Lab Publications

2024:

Bloomfield, M., Lautarescu, A., Heraty, S., Douglas, S., Violland, P., Plas, R., Ghosh, A., Van Den Bosch, K., Eaton, E., Absoud, M., Battini, R., Blázquez Hinojosa, A., Bolshakova, N., Bölte, S., Bonanni, P., Borg, J., Calderoni, S., Calvo Escalona, R., Castelo-Branco, M., … Charman, T. (2024). European Autism GEnomics Registry (EAGER): Protocol for a multicentre cohort study and registry. BMJ Open, 14(6), e080746. https://doi.org/10.1136/bmjopen-2023-080746

Breetvelt, E., Safarian, N., Engchuan, W., Trost, B., Mendes De Aquino, M., Gallagher, L., Scherer, S. W., & Vorstman, J. (2024). 86. Low Frequency Genetic Variants Orchestrate Genetic Vulnerability for Autism Spectrum Disorders and Schizophrenia in Concert With Rare and Common Variants. Biological Psychiatry, 95(10), S134. https://doi.org/10.1016/j.biopsych.2024.02.321

Hickie, I. B., LaMonica, H. M., Guastella, A. J., Boulton, K. A., Ospina-Pinillos, L., Szatmari, P., Gallagher, L., & Crouse, J. J. (2024). What childhood and related developmental factors are relevant to the risk of onset and course of depression and other mood disorders? Research Directions: Depression, 1, e5. https://doi.org/10.1017/dep.2023.19

Kurth, F., Schijven, D., Van Den Heuvel, O. A., Hoogman, M., Van Rooij, D., Stein, D. J., Buitelaar, J. K., Bölte, S., Auzias, G., Kushki, A., Venkatasubramanian, G., Rubia, K., Bollmann, S., Isaksson, J., Jaspers‐Fayer, F., Marsh, R., Batistuzzo, M. C., Arnold, P. D., Bressan, R. A., … Luders, E. (2024a). Large‐scale analysis of structural brain asymmetries during neurodevelopment: Associations with age and sex in 4265 children and adolescents. Human Brain Mapping, 45(11), e26754. https://doi.org/10.1002/hbm.26754

Kurth, F., Schijven, D., Van Den Heuvel, O. A., Hoogman, M., Van Rooij, D., Stein, D. J., Buitelaar, J. K., Bölte, S., Auzias, G., Kushki, A., Venkatasubramanian, G., Rubia, K., Bollmann, S., Isaksson, J., Jaspers‐Fayer, F., Marsh, R., Batistuzzo, M. C., Arnold, P. D., Bressan, R. A., … Luders, E. (2024b). Large‐scale analysis of structural brain asymmetries during neurodevelopment: Associations with age and sex in 4265 children and adolescents. Human Brain Mapping, 45(11), e26754. https://doi.org/10.1002/hbm.26754

Ní Ghrálaigh, F., Brennan, A., Bolshakova, N., Foley, M., Gallagher, L., & Lopez, L. M. (2022).

Establishing an Irish autism research network. Irish Journal of Psychological Medicine, 41(1),

157–158. https://doi.org/10.1017/ipm.2022.39

Summers, J., Baribeau, D., Perlman, P., Hoang, N., Cui, S., Krakowski, A., Ambrozewicz, P., Ho, A., Selvanayagam, T., Sándor-Bajusz, K. A., Palad, K., Patel, N., McGaughey, S., Gallagher, L., Scherer, S. W., Szatmari, P., & Vorstman, J. (2024). An integrated clinical approach to children at genetic risk for neurodevelopmental and psychiatric conditions: Interdisciplinary collaboration and research infrastructure. Journal of Neurodevelopmental Disorders, 16(1), 37. https://doi.org/10.1186/s11689-024-09552-x

2023:

Bölte, S., Neufeld, J., Marschik, P. B., Williams, Z. J., Gallagher, L., & Lai, M.-C. (2023). Sex

and gender in neurodevelopmental conditions. Nature Reviews Neurology, 19(3), 136–159.

https://doi.org/10.1038/s41582-023-00774-6

Conlan, K., McGrath, J., Teeling, M., MacAvin, M. J., Bennett, K., & Gallagher, L. (2023).

Antipsychotic prescribing in GMS paediatric and young adult population in Ireland 2005–2015:

Repeated cross-sectional study. Irish Journal of Psychological Medicine, 40(3), 343–352.

https://doi.org/10.1017/ipm.2021.7

Dinneen, T., Molloy, C. J., Cliquet, F., Leblond, C. S., Bourgeron, T., Cooke, J., Loth, E.,

Buitelaar, J. K., Lopez, L. M., & Gallagher, L. (2023). F59. DISSECTING THE

CONTRIBUTIONS OF RARE AND COMMON GENETIC VARIATION TO

NEURODEVELOPMENTAL OUTCOMES. European Neuropsychopharmacology, 75, S253.

https://doi.org/10.1016/j.euroneuro.2023.08.446

Heraty, S., Lautarescu, A., Belton, D., Boyle, A., Cirrincione, P., Doherty, M., Douglas, S., Plas,

1. R. D., Van Den Bosch, K., Violland, P., Tercon, J., Ruigrok, A., Murphy, D. G. M.,

Bourgeron, T., Chatham, C., Loth, E., Oakley, B., McAlonan, G. M., Charman, T., … Jones, E.

1. H. (2023). Bridge-building between communities: Imagining the future of biomedical autism

research. Cell, 186(18), 3747–3752. https://doi.org/10.1016/j.cell.2023.08.004

Molloy, C. J., Cooke, J., Gatford, N. J. F., Rivera-Olvera, A., Avazzadeh, S., Homberg, J. R.,

Grandjean, J., Fernandes, C., Shen, S., Loth, E., Srivastava, D. P., & Gallagher, L. (2023).

Bridging the translational gap: What can synaptopathies tell us about autism? Frontiers in

Molecular Neuroscience, 16, 1191323. https://doi.org/10.3389/fnmol.2023.1191323

Molloy, C. J., Quigley, C., McNicholas, Á., Lisanti, L., & Gallagher, L. (2023). A review of the

cognitive impact of neurodevelopmental and neuropsychiatric associated copy number variants.

Translational Psychiatry, 13(1), 116. https://doi.org/10.1038/s41398-023-02421-6

Ní Ghrálaigh, F., McCarthy, E., Murphy, D. N., Gallagher, L., & Lopez, L. M. (2023). Brief

Report: Evaluating the Diagnostic Yield of Commercial Gene Panels in Autism. Journal of

Autism and Developmental Disorders, 53(1), 484–488.

https://doi.org/10.1007/s10803-021-05417-7

Vibert, B., Segura, P., Gallagher, L., Georgiades, S., Pervanidou, P., Thurm, A., Alexander, L.,

Anagnostou, E., Aoki, Y., Birken, C. S., Bishop, S. L., Boi, J., Bravaccio, C., Brentani, H.,

Canevini, P., Carta, A., Charach, A., Costantino, A., Cost, K. T., … Di Martino, A. (2023).

CRISIS AFAR: An international collaborative study of the impact of the COVID-19 pandemic

on mental health and service access in youth with autism and neurodevelopmental conditions.

Molecular Autism, 14(1), 7. https://doi.org/10.1186/s13229-022-00536-z

2022:

Carter, M., Casey, S., O’Keeffe, G. W., Gibson, L., Gallagher, L., & Murray, D. M. (2022).

Maternal Immune Activation and Interleukin 17A in the Pathogenesis of Autistic Spectrum

Disorder and Why It Matters in the COVID-19 Era. Frontiers in Psychiatry, 13, 823096.

https://doi.org/10.3389/fpsyt.2022.823096

Cooke, J., Molloy, C. J., Cáceres, A. S. J., Dinneen, T., Bourgeron, T., Murphy, D., Gallagher,

L., & Loth, E. (2022). The Synaptic Gene Study: Design and Methodology to Identify

Neurocognitive Markers in Phelan-McDermid Syndrome and NRXN1 Deletions. Frontiers in

Neuroscience, 16, 806990. https://doi.org/10.3389/fnins.2022.806990

Dinneen, T. J., Ghrálaigh, F. N., Walsh, R., Lopez, L. M., & Gallagher, L. (2022). How does

genetic variation modify ND-CNV phenotypes? Trends in Genetics, 38(2), 140–151.

https://doi.org/10.1016/j.tig.2021.07.006

Fitzgerald, J., & Gallagher, L. (2022). Parental stress and adjustment in the context of rare

genetic syndromes: A scoping review. Journal of Intellectual Disabilities, 26(2), 522–544.

https://doi.org/10.1177/1744629521995378

Gallagher, L., & McGrath, J. (2022). Autism spectrum disorders: Current issues and future

directions. Irish Journal of Psychological Medicine, 39(3), 237–239.

https://doi.org/10.1017/ipm.2022.34

Hoogman, M., Van Rooij, D., Klein, M., Boedhoe, P., Ilioska, I., Li, T., Patel, Y., Postema, M.

C., Zhang‐James, Y., Anagnostou, E., Arango, C., Auzias, G., Banaschewski, T., Bau, C. H. D.,

Behrmann, M., Bellgrove, M. A., Brandeis, D., Brem, S., Busatto, G. F., … Franke, B. (2022).

Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum

disorder: The ENIGMA adventure. Human Brain Mapping, 43(1), 37–55.

https://doi.org/10.1002/hbm.25029

Molloy, C. J. (2022). 27.2 Translational Biomarkers in Rare Genetic Synaptopathies Associated With ASD. Journal of the American Academy of Child & Adolescent Psychiatry, 61(10), S318. https://doi.org/10.1016/j.jaac.2022.07.710

Molloy, C. J., & Gallagher, L. (2022). Can stratification biomarkers address the heterogeneity of

autism spectrum disorder? Irish Journal of Psychological Medicine, 39(3), 305–311.

https://doi.org/10.1017/ipm.2021.73

Patel, Y., Shin, J., Abé, C., Agartz, I., Alloza, C., Alnæs, D., Ambrogi, S., Antonucci, L. A.,

Arango, C., Arolt, V., Auzias, G., Ayesa-Arriola, R., Banaj, N., Banaschewski, T., Bandeira, C.,

Başgöze, Z., Cupertino, R. B., Bau, C. H. D., Bauer, J., … Paus, T. (2022). Virtual Ontogeny of

Cortical Growth Preceding Mental Illness. Biological Psychiatry, 92(4), 299–313.

https://doi.org/10.1016/j.biopsych.2022.02.959

Sha, Z., Van Rooij, D., Anagnostou, E., Arango, C., Auzias, G., Behrmann, M., Bernhardt, B.,

Bolte, S., Busatto, G. F., Calderoni, S., Calvo, R., Daly, E., Deruelle, C., Duan, M., Duran, F. L.

S., Durston, S., Ecker, C., Ehrlich, S., Fair, D., … Francks, C. (2022). Subtly altered topological

asymmetry of brain structural covariance networks in autism spectrum disorder across 43

datasets from the ENIGMA consortium. Molecular Psychiatry, 27(4), 2114–2125.

https://doi.org/10.1038/s41380-022-01452-7

Trost, B., Thiruvahindrapuram, B., Chan, A. J. S., Engchuan, W., Higginbotham, E. J., Howe, J.

L., Loureiro, L. O., Reuter, M. S., Roshandel, D., Whitney, J., Zarrei, M., Bookman, M.,

Somerville, C., Shaath, R., Abdi, M., Aliyev, E., Patel, R. V., Nalpathamkalam, T., Pellecchia,

G., … Scherer, S. W. (2022). Genomic architecture of autism from comprehensive

whole-genome sequence annotation. Cell, 185(23), 4409-4427.e18.

https://doi.org/10.1016/j.cell.2022.10.009

2021:

Abstracts From the 23rd Annual Meeting of the Irish Society of Human Genetics: Virtual Conference, 25th September 2020. (2021). Irish Journal of Medical Science (1971 -), 190(S2), 61–76. https://doi.org/10.1007/s11845-021-02517-2

Avazzadeh, S., Quinlan, L. R., Reilly, J., McDonagh, K., Jalali, A., Wang, Y., McInerney, V.,

Krawczyk, J., Ding, Y., Fitzgerald, J., O’Sullivan, M., Forman, E. B., Lynch, S. A., Ennis, S.,

Feerick, N., Reilly, R., Li, W., Shen, X., Yang, G., … Gallagher, L. (2021). NRXN1α+/- is

associated with increased excitability in ASD iPSC-derived neurons. BMC Neuroscience, 22(1),

56. https://doi.org/10.1186/s12868-021-00661-0

Chawner, S. J. R. A., Doherty, J. L., Anney, R. J. L., Antshel, K. M., Bearden, C. E., Bernier, R.,

Chung, W. K., Clements, C. C., Curran, S. R., Cuturilo, G., Fiksinski, A. M., Gallagher, L.,

Goin-Kochel, R. P., Gur, R. E., Hanson, E., Jacquemont, S., Kates, W. R., Kushan, L., Maillard,

1. M., … Van Den Bree, M. B. M. (2021). A Genetics-First Approach to Dissecting the

Heterogeneity of Autism: Phenotypic Comparison of Autism Risk Copy Number Variants. American Journal of Psychiatry, 178(1), 77–86. https://doi.org/10.1176/appi.ajp.2020.20010015

Conlan, K., Gallagher, L., Hogan, A., & McGrath, J. (2021). P.109 Antipsychotics cause the

development of an inflammatory phenotype: A 12-month longitudinal study. European

Neuropsychopharmacology, 44, S7–S8. https://doi.org/10.1016/j.euroneuro.2021.01.016

Ding, Y., O’Brien, A., De La Cruz, B. M., Yang, M., Fitzgerald, J., Yang, G., Li, W.,

McInerney, V., Krawczyk, J., Lynch, S. A., Howard, L., Allen, N. M., O’Brien, T., Gallagher,

L., & Shen, S. (2021). Derivation of iPSC lines from two patients with autism spectrum disorder

carrying NRXN1α deletion (NUIGi041-A, NUIG041-B; NUIGi045-A) and one sibling control

(NUIGi042-A, NUIGi042-B). Stem Cell Research, 52, 102222.

https://doi.org/10.1016/j.scr.2021.102222

Ding, Y., O’Brien, A., Marcó De La Cruz, B., Yang, M., Lu, Y., Qian, X., Yang, G., McInerney,

V., Krawczyk, J., Lynch, S. A., Howard, L., Allen, N. M., O’Brien, T., Gallagher, L., & Shen, S.

(2021). Derivation of four iPSC lines from a male ASD patient carrying a deletion in the middle

coding region of NRXN1α gene (NUIGi039-A and NUIGi039-B) and a male sibling control

(NUIGi040-A and NUIGi040-B). Stem Cell Research, 53, 102254.

https://doi.org/10.1016/j.scr.2021.102254

Fitzgerald, J., Wilson, C., Kelly, C., & Gallagher, L. (2021). ‘More than a box of puzzles’:

Understanding the parental experience of having a child with a rare genetic condition". European

Journal of Medical Genetics, 64(4), 104164. https://doi.org/10.1016/j.ejmg.2021.104164

Ghrálaigh, F. N., Dinneen, T. J., McCarthy, E., Murphy, D. N., Gallagher, L., & Lopez, L.

(2021). W15. DETERMINING THE CLINICAL UTILITY OF GENE PANELS IN AUTISM: A

STUDY OF DIAGNOSTIC YIELD, RELEVANCE, AND PENETRANCE. European

Neuropsychopharmacology, 51, e155. https://doi.org/10.1016/j.euroneuro.2021.08.107

Mezinska, S., Gallagher, L., Verbrugge, M., & Bunnik, E. M. (2021). Ethical issues in genomics

research on neurodevelopmental disorders: A critical interpretive review. Human Genomics,

15(1), 16. https://doi.org/10.1186/s40246-021-00317-4

Oakley, B., Tillmann, J., Ruigrok, A., Baranger, A., Takow, C., Charman, T., Jones, E., Cusack,

J., Doherty, M., Violland, P., Wroczyńska, A., Simonoff, E., Buitelaar, J. K., Gallagher, L., &

Murphy, D. G. M. (2021). COVID-19 health and social care access for autistic people: European

policy review. BMJ Open, 11(6), e045341. https://doi.org/10.1136/bmjopen-2020-045341

Schwartz, L., Caixàs, A., Dimitropoulos, A., Dykens, E., Duis, J., Einfeld, S., Gallagher, L.,

Holland, A., Rice, L., Roof, E., Salehi, P., Strong, T., Taylor, B., & Woodcock, K. (2021).

Behavioral features in Prader-Willi syndrome (PWS): Consensus paper from the International

PWS Clinical Trial Consortium. Journal of Neurodevelopmental Disorders, 13(1), 25.

https://doi.org/10.1186/s11689-021-09373-2

2020:

Cosemans, N., Vandenhove, L., Vogels, A., Devriendt, K., Van Esch, H., Van Buggenhout, G.,

Olivié, H., De Ravel, T., Ortibus, E., Legius, E., Aerssens, P., Breckpot, J., R. Vermeesch, J.,

Shen, S., Fitzgerald, J., Gallagher, L., & Peeters, H. (2020). The clinical relevance of intragenic

NRXN1 deletions. Journal of Medical Genetics, 57(5), 347–355.

https://doi.org/10.1136/jmedgenet-2019-106448

Feighan, S. ‐M., Hughes, M., Maunder, K., Roche, E., & Gallagher, L. (2020). A profile of

mental health and behaviour in Prader–Willi syndrome. Journal of Intellectual Disability

Research, 64(2), 158–169. https://doi.org/10.1111/jir.12707

Lin, B. D., Colas, F., Nijman, I. J., Medic, J., Brands, W., Parr, J. R., Van Eijk, K. R., Klauck, S.

M., Chiocchetti, A. G., Freitag, C. M., Maestrini, E., Bacchelli, E., Coon, H., Vicente, A.,

Oliveira, G., Pagnamenta, A. T., Gallagher, L., Ennis, S., Anney, R., … Vorstman, J. (2020). The

role of rare compound heterozygous events in autism spectrum disorder. Translational

Psychiatry, 10(1), 204. https://doi.org/10.1038/s41398-020-00866-7

Ní Ghrálaigh, F., Gallagher, L., & Lopez, L. M. (2020). Autism spectrum disorder genomics:

The progress and potential of genomic technologies. Genomics, 112(6), 5136–5142.

https://doi.org/10.1016/j.ygeno.2020.09.022

Reilly, J., Gallagher, L., Leader, G., & Shen, S. (2020). Coupling of autism genes to tissue-wide

expression and dysfunction of synapse, calcium signalling and transcriptional regulation. PLOS

ONE, 15(12), e0242773. https://doi.org/10.1371/journal.pone.0242773

Journal Articles