Professor Lidia Tajber

• Wojnarowska Z, Paluch KJ, Shoifet E, Schick C, Tajber L, Knapik J, Wlodarczyk P, Grzybowska K, Hensel-Bielowka S, Verevkin SP, Paluch M, Molecular origin of enhanced proton conductivity in anhydrous ionic systems., Journal of the American Chemical Society, 137, (3), 2015, p1157 - 1164Journal Article, 2015, DOI
• Grossjohann C, Serrano DR, Paluch KJ, O'Connell P, Vella-Zarb L, Manesiotis P, Mccabe T, Tajber L, Corrigan OI, Healy AM, Polymorphism in sulfadimidine/4-aminosalicylic acid cocrystals: solid-state characterization and physicochemical properties., Journal of Pharmaceutical Sciences, 104, (4), 2015, p1385 - 1398Journal Article, 2015, DOI
• Amaro MI, Tewes F, Gobbo O, Tajber L, Corrigan OI, Ehrhardt C, Healy AM, Formulation, stability and pharmacokinetics of sugar-based salmon calcitonin-loaded nanoporous/nanoparticulate microparticles (NPMPs) for inhalation., International Journal of Pharmaceutics, 483, (1-2), 2015, p6 - 18Journal Article, 2015, DOI
• Dul M, Paluch KJ, Kelly H, Healy AM, Sasse A, Tajber L, Self-assembled carrageenan/protamine polyelectrolyte nanoplexes-Investigation of critical parameters governing their formation and characteristics., Carbohydrate Polymers, 123, 2015, p339 - 349Journal Article, 2015, DOI , TARA - Full Text
• Umerska A, Paluch KJ, Santos-Martinez MJ, Medina C, Corrigan OI, Tajber L, Chondroitin-based nanoplexes as peptide delivery systems--Investigations into the self-assembly process, solid-state and extended release characteristics., European Journal of Pharmaceutics and Biopharmaceutics, 93, 2015, p242 - 253Journal Article, 2015, DOI , TARA - Full Text
• Wlodarski K, Sawicki W, Haber K, Knapik J, Wojnarowska Z, Paluch M, Lepek P, Hawelek L, Tajber L, Physicochemical properties of tadalafil solid dispersions - Impact of polymer on the apparent solubility and dissolution rate of tadalafil., European Journal of Pharmaceutics and Biopharmaceutics, 94, 2015, p106 - 115Journal Article, 2015, DOI
• Knopp MM, Tajber L, Tian Y, Olesen NE, Jones DS, Kozyra A, Löbmann K, Paluch K, Brennan CM, Holm R, Healy AM, Andrews GP, Rades T, Comparative study of different methods for the prediction of drug-polymer solubility, Molecular Pharmaceutics, 12, (9), 2015, p3408 - 3419Journal Article, 2015, DOI , TARA - Full Text
• Wlodarski K, Sawicki W, Kozyra A, Tajber L, Physical stability of solid dispersions with respect to thermodynamic solubility of tadalafil in PVP-VA., European Journal of Pharmaceutics and Biopharmaceutics, 96, 2015, p237 - 246Journal Article, 2015, DOI , TARA - Full Text
• Mugheirbi NA, Tajber L, Mesophase and size manipulation of itraconazole liquid crystalline nanoparticles produced via quasi nanoemulsion precipitation., European Journal of Pharmaceutics and Biopharmaceutics, 96, 2015, p226 - 236Journal Article, 2015, DOI , TARA - Full Text
• Mugheirbi NA, Tajber L, Crystal habits of itraconazole microcrystals: unusual isomorphic intergrowths induced via tuning recrystallization conditions, Molecular Pharmaceutics, 12, (9), 2015, p3468 - 3478Journal Article, 2015, DOI , TARA - Full Text
• Knapik J, Wojnarowska Z, Grzybowska K, Jurkiewicz K, Tajber L, Paluch M, Molecular dynamics and physical stability of coamorphous ezetimib and indapamide mixtures, Molecular Pharmaceutics, 12, (10), 2015, p3610 - 3619Journal Article, 2015, DOI , TARA - Full Text
• Serrano DR, Mugheirbi NA, O'Connell P, Leddy N, Healy AM, Tajber L, Impact of substrate properties on the formation of spherulitic films: a case study of salbutamol sulfate, Crystal Growth and Design, 16, (7), 2016, p3853 - 3858Journal Article, 2016, DOI , URL , TARA - Full Text
• Umerska A, Corrigan OI, Tajber L, Design of chondroitin sulfate-based polyelectrolyte nanoplexes: Formation of nanocarriers with chitosan and a case study of salmon calcitonin, Carbohydrate Polymers, 156, 2017, p276 - 284Journal Article, 2017, DOI , URL , TARA - Full Text
• Wlodarski K, Tajber L, Sawicki W., Physicochemical properties of direct compression tablets with spray dried and ball milled solid dispersions of tadalafil in PVP-VA, European Journal of Pharmaceutics and Biopharmaceutics, 109, 2016, p14 - 23Journal Article, 2016, DOI , TARA - Full Text
• Mesallati H, Mugheirbi NA, Tajber L, Two faces of ciprofloxacin: investigation of proton transfer in solid state transformations, Crystal Growth and Design, 16, (11), 2016, p6574 - 6585Journal Article, 2016, DOI , TARA - Full Text
• Knapik J, Wojnarowska Z, Grzybowska K, Tajber L, Mesallati H, Paluch K, Paluch M, Molecular dynamics and physical stability of amorphous nimesulide drug and its binary drug-polymer systems, Molecular Pharmaceutics, 13, (6), 2016, p1937 - 1946Journal Article, 2016, DOI , TARA - Full Text
• Mugheirbi N, Fleischer K, Tajber L, A rare case of mesomorphic behavior-molecular reorientation of itraconazole liquid crystal induced by a hygrothermal treatment, Crystal Growth and Design, 16, (3), 2016, p1329 - 1336Journal Article, 2016, DOI , TARA - Full Text
• Borges VRA, Tavares M, Silva JH, Tajber L, Boylan F, Ribeiro A, Nasciuti LE, Cabral L, Sousa VP, Development and characterization of poly(lactic-co-glycolic) acid nanoparticles loaded with copaiba oleoresin, Pharmaceutical Development and Technology , 23, (4), 2018, p343 - 350Journal Article, 2018, DOI
• Tajber L, Corrigan OI, Healy AM, Physicochemical evaluation of PVP-thiazide diuretic interactions in co-spray-dried composites-analysis of glass transition composition relationships, European Journal of Pharmaceutical Sciences, 24, (5), 2005, p553 - 563Journal Article, 2005, DOI
• Tajber L, Kocot A, Vij JK, Merkel K, Zalewska-Rejdak J, Mehl GH, Elsasser R, Goodby JW, Veith M, Orientational order and dynamics of nematic multipodes based on carbosilazane cores using optical and dielectric spectroscopy, Macromolecules, 35, (22), 2002, p8601 - 8608Journal Article, 2002, DOI
• Jastrzebska M, Kocot A, Tajber L, Photoconductivity of synthetic dopa-melanin polymer , Journal of Photochemistry and Photobiology B: Biology, 66, (3), 2002, p201 - 206Journal Article, 2002, DOI
• Mesallati H, Umerska A, Paluch KJ, Tajber L, Amorphous polymeric drug salts as ionic solid dispersion forms of ciprofloxacin, Molecular Pharmaceutics, 14, 2017, p2209 - 2223Journal Article, 2017, DOI , TARA - Full Text
• Dul M, Paluch KJ, Healy AM, Sasse A, Tajber L, Optimisation of the self-assembly process: production of stable, alginate-based polyelectrolyte nanocomplexes with protamine, Journal of Nanoparticle Research, 19, (6), 2017, p221 - 231Journal Article, 2017, DOI , TARA - Full Text
• Mesallati H, Tajber L, Polymer/amorphous salt solid dispersions of ciprofloxacin, Pharmaceutical Research, 34, (11), 2017, p2425 - 2439Journal Article, 2017, DOI , TARA - Full Text
• Mesallati H, Conroy D, Hudson S, Tajber L, Preparation and characterization of amorphous ciprofloxacin-amino acid salts, European Journal of Pharmaceutics and Biopharmaceutics, 121, 2017, p73 - 89Journal Article, 2017, DOI , TARA - Full Text
• Paluch KJ, Tajber L, McCabe T, O'Brien JE, Corrigan OI, Healy AM, Crystal structure of chlorothiazide sodium, Refcode APUZER, CCDC Number 757605 , CCDC, https://www.ccdc.cam.ac.uk/, 2009Dataset, 2009, DOI
• Paluch KJ, Tajber L, McCabe T, O'Brien JE, Corrigan OI, Healy AM, Crystal structure of chlorothiazide potassium, Refcode APUZIV, CCDC Number 761198, CCDC, https://www.ccdc.cam.ac.uk/, 2010Dataset, 2010, DOI
• Paluch KJ, Tajber L, McCabe T, O'Brien JE, Corrigan OI, Healy AM, Crystal structure of chlorothiazide potassium ethanolate, Refcode APUZOB, CCDC Number 761199, CCDC, https://www.ccdc.cam.ac.uk/, 2010Dataset, 2010, DOI
• Paluch KJ, Tajber L, Elcoate CJ T, Corrigan OI, Lawrence SE, Healy AM, Crystal structure of salbutamol adipate, Refcode ORUWUU, CCDC Number 801059, CCDC, https://www.ccdc.cam.ac.uk/, 2010Dataset, 2010, DOI
• Paluch KJ, Tajber L, Elcoate CJ T, Corrigan OI, Lawrence SE, Healy AM, Crystal structure of salbutamol succinate methanolate, Refcode ORUXAB, CCDC Number 801060, CCDC, https://www.ccdc.cam.ac.uk/, 2010Dataset, 2010, DOI
• Paluch KJ, McCabe T, Müller-Bunz H, Corrigan OI, Healy AM, Tajber L, Crystal structure of ciprofloxacin succinate, Refcode QABTOF, CCDC Number 870867, CCDC, https://www.ccdc.cam.ac.uk/, 2012Dataset, 2012, DOI
• Paluch KJ, McCabe T, Müller-Bunz H, Corrigan OI, Healy AM, Tajber L, Crystal structure of ciprofloxacin succinate, Refcode QABTUL, CCDC Number 870866, CCDC, https://www.ccdc.cam.ac.uk/, 2012Dataset, 2012, DOI
• Wojnarowska Z, Paluch KJ, Shoifet E, Schick C, Tajber L, Knapik J, Wlodarczyk P, Grzybowska K, Hensel-Bielowka S, Verevkin SP, Paluch M, Crystal structure of lidocaine succinate, Refcode ROYWIN, CCDC Number 935179, CCDC, https://www.ccdc.cam.ac.uk/, 2013Dataset, 2013, DOI
• Wojnarowska Z, Paluch KJ, Shoifet E, Schick C, Tajber L, Knapik J, Wlodarczyk P, Grzybowska K, Hensel-Bielowka S, Verevkin SP, Paluch M, Crystal structure of lidocaine phosphate, Refcode ROYWOT, CCDC Number 935178, CCDC, https://www.ccdc.cam.ac.uk/, 2013Dataset, 2013, DOI
• Salt Forms: Pharmaceutical Aspects in, editor(s)James Swarbrick , Encyclopedia of Pharmaceutical Technology, CRC Press, 2013, pp3041 - 3051, [Corrigan OI, Tajber L]Book Chapter, 2013, DOI
• Mugheirbi N, O'Connell P, Serrano D, Healy AM, Taylor L, Tajber L, A comparative study on the performance of inert and functionalized spheres coated with solid dispersions made of two structurally related antifungal drugs, Molecular Pharmaceutics, 14, 2017, p3718 - 3728Journal Article, 2017, DOI , TARA - Full Text
• Hanah Mesallati, The production and characterization of fluoroquinolone amorphous solid dispersions, Trinity College Dublin, 2017Thesis, 2017, URL
• Naila Mugheirbi , Engineering of itraconazole nano- and micro-particles with improved pharmaceutical performance, Trinity College Dublin, 2016Thesis, 2016
• Joanne Crean, The optimisation, characterisation and platelet compatibility of polymeric nanocarriers loaded with NSAIDs, Trinity College Dublin, 2014Thesis, 2014, URL
• Anita Umerska, Formulation and characterisation of polyelectrolyte complex nanoparticles for the delivery of salmon calcitonin, Trinity College Dublin, 2013Thesis, 2013, URL
• Maria Dul, Engineering a novel insulin delivery system , Trinity College Dublin, 2013Thesis, 2013, URL
• Lidia Tajber, Investigations of physicochemical properties of spray dried drug-excipient composites directed to inhalable products, Trinity College Dublin, 2005Thesis, 2005, URL
• Christine Grossjohann, Pharmaceutical cocrystals: a contribution to fundamental studies addressing solubility, dissolution, formation and characterisation, Trinity College Dublin, 2013Thesis, 2013, URL
• Evelyn O'Shea, Investigation of the solid-state, powder flow and tabletability properties of comminuted active pharmaceutical ingredients, Trinity College Dublin, 2013Thesis, 2013
• Stefano Bianco, The effect of processing on the solid state characteristics of selected sulphonamides and their sodium salts, alone and as drug-salt composites, Trinity College Dublin, 2013Thesis, 2013, URL
• Maria Ines Amaro, Development of salmon calcitonin (sCT) nanoporous/nanoparticulate microparticles for pulmonary delivery, Trinity College Dublin, 2013Thesis, 2013, URL
• Krzysztof Jan Paluch, Solid-state characteristics of pre and post-spray dried active pharmaceutical ingredients, salts and co-crystalline forms, Trinity College Dublin, 2011Thesis, 2011, URL
• Xue Li, Formulation, production and biointeraction of micro and nano-particulates with potential for use in drug delivery, Trinity College Dublin, 2009Thesis, 2009, URL
• Svenja Sladek, Polymer-based polyelectrolyte nanocomplexes for oral and intra-articular peptide delivery, University College Dublin, 2017Thesis, 2017
• Tajber L, Healy AM, Corrigan OI, The effect of polyvinylpyrrolidone content on the glass transition temperature of thiazide diuretics, International Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Nuremberg, Germany, 15-18 March, 2004, 2004, pp711 - 712Meeting Abstract, 2004
• Corrigan O, Tajber L, Ryan S, Brayden D, Umerska A, 'A polymeric nanoparticle', University College Dublin, US20140038894, 2011Patent, 2011, URL
• Healy AM, McDonald B, Corrigan OI, Tajber L, 'A method of producing porous microparticles', Trinity College Dublin, US20100092453, 2007Patent, 2007, URL
• Ni Ogain O, Tajber L, Corrigan OI, Healy AM, Nanoporous microparticles (NPMPs) - a novel drug delivery system for the pulmonary delivery of proteins, AAPS Journal, American Association of Pharmaceutical Scientists Annual Meeting, San Antonio, TX, US, 29/10-2/11, 2006, 8, (S2), 2006Meeting Abstract, 2006
• McDonald BF, Tajber L, Corrigan OI, Healy AM, Nanoporous microparticles (NPMPs) of budesonide for pulmonary delivery, AAPS Journal, American Association of Pharmaceutical Scientists Annual Meeting, San Antonio, TX, US, 29/10-2/11, 2006, 8, (S2), 2006Meeting Abstract, 2006
• Amaro MI, Tewes F, Tajber L, Corrigan OI, Healy AM, Characterisation, aerodynamic behaviour and bioactivity of salmon calcitonin-loaded nanoporous/nanoparticulate microparticles (NPMPs), FIP Pharmaceutical Sciences World Congress (PSWC) in association with the AAPS Annual Meeting and Exposition, New Orleans, USA, 14-18, November 2010, 2010Meeting Abstract, 2010
• Tewes F, Gobbo OL, Tajber L, Corrigan OI, Ehrhardt C, Healy AM, Effect of PEG type and HPβCD on salmon calcitonin biopharmaceutical properties following pulmonary delivery , FIP Pharmaceutical Sciences World Congress (PSWC) in association with the AAPS Annual Meeting and Exposition, New Orleans, USA, 14-18 November, 2010, 2010Meeting Abstract, 2010
• Gobbo OL, Tewes F, Swaminathan J, Baginski L, Amaro MI, Umerska AM, Corrigan OI, Tajber L, Healy AM, Ehrhardt C, Comparative in vivo evaluation of different delivery systems for the pulmonary administration of salmon calcitonin , FIP Pharmaceutical Sciences World Congress (PSWC) in association with the AAPS Annual Meeting and Exposition, New Orleans, USA, 14-18 November, 2010, 2010Meeting Abstract, 2010
• Amaro MI, Tajber L, Corrigan OI, Healy AM, Design of experiment to study the effect of spray dryer operating variables on sugar powders intended for inhalation, UKPharmSci, APS, the Science of Medicines, Nottingham, UK, 1-3 September, 2010, 2010Meeting Abstract, 2010
• Caron V, Tajber L, Corrigan OI, Healy AM, Production and characterisation of sulfonamide/polyvinylpyrrolidone amorphous dispersions prepared by ball milling, UKPharmSci, APS, the Science of Medicines, Nottingham, UK, 1-3 September, 2010, 2010Meeting Abstract, 2010
• Caron V, Tajber L, Corrigan OI, Healy AM, Production of amorphous dispersions of sulfonamides/polyvinylpyrrolidone by ball milling, UKPharmSci, APS, the Science of Medicines, Nottingham, UK, 1-3 September, 2010, 2010Meeting Abstract, 2010
• Paluch KJ, Tajber L, Corrigan OI, Healy AM, Investigation of physicochemical interactions of spray dried composites comprising polymer and chlorothiazide, chlorothiazide sodium or chlorothiazide potassium, UKPharmSci, APS, the Science of Medicines, Nottingham, UK, 1-3 September, 2010, 2010Meeting Abstract, 2010
• Curtin V, Caron V, Tajber L, Corrigan OI, Healy AM, Transformation of crystalline sulfadimidine and mannitol upon milling and co-milling, 9th International Workshop on Crystal Growth of Organic Materials, Singapore, 4-7 August, 2010, 2010Oral Presentation, 2010
• Grossjohann C, L Tajber L, Corrigan OI, Healy AM, Co-crystal engineering of sulfadimidine by co-grinding in the solid state, 9th International Workshop on Crystal Growth of Organic Materials, Singapore, 4-7 August, 2010, 2010Meeting Abstract, 2010
• Amaro MI, Tewes F, Tajber L, Corrigan OI, Healy AM, Formulation and stability of sugar-based salmon calcitonin-loaded nanoporous/nanoparticulate microparticles (NPMPs) for inhalation, Journal of Aerosol Medicine and Pulmonary Drug Delivery, 18th Congress of the International Society for Aerosols in Medicine (ISAM), Rotterdam, 18-22 June, 2011, 24, 2011, ppA1 - A66Conference Paper, 2011, DOI
• Tewes F, Gobbo OL, Tajber L, Corrigan OI, Ehrhardt C, Healy AM, PEG-based microparticles for pulmonary administration of salmon calcitonin, Journal of Aerosol Medicine and Pulmonary Drug Delivery, 18th Congress of the International Society for Aerosols in Medicine (ISAM), Rotterdam, 18-22 June, 2011, 24, 2011, ppA1 - A66Conference Paper, 2011, DOI
• Hibbitts A, Sivadas N, Tewes F, Healy AM, Tajber L, Ehrhardt C, Cryan SA, MacLoughlin R, Investigation of fluid physicochemical properties on output in vibrating mesh nebulisers, Journal of Aerosol Medicine and Pulmonary Drug Delivery, 18th Congress of the International Society for Aerosols in Medicine (ISAM), Rotterdam, 18-22 June, 2011, 24, 2011, ppA1 - A66Conference Paper, 2011, DOI
• Ryan SM, Patel H, Kornerup KN, Tajber L, Umerska A, Perretti M, Brayden DJ, Intra-articular delivery of salmon calcitonin nanocomplexes to the K/BxN murine model for treatment of osteoarthritis, European Society for Biomaterials Annual Conference in Dublin, Dublin, 4-9 September, 2011, 2011Oral Presentation, 2011
• Amaro MI, Tewes F, Tajber L, Corrigan OI, Healy AM, Physicochemical, physical stability and aerosolisation properties of trehalose/cyclodextrin microparticles, AAPS Annual Meeting and Exposition, Washington, USA, 23-27 October, 2011, 2011Meeting Abstract, 2011
• Crean J, Endter S, Corrigan OI, Radomski M, Tajber L, Poly-lactide-co-glycolide (PLGA) and hyaluronic acid-chitosan (HACS) nanoparticles (NPs) loaded with ketoprofen: a comparison of their effect on inhibition of platelet aggregation , AAPS Annual Meeting and Exposition, Washington, USA, 23-27 October, 2011, 2011Meeting Abstract, 2011
• Tewes F, Tajber L, Ehrhardt C, Healy AM, Formulation of colistin-ambroxol microparticles for passive targeting of lung infection, AAPS Annual Meeting and Exposition, Washington, USA, 23-27 October, 2011, 2011Meeting Abstract, 2011
• Caron V, Tajber L, Corrigan OI, Healy AM, Production of sulphonamide/PVP and sulphonamide/Soluplus® amorphous dispersions by ball milling: Construction of physical stability diagrams, AAPS Annual Meeting and Exposition, Washington, USA, 23-27 October, 2011, 2011Meeting Abstract, 2011
• Bianco S, Tewes F, Caron V, Tajber L, Corrigan OI, Healy AM, Modification of the solid state of sulfathiazole-sulfathiazole sodium composite systems via spray drying, AAPS Annual Meeting and Exposition, Washington, USA, 23-27 October, 2011, 2011Meeting Abstract, 2011
• Umerska AM, Corrigan OI, Tajber L , Preparation and characterisation of salmon calcitonin loaded hyaluronate-based nanoparticles, UK and Ireland Controlled Release Society Symposium, Belfast, 13 April, 2011, 2011Meeting Abstract, 2011
• Crean J, Endter S, Tajber L, Inhibition of platelet aggregation by PLGA nanoparticles loaded with non-steroidal anti-inflammatory drugs , UK and Ireland Controlled Release Society Symposium, Belfast, 13 April, 2011, 2011Meeting Abstract, 2011
• Curtin V, Caron V, Tajber L, Corrigan OI, Healy AM, The impact of co-milling sulfadimidine with low glass transition temperature excipients as a strategy for preventing process induced amorphisation, UK and Ireland Controlled Release Society Symposium, Belfast, 13 April, 2011, 2011Meeting Abstract, 2011
• Bianco S, Caron V, Tajber L, Corrigan OI, Healy AM, Alteration of the solid state nature of sulfathiazole and sulfathiazole sodium on spray drying, UK and Ireland Controlled Release Society Symposium, Belfast, 13 April, 2011, 2011Meeting Abstract, 2011
• Knapik-Kowalczuk J, Wojnarowska Z, Chmiel K, Rams-Baron M, Tajber L, Paluch M., Can Storage Time Improve the Physical Stability of Amorphous Pharmaceuticals with Tautomerization Ability Exposed to Compression? The Case of a Chloramphenicol Drug., Molecular Pharmaceutics, 15, (5), 2018, p1928 - 1940Journal Article, 2018, DOI
• McComiskey KPM, Mugheirbi NA, Stapleton J, Tajber L., In Situ Monitoring of Nanoparticle Formation: Antisolvent Precipitation of Azole Anti-fungal Drugs., International Journal of Pharmaceutics, 543, (1-2), 2018, p201 - 213Journal Article, 2018, DOI , TARA - Full Text
• Mugheirbi NA, O'Connell P, Serrano DR, Healy AM, Taylor LS, Tajber L, A Comparative Study on the Performance of Inert and Functionalized Spheres Coated with Solid Dispersions Made of Two Structurally Related Antifungal Drugs, Molecular Pharmaceutics, 14, (11), 2017, p3718-3728Journal Article, 2017, DOI , URL
• Inkielewicz-Stepniak I, Tajber L, Behan G, Zhang H, Radomski MW, Medina C, Santos-Martinez MJ, The Role of Mucin in the Toxicological Impact of Polystyrene Nanoparticles, Materials, 11, (5), 2018, p1 - 12Journal Article, 2018, DOI , TARA - Full Text
• Inkielewicz-Stepniak, I. and Tajber, L. and Behan, G. and Zhang, H. and Radomski, M.W. and Medina, C. and Santos-Martinez, M.J., The role of mucin in the toxicological impact of polystyrene nanoparticles, Materials, 11, (5), 2018, p724-Journal Article, 2018, DOI , URL , TARA - Full Text
• Sladek S, Kearney C, Crean D, Brama PAJ , Tajber L, Fawcett K, Labberte MC, Leggett B, Brayden DJ, Intra-articular delivery of a nanocomplex comprising salmon calcitonin, hyaluronic acid, and chitosan using an equine model of joint inflammation, Drug Delivery and Translational Research, 8, (5), 2018, p1421 - 1435Journal Article, 2018, DOI , TARA - Full Text
• McComiskey K, Tajber L, Comparison of particle size methodology and assessment of nanoparticle tracking analysis (NTA) as a tool for live monitoring of crystallisation pathways, European Journal of Pharmaceutics and Biopharmaceutics, 130, 2018, p314 - 326Journal Article, 2018, DOI , TARA - Full Text
• Umerska A, Paluch KJ, Santos-Martinez MJ, Corrigan OI, Medina C, Tajber L, Freeze drying of polyelectrolyte complex nanoparticles: Effect of nanoparticle composition and cryoprotectant selection, International Journal of Pharmaceutics, 552, (1-2), 2018, p27 - 38Journal Article, 2018, DOI , TARA - Full Text
• Kozyra A, Mugheirbi NA, Paluch KJ, Garbacz G, Tajber L, Phase diagrams of polymer-dispersed liquid crystal systems of itraconazole - component immiscibility induced by molecular anisotropy, Molecular Pharmaceutics, 15, (11), 2018, p5192 - 5206Journal Article, 2018, DOI , TARA - Full Text
• Wojnarowska Z, Smolka W, Zotova J, Knapik-Kowalczuk J, Sherif A, Tajber L, Paluch M, The Effect of Electrostatic Interactions on the Formation of Pharmaceutical Eutectics, Physical Chemistry Chemical Physics, 20, (43), 2018, p27361 - 27367Journal Article, 2018, DOI
• Amharar Y, Tajber L, Corrigan OI, Healy AM, Amorphisation of crystalline APIs by dry mixing, AAPS Annual Meeting and Exposition, Chicago, USA, 14-18 October, 2012, 2012Meeting Abstract, 2012
• Paluch KJ, Tajber L, Adamczyk B, Corrigan OI, Healy AM, Continuous crystallisation by spray drying to produce nanocrystalline microparticle (NCMP) powders with enhanced tabletability performance, AAPS Annual Meeting and Exposition, Chicago, USA, 14-18 October, 2012, 2012Meeting Abstract, 2012
• Dul M, Kelly H, Tajber L, Development of a new nanoparticulate system for the oral delivery of insulin, AAPS Annual Meeting and Exposition, Chicago, USA, 14-18 October, 2012, 2012Meeting Abstract, 2012
• Grossjohann C, Paluch KJ, Coakley N, Tajber L, Corrigan OI, Healy AM, Investigating the potential for reaction crystallization on spray-drying sulfadimidine with aromatic carboxylic acids, AAPS Annual Meeting and Exposition, Chicago, USA, 14-18 October, 2012, 2012Meeting Abstract, 2012
• Curtin V, Amharar Y, Hu Y, McArdle P, Erxleben A, Caron V, Tajber L, Corrigan OI, Healy AM, Investigation of the capability of crystalline dicarboxylic acids to minimize amorphization of sulfadimidine on co-milling, AAPS Annual Meeting and Exposition, Chicago, USA, 14-18 October, 2012, 2012Meeting Abstract, 2012
• Paluch KJ, McCabe T, Mueller-Bunz H, Corrigan OI, Healy AM, Tajber L, Supersaturation of drug in aqueous media obtained by transformation of ciprofloxacin succinate hydrate, AAPS Annual Meeting and Exposition, Chicago, USA, 14-18 October, 2012, 2012Meeting Abstract, 2012
• Paluch KJ, Tajber L, Corrigan OI, Healy AM, Assessment of compactibility performance of spray dried, amorphous and excipient-free, large surface area nanoporous microparticles, 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, Turkey, 19-22 March, 2012, 2012Meeting Abstract, 2012
• Crean J, Corrigan OI, Tajber L, Exploring hydrophobic drug interaction with polyelectrolyte complex nanoparticles, 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, Turkey, 19-22 March, 2012, 2012Meeting Abstract, 2012
• Umerska AM, Inkielewicz-Stepniak I, Corrigan OI, Medina C, Tajber L, Redispersibility studies on freeze-dried hyaluronic acid/chitosan polymeric nanoparticles, 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, Turkey, 19-22 March, 2012, 2012Meeting Abstract, 2012
• Grossjohann C, Tajber L, Corrigan OI, Healy AM, Co-grinding and co-spray drying: alternative approaches to the formation of cocrystals, 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, Turkey, 19-22 March, 2012, 2012Meeting Abstract, 2012
• Curtin V, Corcoran S, Hu Y, McArdle P, Erxleben A, Caron V, Tajber L, Corrigan OI, Healy AM, The capability of glutaric acid excipient to improve the crystallinity of sulfadimidine and salbutamol sulphate upon co-milling, 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, Turkey, 19-22 March, 2012, 2012Meeting Abstract, 2012
• Amaro MI, Gobbo O, Tewes F, Tajber L, Corrigan OI, Ehrhardt C, Healy AM, Characterisation and pharmacokinetic studies of salmon calcitonin:sugar nanoporous/nanoparticulate microparticles (NPMPs) for pulmonary delivery, 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, Turkey, 19-22 March, 2012, 2012Meeting Abstract, 2012
• Paluch KJ, Corrigan OI, Healy AM, Tajber L, Preparation and characterisation of novel solid state forms of ciprofloxacin with dicarboxylic acids, 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, Turkey, 19-22 March, 2012, 2012Meeting Abstract, 2012
• Paluch KJ, McCabe T, Mueller-Bunz H, Corrigan OI, Healy AM, Tajber L, Drug supersaturation through a water mediated transformation of salts - studies on ciprofloxacin succinate, 10th International Workshop on Crystal Growth of Organic Materials CGOM, Limerick, Ireland, 11-14 June, 2012, 2012Meeting Abstract, 2012
• Bianco S, Tewes F, Tajber L, Caron V, Corrigan OI, Healy AM, Bulk and surface properties and water uptake mechanisms of salt/acid amorphous composite systems, 10th International Workshop on Crystal Growth of Organic Materials CGOM, Limerick, Ireland, 11-14 June, 2012, 2012Meeting Abstract, 2012
• Amharar Y, Tajber L, Corrigan OI, Healy AM, Mechanical activation of crystalline APIs by dry blending, 10th International Workshop on Crystal Growth of Organic Materials CGOM, Limerick, Ireland, 11-14 June, 2012, 2012Meeting Abstract, 2012
• Crean J, Paluch KJ, Corrigan OI, Tajber L, The solid state of hydrophobic drugs in polyelectrolyte nanoplexes, 10th International Workshop on Crystal Growth of Organic Materials CGOM, Limerick, Ireland, 11-14 June, 2012, 2012Meeting Abstract, 2012
• Grossjohann C, Tajber L, Corrigan OI, Healy AM, Physicochemical properties, solubility and dissolution of a cocrystal composed of two amphoteric components, 10th International Workshop on Crystal Growth of Organic Materials CGOM, Limerick, Ireland, 11-14 June, 2012, 2012Meeting Abstract, 2012
• Paluch KJ, Tajber L, Adamczyk B, Corrigan OI, Healy AM, Continuous crystallisation of nanodispersible microparticles by spray drying for improved tableting, 10th International Workshop on Crystal Growth of Organic Materials CGOM, Limerick, Ireland, 11-14 June, 2012, 2012Meeting Abstract, 2012
• Curtin V, Hu Y, McArdle P, Erxleben A, Caron V, Tajber L, Corrigan OI, Healy AM, Use of a low glass transition temperature excipient to minimise amorphisation of salbutamol sulphate and sulfadimidine upon co-milling, 10th International Workshop on Crystal Growth of Organic Materials CGOM, Limerick, Ireland, 11-14 June, 2012, 2012Meeting Abstract, 2012
• O'Shea E, Tajber L, Corrigan OI, Healy AM, Comminution of sulfathiazole polymorphs, 10th International Workshop on Crystal Growth of Organic Materials CGOM, Limerick, Ireland, 11-14 June, 2012, 2012Meeting Abstract, 2012
• Dul M, Kelly H, Sasse A, Tajber L, Formulation and in vitro characterisation of polymeric nanoparticulate carrier systems for oral delivery of insulin, 5th World Conference on Drug Absorption, Transport and Delivery: Clinical Significance and Regulatory Impact, Uppsala, Sweden , 24-26 June, 2013, 2013Meeting Abstract, 2013
• Kozyra A, Colgan DA, Paluch KJ, Tajber L, Ionic liquids of lidocaine with dicarboxylic acids, 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbon, Portugal, 31 March-3 April, 2014Meeting Abstract, 2014
• Mugheirbi N, Paluch KJ, Tajber L, Heat induced evaporative antisolvent nanoprecipitation of itraconazole, 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbon, Portugal, 31 March-3 April, 2014Meeting Abstract, 2014
• Paluch KJ, Wojnarowska Z, Żeglinski J, Knapik J, Paluch M, Healy AM, Tajber L, The role of thermodynamic and kinetic fragility in the stabilisation of amorphous nimesulide composites, 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbon, Portugal, 2014Meeting Abstract, 2014
• Mugheirbi NA, Tajber L, Evaporative antisolvent precipitation of enteric itraconazole nanoparticles, UK and Ireland Controlled Release Society Symposium, Cork, Ireland, 31 March-3 April, 2014Meeting Abstract, 2014
• Sladek S, Tajber L, Brayden DJ, Self-assembling hyaluronate-based polyelectrolyte nanocomplexes for oral insulin delivery, 41st Annual Meeting & Exposition of the Controlled Release Society, Chicago, USA, 13-16 July, 2014 , 2014Meeting Abstract, 2014
• Brennan C, Tian Y, Paluch KJ, Tajber L, Andrews G, Healy AM, Drug-polymer thermodynamic phase diagrams in the selection of optimal API-polymer compositions for amorphous solid dispersions, AAPS Annual Meeting and Exposition, San Diego, USA, 2-6 November, 2014, 2014Meeting Abstract, 2014
• Mugheirbi N, Tajber L, Tailoring itraconazole crystal habits-impact of solvent and polymer effect, AAPS Annual Meeting and Exposition, San Diego, USA, 2-6 November, 2014, 2014Meeting Abstract, 2014
• Wlodarski K, Sawicki W, Tajber L, Paluch M, Is thermodynamic solubility of tadalafil in Kollidon® VA 64 the key parameter affecting physical stability of the amorphous solid dispersion?, 1st European Conference on Pharmaceutics: Drug Delivery, Reims, France, 13-14 April, 2015, 2015Meeting Abstract, 2015
• Sladek S, Eskander M, Tajber L, Brayden DJ, Size exclusion chromatography: a useful method to determine peptide loading of nanoparticles, 42nd Annual Meeting & Exposition of the Controlled Release Society, Edinburgh, Scotland, 26-29 July, 2015, 2015Meeting Abstract, 2015
• Kozyra A, Paluch KJ, Tajber L, Application of theoretical and practical approaches in the prediction of itraconazole-polymer miscibility for the design of solid dispersions, AAPS Annual Meeting and Exposition, Orlando, USA, 25-29 October, 2015, 2015Meeting Abstract, 2015
• McComiskey K, Mugheirbi N, Tajber L, In situ monitoring of kinetics of azole anti-fungal nanoparticle formation, AAPS Annual Meeting and Exposition, Orlando, USA, 25-29 October, 2015, 2015Meeting Abstract, 2015
• Mugheirbi L, Tajber L, Mesophase and size manipulation of itraconazole liquid crystalline nanoparticles produced via quasi nano-emulsion precipitation, AAPS Annual Meeting and Exposition, Orlando, USA, 25-29 October, 2015, 2015Meeting Abstract, 2015
• Mesallati H, Tajber L, Production of binary amorphous salt solid dispersions of ciprofloxacin, AAPS Annual Meeting and Exposition, Orlando, USA, 25-29 October, 2015, 2015Meeting Abstract, 2015
• Mugheirbi L, Tajber L, Unusual isomorphic intergrowth of itraconazole induced by tuning recrystallization conditions, AAPS Annual Meeting and Exposition, Orlando, USA, 25-29 October, 2015, 2015Meeting Abstract, 2015
• Sladek S, Eskander M, Tajber L, Brayden DJ, Hyaluronate-based polyelectrolyte nanocomplexes as a potential oral peptide delivery formulation, Crossing Biological Barriers - Advances in Nanocarrier Design for Targeted Drug Delivery (DECHEMA), Dresden, Germany, 9-11 November, 2015, 2015Meeting Abstract, 2015
• Mugheirbi NA, Umerska A, Tajber L, Trojan microparticles containing ciprofloxacin nanoparticles produced via media milling, 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Glasgow, UK, 4-7 April, 2016, 2016Meeting Abstract, 2016
• Wlodarski K, Tajber L, Sawicki W, Direct compression of amorphous spray dried and ball milled tadalafil/PVP-VA solid dispersions, 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Glasgow, UK, 4-7 April, 2016, 2016Meeting Abstract, 2016
• Mesallati H, Conroy D, Tajber L, Preparation of amorphous solid dispersions of the zwitterionic drug ciprofloxacin with amino acids, 51st AAPS Arden Conference, Baltimore, USA, 18-20 April, 2016, 2016Meeting Abstract, 2016
• McDonagh A, Tajber L, The crystallisation of active pharmaceutical ingredients onto excipient surfaces using a spray dryer, 12th International Workshop on Crystal Growth of Organic Materials CGOM, Leeds, UK, 26-20 June, 2016, 2016Meeting Abstract, 2016
• Cruz R, Bowe R, Santos-Martinez MJ, Tajber L, Investigation of interactions of pegylated and non-pegylated itraconazole nanoparticles with mucin using quartz crystal microbalance with dissipation and dynamic light scattering, AAPS Annual Meeting and Exposition, San Diego, USA, 12-15 November, 2017, 2017Meeting Abstract, 2017
• Mugheirbi N, Tajber L, Taylor L, Investigations into the dissolution process of amorphous solid dispersions: an orthogonal approach utilizing high resolution imaging coupled with localized thermal analysis, AAPS Annual Meeting and Exposition, San Diego, USA, 12-15 November, 2017, 2017Meeting Abstract, 2017
• McDonagh A, Brennan L, Tajber L, Investigation of the physical properties of drug-excipient tablets comprising powders produced by co-spray drying, AAPS Annual Meeting and Exposition, San Diego, USA, 12-15 November, 2017, 2017Meeting Abstract, 2017
• McComiskey K, Tajber L, Critical comparison of dynamic light scattering versus nanoparticle tracking analysis as particle sizing techniques and solid state monitoring for azole anti-fungal nanodispersions, AAPS Annual Meeting and Exposition, San Diego, USA, 12-15 November, 2017, 2017Meeting Abstract, 2017
• McComiskey K, Mugheirbi N, Stapleton J, Tajber L, In situ monitoring of azole anti-fungal nanoparticle formation, AAPS Annual Meeting and Exposition, San Diego, USA, 12-15 November, 2017, 2017Meeting Abstract, 2017
• Mugheirbi N, Zotova J, Umerska AM, Santos-Martinez MJ, Tajber L, Novel surfactant-stabilized ciprofloxacin nanodispersions made by media milling; interactions with physiological barriers using quartz crystal microbalance with dissipation monitoring, AAPS Annual Meeting and Exposition, San Diego, USA, 12-15 November, 2017, 2017Meeting Abstract, 2017
• Bialek K, Wojnarowska Z, Tajber L, Formation of eutectic and multicomponent phases of propranolol, 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Granada, Spain, 19-22 March, 2018, 2018Meeting Abstract, 2018
• Zotova J, Sherif A, Wojnarowska Z, Tajber L, Eutectic, deep eutectic and other multicomponent phases of lidocaine with dicarboxylic acids, 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Granada, Spain, 19-22 March, 2018, 2018Meeting Abstract, 2018
• Wojnarowska Z, Paluch M, Tajber L, Role of intermolecular interactions in the formation of pharmaceutical eutectics, 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Granada, Spain, 19-22 March, 2018, 2018Meeting Abstract, 2018
• Sladek S, Healy AM, Tajber L, Thermally-induced aggregation behaviour of liquid protein formulations at low concentrations as determined by DLS and NTA, 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Granada, Spain, 19-22 March, 2018, 2018Meeting Abstract, 2018
• Bialek K, Wojnarowska Z, Tajber L, Formation of eutectic and multicomponent phases of propranolol, 1st International Conference on Contemporary Pharmacy Challenges: Amorphous Pharmaceuticals and Biopharmaceuticals, Wisla, Poland, 9-11 September, 2018, 2018Meeting Abstract, 2018
• Paczkowska M, Bialek K, McDonagh A, Cielecka-Piontek J, Tajber L, Evaluation of physicochemical and tableting properties of rutin-cyclodextrin complexes, Acta Pharmaceutica Hungarica, 12th Central European Symposium on Pharmaceutical Technology and Regulatory Affairs, Szeged, Hungary, 20-22 September 2018, 88, (3), 2018, pp184 - 185Conference Paper, 2018
• Paczkowska M, Tajber L, Cielecka-Piontek J, Application of PAMPA gastrointestinal model to predict permeability of sumatriptan in free form and in system with cyclodextrin derivatives, Acta Pharmaceutica Hungarica, 12th Central European Symposium on Pharmaceutical Technology and Regulatory Affairs, Szeged, Hungary, 20-22 September 2018, 88, (3), 2018, pp194 - 195Conference Paper, 2018
• Bialek K, Wojnarowska Z, Tajber L, Formation and Characterisation of a New Salt, Di-Propranolol Sebacate, Chemical Crystallography @ Central Facilities, Belfast, NI, 31 October, 2018, 2018Meeting Abstract, 2018
• Wojnarowska Z, Tajber L, Paluch M, Density Scaling in Ionic Glass-Former Controlled by Grotthuss Conduction, Journal of Physical Chemistry B, 123, (5), 2019, p1156 - 1160Journal Article, 2019, DOI , TARA - Full Text
• Brennan C, A. Giles A, Amaro MI, Tajber L, Andrews GP, Healy AM, Film Casting as a Screening Technique in the Selection of API-Polymer Compositions for Amorphous Solid Dispersion Production via Spray Drying, Controlled Release Society Annual Meeting 2015, Edinburgh, UK, 26-29 July, 2015, 2015Meeting Abstract, 2015
• Wojnarowska Z, Zotowa J, Knapik-Kowalczuk J, Tajber L, Paluch M, Effect of electrostatic interactions on the relaxation dynamics of pharmaceutical eutectics, European Journal of Pharmaceutical Sciences, 134, 2019, p93 - 101Journal Article, 2019, DOI , TARA - Full Text
• McComiskey KPM, McDonagh AF, Tajber L, Isolation of Itraconazole Nanostructured Microparticles via Spray Drying with Rational Selection of Optimum Base for Successful Reconstitution and Compaction, AAPS PharmSciTech, 20, (5), 2019, p217-Journal Article, 2019, DOI
• Mesallati H, Umerska A, Tajber L, Fluoroquinolone Amorphous Polymeric Salts and Dispersions for Veterinary Uses, Pharmaceutics, 11, (6), 2019, pE268-Journal Article, 2019, DOI
• Nanoparticle Tracking Analysis to Examine the Temperature-Induced Aggregation of Proteins in, editor(s)McManus, J.J. , Protein Self-Assembly: Methods and Protocols , New York, Humana Press, 2019, pp131 - 139, [Sladek S., McComiskey K., Healy A.M., Tajber L.]Book Chapter, 2019, DOI
• McComiskey, K.P.M. and Mugheirbi, N.A. and Stapleton, J. and Tajber, L., In situ monitoring of nanoparticle formation: Antisolvent precipitation of azole anti-fungal drugs, International Journal of Pharmaceutics, 543, (1-2), 2018, p201-213Journal Article, 2018, DOI , URL
• Wojnarowska, Z. and Smolka, W. and Zotova, J. and Knapik-Kowalczuk, J. and Sherif, A. and Tajber, L. and Paluch, M., The effect of electrostatic interactions on the formation of pharmaceutical eutectics, Physical Chemistry Chemical Physics, 20, (43), 2018, p27361-27367Journal Article, 2018, DOI , URL , TARA - Full Text
• Mugheirbi, N.A. and Fleischer, K. and Tajber, L., A Rare Case of Mesomorphic Behavior-Molecular Reorientation of Itraconazole Liquid Crystal Induced by a Hygrothermal Treatment, Crystal Growth and Design, 16, (3), 2016, p1329-1336Journal Article, 2016, DOI , URL
• Amaro, M.I. and Tajber, L. and Corrigan, O.I. and Healy, A.M., Co-Spray dried carbohydrate microparticles: Crystallisation delay/inhibition and improved aerosolization characteristics through the incorporation of hydroxypropyl-β-cyclodextrin with amorphous raffinose or trehalose, Pharmaceutical Research, 32, (1), 2015, p180-195Journal Article, 2015, DOI , URL
• StojkoviÄ , A. and Tajber, L. and DjuriÄ , Z. and Corrigan, O.I. and ParojÄ iÄ , J., In vitro simulation of drug interaction: Ciprofloxacin/zinc chloride, Journal of Drug Delivery Science and Technology, 24, (2), 2014, p229-233Journal Article, 2014, DOI , URL
• Knapik-Kowalczuk J, Gündüz MG, Chmiel K, Jurkiewicz K, Kurek M, Tajber L, Jachowicz R, Paluch M., Molecular dynamics, viscoelastic properties and physical stability studies of a new amorphous dihydropyridine derivative with T-type calcium channel blocking activity., European Journal of Pharmaceutical Sciences, 141, 2020, p105083Journal Article, 2020, DOI
• McDonagh AF, Tajber L, Crystallo-co-spray drying as a new approach to manufacturing of drug/excipient agglomerates: impact of processing on the properties of paracetamol and lactose mixtures., International Journal of Pharmaceutics, 2020, p119051Journal Article, 2020, DOI , TARA - Full Text
• Machado Cruz R, Santos-Martinez MJ, Tajber L., Impact of polyethylene glycol polymers on the physicochemical properties and mucoadhesivity of itraconazole nanoparticles., European Journal of Pharmaceutics and Biopharmaceutics, 144, 2019, p57 - 67Journal Article, 2019, DOI
• McDonagh AF, Tajber L, The control of paracetamol particle size and surface morphology through crystallisation in a spray dryer, Advanced Powder Technology, 31, 2020, p287 - 299Journal Article, 2020, DOI
• Umerska A, Mugheirbi N, Kasprzak A, Saulnier P, Tajber L, Carbohydrate-based Trojan microparticles as carriers for pulmonary delivery of lipid nanocapsules using dry powder inhalation, Powder Technology, 364, 2020, p507 - 521Journal Article, 2020, DOI , TARA - Full Text
• Paczkowska M, McDonagh AF, Bialek K, Tajber L, Cielecka-Piontek J, Mechanochemical activation with cyclodextrins followed by compaction as an effective approach to improving dissolution of rutin, International Journal of Pharmaceutics, 581, 2020, p119294Journal Article, 2020, DOI , TARA - Full Text
• Umerska A, Sapin-Minet A, Parent M, Tajber L, Maincent P, Boudier A, Understanding the Thermodynamic Mechanisms Leading to the Binding of Albumin to Lipid Nanocapsules, Langmuir, 36, (15), 2020, p4165 - 4173Journal Article, 2020, DOI
• Sladek S, McCartney F, Eskander M, Dunne DJ, Santos-Martinez MJ, Benetti F, Tajber L, Brayden DJ., An Enteric-Coated Polyelectrolyte Nanocomplex Delivers Insulin in Rat Intestinal Instillations when Combined with a Permeation Enhancer., Pharmaceutics, 12, (3), 2020Journal Article, 2020, DOI , TARA - Full Text
• Umerska A, Bialek K, Zotova J, Skotnicki M, Tajber L., Anticrystal Engineering of Ketoprofen and Ester Local Anesthetics: Ionic Liquids or Deep Eutectic Mixtures?, Pharmaceutics, 12, (4), 2020Journal Article, 2020, DOI , TARA - Full Text
• Jakubowska E, Davin S, Dumicic AD, Garbacz G, Juppo A, Michniak-Kohn B, Rudzki PJ, Smułek W, Strachan C, Syarkevych O, Tajber L, Lulek J, ORBIS (Open Research Biopharmaceutical Internships Support) - building bridges between academia and pharmaceutical industry to improve drug development, Journal of Medical Science, 89, (1), 2020, pe419Journal Article, 2020, DOI
• Knapik-Kowalczuk J, Chmiel K, Pacułt J, Bialek K, Tajber L, Paluch M, Enhancement of the Physical Stability of Amorphous Sildenafil in a Binary Mixture, with either a Plasticizing or Antiplasticizing Compound, Pharmaceutics, 12, (5), 2020, p460Journal Article, 2020, DOI , TARA - Full Text
• McDonagh AF, Duff B, Brennan L, Tajber L., The impact of the degree of intimate mixing on the compaction properties of materials produced by crystallo-co-spray drying , European Journal of Pharmaceutical Sciences, 154, (1), 2020, p105505Journal Article, 2020, DOI , TARA - Full Text
• Machado Cruz R, Boleslavská T, Beránek J, Tieger E, Twamley B, Santos-Martinez MJ, Dammer O, Tajber L., Identification and Pharmaceutical Characterization of a New Itraconazole Terephthalic Acid Cocrystal , Pharmaceutics, 12, (8), 2020, pE741Journal Article, 2020, DOI , TARA - Full Text
• Zotova J, Wojnarowska Z, Twamley B, Paluch P, Tajber L., Green Synthesis of Lidocaine Ionic Liquids and Salts: Mechanisms of Formation and Interactions in the Crystalline and Supercooled States, ACS Sustainable Chemistry & Engineering, 8, (49), 2020, p18266 - 1827Journal Article, 2020, DOI , TARA - Full Text
• Skotnicki M, Jadach B, Skotnicka A, Milanowski B, Tajber L , Pyda M, Kujawski J, Physicochemical Characterization of a Co-Amorphous Atorvastatin-Irbesartan System with a Potential Application in Fixed-Dose Combination Therapy , Pharmaceutics, 13, (1), 2021, p118Journal Article, 2021, DOI , TARA - Full Text
• Bialek K, Wojnarowska Z, Twamley B, Tajber L., Characterisation and fundamental insight into the formation of new solid state, multicomponent systems of propranolol., International Journal of Pharmaceutics, 602, 2021, p120605Journal Article, 2021, DOI , TARA - Full Text
• Chmiel K, Knapik-Kowalczuk J, Kaminska E, Tajber L, Paluch M, High-Pressure Dielectric Studies-a Way to Experimentally Determine the Solubility of a Drug in the Polymer Matrix at Low Temperatures, Molecular Pharmaceutics, 18, (8), 2021, p3050-3062Journal Article, 2021, DOI , TARA - Full Text
• Umerska A, Zotova J, Tajber L, Formation of low melting point binary systems comprising ketoprofen and an amide local anaesthetic, International Journal of Pharmaceutics, 607, 2021, p120969Journal Article, 2021, DOI , TARA - Full Text
• Zotova J, Wojnarowska Z, Twamley B, Tajber L, Formation of stoichiometric and non-stoichiometric ionic liquid and cocrystal multicomponent phases of lidocaine with azelaic acid by changing counterion ratios, Journal of Molecular Liquids, 344, 2021, p117737Journal Article, 2021, DOI , TARA - Full Text
• Zotova J, Wojnarowska Z, Twamley B, Tajber L, Crystal structure of N-(2,6-dimethylphenyl)-N2,N2-diethylglycinamide hemikis(nonanedioic acid), Refcode DALJIN, CCDC Number 2098381, CCDC, https://www.ccdc.cam.ac.uk/, 2021Dataset, 2021, DOI
• Zotova J, Wojnarowska Z, Twamley B, Tajber L, Crystal structure of bis(2-(2,6-dimethylanilino)-N,N-diethyl-2-oxoethan-1-aminium) nonanedioate bis(nonanedioic acid), Refcode DALJOT, CCDC Number 2098382, CCDC, https://www.ccdc.cam.ac.uk/, 2021Dataset, 2021, DOI
• Bialek K, Wojnarowska Z, Twamley B, Tajber L, Crystal structure of bis{2-hydroxy-3-[(naphthalen-1-yl)oxy]-N-(propan-2-yl)propan-1-aminium} decanedioate, Refcode EROJED, CCDC Number 2049634, CCDC, https://www.ccdc.cam.ac.uk/, 2020Dataset, 2020, DOI
• Zotova J, Wojnarowska Z, Twamley B, Paluch M, Tajber L, Crystal structure of 2-(2,6-dimethylanilino)-N,N-diethyl-2-oxoethan-1-aminium 4-carboxybutanoate, Refcode IVEKEC, CCDC Number 2031291, CCDC, https://www.ccdc.cam.ac.uk/, 2020Dataset, 2020, DOI
• Zotova J, Wojnarowska Z, Twamley B, Paluch M, Tajber L, Crystal structure of 2-(2,6-dimethylanilino)-N,N-diethyl-2-oxoethan-1-aminium 5-carboxypentanoate, Refcode IVEKIG, CCDC Number 2031292, CCDC, https://www.ccdc.cam.ac.uk/, 2020Dataset, 2020, DOI
• Zotova J, Wojnarowska Z, Twamley B, Paluch M, Tajber L, Crystal structure of 2-(2,6-dimethylanilino)-N,N-diethyl-2-oxoethan-1-aminium 6-carboxyhexanoate, Refcode IVEKOM, CCDC Number 2031293, CCDC, https://www.ccdc.cam.ac.uk/, 2020Dataset, 2020, DOI
• Zotova J, Wojnarowska Z, Twamley B, Paluch M, Tajber L, Crystal structure of 2-(2,6-dimethylanilino)-N,N-diethyl-2-oxoethan-1-aminium 7-carboxyheptanoate, Refcode IVEKUS, CCDC Number 2031294, CCDC, https://www.ccdc.cam.ac.uk/, 2020Dataset, 2020, DOI
• Machado Cruz R, Boleslavska T, Beranek J, Tieger E, Twamley B, Santos-Martinez MJ, Dammer O, Tajber L, Crystal structure of 2-(butan-2-yl)-4-(4-{4-[4-({2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan-4-yl}methoxy)phenyl]piperazin-1-yl}phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one hemikis(benzene-1,4-dicarboxylic acid), Refcode UCEBUD, CCDC Number 2015894, CCDC, https://www.ccdc.cam.ac.uk/, 2020Dataset, 2020, DOI
• Bialek K, Wojnarowska Z, Skotnicki M, Twamley B, Paluch M, Tajber L, Submerged Eutectic-Assisted, Solvent-Free Mechanochemical Formation of a Propranolol Salt and Its Other Multicomponent Solids, Pharmaceutics, 13, (12), 2021, p2125Journal Article, 2021, DOI , TARA - Full Text
• Hugo Silva M, Kumar A, Hodnett K, Holm R, Tajber L, Hudson S, Impact of excipients on solid-state form transformation of indomethacin during liquid antisolvent (LAS) precipitation, UKICRS Virtual Symposium 2021, virtual, 13 October, 2021, 2021Meeting Abstract, 2021
• Mendez Canellas F, Padrela L, Tajber L, Geertman R, Verma V, Kujawski J, Control over the α polymorph of indomethacin using a supercritical carbon dioxide-based method, UKICRS Virtual Symposium 2021, virtual, 13 October, 2021, 2021Meeting Abstract, 2021
• Bialek K, Tajber L, The Formation and Characterisation of a Novel Salt and Eutectic Forms of Propranolol with Azelaic Acid, AAPS 2019 PHARMSCI 360, San Antonio, US, 3-6 November, 2019, 2019Meeting Abstract, 2019
• Bialek K, Umerska A, Tajber L, In Situ Crystallisation of Propranolol Salts in an Amorphous Polymeric Matrix Made of Soluplus, AAPS 2019 PHARMSCI 360, San Antonio, US, 3-6 November, 2019, 2019Meeting Abstract, 2019
• Umerska A, Bialek K, Skotnicki M, Zotova J, Tajber L, Development and characterisation of ketoprofen-benzocaine deep eutectic mixtures, AAPS 2019 PHARMSCI 360, San Antonio, US, 3-6 November, 2019, 2019Meeting Abstract, 2019
• Umerska A, Bialek K, Skotnicki M, Zotova J, Tajber L, Development and characterisation of procaine-ketoprofen deep eutectic mixtures, AAPS 2019 PHARMSCI 360, San Antonio, US, 3-6 November, 2019, 2019Meeting Abstract, 2019
• Tajber L, Mesallati H, Zotova J, Wojnarowska Z, Umerska A, "New" solutions to the problem of poorly soluble drugs - the role of "green", anti-crystal engineering, Proceedings, The 1st International Electronic Conference on Pharmaceutics, virtual, 1-15 December, 2020, 4, 2020, ppxConference Paper, 2020, DOI
• Kate McComiskey, The production, characterisation, stabilization and isolation of azole anti-fungal nanoparticles, Trinity College Dublin, 2019Thesis, 2019, URL
• Agnieszka Kozyra, The production and characterisation of itraconazole multicomponent systems, Trinity College Dublin, 2019Thesis, 2019, URL
• Vincent Curtin, Investigatons of the potential of crystalline excipients to prevent the process-induced amorphisation of active pharmaceutical ingredients, Trinity College Dublin, 2014Thesis, 2014, URL
• Alan Francis McDonagh, he production of crystalline powders by spray drying to improve the mechanical and flow properties of an active pharmaceutical ingredient, Trinity College Dublin, 2020Thesis, 2020, URL
• Ricardo Machado Cruz, New solid forms of itraconazole and their pharmaceutical applications, Trinity College Dublin, 2020Thesis, 2020, URL
• Nadhim Kamil Hante, Role of kynurenine on platelet's function and beyond, Trinity College Dublin, 2020Thesis, 2020, URL
• Tajber L, Skotnicki M, Davin S, Voelkel A, Lulek J, Perspectives of manufacturing of active pharmaceutical ingredients and advances in preformulation studies, cordis.europa.eu, 2020, 1-30Report, 2020, URL
• McHugh M, Hayes S, Tajber L, Ryan L, Medicine Maker: An Outreach Activity for Pharmaceutical Manufacturing and Health Literacy., Journal of Chemical Education, 99, (3), 2022, p1231 - 1237Journal Article, 2022, DOI , TARA - Full Text
• Nandi S, Padrela L, Tajber L, Collas A, Nucleation kinetics-based solvent selection for bottom-up generation of nano/micro-suspensions, 13th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Rotterdam, The Netherlands, 28-31 March, 2022, 2022Meeting Abstract, 2022
• Mendez Canellas F, Verma V, Kujawski J, Tajber L, Geertman R, Padrela L, Polymorphic control of indomethacin using a carbon dioxide antisolvent method, 13th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Rotterdam, The Netherlands, 28-31 March, 2022, 2022Meeting Abstract, 2022
• Hugo Silva M, Kumar A, Hodnett K, Holm R, Tajber L, Hudson S, Impact of excipients and seeding on solid-state form transformation of indomethacin during liquid antisolvent (LAS) precipitation, 13th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Rotterdam, The Netherlands, 28-31 March, 2022, 2022Meeting Abstract, 2022
• Kadri L, Tajber L, Solid-state transformations of fluoroquinolone drug levofloxacin via ball milling, 13th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Rotterdam, The Netherlands, 28-31 March, 2022, 2022Meeting Abstract, 2022
• Monteiro MF, Umerska A, Tajber L, Processing a deep eutectic mixture by spray drying to produce a solid form suitable for tableting, 13th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Rotterdam, The Netherlands, 28-31 March, 2022, 2022Meeting Abstract, 2022
• Kramarczyk D, Knapik-Kowalczuk J, Smolka W, Monteiro MF, Tajber L, Paluch M, Inhibition of celecoxib crystallization by mesoporous silica - Molecular dynamics studies leading to the discovery of the stabilization origin., European Journal of Pharmaceutical Sciences, 171, 2022, p106132Journal Article, 2022, DOI
• Hugo Silva M, Hudson SP, Tajber L, Garin M, Dong W, Khamiakova T, Holm R, Osmolality of Excipients for Parenteral Formulation Measured by Freezing Point Depression and Vapor Pressure - A Comparative Analysis. , Pharmaceutical Research, 2022Journal Article, 2022, DOI
• Zotova J, Twamley B, Tajber L, Impact of the Dicarboxylic Acid Chain Length on Intermolecular Interactions with Lidocaine, Molecular Pharmaceutics, 19, (8), 2022, p2980-2991Journal Article, 2022, DOI
• Taylor LS, Braun DE, Tajber L, Steed JW, Crystallizing the Role of Solid-State Form in Drug Delivery, Molecular Pharmaceutics, 19, (8), 2022, p2683-2685Journal Article, 2022, DOI
• Beraldo-Araújo VL, Flávia Siqueira Vicente A, van Vliet Lima M, Umerska A, Souto EB, Tajber L, Oliveira-Nascimento L., Levofloxacin in nanostructured lipid carriers: Preformulation and critical process parameters for a highly incorporated formulation., International journal of pharmaceutics, 626, 2022, p122193Journal Article, 2022, DOI
• Cañellas FM, Verma V, Kujawski J, Geertman R, Tajber L, Padrela L., Controlling the Polymorphism of Indomethacin with Poloxamer 407 in a Gas Antisolvent Crystallization Process., ACS Omega, 7, (48), 2022, p43945-43957Journal Article, 2022, DOI
• Mendez Canellas F., Geertman R., Tajber L., Padrela L., Sorbitol-coated indomethacin and naproxen particles produced by supercritical CO2-assisted spray drying, Journal of Supercritical Fluids, 199, 2023, p105969-Journal Article, 2023, DOI
• Nandi S., Padrela L., Tajber L., Collas A., Development of long-acting injectable suspensions by continuous antisolvent crystallization: An integrated bottom-up process, International Journal of Pharmaceutics, 648, 2023, p123550-Journal Article, 2023, DOI
• Garbiec E., Rosiak N., Zalewski P., Tajber L., Cielecka-Piontek J., Genistein Co-Amorphous Systems with Amino Acids: An Investigation into Enhanced Solubility and Biological Activity, Pharmaceutics, 15, (12), 2023, p2653-Journal Article, 2023, DOI
• Mendez Canellas F., Al-Rifai N., Padrela L., Tajber L., Khamiakova T., Otava M., Geertman R., A comparative study of dry and wet top-down milling approaches for the preparation of microparticle suspensions, Powder Technology, 428, 2023, p118829-Journal Article, 2023, DOI
• Paczkowska-Walendowska M., Tajber L., Miklaszewski A., Cielecka-Piontek J., Hot Melt Extrusion for Improving the Physicochemical Properties of Polydatin Derived from Polygoni cuspidati Extract; A Solution Recommended for Buccal Applications, Pharmaceuticals, 16, (9), 2023, p1226-Journal Article, 2023, DOI
• Nandi S., Padrela L., Tajber L., Collas A., Nucleation kinetics-based solvent selection for the liquid antisolvent crystallization of a lipophilic intermediate, Journal of Molecular Liquids, 375, 2023, p121306-Journal Article, 2023, DOI
• Dudek M.K., Trzeciak K., Tajber L., Zajac J., Kazmierski S., Pindelska E., Makowski T., Svyntkivska M., Potrzebowski M.J., A New Look at the Mechanism of Cocrystal Formation and Coformers Exchange in Processes Forced by Mechanical and/or Thermal Stimuli " ex situ and in situ Studies of Low-Melting Eutectic Mixtures, Chemistry - A European Journal, 30, (11), 2024, pe202302138-Journal Article, 2024, DOI
• Tajber L, Corrigan OI, Healy AM, Spray drying of budesonide, formoterol fumarate and their composites-II. Statistical factorial design and in vitro deposition properties, International Journal of Pharmaceutics, 367, (1-2), 2009, p86 - 96Journal Article, 2009, DOI
• Tajber L, Corrigan DO, Corrigan OI, Healy AM, Spray drying of budesonide, formoterol fumarate and their composites-I. Physicochemical characterisation, International Journal of Pharmaceutics, 367, (1-2), 2009, p79 - 85Journal Article, 2009, DOI
• Nolan L, Tajber L, Corrigan OI, Healy AM, The physicochemical characterisation of spray dried nanoporous microparticles (NPMPs) of sulfa compounds, EUFEPS Conference: When Poor Solubility Becomes an Issue: From Early Stage to Proof of Principles, Verona, Italy, 26-27 April, 2006, 2006Meeting Abstract, 2006
• Tajber L, Crean B, Roberts CJ, Nolan L, Corrigan OI, Healy AM, Budesonide Nanoporous Microparticles (NPMPs) - in vitro Aerosolisation Properties and Atomic Force Microscopy (AFM), 35th Controlled Release Society Annual Meeting & Exposition, New York, USA, 12-16, July 2008, 2008Meeting Abstract, 2008
• Paluch K, Tajber L, Healy AM, Corrigan OI, Comparison of the physico-chemical properties of spray dried chlorothiazide, chlorothiazide sodium and their PVP composite systems, 6th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Barcelona, Spain, 1-10, April 2008, 2008Meeting Abstract, 2008
• Katheri AK, Tajber L, Corrigan OI, Healy AM, Spray dried nanoporous microparticles of corticosteroids for dry powder oral inhalation, 6th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Barcelona, Spain, 1-10, April 2008, 2008Meeting Abstract, 2008
• Healy AM, McDonald BF, Tajber L, Corrigan OI, Characterisation of excipient-free nanoporous microparticles (NPMPs) of bendroflumethiazide , European Journal of Pharmaceutics and Biopharmaceutics , 69, (3), 2008, p1182 - 1186Journal Article, 2008, DOI
• Nolan LM, Tajber L, McDonald BF, Barham AS, Corrigan OI, Healy AM , Excipient-free nanoporous microparticles of budesonide for pulmonary delivery, European Journal of Pharmaceutics and Biopharmaceutics, 37, (5), 2009, p593 - 602Journal Article, 2009, DOI
• Xue L, Radomski A, Corrigan OI, Tajber L, de Souza Menezes F, Endter S, Medina C, Radomski M, Platelet compatibility of PLGA, chitosan and PLGA-chitosan nanoparticles, Nanomedicine, 4, (7), 2009, p735 - 746Journal Article, 2009, DOI
• Paluch KJ, Tajber L, Corrigan OI, Healy AM, An investigation of the effect of spray drying from different solvents on the physicochemical properties of chlorothiazide and chlorothiazide sodium, AAPS Annual Meeting and Exposition, Los Angeles, USA, 8-12 November, 2009, 2009Meeting Abstract, 2009
• Bianco S, Caron V, Tajber L, Corrigan OI, Healy AM, Physico-chemical characterisation of spray dried sulphonamide compounds and their sodium salts, AAPS Annual Meeting and Exposition, Los Angeles, USA, 8-12 November, 2009, 2009Meeting Abstract, 2009
• O'Shea E, Caron V, Tajber L, Corrigan OI, Healy AM, The Effect of Mechanical Activation on the Solid-State Nature of Commercially Available Sulfathiazole, AAPS Annual Meeting and Exposition, Los Angeles, USA, 8-12 November, 2009, 2009Meeting Abstract, 2009
• Umerska AM, Corrigan OI, Tajber L, Preparation and characterisation of hyaluronate-based nanoparticulate carriers suitable for oral peptide delivery, AAPS Annual Meeting and Exposition, Los Angeles, USA, 8-12 November, 2009, 2009Meeting Abstract, 2009
• Tewes F, Tajber L, Corrigan OI, Healy AM, Development and characterisation of soluble polymeric particles for pulmonary peptide delivery, AAPS Annual Meeting and Exposition, Los Angeles, USA, 8-12 November, 2009, 2009Meeting Abstract, 2009
• Amaro MI, Tajber L, Corrigan OI, Healy AM , Characterisation of sugar nanoporous/nanoparticulate microparticles (NPMPs) and optimisation of the spray drying process for their production, AAPS Annual Meeting and Exposition, Los Angeles, USA, 8-12 November, 2009, 2009Meeting Abstract, 2009
• Caron V, Bianco S, Tajber L, Corrigan OI, Healy AM , Influence of processing on solid state forms of sulphonamide compounds and their mixtures with PVP, AAPS Annual Meeting and Exposition, Los Angeles, USA, 8-12 November, 2009, 2009Meeting Abstract, 2009
• Paluch K, Tajber L, Zarys metod charakterystyki fizykochemicznej układów amorficznych produkowanych metodą suszenia rozpyłowego (Physicochemical methods of characterisation of amorphous materials produced by spray drying - an outline), Farmacja Polska, 65, (2), 2009, p93 - 99Review Article, 2009, URL
• Tewes F, Tajber L, Corrigan OI, Ehrhardt C, Healy AM, Development and characterisation of soluble polymeric particles for pulmonary peptide delivery, European Journal of Pharmaceutical Sciences, 41, (2), 2010, p337 - 352Journal Article, 2010, DOI , URL , TARA - Full Text
• Paluch KJ, Tajber L, McCabe T, O'Brien JE, Corrigan OI, Healy AM, Preparation and solid state characterisation of chlorothiazide sodium intermolecular self assembly suprastructure, European Journal of Pharmaceutical Sciences, 41, (5), 2010, p603 - 611Journal Article, 2010, DOI , URL , TARA - Full Text
• Paluch KJ, Tajber L, McCabe T, O'Brien JE, Corrigan O, Healy AM, Preparation and characterisation of novel chlorothiazide potassium solid-state salt forms: intermolecular self assembly suprastructures, European Journal of Pharmaceutical Sciences, 42, (3), 2011, p220 - 229Journal Article, 2011, DOI , URL , TARA - Full Text
• Ní Ógáin O, Li J, Tajber L, Corrigan OI, Healy AM, Particle engineering of materials for oral inhalation by dry powder inhalers. I - Particles of sugar excipients (trehalose and raffinose) for protein delivery, International Journal of Pharmaceutics, 405, (1-2), 2011, p23 - 35Journal Article, 2011, DOI , URL , TARA - Full Text
• Nolan LM, Li J, Tajber L, Corrigan OI, Healy AM, Particle engineering of materials for oral inhalation by dry powder inhalers. II - Sodium cromoglicate, International Journal of Pharmaceutics, 405, (1-2), 2011, p36 - 46Journal Article, 2011, DOI , URL , TARA - Full Text
• Caron V, Tajber L, Corrigan OI, Healy AM, A comparison of spray drying and milling in the production of amorphous dispersions of sulfathiazole/polyvinylpyrrolidone and sulfadimidine/polyvinylpyrrolidone, Molecular Pharmaceutics, 8, (2), 2011, p532 - 542Journal Article, 2011, DOI
• Paluch K, Tajber L, Elcoate CJ, Corrigan OI, Lawrence SE, Healy AM, Solid state characterisation of novel active pharmaceutical ingredients: co-crystal of a salbutamol hemiadipate salt with adipic acid (2:1:1) and salbutamol hemisuccinate salt, Journal of Pharmaceutical Sciences, 100, (8), 2011, p3268 - 3283Journal Article, 2011, DOI , URL , TARA - Full Text
• Amaro MI, Tajber L, Corrigan OI, Healy AM, Optimisation of spray drying process conditions for sugar nanoporous microparticles (NPMPs) intended for inhalation, International Journal of Pharmaceutics, 421, (1), 2011, p99 - 109Journal Article, 2011, DOI , URL , TARA - Full Text
• Grossjohann C, Eccles KS, Maguire AR, Lawrence SE, Tajber L, Corrigan OI, Healy AM, Characterisation, solubility and intrinsic dissolution behaviour of benzamide:dibenzyl sulfoxide cocrystal, International Journal of Pharmaceutics, 422, (1-2), 2012, p24-32Journal Article, 2012, DOI , URL , TARA - Full Text
• Parojcic J, Stojkovic A, Tajber L, Grbic S, Paluch KJ, Djuric Z, Corrigan OI., Biopharmaceutical characterization of ciprofloxacin HCl-ferrous sulfate interaction, Journal of Pharmaceutical Sciences, 100, (12), 2011, p5174 - 5184Journal Article, 2011, DOI
• Tewes F, Gobbo OL, Amaro MI, Tajber L, Corrigan OI, Ehrhardt C, Healy AM, Evaluation of HPβCD-PEG microparticles for salmon calcitonin administration via pulmonary delivery, Molecular Pharmaceutics, 8, (5), 2011, p1887 - 1898Journal Article, 2011, DOI
• Gad S, Tajber L, Corrigan OI Healy AM, Preparation and characterisation of novel spray dried nano-structured para-aminosalicylic acid particulates for pulmonary delivery: impact of ammonium carbonate on morphology, chemical composition and solid state, Journal of Pharmacy and Pharmacology, 64, (9), 2012, p1264 - 1274Journal Article, 2012, DOI , TARA - Full Text
• Ní Ógáin O, Tajber L, Corrigan OI, Healy AM, Spray drying from organic solvents to prepare nanoporous/nanoparticulate microparticles (NPMPs) of protein:excipient composites designed for oral inhalation, Journal of Pharmacy and Pharmacology, 64, (9), 2012, p1275 - 1290Journal Article, 2012, DOI , TARA - Full Text
• Bianco S, Caron V, Tajber L, Corrigan OI, Nolan LM, Hu Y, Healy AM, Modification of the solid state nature of sulfathiazole and sulfathiazole sodium by spray drying, AAPS PharmSciTech, 13, (2), 2012, p647 - 660Journal Article, 2012, DOI
• Paluch KJ, Tajber L, Corrigan OI, Healy AM, Impact of process variables on the micromeritic and physicochemical properties of spray dried porous microparticles - Part I. Introduction of a new Morphology Classification System, Journal of Pharmacy and Pharmacology, 64, (11), 2012, p1570 - 1582Journal Article, 2012, DOI , TARA - Full Text
• Paluch KJ, Amaro MI, Tajber L, Corrigan OI, Healy AM, Impact of process variables on the micromeritic and physicochemical properties of spray dried microparticles - Part II. Physicochemical characterisation of spray dried materials, Journal of Pharmacy and Pharmacology, 64, (11), 2012, p1583 - 1591Journal Article, 2012, DOI , TARA - Full Text
• Paluch KJ, Tajber L, Adamczyk B, Corrigan OI, Healy AM, A novel approach to crystallisation of nanodispersible microparticles by spray drying for improved tabletability, International Journal of Pharmaceutics, 436, (1-2), 2012, p873 - 876Journal Article, 2012, DOI , URL
• Hu Y, MacFhionnghaile P, Caron V, Tajber L, Healy AM, Erxleben A, Formation, physical stability and quantification of process induced disorder in cryo-milled samples of a model polymorphic drug, Journal of Pharmaceutical Sciences, 102, (1), 2013, p93 - 103Journal Article, 2013, DOI
• Umerska A, Paluch KJ, Inkielewicz-Stępniak I, Santos-Martinez MJ, Corrigan OI, Medina C, Tajber L., Exploring the assembly process and properties of novel crosslinker-free hyaluronate-based polyelectrolyte complex nanocarriers, International Journal of Pharmaceutics, 436, (1-2), 2012, p75 - 87Journal Article, 2012, DOI , URL , TARA - Full Text
• Mori A, Oleszycka E, Sharp FA, Coleman M, Ozasa Y, Singh M, O'Hagan DT, Tajber L, Corrigan OI, McNeela EA, Lavelle EC, The vaccine adjuvant alum inhibits IL-12 by promoting PI3 kinase signaling while chitosan does not inhibit IL-12 and enhances Th1 and Th17 responses., European Journal of Immunology, 42, (10), 2012, p2709 - 2719Journal Article, 2012, DOI
• Tewes F, Paluch KJ, Tajber L, Gulati K, Kalantri D, Ehrhardt C, Healy AM, Steroid/mucokinetic hybrid nanoporous microparticles for pulmonary drug delivery, European Journal of Pharmaceutics and Biopharmaceutics, 85, (3), 2013, p604 - 613Journal Article, 2013, DOI , TARA - Full Text
• Curtin V, Amharar Y, Hu Y, Erxleben A, McArdle P, Caron V, Tajber L, Corrigan OI, Healy AM, Investigation of the capacity of low glass transition temperature excipients to minimize amorphization of sulfadimidine on comilling., Molecular Pharmaceutics, 10, (1), 2013, p386 - 396Journal Article, 2013, DOI
• Caron V, Hu Y, Tajber L, Erxleben A, Corrigan OI, McArdle P, Healy AM, Amorphous solid dispersions of sulfonamide/Soluplus® and sulfonamide/PVP prepared by ball milling., AAPS PharmSciTech, 14, (1), 2013, p464 - 474Journal Article, 2013, DOI
• Ryan SM, McMorrow J, Umerska A, Patel HB, Kornerup KN, Tajber L, Murphy EP, Perretti M, Corrigan OI, Brayden DJ, An intra-articular salmon calcitonin-based nanocomplex reduces experimental inflammatory arthritis., Journal of Controlled Release, 167, (2), 2013, p120 - 129Journal Article, 2013, DOI
• Wojnarowska Z, Kolodziejczyk K, Paluch KJ, Tajber L, Grzybowska K, Ngai KL, Paluch M, Decoupling of conductivity relaxation from structural relaxation in protic ionic liquids and general properties., Physical Chemistry Chemical Physics, 15, (23), 2013, p9205 - 9211Journal Article, 2013, DOI
• Paluch KJ, McCabe T, Müller-Bunz H, Corrigan OI, Healy AM, Tajber L, Formation and physicochemical properties of crystalline and amorphous salts with different stoichiometries formed between ciprofloxacin and succinic acid, Molecular Pharmaceutics, 10, (10), 2013, p3640 - 3654Journal Article, 2013, DOI , TARA - Full Text
• Bianco S, Tewes F, Tajber L, Caron V, Corrigan OI, Healy AM, Bulk, surface properties and water uptake mechanisms of salt/acid amorphous composite systems, International Journal of Pharmaceutics, 456, (1), 2013, p143 - 152Journal Article, 2013, DOI , TARA - Full Text
• Paluch KJ, Tajber L, Corrigan OI, Healy AM, Impact of alternative solid state forms and specific surface area of high-dose, hydrophilic active pharmaceutical ingredients on tabletability, Molecular Pharmaceutics, 10, (10), 2013, p3628 - 3639Journal Article, 2013, URL
• de Sousa VP, Crean J, de Almeida Borges VR, Rodrigues CR, Tajber L, Boylan F, Cabral LM, Nanostructured systems containing babassu (Orbignya speciosa) oil as a potential alternative therapy for benign prostatic hyperplasia., International Journal of Nanomedicine, 8, 2013, p3129 - 3139Journal Article, 2013, DOI , TARA - Full Text
• Curtin V, Amharar Y, Gallagher KH, Corcoran S, Tajber L, Corrigan OI, Healy AM, Reducing mechanical activation-induced amorphisation of salbutamol sulphate by co-processing with selected carboxylic acids, International Journal of Pharmaceutics, 456, (2), 2013, p508 - 516Journal Article, 2013, DOI , TARA - Full Text
• Wojnarowska Z, Grzybowska K, Hawelek L, Dulski M, Wrzalik R, Gruszka I, Paluch M, Pienkowska K, Sawicki W, Bujak P, Paluch KJ, Tajber L, Markowski J, Molecular dynamics, physical stability and solubility advantage from amorphous indapamide drug., Molecular Pharmaceutics, 10, (10), 2013, p3612 - 3627Journal Article, 2013, DOI
• Stojkovic A, Tajber L, Paluch KJ, Djuric Z, Parojcic J, Corrigan OI, Biopharmaceutical characterisation of ciprofloxacin-metallic ion interactions: comparative study into the effect of aluminium, calcium, zinc and iron on drug solubility and dissolution., Acta Pharmaceutica, 64, (1), 2014, p77 - 88Journal Article, 2014, DOI
• Santos-Martinez MJ, Rahme K, Corbalan JJ, Faulkner C, Holmes JD, Tajber L, Medina C, Radomski MW, Pegylation increases platelet biocompatibility of gold nanoparticles., Journal of Biomedical Nanotechnology, 10, (6), 2014, p1004 - 1015Journal Article, 2014, DOI
• Mugheirbi NA, Paluch KJ, Tajber L, Heat induced evaporative antisolvent nanoprecipitation (HIEAN) of itraconazole., International Journal of Pharmaceutics, 471, (1-2), 2014, p400 - 411Journal Article, 2014, DOI , TARA - Full Text
• Wlodarski K, Sawicki W, Paluch KJ, Tajber L, Grembecka M, Hawelek L, Wojnarowska Z, Grzybowska K, Talik E, Paluch M, The influence of amorphization methods on the apparent solubility and dissolution rate of tadalafil., European Journal of Pharmaceutical Sciences, 62, 2014, p132 - 140Journal Article, 2014, DOI
• Amaro MI, Tajber L, Corrigan OI, Healy AM, Co-spray dried carbohydrate microparticles: crystallisation delay/inhibition and improved aerosolization characteristics through the incorporation of hydroxypropyl-ß-cyclodextrin with amorphous raffinose or trehalose, Pharmaceutical Research, 32, (1), 2015, p180 - 195Journal Article, 2015, DOI , TARA - Full Text
• Healy AM, Amaro MI, Paluch KJ, Tajber L, Dry powders for oral inhalation free of lactose carrier particles, Advanced Drug Delivery Reviews, 75, 2014, p32 - 52Review Article, 2014, DOI , TARA - Full Text
• Umerska A, Corrigan OI, Tajber L, Intermolecular interactions between salmon calcitonin, hyaluronate, and chitosan and their impact on the process of formation and properties of peptide-loaded nanoparticles., International Journal of Pharmaceutics, 477, (1-2), 2014, p102 - 112Journal Article, 2014, DOI , TARA - Full Text
• Umerska A, Paluch KJ, Santos-Martinez MJ, Corrigan OI, Medina C, Tajber L, Self-assembled hyaluronate/protamine polyelectrolyte nanoplexes: synthesis, stability, biocompatibility and potential use as peptide carriers, Journal of Biomedical Nanotechnology, 10, (12), 2014, p3658 - 3673Journal Article, 2014, DOI , TARA - Full Text

• Umerska A, Tajber L, Polyelectrolyte complexes as nanoparticulate drug delivery systems, European Pharmaceutical Review, 20, (3), 2015, p36-40Journal Article
• Tajber L, The curious case of ciprofloxacin: how to deal with "difficult" drugs molecules to improve their biopharmaceutical properties, Farmak's School of young scientists "Science and modern pharmaceutical manufacturing", Kiyv, Ukraine, 21 November, 2019, 2019Invited Talk, URL

My research programme concentrates on the fundamental understanding of molecular interactions governing the properties and performance of pharmaceutical substances (actives and additives) at molecular, supramolecular and formulation (drug product) levels. More specifically, the research topics pursued by my group are: . Advancement of the physicochemical and biopharmaceutical properties of active pharmaceutical ingredients (APIs) by conversion into ionic liquids (anti-crystal engineering); development of oral solid formulations containing ionic liquids . Synthesis, phase characterisation and behaviour in formulation of alternative forms of APIs such as salts, cocrystals, amorphous materials, polymorphs and liquid crystals; construction of multi-phase diagrams for stability . Rational preformulation studies leading to quality solid-state formulations . Nanocrystal and polymeric nanoparticle formulation and characterisation methods My research efforts have been supported by Science Foundation Ireland (SFI), Enterprise Ireland, Irish Research Council as well as the European Union. I am involved in the Synthesis and Solid State Pharmaceuticals Centre (https://www.sspc.ie/ ) as a funded investigator. I was awarded a prestigious SFI Career Development Award in 2017 on the development of pharmaceutical ionic liquid forms and also currently serve as Director of Steering Committee in a H2020 RISE network "ORBIS" (Open Research Biopharmaceutical Internships Support (http://orbisproject.eu/ , awarded in 2017). I currently supervise a group of 8 researchers and host visiting ORBIS secondees from the pharmaceutical industry.

• Title

  Synthesis and Solid State Pharmaceutical Centre
  Summary
  Funding Agency

  SFI
  Date From

  2013
  Date To

  2019
• Title

  Active pharmaceutical ingredients as ionic liquids: significance of protonics and functional profiling for the design of effective medicines
  Summary

  A large proportion of pharmaceutical molecules exhibit low aqueous solubility and/or poor membrane transport properties resulting in low oral bioavailability and delivery problems. Thus, many compounds with high pharmacological activity are being dropped from development pipelines. To address the issue of poor solubility and/or permeability of active pharmaceutical ingredients, a new tactic is proposed whereby the active molecule is converted into an ionic liquid (IL), a functional material with superior physicochemical properties to the "parent" molecule. ILs comprise anions and cations and possess low lattice energy and low melting points, often well below 100 °C. Through the systematic investigations of structural properties of ILs, their methods of synthesis, the degree of ionisation and type of proton transport within the ILs as well as extensive pharmaceutical profiling including stability, solubility, permeability and in vitro toxicity, a new generation of ILs with tunable pharmaceutical properties (PILs) will be established. To demonstrate the pharmaceutical developability of PILs and their potential as a platform technology, prototype tablet formulations will be manufactured and tested using novel, bio-relevant dissolution stress test devices. A range of anti-inflammatory and anti-infective molecules will be examined due to their efficacy limitations that are often caused by low solubility and permeability.
  Funding Agency

  SFI
  Date From

  2017
  Date To

  2021
• Title

  Solid State Pharmaceutical Cluster
  Summary
  Funding Agency

  SFI
  Date From

  2007
  Date To

  2013
• Title

  ORBIS
  Summary
  Funding Agency

  European Commission
• Title

  Irish Drug Delivery Network
  Summary
  Funding Agency

  SFI
  Date From

  2007
  Date To

  2013
• Title

  TRANS-INT
  Summary
  Funding Agency

  EU
  Date From

  2012

Pharmacology and pharmaceutical sciences, Nanotechnology, Chemical Sciences, Condensed matter physics,

• Distinction for the Masters thesis in the Master's Degree Dissertations Competition for Faculties of Pharmacy organised by Polish Pharmaceutical Society and Medical Universities 2001
• First prize for the Masters thesis in the Interdepartmental Master's Degree Dissertations Competition 2000
• Elected Fellow of Trinity College Dublin 2020
• M.A. (jure officii) 2015
• Prize from the Czestochowa branch of the Polish Pharmaceutical Chamber for the grades achieved in university degree 2000
• Researcher Highlight in 2018/19 Trinity College Dublin Provost & President's Annual Review 2019
• Trinity College Postgraduate Award 2001

• Controlled Release Society present
• International Association for Pharmaceutical Technology (APV) present
• American Chemical Society present
• American Association of Pharmaceutical Scientists present