Research
Single molecule manipulation and biosensing using optical tweezer and MEMS diagnostic technology - Bioanalytics @ Molecular Level
Sensing Tools for Nano-Systems Investigations
Optical Tweezers
Force resolution 0.1 pN - 200pN
Position Resolution 0.1 nm
Projects: Single Molecule mechanics and spectroscopy:
Current highlights: VirE2 dynamics, dsDNA Mechanics (pdf),
Mitochondria import, Ribosomal mechanics
Scanning Force Microscopy
Force resolution 10 pN - 4nN
Position Resolution 0.1 nm
Projects: Single Molecule mechanics and spectroscopy:
Recent project: Nanomechanical Protein Folding (pdf)
Sensing Tools for Macro-Systems Investigations
Nanomechanical Cantilever Arrays
pN Interaction Forces transduced into nanomechanical motion
Position Resolution 0.1 nm
Projects: Gene fishing, Proteomics sensors, Microorganism
sensors, Membrane protein sensors, Ion sensors, Gas sensors.
Current highlight: Tiny Springboards detect Viruses in Fluids