Dr. Aisling O'Halloran
Assistant Professor, School of Nursing & Midwifery
Email aiohallo@tcd.ie PhoneBiography
I am currently Assistant Professor in Health Research at the School of Nursing and Midwifery at Trinity College Dublin. Formerly, I was a Senior Research Fellow and Biobank Manager with The Irish Longitudinal Study on Ageing (TILDA) at the School of Medicine, Trinity College Dublin and Mercer"s Institute for Successful Ageing (MISA) at St. James"s Hospital, Dublin. I hold a PhD in the genetic epidemiology of cardiovascular disease from the Royal College of Surgeons in Ireland (RCSI) and a B.A. (Mod) in Natural Science, specializing in genetics, from Trinity College Dublin. My research interests are focused on the biology of the ageing and age-related disease phenotypes including CVD, frailty and disability. My research aims to investigate biomarkers that best capture those who are experiencing accelerated biological ageing and who are therefore at risk for declining health and age-related disease. This information is utilized to inform disease prevention and management strategies, and to improve health and social care policy and service planning. I have published >60 peer-reviewed publications on studies of ageing, epidemiology, molecular biology, immunology, and genetics. As principal or co-investigator, I have received grant funding of €2.1 million from national agencies and international grant funding of €4.5 million (€850,000 to the Irish component) from the US National Institutes of Health. I have taught and supervised undergraduate and postgraduate students to PhD level. Currently, I teach on the Postgraduate Certificate on Advanced Ageing and Frailty Studies at Trinity College Dublin. I am a member of the EUGMS SIG on Frailty and Resilience in Older People, the NIH Biomarker Network, and the Irish Frailty Network. I am associate editor with the journal BMC Geriatrics and served as a member of the national executive committee of the Irish Gerontological Society (2016-2022).
Publications and Further Research Outputs
- Peklar J, O'Halloran AM, Maidment ID, Henman MC, Kenny RA, Kos M. , Sedative load and frailty among community-dwelling population aged ≥65 years. , Journal of the American Medical Directors Association, 16, (4), 2014, p282 - 289Journal Article, 2014, DOI
- Theou O, O'Connell MDL, King-Kallimanis BL, O'Halloran AM, Rockwood K, Kenny RA., Measuring Frailty using Self-report and Test-based Health Measures., Age and Aging, 44, (3), 2015, p471-7Journal Article, 2015, DOI , TARA - Full Text
- Owusu Akuffo K, Nolan J, Stack J,Moran R, Feeney J,Kenny RA, Peto T, Dooley C, O'Halloran AM, Cronin C, and Beatty S. , Prevalence of age-related macular degeneration in the Republic of Ireland. , British Journal of Ophthalmology, 99, 2015, p1037-1044Journal Article, 2015, DOI , TARA - Full Text
- Sweeney T, O'Halloran AM, Hamill RM, Davey GC, Gil M, Southwood OI, Ryan MT., . Novel variation in the FABP3 promoter and its association with fatness traits in pigs., Meat Science, (100), 2014, p32 - 40Journal Article, 2014, DOI
- Leahy S, O' Halloran AM, O' Leary N, Healy M, McCormack M, Kenny RA, O' Connell J., Prevalence and correlates of diagnosed and undiagnosed type 2 diabetes mellitus and pre-diabetes in older adults: Findings from the Irish Longitudinal Study on Ageing (TILDA)., Diabetes research and clinical practice., 110, (3), 2015, p241 - 249Journal Article, 2015, DOI , URL , TARA - Full Text
- Moran R, Nolan J.M, Stack J, O'Halloran A.M, Feeney J, Akuffo K.O, Kenny R.A, Beatty S, Non-dietary correlates and determinants of plasma lutein and zeaxanthin concentrations in the Irish population, The journal of nutrition, health & aging, 21, (3), 2017, p254 - 261Journal Article, 2017, DOI , URL
- Ryan MT, O'Halloran AM, Hamill, RM, Davey, GC, Gil M, Southwood OI, Sweeney T. , Polymorphisms in the regulatory region of the porcine MYLPF gene are related to meat 3 quality traits in the Large White breed., Meat Science, 113, 2016, p104 - 106Journal Article, 2016, DOI , URL
- Murphy C, Shelley E, O Halloran AM, Fahey T, Kenny RA. , Failure to control hypercholesterolaemia in the Irish adult population: Cross-sectional analysis of the baseline wave of The Irish Longitudinal Study on Ageing (TILDA). , Irish Journal of Medical Science, 2017, p1-9Journal Article, 2017, DOI , URL , TARA - Full Text
- Feeney J, O'Leary N, Moran R, O'Halloran AM, Nolan JM, Beatty S, Young IS, Kenny RA. , Plasma Lutein and Zeaxanthin Are Associated With Better Cognitive Function Across Multiple Domains in a Large Population-Based Sample of Older Adults: Findings from The Irish Longitudinal Study on Aging., The journals of gerontology. Series A, Biological sciences and medical sciences, Jan, 2017, p1-6Journal Article, 2017, DOI , URL , TARA - Full Text
- O'Halloran AM, Laird E, Healy M, Moran R, Beatty S, Nolan J, Molloy AM, Kenny RA. , Circulating Blood Biomarkers In Older Adults With Frailty: The Irish Longitudinal Study on Ageing (TILDA)., Age and Ageing, Irish Gerontological Society (IGS) 64th Annual Scientific Meeting, Killarney, Kerry, Ireland, 29 Sept - 1st Oct, 45, (S2), Oxford University Press, 2016, ppii13 - ii56Published Abstract, 2016, DOI , URL
- O'Halloran AM, Laird E, Healy M, Moran R, Beatty S, Nolan J, Molloy AM, Kenny RA., Prevalence Of Micronutrient, Inflammatory Stress, Metabolic And Renal Conditions In Frail Older Adults: The Irish Longitudinal Study on Ageing (TILDA). , Age and Ageing, Irish Gerontological Society (IGS) 64th Annual Scientific Meeting, Killarney, Kerry, Ireland, 29 Sept - 1st Oct, 45, (S2), Oxford University Press, 2016, ppii13 - ii56Published Abstract, 2016, DOI
- Roe L, O'Halloran AM, Normand C., The Evaluation of the Older People Remaining At Home (Oprah) Project: A Mixed Methods Study., Age and Ageing, Irish Gerontological Society (IGS) 64th Annual Scientific Meeting, Killarney, Kerry, Ireland, 29 Sept - 1st Oct, 45, (S2), Oxford University Press, 2016, ppii1 - ii12Published Abstract, 2016, DOI , URL
- Moran R, Nolan J, Stack J, O'Halloran AM, Feeney J, Akuffo KO, Kenny RA, Beatty S. , Relationship Between Prevalence (And Awareness)Of Age-Related Macular Degeneration And Plasma Concentrations Of Lutein And Zeaxanthin In An Older Population., Age and Ageing, Irish Gerontological Society (IGS) 64th Annual Scientific Meeting, Killarney, Kerry, Ireland, 29 Sept - 1st Oct, 45, (S2), Oxford University Press, 2016, ppii13 - ii56Published Abstract, 2016, DOI , URL
- O'Halloran AM, Bressan J, King-Kallimanis BL, O'Connell MDL, Fagan J, Keenan E, Barry J, Kenny RA. , Frailty Is A Marker of Premature Biological Ageing: Preliminary Evidence from The Irish Longitudinal Study of Ageing and a Community-based Methadone Treatment Program., Journal of Frailty and Aging, 3rd International Congress of Frailty and Sarcopenia Research (ICFSR), Boston, USA, 23-25 April, 4, (S1), 2015, pp79-Published Abstract, 2015
- O'Halloran AM, Roe L, Kenny RA and Normand C., The impact of different measures of frailty on rates of health service use among the community dwelling elderly., Journal of Frailty and Aging, 3rd International Congress of Frailty and Sarcopenia Research (ICFSR), Boston, USA, 23-25 April, 4, (S1), 2015, pp46-Published Abstract, 2015
- Roe LD, Normand C, Wren MA, Browne J, O'Halloran AM., The impact of frailty on healthcare utilisation in Ireland: evidence from the Irish Longitudinal Study on Ageing. , BMC Geriatrics, 17, (203), 2017Journal Article, 2017, DOI
- Briggs R, Carey D, O'Halloran A, Kenny RA, Kennelly SP, Validation of the 8-item Centre for Epidemiological Studies Depression Scale in a cohort of community-dwelling older people: data from The Irish Longitudinal Study on Ageing (TILDA), European Geriatric Medicine, 9, (1), 2018, p121-126Journal Article, 2018, DOI , URL , TARA - Full Text
- Fiorito, G., Polidoro, S. Dugue, P.A., Kivimaki, M., Ponzi, E., Matullo, G., Guarrera, S., Assummaa, M.B. Georgiadis, P., Kyrtopoulos, S.O. Krogh, V. Palli, D., Panico, S., Sacerdote, C. Tumino, R., Chadeau-Hyam, M., Stringhini, S., Severi, G., Hodge, A.M., Giles, G.G., Marioni, R., Linnér, R.K. O'Halloran, A., Kenny, R.A., Layte, R., McCrory, C., Baglietto, L., Milne, R.L., Vineis, P. (2017)., Social adversity and epigenetic aging: a multi-cohort study on socioeconomic differences in peripheral blood DNA methylation., Scientific Reports, 7, (1), 2017, p16391 - 16395Journal Article, 2017, DOI , URL , TARA - Full Text
- Moran R, Beatty S, Stack J, O'Halloran AM, Feeney J, Akuffo KO, Peto T, Kenny RA, Nolan JM., The Relationship Between Plasma Concentrations of Lutein and Zeaxanthin with Self-Reported and Actual Prevalence of AMD in an Irish Population-Based Sample., Current eye research, 2017, p383-390Journal Article, 2017, DOI , TARA - Full Text
- O'Halloran AM, Laird EA, Healy M, Moran R, Nolan J et al, CIRCULATING BIOMARKERS PREDICT INCIDENT FRAILTY: THE IRISH LONGITUDINAL STUDY ON AGEING (TILDA) , Innovation in Aging, 21st International Association of Gerontology and Geriatrics (IAGG) World Congress, San Fransisco, 23-27 July 2017, 1, (1 supplemental), Oxford Academic, 2017, pp23 - 23Published Abstract, 2017, DOI
- Donoghue O, Setti A, O'Leary N, O'Halloran AM, Kenny R., SELF-REPORTED UNSTEADINESS PREDICTS FEAR-RELATED ACTIVITY RESTRICTION AT TWO YEARS FOLLOW-UP , Innovation in Aging, 21st International Association of Gerontology and Geriatrics (IAGG) World Congress, San Fransisco, 23-27 July 2017, 1, (1 supplemental), Oxford Academic, 2017, pp927 - 928Published Abstract, 2017, DOI
- Roe LD, O'Halloran AM, Kenny R, Normand C., SUPPORTING OLDER PEOPLE TO AGE IN PLACE IN IRELAND: FRAILTY-RELATED HEALTH CARE USE AND OUTCOMES , Innovation in Aging, 21st International Association of Gerontology and Geriatrics (IAGG) World Congress, San Fransisco, 23-27 July 2017, 1, (1 supplemental), Oxford Academic, 2017, pp1056 - 1056Published Abstract, 2017, DOI
- Laird, E. and O'Halloran, A.M. and Carey, D. and Healy, M. and O'Connor, D. and Moore, P. and Shannon, T. and Molloy, A.M. and Kenny, R.A., The Prevalence of Vitamin D Deficiency and the Determinants of 25(OH)D Concentration in Older Irish Adults: Data from the Irish Longitudinal Study on Ageing (TILDA), Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 73, (4), 2018, p519-525Journal Article, 2018, DOI , URL
- Connolly E, Rhatigan M, O'Halloran AM, Muldrew KA, Chakravarthy U, Cahill M, Kenny RA, Doyle SL., Prevalence of age-related macular degeneration associated genetic risk factors and 4-year progression data in the Irish population, British Journal of Ophthalmology, 102, (12), 2018, p1691 - 1695Journal Article, 2018, DOI , URL
- Laird EJ, O'Halloran AM, Carey D, O'Connor D, Kenny RA, Molloy AM, Voluntary fortification is ineffective to maintain the vitamin B12 and folate status of older Irish adults: evidence from the Irish Longitudinal Study on Ageing (TILDA)., The British journal of nutrition, 2018, p111 - 120Journal Article, 2018, TARA - Full Text
- Briggs R, McCarroll K, O'Halloran A, Healy M, Kenny RA, Laird E, Vitamin D Deficiency Is Associated With an Increased Likelihood of Incident Depression in Community-Dwelling Older Adults., Journal of the American Medical Directors Association, 20, (5), 2019, p517 - 523Journal Article, 2019, DOI , URL , TARA - Full Text
- Wong TY, Massa MS, O'Halloran AM, Kenny RA, Clarke R., Cardiovascular risk factors and frailty in a cross-sectional study of older people: implications for prevention., Age and ageing, 47, (5), 2018, p714-720Journal Article, 2018, DOI , TARA - Full Text
- O'Halloran AM, Laird EJ, Feeney J, Healy M, Moran R, Beatty S, Nolan FM, Molloy AM, Kenny RA. , Circulating micronutrient biomarkers are associated with three measures of frailty: Evidence from The Irish Longitudinal Study on Ageing (TILDA). , JAMDA, 2019Journal Article, 2019, DOI , TARA - Full Text
- Feeney JC, O'Halloran AM, Kenny RA., The Association Between Hair Cortisol, Hair Cortisone, and Cognitive Function in a Population-Based Cohort of Older Adults: Results From The Irish Longitudinal Study on Ageing., The journals of gerontology. Series A, Biological sciences and medical sciences, 75, (2), 2020, p257-265Journal Article, 2020, DOI
- Laird EJ, McNicholas T, O'Halloran AM, Healy M, Molloy AM, Carey D, O'Connor D, McCarroll K, Kenny RA., Vitamin D Status Is Not Associated With Orthostatic Hypotension in Older Adults., Hypertension (Dallas, Tex. : 1979), 74, (3), 2019, p639-644Journal Article, 2019, DOI , TARA - Full Text
- Romero-Ortuno R, Scarlett S, O'Halloran AM, Kenny RA., Is phenotypical prefrailty all the same? A longitudinal investigation of two prefrailty subtypes in TILDA., Age and ageing, 2019Journal Article, 2019, DOI , TARA - Full Text
- Laird E, O'Halloran AM, Fedorowski A, Melander O, Hever A, Sjögren M, Carey D, Kenny RA., Orthostatic hypotension and novel blood pressure associated gene variants in older adults: data from the TILDA Study., The journals of gerontology. Series A, Biological sciences and medical sciences, 2019Journal Article, 2019, DOI , TARA - Full Text
- McCrory C, McLoughlin S, O'Halloran AM, Socio-Economic Position Under the Microscope: Getting 'Under the Skin' and into the Cells, Current Epidemiology Reports, 6, (4), 2019, p403 - 411Journal Article, 2019, DOI , URL
- BMC Geriatrics, Springer Nature, [Associate Editor.], 2018-2020Editorial Board, 2018
- O'Connor DMA, Laird EJ, Carey D, O'Halloran AM, Clarke R, Kenny RA, Molloy AM., Plasma concentrations of vitamin B12 and folate and global cognitive function in an older population: Cross-sectional findings from The Irish Longitudinal Study on Ageing (TILDA)., The British journal of nutrition, 2020, p1-25Journal Article, 2020, DOI
- Ward, M; Turner, N; Briggs, R; O'Halloran, A M; Kenny, R A, Resilience does not mediate the association between Adverse Childhood Experiences and later life depression. Findings from The Irish Longitudinal Study on Ageing (TILDA), Journal of Affective Disorders, 2020Journal Article, 2020, DOI , TARA - Full Text
- McCrory C, Fiorito G, Hernandez B, Polidoro S, O'Halloran AM, Hever A, Ni Cheallaigh C, Lu AT, Horvath S, Vineis P, Kenny RA., GrimAge outperforms other epigenetic clocks in the prediction of age-related clinical phenotypes and all-cause mortality., The Journals of Gerontology. Series A, Biological sciences and medical sciences, 76, (5), 2021, p741 - 749Journal Article, 2021, DOI , TARA - Full Text
- Georgia Richard, Aisling O'Halloran, Paul Doody, Joseph Harbison, Rose Anne Kenny, Roman Romero-Ortuno, Atrial Fibrillation and Acceleration of Frailty: Findings from The Irish Longitudinal Study on Ageing (TILDA), Age and Ageing, 2021Journal Article, 2021, DOI
- McCrory C, Fiorito G, O'Halloran AM, Polidoro S, Vineis P, Kenny RA., Early life adversity and age acceleration at mid-life and older ages indexed using the next-generation GrimAge and Pace of Aging epigenetic clocks., Psychoneuroendocrinology, 137, 2021, p105643Journal Article, 2021, DOI , TARA - Full Text
- O'Connor DMA, Scarlett S, De Looze C, O'Halloran AM, Laird E, Molloy AM, Clarke R, McGarrigle CA, Kenny RA., Low folate predicts accelerated cognitive decline: 8-year follow-up of 3140 older adults in Ireland., European journal of clinical nutrition, 76, (7), 2022, p950 - 957Journal Article, 2022, DOI
- Palina Piankova, Roman Romero-Ortuno, Aisling M O'Halloran, Biomarker Signatures of Two Phenotypical Pre-Frailty Types in The Irish Longitudinal Study on Ageing, Geriatrics (Basel), 2022Journal Article, 2022, DOI , URL , TARA - Full Text
- Kim D.J., Massa M.S., Clarke R, Scarlett S, and O'Halloran A.M., Kenny R.A., and Bennett, D, Variability and agreement of frailty measures and risk of falls, hospital admissions and mortality in TILDA, Scientific Reports, 12, (1), 2022Journal Article, 2022, DOI , TARA - Full Text
- O'Donoghue, P. and O'Halloran, A.M. and Kenny, R.A. and Romero-Ortuno, R., Do the frail experience more adverse events from intensive blood pressure control? A 2-year prospective study in the Irish Longitudinal Study on Ageing (TILDA), eClinicalMedicine, 45, (101304), 2022Journal Article, 2022, DOI , URL
- Eamon Laird and Aisling M. O'Halloran and Anne M Molloy and Martin Healy and Belinda Hernandez and Deirdre O'Connor and Rose Anne Kenny and Robert Briggs, Low vitamin B 12 but not folate is associated with incident depressive symptoms in community-dwelling older adults: a 4-year longitudinal study, British Journal of Nutrition, 2021, p1--22Journal Article, 2021, DOI , TARA - Full Text
- Kevin McCarthy, Eamon Laird, Aisling M. O'Halloran, Padraic Fallon, Deirdre O'Connor, Román Romero Ortuño, Rose Anne Kenny, An examination of the prevalence of metabolic syndrome in older adults in Ireland: Findings from The Irish Longitudinal Study on Ageing (TILDA), PLOS ONE, 2022Journal Article, 2022, DOI
- Caoileann H. Murphy, Eoin Duggan, James Davis, Aisling M. O'Halloran, Silvin P. Knight, Rose Anne Kenny, Sinead N. McCarthy, Roman Romero-Ortuno, Plasma lutein and zeaxanthin concentrations associated with musculoskeletal health and incident frailty in The Irish Longitudinal Study on Ageing (TILDA), Experimental Gerontology, 2022Journal Article, 2022, DOI , TARA - Full Text
- Eoin Duggan, Caoileann H. Murphy, Silvin P. Knight, James R.C. Davis, Aisling M. O'Halloran, Rose Anne Kenny, Roman Romero-Ortuno, Differential Associations Between Two Markers of Probable Sarcopenia and Continuous Orthostatic Hemodynamics in The Irish Longitudinal Study on Ageing, Journal of Gerontology: Medical Sciences, 2022Journal Article, 2022, DOI , TARA - Full Text
- Ward M, Briggs R, McGarrigle CA, De Looze C, O'Halloran AM, Kenny RA., The bi-directional association between loneliness and depression among older adults from before to during the COVID-19 pandemic., International journal of geriatric psychiatry, 38, (1), 2023, pe5856Journal Article, 2023, DOI , TARA - Full Text
- Kevin McCarthy, Eamon Laird, Aisling M. O'Halloran, Padraic Fallon, Román Romero Ortuño, Rose Anne Kenny, Association between metabolic syndrome and risk of both prevalent and incident frailty in older adults: Findings from The Irish Longitudinal Study on Ageing (TILDA), Experimental Gerontology, 2022Journal Article, 2022, DOI , TARA - Full Text
- Peter Hartley, Faye Forsyth, Aisling O'Halloran, Rose Anne Kenny, Roman Romero-Ortuno, Eight-year longitudinal falls trajectories and associations with modifiable risk factors: evidence from The Irish Longitudinal Study on Ageing (TILDA), Age and Ageing, 2023Journal Article, 2023, DOI , TARA - Full Text
- Heike C. Hawerkamp, Adam H. Dyer, Neha D. Patil, Matt McElheron, Niamh O'dowd, Laura O'doherty, Aisling Ui Mhaonaigh, Angel M. George, Aisling M. O'halloran, Conor Reddy, Rose Anne Kenny, Mark A. Little, Ignacio Martin-Loeches, Colm J. Bergin, Sean Kennelly, Seamas C. Donnelly, Nollaig Bourke, Aideen Long, Jacklyn Sui, Derek G. Doherty, Niall Conlon, Cliona Ni Cheallaigh and Padraic Fallon, Characterisation of the Pro-Inflammatory Cytokine Signature in Severe COVID-19, Frontiers in Immunology , 2023Journal Article, 2023
- McCrory, C., McLoughlin, S., Layte, R., Ni Cheallaigh, C., O'Halloran, A.M, Barros, H., Berkman, L.F., Bochud, M., Crimmins, E., Farrell, M., Fraga, S., GrundyE., Kelly-Irving, M., Petrovic, D., Seeman, T., Stringhini, S., Vollenveider, P., Kenny, R.A, Towards a consensus definition of allostatic load: a multi-cohort, multi-system, multi-biomarker individual participant data (IPD ) meta-analysis, Psychoneuroendocrinology, 2023Journal Article, 2023, DOI , TARA - Full Text
- Nowak N, De Looze C, O'Halloran A, Kenny RA, Sexton DJ., The association between kidney function, cognitive function, and structural brain abnormalities in community-dwelling individuals aged 50"+"is mediated by age and biomarkers of cardiovascular disease., Cardiovascular research, 2023, pcvad060Journal Article, 2023, DOI , TARA - Full Text
- Laird Eamon, O'Halloran Aisling M, Molloy Anne M, Healy Martin, Bourke Nollaig, Kenny Rose Anne, Vitamin D status & associations with inflammation in older adults , PloS one , 18 , (6 ), 2023, pe0287169 -Journal Article, 2023, DOI , URL , TARA - Full Text
- Laura Orlandini, Enrica Patrizio, Aisling M O'Halloran, Christine A McGarrigle, Roman Romero Ortuno, Rose Anne Kenny, Marco Proietti, Matteo Cesari, Social vulnerability, frailty and self-perceived health: findings from The Irish Longitudinal Study on Ageing (TILDA), The Journal of Frailty & Aging, 13, (1), 2024, p50 - 56Journal Article, 2024, DOI , TARA - Full Text
- McCarthy K, O'Halloran AM, Fallon P, Kenny RA, McCrory C., Metabolic syndrome accelerates epigenetic ageing in older adults: Findings from The Irish Longitudinal Study on Ageing (TILDA)., Experimental gerontology, 183, 2023, p112314Journal Article, 2023, DOI , TARA - Full Text
- De Looze C, McCrory C, O'Halloran A, Polidoro S, Anne Kenny R, Feeney J., Mind versus body: Perceived stress and biological stress are independently related to cognitive decline., Brain, behavior, and immunity, 115, 2024, p696 - 704Journal Article, 2024, DOI , URL
- Feng Xue, Silvin P. Knight, Emma Connolly, Aisling M. O"Halloran, Morgana Afonso Shirsath, Louise Newman, Eoin Duggan, Rose Anne Kenny, Roman Romero-Ortuno, Were Frailty Identification Criteria Created Equal? A Comparative Case Study on Continuous Non-Invasively Collected Neurocardiovascular Signals during an Active Standing Test in the Irish Longitudinal Study on Ageing (TILDA), Sensors, 24, (2), 2024, p442-Journal Article, 2024, DOI , URL , TARA - Full Text
- O'Halloran A.M., Cremers J., Vrangbaek K., Roe L., Bourke R., Mortensen L.H., Westendorp R.G.J., Kenny R.A., Cardiovascular disease and the risk of incident falls and mortality among adults aged " 65 years presenting to the emergency department: a cohort study from national registry data in Denmark, BMC Geriatrics, 24, (1), 2024Journal Article, 2024, DOI , TARA - Full Text
- Chenhuichen, C. and Oâ Halloran, A.M. and Lang, D. and Kenny, R.A. and Romero-Ortuno, R., The lived experience of frailty: beyond classification and towards a holistic understanding of health, European Geriatric Medicine, 15, (2), 2024, p435 - 444Journal Article, 2024, DOI , URL
- O'Connor D., Molloy A.M., Laird E., Kenny R.A., O'Halloran A.M., Sustaining an ageing population: The role of micronutrients in frailty and cognitive impairment, Proceedings of the Nutrition Society, 2023Journal Article, 2023, DOI
- Mische-Jasmine McKelvie, Sharon Cruise, Mark Ward, Roman Romero-Ortuno, Frank Kee, Rose Anne Kenny, Dermot O"Reilly, Aisling M O"Halloran, Frailty on the island of Ireland: evidence from the NICOLA and TILDA studies, European Journal of Public Health, 34, (4), 2024, p710 - 716Journal Article, 2024, DOI
- Belinda Hernandez, Cathal McCrory, Rose Anne Kenny, Aisling O'Halloran, A Biomarker Signature Associated With Future Functional Decline And Outcomes On The Frailty-Disability Cascade, Age and Ageing, 53, (Supplement_4), Oxford University Press, 2024, ppafae178. 024Conference Paper, 2024, DOI , URL
- Aisling O'Halloran, Healthy Ageing: What Do Our Latest TILDA Studies Show? Lipoprotein (a): Insights from TILDA, 2024Journal Article, 2024, URL
- Deirdre M A O'Connor, Eamon J Laird, Daniel Carey, Aisling M O'Halloran, Robert Clarke, R A Kenny, Anne M Molloy, Plasma concentrations of vitamin B12 and folate and global cognitive function in an older population: cross-sectional findings from The Irish Longitudinal Study on Ageing (TILDA), British Journal of Nutrition, 124, 2020, p602-610Journal Article, 2020, DOI , TARA - Full Text
- Deirdre M. A. O"Connor, Siobhan Scarlett, Céline De Looze, Aisling M. O"Halloran, Eamon Laird, Anne M. Molloy, Robert Clarke , Christine A. McGarrigle and Rose Anne Kenny, Low folate predicts accelerated cognitive decline: 8-year follow-up of 3140 older adults in Ireland, European Journal of Clinical Nutrition, 76, 2022, p950-957Journal Article, 2022, DOI , TARA - Full Text
- Belinda Hernández, Donal Sexton, Frank Moriarty, Niall Cosgrave, Aisling O"Halloran, Christine McGarrigle, Siobhan Scarlett, Rose Anne Kenny, High-risk categories for COVID-19 and their distribution by county in Republic of Ireland-evidence from the TILDA study, April, 2020, 1-32Report, 2020, DOI , TARA - Full Text
- Lorna Roe, Christine McGarrigle, Belinda Hernández, Aisling O"Halloran, Siobhan Scarlett, Mark Ward, Charles Normand, Rose Anne Kenny, Patterns in health service utilisation: Results from Wave 5 of The Irish Longitudinal Study on Ageing, April, 2020, 1-22Report, 2020, DOI , TARA - Full Text
- Aisling O'Halloran, Christine McGarrigle, Siobhan Scarlett, Lorna Roe, Roman Romero-Ortuno and Rose Anne Kenny, TILDA Report on Population Estimates of Physical Frailty in Ireland to Inform Demographics for Over 50s in Ireland during the COVID-19 Pandemic, April, 2020, 1-21Report, 2020, DOI , TARA - Full Text
- Celine De Looze , Cathal McCrory , Aisling O'Halloran , Silvia Polidoro , Rose Anne Kenny, Joanne Feeney, Mind versus body: Perceived stress and biological stress are independently related to cognitive decline, Brain, Behavior, and Immunity, 115, 2024, p696-704Journal Article, 2024, DOI , TARA - Full Text
- Natalia Nowak, George Mellotte, Aisling O'Halloran, Rose Anne Kenny, Donal J Sexton, Chronic Kidney Disease in community-dwelling adults aged 50+ years in Ireland: A Report from TILDA and the National Renal Office, October, 2023, 1-36Report, 2023, TARA - Full Text
- Eamon Laird, Aisling M. O"Halloran, Daniel Carey, Martin Healy, Deirdre O"Connor, Patrick Moore,Tom Shannon, Anne M. Molloy, and Rose Anne Kenny, The Prevalence of Vitamin D Deficiency and the Determinants of 25(OH)D Concentration in Older Irish Adults: Data From The Irish Longitudinal Study on Ageing (TILDA), Journals of Gerontology: Medical Sciences, 73, (4), 2018, p519-525Journal Article, 2018, DOI , TARA - Full Text
- Dolan C, O'Halloran A, Bradley DG, Croke DT, Evans A, O'Brien JK, Dicker P, Shields DC., Genetic stratification of pathogen-response-related and other variants within a homogeneous Caucasian Irish population., European Journal of Human Genetics, 13, (7), 2005, p798 - 806Journal Article, 2005, DOI
- O'Halloran AM, Pénard N, Galli A, Fan CW, Robertson IH, Kenny RA, Falls and falls efficacy: the role of sustained attention in older adults., BMC geriatrics, 11, (85), 2011, p10Journal Article, 2011, DOI , URL , TARA - Full Text
- O'Halloran AM, Fan CW, Kenny RA, Pénard N, Galli A, Robertson IH., Variability in sustained attention and risk of frailty., Journal of the American Geriatric Society, 59, (12), 2011, p2390 - 2392Journal Article, 2011, DOI , URL
- O'Halloran AM, Patterson CC, Horan P, Maree A, Curtin R, Stanton A, McKeown PP, Shields DC., Genetic polymorphisms in platelet-related proteins and coronary artery disease: investigation of candidate genes, including N-acetylgalactosaminyltransferase 4 (GALNT4) and sulphotransferase 1A1/2 (SULT1A1/2)., Journal of Thrombosis and Thrombolysis, 27, (2), 2009, p175 - 184Journal Article, 2009, DOI , URL
- O'Halloran AM, Stanton A, O'Brien E, Shields DC., The impact on coronary artery disease of common polymorphisms known to modulate responses to pathogens., Annals of Human Genetics, 70, (6), 2006, p934 - 945Journal Article, 2006, DOI , URL
- O'Halloran AM, Curtin R, O'Connor F, Dooley M, Fitzgerald A, O'Brien JK, Fitzgerald DJ, Shields DC., The impact of genetic variation in the region of the GPIIIa gene, on Pl expression bias and GPIIb/IIIa receptor density in platelets., British Journal of Haematology, 132, (4), 2006, p494 - 502Journal Article, 2006, DOI , URL
- Shields DC, O'Halloran AM., Integrating genotypic data with transcriptomic and proteomic data., Comparative and Functional Genomics, 3, (1), 2002, p22 - 27Review Article, 2002, DOI , URL , TARA - Full Text
- Ryan MT, Hamill RM, O'Halloran AM, Davey GC, McBryan J, Mullen AM, McGee C, Gispert M, Southwood OI, Sweeney T, SNP variation in the promoter of the PRKAG3 gene and association with meat quality traits in pig., BMC Genetics, 13, (66), 2012, p17Journal Article, 2012, DOI , URL , TARA - Full Text
- O'Halloran AM, Finucane C, Savva GM, Robertson IH, Kenny RA., Sustained Attention and Frailty in the Older Adult Population., Journals of Gerontology B Psychological Sciences and Social Sciences. , 69, (2), 2014, p147 - 155Journal Article, 2014, DOI
- O'Halloran AM, Kenny, RA, King-Kallimanis BL. , The latent factors of depression from the short forms of the CES-D are consistent, reliable and valid in community-living older adults. , European Geriatric Medicine, 5, (2), 2014, 97-102Journal Article, 2014, DOI , TARA - Full Text
- Greene BR, Doheny EP, O'Halloran AM, Kenny RA., Frailty status can be accurately assessed using inertial sensors and the TUG test. , Age and Ageing, 43, (3), 2014, p406 - 411Journal Article, 2014, DOI , URL , TARA - Full Text
- O'Halloran AM, King-Kallimanis BL, O'Connell MDL, Robertson IH, and Kenny RA., Sustained attention correlates with two models of frailty At baseline and follow-up: the irish longitudinal study of ageing., Journal of Frailty and Aging, International Conference of Frailty and Sarcopenia Research, Barcelona, Spain, March 12-14, edited by Cesari M , 3, (1), Serdi Edition, 2014, pp34 - 34Published Abstract, 2014, URL , TARA - Full Text
- Peklar, J, O'Halloran AM, Kos M, Henman MC, Maidment I, Kenny RA, Frailty syndrome and sedative load of drugs, Journal of Frailty and Aging, International Conference on Frailty and Sarcopenia Research, Barcelona, Spain, March 12-14, edited by Cesari M , 3, (1), Serdi Edition, 2014, pp54 - 54Published Abstract, 2014, URL , TARA - Full Text
- O'Halloran, A.M., O'Connell, M.D.L., Finucane, C., Savva, G.M., Robertson, I.H., Kenny, R.A. , The Relationships Between Executive Function, Cognitive Processing Speed And Two Models of Frailty Are Mediated By Sustained Attention In The Older Adult Population. , European Geriatric Medicine, 8th Congress of the European Union Geriatric Medicine Society (EUGMS), Venice, Italy, October 2-4, edited by Michel, J-P , 4, (S1), Elsevier, 2013, ppS70-Published Abstract, 2013, URL , TARA - Full Text
- O'Halloran, A.M., Kallimanis, B.L., Kenny, R.A. , The Impact of Positive Affect on Falls and Fear of Falling in the Older Adult Population. , Age and Ageing, British Geriatric Society (BGS), Annual Meeting, Harrogate, UK, November 28-30, 2012, edited by Stott, DJ , 42, (S2), Oxford Journals, 2013, ppii20-Published Abstract, 2013, URL , TARA - Full Text
- O'Halloran, A.M., Kenny, R.A., King-Kallimanis, B.L., The Factor Structure of the Long and Short Forms of the CES-D Scale and the Validity of Positive Affect in Older Irish Adults., Age and Ageing, British Geriatric Society (BGS), Spring Meeting, Belfast, UK, April 18-19, 2013, edited by Stott, DJ , 45, (S3), Oxford Journals, 2013, ppii27-Published Abstract, 2013, URL , TARA - Full Text
- O'Halloran, A.M., Finucane, C., Savva, G.M., Robertson, I.H., Kenny, R.A. , Sustained Attention Is Associated With Frailty In The Older Adult Population. , European Geriatric Medicine, 8th Congress of the European Union Geriatric Medicine Society (EUGMS), Brussels, Belgium, September 26-28, edited by Michel, J-P , 3, (S1), Serdi Edition, 2012, ppS16-Published Abstract, 2012, URL , TARA - Full Text
- O'Halloran, A.M., Treacy, K., Cunningham, C., Crosby, L., Walsh, C., Fan, C.W., Kenny, R.A. , The Impact of Positive Affect on Falls Efficacy in the Older Adult Population. , European Geriatric Medicine, 8th Congress of the European Union Geriatric Medicine Society (EUGMS), Brussels, Belgium, September 26-28, edited by Michel, J-P , 3, (S1), Serdi Edition, 2012, ppS137-Published Abstract, 2012, URL , TARA - Full Text
- O'Halloran, AM, Recognising Frailty: Insights from The Irish Longitudinal Study on Ageing (TILDA)., : Integrated Care Approach for Frailty in the Older Person Conference. , Galway, Ireland, March 8th , 2017, Health Service Executive and Saolta Hospital Group, 1ppInvited Talk
- Roe L, O'Halloran AM, Normand C, Murphy C., The impact of frailty on public health nurse service utilisation. Findings from The Irish Longitudinal Study on Ageing (TILDA). , Dublin, Ireland, The Irish Longitudinal Study on Ageing., September, 2016, 1-28Report, URL
- O'Halloran AM, Frailty and Falls in Ireland North and South: Preliminary Evidence from TILDA and NICOLA. , Joint Public Health Conference. , Belfast, UK, 8th November, 2018, Public Health Agency Northern Ireland and Health Service ExecutiveInvited Talk
- O'Halloran AM, Targeting Frailty to Prevent Disability: Insights from The Irish Longitudinal Study on Ageing (TILDA). , National Disability Authority Annual Conference, Dublin, Ireland, 25th September, 2018, National Disability AuthorityInvited Talk
- Daniel Carey, Orna Donoghue, Sarah Gibney, Joanne Feeney, Rose Anne Kenny, Eamon Laird, Christine McGarrigle, Sinead McLoughlin, Triona McNicholas, Irene Mosca, Charles Normand, Aisling O'Halloran, Mary O'Shea, Lorna Roe, Siobhan Scarlett, Katie Tobin, Stephen Thomas, Dominic Trepel, Niall Turner, Mark Ward, Wellbeing And Health In Ireland's Over 50s 2009-2016. , Dublin, Ireland, The Irish Longitudinal Study on Ageing 2018, November, 2018Report, URL
- Tools for Assessing Frailty in Older People: General Concepts. in, editor(s)Nicola Veronese , Frailty and Cardiovascular Diseases, Switzerland, Springer, Cham, 2020, pp9 - 19, [Martin FC, O'Halloran AM.]Book Chapter, DOI , URL
- O'Halloran AM, Frailty in Ireland - A developing landscape, Paul Wagstaff Commemorative Lecture, Dublin, Ireland, 9th September , 2019, Irish Society of Chartered PhysiotherapistsInvited Talk
- Deirdre O'Connor , Anne M. Molloy , Eamon Laird, Rose Anne Kenny and Aisling M. O"Halloran, Sustaining an ageing population: the role of micronutrients in frailty and cognitive impairment, Proceedings of the Nutrition Society, Conference on `Food and nutrition: Pathways to a sustainable future" Symposium four: Sustaining an ageing population, (82), 2023, pp315-328Conference Paper, DOI , TARA - Full Text
- Aisling O'Halloran, Mature Matters: Ageing, 2012, - 1Miscellaneous, URL , TARA - Full Text
- Aisling M. O'Halloran, Falls and Frailty in Ireland - Evidence from the Irish Longitudinal Study on Ageing (TILDA), AGM of Chartered Physiotherapists of Ireland in Neurology and Gerontology, Dublin, Ireland, May 17, 2014, Chartered Physiotherapists of IrelandInvited Talk
Research Expertise
My research interests are focused on the biology of the ageing and age-related disease phenotypes including CVD, frailty and disability. I am also interested in maintaining resilience and intrinsic capacity as we age. My research aims to investigate biomarkers that best capture those who are experiencing accelerated biological ageing and who are therefore at risk for declining health and age-related disease/phenotypes. This information is utilized to inform disease prevention, detection and management strategies, and to improve health and social care policy and service planning. Also, this work will raise public awareness of frailty on the island of Ireland.
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TitleFrailty-related Outcomes and health Care USe (FOCUS)SummaryFunding AgencyHealth Service Executive (HSE)Date FromFebruary 2016Date ToJuly 2017
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TitleFrailty in Ireland North and SouthSummaryThe unprecedented global increase in life expectancy over the past century has lead to a rapidly expanding ageing population, placing ever higher demands on publicly-funded healthcare resources in Ireland, North and South. Current trajectories indicate that such demands are unsustainable. Early identifiers of declining health will be central to measuring health risk. The European Innovation Partnership on Active and Healthy Ageing has highlighted frailty as key to seeking a two year increase in healthy life years by 2020. Resilience and frailty represent opposite ends of a spectrum of decline from robust health to profound functional dependence. Frailty is a driver of functional and cognitive decline, predicting multi-morbidity, disability, increased health care utilisation and mortality (Fried et al, 2001, 2004). However, frailty can be ameliorated by early detection and intervention. Data from The Irish Longitudinal Study of Ageing (TILDA) will be used to track transitions along the frailty spectrum and investigate how frailty-related biomarker profiles of physical, cognitive and psychological health at baseline (Wave 1) change and predict frailty during follow-up (Waves 2 and 3). North-South comparisons between the prevalence and characteristics of frailty using Wave 3 of TILDA and Phase 1 of the Northern Ireland Cohort for Longitudinal Ageing (NICOLA), which coincide during 2014. Will be performed. Elucidating frailty-related risk factors and resource demands in the ageing population will help to identify: (1) new evidence-based targets for pre-clinical frailty detection and intervention, and (2) specific needs that will be vital in delivering efficient, effective healthcare services and increasing healthy life-years into the futureFunding AgencyCARDI - Centre for Ageing Research in IrelandDate FromMarch 2014Date ToFebruary 2017
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TitleThe Irish Longitudinal Ageing Study (TILDA) Nutritional Biomarker Database Enhancement Initiative (BIO-TILDA)SummaryFunding AgencyDept. of Agriculture, Food and Marine (DARM)Date FromJanuary 2014Date ToJanuary 2016
Health services and systems, Public health, Genetics, Cardiovascular medicine and haematology, Medical, health and life sciences, Nutrition and dietetics, Biochemistry and cell biology,
Recognition
- Best Research Presentation. Medical Gerontology Annual Research Meeting, Trinity College, Dublin March 2012
- Department of Agriculture Fisheries and the Marine (DAFM) FIRM/RSF/CoFoRD 2013 Research Award December 2013
- Commendation Award for Scientific Presentation at Irish Gerontological Society Annual (IGS) Scientific Meeting, Dublin September 2011
- Best Abstract Award at Falls Frailty and Bone Health Europe Conference, Dublin. 10/11/2017
- America-Ireland Fund Undergraduate Scholarship Award, Smurfit Institute of Genetics, Trinity College Dublin and School of Medicine, Washington University, St. Louis, Missouri, USA May 1998
- Best Presentation Medal at Irish Gerontological Society Annual Scientific Meeting, Kilarney 01/10/2016
- Platform Presentation Award, Irish Gerontological Society Annual Scientific Meeting, Athlone. 05/10/2024
- CARDI Ageing Research Leadership Award March 2014
- National Institute of Ageing (NIA) Biomarker Network.
- Irish Frailty Network (IFN) - Founding Member present
- Irish Gerontological Society present
- British Geriatrics Society (BGS)
- Executive Committee Member, Irish Gerontological Society 2022
- European Union Geriatric Medicine Society (EUGMS)
- Gerontological Society of America (GSA)
- Irish Society of Immunology