Professor John O'Leary
Professor Consultant, Histopathology
Professor Consultant
Email olearyjj@tcd.ie Phone3531896 3296http://people.tcd.ie/olearyjjProfessor John O’Leary holds the positions of Professor/Chair of Pathology, Trinity College Dublin, Director of Pathology, The Coombe Women and Infants University Hospital, Dublin, and Consultant Histopathologist, St. James’ Hospital, Dublin, Ireland. His consultant diagnostic experience includes Gynaecological pathology, Breast pathology, Gastrointestinal pathology, Molecular diagnostic pathology and Cytopathology. Prof. John O’Leary heads a multi-investigator group of 40 scientists at TCD focused on the molecular characterisation of several cancer systems including: Ovary, cervix, prostate, thyroid and head and neck cancer and cancer stem cell biology and the diagnosis of paediatric infections. In addition, the laboratory has a significant international reputation in the area of pregnancy proteomics and transcriptomics. His laboratory is a European reference centre for Applied Biosystems and Affymetrix and holds significant grant income from national and international sources including EU6th FP, EU7th FP, HRB, Irish Cancer Society and several foundations including the Emer Casey Foundation (dedicated to ovarian and uterine research). The individual groups are focussed on using functional genomics to understand the causes and molecular basis of the development of disease, with particular reference to cancer and cancer related systems. Projects include CERVIVA (The Irish Cervical Screening Research Consortium – ICSRC) – A consortium of researchers dedicated to performing high quality research with a view to better understanding cervical cancer and how it develops and delivering the best possible information and guidance to support cervical screening services for women and DISCOVARY- A consortium of international researchers which was formed to specifically address issues in relation to ovarian and endometrial cancer diagnostics and prognostics and supports the development of translational research in Ireland. DISCOVARY has now merged with INNOVATION- the Irish National Network for Ovarian Cancer Collaboration. Prof O’Leary has a h-index of 49 and in excess of 9,600 citations. He has published in excess of 190 peer reviewed papers and in excess of 400 publications and is seated editor on three books. He recently received a Life Achievement award for Cancer Research at the RNAi 2011 International conference at Oxford University.
Dept. of Histopathology
Trinity College Dublin
College Green
Dublin 2
Ireland
Publications and Further Research Outputs
- Loy A, McInerney J, Pilkington L, Keegan H, Delamere S, Martin CM, Sheils O, O'Leary JJ, Mulcahy F., Human papillomavirus DNA and mRNA prevalence and association with cervical cytological abnormalities in the Irish HIV population., International Journal of Sexually Transmitted Diseases and AIDS, 2014Journal Article, 2014
- Bonnier,F, Traynor, D, Kearney, P, Clarke,C, Peter Knief, P Martin, C, O'Leary,J, Byrne HJ and Lyng, F, Processing ThinPrep Cervical Cytological Samples for Raman Spectroscopic Analysis., Analytical Methods, 6, (19), 2014, p7831 - 7841Journal Article, 2014
- d'Adhemar CJ, Spillane CD, Gallagher MF, Bates M, Costello KM, Barry-O'Crowley J, Haley K, Kernan N, Murphy C, Smyth PC, O'Byrne K, Pennington S, Cooke AA, Ffrench B, Martin CM, O'Donnell D, Hennessy B, Stordal B, Finn S, McCann A, Gleeson N, D'Arcy T, Flood B, O'Neill LA, Sheils O, O'Toole S, O'Leary JJ, The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer., PloS one, 9, (6), 2014, pe100816Journal Article, 2014, DOI , TARA - Full Text
- Vencken SF, Sethupathy P, Blackshields G, Spillane C, Elbaruni S, Sheils O, Gallagher MF, O'Leary JJ, An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines., BMC genomics, 15, 2014, p711Journal Article, 2014, DOI , TARA - Full Text
- Rashid N, Nawaz H, Poon KW, Bonnier F, Bakhiet S, Martin C, O'Leary JJ, Byrne HJ, Lyng FM, Raman microspectroscopy for the early detection of pre-malignant changes in cervical tissue., Experimental and molecular pathology, 97, (3), 2014, p554-64Journal Article, 2014
- O'Connor M, Costello L, Murphy J, Prendiville W, Martin CM, O'Leary JJ, Sharp L, Influences on human papillomavirus (HPV)-related information needs among women having HPV tests for follow-up of abnormal cervical cytology., The journal of family planning and reproductive health care / Faculty of Family Planning & Reproductive Health Care, Royal College of Obstetricians & Gynaecologists, 41, (2), 2015, p134-141Journal Article, 2015, DOI
- Keegan H, Pilkington L, McInerney J, Jeney C, Benczik M, Cleary S, von Bunau G, Turner M, D'Arcy T, O' Toole S, Pal-Szenthe B, Kaltenecker B, Mózes J, Kovács A, Solt A, Bolger N, O'Leary J, Martin C, Human papillomavirus detection and genotyping, by HC2, full-spectrum HPV and molecular beacon real-time HPV assay in an Irish colposcopy clinic., Journal of virological methods, 201, 2014, p93-100Journal Article, 2014
- Langhe R, Norris L, Saadeh FA, Blackshields G, Varley R, Harrison A, Gleeson N, Spillane C, Martin C, O'Donnell DM, D'Arcy T, O'Leary J, O'Toole S, A novel serum microRNA panel to discriminate benign from malignant ovarian disease., Cancer letters, 356, (2 Pt B), 2015, p628-36Journal Article, 2015, DOI
- McRae, J. Martin, C. O'Leary, J. Sharp, L., "If you can't treat HPV, why test for it?" Women's attitudes to the changing face of cervical cancer prevention: A focus group study, BMC Women's Health, 14, (1), 2014, p64-Journal Article, 2014, DOI , URL , TARA - Full Text
- Lawlor, D. Martin, P. Busschots, S. Thery, J. O'Leary, J.J. Hennessy, B.T. Stordal, B., PARP inhibitors as p-glyoprotein substrates, Journal of Pharmaceutical Sciences, 103, (6), 2014, p1913 - 1920Journal Article, 2014, DOI , URL
- O'Connor, M. Murphy, J. Martin, C. O'Leary, J. Sharp, L., Motivators for women to attend cervical screening: The influential role of GPs, Family Practice, 31, (4), 2014, p475-482Journal Article, 2014, DOI , URL , TARA - Full Text
- Ffrench B, Gasch C, O'Leary JJ, Gallagher MF, Developing ovarian cancer stem cell models: laying the pipeline from discovery to clinical intervention., Molecular cancer, 13, 2014, p262Journal Article, 2014, DOI , TARA - Full Text
- McEvoy, L.M., O'Toole, S.A., Spillane, C.D., Martin, C.M., Gallagher, M.F., Stordal, B., Blackshields, G., Sheils, O., O'Leary, J.J., Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer, BMC Cancer, 15, (1), 2015, p547-Journal Article, 2015, DOI , TARA - Full Text
- Gallagher, M.F., Salley, Y., Spillane, C.D., Ffrench, B., Baruni, S.E., Blacksheilds, G., Smyth, P., Martin, C., Sheils, O., Watson, W., O'Leary, J.J., Enhanced regulation of cell cycle and suppression of osteoblast differentiation molecular signatures by prostate cancer stem-like holoclones, Journal of Clinical Pathology, 68, (9), 2015, p692-702Journal Article, 2015, DOI
- Cooke, N.M., Spillane, C.D., Sheils, O., O'Leary, J., Kenny, D., Aspirin and P2Y
12 inhibition attenuate platelet-induced ovarian cancer cell invasion, BMC Cancer, 15, (1), 2015, p627-Journal Article, 2015, DOI , TARA - Full Text - Staunton, L., Tonry, C., Lis, R., Finn, S., O'Leary, J., Loda, M., Bowden, M., Pennington, S.R., Profiling the tumor microenvironment proteome in prostate cancer using laser capture microdissection coupled to LC-MS-A technical report, EuPA Open Proteomics, 10, 2016, p19-23Journal Article, 2016
- Emma R Dorris, Gordon Blackshields, Gary Sommerville, Mohsen Alhashemi, Andrew Dias, Victoria McEneaney, Paul Smyth, John J O'Leary, Orla Sheils, Pluripotency markers are differentially induced by MEK inhibition in thyroid and melanoma BRAFV600E cell lines, Cancer biology & therapy, 17, (5), 2016, p526 - 542Journal Article, 2016, DOI
- Johnson IR, Parkinson-Lawrence EJ, Keegan H, Spillane CD, Barry-O'Crowley J, Watson WR, Selemidis S, Butler LM, O'Leary JJ, Brooks DA, Endosomal gene expression: a new indicator for prostate cancer patient prognosis?, Oncotarget, 6, (35), 2015, p37919-29Journal Article, 2015, DOI , TARA - Full Text
- Aherne, S.T., Smyth, P., Freeley, M., Smith, L., Spillane, C., O'Leary, J., Sheils, O., Altered expression of MIR-222 and MIR-25 influences diverse gene expression changes in transformed normal and anaplastic thyroid cells, and impacts on MEK and TRAIL protein expression, International Journal of Molecular Medicine, 38, (2), 2016, p433-445Journal Article, 2016, DOI
- O'Connor M, O'Leary E, Waller J, Gallagher P, D'Arcy T, Flannelly G, Martin C.M, McRae J, Prendiville W, Ruttle C, White C, Pilkington L, O'Leary J.J, Sharp L, Trends in, and predictors of, anxiety and specific worries following colposcopy: A 12-month longitudinal study, Psycho-Oncology, 25, (5), 2016, p597 - 604Journal Article, 2016, DOI , URL
- Holl K, Nowakowski A.M, Powell N, McCluggage W.G, Pirog E.C, Collas De Souza S, Tjalma W.A, Rosenlund M, Fiander A, Castro Sánchez M, Damaskou V, Joura E.A, Kirschner B, Koiss R, O'Leary J, Quint W, Reich O, Torné A, Wells M, Rob L, Kolomiets L, Molijn A, Savicheva A, Shipitsyna E, Rosillon D, Jenkins D, Human papillomavirus prevalence and type-distribution in cervical glandular neoplasias: Results from a European multinational epidemiological study, International Journal of Cancer, 137, (12), 2015, p2858 - 2868Journal Article, 2015, DOI , URL
- O'Connor M, Waller J, Gallagher P, Martin C.M, O'Leary J.J, D'Arcy , Prendiville W, Flannelly G, Sharp L, Understanding Women's Differing Experiences of Distress after Colposcopy: A Qualitative Interview Study, Women's Health Issues, 25, (5), 2015, p528 - 534Journal Article, 2015, DOI , URL
- O'Connor M, Costello L, Murphy J, Prendiville W, Martin C.M, O'Leary J.J, Sharp L, 'I don't care whether it's HPV or ABC, i just want to know if i have cancer.' Factors influencing women's emotional responses to undergoing human papillomavirus testing in routine management in cervical screening: A qualitative study, BJOG: An International Journal of Obstetrics and Gynaecology, 121, (11), 2014, p1421 - 1429Journal Article, 2014, DOI , URL
- Glynn M, Kirby D, Nwankire C, Kinahan D, Spillane C, Shiels O, O'Leary J, Ducrée J, Staging the clinical status from blood of cancer patients by chip-based cell enumeration following targetted removal of normal cells, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, 2014, 2014, pp461 - 463Conference Paper, 2014, URL
- Sheill, Gráinne and Brady, Lauren and Guinan, Emer and Hayes, Brian and Casey, Orla and Greene, John and Vlajnic, Tatjana and Cahill, Fidelma and Van Hemelrijck, Mieke and Peat, Nicola and Rudman, Sarah and Hussey, Juliette and Cunningham, Moya and Grogan, Liam and Lynch, Thomas and Manecksha, Rustom P and McCaffrey, John and Mucci, Lorelei and Sheils, Orla and O'Leary, John and O'Donnell, Dearbhaile M and McDermott, Ray and Finn, Stephen, The ExPeCT (Examining Exercise, Prostate Cancer and Circulating Tumour Cells) trial: study protocol for a randomised controlled trial, Trials, 18, (1), 2017, p456Journal Article, 2017, DOI , URL
- Staunton Lisa, Tonry Claire, Lis Rosina, Espina Virginia, Liotta Lance, Inzitari Rosanna, Bowden Michaela, Fabre Aurelie, O'Leary John, Finn Stephen P, Loda Massimo, Pennington Stephen R, Pathology-Driven Comprehensive Proteomic Profiling of the Prostate Cancer Tumor Microenvironment , Molecular cancer research : MCR , 15 , (3 ), 2017, p281 - 293Journal Article, 2017, DOI , URL
- Kearney P, Traynor D, Bonnier F, Lyng FM, O'Leary JJ, Martin CM., Raman spectral signatures of cervical exfoliated cells from liquid-based cytology samples., Journal of biomedical optics, 22, (10), 2017, p1-10Journal Article, 2017, DOI
- Traynor D, Kearney P, Ramos I, Martin CM, O'Leary JJ, Lyng FM., A study of hormonal effects in cervical smear samples using Raman spectroscopy., Journal of biophotonics, 2018, pe201700240-Journal Article, 2018, DOI
- Woods RSR, Keegan H, White C, Tewari P, Toner M, Kennedy S, O'Regan EM, Martin CM, Timon CVI, O'Leary JJ., Cytokeratin 7 in Oropharyngeal Squamous Cell Carcinoma: A Junctional Biomarker for Human Papillomavirus-Related Tumors., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 26, (5), 2017, p702-710Journal Article, 2017, DOI
- O'Connor M, O'Brien K, Waller J, Gallagher P, D'Arcy T, Flannelly G, Martin CM, McRae J, Prendiville W, Ruttle C, White C, Pilkington L, O'Leary JJ, Sharp L, Irish Cervical Screening Research Consortium (CERVIVA)., Physical after-effects of colposcopy and related procedures, and their inter-relationship with psychological distress: a longitudinal survey., BJOG : an international journal of obstetrics and gynaecology, 124, (9), 2017, p1402-1410Journal Article, 2017, DOI
- O'Connor M, Gallagher P, Waller J, Martin CM, O'Leary JJ, Sharp L, Irish Cervical Screening Research Consortium (CERVIVA)., Adverse psychological outcomes following colposcopy and related procedures: a systematic review., BJOG : an international journal of obstetrics and gynaecology, 123, (1), 2016, p24-38Journal Article, 2016, DOI
- Gasch, C. and Ffrench, B. and O'Leary, J.J. and Gallagher, M.F., Catching moving targets: Cancer stem cell hierarchies, therapy-resistance & considerations for clinical intervention, Molecular Cancer, 16, (1), 2017, p43-Journal Article, 2017, DOI , URL , TARA - Full Text
- A. J. Wakefield, A. Anthony, S. H. Murch, M. Thomson, S. M. Montgomery, S. Davies, J. J. O'Leary, M. Berelowitz and J. A. Walker-Smith, Enterocolitis in children with developmental disorders, The American Journal of Gastroenterology, 95, (9), 2000, p2285-2295Journal Article, 2000, DOI
- A. M. Cotter, C. M. Martin, J. O'Leary J and S. F. Daly, Increased fetal DNA in the maternal circulation in early pregnancy is associated with an increased risk of preeclampsia, American Journal of Obstetrics and Gynecology, 191, (2), 2004, p515-520Journal Article, 2004, DOI
- Turner, M.J., Martin C.M., O'Leary, J.J. , Detection of fetal Rhesus D gene in whole blood of women booking for routine antenatal care, European journal of obstetrics, gynecology, and reproductive biology, 108, (1), 2003, p29-32Journal Article, 2003, DOI
- B. M. Byrne, A. Crowley, F. Taulo, J. Anthony, J. J. O'Leary and C. O'Herlihy, Fetal DNA quantitation in peripheral blood is not useful as a marker of disease severity in women with preeclampsia, Hypertension in pregnancy, 22, (2), 2003, p157-64Journal Article, 2003, DOI
- O. Sheils, P. Smyth, S. Finn, E. C. Sweeney and J. J. O'Leary, RET/PTC rearrangements in Hashimoto's thyroiditis, International Journal of Surgical Pathology, 10, (2), 2002, p167-8; author reply 168-9Journal Article, 2002, DOI
- Smyth, P., Sheils, O., Finn, S., Martin, C., O 'Leary, J., Sweeney, E.C, Real time Quantitative Analysis of E-cadherin expression in ret/PTC-1-Activated Thyroid Neoplasms., International Journal of Surgical Pathology , 9, (4), 2001, p265-272Journal Article, 2001, URL
- S. P. Finn, P. Smyth, J. O'Leary, E. C. Sweeney and O. Sheils, Ret/PTC chimeric transcripts in an Irish cohort of sporadic papillary thyroid carcinoma, Journal of Clinical Endocrinology and Metabolism, 88, (2), 2003, p938-941Journal Article, 2003, DOI
- Murphy N, Ring M, Killalea AG, Uhlmann V, O'Donovan M, Mulcahy F, Turner M, Mc Guinness E, Griffin M, Martin, C, Sheils O, O'Leary JJ., p16INK4A as a marker for cervical dyskaryosis: CIN and cGIN in cervical biopsies and ThinPrep smears, Journal of Clinical Pathology, 56, (1), 2003, p56-63Journal Article, 2003, DOI
- J. J. O'Leary, R. J. Landers, M. Crowley, I. Healy, W. F. Kealy, J. Hogan, C. Cullinane, P. Kelehan and C. T. Doyle, Genotypic mapping of HPV and assessment of EBV prevalence in endocervical lesions, Journal of Clinical Pathology, 50, (11), 1997, p904-910Journal Article, 1997, DOI
- M. Ring, N. Bolger, M. O'Donnell, A. Malkin, N. Bermingham, E. Akpan, F. Mulcahy, M. J. Turner, M. Griffin and J. J. O'Leary, Evaluation of liquid-based cytology in cervical screening of high-risk populations: a split study of colposcopy and genito-urinary medicine populations, Cytopathology, 13, (3), 2002, p152-9Journal Article, 2002, DOI
- P. Smyth, S. Finn, J. O'Leary and O. Sheils, Real-time analysis of beta- and gamma-catenin mRNA expression in ret/PTC-1 activated and nonactivated thyroid tissues, Diagnostic Molecular Pathology, 12, (1), 2003, p44-49Journal Article, 2003, DOI
- J. Skinner, K. Luettich, M. Ring, J. J. O'Leary and M. J. Turner, Analysis of fetal DNA in the maternal venous blood for abnormalities of chromosomes 13, 16, 18 and 21 in first-trimester spontaneous miscarriage, Journal of obstetrics and gynaecology, 23, (3), 2003, p228-232Journal Article, 2003, DOI
- O. M. Sheils, J. J. O'Leary and E. C. Sweeney, Assessment of ret/PTC-1 rearrangements in neoplastic thyroid tissue using TaqMan RT-PCR, The Journal of Pathology, 192, (1), 2000, p32-36Journal Article, 2000, DOI
- J. J. O'Leary, V. Uhlmann and A. J. Wakefield, Measles virus and autism, Lancet, 356, (9231), 2000, p772Journal Article, 2000, DOI
- Uhlmann*, V., Martin*, C.M., Sheils, O., Pilkington, L., Silva, I., Killalea, A., Murch, S.B.,Walker-Smith, J., Thomson, M., Wakefield, A.J., O'Leary, J.J. , Potential viral pathogenic mechanism for new variant inflammatory bowel disease, Molecular pathology, 55, (2), 2002, p84-90Journal Article, 2002, DOI
- M. O'Donovan, I. Silva, V. Uhlmann, N. Bermingham, K. Luttich, C. Martin, O. Sheils, A. Killalea, C. Kenny, S. Pileri and J. J. O'Leary, Expression profile of human herpesvirus 8 (HHV-8) in pyothorax associated lymphoma and in effusion lymphoma, Molecular pathology, 54, (2), 2001, p80-85Journal Article, 2001, DOI
- M. O'Donovan, J. M. Russell, J. J. O'Leary, J. A. Gillan, M. P. Lawler and E. F. Gaffney, Abl expression, tumour grade, and apoptosis in chondrosarcoma, Molecular Pathology, 52, (6), 1999, p341-4Journal Article, 1999, DOI
- O'Leary J, Kennedy M, Howells D, Silva I, Uhlmann V, Luttich K, Biddolph S, Lucas S, Russell J, Bermingham N, O'Donovan M, Ring M, Kenny C, Sweeney M, Sheils O, Martin C, Picton S, Gatter K, Cellular localisation of HHV-8 in Castleman's disease: is there a link with lymph node vascularity?, Journal of Clinical Pathology - Molecular Pathology, 53, (2), 2000, p69-76Journal Article, 2000, DOI
- Uhlmann, V., Prasad, M., Silva, I., Luettich, K., Grande, L., Alonso, L., Thisted, M., Pluzek, K.J., Gorst, J., Ring, M., Sweeney, M., Kenny, C., Martin, C., Russell, J., Bermingham, N., O'Donovan, M., Sheils, O., O'Leary, J.J, Improved in situ detection method for telomeric tandem repeats in metaphase spreads and interphase nuclei, Molecular pathology, 53, (1), 2000, p48-50Journal Article, 2000, DOI
- O'Leary, J.J., Kennedy, M., Luttich, K., Uhlmann, V., Silva, I., Russell, J., Sheils, O., Ring, M., Sweeney, M., Kenny, C., Bermingham, N., Martin, C., O'Donovan, M., Howells, D., Picton, S., Lucas, S.B, Localisation of HHV-8 in AIDS related lymphadenopathy, Molecular Pathology, 53, (1), 2000, p43-47Journal Article, 2000, DOI
- Martin CM, Uhlmann V, Killalea A, Sheils O, O'Leary JJ. , Detection of measles virus in children with ileo-colonic lymphoid nodular hyperplasia, enterocolitis and developmental disorder, Molecular psychiatry, 7 Suppl 2, 2002, pS47-s48Journal Article, 2002, DOI
- C. Boshoff, T. F. Schulz, M. M. Kennedy, A. K. Graham, C. Fisher, A. Thomas, J. O. McGee, R. A. Weiss and J. J. O'Leary, Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cells, Nature Medicine, 1, (12), 1995, p1274-1278Journal Article, 1995, DOI
- O. Flore, S. Rafii, S. Ely, J. J. O'Leary, E. M. Hyjek and E. Cesarman, Transformation of primary human endothelial cells by Kaposi's sarcoma-associated herpesvirus, Nature, 394, (6693), 1998, p588-92Journal Article, 1998, DOI
- J. Skinner, K. Luettich, M. Ring, J. J. O'Leary and M. J. Turner, Fetal DNA in maternal circulation of first-trimester spontaneous abortions, Obstetrics and gynecology, 97, (3), 2001, p460-463Journal Article, 2001, DOI , URL
- N. Murphy, C. C. Heffron, B. King, U. G. Ganuguapati, M. Ring, E. McGuinness, O. Sheils and J. J. O'Leary, P16(INK4A) positivity in benign, premalignant and malignant cervical glandular lesions: a potential diagnostic problem, Virchows Archiv, 445, (6), 2004, p610-615Journal Article, 2004, DOI
- S. P. Finn, P. Smyth, E. O'Regan, S. Cahill, R. Flavin, J. O'Leary and O. Sheils, Array comparative genomic hybridisation analysis of gamma-irradiated human thyrocytes, Virchows Arch, 445, (4), 2004, p396-404Journal Article, 2004, DOI
- Tewari P, Kashdan E, Walsh C, Martin CM, Parnell AC, O'Leary JJ., Estimating the conditional probability of developing human papilloma virus related oropharyngeal cancer by combining machine learning and inverse Bayesian modelling., PLoS computational biology, 17, (8), 2021, pe1009289Journal Article, 2021, DOI
- O'Donovan B, Mooney T, Rimmer B, Fitzpatrick P, Flannelly G, Doherty L, Martin C, O'Leary J, O'Connor M, Sharp L., Advancing understanding of influences on cervical screening (non)-participation among younger and older women: A qualitative study using the theoretical domains framework and the COM-B model., Health expectations : an international journal of public participation in health care and health policy, 2021Journal Article, 2021, DOI
- Spillane CD, Cooke NM, Ward MP, Kenny D, Blackshields G, Kelly T, Bates M, Huang Y, Martin C, Skehan S, Canney A, Gallagher M, Smyth P, Brady N, Clarke A, Mohamed B, Norris L, Brooks DA, Brooks RD, Heatlie JK, Selemidis S, Hanniffy S, Dixon E, Sheils O, O'Toole SA, O'Leary JJ., The induction of a mesenchymal phenotype by platelet cloaking of cancer cells is a universal phenomenon., Translational oncology, 14, (12), 2021, p101229Journal Article, 2021, DOI
- Martini C, Logan JM, Sorvina A, Gordon C, Beck AR, S-Y Ung B, Caruso MC, Moore C, Hocking A, Johnson IRD, Li KL, Karageorgos L, Hopkins AM, Esterman AJ, Huzzell C, Brooks RD, Lazniewska J, Hickey SM, Bader C, Parkinson-Lawrence E, Weigert R, Sorich MJ, Tewari P, Martin C, O'Toole S, Bates M, Ward M, Mohammed B, Keegan H, Watson W, Prendergast S, Heffernan S, NiMhaolcatha S, O'Connor R, Malone V, Carter M, Ryan K, Brady N, Clarke A, Sokol F, Prabhakaran S, Stahl J, Klebe S, Samaratunga H, Delahunt B, Selemidis S, Moretti KL, Butler LM, O'Leary JJ, Brooks DA., Aberrant protein expression of Appl1, Sortilin and Syndecan-1 during the biological progression of prostate cancer., Pathology, 2022, pS0031-3025(22)00226-4Journal Article, 2022, DOI
- Lazniewska J., Bader C., Hickey S.M., Selemidis S., O'Leary J., Simpson P.V., Stagni S., Plush S.E., Massi M., Brooks D., Rhenium ( I ) conjugates as tools for tracking cholesterol in cells, Metallomics, 14, (8), 2022Journal Article, 2022, DOI
- O'Donovan B., Mooney T., Rimmer B., Fitzpatrick P., Flannelly G., Doherty L., Russell N., Martin C.M., O'Leary J.J., Sharp L., O'Connor M., Corrigendum to "Trust and cancer screening: Effects of a screening controversy on women's perceptions of cervical cancer screening" [Prev. Med. Rep. 25 (2022) 101684] (Preventive Medicine Reports (2022) 25, (S2211335521003752), (10.1016/j.pmedr.2021.101684)), Preventive Medicine Reports, 27, 2022Journal Article, 2022, DOI
- O'Donovan B., Mooney T., Rimmer B., Fitzpatrick P., Flannelly G., Doherty L., Russell N., Martin C.M., O'Leary J.J., Sharp L., O'Connor M., Trust and cancer screening: Effects of a screening controversy on women's perceptions of cervical cancer screening, Preventive Medicine Reports, 25, 2022Journal Article, 2022, DOI
- DNA Sequencing in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp531 - 539, [Martin, C.M., Picton, S.J. Sheils, O., O'Leary, J.J.]Book Chapter, 2005
- High density SNP and cDNA array analysis in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp515 - 521, [Sheils, O., Smyth, P., Sherlock, J., Martin, C.M., Finn, S., O'Regan, E.M., O'Leary, J.J.]Book Chapter, 2005
- Real Time PCR gene analysis in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp495 - 504, [Martin, C.M., Sheils, O, O'Leary, J.J.]Book Chapter, 2005
- CGH array analysis of human tissues in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp523 - 528, [O'Regan, E, Martin, C.M., Finn, S, Smyth, P., Flavin, R., O'Leary, J.J. Sheils, O.]Book Chapter, 2005
- In-cell PCR in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp505 - 513, [O'Leary, J.J., Martin, C.M., Sheils, O.]Book Chapter, 2005
- Laser capture microdissection in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp489 - 493, [Sheils, O., Smyth, P., O'Regan, E.M.,Finn, S., Flavin, R., O'Leary, J.J.]Book Chapter, 2005
- Molecular markers in cervical dyskaryosis in, editor(s)Davies P.O.,Prendiville W , The Clinican's HPV handbook (vol 1), Parthenon Medical Publishing, 2005, pp73 - 88, [Murphy, N., Ring, M., Sheils, O., O'Leary, J.J.]Book Chapter, 2005
- Murphy AJ, Hughes CA, Barrett C, Magee H, Loftus B, O'Leary JJ, Sheils O, Low Level TOP2A Amplification in Prostate Cancer is associated with HER2 Duplication, Androgen Resistance and Decreased Survival, Cancer Research , 67, (6), 2007, p2893 - 2898Journal Article, 2007, DOI
- Finn SP, Smyth P, Cahill S, Streck C, O'regan EM, Flavin R, Sherlock J,Howells D, Henfrey R, Cullen M, Toner M, Timon C, O'leary JJ, Sheils OM, Expression microarray analysis of papillary thyroid carcinoma and benign thyroid tissue: emphasis on the follicular variant and potential markers of malignancy, Virchows Arch, 450, (3), 2007, p249 - 260Journal Article, 2007, DOI
- Murphy AJ, Hughes CA, Lannigan G, Sheils O, O'Leary J, Loftus B, Heterogeneous expression of alpha-methylacyl-CoA racemase in prostatic cancer correlates with Gleason score, Histopathology, 50, (2), 2007, p243 - 251Journal Article, 2007, DOI
- Crowley A, Martin C, Fitzpatrick P, Sheils O, O'Herlihy C, O'Leary JJ, Byrne BM, Free fetal DNA is not increased before 20 weeks in intrauterine growth, Prenat Diagn., 27, (2), 2007, p174 - 179Journal Article, 2007, DOI
- Leahy M, Farah N, Bolger N, O'Leary JJ, Turner MJ, Should cervical smears be taken at a postnatal visit?, Irish Medical Journal, 99, (8), 2006, p244 - 245Journal Article, 2006
- O'Toole SA, Sheppard BL, Laios A, O'Leary JJ, McGuinness EP, D'Arcy T,Bonnar J, Potential predictors of chemotherapy response in ovarian cancer--how do we define chemosensitivity?, Gynecol Oncol., 104, (2), 2007, p345 - 351Journal Article, 2007, DOI
- Bolger N, Heffron C, Regan I, Sweeney M, Kinsella S, McKeown M, Creighton G,Russell J, O'Leary J, Implementation and evaluation of a new automated interactive image analysis system, Acta Cytol., 50, (5), 2006, p483 - 491Journal Article, 2006
- Logan C, O'Leary JJ, O'Sullivan N, Real-time reverse transcription-PCR for detection of rotavirus and adenovirus as causative agents of acute viral gastroenteritis in children, J Clin Microbiol., 44, (9), 2006, p3189 - 3195Journal Article, 2006, DOI
- O'Toole SA, Dunn E, Sheppard BL, Klocker H, Bektic J, Smyth P, Martin C, Sheils O, O'Leary JJ, Genome-wide analysis of deoxyribonucleic acid in endometrial cancer using comparative genomic hybridization microarrays, International Journal of Gynecological Cancer , 16, (2), 2006, p834 - 842Journal Article, 2006, DOI
- Hughes C, Murphy A, Martin C, Fox E, Ring M, Sheils O, Loftus B, O'Leary J, Topoisomerase II-alpha expression increases with increasing Gleason score and with hormone insensitivity in prostate carcinoma, Journal of Clinical Pathology, 59, (7), 2006, p721 - 724Journal Article, 2006, DOI
- Martin CM, Astbury K, O'Leary JJ, Molecular profiling of cervical neoplasia, Expert Review of Molecular Diagnostics , 6, (2), 2006, p217 - 229Journal Article, 2006, DOI
- O'Regan EM, Timon C, Sheils O, Codd M, O'Leary JJ, Toner M, Squamous cell carcinoma of the head and neck in young Irish adults, British Journal of Oral and Maxillofacial Surgery , 44, (3), 2006, p203 - 206Journal Article, 2006, DOI
- Hughes C, Murphy A, Martin C, Sheils O, O'Leary J, Molecular pathology of prostate cancer, Journal of Clinical Pathology, 58, (7), 2005, p673 - 684Journal Article, 2005, DOI
- O'Toole SA, Sheppard BL, Sheils O, O'Leary JJ, Spengler B, Christoffel V, Analysis of DNA in endometrial cancer cells treated with phyto-estrogenic compounds using comparative genomic hybridisation microarrays, Planta Medica, 71, (5), 2005, p435 - 439Journal Article, 2005, DOI
- O'Toole SA, Dunn E, Sheppard BL, Sheils O, O'Leary JJ, Wuttke W,, Oestrogen regulated gene expression in normal and malignant endometrial tissue, Maturitas, 51, (2), 2005, p187 - 198Journal Article, 2005, DOI
- Murphy N, Ring M, Heffron CC, King B, Killalea AG, Hughes C, Martin CM,McGuinness E, Sheils O, O'Leary JJ, p16INK4A, CDC6, and MCM5: predictive biomarkers in cervical preinvasive, Journal of Clinical Pathology, 58, (5), 2005, p525 - 534Journal Article, 2005, DOI
- Mocanu EV, Adala S, O'Leary JJ, Womb with a view, Human Fertility (Camb)., 8, (1), 2005, p35 - 40Journal Article, 2005, DOI
- Smyth P, Finn S, Cahill S, O'Regan E, Flavin R, O'Leary JJ, Sheils O, ret/PTC and BRAF act as distinct molecular, time-dependant triggers in a sporadic Irish cohort of papillary thyroid carcinoma, International Journal of Surgical Pathology, 13, (1), 2005, p1 - 8Journal Article, 2005, DOI
- Pathology 2026: The future of laboratory medicine and academic pathology in, editor(s)John Wiley & Sons , Understanding disease, John Wiley & Sons, 2006, pp217 - 231, [O'Leary JJ]Book Chapter, 2006
- Tumour markers in cervical cancer in, editor(s)Jordan JA, Singer A , The Cervix, Blackwell Publishing, 2006, pp399 - 413, [O'Leary JJ, Astbury K, Prendiville W]Book Chapter, 2006
- Keegan, H., Mc Inerney, J., Pilkington, L., Grønn, P., Silva, I., Karlsen, F., Bolger, N., (...), Martin, C. , Comparison of HPV detection technologies: Hybrid capture 2, PreTect HPV-Proofer and analysis of HPV DNA viral load in HPV16, HPV18 and HPV33 E6/E7 mRNA positive specimens, Journal of Virological Methods , 155, (1), 2009, p61-66Journal Article, 2009, DOI
- Aherne ST, Smyth PC, Flavin RJ, Russell SM, Denning KM, Li JH, Guenther SM, O'Leary JJ, Sheils OM., Geographical mapping of a multifocal thyroid tumour using genetic alteration analysis & miRNA profiling., Molecular Cancer, 7, 2008, particle no, 89Journal Article, 2008, DOI
- Hornig, M., Briese, T., Buie, T., Bauman, M.L., Lauwers, G., Siemetzki, U., Hummel, K., (...), Lipkin, W.I. , Lack of association between measles virus vaccine and autism with enteropathy: A case-control study , PLoS ONE, 3, (9), 2008, part. no. e3140Journal Article, 2008, DOI
- Laios, A., O'Toole, S., Flavin, R., Martin, C., Kelly, L., Ring, M., Finn, S.P., (...), O'Leary, J. , Potential role of miR-9 and miR-223 in recurrent ovarian cancer , Molecular Cancer, 7, 2008, part. no. 35Journal Article, 2008, DOI , TARA - Full Text
- Laios, A., O'Toole, S.A., Flavin, R., Martin, C., Ring, M., Gleeson, N., D'Arcy, T., (...), O' Leary, J.J. , An integrative model for recurrence in ovarian cancer , Molecular Cancer, 7, 2008Journal Article, 2008, DOI
- Logan, C., O'Leary, J.J., O'Sullivan, N. , Real-time reverse transcription PCR detection of norovirus, sapovirus and astrovirus as causative agents of acute viral gastroenteritis , Journal of Virological Methods, 146, (1-2), 2007, p36-44Journal Article, 2007, DOI
- Furuberg, L., Mielnik, M., Johansen, I.-R., Voitel, J., Gulliksen, A., Solli, L., Karlsen, F., (...), Koltay, P. , The micro active project: Automatic detection of disease-related molecular cell activity , Proceedings of SPIE - The International Society for Optical Engineering, 6589, 2007, part. no. 65891BJournal Article, 2007, DOI
- Martin CM, Kehoe L, Spillane CO, O'Leary JJ., Gene discovery in cervical cancer : towards diagnostic and therapeutic biomarkers., Molecular Diagnosis and Therapy , 11, (5), 2007, p277-90Journal Article, 2007
- Heffron, C.C.B.B., Gallagher, M.F., Guenther, S., Sherlock, J., Henfrey, R., Martin, C., Sheils, O., O'Leary, J.J. , Global mRNA analysis to determine a transcriptome profile of cancer stemness in a mouse model , Anticancer Research, 27, (3A), 2007, p1319-1324Journal Article, 2007, URL
- Bolger, N., Heffron, C., Regan, I., Sweeney, M., Kinsella, S., McKeown, M., Creighton, G., (...), O'Leary, J. , Cervical cytology: Implementation and evaluation of a new automated interactive image analysis system , Acta Cytologica, 50 - (5), 2006, p483-491Journal Article, 2006
- Astbury, K., Martin, C.M., Ring, M., Pilkington, L., Bolger, N., Sheils, O.M., O'Leary, J.J. , Future molecular aspects of cervical cytology , Current Diagnostic Pathology, 12, (2), 2006, p104-113Journal Article, 2006, DOI
- Murphy, N., Ring, M., Heffron, C.C.B.B., Martin, C.M., McGuinness, E., Sheils, O., O'Leary, J.J., Quantitation of CDC6 and MCM5 mRNA in cervical intraepithelial neoplasia and invasive squamous cell carcinoma of the cervix, Modern Pathology , 18, (6), 2005, p844-849Journal Article, 2005, DOI
- Bofin, A.M., Ytterhus, B., Martin, C., O'Leary, J.J., Hagmar, B.M., Detection and quantitation of HER-2 gene amplification and protein expression in breast carcinoma , American Journal of Clinical Pathology, 122, (1), 2004, p110-119Journal Article, 2004, DOI
- Turner, M.J., Martin, C.M., O'Leary, J.J., Letter to the Editor [2] , 2003, - 118Miscellaneous, 2003, DOI
- O'Leary, J.J., Potential viral pathogenic mechanism for new variant inflammatory bowel disease [1] , 2003, - 248Miscellaneous, 2003, DOI
- Sheils, O., Finn, S., O'Leary, J., Nucleic acid microarrays: An overview, 9, (3), 2003, pPages 155-158Journal Article, 2003, DOI
- Sheils, O.M., Finn, S., O'Leary, J.J., Quality-control issues for PCR-based assays in the molecular laboratory , 9, (3), 2003, p165-172Journal Article, 2003, DOI
- Hackett, N.R., Sawy, T.B., Lee, L.Y., Silva, I., O'Leary, J., Rosengart, T.K., Crystal, R.G., Use of quantitative TaqMan real-time PCR to track the time-dependent distribution of gene transfer vectors in vivo , Molecular Therapy, 2, (6), 2000, p649-656Journal Article, 2000, DOI
- Sheils, O.M., O'Leary, J.J., Sweeney, E.C., Differentiation of multicentric origin from intra-organ metastatic spread of hepatocellular carcinomas by comparative genomic hybridization, Journal of Pathology, 192, (1), 2000, p43-51Journal Article, 2000, DOI
- Kennedy, M.M., Biddolph, S., Lucas, S.B., Howells, D.D., Picton, S., O'D McGee, J., O'Leary, J.J., CD40 upregulation is independent of HHV-8 in the pathogenesis of Kaposi's sarcoma , Journal of Clinical Pathology - Molecular Pathology, 52, (1), 1999, p32-36Journal Article, 1999, DOI
- O'Leary, J.J., Shapiro, R.L., Ren, C.J., Chuang, N., Cohen, H.W., Potmesil, M., Antiangiogenic effects of camptothecin analogues 9-amino- 20(S)camptothecin, topotecan, and CPT-11 studied in the mouse cornea model , Clinical Cancer Research, 5, (1), 1999, p181-187Journal Article, 1999, DOI
- O'Leary, J., Volm, M., Wasserheit, C., Muggia, F., Searching for Predictive Molecular Markers: Taxanes in Adjuvant and Neoadjuvant Therapies for Breast Cancer , Oncology Reports, 12, (1 SUPPL.1), 1998, p23-27Journal Article, 1998
- O'Leary, J.J., Landers, R.J., Silva, I., Uhlmann, V., Crowley, M., Healy, I., Luttich, K., Molecular analysis of ras oncogenes in CIN III and in stage I and II invasive squamous cell carcinoma of the uterine cervix , Journal of Clinical Pathology, 51, (8), 1998, p576-582Journal Article, 1998, DOI
- O'Leary, J., Muggia, F.M., Camptothecins: A review of their development and schedules of administration, European Journal of Cancer , 34, (10), 1998, p1500-1508Journal Article, 1998, DOI
- Uhlmann, V., Rolfs, A., Mix, E., Silva, I., Hully, J., Lu, L., Lohman, K., (...), O'Leary, J.J., A novel, rapid in cell RNA amplification technique for the detection of low copy mRNA transcripts, Journal of Clinical Pathology - Molecular Pathology, 51, (3), 1998, p160-163Journal Article, 1998, DOI
- Kennedy, M.M., O'Leary, J.J., Oates, J.L., Lucas, S.B., Howells, D.D., Picton, S., McGee, J.O'D., Human herpes virus 8 (HHV-8) in Kaposi's sarcoma: Lack of association with Bcl-2 and p53 protein expression , Journal of Clinical Pathology - Molecular Pathology, 51, (3), 1998, p155-159Journal Article, 1998, DOI
- Kennedy, M.M., Cooper, K., Howells, D.D., Picton, S., Biddolph, S., Lucas, S.B., McGee, J.O'D., O'Leary, J.J., Identification of HHV8 in early Kaposi's sarcoma: Implications for Kaposi's sarcoma pathogenesis , Journal of Clinical Pathology - Molecular Pathology, 51, (1), 1998, p14-20Journal Article, 1998, DOI
- O'Leary, J.J., Landers, R.J., Crowley, M., Healy, I., Kealy, W.F., Hogan, J., Doyle, C.T., Alterations in exon 1 of c-myc and expression of p62(c-myc) in cervical squamous cell carcinoma , Journal of Clinical Pathology , 50, (11), 1997, p896-903Journal Article, 1997, DOI
- O'Leary, J.J., Engels, K., Dada, M.A., The polymerase chain reaction in pathology , Journal of Clinical Pathology, 50, (10), 1997, p805-810Journal Article, 1997, URL
- O'Leary, J.J., Landers, R.J., Chetty, R., In situ amplification in cytological preparations , Cytopathology, 8, (3), 1997, p148-160Journal Article, 1997
- O'Leary, J.J., Seeking the cause of Kaposi's sarcoma , Nature Medicine, 2, (8), 1996, p862-863Journal Article, 1996, DOI
- O'Leary, J.J., Chetty, R., Graham, A.K., McGee, J.O'D., In situ PCR: Pathologist's dream or nightmare? , Journal of Pathology, 178, (1), 1996, p11-20Journal Article, 1996, DOI
- Chetty, R., Slavin, J.L., O'Leary, J.J., Ansari, N.A., Gatter, K.C., Primary Hodgkin's disease of the lung , Pathology, 27, (2), 1995, p111-114Journal Article, 1995, DOI
- O'Leary, J.J., Landers, R.J., Crowley, M., Healy, I., O'Donovan, M., Healy, V., Kealy, W.F., (...), Doyle, C.T., Human papillomavirus and mixed epithelial tumors of the endometrium , Human Pathology, 29, (4), 1998, p383-389Journal Article, 1998, DOI
- O'Leary, J.J., Silva, I., Uhlmann, V., Prasad, M., Luttich, K., Maffei, A., Picton, S., HHV-8 in multiple myeloma: Is this the first paracrine model of human tumorigenesis and do Koch's postulates apply? , Journal of Clinical Pathology - Molecular Pathology, 51, (4), 1998, p201-203Journal Article, 1998, URL
- Uhlmann, V., Silva, I., Luttich, K., Picton, S., O'Leary, J.J., In cell amplication , Journal of Clinical Pathology - Molecular Pathology, 51, (3), 1998, p119-130Journal Article, 1998, URL
- O'Leary, J.J., Kaposi's sarcoma associated herpes virus (KSHV/HHV 8) : Epidemiology, molecular biology and tissue distribution , Journal of Clinical Pathology - Molecular Pathology , 50, (1), 1997, p4-8Journal Article, 1997, URL
- Kennedy, M.M., Lucas, S.B., Russell-Jones, R., Howells, D.D., Picton, S.J., Bardon, A., Comley, I.L., (...), O'Leary, J.J., HHV8 and female Kaposi's sarcoma , Journal of Pathology, 183, (4), 1997, p447-452Journal Article, 1997, DOI
- Ely, S.A., Powers, J., Lewis, D., Chang, S., Rubio, A., O'Leary, J., Knowles, D.M., Kaposi's sarcoma-associated herpesvirus-positive primary effusion lymphoma arising in the subarachnoid space, Human Pathology, 30, (8), 1999, p981-984Journal Article, 1999, DOI
- Kennedy, M.M., Biddolph, S., Lucas, S.B., Howells, D.D., Picton, S., O'D McGee, J., Silva, I., (...), O'Leary, J.J., Cyclin D1 expression and HHV8 in Kaposi sarcoma , Journal of Clinical Pathology, 52, (8), 1999, p569-573Journal Article, 1999, DOI
- Prasad, M.L., Hyjek, E., Giri, D.D., Ying, L., O'Leary, J.J., Hoda, S.A., Double immunolabeling with cytokeratin and smooth-muscle actin in confirming early invasive carcinoma of breast , American Journal of Surgical Pathology, 23, (2), 1999, p176-181Journal Article, 1999, DOI
- Boshoff, C., Talbot, S., Kennedy, M., O'Leary, J., Schulz, T., Chang, Y., HHV8 and skin cancers in immunosuppressed patients. , Lancet, 348, (9020), 1996, p138Journal Article, 1996
- Koreth, J., O'Leary, J.J., McGee, J.O., Microsatellites and PCR genomic analysis , Journal of Pathology, 178, (3), 1996, p239-248Journal Article, 1996, DOI
- Chetty, R., O'Leary, J.J., Biddolph, S.C., Gatter, K.C., Immunohistochemical detection of p53 and Bcl-2 proteins in Hashimoto's thyroiditis and primary thyroid lymphomas , Journal of Clinical Pathology, 48, (3), 1995, p239-241Journal Article, 1995, DOI
- O'Leary, J.J., Browne, G., Johnson, M.I., Landers, R.J., Crowley, M., Healy, I., Street, J.T., (...), Doyle, C.T., PCR in situ hybridisation detection of HPV 16 in fixed CaSki and fixed SiHa cell lines, Journal of Clinical Pathology, 47, (10), 1994, p933-938Journal Article, 1994, DOI
- O'Leary, J.J., Browne, G., Landers, R., Crowley, M., Healy, I., Johnson, M.I., Doyle, C.T., New nucleic acid amplification techniques in diagnostic pathology, Journal of the European Academy of Dermatology and Venereology, 3, (1), 1994, p78-86Journal Article, 1994, DOI
- O'Leary, J.J., Browne, G., Landers, R.J., Crowley, M., Healy, I.B., Street, J.T., Pollock, A.M., (...), Doyle, C.T., The importance of fixation procedures on DNA template and its suitability for solution-phase polymerase chain reaction and PCR in situ hybridization , Histochemical Journal , 26, (4), 1994, p337-346Journal Article, 1994, DOI
- Landers, R.J., O'Leary, J.J., Crowley, M., Healy, I., Annis, P., Burke, L., O'Brien, D., (...), Doyle, C.T., Epstein-Barr virus in normal, pre-malignant, and malignant lesions of the uterine cervix , Journal of Clinical Pathology, 46, (10), 1993, p931-935Journal Article, 1993, DOI
- Doyle, C.T., O'Leary, J.J., The search for the universal fixative or 'magic juice' , Journal of Pathology , 166, (4), 1992, p331-332Journal Article, 1992, DOI
- Sheedy FJ, Palsson-McDermott E, Hennessy EJ, Martin C, O'Leary JJ, Ruan Q, Johnson DS, Chen Y, O'Neill LA., Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21, Nature Immunology, 11, (2), 2010, p141-147Journal Article, 2010, DOI
- Kelly JG, Cheung KT, Martin C, O'Leary JJ, Prendiville W, Martin-Hirsch PL, Martin FL, A spectral phenotype of oncogenic human papillomavirus-infected exfoliative cervical cytology distinguishes women based on age., Clinica chimica acta; international journal of clinical chemistry, 411, (15-16), 2010, p1027-1033Journal Article, 2010, DOI , URL
- Gallagher MF, Flavin RJ, Elbaruni SA, McInerney JK, Smyth PC, Salley YM, Vencken SF, O'Toole SA, Laios A, Lee MY, Denning K, Li J, Aherne ST, Lao KQ, Martin CM, Sheils OM, O'Leary JJ, Regulation of microRNA biosynthesis and expression in 2102Ep embryonal carcinoma stem cells is mirrored in ovarian serous adenocarcinoma patients., Journal of ovarian research, 2, 2009, p19Journal Article, 2009, DOI , URL , TARA - Full Text
- Baier T, Hansen-Hagge TE, Gransee R, Crombé A, Schmahl S, Paulus C, Drese KS, Keegan H, Martin C, O'Leary JJ, Furuberg L, Solli L, Grønn P, Falang IM, Karlgård A, Gulliksen A, Karlsen F, Hands-free sample preparation platform for nucleic acid analysis., Lab on a chip, 9, (23), 2009, p3399-405Journal Article, 2009, DOI , TARA - Full Text
- Mocanu E, Shattock R, Barton D, Rogers M, Conroy R, Sheils O, Collins C, Martin C, Harrison R, O'Leary J, All azoospermic males should be screened for cystic fibrosis mutations before intracytoplasmic sperm injection., Fertility and sterility, 2010Journal Article, 2010, DOI
- Flavin R, Jackl G, Finn S, Smyth P, Ring M, O'Regan E, Cahill S, Unger K, Denning K, Jinghuan Li Aherne S, Tallini G, Gaffney E, O'Leary JJ, Zitzelsberger H, Sheils O, RET/PTC rearrangement occurring in primary peritoneal carcinoma., International journal of surgical pathology, 17, (3), 2009, p187-97Journal Article, 2009, DOI
- Flavin R, Smyth P, Barrett C, Russell S, Wen H, Wei J, Laios A, O'Toole S, Ring M, Denning K, Li J, Aherne S, Sammarae D, Aziz NA, Alhadi A, Finn SP, Loda M, B S, Sheils O, O'Leary JJ, miR-29b expression is associated with disease-free survival in patients with ovarian serous carcinoma., International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 19, (4), 2009, p641-7Journal Article, 2009, DOI
- Ostrowska KM, Malkin A, Meade A, O'Leary J, Martin C, Spillane C, Byrne HJ, Lyng FM., Investigation of the influence of high-risk human papillomavirus on the biochemical composition of cervical cancer cells using vibrational spectroscopy., Analyst., (Oct 21), 2010Journal Article, 2010, DOI
- Oon SF, Watson RW, O'Leary JJ, Fitzpatrick JM, Epstein criteria for insignificant prostate cancer., BJU international, 2011Journal Article, 2011, DOI
- Ostrowska KM, Garcia A, Meade AD, Malkin A, Okewumi I, O'Leary JJ, Martin C, Byrne HJ, Lyng FM, Correlation of p16(INK4A) expression and HPV copy number with cellular FTIR spectroscopic signatures of cervical cancer cells., The Analyst, 136, (7), 2011, p1365-73Journal Article, 2011, DOI , URL , TARA - Full Text
- Astbury K, McEvoy L, Brian H, Spillane C, Sheils O, Martin C, O'Leary JJ, MYBL2 (B-MYB) in cervical cancer: putative biomarker., International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 21, (2), 2011, p206-12Journal Article, 2011, DOI
- O'Hurley G, O'Grady A, Smyth P, Byrne J, O'Leary JJ, Sheils O, Watson RW, Kay EW, Evaluation of Zinc-alpha-2-Glycoprotein and Proteasome Subunit beta-Type 6 Expression in Prostate Cancer Using Tissue Microarray Technology., Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry, 2010Journal Article, 2010, DOI
- Egan K, Crowley D, Smyth P, O'Toole S, Spillane C, Martin C, Gallagher M, Canney A, Norris L, Conlon N, McEvoy L, Ffrench B, Stordal B, Keegan H, Finn S, McEneaney V, Laios A, Ducrée J, Dunne E, Smith L, Berndt M, Sheils O, Kenny D, O'Leary J, Platelet Adhesion and Degranulation Induce Pro-Survival and Pro-Angiogenic Signalling in Ovarian Cancer Cells, PLoS ONE, 6, (10, e26125), 2011Journal Article, 2011, DOI , URL , TARA - Full Text
- O'Hurley G, Perry AS, O'Grady A, Loftus B, Smyth P, O'Leary JJ, Sheils O, Fitzpatrick JM, Hewitt SM, Lawler M, Kay EW, The role of secreted frizzled-related protein 2 expression in prostate cancer., Histopathology, 59, (6), 2011, p1240-1248Journal Article, 2011, DOI
- Murphy MA, O'Connell DJ, O'Kane SL, O'Brien JK, O'Toole S, Martin C, Sheils O, O'Leary JJ, Cahill DJ, Epitope presentation is an important determinant of the utility of antigens identified from protein arrays in the development of autoantibody diagnostic assays, Journal of Proteomics, 75, (15), 2012, p4668 - 4675Journal Article, 2012, DOI , URL , TARA - Full Text
- McSherry LA, Dombrowski SU, Francis JJ, Murphy J, Martin CM, O'Leary JJ, Sharp L, Group A, 'It's a can of worms': understanding primary care practitioners' behaviours in relation to HPV using the theoretical domains framework., Implementation science : IS, 7, (1), 2012, p73Journal Article, 2012
- Scharfe-Nugent A, Corr SC, Carpenter SB, Keogh L, Doyle B, Martin C, Fitzgerald KA, Daly S, O'Leary JJ, O'Neill LA, TLR9 provokes inflammation in response to fetal DNA: mechanism for fetal loss in preterm birth and preeclampsia., Journal of immunology (Baltimore, Md. : 1950), 188, (11), 2012Journal Article, 2012, DOI , TARA - Full Text
- Gallagher MF, Heffron CC, Laios A, O'Toole SA, Ffrench B, Smyth PC, Flavin RJ, Elbaruni SA, Spillane CD, Martin CM, Sheils OM, O'Leary JJ, Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples., Journal of ovarian research, 5, (1), 2012, p2Journal Article, 2012
- Martin CM, O'Leary JJ, Histology of cervical intraepithelial neoplasia and the role of biomarkers., Best practice & research. Clinical obstetrics & gynaecology, 25, (5), 2011, p605-15Journal Article, 2011, DOI
- Yusof A, Keegan H, Spillane CD, Sheils OM, Martin CM, O'Leary JJ, Zengerle R, Koltay P, Inkjet-like printing of single-cells., Lab on a chip, 11, (14), 2011, p2447-54Journal Article, 2011
- Gulliksen A, Keegan H, Martin C, O'Leary J, Solli LA, Falang IM, Grønn P, Karlgård A, Mielnik MM, Johansen IR, Tofteberg TR, Baier T, Gransee R, Drese K, Hansen-Hagge T, Riegger L, Koltay P, Zengerle R, Karlsen F, Ausen D, Furuberg L, Towards a "Sample-In, Answer-Out" Point-of-Care Platform for Nucleic Acid Extraction and Amplification: Using an HPV E6/E7 mRNA Model System., Journal of oncology, 2012, 2012, p905024Journal Article, 2012
- Laios A, Mohamed BM, Kelly L, Flavin R, Finn S, McEvoy L, Gallagher M, Martin C, Sheils O, Ring M, Davies A, Lawson M, Gleeson N, D'Arcy T, d'Adhemar C, Norris L, Langhe R, Saadeh FA, O'Leary JJ, O'Toole SA, Pre-Treatment of Platinum Resistant Ovarian Cancer Cells with an MMP-9/MMP-2 Inhibitor Prior to Cisplatin Enhances Cytotoxicity as Determined by High Content Screening., International journal of molecular sciences, 14, (1), 2013, p2085-103Journal Article, 2013, DOI , TARA - Full Text
- Tjalma WA, Fiander A, Reich O, Powell N, Nowakowski AM, Kirschner B, Koiss R, O'Leary J, Joura EA, Rosenlund M, Colau B, Schledermann D, Kukk K, Damaskou V, Repanti M, Vladareanu R, Kolomiets L, Savicheva A, Shipitsyna E, Ordi J, Molijn A, Quint W, Raillard A, Rosillon D, De Souza SC, Jenkins D, Holl K, Differences in human papillomavirus type distribution in high-grade cervical intraepithelial neoplasia and invasive cervical cancer in Europe., International journal of cancer. Journal international du cancer, 132, (4), 2013, p854-67Journal Article, 2013
- Murphy MA, O'Leary JJ, Cahill DJ, Assessment of the humoral immune response to cancer., Journal of proteomics, 75, (15), 2012, p4573-9Journal Article, 2012
- Dorris ER, Smyth P, O'Leary JJ, Sheils O, MIR141 Expression Differentiates Hashimoto Thyroiditis from PTC and Benign Thyrocytes in Irish Archival Thyroid Tissues., Frontiers in endocrinology, 3, 2012, p102Journal Article, 2012
- O'Flaherty JD, Gray S, Richard D, Fennell D, O'Leary JJ, Blackhall FH, O'Byrne KJ, Circulating tumour cells, their role in metastasis and their clinical utility in lung cancer., Lung cancer (Amsterdam, Netherlands), 76, (1), 2012, p19-25Journal Article, 2012, DOI
- Egan K, Crowley D, Smyth P, O'Toole S, Spillane C, Martin C, Gallagher M, Canney A, Norris L, Conlon N, McEvoy L, Ffrench B, Stordal B, Keegan H, Finn S, McEneaney V, Laios A, Ducrée J, Dunne E, Smith L, Berndt M, Sheils O, Kenny D, O'Leary J, Platelet adhesion and degranulation induce pro-survival and pro-angiogenic signalling in ovarian cancer cells., PloS one, 6, (10), 2011, pe26125Journal Article, 2011
- Logan C, Habington A, Lennon G, Grogan J, Byrne M, O'Leary J, O'Sullivan N, Genetic relatedness of Pseudomonas aeruginosa isolates among a paediatric cystic fibrosis patient cohort in Ireland., Journal of medical microbiology, 61, (Pt 1), 2012, p64-70Journal Article, 2012
- Flavin R, Finn SP, Choueiri TK, Ingoldsby H, Ring M, Barrett C, Rogers M, Smyth P, O'Regan E, Gaffney E, O'Leary JJ, Loda M, Signoretti S, Sheils O, RET protein expression in papillary renal cell carcinoma., Urologic oncology, 30, (6), 2012, p900-5Journal Article, 2012
- Grogan JA, Logan C, O'Leary J, Rush R, O'Sullivan N, Real-time PCR-based detection of Bordetella pertussis and Bordetella parapertussis in an Irish paediatric population., Journal of medical microbiology, 60, (Pt 6), 2011, p722-9Journal Article, 2011
- Cantwell-Dorris ER, O'Leary JJ, Sheils OM, BRAFV600E: implications for carcinogenesis and molecular therapy., Molecular cancer therapeutics, 10, (3), 2011, p385-94Journal Article, 2011
- Doherty B, Lawlor D, Gillet JP, Gottesman M, O'Leary JJ, Stordal B, Collateral Sensitivity to Cisplatin in KB-8-5-11 Drug-resistant Cancer Cells., Anticancer research, 34, (1), 2014, p503-7Journal Article, 2014, TARA - Full Text
- O'Brien CP, Taylor SE, O'Leary JJ, Finn SP, Molecular testing in oncology: Problems, pitfalls and progress., Lung cancer (Amsterdam, Netherlands), 2014Journal Article, 2014, DOI , TARA - Full Text
- O'Brien CP, Langabeer SE, O'Byrne KJ, O'Leary JJ, Finn SP, Predictive values for molecular diagnostics: converting unknown unknowns to known unknowns., Molecular diagnosis & therapy, 18, (1), 2014, p1-4Journal Article, 2014, DOI
- White C, Keegan H, Pilkington L, Ruttle C, Kerr P, Sharp L, O'Toole S, Turner M, Prendiville W, D'Arcy T, Fitzpatrick M, Lenehan P, Flannelly G, O'Leary JJ, Martin CM, Evaluation of the clinical performance of the cobas 4800 HPV test in patients referred for colposcopy., Journal of clinical microbiology, 51, (10), 2013, p3415-7Journal Article, 2013, DOI , TARA - Full Text
- Busschots,Steven S., O'Toole,Sharon A. S.A., O'Leary,John James J.J., Stordal,Britta K. B.K., Non-invasive and non-destructive measurements of confluence in cultured adherent cell lines, MethodsX, 2, 2015, p8-13Journal Article, 2015, DOI , TARA - Full Text
Research Expertise
Biomarkers of disease. Cervical Cancer. Development of array technologies. Molecular pathology. Prostate cancer.
Recognition
- Member, Centre for Molecular Research in Cancer (Proposed), This consortium combines researchers with common interest in understanding cell cycle signaling and regulation with specific focus on two key cancer-related processes (cell cycle control, apoptosis) and/or three specific malignancy types (oesophageal, prostate and haematological).
- Member, Core Technology PI's, DMMC Principal Investigators leading the development of core technology platforms.
- Member, DMMC Cancer Principal Investigators, Trans-institutional grouping of Principal Investigators leading research on Cancer themes
- Invitee, Breast Cancer Consortium (Proposed), Investigators to be invited to participate in Breast Cancer workshop with a view to establishing formal consortium and informal individual collaborations.Last updated : 19 November 2004. Extract from DMMC Research Database