The Department of Immunology in Trinity’s School of Medicine, located in St. James's Hospital, provides a clinical and diagnostic service to St. James’s and Tallaght Hospitals, carries out laboratory research in immunology, and provides teaching at undergraduate and postgraduate levels. The clinical areas of expertise include autoimmune disease, primary immunodeficiencies, allergy, vasculitis and connective tissue disorders.  Ongoing research includes basic studies on the biology of human leukocytes and their roles and treatment potential in infectious disease (including HIV, SARS-CoV-2, fungal infections and sepsis caused by bacterial infection), cancer (including ovarian, oesophageal and blood cancers), allogeneic stem cell transplantation and CAR-T cell therapy, antibody deficiencies and neonatal encephalopathy.  The immunology department has also identified novel immunodeficiencies and autoinflammatory disorders and is developing new tests for the diagnosis of these diseases.