of Combined ß-Lactam/Macrolide Therapy on Mortality According to the Microbial Etiology and Inflammatory Status of Patients With Community-Acquired Pneumonia., Chest, 2018 Journal Article, 2018

, Optimal duration of antibiotic treatment in Gram-negative infections, Current opinion in infectious diseases, 2018 Journal Article, 2018 DOI

Bassetti M, Scudeller L, Giacobbe DR, Lamoth F, Righi E, Zuccaro V, Grecchi C, Rebuffi C, Akova M, Alastruey-Izquierdo A, Arikan-Akdagli S, Mycoses Study Group Education and Research Consortium (MSGERC), Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project., Mycoses, 2018 Journal Article, 2018

Keane S, Geoghegan P, Povoa P, Nseir S, Rodriguez A, Martin-Loeches I, Systematic review on the first line treatment of amphotericin B in critically ill adults with candidemia or invasive candidiasis., Expert review of anti-infective therapy, 2018 Journal Article, 2018

, Community-Acquired Pneumonia: Now You See It, Now You Don't!, Chest, 2018 Journal Article, 2018 DOI

, Hemodynamic management of critically ill burn patients: an international survey, Critical care (London, England), 2018 Journal Article, 2018 DOI

, Murepavadin: a new antibiotic class in the pipeline, Expert review of anti-infective therapy, 2018 Journal Article, 2018 DOI

, Relationship between acute kidney injury and serum procalcitonin (PCT) concentration in critically ill patients with influenza infection, Medicina intensiva, 2018 Journal Article, 2018 DOI

Coelho L, Rabello L, Salluh J, Martin-Loeches I, Rodriguez A, Nseir S, Gomes JA, Povoa P, TAVeM study Group, C-reactive protein and procalcitonin profile in ventilator-associated lower respiratory infections., Journal of critical care, 2018 Journal Article, 2018

Bos LDJ, Azoulay E, Martin-Loeches I, Future of the ICU: finding treatable needles in the data haystack., Intensive care medicine, 2018 Journal Article, 2018

, New guidelines for hospital-acquired pneumonia/ventilator-associated pneumonia: USA vs. Europe, Current opinion in critical care, 2018 Journal Article, 2018 DOI

, Summary of the international clinical guidelines for the management of hospital-acquired and ventilator-acquired pneumonia, ERJ open research, 2018 Journal Article, 2018 DOI

, Twenty-year trend in mortality among hospitalized patients with pneumococcal community-acquired pneumonia, PloS one, 2018 Journal Article, 2018 DOI

, Fluid therapy in neurointensive care patients: ESICM consensus and clinical practice recommendations, Intensive care medicine, 2018 Journal Article, 2018 DOI

Kelly DN, Martin-Loeches I, Comparing current US and European guidelines for nosocomial pneumonia., Current opinion in pulmonary medicine, 2018 Journal Article, 2018

Rouzé A, Martin-Loeches I, Nseir S, Airway Devices in Ventilator-Associated Pneumonia Pathogenesis and Prevention., Clinics in chest medicine, 2018 Journal Article, 2018

, 23rd International Symposium on Infections in the Critically Ill Patient, Medical sciences (Basel, Switzerland), 2018 Journal Article, 2018 DOI

Nseir S, Martin-Loeches I, Hot topics in ventilator-associated pneumonia., Annals of translational medicine, 2018 Journal Article, 2018

, Corticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study, Intensive care medicine, 2018 Journal Article, 2018 DOI

Martin-Loeches I, Depuydt P, Niederman MS, Beat around the bush for VA-LRTI., Intensive care medicine, 2018 Journal Article, 2018

, Double Cycling During Mechanical Ventilation: Frequency, Mechanisms, and Physiologic Implications, Critical care medicine, 2018 Journal Article, 2018 DOI

, Clinical characteristics, evolution, and treatment-related risk factors for mortality among immunosuppressed patients with influenza A (H1N1) virus admitted to the intensive care unit, Journal of critical care, 2018 Journal Article, 2018 DOI

, Surviving sepsis campaign: research priorities for sepsis and septic shock, Intensive care medicine, 2018 Journal Article, 2018 DOI

, ARDS: challenges in patient care and frontiers in research, European respiratory review : an official journal of the European Respiratory Society, 2018 Journal Article, 2018 DOI

, Change is in the air: dying to breathe oxygen in acute respiratory distress syndrome?, Journal of thoracic disease, 2018 Journal Article, 2018 DOI

, Surviving Sepsis Campaign: Research Priorities for Sepsis and Septic Shock, Critical care medicine, 2018 Journal Article, 2018 DOI

Mathieu C, Pastene B, Cassir N, Martin-Loeches I, Leone M, Efficacy and safety of antimicrobial de-escalation as a clinical strategy., Expert review of anti-infective therapy, 2018 Journal Article, 2018

, Potentially modifiable respiratory variables contributing to outcome in ICU patients without ARDS: a secondary analysis of PRoVENT, Annals of intensive care, 2018 Journal Article, 2018 DOI

Almansa R, Nogales L, Martín-Fernández M, Batlle M, Villareal E, Rico L, Ortega A, López-Campos G, Andaluz-Ojeda D, Ramírez P, Socias L, Tamayo L, Martín-Loeches I, Transcriptomic depression of immunological synapse as a signature of ventilator-associated pneumonia., Annals of translational medicine, 2018 Journal Article, 2018

Manzano D, Izquierdo-Garcia JL, Martín-Loeches I, Lorente JA, Influenza A: New Therapeutic Targets for a Deadly Disease., Archivos de bronconeumologia, 2018 Journal Article, 2018

, Feasibility of Antimicrobial Stewardship (AMS) in Critical Care Settings: A Multidisciplinary Approach Strategy, Medical sciences (Basel, Switzerland), 2018 Journal Article, 2018 DOI

, Patients with influenza A (H1N1)pdm09 admitted to the ICU. Impact of the recommendations of the SEMICYUC, Medicina intensiva, 2018 Journal Article, 2018 DOI

, Management of invasive candidiasis and candidaemia in critically ill adults: expert opinion of the European Society of Anaesthesia Intensive Care Scientific Subcommittee, The Journal of hospital infection, 2018 Journal Article, 2018 DOI

, Extracorporeal membrane oxygenation in an HIV-positive man with severe acute respiratory distress syndrome secondary to pneumocystis and cytomegalovirus pneumonia, International journal of STD & AIDS, 2018 Journal Article, 2018 DOI

, Surgical antimicrobial prophylaxis in intensive care unit (ICU) patients: a preliminary, observational, retrospective study, Annals of translational medicine, 2018 Journal Article, 2018 DOI

, Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP), Intensive care medicine, 2018 Journal Article, 2018 DOI

Radovanovic D, Sotgiu G, Jankovic M, Mahesh PA, Marcos PJ, Abdalla MI, Di Pasquale MF, Gramegna A, Terraneo S, Blasi F, Santus P, Aliberti S, GLIMP Study Group, An international perspective on hospitalized patients with viral community-acquired pneumonia., European journal of internal medicine, 2018 Journal Article, 2018

, Impact of immunosuppression on incidence, aetiology and outcome of ventilator-associated lower respiratory tract infections, The European respiratory journal, 2018 Journal Article, 2018 DOI

Li Bassi G, Prats RG, Artigas A, Xiol EA, Marti JD, Ranzani OT, Rigol M, Fernandez L, Meli A, Battaglini D, Luque N, Ferrer M, Martin-Loeches I, Torres A, Appraisal of systemic inflammation and diagnostic markers in a porcine model of VAP: secondary analysis from a study on novel preventive strategies., Intensive care medicine experimental, 2018 Journal Article, 2018

Sakr Y, Jaschinski U, Wittebole X, Szakmany T, Lipman J, Ñamendys-Silva SA, Martin-Loeches I, Leone M, Lupu MN, Vincent JL, ICON Investigators, Sepsis in Intensive Care Unit Patients: Worldwide Data From the Intensive Care over Nations Audit., Open forum infectious diseases, 2018 Journal Article, 2018

, Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia: a multinational point prevalence study of hospitalised patients, The European respiratory journal, 2018 Journal Article, 2018 DOI

Martin C, Cortegiani A, Gregoretti C, Martin-Loeches I, Ichai C, Leone M, Marx G, Einav S, Choice of fluids in critically ill patients., BMC anesthesiology, 2018 Journal Article, 2018

Keane S, Vallecoccia MS, Nseir S, Martin-Loeches I, How Can We Distinguish Ventilator-Associated Tracheobronchitis from Pneumonia?, Clinics in chest medicine, 2018 Journal Article, 2018

, Current aspects in sepsis approach. Turning things around, Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2018 Journal Article, 2018

, Public awareness of sepsis is still poor: we need to do more, Intensive care medicine, 2018 Journal Article, 2018 DOI

, Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study), Intensive care medicine, 2018 Journal Article, 2018 DOI

, What's new in restoring the gut microbiota in ICU patients? Potential role of faecal microbiota transplantation, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2018 Journal Article, 2018 DOI

, Incidence of airway complications in patients using endotracheal tubes with continuous aspiration of subglottic secretions, Annals of intensive care, 2017 Journal Article, 2017 DOI

, On the verge of using an immune toolbox in the intensive care unit?, Intensive care medicine, 2017 Journal Article, 2017 DOI

, Epidemiology of sepsis in Catalonia: analysis of incidence and outcomes in a European setting, Annals of Intensive Care, 2017 Journal Article, 2017

, The dynamics of the pulmonary microbiome during mechanical ventilation in the intensive care unit and the association with occurrence of pneumonia, Thorax, 2017 Journal Article, 2017

, Identification and validation of distinct biological phenotypes in patients with acute respiratory distress syndrome by cluster analysis, Thorax, 2017 Journal Article, 2017 DOI

, Clinical characteristics and predictors of mortality in cirrhotic patients with candidemia and intra-abdominal candidiasis: a multicenter study, Intensive care medicine, 2017 Journal Article, 2017

, Research in community-acquired pneumonia: the next steps, Intensive Care Medicine, 2017 Journal Article, 2017

, What is new in severe sepsis in the critically ill patient?, Annals of translational medicine, 2017 Journal Article, 2017 DOI

, The pharmacological management of severe influenza infection--`existing and emerging therapies", Expert Review of Clinical Pharmacology, 2017 Journal Article, 2017

, Impact of Source Control in Patients With Severe Sepsis and Septic Shock, Critical Care Medicine, 2017 Journal Article, 2017

, Integrative research agenda for diagnosis in sepsis, Annals of translational medicine, 2017 Journal Article, 2017 DOI

, Increased incidence of co-infection in critically ill patients with influenza, Intensive Care Medicine, 2017 Journal Article, 2017

Ignacio Martin-Loeches, Robert Forster, Adriele Prina-Mello, Intensive care medicine in 2050: nanotechnology. Emerging technologies and approaches and their impact on critical care, Intensive Care Medicine, 2017 Journal Article, 2017

, The Effects of red Blood Cell Transfusion on Tissue Oxygenation and the Microcirculation in the Intensive Care Unit: A Systematic Review, Transfusion medicine reviews, 2017 Journal Article, 2017 DOI

, Should We Treat Ventilator-Associated Tracheobronchitis with Antibiotics?, Seminars in respiratory and critical care medicine, 2017 Journal Article, 2017 DOI

, Biomarker-guided antibiotic therapy-strengths and limitations, Annals of translational medicine, 2017 Journal Article, 2017 DOI

, International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: Guidelines for the management of hospital-acquired pneumonia (HAP)/ventilator-associated pneumonia (VAP) of the European Respiratory Society (ERS), European Society of Intensive Care Medicine (ESICM), European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and Asociación Latinoamericana del Tórax (ALAT), The European respiratory journal, 2017 Journal Article, 2017 DOI

, What were you able to do in your daily life? Performance status for the critically ill patient, 2017 Journal Article, 2017

, Balanced versus isotonic saline resuscitation-a systematic review and meta-analysis of randomized controlled trials in operation rooms and intensive care units, Annals of translational medicine, 2017 Journal Article, 2017 DOI

, In vitro evaluation of aerosol delivery of aztreonam lysine (AZLI): an adult mechanical ventilation model, Expert opinion on drug delivery, 2017 Journal Article, 2017 DOI

, Association between timing of intubation and outcome in critically ill patients: A secondary analysis of the ICON audit, Journal of critical care, 2017 Journal Article, 2017 DOI

, The role of open abdomen in non-trauma patient: WSES Consensus Paper, World journal of emergency surgery : WJES, 2017 Journal Article, 2017 DOI

Martin-Loeches Ignacio, Muriel-Bombin Arturo, Ferrer Ricard, Artigas Antonio, Sole-Violan Jordi, Lorente Leonardo, Andaluz-Ojeda David, Prina-Mello Adriele, Herran-Monge Ruben, Suberviola Borja, The protective association of endogenous immunoglobulins against sepsis mortality is restricted to patients with moderate organ failure , Annals of Intensive Care , 7 , (1 ), 2017, p44 - Journal Article, 2017 TARA - Full Text

, Pre-emptive and therapeutic value of blocking bacterial attachment to the endothelial alphaVbeta3 integrin with cilengitide in sepsis, Critical care (London, England), 2017 Journal Article, 2017 DOI

Ryan, T., Coakley, J.D., Martin-Loeches, I., Defects in innate and adaptive immunity in patients with sepsis and health care associated infection, Annals of Translational Medicine, 5, (22), 2017 Journal Article, 2017

, High endocan levels are associated with the need for mechanical ventilation among patients with severe sepsis, The European respiratory journal, 2017 Journal Article, 2017 DOI

, Acute hypoxemic respiratory failure in immunocompromised patients: the Efraim multinational prospective cohort study, Intensive care medicine, 2017 Journal Article, 2017 DOI

, Erratum to: Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA), World journal of emergency surgery : WJES, 2017 Journal Article, 2017 DOI

, Focus on infection and sepsis 2017, Intensive Care Medicine, 2017 Journal Article, 2017

, Predictors of treatment failure and clinical stability in patients with community acquired pneumonia, Annals of translational medicine, 2017 Journal Article, 2017 DOI

, Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference, World journal of emergency surgery : WJES, 2017 Journal Article, 2017 DOI

, Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis, Critical care (London, England), 2017 Journal Article, 2017 DOI

, Current challenges in the management of sepsis in ICUs in resource-poor settings and suggestions for the future, Intensive Care Medicine, 2017 Journal Article, 2017

, Intensive care unit patients with lower respiratory tract nosocomial infections: the ENIRRIs project, ERJ open research, 2017 Journal Article, 2017 DOI

, The research agenda in VAP/HAP: next steps, Intensive Care Medicine, 2017 Journal Article, 2017

, Decision-Making on Withholding or Withdrawing Life Support in the ICU: A Worldwide Perspective, Chest, 2017 Journal Article, 2017 DOI

, Antibiotic therapy in the critically ill-expert opinion of the Intensive Care Medicine Scientific Subcommittee of the European Society of Anaesthesiology, European Journal of Anaesthesiology (EJA), 2017 Journal Article, 2017

, Invasive Candida Infections in Liver Transplant Recipients: Clinical Features and Risk Factors for Mortality., Transplantation Direct, 2017 Journal Article, 2017

, Biomarkers kinetics in the assessment of ventilator-associated pneumonia response to antibiotics - results from the BioVAP study, Journal of critical care, 2017 Journal Article, 2017 DOI

, Systemic antibiotics for preventing ventilator-associated pneumonia in comatose patients: a systematic review and meta-analysis, Annals of intensive care, 2017 Journal Article, 2017 DOI

, Tools for outcome prediction in patients with community acquired pneumonia, Expert Review of Clinical Pharmacology, 2017 Journal Article, 2017

, Sepsis: frontiers in supportive care, organisation and research, Intensive care medicine, 2017 Journal Article, 2017

, Bacterial pneumonia as an influenza complication, Current opinion in infectious diseases, 2017 Journal Article, 2017

, BreathDx--molecular analysis of exhaled breath as a diagnostic test for ventilator--associated pneumonia: protocol for a European multicentre observational study, BMC Pulmonary Medicine, 2017 Journal Article, 2017

, Collaborative approach of individual participant data of prospective studies of de-escalation in non-immunosuppressed critically ill patients with sepsis, Expert Review of Clinical Pharmacology, 2017 Journal Article, 2017

, Respiratory research networks in Europe and beyond: aims, achievements and aspirations for the 21st century, Breathe (Sheffield, England), 2017 Journal Article, 2017 DOI

, Risk Factors for Noninvasive Ventilation Failure in Critically Ill Subjects With Confirmed Influenza Infection, Respiratory care, 2017 Journal Article, 2017 DOI

, Selection of right studies criteria to foster conclusions. Caveats for metanalysis conducted in sepsis, Heart & Lung: The Journal of Acute and Critical Care, 2017 Journal Article, 2017

, Microbial Etiology of Pneumonia: Epidemiology, Diagnosis and Resistance Patterns, International Journal of Molecular Sciences, 2016 Journal Article, 2016

, Epidemiological characteristics, practice of ventilation, and clinical outcome in patients at risk of acute respiratory distress syndrome in intensive care units from 16 countries (PRoVENT): an international, multicentre, prospective study, The Lancet Respiratory Medicine, 2016 Journal Article, 2016

, Neces-SARI-ly?, Intensive Care Med, 2016 Journal Article, 2016

, Piperacillin population pharmacokinetics in critically ill patients with multiple organ dysfunction syndrome receiving continuous venovenous haemodiafiltration: effect of type of dialysis membrane on dosing requirements, Journal of Antimicrobial Chemotherapy, 2016 Journal Article, 2016

, Focus on infection and sepsis in intensive care patients., Intensive care medicine, 2016 Journal Article, 2016

, Personalized medicine for ARDS: the 2035 research agenda, Intensive care medicine, 2016 Journal Article, 2016

O'Connor E, Martin-Loeches I, A blueprint for improving undergraduate education in intensive care medicine, Critical Care, 20, 2016, p212- Journal Article, 2016

, New definition of sepsis and septic shock: What does it give us?, Medicina intensiva, 2016 Journal Article, 2016

, Sharing Data from Cardiovascular Clinical Trials--A Proposal, The New England journal of medicine, 2016 Journal Article, 2016 DOI

, Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA), World Journal of Emergency Surgery, 2016 Journal Article, 2016

, Biomarker kinetics in the prediction of VAP diagnosis: results from the BioVAP study, Annals of intensive care, 2016 Journal Article, 2016

, Will all ARDS patients be receiving mechanical ventilation in 2035? Yes, 2016 Journal Article, 2016

, Global initiative for meticillin-resistant Staphylococcus aureus pneumonia (GLIMP): an international, observational cohort study, The Lancet. Infectious diseases, 2016 Journal Article, 2016 DOI

, What"s new in multidrug-resistant pathogens in the ICU?, Annals of intensive care, 2016 Journal Article, 2016

, Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis, Cytokine, 2016 Journal Article, 2016

, SEPsis REcognition and MAnagement (SEPREMA survey)., Intensive care medicine, 2016 Journal Article, 2016

, ESICM LIVES 2016: part two, Intensive care medicine experimental, 2016 Journal Article, 2016

, Intracerebral hemorrhage in ICU: is it worth treating?, INTENSIVE CARE MEDICINE EXPERIMENTAL, 2016 Journal Article, 2016

, Toward a personalized response approach in sepsis 4.0, Medicina Intensiva, 2016 Journal Article, 2016

, ESICM LIVES 2016: part three, Intensive care medicine experimental, 2016 Journal Article, 2016

, The significance of clinical scores and biological markers in disease severity, mortality prediction, and justifying hospital admissions in patients with community-acquired pneumonia, Community Acquired Infection, 2016 Journal Article, 2016

, Determinants of time to death in hospital in critically ill patients around the world, Intensive Care Medicine, 2016 Journal Article, 2016

, Duration of antibiotic therapy in the intensive care unit, Journal of Thoracic Disease, 2016 Journal Article, 2016

, What patient data should be collected in this randomized controlled trial in sepsis?, 2016 Journal Article, 2016

, Long term mortality following sepsis, Annals of Translational Medicine, 2016 Journal Article, 2016

, Is there a continuum between ventilator-associated tracheobronchitis and ventilator-associated pneumonia?, Intensive care medicine, 2016 Journal Article, 2016

, Collinearity and multivariable analysis: response to comments by Claret et al., Intensive Care Medicine, 2016 Journal Article, 2016

, Macrolide therapy of pneumonia: is it necessary, and how does it help?, Current opinion in infectious diseases, 2016 Journal Article, 2016

, Author's response to:" Harmful effects form one puff of shisha-pen vapor: methodological and interpretational problems in the risk assessment analysis", Tobacco induced diseases, 2016 Journal Article, 2016

, Cortical and subcortical grey matter morphometry for neuroprognostication after cardiac arrest, INTENSIVE CARE MEDICINE EXPERIMENTAL, 2016 Journal Article, 2016

, Delay in diagnosis of influenza A (H1N1)pdm09 virus infection in critically ill patients and impact on clinical outcome, Critical care (London, England), 2016 Journal Article, 2016 DOI

, Coagulopathy in fulminant liver failure with ultimately fatal clot formation, Intensive care medicine, 2016 Journal Article, 2016

, Finally time for rapid response systems to be well MET in Europe?, Intensive care medicine, 2016 Journal Article, 2016

, Evolution over a 15-year period of the clinical characteristics and outcomes of critically ill patients with severe community-acquired pneumonia, Medicina Intensiva (English Edition), 2016 Journal Article, 2016

, Impact of Candida spp. isolation in the respiratory tract in patients with intensive care unit-acquired pneumonia, Clinical Microbiology and Infection, 2016 Journal Article, 2016

, Procalcitonin (PCT) levels for ruling-out bacterial coinfection in ICU patients with influenza: a CHAID decision-tree analysis, Journal of Infection, 2016 Journal Article, 2016

, Contrast-enhanced signs of cardiac arrest during CT., Medicina intensiva/Sociedad Espanola de Medicina Intensiva y Unidades Coronarias, 2015 Journal Article, 2015

, Lung health care"what does the future have in store?, The Lancet Respiratory Medicine, 2015 Journal Article, 2015

, Management of severe sepsis: advances, challenges, and current status, Drug design, development and therapy, 2015 Journal Article, 2015

, Being overweight is associated with greater survival in ICU patients: results from the intensive care over nations audit, Critical care medicine, 2015 Journal Article, 2015

, Update on the combination effect of macrolide antibiotics in community-acquired pneumonia, Respiratory investigation, 2015 Journal Article, 2015

, Tumor necrosis factor receptor 1 (TNFRI) for ventilator-associated pneumonia diagnosis by cytokine multiplex analysis, Intensive care medicine experimental, 2015 Journal Article, 2015

, Resistance patterns and outcomes in intensive care unit (ICU)-acquired pneumonia. Validation of European Centre for Disease Prevention and Control (ECDC) and the Centers for Disease Control and Prevention (CDC) classification of multidrug resistant organisms, Journal of Infection, 2015 Journal Article, 2015

, Meropenem population pharmacokinetics in critically ill patients with septic shock and continuous renal replacement therapy: influence of residual diuresis on dose requirements, Antimicrobial agents and chemotherapy, 2015 Journal Article, 2015

, Regional oxygen saturation index (rSO 2) in brachioradialis and deltoid muscle. Correlation and prognosis in patients with respiratory sepsis, Medicina Intensiva (English Edition), 2015 Journal Article, 2015

, In the name of ventilator-associated pneumonia prevention: lung microbiota blown away by colistin!, 2015 Journal Article, 2015

, Pneumococcal pneumonia coinfection in critically ill patients with influenza a (h1n1) primary viral pneumonia, Intensive care medicine experimental, 2015 Journal Article, 2015

, Incidence and prognosis of ventilator-associated tracheobronchitis (TAVeM): a multicentre, prospective, observational study, The Lancet Respiratory Medicine, 2015 Journal Article, 2015

, COPD patients with ventilator-associated pneumonia: implications for management, European Journal of Clinical Microbiology & Infectious Diseases, 2015 Journal Article, 2015

, D-Dimer elevation and adverse outcomes, Journal of thrombosis and thrombolysis, 2015 Journal Article, 2015

, Chromogranin A levels and mortality in patients with severe sepsis, Biomarkers, 2015 Journal Article, 2015

, International study on microcirculatory shock occurrence in acutely ill patients, Critical care medicine, 2015 Journal Article, 2015 DOI

, Grado de adherencia al tratamiento antiv""rico recomendado durante la pandemia y periodo pospandémico de gripe A (H1N1) pdm09 en 148 unidades de cuidados intensivos espanolas, Medicina Intensiva, 2015 Journal Article, 2015

, Impact of non-invasive mechanical ventilation (niv) in critical patients with influenza (H1N1) PDM09, Intensive care medicine experimental, 2015 Journal Article, 2015

, Degree of adherence to recommended antiviral treatment during the pandemic and post-pandemic periods of influenza A (H1N1) pdm09 in 148 intensive care units in Spain, Medicina Intensiva (English Edition), 2015 Journal Article, 2015

, Efficiency of a mechanical device in controlling tracheal cuff pressure in intubated critically ill patients: a randomized controlled study, Annals of intensive care, 2015 Journal Article, 2015

, Factors associated with misdiagnosis: the usefulness of necropsy, Intensive care medicine experimental, 2015 Journal Article, 2015

, Biomarker Kinetics in VAP, Clinical Pulmonary Medicine, 2015 Journal Article, 2015

, Empiric antibiotic treatment reduces mortality in severe sepsis and septic shock from the first hour: results from a guideline-based performance improvement program, Critical care medicine, 2014 Journal Article, 2014

, Impact of appropriate antimicrobial treatment on transition from ventilator-associated tracheobronchitis to ventilator-associated pneumonia, Critical Care, 2014 Journal Article, 2014

, Advanced Machine Learning for classification of EEG traits as Parkinson"s biomarker, Frontiers in Neuroinformatics, 2014 Journal Article, 2014

, DEGREE OF ADHERENCE TO RECOMMENDED ANTIVIRAL TREATMENT DURING THE PANDEMIC AND POST-PANDEMIC PERIODS OF INFLUENZA A (H1N1) PDM09 IN 148 UCIS IN SPAIN, INTENSIVE CARE MEDICINE, 2014 Journal Article, 2014

, Training in Intensive Care Medicine. A challenge within reach, Medicina Intensiva (English Edition), 2014 Journal Article, 2014

, IgA level in plasma as a differential factor for influenza infection in severe viral pneumonia., Journal of clinical virology: the official publication of the Pan American Society for Clinical Virology, 2014 Journal Article, 2014

, Epidemiology, antibiotic therapy and clinical outcomes of healthcare-associated pneumonia in critically ill patients: a Spanish cohort study, Intensive care medicine, 2014 Journal Article, 2014

, Risks for multidrug-resistant pathogens in the ICU, Current opinion in critical care, 2014 Journal Article, 2014

, TRENDS IN INCIDENCE AND HOSPITAL OUTCOMES AMONG PATIENTS WITH SEVERE SEPSIS IN CATALONIA DURING THE 2008-2012 PERIOD, INTENSIVE CARE MEDICINE, 2014 Journal Article, 2014

, Treating HSV and CMV reactivations in critically ill patients who are not immunocompromised: pro, 2014 Journal Article, 2014

, Innovations that could improve early recognition of ventilator-associated pneumonia, Intensive care medicine, 2014 Journal Article, 2014

, Ventilator-associated tracheobronchitis: where are we now?, Revista Brasileira de terapia intensiva, 2014 Journal Article, 2014

, The volatile metabolic fingerprint of ventilator-associated pneumonia, Intensive care medicine, 2014 Journal Article, 2014

, Beta-lactam dosing in critically ill patients with septic shock and continuous renal replacement therapy, Critical Care, 2014 Journal Article, 2014

, Impact of de-escalation on ICU patients" prognosis, 2014 Journal Article, 2014

, Are preoperative oral care bundles needed to prevent postoperative pneumonia?, Intensive care medicine, 2014 Journal Article, 2014

, Oxidative stress in immunocompetent patients with severe community-acquired pneumonia. A pilot study, Medicina Intensiva (English Edition), 2014 Journal Article, 2014

, Community acquired pneumonia: Genetic variants influencing systemic inflammation, Medicina Intensiva (English Edition), 2014 Journal Article, 2014

, Prevalence, risk factors, and mortality for ventilator-associated pneumonia in middle-aged, old, and very old critically ill patients, Critical care medicine, 2014 Journal Article, 2014

, Inflammation and infection in critical care medicine, Mediators of inflammation, 2014 Journal Article, 2014

, Antibiotika senken Mortalität bei Sepsis, Journal Club AINS, 2014 Journal Article, 2014

, Formación en Medicina Intensiva. Un reto a nuestro alcance, Medicina Intensiva, 2014 Journal Article, 2014

, FEASIBILITY OF A PNEUMATIC DEVICE IN CONTROLLING TRACHEAL CUFF PRESSURE IN INTUBATED CRITICALLY ILL PATIENTS, INTENSIVE CARE MEDICINE, 2014 Journal Article, 2014

, Neumon""a adquirida en la comunidad: variantes génicas implicadas en la inflamación sistémicamación sistémica, Medicina Intensiva, 2014 Journal Article, 2014

, FLUID BALANCE AND BIOMARKERS OF ACUTE KIDNEY INJURY, INTENSIVE CARE MEDICINE, 2014 Journal Article, 2014

, Assessment of the worldwide burden of critical illness: the Intensive Care Over Nations (ICON) audit, The lancet Respiratory medicine, 2014 Journal Article, 2014

, SEVERE COMMUNITY-ACQUIRED PNEUMONIA (SCAP): 15 YEARS EXPERIENCE IN A SINGLE CENTER, INTENSIVE CARE MEDICINE, 2014 Journal Article, 2014

, Assessment of the taxi sector efficiency and profitability based on continuous monitoring and methodology to review fares, Transportation Research Board, Washington, DC, 2014 Journal Article, 2014

, Incidence and diagnosis of ventilator-associated tracheobronchitis in the intensive care unit: an international online survey, Critical Care, 2014 Journal Article, 2014

, Predicting treatment failure in patients with community acquired pneumonia: a case-control study, Respiratory research, 2014 Journal Article, 2014

, Optimal care and design of the tracheal cuff in the critically ill patient, Annals of intensive care, 2014 Journal Article, 2014

, [Why macrolides?], The Japanese journal of antibiotics, 2014 Journal Article, 2014

, TISSUE OXYGEN SATURATION LNDEX (RSO2) IN BRACHIORADIALIS (BR)) AND DELTOID LID MUSCLE. CORRELATION AND PROGNOSIS IN PATIENTS WITH RESPIRATORY SEPSIS, INTENSIVE CARE MEDICINE, 2013 Journal Article, 2013

, AZITHROMYCLN DOES NOT AFFECT MORTALITY AMONG PATIENT WITH SEVERE SEPSIS: A PILOT RANDOMIZED CONTROLLED TRIAL, INTENSIVE CARE MEDICINE, 2013 Journal Article, 2013

, Bacteriemia adquirida en la comunidad en pacientes cr""ticamente enfermos, Crit Care Med, 2013 Journal Article, 2013

, Genetic Polymorphisms of Systemic Inflammation in Community-acquired Pneumonia, Clinical Pulmonary Medicine, 2013 Journal Article, 2013

, POINT/COUNTERPOINT EDITORIALS, CHEST, 2013 Journal Article, 2013

, Immunological monitoring to prevent and treat sepsis, Critical Care, 2013 Journal Article, 2013

, [Nosocomial pneumonia], Enfermedades infecciosas y microbiologia clinica, 2013 Journal Article, 2013 DOI

, Macrolide-based regimens in absence of bacterial co-infection in critically ill H1N1 patients with primary viral pneumonia, Intensive care medicine, 2013 Journal Article, 2013

, Effectiveness of an inspiratory pressure-limited approach to mechanical ventilation in septic patients, European Respiratory Journal, 2013 Journal Article, 2013

, Potentially resistant microorganisms in intubated patients with hospital-acquired pneumonia: the interaction of ecology, shock and risk factors, Intensive care medicine, 2013 Journal Article, 2013

, Correlates of motivation to practice physical activity among students from Portuguese military college, British journal of sports medicine, 2013 Journal Article, 2013

, Efficacy of single-dose antibiotic against early-onset pneumonia in comatose patients who are ventilated, CHEST Journal, 2013 Journal Article, 2013

, Rationale and study design of provent"an international multicenter observational study on practice of ventilation in critically ill patients without ARDS, J Clin Trials, 2013 Journal Article, 2013

, From ventilator-associated tracheobronchitis to ventilator-associated pneumonia, Reanimation, 2013 Journal Article, 2013

, Antibiotic Prophylaxis for Ventilator-Associated Pneumonia More Is Less or Less Is More? Response, CHEST, 2013 Journal Article, 2013

, Evolution over a 15-year period of clinical characteristics and outcomes of critically ill patients with community-acquired bacteremia, Critical care medicine, 2013 Journal Article, 2013

, GTEI/SEMICYUC Working Group on Bacteremia. Evolution over a 15-year period of clinical characteristics and outcomes of critically ill patients with community-acquired bacteremia, Crit Care Med, 2013 Journal Article, 2013

, A week seems to be weak: tailoring duration of antibiotic treatment in Gram-negative ventilator-associated pneumonia, Critical Care, 2013 Journal Article, 2013

, Nosocomial pneumonia, Enfermedades infecciosas y microbiologia clinica, 2013 Journal Article, 2013

, 'VOLATILE METABOLITE FINGERPRINTS'OF TRACHEAL ASPIRATES DISCRIMINATES PATIENTS WITH VAP FROM CONTROLS, INTENSIVE CARE MEDICINE, 2013 Journal Article, 2013

, Acute respiratory distress syndrome: prevention and early recognition, Annals of intensive care, 2013 Journal Article, 2013

, Neumon""a nosocomial, Enfermedades Infecciosas y Microbiolog""a Cl""nica, 2013 Journal Article, 2013

, IgM levels in plasma predict outcome in severe pandemic influenza, Journal of Clinical Virology, 2013 Journal Article, 2013

, Antibiotic prescription patterns in the empiric therapy of severe sepsis: combination of antimicrobials with different mechanisms of action reduces mortality, Critical Care, 2012 Journal Article, 2012

, Corticosteroid therapy in patients with primary viral pneumonia due to pandemic (H1N1) 2009 influenza, Journal of Infection, 2012 Journal Article, 2012

, Situación actual de la realización de fibrobroncoscopias en los Servicios de Medicina Intensiva, Medicina intensiva, 2012 Journal Article, 2012

, Los pacientes intubados que presentan traqueobronquitis o neumon""a tienen patrones distintivos de expresión genética del sistema del complemento en el per""odo previo a la infección: un estudio piloto, Medicina Intensiva, 2012 Journal Article, 2012

, [Extracorporeal lung support in patients with severe respiratory failure secondary to the 2010-2011 winter seasonal outbreak of influenza A (H1N1) in Spain], Medicina intensiva, 2012 Journal Article, 2012 DOI

, Uso de oxigenador de membrana extracorpóreo en pacientes con insuficiencia respiratoria aguda grave refractaria en la epidemia de gripe estacional 2010-2011 por influenza A (H1N1) en España, Medicina intensiva, 2012 Journal Article, 2012

, Intubated patients developing tracheobronchitis or pneumonia have distinctive complement system gene expression signatures in the pre-infection period: a pilot study, Medicina Intensiva (English Edition), 2012 Journal Article, 2012

, Recommendations of the Infectious Diseases Work Group (GTEI) of the Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC) and the Infections in Critically Ill Patients Study Group (GEIPC) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) for the diagnosis and treatment of influenza A/H1N1 in seriously ill adults admitted to the intensive care unit, Medicina Intensiva (English Edition), 2012 Journal Article, 2012

, Educação F""sica: uma disciplina, diferentes perspetivas. Implicações práticas, Boletim SPEF, 2012 Journal Article, 2012

, Variants at the promoter of the interleukin-6 gene are associated with severity and outcome of pneumococcal community-acquired pneumonia, Intensive care medicine, 2012 Journal Article, 2012

, Tracheostomy And Risk Of Ventilator-Associated Pneumonia At Latin American Intensive Care Units (icus), D62. NOSOCOMIAL INFECTIONS: BACTERIOLOGY, DRUG RESISTANCE, AND OUTCOMES, 2012 Journal Article, 2012

, Recomendaciones del Grupo de Trabajo Enfermedades Infecciosas (GTEI) de la Sociedad Española de Medicina Intensiva, Cr""tica y Unidades Coronarias (SEMICYUC) y el Grupo de Estudio de Infecciones en el Paciente Cr""tico (GEIPC) de la Sociedad Española de Enfermedades Infecciosas y Microbiolog""a cl""nica (SEIMC) para el diagnóstico y tratamiento de la gripe A/H1N1 en pacientes adultos graves hospitalizados en las Unidades de Cuidados Intensivos, Medicina intensiva, 2012 Journal Article, 2012

, Critical COPD respiratory illness is linked to increased transcriptomic activity of neutrophil proteases genes, BMC research notes, 2012 Journal Article, 2012

, [Recommendations of the Infectious Diseases Work Group (GTEI) of the Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC) and the Infections in Critically Ill Patients Study Group (GEIPC) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) for the diagnosis and treatment of influenza A/H1N1 in seriously ill adults admitted to the Intensive Care Unit], Medicina intensiva, 2012 Journal Article, 2012 DOI

, Impact Of Time To Broad-Spectrum Antibiotic On Mortality Of Severe Sepsis And Septic Shock. Results From The Surviving Sepsis Campaign, C24. THIS CAN BE DONE BETTER: QUALITY, SAFETY AND PROCESS IMPROVEMENT IN CRITICAL CARE, 2012 Journal Article, 2012

, Interleukin-6 is a potential biomarker for severe pandemic H1N1 influenza A infection, PloS one, 2012 Journal Article, 2012

, PMC3603106., Intensive Care Med, 2012 Journal Article, 2012

, Current status of fiberoptic bronchoscopy in intensive care medicine, Medicina Intensiva (English Edition), 2012 Journal Article, 2012

, Extracorporeal lung support in patients with severe respiratory failure secondary to the 2010--2011 winter seasonal outbreak of influenza A (H1N1) in Spain, Medicina Intensiva (English Edition), 2012 Journal Article, 2012

, The Complex Interaction between Sepsis and Lung Injury, Annual Update in Intensive Care and Emergency Medicine 2012, 2012 Journal Article, 2012

, Severity assessment tools in ICU patients with 2009 Influenza A (H1N1) pneumonia, Clinical microbiology and infection, 2012 Journal Article, 2012

, [Clinical pathways in acute pancreatitis: recommendations for early multidisciplinary management. Scientific Committee of the SEMICYUC. Working Group on Infectious Diseases (GTEI-SEMICYUC)], Medicina intensiva, 2012 Journal Article, 2012 DOI

, EFFECTIVENESS OF INSPIRATORY PRESSURE-LIMITED APPROACH TO MECHANICAL VENTILATION IN SEPTIC PATIENTS, INTENSIVE CARE MEDICINE, 2012 Journal Article, 2012

, Overtreating or underdiagnosing invasive pulmonary aspergillosis (IPA) in critically ill H1N1 patients: who is right?, 2012 Journal Article, 2012

, Viral infection is associated with an increased proinflammatory response in chronic obstructive pulmonary disease, Viral immunology, 2012 Journal Article, 2012

, [Current status of fibreoptic bronchoscopy in intensive care medicine], Medicina intensiva, 2012 Journal Article, 2012 DOI

, Severity and outcomes of hospitalised community-acquired pneumonia in COPD patients, European Respiratory Journal, 2012 Journal Article, 2012

, ESICM H1N1 Registry Contributors: Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1) v influenza A infection, Intensive Care Med, 2011 Journal Article, 2011

, Severe 2009 A/H1N1v influenza in pregnant women in Spain, Critical care medicine, 2011 Journal Article, 2011

, Current Key Points in Management for Severe Community-Acquired Pneumonia, Current Respiratory Medicine Reviews, 2011 Journal Article, 2011

, Pandemic and post-pandemic influenza A (H1N1) infection in critically ill patients, Critical care, 2011 Journal Article, 2011

, Mortality and regional oxygen saturation index in septic shock patients: a pilot study, Journal of Trauma and Acute Care Surgery, 2011 Journal Article, 2011

White M, Martin-Loeches I, Lawless MW, O'Dwyer MJ, Doherty DG, Young V, Kelleher D, McManus R, Ryan T, Hospital-acquired pneumonia after lung resection surgery is associated with characteristic cytokine gene expression., Chest, 139, (3), 2011, p626-32 Journal Article, 2011 DOI

, First influenza season after the 2009 pandemic influenza: report of the first 300 ICU admissions in Spain, Medicina Intensiva (English Edition), 2011 Journal Article, 2011

, Impact of obesity in patients infected with 2009 influenza A (H1N1), CHEST Journal, 2011 Journal Article, 2011

, Imbalanced pro-and anti-Th17 responses (IL-17/granulocyte colony-stimulating factor) predict fatal outcome in 2009 pandemic influenza, Critical Care, 2011 Journal Article, 2011

, Bacteremia is an independent risk factor for mortality in nosocomial pneumonia: a prospective and observational multicenter study, Critical care, 2011 Journal Article, 2011

, Direct association between pharyngeal viral secretion and host cytokine response in severe pandemic influenza, BMC infectious diseases, 2011 Journal Article, 2011

, Community-acquired respiratory coinfection in critically ill patients with pandemic 2009 influenza A (H1N1) virus, CHEST Journal, 2011 Journal Article, 2011

Vincent Jean-Louis, Martin-Loeches I., Ulldemolins M., Diaz E., A New Approach to Ventilator-associated Pneumonia Based on the PIRO System , Annual Update in Intensive Care and Emergency Medicine 2011 , 1 , 2011, p481 - 492 Journal Article, 2011 URL

, Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1) v influenza A infection, Intensive care medicine, 2011 Journal Article, 2011

, Patient to nurse ratio and risk of ventilator-associated pneumonia in critically ill patients, American Journal of Critical Care, 2011 Journal Article, 2011

, Primera epidemia de gripe estacional después de la pandemia por gripe A en 2009: descripción de los primeros 300 ingresos en UCI españolas, Medicina Intensiva, 2011 Journal Article, 2011

, PANDEMIC 2009 INFLUENZA A (H1N1) AND AN/H1N1 2010-11 SEASONAL OUTBREAK: MORTALITY AND RISK FACTORS IN CRITICALLY ILL PATIENTS, INTENSIVE CARE MEDICINE, 2011 Journal Article, 2011

, Severe pandemic (H1N1) v influenza A infection: report on the first deaths in Spain, Respirology, 2011 Journal Article, 2011

, Impact of early oseltamivir treatment on outcome in critically ill patients with 2009 pandemic influenza A, Journal of antimicrobial chemotherapy, 2011 Journal Article, 2011

, Determinants of prescription and choice of empirical therapy for hospital-acquired and ventilator-associated pneumonia, European Respiratory Journal, 2011 Journal Article, 2011

, A new approach to ventilator-associated pneumonia based on the PIRO system, Annual Update in Intensive Care and Emergency Medicine 2011, 2011 Journal Article, 2011

, Ventilator Associated Tracheobronchitis, Bronchitis, 2011 Journal Article, 2011

, Acute kidney injury in critical ill patients affected by influenza A (H1N1) virus infection, Critical Care, 2011 Journal Article, 2011

, Severe Pandemic (H1N1) Influenza A Infection, Clinical Pulmonary Medicine, 2011 Journal Article, 2011

, BACTERIAL PNEUMONIA COMPLICATING INFLUENZA A (H1N1) V VIRAL PNEUMONIA: RESULTS OF THE ESICM INFLUENZA A (H1N1) V REGISTRY, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, Community-Acquired Respiratory Coinfection in Critically Ill Patients Infected With Pandemic 2009 Influenza A (H1N1) Virus Infection, 2010 Journal Article, 2010

, PULMONARY VERSUS NON PULMONARY PRESENTATION IN SEVERE PANDEMIC INFLUENZA A (H1N1) V, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, What is new in ventilator-associated tracheobronchitis?, Clinical Pulmonary Medicine, 2010 Journal Article, 2010

, COMPARATIVE STUDY OF PATIENTS ADMITTED IN INTENSIVE CARE WITH INFLUENZA A (H1N1) V. COMPARATIVE STUDY OF EUROPE VERSUS LATIN AMERICA. RESULTS OF THE ESICM INFLUENZA A (H1N1) V REGISTRY, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, Determinants of choice and prescription patterns in empiric antibiotic therapy for HAP/VAP, European Respiratory Journal, 2010 Journal Article, 2010

, Combination antibiotic therapy with macrolides improves survival in intubated patients with community-acquired pneumonia, Intensive care medicine, 2010 Journal Article, 2010

, PIRO-CAP IN PANDEMIC INFLUENZA A (H1N1) V: RESULTS OF THE ESICM INFLUENZA A (H1N1) V REGISTRY, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, CLINICAL CHARACTERISTICS IN A COHORT OF CRITICALLY ILL PATIENTS INFECTED WITH PANDEMIC INFLUENZA A (H1N1) V RECEIVING EXTRACORPOREAL MEMBRANE OXIGENATION (ECMO) THE ESICM H1N1 REGISTRY, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, Clinical characteristics in a cohort of critically ill patients infected with pandemic influenza A (H1N1) V: The ESiCM H1N1 registry, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, HOSPITAL ACQUIRED PNEUMONIA AFTER LUNG RESECTION SURGERY DISPLAYS CHARACTERISTIC CYTOKINE PROFILES, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, Traqueobronquite associada ao ventilador: onde nos encontramos?., Revista Brasileira de Terapia Intensiva, 2010 Journal Article, 2010

, Reply to Westley and Chan and to Shih et al., Intensive Care Medicine, 2010 Journal Article, 2010

, Curb-65 in pandemic influenza a (H1N1) v: Results of the esicm influenza a (H1N1) v registry, Intensive Care Medicine, 2010 Journal Article, 2010

, Genetic variability in the severity and outcome of community-acquired pneumonia, Respiratory medicine, 2010 Journal Article, 2010

, Cytokine profiles of suction pulmonary secretions from children infected with pandemic influenza A (H1N1) 2009 Response, CRITICAL CARE, 2010 Journal Article, 2010

, Ventilator-associated pneumonia in trauma patients is associated with lower mortality: results from EU-VAP study, The Journal of trauma, 2010 Journal Article, 2010 DOI

, MORTALITY ASSOCIATED TO SEVERE PANDEMIC H1N1 INFLUENZA A INFECTION, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, BACTERIAL CO-INFECTION IN CRITICALLY ILL PATIENTS INFECTED WITH PANDEMIC (H1N1) V INFLUENZA A INFECTION, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, Proinflamatory and Autoimmune-like Cytokines Profiles in Severe Pandemic Influenza H1N1 Disease, Clinical Immunology, 2010 Journal Article, 2010

, Use of corticosteroid therapy in patients affected by severe pandemic (H1N1) V influenza A infection, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, Host adaptive immunity deficiency in severe pandemic influenza, Critical Care, 2010 Journal Article, 2010

, SEVERE COMMUNITY-ACQUIRED PNEUMONIA IN EUROPE: RESULTS FROM EU-VAP/CAP STUDY, INTENSIVE CARE MEDICINE, 2009 Journal Article, 2009

, Spectrum of practice in the diagnosis of nosocomial pneumonia in patients requiring mechanical ventilation in European intensive care units, Critical care medicine, 2009 Journal Article, 2009

, Mortality in ICU patients with bacterial community-acquired pneumonia: when antibiotics are not enough, Intensive care medicine, 2009 Journal Article, 2009

, Protocolo de manejo de la Insuficiencia Respiratoria Aguda Grave en pacientes con neumon""a viral primaria por el nuevo virus de la Gripe A (H1N1) en UCI, Science, 2009 Journal Article, 2009

, Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza, Critical Care, 2009 Journal Article, 2009

, Management of Sepsis: The PIRO Approach, 2009 Journal Article, 2009

, Community-Acquired Pneumonia Intensive Care Units (CAPUCI) Study Inves tigators. Mortality in ICU patients with bacterial community-acquired pneumonia: when antibiotics are not enough, Intensive Care Med, 2009 Journal Article, 2009

, Community-Acquired Pneumonia Management Based on the PIRO System. A New Therapeutic Paradigm, Management of Sepsis: The PIRO Approach, 2009 Journal Article, 2009

, Effect of the IL-6 promoter polymorphism-174 G/C on risk and outcome of pneumonia, Critical Care, 2008 Journal Article, 2008

, Combination antibiotic therapy improves survival in patients with community-acquired pneumonia and shock, Critical care medicine, 2007 Journal Article, 2007

Eleanor Molloy, Michelle Walsh, Response, J Perinatol, 25, (5), 2005, p360--360 Journal Article, 2005

Gallagher L., Fitzgerald M. , Focus on Autism, Irish Journal of Clinical Medicine,, 32, (5), 2002, p14 - 24 Journal Article, 2002 URL

, Lens transmission and autofluorescence in renal disease, Ophthalmic research, 1988 Journal Article, 1988

B.R. Ballinger, J. Feely, Antidepressants, British Medical Journal , 286, 1983, p1885 - 1887 Journal Article, 1983

, Effects of biomechanics and of dressings with calcium hydroxide, 1% paramonochlorophenol or a combination of both on reduction of microbial flora of infected root canals, Ars curandi em odontologia, 1979 Journal Article, 1979

, Efeitos da biomec"anica e de curativos de demora com hidróxido de cálcio, paramonoclorofenol a 1% ou associação de ambos na redução da flora microbiana dos canais radiculares infectados, ARS Cvrandy em Odontologia, 1979 Journal Article, 1979

, EvOLuCIóN DuRANTE uN PERÍODO DE 15 AÑOS DE LAS CARACTERÍSTICAS CLÍNICAS y RESuLTADOS DE LOS PACIENTES CRÍTICAMENTE ENfERMOS CON NEuMONÍA COMuNITARIA gRAvE Journal Article,

, Médecine Intensive Réanimation Journal Article,

, Annals of Intensive Care Journal Article,

Non-Peer-Reviewed Publications

martin-loeches , ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients, ICM, 2019, p10.1007/s00134-019-05599-w Journal Article, 2019

Research Expertise

Projects

  • Title
    • SFI
  • Summary
    • COVID critical care
  • Funding Agency
    • SFI
  • Title
    • Microbiome in pneumonia
  • Funding Agency
    • JPIAMR

Keywords

ARDS; COMMUNITY ACQUIRED PNEUMONIA; NOSOCOMIAL PNEUMONIA; SEPSIS; VENTILATOR-ASSOCIATED PNEUMONIA

Recognition

Representations

Strategic Advisor under the Group of Experts (SAGE) on Influenza for World Health Organization (WHO). 2008

Chair for COBATRICE at the ESICM 2018

Secretary of Group 02.01 - Acute Critical Care by ERS members of your group. 2019

Executive Member of the Education and Training Committee for the European Respiratory Society. Respiratory Critical Care HERMES program. 2016

External Examiner European Diploma Intensive Care Medicine 2018

Awards and Honours

Summa Cum laude 2008

Clinical Excellence award Spanish Society of Intensive Care Medicine 2006

Senior investigator for the European society of Intensive Care Medicine 2018