Medicine

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Trinity Biomedical Sciences Institute
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Professor Gerry Hanna

Professor Gerry Hanna

Professor / Consultant Radiation Oncolog, Radiation Therapy

Biography

Professor Gerry Hanna is the Marie Curie Professor of Clinical Oncology at Trinity College Dublin and a Consultant in Radiation Oncology at the St Lukes Radiation Oncology Network and at the Trinity St James Cancer Institute. Gerry also holds honorary appointments at the Peter MacCallum Cancer Centre, Melbourne, the University of Melbourne and Queen"s University Belfast. Prof Hanna completed his undergraduate training at Queen"s University Belfast and his post graduate training at the Cancer Centre, Belfast City Hospital. Following his PhD fellowship, Prof Hanna was awarded the Royal College of Radiologists" Keith Durrant Memorial Travelling Fellowship to undertake a fellowship at the Vrije University Medical Centre in Amsterdam. Prior to taking up his current post, Prof Hanna was Chair of Division for Cancer and Specialist Medicine at Belfast Health and Social Care Trust and prior to this was the Director of Radiation Oncology at the Peter MacCallum Cancer Centre, Melbourne. His Research interests include the use of PET/CT in radiotherapy planning for lung cancer, mechanisms of radiotherapy resistance, stereotactic ablative radiotherapy and systemic therapy and immunotherapy combinations with radiotherapy. He was the chief investigator of the Peter Mac ACRF Radiation Immuno-oncology Program and the International Atomic Energy Agency's PERTAIN study. He is a TMG member for the UK's HALT, SARON, CONFIRM, ISOTOXIC IMRT and CONCORDE studies and continues to provide research support to Belfast Trust.

Publications and Further Research Outputs

  • Sarah Barrett, Gerard G. Hanna, Laure Marignol, An overview on personalisation of radiotherapy prescriptions in locally advanced non-small cell lung cancer: Are we there yet?, Radiotherapy and Oncology, 128, (3), 2018, p520 - 533Review Article, 2018, DOI
  • Haslett, K., Bayman, N., Franks, K., Groom, N., Harden, S.V., Harris, C., Hanna, G., Harrow, S., Hatton, M., McCloskey, P., McDonald, F., Ryder, W.D., Faivre-Finn, C., Isotoxic Intensity Modulated Radiation Therapy in Stage III Non-Small Cell Lung Cancer: A Feasibility Study, International Journal of Radiation Oncology Biology Physics, 109, (5), 2021, p1341-1348Journal Article, 2021, DOI
  • Walls, G.M., Cole, A.J., Hanna, G.G., McAleer, J.J., Local Control: Also a Strength of Radiotherapy Training?, Clinical Oncology, 33, (10), 2021, p676-679Journal Article, 2021, DOI
  • Fennell, D.A., Ewings, S., Ottensmeier, C., Califano, R., Hanna, G.G., Hill, K., Danson, S., Steele, N., Nye, M., Johnson, L., Lord, J., Middleton, C., Szlosarek, P., Chan, S., Gaba, A., Darlison, L., Wells-Jordan, P., Richards, C., Poile, C., Lester, J.F., Griffiths, G., Price, G., Shaw, P., Cave, J., Naik, J., Ford, A., Geldhart, T., Dancey, G., Papadatos, D., Polychronis, A., Jankowska, P., Scott, A., Gardiner, J., Cominos, M., Campbell, L., MacGregor, C., Mullholand, L., Chitnis, M., Dougherty, G., Nivolumab versus placebo in patients with relapsed malignant mesothelioma (CONFIRM): a multicentre, double-blind, randomised, phase 3 trial, The Lancet Oncology, 22, (11), 2021, p1530-1540Journal Article, 2021, DOI
  • Juneja, M., Solomon, B., Hanna, G.G., Nuclear protein in testis carcinoma: a diagnostic and therapeutic challenge, Internal Medicine Journal, 51, (7), 2021, p1191-1192Journal Article, 2021, DOI
  • G.M. Walls and J. O{\textquotesingle, Re: Lewis et al. Palliative Lung Radiotherapy: Higher Dose Leads to Improved Survival?, Clinical Oncology, 2020Journal Article, 2020, DOI
  • Paolo Sogono and Mathias Bressel and Steven David and Mark Shaw and Sarat Chander and Julie Chu and Nikki Plumridge and Keelan Byrne and Nick Hardcastle and Tomas Kron and Greg Wheeler and Gerard G. Hanna and Michael MacManus and David Ball and Shankar Siva, Safety, efficacy and patterns of failure after single fraction stereotactic body radiotherapy (SBRT) for oligometastases, International Journal of Radiation Oncology*Biology*Physics, 2020Journal Article, 2020, DOI
  • C.E. Coles and C. Aristei and J. Bliss and L. Boersma and A.M. Brunt and S. Chatterjee and G. Hanna and R. Jagsi and O. Kaidar Person and A. Kirby and I. Mjaaland and I. Meattini and A.M. Luis and G.N. Marta and B. Offersen and P. Poortmans and S. Rivera, International Guidelines on Radiation Therapy for Breast Cancer During the COVID-19 Pandemic, Clinical Oncology, 32, (5), 2020, p279--281Journal Article, 2020, DOI
  • Gerard Walls and James J McAleer and Gerard G Hanna, Perception of modern radiotherapy learning: study protocol for a mixed-methods analysis of trainees and trainers at a UK cancer centre, BMJ Open, 10, (5), 2020, pe037171Journal Article, 2020, DOI
  • G.M. Walls and G.G. Hanna and R.L. Eakin and L. Young and J. McAleese, Re: Mercieca et al. Implementing the Royal College of Radiologists' Radiotherapy Target Volume Definition and Peer Review Guidelines: More Still to Do?, Clinical Oncology, 32, (5), 2020, p343Journal Article, 2020, DOI
  • C.R. Hanna and D.M. Lynskey and J. Wadsley and S.E. Appleyard and S. Anwar and E. Miles and J. Gower and E. Hall and C.E. Coles and G.G. Hanna, Radiotherapy Trial Set-up in the UK: Identifying Inefficiencies and Potential Solutions, Clinical Oncology, 32, (4), 2020, p266--275Journal Article, 2020, DOI
  • Hwang, E.J., Gorayski, P., Le, H., Hanna, G.G., Kenny, L., Penniment, M., Buck, J., Thwaites, D., Ahern, V., Particle therapy toxicity outcomes: A systematic review, Journal of Medical Imaging and Radiation Oncology, 64, (5), 2020, p725-737Journal Article, 2020, DOI
  • Storey, C.L., Hanna, G.G., Greystoke, A., Practical implications to contemplate when considering radical therapy for stage III non-small-cell lung cancer, British Journal of Cancer, 123, 2020, p28-35Journal Article, 2020, DOI
  • Walls GM, McMahon M, Moore N, Nicol P, Bradley G, Whitten G, Young L, O'Hare JM, Lindsay J, Connolly R, Dermot Linden, Ball PA, Hanna GG, McAleese J, Clinicoradiological outcomes after radical radiotherapy for lung cancer in patients with interstitial lung disease., BJR open, 2023Journal Article, 2023, DOI , TARA - Full Text
  • Wee Loon Ong, Norah Finn, Luc Te Marvelde, Colin Hornby, Roger L Milne, Gerard G Hanna, Graham Pitson, Hany Elsaleh, Jeremy L Millar, Farshad Foroudi, Disparities in radiation therapy utilization for cancer patients in Victoria, Journal of Medical Imaging and Radiation Oncology, 2022Journal Article, 2022, DOI
  • Fiona Hegi-Johnson, Stacey Rudd, Rodney J. Hicks, Dirk De Ruysscher, Joseph A. Trapani, Thomas John, Paul Donnelly, Benjamin Blyth, Gerard Hanna, Sarah Everitt, Peter Roselt, Michael P. MacManus, Imaging immunity in patients with cancer using positron emission tomography, npj Precision Oncology, 2022Journal Article, 2022, DOI
  • Lee, K., Le, T., Hau, E., Hanna, G.G., Gee, H., Vinod, S., Dammak, S., Palma, D., Ong, A., Yeghiaian-Alvandi, R., Buck, J., Lim, R., A Systematic Review Into the Radiologic Features Predicting Local Recurrence After Stereotactic Ablative Body Radiotherapy (SABR) in Patients With Non-Small Cell Lung Cancer (NSCLC), International Journal of Radiation Oncology Biology Physics, 113, (1), 2022, p40-59Journal Article, 2022, DOI
  • Bucknell, N.W., Belderbos, J., Palma, D.A., Iyengar, P., Samson, P., Chua, K., Gomez, D., McDonald, F., Louie, A.V., Faivre-Finn, C., Hanna, G.G., Siva, S., Avoiding Toxicity With Lung Radiation Therapy: An IASLC Perspective, Journal of Thoracic Oncology, 17, (8), 2022, p961-973Journal Article, 2022, DOI
  • Fennell, D.A., Griffiths, G., Ottensmeier, C., Hanna, G.G., Danson, S., Szlosarek, P., Nye, M., CONFIRM trial: what is the real efficacy of second-line immunotherapy in mesothelioma? " Authors' reply, The Lancet Oncology, 23, (1), 2022, pe14-e15Journal Article, 2022, DOI
  • Alomran, R., White, M., Bruce, M., Bressel, M., Roache, S., Karroum, L., Hanna, G.G., Siva, S., Goel, S., David, S., Stereotactic radiotherapy for oligoprogressive ER-positive breast cancer (AVATAR), BMC Cancer, 21, (1), 2021Journal Article, 2021, DOI
  • G. M. Walls and L. McConnell and J. McAleese and P. Murray and T. B. Lynch and K. Savage and G. G. Hanna and D. Gonzalez de Castro, Early circulating tumour DNA kinetics measured by ultra-deep next-generation sequencing during radical radiotherapy for non-small cell lung cancer: a feasibility study, Radiation Oncology, 15, (1), 2020Journal Article, 2020, DOI
  • Gerard M. Walls, Gerard G. Hanna, James J. McAleer, Learning radiotherapy: the state of the art, BMC Medical Education, 20, (1), 2020Journal Article, 2020, DOI
  • Gerard M. Walls and Jamie B. Oughton and Anthony J. Chalmers and Sarah Brown and Fiona Collinson and Martin D. Forster and Kevin N. Franks and Alexandra Gilbert and Gerard G. Hanna and Nicola Hannaway and Stephen Harrow and Tom Haswell and Crispin T. Hiley and Samantha Hinsley and Matthew Krebs and Geraldine Murden and Rachel Phillip and Anderson J. Ryan and Ahmed Salem and David Sebag-Montefoire and Paul Shaw and Chris J. Twelves and Katrina Walker and Robin J. Young and Corinne Faivre-Finn and Alastair Greystoke, CONCORDE: A phase I platform study of novel agents in combination with conventional radiotherapy in non-small-cell lung cancer, Clinical and Translational Radiation Oncology, 25, 2020, p61--66Journal Article, 2020, DOI
  • J. Dhont and S.V. Harden and L.Y.S. Chee and K. Aitken and G.G. Hanna and J. Bertholet, Image-guided Radiotherapy to Manage Respiratory Motion: Lung and Liver, Clinical Oncology, 2020Journal Article, 2020, DOI
  • Hegi-Johnson, F., Rudd, S.E., Wichmann, C., Akhurst, T., Roselt, P., Trinh, J., John, T., Devereux, L., Donnelly, P.S., Hicks, R., Scott, A.M., Steinfort, D., Fox, S., Blyth, B., Parakh, S., Hanna, G.G., Callahan, J., Burbury, K., MacManus, M., ImmunoPET: IMaging of cancer imMUNOtherapy targets with positron Emission Tomography: a phase 0/1 study characterising PD-L1 with 89 Zr-durvalumab (MEDI4736) PET/CT in stage III NSCLC patients receiving chemoradiation study protocol, BMJ Open, 12, (11), 2022Journal Article, 2022, DOI
  • Siva, S., Jones, G., Bressel, M., Shaw, M., Chander, S., Chu, J., Plumridge, N., Byrne, K., Kothari, G., Hardcastle, N., Gaudreault, M., Kron, T., Wheeler, G., MacManus, M., Hanna, G.G., Ball, D.L., David, S., Impact of Medical Operability and Total Metastatic Ablation on Outcomes After SABR for Oligometastases, International Journal of Radiation Oncology Biology Physics, 114, (5), 2022, p862-870Journal Article, 2022, DOI
  • Thippu Jayaprakash, K., Hanna, G.G., Hatton, M.Q., Lung Cancer in 2022 and Beyond!, Clinical Oncology, 34, (11), 2022, p695-697Journal Article, 2022, DOI
  • Walls, G.M., Osman, S.O.S., Brown, K.H., Butterworth, K.T., Hanna, G.G., Hounsell, A.R., McGarry, C.K., Leijenaar, R.T.H., Lambin, P., Cole, A.J., Jain, S., Radiomics for Predicting Lung Cancer Outcomes Following Radiotherapy: A Systematic Review, Clinical Oncology, 34, (3), 2022, pe107-e122Journal Article, 2022, DOI
  • Kothari, G., Woon, B., Patrick, C.J., Korte, J., Wee, L., Hanna, G.G., Kron, T., Hardcastle, N., Siva, S., The impact of inter-observer variation in delineation on robustness of radiomics features in non-small cell lung cancer, Scientific Reports, 12, (1), 2022Journal Article, 2022, DOI
  • S. Newman and N. Bucknell and M. Bressel and P. Tran and B.A. Campbell and S. David and N. Haghighi and G.G. Hanna and D. Kok and M. MacManus and C. Phillips and N. Plumridge and M. Shaw and A. Wirth and G. Wheeler and D. Ball and S. Siva, Long-term Survival with 18-Fluorodeoxyglucose Positron Emission Tomography-directed Therapy in Non-small Cell Lung Cancer with Synchronous Solitary Brain Metastasis, Clinical Oncology, 2020Journal Article, 2020, DOI
  • Gaudreault, M., Yeo, A., Kron, T., Hanna, G.G., Siva, S., Hardcastle, N., Treatment Time Optimization in Single Fraction Stereotactic Ablative Radiation Therapy: A 10-Year Institutional Experience, Advances in Radiation Oncology, 7, (5), 2022Journal Article, 2022, DOI
  • Diez, P., Hanna, G.G., Aitken, K.L., van As, N., Carver, A., Colaco, R.J., Conibear, J., Dunne, E.M., Eaton, D.J., Franks, K.N., Good, J.S., Harrow, S., Hatfield, P., Hawkins, M.A., Jain, S., McDonald, F., Patel, R., Rackley, T., Sanghera, P., Tree, A., Murray, L., UK 2022 Consensus on Normal Tissue Dose-Volume Constraints for Oligometastatic, Primary Lung and Hepatocellular Carcinoma Stereotactic Ablative Radiotherapy, Clinical Oncology, 34, (5), 2022, p288-300Journal Article, 2022, DOI
  • Salem, A., Franks, K., Greystoke, A., Hanna, G.G., Harrow, S., Hatton, M., Hiley, C., McDonald, F., Faivre-Finn, C., Unaccounted Confounders Limit the Ability to Draw Conclusions From Big Data Analysis Comparing Radiotherapy Fractionation Regimens in NSCLC, Journal of Thoracic Oncology, 17, (6), 2022, pe55-e56Journal Article, 2022, DOI
  • Gaudreault, M., Chang, D., Hardcastle, N., Jackson, P., Kron, T., Hanna, G.G., Hofman, M.S., Siva, S., Utility of Biology-Guided Radiotherapy to De Novo Metastases Diagnosed During Staging of High-Risk Biopsy-Proven Prostate Cancer, Frontiers in Oncology, 12, 2022Journal Article, 2022, DOI
  • Walls, G.M., Giacometti, V., Apte, A., Thor, M., McCann, C., Hanna, G.G., O'Connor, J., Deasy, J.O., Hounsell, A.R., Butterworth, K.T., Cole, A.J., Jain, S., McGarry, C.K., Validation of an established deep learning auto-segmentation tool for cardiac substructures in 4D radiotherapy planning scans, Physics and Imaging in Radiation Oncology, 23, 2022, p118-126Journal Article, 2022, DOI
  • Steven David, Gwo Ho, Daphne Day, Marion Harris, Jennifer Tan, Shom Goel, Gerard G. Hanna, Ranjana Srivastava, Gill Kruss, Lachlan McDowell, Michelle White, Enhanced toxicity with CDK 4/6 inhibitors and palliative radiotherapy: Non-consecutive case series and review of the literature, Translational Oncology, 14, (1), 2021, p100939Journal Article, 2021, DOI
  • Walls, G.M., Cole, A.J., McAleer, J.J., Hanna, G.G., A Qualitative Assessment of Radiotherapy Training at a UK Regional Cancer Centre, Clinical Oncology, 33, (4), 2021, p261-269Journal Article, 2021, DOI
  • Akanda, Z.Z., Neeson, P.J., John, T., Barnett, S., Hanna, G.G., Miller, A., Jennens, R., Siva, S., A narrative review of combined stereotactic ablative radiotherapy and immunotherapy in metastatic non-small cell lung cancer, Translational Lung Cancer Research, 10, (6), 2021, p2766-2778Journal Article, 2021, DOI
  • Rulach, R., Ball, D., Chua, K.L.M., Dahele, M., De Ruysscher, D., Franks, K., Gomez, D., Guckenberger, M., Hanna, G.G., Louie, A.V., Moghanaki, D., Palma, D.A., Peedell, C., Salem, A., Siva, S., Videtic, G.M.M., Chalmers, A.J., Harrow, S., An International Expert Survey on the Indications and Practice of Radical Thoracic Reirradiation for Non-Small Cell Lung Cancer, Advances in Radiation Oncology, 6, (2), 2021Journal Article, 2021, DOI
  • Hanna, G.G., John, T., Ball, D.L., Controversies in the role of radiotherapy in pleural mesothelioma, Translational Lung Cancer Research, 10, (4), 2021, p2079-2087Journal Article, 2021, DOI
  • Hanna, G.G., Van Sor"nsen De Koste, J.R., Carson, K.J., O'Sullivan, J.M., Hounsell, A.R., Senan, S., Conventional 3D staging PET/CT in CT simulation for lung cancer: Impact of rigid and deformable target volume alignments for radiotherapy treatment planning, British Journal of Radiology, 84, (1006), 2011, p919-929Journal Article, 2011, DOI
  • Carson, K.J., Hanna, G.G., Hounsell, A.R., Target volume definition with 18F-FDG PET-CT in radiotherapy treatment planning,Wykorzystanie 18F-FDG PET-CT do planowania leczenia napromienianiem, Nowotwory, 61, (4), 2011, p326-331Journal Article, 2011
  • Hanna GG, Carson KJ, Lynch T, McAleese J, Cosgrove VP, Eakin RL, Stewart DP, Zatari A, O'Sullivan JM, Hounsell AR., 18F-fluorodeoxyglucose positron emission tomography/computed tomography-based radiotherapy target volume definition in non-small-cell lung cancer: delineation by radiation oncologists vs. joint outlining with a PET radiologist?, International journal of radiation oncology, biology, physics, 78, (4), 2010, p1040-1051Journal Article, 2010, DOI
  • van Dam IE, van Sörnsen de Koste JR, Hanna GG, Muirhead R, Slotman BJ, Senan S., Improving target delineation on 4-dimensional CT scans in stage I NSCLC using a deformable registration tool., Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 96, (1), 2010, p67-72Journal Article, 2010, DOI
  • Hanna GG, McAleese J, Carson KJ, Stewart DP, Cosgrove VP, Eakin RL, Zatari A, Lynch T, Jarritt PH, Young VA, O'Sullivan JM, Hounsell AR., (18)F-FDG PET-CT simulation for non-small-cell lung cancer: effect in patients already staged by PET-CT., International journal of radiation oncology, biology, physics, 77, (1), 2010, p24-30Journal Article, 2010, DOI
  • Hanna, G.G., Hounsell, A.R., O'Sullivan, J.M., Geometrical Analysis of Radiotherapy Target Volume Delineation: A Systematic Review of Reported Comparison Methods, Clinical Oncology, 22, (7), 2010, p515-525Journal Article, 2010, DOI
  • Hanna GG, McAleese J, Lynch TB, O'Sullivan JM., Standardization of scanning for [18F]fluorodeoxyglucose positron emission tomography., Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 27, (5), 2009, p831-2; author reply 832Journal Article, 2009, DOI
  • Gribben, H., Miller, P., Hanna, G.G., Carson, K.J., Hounsell, A.R., Map-Mrf Segmentation of lung tumours in pet/ct images, Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009, 2009, p290-293Journal Article, 2009, DOI
  • Goody, R.B., Choong, E.S., Calderwood, J., Law, S.J.M., Mazdai, G., Hanna, G.G., McAleer, J.J.A., Mortality within 30 days for patients older than 70 years receiving chemotherapy: A single-institution retrospective analysis, Journal of the Hong Kong College of Radiologists, 12, (3), 2009, p95-102Journal Article, 2009
  • Bucknell, N., Hardcastle, N., Jackson, P., Hofman, M., Callahan, J., Eu, P., Iravani, A., Lawrence, R., Martin, O., Bressel, M., Woon, B., Blyth, B., MacManus, M., Byrne, K., Steinfort, D., Kron, T., Hanna, G., Ball, D., Siva, S., Single-arm prospective interventional study assessing feasibility of using gallium-68 ventilation and perfusion PET/CT to avoid functional lung in patients with stage III non-small cell lung cancer, BMJ Open, 10, (12), 2020Journal Article, 2020, DOI
  • Chan-Kyung Jane Cho and Balamurugan A. Vellayappan and Emma M. Dunne and Shankar Siva and Mitchell Liu and Alexander V. Louie and Gerard G. Hanna and Simon S. Lo, What is synchronous oligometastatic non-small cell lung cancer?, Journal of Thoracic Disease, 11, (12), 2019, p5666--5669Journal Article, 2019, DOI
  • J. McAleese and C.M. Rooney and S. Baluch and K.J. Drinkwater and G.G. Hanna, Curative Radiotherapy for Lung Cancer in the UK: International Benchmarking, Clinical Oncology, 31, (10), 2019, p731Journal Article, 2019, DOI
  • J. McAleese, A. Taylor, G.M. Walls, G.G. Hanna, Differential Relapse Patterns for Non-small Cell Lung Cancer Subtypes Adenocarcinoma and Squamous Cell Carcinoma: Implications for Radiation Oncology, Clinical Oncology, 31, (10), 2019, p711--719Journal Article, 2019, DOI
  • T. Konert and W. V. Vogel and D. Paez and A. Polo and E. Fidarova and H. Carvalho and P. S. Duarte and A. C. Zuliani and A. O. Santos and D. Altuhhova and L. Karusoo and R. Kapoor and A. Sood and J. Khader and A. Al-Ibraheem and Y. Numair and S. Abubaker and C. Soydal and T. Kütük and T. A. Le and N. X. Canh and B. Q. Bieu and L. N. Ha and J. S. A. Belderbos and M. P. MacManus and D. Thorwarth and G. G. Hanna, Introducing FDG PET/CT-guided chemoradiotherapy for stage III NSCLC in low- and middle-income countries: preliminary results from the IAEA PERTAIN trial, European Journal of Nuclear Medicine and Molecular Imaging, 46, (11), 2019, p2235--2243Journal Article, 2019, DOI
  • D. Xing, S. Siva, G.G. Hanna, The Abscopal Effect of Stereotactic Radiotherapy and Immunotherapy: Fool's Gold or El Dorado?, Clinical Oncology, 31, (7), 2019, p432--443Journal Article, 2019, DOI
  • Hanna, G.G., Edgar, D., Clarke, J.E.M., A Case of Prolonged Type 1 Hypersensitivity Reaction to Pegfilgrastim, Clinical Oncology, 20, (4), 2008, p315-316Journal Article, 2008, DOI
  • Hanna, G.G., McDonnell, G.V., A bed bound patient, Postgraduate Medical Journal, 79, (933), 2003Journal Article, 2003
  • Mihaela Ghita and Victoria L. Dunne and Stephen J. McMahon and Sarah O. Osman and Donna M. Small and Sinead Weldon and Clifford C. Taggart and Conor K. McGarry and Alan R. Hounsell and Edward E. Graves and Kevin M. Prise and Gerard G. Hanna and Karl T. Butterworth, Preclinical Evaluation of Dose-Volume Effects and Lung Toxicity Occurring In and Out-of-Field, International Journal of Radiation Oncology*Biology*Physics, 103, (5), 2019, p1231--1240Journal Article, 2019, DOI
  • Mihaela Ghita and Victoria Dunne and Gerard G Hanna and Kevin M Prise and Jaqueline P Williams and Karl T Butterworth, Preclinical models of radiation-induced lung damage: challenges and opportunities for small animal radiotherapy, The British Journal of Radiology, 92, (1095), 2019, p20180473Journal Article, 2019, DOI
  • Walls, G.M., Hanna, G.G., Qi, F., Zhao, S., Xia, J., Ansari, M.T., Landau, D., Corrigendum: Predicting outcomes from radical radiotherapy for non-small cell lung cancer: A systematic review of the existing literature (Frontiers Media S.A. (2018) 8 (433) DOI: 10.3389/fonc.2018.00433), Frontiers in Oncology, 9, (MAR), 2019Journal Article, 2019, DOI
  • Chia, B.S.H., Landau, D., Hanna, G., Conibear, J., Thoracic intervention and surgery to cure lung cancer: an overview of stereotactic ablative radiotherapy in early and oligometastatic lung cancer, Journal of the Royal Society of Medicine, 112, (8), 2019, p334-340Journal Article, 2019, DOI
  • G.G. Hanna, F. McDonald, L. Murray, S. Harrow, D. Landau, M. Ahmed, K.N. Franks, UK Consensus on Normal Tissue Dose Constraints for Stereotactic Radiotherapy: Reply to Ghafoor et al., Clinical Oncology, 30, (7), 2018, p456Journal Article, 2018, DOI
  • G.M. Walls, J. McAleese, G.G. Hanna, Referrals Patterns to an Oncology Clinical Advice Service, Clinical Oncology, 30, (6), 2018, p395--396Journal Article, 2018, DOI
  • G.G. Hanna, L. Murray, R. Patel, S. Jain, K.L. Aitken, K.N. Franks, N. van As, A. Tree, P. Hatfield, S. Harrow, F. McDonald, M. Ahmed, F.H. Saran, G.J. Webster, V. Khoo, D. Landau, D.J. Eaton, M.A. Hawkins, UK Consensus on Normal Tissue Dose Constraints for Stereotactic Radiotherapy, Clinical Oncology, 30, (1), 2018, p5--14Journal Article, 2018, DOI
  • Fennell, D.A., Kirkpatrick, E., Cozens, K., Nye, M., Lester, J., Hanna, G., Steele, N., Szlosarek, P., Danson, S., Lord, J., Ottensmeier, C., Barnes, D., Hill, S., Kalevras, M., Maishman, T., Griffiths, G., CONFIRM: A double-blind, placebo-controlled phase III clinical trial investigating the effect of nivolumab in patients with relapsed mesothelioma: Study protocol for a randomised controlled trial, Trials, 19, (1), 2018Journal Article, 2018, DOI
  • McDonald, F., Hanna, G.G., Oligoprogressive Oncogene-addicted Lung Tumours: Does Stereotactic Body Radiotherapy Have a Role? Introducing the HALT Trial, Clinical Oncology, 30, (1), 2018, p1-4Journal Article, 2018, DOI
  • Walls, G.M., Hanna, G.G., Qi, F., Zhao, S., Xia, J., Ansari, M.T., Landau, D., Predicting outcomes from radical radiotherapy for non-small cell lung cancer: A systematic review of the existing literature, Frontiers in Oncology, 8, (OCT), 2018Journal Article, 2018, DOI
  • Rulach, R., Hanna, G.G., Franks, K., McAleese, J., Harrow, S., Re-irradiation for Locally Recurrent Lung Cancer: Evidence, Risks and Benefits, Clinical Oncology, 30, (2), 2018, p101-109Journal Article, 2018, DOI
  • McAleese, J., Mooney, L., Walls, G.M., Eakin, R.L., Harney, J., Hanna, G.G., Risk of Death from Pneumocystis jirovecii after Curative-intent Radiotherapy for Lung Cancer, Clinical Oncology, 30, (12), 2018, pe81-e82Journal Article, 2018, DOI
  • O'Neill, A., McAleer, S., McCarty, H., Clarke, J., Drake, A., Hurwitz, J., Clayton, A., Shaw, E., Vennard, H., Gray, S., Robinson, J., Simpson, B., Stevenson, M., Hanna, G.G., O'Sullivan, J.M., Semi-permanent tattoos in breast radiotherapy (STaBRad) study: A randomised-controlled clinical trial comparing the 'Precision Plus Micropigmentation System' to permanent skin tattoos in radical breast radiotherapy patients, Journal of Radiotherapy in Practice, 17, (1), 2018, p12-19Journal Article, 2018, DOI
  • Conibear, J., Chia, B., Ngai, Y., Bates, A.T., Counsell, N., Patel, R., Eaton, D., Faivre-Finn, C., Fenwick, J., Forster, M., Hanna, G.G., Harden, S., Mayles, P., Moinuddin, S., Landau, D., Study protocol for the SARON trial: A multicentre, randomised controlled phase III trial comparing the addition of stereotactic ablative radiotherapy and radical radiotherapy with standard chemotherapy alone for oligometastatic non-small cell lung cancer, BMJ Open, 8, (4), 2018Journal Article, 2018, DOI
  • Brown, J.M.C., Hanna, G.G., Lampe, N., Villagomez-Bernabe, B., Nicol, J.R., Coulter, J.A., Currell, F.J., Towards photon radiotherapy treatment planning with high Z nanoparticle radiosensitisation agents: The Relative Biological Effective Dose (RBED) framework, Cancer Nanotechnology, 9, (1), 2018Journal Article, 2018, DOI
  • Murray, P., Franks, K., Hanna, G.G., A systematic review of outcomes following stereotactic ablative radiotherapy in the treatment of early-stage primary lung cancer, British Journal of Radiology, 90, (1071), 2017Journal Article, 2017, DOI
  • Walls, G.M., Lyon, A.R., Harbinson, M.T., Hanna, G.G., Cardiotoxicity following cancer treatment, Ulster Medical Journal, 86, (1), 2017, p3-9Journal Article, 2017
  • McDonald, F., Hanna, G.G., Do protons have a role in the treatment of locally advanced NSCLC with radiotherapy?, Lung Cancer, 110, 2017, p71-73Journal Article, 2017, DOI
  • Walls, G.M., Hanna, G.G., Immunotherapy for lung cancer " A gamechanger!, Ulster Medical Journal, 86, (3), 2017, p213-214Journal Article, 2017
  • Dunne, V., Ghita, M., Small, D.M., Coffey, C.B.M., Weldon, S., Taggart, C.C., Osman, S.O., McGarry, C.K., Prise, K.M., Hanna, G.G., Butterworth, K.T., Inhibition of ataxia telangiectasia related-3 (ATR) improves therapeutic index in preclinical models of non-small cell lung cancer (NSCLC) radiotherapy, Radiotherapy and Oncology, 124, (3), 2017, p475-481Journal Article, 2017, DOI
  • McAleese, J., Baluch, S., Drinkwater, K., Bassett, P., Hanna, G.G., The Elderly are Less Likely to Receive Recommended Radical Radiotherapy for Non-small Cell Lung Cancer, Clinical Oncology, 29, (9), 2017, p593-600Journal Article, 2017, DOI
  • G.G. Hanna, T. Illidge, Radiotherapy and Immunotherapy Combinations in Non-small Cell Lung Cancer: A Promising Future?, Clinical Oncology, 28, (11), 2016, p726--731Journal Article, 2016, DOI
  • McLaughlin, K.A., Nemeth, Z., Bradley, C.A., Humphreys, L., Stasik, I., Fenning, C., Majkut, J., Higgins, C., Crawford, N., Holohan, C., Johnston, P.G., Harrison, T., Hanna, G.G., Butterworth, K.T., Prise, K.M., Longley, D.B., FLIP: A targetable mediator of resistance to radiation in non-small cell lung cancer, Molecular Cancer Therapeutics, 15, (10), 2016, p2432-2441Journal Article, 2016, DOI
  • Konert, T., Vogel, W.V., Everitt, S., MacManus, M.P., Thorwarth, D., Fidarova, E., Paez, D., Sonke, J.-J., Hanna, G.G., Multiple training interventions significantly improve reproducibility of PET/CT-based lung cancer radiotherapy target volume delineation using an IAEA study protocol, Radiotherapy and Oncology, 121, (1), 2016, p39-45Journal Article, 2016, DOI
  • Harrow, S., Hanna, G.G., Faivre-Finn, C., McDonald, F., Chalmers, A.J., The Challenges Faced in Developing Novel Drug Radiation Combinations in Non-small Cell Lung Cancer, Clinical Oncology, 28, (11), 2016, p720-725Journal Article, 2016, DOI
  • Anna Kirby, Gerard Hanna, Maggie Wilcox, Mairead MacKenzie, In Regard to Vaidya et al, International Journal of Radiation Oncology*Biology*Physics, 92, (5), 2015, p957--958Journal Article, 2015, DOI
  • Hanna GG, Kirby AM., Intraoperative radiotherapy in early stage breast cancer: potential indications and evidence to date., The British journal of radiology, 88, (1049), 2015, p20140686Journal Article, 2015, DOI
  • Hanna GG, Landau D., Stereotactic body radiotherapy for oligometastatic disease., Clinical oncology (Royal College of Radiologists (Great Britain)), 27, (5), 2015, p290-297Journal Article, 2015, DOI
  • Hanna GG, Coyle VM, Prise KM., Immune modulation in advanced radiotherapies: Targeting out-of-field effects., Cancer letters, 368, (2), 2015, p246-251Journal Article, 2015, DOI
  • Konert T, Vogel W, MacManus MP, Nestle U, Belderbos J, Grégoire V, Thorwarth D, Fidarova E, Paez D, Chiti A, Hanna GG., PET/CT imaging for target volume delineation in curative intent radiotherapy of non-small cell lung cancer: IAEA consensus report 2014., Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 116, (1), 2015, p27-34Journal Article, 2015, DOI
  • O'Connell, B.F., Irvine, D.M., Cole, A.J., Hanna, G.G., McGarry, C.K., Optimizing geometric accuracy of four-dimensional CT scans acquired using the wall- and couch-mounted Varian® real-time position management" camera systems, British Journal of Radiology, 88, (1046), 2015Journal Article, 2015, DOI
  • Hanna, G.G., Landau, D., Re: Stereotactic Body Radiotherapy for Oligometastatic Disease, Clinical Oncology, 27, (9), 2015, p543-544Journal Article, 2015, DOI
  • Cole, A., Hanna, G.G., Stereotactic radiotherapy for early stage lung cancer, Ulster Medical Journal, 84, (1), 2015, p69-70Journal Article, 2015
  • Rooney, K.P., McAleese, J., Crockett, C., Harney, J., Eakin, R.L., Young, V.A.L., Dunn, M.A., Johnston, R.E., Hanna, G.G., The Impact of Colleague Peer Review on the Radiotherapy Treatment Planning Process in the Radical Treatment of Lung Cancer, Clinical Oncology, 27, (9), 2015, p514-518Journal Article, 2015, DOI
  • Cole, A.J., O'Hare, J.M., McMahon, S.J., McGarry, C.K., Butterworth, K.T., McAleese, J., Jain, S., Hounsell, A.R., Prise, K.M., Hanna, G.G., O'Sullivan, J.M., Investigating the potential impact of four-dimensional computed tomography (4DCT) on toxicity, outcomes and dose escalation for radical lung cancer radiotherapy, Clinical Oncology, 26, (3), 2014, p142-150Journal Article, 2014, DOI
  • Cole, A.J., Hanna, G.G., Jain, S., O'Sullivan, J.M., Motion management for radical radiotherapy in non-small cell lung cancer, Clinical Oncology, 26, (2), 2014, p67-80Journal Article, 2014, DOI
  • Hanna, G.G., Siva, S., Plumridge, N., Solomon, B., Ball, D.L., Preoperative chemotherapy for nonsmall-cell lung cancer, The Lancet, 384, (9939), 2014, p232-233Journal Article, 2014, DOI
  • Khan K, Hanna GG, Campbell L, Scullin P, Hussain A, Eakin RL, McAleese J., Re-challenge chemotherapy with gemcitabine plus carboplatin in patients with non-small cell lung cancer., Chinese journal of cancer, 32, (10), 2013, p539-545Journal Article, 2013, DOI
  • Booth K, Hanna GG, McGonigle N, McManus KG, McGuigan J, O'Sullivan J, Lynch T, McAleese J., The mediastinal staging accuracy of 18F-Fluorodeoxyglycose positron emission tomography/computed tomography in non-small cell lung cancer with variable time intervals to surgery., The Ulster medical journal, 82, (2), 2013, p75-81Journal Article, 2013, DOI
  • Hanna G., So you want to be an oncologist?, The Ulster medical journal, 82, (1), 2013, p65Journal Article, 2013, DOI
  • Hanna, G., So you want to be an: Oncologist?, Ulster Medical Journal, 82, (1), 2013, p65Journal Article, 2013
  • Booth, K., Hanna, G.G., McGonigle, N., McManus, K.G., McGuigan, J., O'Sullivan, J., Lynch, T., McAleese, J., The mediastinal staging accuracy of 18F-Fluorodeoxyglycose positron emission tomography / computed tomography in non-small cell lung cancer with variable time intervals to surgery, Ulster Medical Journal, 82, (2), 2013, p75-81Journal Article, 2013
  • Goody, R.B., O'Hare, J., McKenna, K., Earey, L.D., Robinson, J., Bell, P., Clarke, J., McAleer, J.J.A., O'Sullivan, J.M., Hanna, G.G., Unintended cardiac irradiation during left-sided breast cancer radiotherapy, British Journal of Radiology, 86, (1022), 2013Journal Article, 2013, DOI
  • Hanna, G.G., Van Sörnsen de Koste, J.R., Dahele, M.R., Carson, K.J., Haasbeek, C.J.A., Migchielsen, R., Hounsell, A.R., Senan, S., Defining Target Volumes for Stereotactic Ablative Radiotherapy of Early-stage Lung Tumours: A Comparison of Three-dimensional 18F-fluorodeoxyglucose Positron Emission Tomography and Four-dimensional Computed Tomography, Clinical Oncology, 24, (6), 2012Journal Article, 2012, DOI

Research Expertise

- Use of PET/CT in radiotherapy planning for lung cancer - Mechanisms of radiotherapy resistance - Stereotactic ablative radiotherapy (SABR/SBRT) - Systemic therapy and immunotherapy combinations with radiotherapy. - Chief investigator of International Atomic Energy Agency"s "PERTAIN" study. - Former chief investigator of the Peter Mac ACRF Radiation Immuno-oncology Program - Former chief investigator of the UK's CONCORDE Study. - TMG member for the UK"s HALT, SARON, CONFIRM, ISOTOXIC IMRT and CONCORDE studies

Solid tumours, Cancer, Radiation therapy, Cancer not elsewhere classified,

Recognition

  • Winner of the NI Healthcare Oncology Team Award April 2024
  • Robert Campbell Oration Medal - Ulster Medical Society October 2011
  • Winner of Pearl Ewing Travelling Fellowship, Friends of the Cancer Centre, Belfast, N. Ireland. 2009
  • Winner of Royal College of Radiologists, Keith Durrant Memorial Travelling Fellowship May 2009
  • Winner of the St. Luke's Medal September 2007
  • UK National Quality in Care Oncology Award 2016
  • Winner of Best Post-Graduate Research, Faculty of Medicine, Annual Celebration of Excellence, Queen's University Belfast 2011
  • Member of the British Medical Association
  • Supporting Ambassador of the European Society for Therapeutic Radiology and Oncology (ESTRO)
  • Fellow Ulster Medical Society
  • Honorary Fellow of the Faculty of Radiation Oncology and Radiology, Royal College of Surgeons of Ireland
  • Member of British Thoracic Oncology Group (BTOG)
  • Member of International Society for the Study of Lung Cancer (IASLC)
  • Member of the Royal College of Physicians of London
  • Vice-Clinical Lead of Cancer Trials Ireland
  • Fellow of the Royal College of Radiologists, London
  • Fellow of the Royal Australian and New Zealand College of Radiologists July 2024
  • Founding Board Member of the Thoracic Oncology Group of Australasia. Jully 2021
  • Member of American Society for Therapeutic Radiology and Oncology (ASTRO)