Mercier S, Küry S, Salort-Campana E, Magot A, Agbim U, Besnard T, Bodak N, Bou-Hanna C, Bréhéret F, Brunelle P, Caillon F, Chabrol B, Cormier-Daire V, David A, Eymard B, Faivre L, Figarella-Branger D, Fleurence E, Ganapathi M, Gherardi R, Goldenberg A, Hamel A, Igual J, Irvine AD, Israël-Biet D, Kannengiesser C, Laboisse C, Le Caignec C, Mahé JY, Mallet S, MacGowan S, McAleer MA, McLean I, Méni C, Munnich A, Mussini JM, Nagy PL, Odel J, O'Regan GM, Péréon Y, Perrier J, Piard J, Puzenat E, Sampson JB, Smith F, Soufir N, Tanji K, Thauvin C, Ulane C, Watson RM, Khumalo NP, Mayosi BM, Barbarot S, Bézieau S, Expanding the clinical spectrum of hereditary fibrosing poikiloderma with tendon contractures, myopathy and pulmonary fibrosis due to FAM111B mutations., Orphanet journal of rare diseases, 10, 2015, p135Journal Article, 2015, DOI , TARA - Full Text
McAleer MA, Pohler E, Smith FJ, Wilson NJ, Cole C, MacGowan S, Koetsier JL, Godsel LM, Harmon RM, Gruber R, Crumrine D, Elias PM, McDermott M, Butler K, Broderick A, Sarig O, Sprecher E, Green KJ, McLean WH, Irvine AD, Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin., The Journal of allergy and clinical immunology, 2015Journal Article, 2015, DOI , TARA - Full Text
Riethmuller C, McAleer MA, Koppes SA, Abdayem R, Franz J, Haftek M, Campbell LE, MacCallum SF, McLean WH, Irvine AD, Kezic S, Filaggrin breakdown products determine corneocyte conformation in patients with atopic dermatitis., The Journal of allergy and clinical immunology, 2015Journal Article, 2015, DOI , TARA - Full Text
Kelleher M, Dunn-Galvin A, Hourihane JO, Murray D, Campbell LE, McLean WH, Irvine AD, Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year., The Journal of allergy and clinical immunology, 135, (4), 2015, p930-5.e1Journal Article, 2015, DOI , TARA - Full Text
Baurecht H, Hotze M, Brand S, Büning C, Cormican P, Corvin A, Ellinghaus D, Ellinghaus E, Esparza-Gordillo J, Fölster-Holst R, Franke A, Gieger C, Hubner N, Illig T, Irvine AD, Kabesch M, Lee YA, Lieb W, Marenholz I, McLean WH, Morris DW, Mrowietz U, Nair R, Nöthen MM, Novak N, O'Regan GM, Schreiber S, Smith C, Strauch K, Stuart PE, Trembath R, Tsoi LC, Weichenthal M, Barker J, Elder JT, Weidinger S, Cordell HJ, Brown SJ, Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms., American journal of human genetics, 96, (1), 2015, p104-20Journal Article, 2015, DOI , TARA - Full Text
O'Regan GM, Kemperman PM, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Rowland M, Puppels GJ, McLean WH, Caspers PJ, Irvine AD, Raman profiles of the stratum corneum define 3 filaggrin genotype-determined atopic dermatitis endophenotypes., The Journal of allergy and clinical immunology, 126, (3), 2010, p574-80.e1Journal Article, 2010
Bergboer JG, Zeeuwen PL, Irvine AD, Weidinger S, Giardina E, Novelli G, Den Heijer M, Rodriguez E, Illig T, Riveira-Munoz E, Campbell LE, Tyson J, Dannhauser EN, O'Regan GM, Galli E, Klopp N, Koppelman GH, Novak N, Estivill X, McLean WH, Postma DS, Armour JA, Schalkwijk J, Deletion of Late Cornified Envelope 3B and 3C genes is not associated with atopic dermatitis., The Journal of investigative dermatology, 130, (8), 2010, p2057-61Journal Article, 2010
O'Regan GM, Campbell LE, Cordell HJ, Irvine AD, McLean WH, Brown SJ, Chromosome 11q13.5 variant associated with childhood eczema: an effect supplementary to filaggrin mutations., The Journal of allergy and clinical immunology, 125, (1), 2010, p170-4.e1-2Journal Article, 2010
Sun M, Li N, Dong W, Chen Z, Liu Q, Xu Y, He G, Shi Y, Li X, Hao J, Luo Y, Shang D, Lv D, Ma F, Zhang D, Hua R, Lu C, Wen Y, Cao L, Irvine AD, McLean WH, Dong Q, Wang MR, Yu J, He L, Lo WH, Zhang X, Copy-number mutations on chromosome 17q24.2-q24.3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasia., American journal of human genetics, 84, (6), 2009, p807-13Journal Article, 2009
McLean WH, Irvine AD, Hamill KJ, Whittock NV, Coleman-Campbell CM, Mellerio JE, Ashton GS, Dopping-Hepenstal PJ, Eady RA, Jamil T, Phillips R, Shabbir SG, Haroon TS, Khurshid K, Moore JE, Page B, Darling J, Atherton DJ, Van Steensel MA, Munro CS, Smith FJ, McGrath JA, Phillips RJ, An unusual N-terminal deletion of the laminin alpha3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome., Human molecular genetics, 12, (18), 2003, p2395-409Journal Article, 2003
Terron-Kwiatkowski A, Paller AS, Compton J, Atherton DJ, McLean WH, Irvine AD, Two cases of primarily palmoplantar keratoderma associated with novel mutations in keratin 1., The Journal of investigative dermatology, 119, (4), 2002, p966-71Journal Article, 2002
Bitoun E, Chavanas S, Irvine AD, Lonie L, Bodemer C, Paradisi M, Hamel-Teillac D, Ansai S, Mitsuhashi Y, Taïeb A, de Prost Y, Zambruno G, Harper JI, Hovnanian A, Netherton syndrome: disease expression and spectrum of SPINK5 mutations in 21 families., The Journal of investigative dermatology, 118, (2), 2002, p352-61Journal Article, 2002
McGrath JA, Duijf PH, Doetsch V, Irvine AD, de Waal R, Vanmolkot KR, Wessagowit V, Kelly A, Atherton DJ, Griffiths WA, Orlow SJ, van Haeringen A, Ausems MG, Yang A, McKeon F, Bamshad MA, Brunner HG, Hamel BC, van Bokhoven H, Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63., Human molecular genetics, 10, (3), 2001, p221-9Journal Article, 2001
Korge BP, Hamm H, Jury CS, Traupe H, Irvine AD, Healy E, Birch-MacHin M, Rees JL, Messenger AG, Holmes SC, Parry DA, Munro CS, Identification of novel mutations in basic hair keratins hHb1 and hHb6 in monilethrix: implications for protein structure and clinical phenotype., The Journal of investigative dermatology, 113, (4), 1999, p607-12Journal Article, 1999
Casey M, Mah C, Merliss AD, Kirschner LS, Taymans SE, Denio AE, Korf B, Irvine AD, Hughes A, Carney JA, Stratakis CA, Basson CT, Identification of a novel genetic locus for familial cardiac myxomas and Carney complex., Circulation, 98, (23), 1998, p2560-6Journal Article, 1998
Ahmad W, Irvine AD, Lam H, Buckley C, Bingham EA, Panteleyev AA, Ahmad M, McGrath JA, Christiano AM, A missense mutation in the zinc-finger domain of the human hairless gene underlies congenital atrichia in a family of Irish travellers., American journal of human genetics, 63, (4), 1998, p984-91Journal Article, 1998
Irvine AD, McKenna KE, Bingham A, Nevin NC, Hughes AE, A novel mutation in the helix termination peptide of keratin 5 causing epidermolysis bullosa simplex Dowling-Meara., The Journal of investigative dermatology, 109, (6), 1997, p815-6Journal Article, 1997
Irvine AD, Dolan OM, Hadden DR, Stewart FJ, Bingham EA, Nevin NC, An autosomal dominant syndrome of acromegaloid facial appearance and generalised hypertrichosis terminalis., Journal of medical genetics, 33, (11), 1996, p972-4Journal Article, 1996
Higgins E, Capra M, Schwartz ME, Smith FJD, McLean WHI, Irvine AD, Resolution of the plantar hyperkeratosis of pachyonychia congenita during chemotherapy for Ewing sarcoma , British Journal of Dermatology , 169 , (6 ), 2013, p1357 - 1360Journal Article, 2013, TARA - Full Text
Sandilands Aileen, Brown Sara J, Goh Christabelle S, Pohler Elizabeth, Wilson Neil J, Campbell Linda E, Miyamoto Kenichi, Kubo Akiharu, Irvine Alan D, Thawer-Esmail Fatema, Mutations in the SASPase gene (ASPRV1) are not associated with atopic eczema or clinically dry skin , The Journal of investigative dermatology , 132 , (5 ), 2012, p1507 -Journal Article, 2012, TARA - Full Text
Hussain Safia, Berki Dorottya M., Choon Siew-Eng, Burden A. David, Allen Michael H., Arostegui Juan I., Chaves Antonio, Duckworth Michael, Irvine Alan D., Mockenhaupt Maja, Navarini Alexander A., Seyger Marieke M.B., Soler-Palacin Pere, Prins Christa, Valeyrie-Allanore Laurence, Vicente M. Asuncion, Trembath Richard C., Smith Catherine H., Barker Jonathan N., Capon Francesca, IL36RN mutations define a severe autoinflammatory phenotype of generalized pustular psoriasis , Journal of Allergy and Clinical Immunology , 135 , (4 ), 2015, p1067 - 1070.e9Journal Article, 2015, DOI , URL , TARA - Full Text
Connor S, O'Brien M, Irvine A, O'Marcaigh A, Smith O, C3-C4 shingles post haematopoietic stem-cell transplantation., 2015Journal Article, 2015
Wedgeworth E, Glover M, Irvine AD, Neri I, Baselga Torres E, Clayton TH, Beattie PE, Bjerre JV, Burrows NP, Foelster-Holst R, Hedelund L, Hernandez-Martin A, Audrain H, Bhate K, Brown SJ, Baryschpolec S, Darne S, Durack A, Dvorakova V, Gach J, Goldstraw N, Goodyear H, Grabcyznska S, Greenblatt D, Halpern J, Hearn RM, Hoey S, Hughes B, Jayaraj R, Johansson EK, Lam M, Leech S, O'Regan GM, Morrison D, Porter W, Ramesh R, Schill T, Shaw L, Taylor AE, Taylor R, Thomson J, Tiffin P, Tsakok M, Janmohamed SR, Laguda B, McPherson T, Oranje A, Patrizi A, Ravenscroft J, Shahidullah H, Soloman L, Svensson A, Wahlgren CF, Hoeger PH, Flohr C, Propranolol in the treatment of infantile haemangiomas: Lessons from the European Propranolol In the Treatment of Complicated Haemangiomas (PITCH) Taskforce Survey., The British journal of dermatology, 2015Journal Article, 2015, DOI , TARA - Full Text
Irvine AD, Commentary: Methotrexate and ciclosporin in the treatment of severe eczema in children., The British journal of dermatology, 170, (3), 2014, p499-500Journal Article, 2014, DOI , TARA - Full Text
Kiely C, Devaney D, Fischer J, Lenane P, Irvine AD, Ichthyosis prematurity syndrome: a case report and review of known mutations., Pediatric dermatology, 31, (4), 2014, p517-8Journal Article, 2014, DOI , TARA - Full Text
Berki DM, Liu L, Choon SE, Burden AD, Griffiths CE, Navarini AA, Tan ES, Irvine AD, Ranki A, Ogo T, Petrof G, Mahil SK, Duckworth M, Allen MH, Vito P, Trembath RC, McGrath J, Smith CH, Capon F, Barker JN, Activating CARD14 Mutations Are Associated with Generalized Pustular Psoriasis but Rarely Account for Familial Recurrence in Psoriasis Vulgaris., The Journal of investigative dermatology, 135, (12), 2015, p2964-70Journal Article, 2015, DOI , TARA - Full Text
Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, Young GT, Weiss C, Schabhüttl M, Stucka R, Schmid AB, Parman Y, Graul-Neumann L, Heinritz W, Passarge E, Watson RM, Hertz JM, Moog U, Baumgartner M, Valente EM, Pereira D, Restrepo CM, Katona I, Dusl M, Stendel C, Wieland T, Stafford F, Reimann F, von Au K, Finke C, Willems PJ, Nahorski MS, Shaikh SS, Carvalho OP, Nicholas AK, Karbani G, McAleer MA, Cilio MR, McHugh JC, Murphy SM, Irvine AD, Jensen UB, Windhager R, Weis J, Bergmann C, Rautenstrauss B, Baets J, De Jonghe P, Reilly MM, Kropatsch R, Kurth I, Chrast R, Michiue T, Bennett DL, Woods CG, Senderek J, Transcriptional regulator PRDM12 is essential for human pain perception., Nature genetics, 47, (7), 2015, p803-8Journal Article, 2015, DOI , TARA - Full Text
O'Donovan SM, O'B Hourihane J, Murray DM, Kenny LC, Khashan AS, Chaoimh CN, Irvine AD, Kiely M, Neonatal adiposity increases the risk of atopic dermatitis during the first year of life., The Journal of allergy and clinical immunology, 137, (1), 2016, p108-17Journal Article, 2016, DOI , TARA - Full Text
Kelleher MM, Dunn-Galvin A, Gray C, Murray DM, Kiely M, Kenny L, McLean WH, Irvine AD, Hourihane JO, Skin barrier impairment at birth predicts food allergy at 2 years of age., The Journal of allergy and clinical immunology, 2016Journal Article, 2016, DOI , TARA - Full Text
Dvorakova V, Watson RM, Terron-Kwiatkowski A, Andrew N, Irvine AD, Congenital reticular ichthyosiform erythroderma., Clinical and experimental dermatology, 2016Journal Article, 2016, DOI , TARA - Full Text
Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, Strachan DP, Curtin JA, Bønnelykke K, Tian C, Takahashi A, Esparza-Gordillo J, Alves AC, Thyssen JP, den Dekker HT, Ferreira MA, Altmaier E, Sleiman PM, Xiao FL, Gonzalez JR, Marenholz I, Kalb B, Pino-Yanes M, Xu CJ, Carstensen L, Groen-Blokhuis MM, Venturini C, Pennell CE, Barton SJ, Levin AM, Curjuric I, Bustamante M, Kreiner-Møller E, Lockett GA, Bacelis J, Bunyavanich S, Myers RA, Matanovic A, Kumar A, Tung JY, Hirota T, Kubo M, McArdle WL, Henderson AJ, Kemp JP, Zheng J, Smith GD, Rüschendorf F, Bauerfeind A, Lee-Kirsch MA, Arnold A, Homuth G, Schmidt CO, Mangold E, Cichon S, Keil T, Rodríguez E, Peters A, Franke A, Lieb W, Novak N, Fölster-Holst R, Horikoshi M, Pekkanen J, Sebert S, Husemoen LL, Grarup N, de Jongste JC, Rivadeneira F, Hofman A, Jaddoe VW, Pasmans SG, Elbert NJ, Uitterlinden AG, Marks GB, Thompson PJ, Matheson MC, Robertson CF, Ried JS, Li J, Zuo XB, Zheng XD, Yin XY, Sun LD, McAleer MA, O'Regan GM, Fahy CM, Campbell L, Macek M, Kurek M, Hu D, Eng C, Postma DS, Feenstra B, Geller F, Hottenga JJ, Middeldorp CM, Hysi P, Bataille V, Spector T, Tiesler CM, Thiering E, Pahukasahasram B, Yang JJ, Imboden M, Huntsman S, Vilor-Tejedor N, Relton CL, Myhre R, Nystad W, Custovic A, Weiss ST, Meyers DA, Söderhäll C, Melén E, Ober C, Raby BA, Simpson A, Jacobsson B, Holloway JW, Bisgaard H, Sunyer J, Probst-Hensch NM, Williams LK, Godfrey KM, Wang CA, Boomsma DI, Melbye M, Koppelman GH, Jarvis D, McLean WH, Irvine AD, Zhang XJ, Hakonarson H, Gieger C, Burchard EG, Martin NG, Duijts L, Linneberg A, Jarvelin MR, Nöthen MM, Lau S, Hübner N, Lee YA, Tamari M, Hinds DA, Glass D, Brown SJ, Heinrich J, Evans DM, Weidinger S, Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis., Nature genetics, 47, (12), 2015, p1449-56Journal Article, 2015, DOI , TARA - Full Text
Courtney DG, Atkinson SD, Allen EH, Moore JE, Walsh CP, Pedrioli DM, MacEwen CJ, Pellegrini G, Maurizi E, Serafini C, Fantacci M, Liao H, Irvine AD, McLean WH, Moore CB, siRNA silencing of the mutant keratin 12 allele in corneal limbal epithelial cells grown from patients with Meesmann's epithelial corneal dystrophy., Investigative ophthalmology & visual science, 55, (5), 2014, p3352-60Journal Article, 2014, DOI , TARA - Full Text
Satveer K. Mahil, Sophie Twelves, Katalin Farkas, Niovi Setta-Kaffetzi, A. David Burden, Joanna E. Gach, Alan D. Irvine, László Képíró, Maja Mockenhaupt, Hazel H. Oon, Jason Pinner, Annamari Ranki, Marieke M.B. Seyger, Pere Soler-Palacin, Eoin R. Storan, Eugene S. Tan, Laurence Valeyrie-Allanore, Helen S. Young, Richard C. Trembath, Siew-Eng Choon, Marta Szell, Zsuzsanna Bata-Csorgo, Catherine H. Smith, Paola Di Meglio, Jonathan N. Barker, Francesca Capon, AP1S3 Mutations Cause Skin Autoinflammation by Disrupting Keratinocyte Autophagy and Up-Regulating IL-36 Production, Journal of Investigative Dermatology, 136, (11), 2016, p2251--2259Journal Article, 2016
Jessica Strid, W.H. Irwin McLean, Alan D. Irvine, Too Much, Too Little or Just Enough: A Goldilocks Effect for IL-13 and Skin Barrier Regulation?, Journal of Investigative Dermatology, 136, (3), 2016, p561--564Journal Article, 2016
Bieber, T., Akdis, C., Lauener, R., Traidl-Hoffmann, C., Schmid-Grendelmeier, P., Schäppi, G., Allam, J.-P., Apfelbacher, C., Augustin, M., Beck, L., Biedermann, T., Braun-Fahrländer, C., Chew, F.T., Clavel, T., Crameri, R., Darsow, U., Deleuran, M., Dittlein, D., Duchna, H.-W., Eichenfeld, L., Eyerich, K., Frei, R., Gelmetti, C., Gieler, U., Gilles, S., Glatz, M., Grando, K., Green, J., Gutermuth, J., Guttman-Yassky, E., Hanifin, J., Hijnen, D., Hoetzenecker, W., Irvine, A., Kalweit, A., Katoh, N., Knol, E., Koren, H., Möhrenschlager, M., Münch, D., Novak, N., O'Mahony, L., Paller, A.S., Rhyner, C., Roduit, C., Schiesser, K., Schröder, J., Simon, D., Simon, H.-U., Sokolowska, M., Spuls, P., Stalder, J.-F., Straub, D., Szalai, Z., Taieb, A., Takaoka, R., Todd, G., Todorova, A., Vestergaard, C., Werfel, T., Wollenberg, A., Ring, J., Global Allergy Forum and 3rd Davos Declaration 2015: Atopic dermatitis/Eczema: Challenges and opportunities toward precision medicine, Allergy: European Journal of Allergy and Clinical Immunology, 71, (5), 2016, p588-592Journal Article, 2016
Hussain, S., Berki, D.M., Choon, S.-E., Burden, A.D., Allen, M.H., Arostegui, J.I., Chaves, A., Duckworth, M., Irvine, A.D., Mockenhaupt, M., Navarini, A.A., Seyger, M.M.B., Soler-Palacin, P., Prins, C., Valeyrie-Allanore, L., Vicente, M.A., Trembath, R.C., Smith, C.H., Barker, J.N., Capon, F., IL36RN mutations define a severe autoinflammatory phenotype of generalized pustular psoriasis: To the editor, Journal of Allergy and Clinical Immunology, 135, (4), 2015, p1067-1070.e9Journal Article, 2015
O'Rafferty, C., O'Regan, G.M., Irvine, A.D., Smith, O.P., Kasabach-Merritt syndrome, kaposiform haemangioendothelioma and platelet blockade, British Journal of Haematology, 2015Journal Article, 2015
O'Rafferty, C., O'Regan, G.M., Irvine, A.D., Smith, O.P., Recent advances in the pathobiology and management of Kasabach-Merritt phenomenon, British Journal of Haematology, 2015Journal Article, 2015
Higgins, E., Al Shehri, T., McAleer, M.A., Conlon, N., Feighery, C., Lilic, D., Irvine, A.D., Use of ruxolitinib to successfully treat chronic mucocutaneous candidiasis caused by gain-of-function signal transducer and activator of transcription 1 (STAT1) mutation, Journal of Allergy and Clinical Immunology, 135, (2), 2015, p551-553Journal Article, 2015
Gallagher, A., Hourihane, J.O.B., Kenny, L.C., Irvine, A.D., Khashan, A.S., A longitudinal study of skin barrier function in pregnancy and the postnatal period, Obstetric Medicine, 7, (4), 2014, p156-159Journal Article, 2014
Hughes, R., McAleer, M., Watson, R., Collins, S., Irvine, A., White, M., Rapidly involuting congenital hemangioma with pustules: Two cases, Pediatric Dermatology, 31, (3), 2014, p398-400Journal Article, 2014
Salinas, C.F., Irvine, A.D., Itin, P.H., Di Giovanna, J.J., Schneider, H., Clarke, A.J., McGovern, L.S., Fete, M., Second international conference on a classification of ectodermal dysplasias: Development of a multiaxis model, American Journal of Medical Genetics, Part A, 164, (10), 2014, p2482-2489Journal Article, 2014
Courtney, D.G., Atkinson, S.D., Allen, E.H.A., Moore, J.E., Walsh, C.P., Pedrioli, D.M.L., MacEwen, C.J., Pellegrini, G., Maurizi, E., Serafini, C., Fantacci, M., Liao, H., Irvine, A.D., McIrwin Lean, W.H., Tara Moore, C.B., SiRNA silencing of the mutant keratin 12 allele in corneal limbal epithelial cells grown from patients with Meesmann's epithelial corneal dystrophy, Investigative Ophthalmology and Visual Science, 55, (5), 2014, p3352-3360Journal Article, 2014
Baclig, A.C., Bakker Schut, T.C., O'Regan, G.M., Irvine, A.D., McLean, W.H.I., Puppels, G.J., Caspers, P.J., Possibilities for human skin characterization based on strongly reduced Raman spectroscopic information, Journal of Raman Spectroscopy, 44, (3), 2013, p340-345Journal Article, 2013
Keohane, C., Bacon, C.L., Moran, B., Irvine, A.D., Smith, O.P., Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome induced by cidofovir, Pediatric Transplantation, 15, (1), 2011Journal Article, 2011
Sais, G., Vidaller, A., Jucgla, A., Gallardo, F., Peyri, J., Irvine, A.D., Bruce, I.N., Antineutrophil cytoplasmic antibodies in leukocytoclastic vasculitis [1] (multiple letters), Archives of Dermatology, 134, (2), 1998, p239-240Journal Article, 1998
O'Hagan, A.H., Irvine, A.D., Allen, G.E., Walsh, M., Pseudoporphyria induced by mefenamic acid [16], British Journal of Dermatology, 139, (6), 1998, p1131-1132Journal Article, 1998
Weidinger, S., Irvine, A.D., Genetics of Atopic Dermatitis, Harper's Textbook of Pediatric Dermatology: Third Edition, 1, 2011, p1-17Journal Article, 2011
Irvine, A.D., Hoeger, P.H., Yan, A.C., Harper's Textbook of Pediatric Dermatology: Third Edition, Harper's Textbook of Pediatric Dermatology: Third Edition, 1-2, 2011Journal Article, 2011
Irvine, A.D., Bruce, I.N., Walsh, M., Burrows, D., Handley, J., Dermatological presentation of disease associated with antineutrophil cytoplasmic antibodies: A report of two contrasting cases and a review of the literature, British Journal of Dermatology, 134, (5), 1996, p924-928Journal Article, 1996
Moriarty, B., Bourke, J.F., Fitzgibbon, J., Irvine, A.D., An unusual rash in a neonate, Clinical and Experimental Dermatology, 35, (3), 2010Journal Article, 2010
Wen, Y., Liu, Y., Xu, Y., Zhao, Y., Hua, R., Wang, K., Sun, M., Li, Y., Yang, S., Zhang, X.-J., Kruse, R., Cichon, S., Betz, R.C., Nöthen, M.M., Van Steensel, M.A.M., Van Geel, M., Steijlen, P.M., Hohl, D., Huber, M., Dunnill, G.S., Kennedy, C., Messenger, A., Munro, C.S., Terrinoni, A., Hovnanian, A., Bodemer, C., De Prost, Y., Paller, A.S., Irvine, A.D., Sinclair, R., Green, J., Shang, D., Liu, Q., Luo, Y., Jiang, L., Chen, H.-D., Lo, W.H.-Y., McLean, W.H.I., He, C.-D., Zheng, X., Erratum: Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis (Nature Genetics (2009) 41 (228-233)), Nature Genetics, 41, (6), 2009Journal Article, 2009
O'Regan, G.M., Canny, G., Irvine, A.D., 'Peeling paint' dermatitis as a presenting sign of cystic fibrosis, Journal of Cystic Fibrosis, 5, (4), 2006, p257-259Journal Article, 2006
Smith, F.J.D., Irvine, A.D., Terron-Kwiatkowski, A., Sandilands, A., Campbell, L.E., Zhao, Y., Liao, H., Evans, A.T., Goudie, D.R., Lewis-Jones, S., Arseculeratne, G., Munro, C.S., Sergeant, A., O'Regan, G., Bale, S.J., Compton, J.G., Digiovanna, J.J., Presland, R.B., Fleckman, P., McLean, W.H.I., Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris, Nature Genetics, 38, (3), 2006, p337-342Journal Article, 2006
McLean, W.H.I., Irvine, A.D., Hamill, K.J., Whittock, N.V., Coleman-Campbell, C.M., Mellerio, J.E., Ashton, G.S., Dopping-Hepenstal, P.J.H., Eady, R.A.J., Jamil, T., Phillips, R.J., Ghulam Shabbir, S., Haroon, T.S., Khurshid, K., Moore, J.E., Page, B., Darling, J., Atherton, D.J., van Steensel, M.A.M., Munro, C.S., Smith, F.J.D., McGrath, J.A., Erratum: An unusual N-terminal deletion of the laminin "3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome (Human Molecular Genetics (2003) vol. 12 (2395-2409)), Human Molecular Genetics, 13, (3), 2004Journal Article, 2004
Irvine, A.D., McLean, W.H.I., The molecular genetics of the genodermatoses: Progress to date and future directions, British Journal of Dermatology, 148, (1), 2003, p1-13Journal Article, 2003
Irvine, A.D., Paller, A.S., Molecular genetics of the inherited disorders of cornification: an update., Advances in dermatology, 18, 2002, p111-149Journal Article, 2002
O"Donovan, S.M., Murray, D.M., Hourihane, J.O., Kenny, L.C., Irvine, A.D., Kiely, M., Adherence with early infant feeding and complementary feeding guidelines in the Cork BASELINE Birth Cohort Study, Public Health Nutrition, 2015Journal Article, 2015
Purcell, C., Cant, A., Irvine, A.D., DOCK8 primary immunodeficiency syndrome, The Lancet, 2015Journal Article, 2015
Chen, Y.-C., Auer-Grumbach, M., Matsukawa, S., Zitzelsberger, M., Themistocleous, A.C., Strom, T.M., Samara, C., Moore, A.W., Cho, L.T.-Y., Young, G.T., Weiss, C., Schabhüttl, M., Stucka, R., Schmid, A.B., Parman, Y., Graul-Neumann, L., Heinritz, W., Passarge, E., Watson, R.M., Hertz, J.M., Moog, U., Baumgartner, M., Valente, E.M., Pereira, D., Restrepo, C.M., Katona, I., Dusl, M., Stendel, C., Wieland, T., Stafford, F., Reimann, F., Von Au, K., Finke, C., Willems, P.J., Nahorski, M.S., Shaikh, S.S., Carvalho, O.P., Nicholas, A.K., Karbani, G., McAleer, M.A., Cilio, M.R., McHugh, J.C., Murphy, S.M., Irvine, A.D., Jensen, U.B., Windhager, R., Weis, J., Bergmann, C., Rautenstrauss, B., Baets, J., De Jonghe, P., Reilly, M.M., Kropatsch, R., Kurth, I., Chrast, R., Michiue, T., Bennett, D.L.H., Woods, C.G., Senderek, J., Erratum: Transcriptional regulator PRDM12 is essential for human pain perception (Nature Genetics (2015) 47 (803-808)), Nature Genetics, 47, (8), 2015Journal Article, 2015
Janna Nousbeck, Alan D. Irvine, Atopic Dermatitis According to GARP: New Mechanistic Insights in Disease Pathogenesis, Journal of Investigative Dermatology, 136, (12), 2016, p2340--2341Journal Article, 2016
O'Donovan SM, Murray DM, Hourihane JO, Kenny LC, Irvine AD, Kiely M, Cohort profile: The Cork BASELINE Birth Cohort Study: Babies after SCOPE: Evaluating the Longitudinal Impact on Neurological and Nutritional Endpoints., 2015Journal Article, 2015
O"Donovan SM, Murray DM, Hourihane JO, Kenny LC, Irvine AD, Kiely M, No association between food allergens in the complementary feeding diet and eczema during the first 12-months in the Cork BASELINE Birth Cohort., 2015Journal Article, 2015
Oosthuizen L, Mc Aleer MA, Watson RM, O"Regan GM, Byrne A, Crispino-O"Connell G, Irvine AD, Nottingham Eczema Severity Scoring tool can identify children at high risk of food allergy to cow"s milk, egg and peanut., 2015Journal Article, 2015
Kelleher M, Dunn AG, Irvine A, Smith H, Hourihane OJ, O08 - Increased early life Transepidermal Water Loss (TEWL) values can predate atopic dermatitis in asymptomatic infants: results from the BASELINE study., 2014Journal Article, 2014
Schmitt J, Schwarz K, Baurecht H, Hotze M, Fölster-Holst R, Rodríguez E, Lee YA, Franke A, Degenhardt F, Lieb W, Gieger C, Kabesch M, Nöthen MM, Irvine AD, McLean WH, Deckert S, Stephan V, Schwarz P, Aringer M, Novak N, Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes., 2016Journal Article, 2016
Gerbens, L.A.A., Boyce, A.E., Wall, D., Barbarot, S., Booij, R.J., Deleuran, M., Middelkamp-Hup, M.A., Roberts, A., Vestergaard, C., Weidinger, S., Apfelbacher, C.J., Irvine, A.D., Schmitt, J., Williamson, P.R., Spuls, P.I., Flohr, C., TREatment of ATopic eczema (TREAT) Registry Taskforce: Protocol for an international Delphi exercise to identify a core set of domains and domain items for national atopic eczema registries, Trials, 18, (1), 2017Journal Article, 2017
Kiely, M., O'Donovan, S.M., Kenny, L.C., Hourihane, J.O., Irvine, A.D., Murray, D.M., Vitamin D metabolite concentrations in umbilical cord blood serum and associations with clinical characteristics in a large prospective mother-infant cohort in Ireland, Journal of Steroid Biochemistry and Molecular Biology, 167, 2017, p162-168Journal Article, 2017
Hawkes, C.P., Zemel, B.S., Kiely, M., Irvine, A.D., Kenny, L.C., O'B Hourihane, J., Murray, D.M., Body composition within the first 3 months: Optimized correction for length and correlation with BMI at 2 Years, Hormone Research in Paediatrics, 86, (3), 2016, p178-187Journal Article, 2016
Chaoimh, C., Murray, D.M., Kenny, L.C., Irvine, A.D., O'Hourihane, J.B., Kiely, M., Cord blood leptin and gains in body weight and fat mass during infancy, European Journal of Endocrinology, 175, (5), 2016, p403-410Journal Article, 2016
Storan, E.R., Irvine, A.D., Access to Genetic Diagnostics for Genodermatoses: Who Should Get Tested? Why? Who Pays?, Pediatric Dermatology, 34, (1), 2017, p105-108Journal Article, 2017
Soblet, J., Kangas, J., Nätynki, M., Mendola, A., Helaers, R., Uebelhoer, M., Kaakinen, M., Cordisco, M., Dompmartin, A., Enjolras, O., Holden, S., Irvine, A.D., Kangesu, L., Léauté-Labrèze, C., Lanoel, A., Lokmic, Z., Maas, S., McAleer, M.A., Penington, A., Rieu, P., Syed, S., van der Vleuten, C., Watson, R., Fishman, S.J., Mulliken, J.B., Eklund, L., Limaye, N., Boon, L.M., Vikkula, M., Blue Rubber Bleb Nevus (BRBN) Syndrome Is Caused by Somatic TEK (TIE2) Mutations, Journal of Investigative Dermatology, 137, (1), 2017, p207-216Journal Article, 2017
Gilhooley, E., Gormally, S., Irvine, A., Lynch, S.A., Collins, S., FOXN1 Duplication and Congenital Hypertrichosis, Pediatric Dermatology, 34, (2), 2017, pe77-e79Journal Article, 2017
Samuelov, L., Li, Q., Bochner, R., Najor, N.A., Albrecht, L., Malchin, N., Goldsmith, T., Grafi-Cohen, M., Vodo, D., Fainberg, G., Meilik, B., Goldberg, I., Warshauer, E., Rogers, T., Edie, S., Ishida-Yamamoto, A., Burzenski, L., Erez, N., Murray, S.A., Irvine, A.D., Shultz, L., Green, K.J., Uitto, J., Sprecher, E., Sarig, O., SVEP1 plays a crucial role in epidermal differentiation, Experimental Dermatology, 2017Journal Article, 2017
Mccarthy, E.K., ní Chaoimh, C., O'B Hourihane, J., Kenny, L.C., Irvine, A.D., Murray, D.M., Kiely, M., Iron intakes and status of 2-year-old children in the Cork BASELINE Birth Cohort Study, Maternal and Child Nutrition, 2016Journal Article, 2016
Ní Chaoimh, C., McCarthy, E.K., Hourihane, J.O., Kenny, L.C., Irvine, A.D., Murray, D.M., Kiely, M.E., Low vitamin D deficiency in Irish toddlers despite northerly latitude and a high prevalence of inadequate intakes, European Journal of Nutrition, 2016, p1-12Journal Article, 2016
Domínguez-Hüttinger, E., Christodoulides, P., Miyauchi, K., Irvine, A.D., Okada-Hatakeyama, M., Kubo, M., Tanaka, R.J., Mathematical modeling of atopic dermatitis reveals "double-switch" mechanisms underlying 4 common disease phenotypes, Journal of Allergy and Clinical Immunology, 2016Journal Article, 2016
Sakas, D.E., O"Connor, G., Singh, J., Dias, L., Eljamel, M.S., Mathew, B., Clements, B., Irvine, A., Gray, W.J., Byrnes, D.P., Bailey, I.C., Pathirana, N., Refsum, S., Bell, K.E., McKinstry, C.S., Callaghan, N., Crowley, M., Goggin, T., MacDermott, N., O"Driscoll, K.J., Neary, D., Pearson, N.A., Snowden, J.S., Brown, S., Vaughan, M., McMackin, D., Phillips, J., Burke, T., Murphy, S., Staunton, H., Cristea, R.L., Hourihane, M., Farrell, M.A., Morrison, P.J., Nevin, N.C., Collins, A.D., Gibson, M., Behan, W.M.H., Simpson, K.S., Cavanagh, H.M., Gow, J.W., Gillespie, J.S., Behan, P.O., Sklar, R.M., Brown, R.H., Gillian, A.M., O"Mahony, D., Breen, K.C., Hutchinson, J., Burke, T., Hutchinson, M., Droogan, A.G., Crockard, A.D., Hawkins, S.A., McNeill, T.A., Gutowski, N.J., Chirico, S., Pinkham, J.M., Smith, C., Akanu, D., Kaur, H., Strange, R.C., Halliwell, B., Murphy, R.P., Rogers, L., Weick, J., Estes, M., Elrington, G.M., Morris, C.S., Reffin, J.P., Tregear, S.J., Ripley, L.J., Rees, J.E., Irvine, A.D., O"Brien, D.P., Dias, P.S., Herity, N., Hawkins, S., McMenamin, J.B., Mirakhur, M., Allen, I.V., Bresnihan, B., Fitzsimmons, M., Sawhney, B., Patterson, V., Bailey, I.C., Byrnes, D., Watt, M., Lee, K.-C., Redmond, J.M.T., McKenna, M.J., Feingold, M., Ahmad, B.K., Watt, M., Cunningham, R.T., Winder, J., Lawson, J.A., Johnston, C.F., Buchanan, K.D., Dean, G., Elian, M., Gray, W.P., Ryder, D.Q., Buckley, T.F., Breathnach, K., Ooi, A., Farrell, M., Doherty, C., Hayes, F.J., Redmond, J.J.T., McKenna, M.M., Redmond, J.M.T., Farrell, M., Watt, M., Gibson, J.M., Patterson, V.H., Redmond, J.M.T., McKenna, M.J., Feingold, M., Ahmad, B.K., Moran, M., Burke, M., King, M.D., Moran, M., Burke, M., Hardiman, O., Reid, V., Dowd, J.O., Murphy, R., Rashad, E., Toland, J., Phillips, J.P., Staunton, H., Shu-Ming, P., Coughlin, A., Phillips, J.P., McCoy, D.M., Qureshi, A., Black, M.A., Grace, P.A., Bouchier-Hayes, D., Dwyer, R., Irish neurological association: Proceedings of 28th annual meeting, beaumont hospital, Dublin, 15th-16th may, 1992, Irish Journal of Medical Science, 162, (11), 1993, p474-484Journal Article, 1993
Fleury, O.M., McAleer, M.A., Feuillie, C., Formosa-Dague, C., Sansevere, E., Bennett, D.E., Towell, A.M., McLean, W.H.I., Kezic, S., Robinson, D.A., Fallon, P.G., Foster, T.J., Dufrêne, Y.F., Irvine, A.D., Geoghegan, J.A., Clumping factor B promotes adherence of Staphylococcus aureus to corneocytes in atopic dermatitis, Infection and Immunity, 85, (6), 2017, ppii: e00994-16Journal Article, 2017, TARA - Full Text
Murad, A., O'Regan, G., Watson, R., McDermott, M., O'Sullivan, M., Irvine, A.D., Erythema elevatum diutinum in a healthy child, Clinical and Experimental Dermatology, 42, (4), 2017, p434-436Journal Article, 2017
Lovgren, M.-L., McAleer, M.A., Irvine, A.D., Wilson, N.J., Tavadia, S., Schwartz, M.E., Cole, C., Sandilands, A., Smith, F.J.D., Zamiri, M., Mutations in desmoglein 1 cause diverse inherited palmoplantar keratoderma phenotypes: implications for genetic screening, British Journal of Dermatology, 176, (5), 2017, p1345-1350Journal Article, 2017
Eichenfield, L.F., Friedlander, S.F., Simpson, E.L., Irvine, A.D., Assessing the New and Emerging Treatments for Atopic Dermatitis, Seminars in cutaneous medicine and surgery, 35, (5), 2016, pS92-S96Journal Article, 2016
Irvine, A.D., Eichenfield, L.F., Friedlander, S.F., Simpson, E.L., Review of Critical Issues in the Pathogenesis of Atopic Dermatitis, Seminars in cutaneous medicine and surgery, 35, (5), 2016, pS89-S91Journal Article, 2016
Friedlander, S.F., Simpson, E.L., Irvine, A.D., Eichenfield, L.F., The Changing Paradigm of Atopic Dermatitis Therapy, Seminars in cutaneous medicine and surgery, 35, (5), 2016, pS97-S99Journal Article, 2016
Simpson, E.L., Irvine, A.D., Eichenfield, L.F., Friedlander, S.F., Update on Epidemiology, Diagnosis, and Disease Course of Atopic Dermatitis, Seminars in cutaneous medicine and surgery, 35, (5), 2016, pS84-S88Journal Article, 2016
Veronika Dvorakova, Grainne M. O'Regan, Alan D. Irvine, Methotrexate for Severe Childhood Atopic Dermatitis: Clinical Experience in a Tertiary Center, Pediatric Dermatology, 2017Journal Article, 2017
Veronika Dvorakova, David Rea, Grainne M. O'Regan, Alan D. Irvine, Generalized lymphatic anomaly successfully treated with long-term, low-dose sirolimus, Pediatric Dermatology, 2018Journal Article, 2018
M.A. McAleer, I. Jakasa, G. Hurault, P. Sarvari, W.H.I. McLean, R.J. Tanaka, S. Kezic, A.D. Irvine, Systemic and stratum corneum biomarkers of severity in infant atopic dermatitis include markers of innate and T helper cell-related immunity and angiogenesis, British Journal of Dermatology, 2018Journal Article, 2018
L.A.A. Gerbens, C.J. Apfelbacher, A.D. Irvine, S. Barbarot, R.J. de Booij, A.E. Boyce, M. Deleuran, L.F. Eichenfield, M.H. Hof, M.A. Middelkamp-Hup, A. Roberts, J. Schmitt, C. Vestergaard, D. Wall, S. Weidinger, P.R. Williamson, C. Flohr, P.I. Spuls, TREatment of ATopic eczema (TREAT) Registry Taskforce: an international Delphi exercise to identify a core set of domains and domain items for national atopic eczema photo- and systemic therapy registries, British Journal of Dermatology, 2018Journal Article, 2018
M.A. McAleer, I. Jakasa, N. Raj, C.P.F. O'Donnell, M.E. Lane, A.V. Rawlings, R. Voegeli, W.H.I. McLean, S. Kezic, A.D. Irvine, Early-life regional and temporal variation in filaggrin-derived natural moisturizing factor, filaggrin-processing enzyme activity, corneocyte phenotypes and plasmin activity: implications for atopic dermatitis, British Journal of Dermatology, 2018Journal Article, 2018
A.D. Irvine, A.P. Jones, P. Beattie, S. Baron, F. Browne, F. Ashoor, L. O'Neill, A. Rosala-Hallas, T. Sach, C. Spowart, L. Taams, C. Walker, M. Wan, N. Webb, P. Williamson, C. Flohr, A randomized controlled trial protocol assessing the effectiveness, safety and cost-effectiveness of methotrexate vs. ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema Trial (TREAT), British Journal of Dermatology, 2018Journal Article, 2018
Harkins, C.P., Holden, M.T.G., Irvine, A.D., Antimicrobial resistance in atopic dermatitis: Need for an urgent rethink, Annals of Allergy, Asthma and Immunology, 2019Journal Article, 2019
Eyerich, K., Brown, S.J., Perez White, B.E., Tanaka, R.J., Bissonette, R., Dhar, S., Bieber, T., Hijnen, D.J., Guttman-Yassky, E., Irvine, A., Thyssen, J.P., Vestergaard, C., Werfel, T., Wollenberg, A., Paller, A.S., Reynolds, N.J., Human and computational models of atopic dermatitis: A review and perspectives by an expert panel of the International Eczema Council, Journal of Allergy and Clinical Immunology, 143, (1), 2019, p36-45Journal Article, 2019
Clowry, J., Irvine, A.D., McLoughlin, R.M., Next-generation anti"Staphylococcus aureus vaccines: A potential new therapeutic option for atopic dermatitis?, Journal of Allergy and Clinical Immunology, 143, (1), 2019, p78-81Journal Article, 2019, DOI , TARA - Full Text
Davidson, W.F., Leung, D.Y.M., Beck, L.A., Berin, C.M., Boguniewicz, M., Busse, W.W., Chatila, T.A., Geha, R.S., Gern, J.E., Guttman-Yassky, E., Irvine, A.D., Kim, B.S., Kong, H.H., Lack, G., Nadeau, K.C., Schwaninger, J., Simpson, A., Simpson, E.L., Spergel, J.M., Togias, A., Wahn, U., Wood, R.A., Woodfolk, J.A., Ziegler, S.F., Plaut, M., Report from the National Institute of Allergy and Infectious Diseases workshop on "Atopic dermatitis and the atopic march: Mechanisms and interventions", Journal of Allergy and Clinical Immunology, 2019Journal Article, 2019
Paller, A.S., Spergel, J.M., Mina-Osorio, P., Irvine, A.D., The atopic march and atopic multimorbidity: Many trajectories, many pathways, Journal of Allergy and Clinical Immunology, 143, (1), 2019, p46-55Journal Article, 2019
Paller, A.S., Kong, H.H., Seed, P., Naik, S., Scharschmidt, T.C., Gallo, R.L., Luger, T., Irvine, A.D., The microbiome in patients with atopic dermatitis, Journal of Allergy and Clinical Immunology, 143, (1), 2019, p26-35Journal Article, 2019
McCarthy, E.K., Murray, D.M., Malvisi, L., Kenny, L.C., O'B Hourihane, J., Irvine, A.D., Kiely, M.E., Antenatal Vitamin D Status Is Not Associated with Standard Neurodevelopmental Assessments at Age 5 Years in a Well-Characterized Prospective Maternal-Infant Cohort, Journal of Nutrition, 148, (10), 2018, p1580-1586Journal Article, 2018
Hennessy, Á., Hourihane, J.O.B., Malvisi, L., Irvine, A.D., Kenny, L.C., Murray, D.M., Kiely, M.E., Antenatal vitamin D exposure and childhood eczema, food allergy, asthma and allergic rhinitis at 2 and 5 years of age in the atopic disease-specific Cork BASELINE Birth Cohort Study, Allergy: European Journal of Allergy and Clinical Immunology, 73, (11), 2018, p2182-2191Journal Article, 2018
Lynch, S.A., Crushell, E., Lambert, D.M., Byrne, N., Gorman, K., King, M.D., Green, A., O'Sullivan, S., Browne, F., Hughes, J., Knerr, I., Monavari, A.A., Cotter, M., McConnell, V.P.M., Kerr, B., Jones, S.A., Keenan, C., Murphy, N., Cody, D., Ennis, S., Turner, J., Irvine, A.D., Casey, J., Catalogue of inherited disorders found among the Irish Traveller population, Journal of Medical Genetics, 55, (4), 2018, p233-239Journal Article, 2018
Twelves, S., Mostafa, A., Dand, N., Burri, E., Farkas, K., Wilson, R., Cooper, H.L., Irvine, A.D., Oon, H.H., Kingo, K., Köks, S., Mrowietz, U., Puig, L., Reynolds, N., Tan, E.S.-T., Tanew, A., Torz, K., Trattner, H., Valentine, M., Wahie, S., Warren, R.B., Wright, A., Bata-Csörg", Z., Szell, M., Griffiths, C.E.M., Burden, A.D., Choon, S.-E., Smith, C.H., Barker, J.N., Navarini, A.A., Capon, F., Clinical and genetic differences between pustular psoriasis subtypes, Journal of Allergy and Clinical Immunology, 2018Journal Article, 2018
Hawkes, C.P., Murray, D.M., Kenny, L.C., Kiely, M., O'B Hourihane, J., Irvine, A.D., Wu, Z., Argon, Y., Reitz, R.E., McPhaul, M.J., Grimberg, A., Correlation of Insulin-Like Growth Factor-I and -II Concentrations at Birth Measured by Mass Spectrometry and Growth from Birth to Two Months, Hormone Research in Paediatrics, 89, (2), 2018, p122-131Journal Article, 2018
McCarthy, E.K., ní Chaoimh, C., Kenny, L.C., Hourihane, J.O.B., Irvine, A.D., Murray, D.M., Kiely, M.E., Iron status, body size, and growth in the first 2 years of life, Maternal and Child Nutrition, 14, (1), 2018Journal Article, 2018
Simpson, E.L., Reynolds, N.J., Flohr, C., Paller, A.S., Silverberg, J.I., Cork, M.J., Guttman-Yassky, E., Irvine, A.D., Response to "Comment on: `When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council"", Journal of the American Academy of Dermatology, 79, (2), 2018, pe25-e26Journal Article, 2018
Paller, A.S., Czarnowicki, T., Renert-Yuval, Y., Holland, K., Huynh, T., Sadlier, M., McAleer, M.A., Tran, G., Geddes, G.C., Irvine, A.D., Guttman-Yassky, E., The spectrum of manifestations in desmoplakin gene (DSP) spectrin repeat 6 domain mutations: Immunophenotyping and response to ustekinumab, Journal of the American Academy of Dermatology, 78, (3), 2018, p498-505.e2Journal Article, 2018
Drucker, A.M., Eyerich, K., de Bruin-Weller, M.S., Thyssen, J.P., Spuls, P.I., Irvine, A.D., Girolomoni, G., Dhar, S., Flohr, C., Murrell, D.F., Paller, A.S., Guttman-Yassky, E., Use of systemic corticosteroids for atopic dermatitis: International Eczema Council consensus statement, British Journal of Dermatology, 178, (3), 2018, p768-775Journal Article, 2018
Hennessy, Á., Ní Chaoimh, C., McCarthy, E.K., Kingston, C., Irvine, A.D., Hourihane, J.O., Kenny, L.C., Murray, D.M., Kiely, M., Variation in iodine food composition data has a major impact on estimates of iodine intake in young children, European Journal of Clinical Nutrition, 72, (3), 2018, p410-419Journal Article, 2018
McCarthy, E.K., Kenny, L.C., Hourihane, J.O., Irvine, A.D., Murray, D.M., Kiely, M.E., Impact of maternal, antenatal and birth-associated factors on iron stores at birth: Data from a prospective maternal-infant birth cohort, European Journal of Clinical Nutrition, 71, (6), 2017, p782-787Journal Article, 2017
McCarthy, E.K., Kiely, M.E., Hannon, G., Ahearne, C., Kenny, L.C., Hourihane, J.O., Irvine, A.D., Murray, D.M., Microcytosis is associated with low cognitive outcomes in healthy 2-year-olds in a high-resource setting, British Journal of Nutrition, 118, (5), 2017, p360-367Journal Article, 2017
Spuls, P.I., Gerbens, L.A.A., Apfelbacher, C.J., Wall, D., Arents, B.W.M., Barbarot, S., Roberts, A., Deleuran, M., Middelkamp-Hup, M.A., Vestergaard, C., Weidinger, S., Schmitt, J., Irvine, A.D., Flohr, C., The International TREatment of ATopic Eczema (TREAT) Registry Taskforce: An Initiative to Harmonize Data Collection across National Atopic Eczema Photo- and Systemic Therapy Registries, Journal of Investigative Dermatology, 137, (9), 2017, p2014-2016Journal Article, 2017
Simpson, E.L., Bruin-Weller, M., Flohr, C., Ardern-Jones, M.R., Barbarot, S., Deleuran, M., Bieber, T., Vestergaard, C., Brown, S.J., Cork, M.J., Drucker, A.M., Eichenfield, L.F., Foelster-Holst, R., Guttman-Yassky, E., Nosbaum, A., Reynolds, N.J., Silverberg, J.I., Schmitt, J., Seyger, M.M.B., Spuls, P.I., Stalder, J.-F., Su, J.C., Takaoka, R., Traidl-Hoffmann, C., Thyssen, J.P., van der Schaft, J., Wollenberg, A., Irvine, A.D., Paller, A.S., When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council, Journal of the American Academy of Dermatology, 77, (4), 2017, p623-633Journal Article, 2017
Towell AM, Feuillie C, Vitry P, Da Costa TM, Mathelié-Guinlet M, Kezic S, Fleury OM, McAleer MA, Dufrêne YF, Irvine AD, Geoghegan JA, Staphylococcus aureus binds to the N-terminal region of corneodesmosin to adhere to the stratum corneum in atopic dermatitis, Proceedings of the National Academy of Sciences of the United States of America, 118, (1), 2021, pe2014444118Journal Article, 2021, URL
Drislane, C., Irvine, A.D., The role of filaggrin in atopic dermatitis and allergic disease, Annals of Allergy, Asthma and Immunology, 124, (1), 2020, p36-43Journal Article, 2020
H. Blakeway, V. Van"de"Velde, V.B. Allen, G. Kravvas, L. Palla, M.J. Page, C. Flohr, R.B. Weller, A.D. Irvine, T. McPherson, A. Roberts, H.C. Williams, N. Reynolds, S.J. Brown, L. Paternoster, S.M. Langan, What is the evidence for interactions between filaggrin null mutations and environmental exposures in the aetiology of atopic dermatitis? A systematic review, British Journal of Dermatology, 2020Journal Article, 2020
J. Nousbeck, M.A. McAleer, G. Hurault, E. Kenny, K. Harte, S. Kezic, R.J. Tanaka, A.D. Irvine, MicroRNA analysis of childhood atopic dermatitis reveals a role for miR"451a, British Journal of Dermatology, 2020Journal Article, 2020
L. Cunningham, V. Dvorakova, F. Browne, A.D. Irvine, High dose Bilastine for the treatment of Bascule Syndrome, Clinical and Experimental Dermatology, 2020Journal Article, 2020
Marek Haftek, Maeve A McAleer, Ivone Jakasa, WH Irwin McLean, Sanja Kezic, Alan D. Irvine, Changes in nano-mechanical properties of human epidermal cornified cells in children with atopic dermatitis, Wellcome Open Research, 5, 2020, p97Journal Article, 2020
Doreen Siegels, Annice Heratizadeh, Susanne Abraham, Jonas Binnmyr, Knut Brockow, Alan D. Irvine, Susanne Halken, Charlotte G Mortz, Carsten Flohr, Peter Schmid"Grendelmeier, Lauri"Ann Poel, Antonella Muraro, Stephan Weidinger, Thomas Werfel, Jochen Schmitt, Systemic treatments in the management of atopic dermatitis: A systematic review and meta"analysis, Allergy, 2020Journal Article, 2020
F.M. Vermeulen, L.A.A. Gerbens, J. Schmitt, M. Deleuran, A.D. Irvine, K. Logan, W. Ouwerkerk, C. Vestergaard, C. Flohr, P.I. Spuls, The European TREatment of ATopic eczema (TREAT) Registry Taskforce survey: prescribing practices in Europe for phototherapy and systemic therapy in adult patients with moderate"to"severe atopic eczema*, British Journal of Dermatology, 2020Journal Article, 2020
M.A. McAleer, I. Jakasa, N. Stefanovic, W.H.I. McLean, S. Kezic, A.D. Irvine, Topical Corticosteroids Normalize both Skin and Systemic Inflammatory Markers in Infant Atopic Dermatitis, British Journal of Dermatology, 2020Journal Article, 2020
Nicholas Stefanovic, Carsten Flohr, Alan D. Irvine, The exposome in atopic dermatitis, Allergy, 2019Journal Article, 2019
E. Chasseuil, J.A. McGrath, A. Seo, X. Balguerie, N. Bodak, H. Chasseuil, M. Denis"Musquer, A. Goldenberg, R. Goussot, A.D. Irvine, N.P. Khumalo, M.C. King, S. Küry, D. Lipsker, S. Mallet, B.M. Mayosi, A. Nanda, E. Puzenat, E. Salort"Campana, R. Sidbury, A. Shimamura, S. Bézieau, S. Mercier, S. Barbarot, Dermatological manifestations of hereditary fibrosing poikiloderma with tendon contractures, myopathy and pulmonary fibrosis ( POIKTMP ): a case series of 28 patients, British Journal of Dermatology, 2019Journal Article, 2019
A.D. Irvine, P. Mina"Osorio, Disease trajectories in childhood atopic dermatitis: an update and practitioner's guide, British Journal of Dermatology, 2019Journal Article, 2019
H. Alexander, A.S. Paller, C. Traidl"Hoffmann, L.A. Beck, A. De Benedetto, S. Dhar, G. Girolomoni, A.D. Irvine, P. Spuls, J. Su, J.P. Thyssen, C. Vestergaard, T. Werfel, A. Wollenberg, M. Deleuran, C. Flohr, The role of bacterial skin infections in atopic dermatitis: expert statement and review from the International Eczema Council Skin Infection Group, British Journal of Dermatology, 2019Journal Article, 2019
F.M. Vermeulen, L.A.A. Gerbens, A.L. Bosma, C.J. Apfelbacher, A.D. Irvine, B.W.M. Arents, S. Barbarot, M. Deleuran, L.F. Eichenfield, A. Manca, J. Schmitt, C. Vestergaard, D. Wall, S. Weidinger, M.A. Middelkamp"Hup, P.I. Spuls, C. Flohr, TRE atment of AT opic eczema ( TREAT ) Registry Taskforce: consensus on how and when to measure the core dataset for atopic eczema treatment research registries, British Journal of Dermatology, 181, (3), 2019, p492--504Journal Article, 2019
Ballin, N., Hotz, A., Bourrat, E., Küsel, J., Oji, V., Bouadjar, B., Brognoli, D., Hickman, G., Heinz, L., Vabres, P., Marrakchi, S., Leclerc-Mercier, S., Irvine, A., Tadini, G., Hamm, H., Has, C., Blume-Peytavi, U., Mitter, D., Reitenbach, M., Hausser, I., Zimmer, A.D., Alter, S., Fischer, J., Genetical, clinical, and functional analysis of a large international cohort of patients with autosomal recessive congenital ichthyosis due to mutations in NIPAL4, Human Mutation, 40, (12), 2019, p2318-2333Journal Article, 2019
Leshem, Y.A., Bissonnette, R., Paul, C., Silverberg, J.I., Irvine, A.D., Paller, A.S., Cork, M.J., Guttman-Yassky, E., Optimization of placebo use in clinical trials with systemic treatments for atopic dermatitis: an International Eczema Council survey-based position statement, Journal of the European Academy of Dermatology and Venereology, 33, (5), 2019, p807-815Journal Article, 2019
Revencu, N., Fastre, E., Ravoet, M., Helaers, R., Brouillard, P., Bisdorff-Bresson, A., Chung, C.W.T., Gerard, M., Dvorakova, V., Irvine, A.D., Boon, L.M., Vikkula, M., RASA1 mosaic mutations in patients with capillary malformation-arteriovenous malformation, Journal of Medical Genetics, 2019Journal Article, 2019
Bosma, A.L., Spuls, P.I., Garcia-Doval, I., Naldi, L., Prieto-Merino, D., Tesch, F., Apfelbacher, C.J., Arents, B.W.M., Barbarot, S., Baselga, E., Deleuran, M., Eichenfield, L.F., Gerbens, L.A.A., Irvine, A.D., Manca, A., Mendes-Bastos, P., Middelkamp-Hup, M.A., Roberts, A., Seneschal, J., Svensson, Å., Thyssen, J.P., Torres, T., Vermeulen, F.M., Vestergaard, C., von Kobyletzki, L.B., Wall, D., Weidinger, S., Schmitt, J., Flohr, C., TREatment of ATopic eczema (TREAT) Registry Taskforce: protocol for a European safety study of dupilumab and other systemic therapies in patients with atopic eczema, British Journal of Dermatology, 2019Journal Article, 2019
Hawkes, C.P., Grimberg, A., Kenny, L.C., Kiely, M., Hourihane, J.O.B., Irvine, A.D., McPhaul, M.J., Caulfield, M.P., Zemel, B.S., Murray, D.M., The relationship between IGF-I and -II concentrations and body composition at birth and over the first 2 months, Pediatric Research, 85, (5), 2019, p687-692Journal Article, 2019
Doherty AM, Colleran GC, Durcan L, Irvine AD, Barrett E, A pilot study of burnout and long covid in senior specialist doctors., Irish journal of medical science, 2021Journal Article, 2021
Takuya Miyano, Alan D Irvine, Reiko J Tanaka, A mathematical model to identify optimal combinations of drug targets for dupilumab poor responders in atopic dermatitis, 2021Journal Article, 2021
Jennifer M. E. Boggs, Alan D. Irvine, PLACK syndrome resulting from a novel homozygous variant in CAST, Pediatric Dermatology, 2021Journal Article, 2021
Karina Forde, Nicoletta Resta, Carlotta Ranieri, David Rea, Olga Kubassova, Mark Hinton, Alan D Irvine, Veronika Dvorakova, Clinical Experience with the AKT1 Inhibitor Miransertib in two Children with PIK3CA-related overgrowth syndrome, 2020Journal Article, 2020
Bradshaw, Lucy E., Haines, Rachel H., Thomas, Kim S., Chalmers, Joanne R., Irvine, Alan D., Williams, Hywel C., Brown, Sara J., Clinical examination for hyperlinear palms to determine filaggrin genotype: A diagnostic test accuracy study, Clinical & Experimental Allergy, 51, (11), 2021, p1421-1428Journal Article, 2021, DOI
Freeman, Esther E., Chamberlin, Grace C., McMahon, Devon E., Hruza, George J., Wall, Dmitri, Meah, Nekma, Sinclair, Rodney, Balogh, Esther A., Feldman, Steven R., Lowes, Michelle A., Marzano, Angelo V., Naik, Haley B., Castelo-Soccio, Leslie, Lara-Corrales, Irene, Cordoro, Kelly M., Mahil, Satveer K., Griffiths, Christopher E.M., Smith, Catherine H., Irvine, Alan D., Spuls, Phyllis I., Flohr, Carsten, French, Lars E., Dermatology COVID-19 Registries, Dermatologic Clinics, 39, (4), 2021, p575-585Journal Article, 2021, DOI
Holm, Annegret, te Loo, Maroeska, Schultze Kool, Leo, Salminen, Päivi, Celis, Veronica, Baselga, Eulalia, Duignan, Sophie, Dvorakova, Veronika, Irvine, Alan D., Boon, Laurence M., Vikkula, Miikka, Ghaffarpour, Nader, Niemeyer, Charlotte M., Rössler, Jochen, Kapp, Friedrich G., Efficacy of Sirolimus in Patients Requiring Tracheostomy for Life-Threatening Lymphatic Malformation of the Head and Neck: A Report From the European Reference Network, Frontiers in Pediatrics, 9, 2021Journal Article, 2021, DOI
Stefanovic, Nicholas, Irvine, Alan D., Flohr, Carsten, The Role of the Environment and Exposome in Atopic Dermatitis, Current Treatment Options in Allergy, 8, (3), 2021, p222-241Journal Article, 2021, DOI
Mulick, A.R., Mansfield, K.E., Silverwood, R.J., Budu"Aggrey, A., Roberts, A., Custovic, A., Pearce, N., Irvine, A.D., Smeeth, L., Abuabara, K., Langan, S.M., Four childhood atopic dermatitis subtypes identified from trajectory and severity of disease and internally validated in a large UK birth cohort, British Journal of Dermatology, 185, (3), 2021, p526-536Journal Article, 2021, DOI
Xing, Chao, Kanchwala, Mohammed, Rios, Jonathan J., Hyatt, Tommy, Wang, Richard C., Tran, An, Dougherty, Irene, Tovar"Garza, Andrea, Purnadi, Christy, Kumar, Monique G., Berk, David, Shinawi, Marwan, Irvine, Alan D., Toledo"Bahena, Mirna, Agim, Nnenna G., Glass, Donald A., Biallelic variants in RNU12 cause CDAGS syndrome, Human Mutation, 42, (8), 2021, p1042-1052Journal Article, 2021, DOI
Deleuran, M, Marcoux, D, Bruin-Weller, M, Irvine, A, Baselga, E, Ahn, K, Castro, A, Bansal, A, Chao, J, Bégo-Le-Bagousse, G, Rossi, A, Dupilumab Provides Significant Clinical Benefit in a Phase 3 Trial in Adolescents with Uncontrolled Atopic Dermatitis Irrespective of Prior Systemic Immunosuppressant Use, Acta Dermato Venereologica, 101, (7), 2021, padv00504Journal Article, 2021, DOI
Luger, T., Paller, A.S., Irvine, A.D., Sidbury, R., Eichenfield, L.F., Werfel, T., Bieber, T., Topical therapy of atopic dermatitis with a focus on pimecrolimus, Journal of the European Academy of Dermatology and Venereology, 35, (7), 2021, p1505-1518Journal Article, 2021, DOI
Abuabara, K., Nicholls, S.G., Langan, S.M., Guttman"Yassky, E., Reynolds, N.J., Paller, A.S., Brown, S.J., , , Priority research questions in atopic dermatitis: an International Eczema Council eDelphi consensus, British Journal of Dermatology, 185, (1), 2021, p203-205Journal Article, 2021, DOI
Guttman-Yassky, Emma, Teixeira, Henrique D, Simpson, Eric L, Papp, Kim A, Pangan, Aileen L, Blauvelt, Andrew, Thaçi, Diamant, Chu, Chia-Yu, Hong, H Chih-ho, Katoh, Norito, Paller, Amy S, Calimlim, Brian, Gu, Yihua, Hu, Xiaofei, Liu, Meng, Yang, Yang, Liu, John, Tenorio, Allan R, Chu, Alvina D, Irvine, Alan D, Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double-blind, randomised controlled phase 3 trials, The Lancet, 397, (10290), 2021, p2151-2168Journal Article, 2021, DOI
Meah, Nekma, Wall, Dmitri, York, Katherine, Bhoyrul, Bevin, Bokhari, Laita, Asz-Sigall, Daniel, Bergfeld, Wilma F., Betz, Regina C., Blume-Peytavi, Ulrike, Callender, Valerie, Chitreddy, Vijaya, Combalia, Andrea, Cotsarelis, George, Craiglow, Brittany, Donovan, Jeff, Eisman, Samantha, Farrant, Paul, Green, Jack, Grimalt, Ramon, Harries, Matthew, Hordinsky, Maria, Irvine, Alan D., Itami, Satoshi, Jolliffe, Victoria, King, Brett, Lee, Won-Soo, McMichael, Amy, Messenger, Andrew, Mirmirani, Paradi, Olsen, Elise, Orlow, Seth J., Piraccini, Bianca Maria, Rakowska, Adriana, Reygagne, Pascal, Roberts, Janet L., Rudnicka, Lidia, Shapiro, Jerry, Sharma, Pooja, Tosti, Antonella, Vogt, Annika, Wade, Martin, Yip, Leona, Zlotogorski, Abraham, Sinclair, Rodney D., The Alopecia Areata Consensus of Experts (ACE) study part II: Results of an international expert opinion on diagnosis and laboratory evaluation for alopecia areata, Journal of the American Academy of Dermatology, 84, (6), 2021, p1594-1601Journal Article, 2021, DOI
Wall, Dmitri, Alhusayen, Raed, Arents, Bernd, Apfelbacher, Christian, Balogh, Esther A., Bokhari, Laita, Bloem, Manja, Bosma, Angela L., Burton, Tim, Castelo-Soccio, Leslie, Fagan, Nicole, Feldman, Steven R., Fletcher, Godfrey, Flohr, Carsten, Freeman, Esther, French, Lars E., Griffiths, Christopher E.M., Hruza, George J., Ingram, John R., Kappelman, Michael D., Lara-Corrales, Irene, Lim, Henry W., Meah, Nekma, McMahon, Devon E., Mahil, Satveer K., McNicoll, Ian, Musters, Annelie, Naik, Haley B., Sinclair, Rodney, Smith, Catherine H., Spuls, Phyllis, Tobin, Desmond J., York, Katherine, Irvine, Alan D., Learning from disease registries during a pandemic: Moving toward an international federation of patient registries, Clinics in Dermatology, 39, (3), 2021, p467-478Journal Article, 2021, DOI
Onoufriadis, A., Cabezas, A., Ng, J.C.F., Canales, J., Costas, M.J., Ribeiro, J.M., Rodrigues, J.R., McAleer, M.A., Castelo"Soccio, L., Simpson, M.A., Fraternali, F., Irvine, A.D., Cameselle, J.C., McGrath, J.A., Autosomal recessive hypotrichosis with loose anagen hairs associated with TKFC mutations*, British Journal of Dermatology, 184, (5), 2021, p935-943Journal Article, 2021, DOI
McCarthy, Elaine K, Murray, Deirdre M, Hourihane, Jonathan O"B, Kenny, Louise C, Irvine, Alan D, Kiely, Mairead E, Behavioral consequences at 5 y of neonatal iron deficiency in a low-risk maternal"infant cohort, The American Journal of Clinical Nutrition, 113, (4), 2021, p1032-1041Journal Article, 2021, DOI
Wall, Dmitri, Meah, Nekma, York, Katherine, Bhoyrul, Bevin, Bokhari, Laita, Abraham, Leonardo Spagnol, Adams, Roisín, Bergfeld, Wilma, Betz, Regina C., Blume-Peytavi, Ulrike, Callender, Valerie, Campbell, Chel, Chambers, Jen, Chen, Gang, Chitreddy, Vijaya, Cotsarelis, George, Craiglow, Brittany, Dhurat, Rachita, Dlova, Ncoza, Donovan, Jeff, Duque-Estrada, Bruna, Eisman, Samantha, Ellison, Abby, Farrant, Paul, Barberá, Juan Ferrando, Gadzhigoroeva, Aida, Grimalt, Ramon, Harries, Matthew, Hordinsky, Maria, Irvine, Alan D., Jolliffe, Victoria, Jones, Leslie, King, Brett, Lee, Won-Soo, Lortkipanidze, Nino, McMichael, Amy, Messenger, Andrew, Mirmirani, Paradi, Olsen, Elise, Orlow, Seth J., Ovcharenko, Yuliya, Piraccini, Bianca Maria, Pirmez, Rodrigo, Rakowska, Adriana, Reygagne, Pascal, Riley, Melissa, Rudnicka, Lidia, Saceda Corralo, David, Shapiro, Jerry, Sharma, Pooja, Silyuk, Tatiana, Kaiumov, Spartak, Tobin, Desmond J., Tosti, Antonella, Vañó-Galván, Sergio, Vogt, Annika, Wade, Martin, Yip, Leona, Zlotogorski, Abraham, Zhou, Cheng, Sinclair, Rodney, A Global eDelphi Exercise to Identify Core Domains and Domain Items for the Development of a Global Registry of Alopecia Areata Disease Severity and Treatment Safety (GRASS), JAMA Dermatology, 157, (4), 2021, p439Journal Article, 2021, DOI
Silverberg, Jonathan I., Simpson, Eric L., Armstrong, April W., de Bruin-Weller, Marjolein S., Irvine, Alan D., Reich, Kristian, Expert Perspectives on Key Parameters that Impact Interpretation of Randomized Clinical Trials in Moderate-to-Severe Atopic Dermatitis, American Journal of Clinical Dermatology, 2021Journal Article, 2021, DOI
Delles, C, Dayan, C M, Dominiczak, A F, Donnelly, S C, Irvine, A D, Announcing the first AoP webinar: `Can evidence-based medicine survive in a pandemic?", QJM: An International Journal of Medicine, 114, (1), 2021, p11-12Journal Article, 2021, DOI
Hotz, Alrun, Kopp, Julia, Bourrat, Emmanuelle, Oji, Vinzenz, Komlosi, Katalin, Giehl, Kathrin, Bouadjar, Bakar, Bygum, Anette, Tantcheva-Poor, Iliana, Hellström Pigg, Maritta, Has, Cristina, Yang, Zhou, Irvine, Alan D., Betz, Regina C., Zambruno, Giovanna, Tadini, Gianluca, Süßmuth, Kira, Gruber, Robert, Schmuth, Matthias, Mazereeuw-Hautier, Juliette, Jonca, Natalie, Guez, Sophie, Brena, Michela, Hernandez-Martin, Angela, van den Akker, Peter, Bolling, Maria C., Hannula-Jouppi, Katariina, Zimmer, Andreas D., Alter, Svenja, Vahlquist, Anders, Fischer, Judith, Meta-Analysis of Mutations in ALOX12B or ALOXE3 Identified in a Large Cohort of 224 Patients, Genes, 12, (1), 2021, p80Journal Article, 2021, DOI
Fagan, Nicole, Meah, Nekma, York, Katherine, Bokhari, Laita, Fletcher, Godfrey, Chen, Gang, Tobin, Desmond J., Messenger, Andrew, Irvine, Alan D., Sinclair, Rodney, Wall, Dmitri, Shedding light on therapeutics in alopecia and their relevance to COVID-19, Clinics in Dermatology, 39, (1), 2021, p76-83Journal Article, 2021, DOI
Cathal O'Connor, Vicki Livingstone, Jonathan O'. B. Hourihane, Alan D. Irvine, Geraldine Boylan, Deirdre Murray, Parental atopy and risk of atopic dermatitis in the first two years of life in the BASELINE birth cohort study, Pediatric Dermatology, 2022Journal Article, 2022
Takuya Miyano, Alan D Irvine, Reiko J Tanaka, Model-based meta-analysis to optimise S. aureus-targeted therapies for atopic dermatitis, 2021Journal Article, 2021, DOI
Walsh, Carleen, Leavey, Gerard, Mc Laughlin, Marian, Paller, Amy S, Irvine, Alan D, Browne, Fiona, Mellerio, Jemima E, Bewley, Anthony, Novel mixed-method, inclusive protocol involving global key stakeholders, including carers as experts, to co-develop relevant Caregiver-Reported Outcome Domains (CRODs) in skin disease, BMJ Open, 13, (1), 2023, pe068893Journal Article, 2023, DOI
Nousbeck, Janna, McAleer, Maeve A., Irvine, Alan D., Peripheral Blood Gene Expression Profile of Infants with Atopic Dermatitis, JID Innovations, 3, (2), 2023, p100165Journal Article, 2023, DOI
Cox F, Bigley V, Irvine A, Leahy R, Conlon N., PAMI Syndrome: Two Cases of an Autoinflammatory Disease with an ALPS-Like Phenotype., Journal of clinical immunology, 42, (5), 2022, p955-958Journal Article, 2022, DOI
Lucy E. Bradshaw, Rachel H. Haines, Kim S. Thomas, Joanne R. Chalmers, Alan D. Irvine, Hywel C. Williams, Sara J. Brown, Clinical examination for hyperlinear palms to determine filaggrin genotype: A diagnostic test accuracy study, Clinical & Experimental Allergy, 2021Journal Article, 2021, DOI
A.R. Mulick, K.E. Mansfield, R.J. Silverwood, A. Budu"Aggrey, A. Roberts, A. Custovic, N. Pearce, A.D. Irvine, L. Smeeth, K. Abuabara, S.M. Langan, Four childhood atopic dermatitis subtypes identified from trajectory and severity of disease and internally validated in a large UK birth cohort, British Journal of Dermatology, 185, (3), 2021, p526--536Journal Article, 2021, DOI
Irvine, A.D., Hoeger, P.H., Yan, A.C., Preface to the third edition, Harper's Textbook of Pediatric Dermatology: Third Edition, 1, 2011Journal Article, 2011
Fagan, N., Browne, F., Dvorakova, V., Carroll, A., Irvine, A.D., Getting it right the first time: an Irish paediatric dermatology perspective from a national care centre, Clinical and Experimental Dermatology, 49, (1), 2024, p61-64Journal Article, 2024
Mysler, E., Burmester, G.R., Saffore, C.D., Liu, J., Wegrzyn, L., Yang, C., Betts, K.A., Wang, Y., Irvine, A.D., Panaccione, R., Safety of Upadacitinib in Immune-Mediated Inflammatory Diseases: Systematic Literature Review of Indirect and Direct Treatment Comparisons of Randomized Controlled Trials, Advances in Therapy, 2024Journal Article, 2024
Renert-Yuval, Y., Del Duca, E., Arents, B., Bissonnette, R., Drucker, A.M., Flohr, C., Guttman-Yassky, E., Hijnen, D., Kabashima, K., Leshem, Y.A., Paller, A.S., Silverberg, J.I., Simpson, E.L., Spuls, P., Vestergaard, C., Wollenberg, A., Irvine, A.D., Thyssen, J.P., Treat-to-target in dermatology: A scoping review and International Eczema Council survey on the approach in atopic dermatitis, Journal of the European Academy of Dermatology and Venereology, 38, (1), 2024, p42-51Journal Article, 2024
Zuberbier, T., Abdul Latiff, A., Aggelidis, X., Augustin, M., Balan, R.-G., Bangert, C., Beck, L., Bieber, T., Bernstein, J.A., Bertolin Colilla, M., Berardi, A., Bedbrook, A., Bindslev-Jensen, C., Bousquet, J., de Bruin-Weller, M., Bruscky, D., Buyuktiryaki, B., Canonica, G.W., Castro, C., Chanturidze, N., Chong-Neto, H.J., Chu, C.-Y., Chularojanamontri, L., Cork, M., Criado, R.F.J., Barredo, L.C., Custovic, A., Darsow, U., Emurlai, A., de Pablo, A., Del Giacco, S., Girolomoni, G., Deleva Jovanova, T., Deleuran, M., Douladiris, N., Duarte, B., Dubakiene, R., Eller, E., Engel-Yeger, B., Ensina, L.F., Filho, N.R., Flohr, C., Fomina, D., Francuzik, W., Galimberti, M.L., Giménez-Arnau, A.M., Godse, K., Mortz, C.G., Gotua, M., Hide, M., Hoetzenecker, W., Hunzelmann, N., Irvine, A., Jack, C., Kanavarou, I., Katoh, N., Kinaciyan, T., Kocatürk, E., Kulthanan, K., Lapeere, H., Lau, S., Machado Forti Nastri, M., Makris, M., Mansour, E., Marsland, A., Morelo Rocha Felix, M., Moschione Castro, A.P., Nettis, E., Nicolas, J.F., Nosbaum, A., Odemyr, M., Papapostolou, N., Parisi, C.A.S., Paudel, S., Peter, J., Pokharel, P., Puig, L., Quint, T., Ramon, G.D., Regateiro, F., Ricci, G., Rosario, C., Sackesen, C., Schmid-Grendelmeier, P., Serra-Baldrich, E., Siemens, K., Smith, C., Staubach, P., Stevanovic, K., Su-Kücük, Ö., Sussman, G., Tavecchio, S., Teovska Mitrevska, N., Thaci, D., Toubi, E., Traidl-Hoffmann, C., Treudler, R., Vadasz, Z., van Hofman, I., Ventura, M.T., Wang, Z., Werfel, T., Wollenberg, A., Yang, A., Weng Yew, Y., Zhao, Z., Zwiener, R., Worm, M., A concept for integrated care pathways for atopic dermatitis"A GA2LEN ADCARE initiative, Clinical and Translational Allergy, 13, (9), 2023Journal Article, 2023
Duggan, C., Irvine, A.D., O"B Hourihane, J., Kiely, M.E., Murray, D.M., ASQ-3 and BSID-III"s concurrent validity and predictive ability of cognitive outcome at 5 years, Pediatric Research, 94, (4), 2023, p1465-1471Journal Article, 2023
Canaud, G., Lopez Gutierrez, J.C., Irvine, A.D., Vabres, P., Hansford, J.R., Ankrah, N., Branle, F., Papadimitriou, A., Ridolfi, A., O'Connell, P., Turner, S., Adams, D.M., Alpelisib for treatment of patients with PIK3CA-related overgrowth spectrum (PROS), Genetics in Medicine, 25, (12), 2023Journal Article, 2023
Bosma, A.L., Ouwerkerk, W., Heidema, M.J., Prieto-Merino, D., Ardern-Jones, M.R., Beattie, P., Brown, S.J., Ingram, J.R., Irvine, A.D., Ogg, G., Patel, P., Reynolds, N.J., Hearn, R.M.R., Wan, M., Warren, R.B., Woolf, R.T., Hyseni, A.M., Gerbens, L.A.A., Spuls, P.I., Flohr, C., Middelkamp-Hup, M.A., Comparison of real-world treatment outcomes of systemic immunomodulating therapy in atopic dermatitis patients with dark and light skin types, JAAD International, 10, 2023, p14-24Journal Article, 2023
Bieber, T., Feist, E., Irvine, A.D., Harigai, M., Haladyj, E., Ball, S., Deberdt, W., Issa, M., Grond, S., Taylor, P.C., Correction to: A Review of Safety Outcomes from Clinical Trials of Baricitinib in Rheumatology, Dermatology and COVID-19 (Advances in Therapy, (2022), 39, 11, (4910-4960), 10.1007/s12325-022-02281-4), Advances in Therapy, 40, (9), 2023, p4114-4115Journal Article, 2023
Paller, A.S., Silverberg, J.I., Cork, M.J., Guttman-Yassky, E., Lockshin, B., Irvine, A.D., Kim, M.B., Kabashima, K., Chen, Z., Lu, Y., Bansal, A., Rossi, A.B., Shabbir, A., Efficacy and Safety of Dupilumab in Patients with Erythrodermic Atopic Dermatitis: A Post Hoc Analysis of 6 Randomized Clinical Trials, JAMA Dermatology, 159, (3), 2023, p255-266Journal Article, 2023
Paller, A.S., Ladizinski, B., Mendes-Bastos, P., Siegfried, E., Soong, W., Prajapati, V.H., Lio, P., Thyssen, J.P., Simpson, E.L., Platt, A.M., Raymundo, E.M., Liu, J., Calimlim, B.M., Huang, X., Gu, Y., Hu, X., Yang, Y., Su, J.C., Zheng, M., Yamamoto-Hanada, K., Teixeira, H.D., Irvine, A.D., Efficacy and Safety of Upadacitinib Treatment in Adolescents with Moderate-to-Severe Atopic Dermatitis: Analysis of the Measure Up 1, Measure Up 2, and AD Up Randomized Clinical Trials, JAMA Dermatology, 159, (5), 2023, p526-535Journal Article, 2023
Flohr, C., Rosala-Hallas, A., Jones, A.P., Beattie, P., Baron, S., Browne, F., Brown, S.J., Gach, J.E., Greenblatt, D., Hearn, R., Hilger, E., Esdaile, B., Cork, M.J., Howard, E., Lovgren, M.-L., August, S., Ashoor, F., Williamson, P.R., McPherson, T., O"Kane, D., Ravenscroft, J., Shaw, L., Sinha, M.D., Spowart, C., Taams, L.S., Thomas, B.R., Wan, M., Sach, T.H., Irvine, A.D., Efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children and young people (TREAT): A multicentre parallel group assessor-blinded clinical trial, British Journal of Dermatology, 189, (6), 2023, p674-684Journal Article, 2023
Siegfried, E.C., Arkin, L.M., Chiu, Y.E., Hebert, A.A., Callen, J.P., Castelo-Soccio, L., Co, D.O., Cordoro, K.M., Curran, M.L., Dalrymple, A.M., Flohr, C., Gordon, K.B., Hanna, D., Irvine, A.D., Kim, S., Kirkorian, A.Y., Lara-Corrales, I., Lindstrom, J., Paller, A.S., Reyes, M., Begolka, W.S., Tom, W.L., Van Voorhees, A.S., Vleugels, R.A., Lee, L.W., Davies, O.M.T., Brandling-Bennett, H.A., Methotrexate for inflammatory skin disease in pediatric patients: Consensus treatment guidelines, Pediatric Dermatology, 40, (5), 2023, p789-808Journal Article, 2023
Ismail, M., Doelger, E., Eckert, D., Irvine, A.D., Chu, A.D., Teixeira, H.D., Liu, W., Nader, A., Population pharmacokinetic and exposure-response modelling to inform upadacitinib dose selection in adolescent and adult patients with atopic dermatitis, British Journal of Clinical Pharmacology, 89, (10), 2023, p3139-3151Journal Article, 2023
Eyerich, K., Gooderham, M.J., Silvestre, J.F., Shumack, S.P., Mendes-Bastos, P., Aoki, V., Ortoncelli, M., Silverberg, J.I., Teixeira, H.D., Chen, S.H., Calimlim, B.M., Takemoto, S., Sancho, C., Fritz, B., Irvine, A.D., Real-world clinical, psychosocial and economic burden of atopic dermatitis: Results from a multicountry study, Journal of the European Academy of Dermatology and Venereology, 2023Journal Article, 2023
Paller, A.S., Flohr, C., Eichenfield, L.F., Irvine, A.D., Weisman, J., Soung, J., Pinto Correia, A., Natalie, C.R., Rodriguez Capriles, C., Pierce, E., Reifeis, S., Gontijo Lima, R., Armengol Tubau, C., Laquer, V., Weidinger, S., Safety and Efficacy of Lebrikizumab in Adolescent Patients with Moderate-to-Severe Atopic Dermatitis: A 52-Week, Open-Label, Phase 3 Study, Dermatology and Therapy, 13, (7), 2023, p1517-1534Journal Article, 2023
Guttman-Yassky, E., Thyssen, J.P., Silverberg, J.I., Papp, K.A., Paller, A.S., Weidinger, S., Chih-ho Hong, H., Hendrickson, B., Dilley, D., Tenorio, A.R., Ladizinski, B., Chu, A.D., Liu, J., Irvine, A.D., Safety of upadacitinib in moderate-to-severe atopic dermatitis: An integrated analysis of phase 3 studies, Journal of Allergy and Clinical Immunology, 151, (1), 2023, p172-181Journal Article, 2023
Burmester, G.R., Cohen, S.B., Winthrop, K.L., Nash, P., Irvine, A.D., Deodhar, A., Mysler, E., Tanaka, Y., Liu, J., Lacerda, A.P., Palac, H., Shaw, T., Mease, P.J., Guttman Yassky, E., Safety profile of upadacitinib over 15 000 patient-years across rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and atopic dermatitis, RMD Open, 9, (1), 2023Journal Article, 2023
Musters, A.H., Broderick, C., Prieto-Merino, D., Chiricozzi, A., Damiani, G., Peris, K., Dhar, S., De, A., Freeman, E., Arents, B.W.M., Burton, T., Bosma, A.L.-A.L., Chi, C.-C., Fletcher, G., Drucker, A.M., Kabashima, K., de Monchy, E.F., Panda, M., Wall, D.R., Vestergaard, C., Mahé, E., Bonzano, L., Kattach, L., Napolitano, M., Ordoñez-Rubiano, M.F., Haufe, E., Patruno, C., Irvine, A.D., Spuls, P.I., Flohr, C., The effects of systemic immunomodulatory treatments on COVID-19 outcomes in patients with atopic dermatitis: Results from the global SECURE-AD registry, Journal of the European Academy of Dermatology and Venereology, 37, (2), 2023, p365-381Journal Article, 2023
Guttman-Yassky, E., Irvine, A.D., Brunner, P.M., Kim, B.S., Boguniewicz, M., Parmentier, J., Platt, A.M., Kabashima, K., The role of Janus kinase signaling in the pathology of atopic dermatitis, Journal of Allergy and Clinical Immunology, 152, (6), 2023, p1394-1404Journal Article, 2023
Beck, L.A., Bieber, T., Weidinger, S., Tauber, M., Saeki, H., Irvine, A.D., Eichenfield, L.F., Werfel, T., Arlert, P., Jiang, L., Røpke, M., Paller, A.S., Tralokinumab treatment improves the skin microbiota by increasing the microbial diversity in adults with moderate-to-severe atopic dermatitis: Analysis of microbial diversity in ECZTRA 1, a randomized controlled trial, Journal of the American Academy of Dermatology, 88, (4), 2023, p816-823Journal Article, 2023
Augustin, M., Nosbaum, A., Werfel, T., Grond, S., Reed, C., Lampropoulou, A., Tietz, N., Irvine, A.D., Riedl, E., Treatment satisfaction of adult patients with moderate-to-severe atopic dermatitis treated with baricitinib in France, Germany, and the United Kingdom: results from a cross-sectional international patient survey, Journal of Dermatological Treatment, 34, (1), 2023Journal Article, 2023
Silverberg, J.I., Guttman-Yassky, E., Thaçi, D., Irvine, A.D., Stein Gold, L., Blauvelt, A., Simpson, E.L., Chu, C.-Y., Liu, Z., Gontijo Lima, R., Pillai, S.G., Seneschal, J., Two Phase 3 Trials of Lebrikizumab for Moderate-to-Severe Atopic Dermatitis, New England Journal of Medicine, 388, (12), 2023, p1080-1091Journal Article, 2023
Nicole Fagan, Fiona Browne, Veronika Dvorakova, Áine Carroll, Alan D Irvine, `Guidelines are not the issue, access to support and advice is the problem": a cross-sectional survey of general practitioners referring to paediatric dermatology, Clinical and Experimental Dermatology, 49, (1), 2023, p71-72Journal Article, 2023
Alan D. Irvine, Thishi Surendranathan, Liz Hennessy, Ivana Rajkovic, Annette Durkan, Dearbhla Coughlan, Sean Conlon, Richard Hudson, A real"world retrospective observational study exploring resource use for secondary care management of moderate"to"severe atopic dermatitis in children and adolescents at a single site in Ireland, JEADV Clinical Practice, 2, (3), 2023, p465-478Journal Article, 2023
Thomas Bieber, Jacob P Thyssen, Alan D Irvine, Yuichiro Tsunemi, Yun-Fei Chen, Luna Sun, Andrea Schloebe, Elisabeth Riedl, Michael J Cork, Early improvements in signs and symptoms predict clinical response to baricitinib in patients with moderate-to-severe atopic dermatitis, Clinical and Experimental Dermatology, 48, (8), 2023, p881-888Journal Article, 2023
Carsten Flohr, Alan D Irvine, Michael J Cork, Eric L Simpson, Andreas Wollenberg, Mette Deleuran, Amy Praestgaard, Ryan B Thomas, Ana B Rossi, Dupilumab improves patient-reported symptoms and health-related quality of life in children aged 6"11 years with severe atopic dermatitis, British Journal of Dermatology, 189, (2), 2023, p238-240Journal Article, 2023
Cathal O'Connor, Vicki Livingstone, Jonathan O"B Hourihane, Alan D. Irvine, Geraldine Boylan, Deirdre Murray, Early emollient bathing is associated with subsequent atopic dermatitis in an unselected birth cohort study, Pediatric Allergy and Immunology, 34, (7), 2023Journal Article, 2023
Carol Ní Chaoimh, Dhanis Lad, Claudio Nico, Gerwin J. Puppels, X. F. Colin C. Wong, John E. Common, Deirdre M. Murray, Alan D. Irvine, Jonathan O"Brien Hourihane, Early initiation of short"term emollient use for the prevention of atopic dermatitis in high"risk infants"The STOP"AD randomised controlled trial, Allergy, 78, (4), 2023, p984-994Journal Article, 2023
Alan D. Irvine, Jonathan O'. B. Hourihane, Reply to correspondence "Food allergens to emollients", Allergy, 78, (4), 2023, p1123-1123Journal Article, 2023
Mussa, Alessandro, Leoni, Chiara, Iacoviello, Matteo, Carli, Diana, Ranieri, Carlotta, Pantaleo, Antonino, Buonuomo, Paola Sabrina, Bagnulo, Rosanna, Ferrero, Giovanni Battista, Bartuli, Andrea, Melis, Daniela, Maitz, Silvia, Loconte, Daria Carmela, Turchiano, Antonella, Piglionica, Marilidia, De Luisi, Annunziata, Susca, Francesco Claudio, Bukvic, Nenad, Forleo, Cinzia, Selicorni, Angelo, Zampino, Giuseppe, Onesimo, Roberta, Cappuccio, Gerarda, Garavelli, Livia, Novelli, Chiara, Memo, Luigi, Morando, Carla, Della Monica, Matteo, Accadia, Maria, Capurso, Martina, Piscopo, Carmelo, Cereda, Anna, Di Giacomo, Marilena Carmela, Saletti, Veronica, Spinelli, Alessandro Mauro, Lastella, Patrizia, Tenconi, Romano, Dvorakova, Veronika, Irvine, Alan D., Resta, Nicoletta, Genotypes and phenotypes heterogeneity in PIK3CA-related overgrowth spectrum and overlapping conditions: 150 novel patients and systematic review of 1007 patients with PIK3CA pathogenetic variants, Journal of Medical Genetics, 60, (2), 2023, p163-173Journal Article, 2023
Bieber, T., Feist, E., Irvine, A.D., Harigai, M., Haladyj, E., Ball, S., Deberdt, W., Issa, M., Grond, S., Taylor, P.C., A Review of Safety Outcomes from Clinical Trials of Baricitinib in Rheumatology, Dermatology and COVID-19, Advances in Therapy, 39, (11), 2022, p4910-4960Journal Article, 2022
Werfel, T., Irvine, A.D., Bangert, C., Seneschal, J., Grond, S., Cardillo, T., Brinker, D., Zhong, J., Riedl, E., Wollenberg, A., An integrated analysis of herpes virus infections from eight randomized clinical studies of baricitinib in adults with moderate-to-severe atopic dermatitis, Journal of the European Academy of Dermatology and Venereology, 36, (9), 2022, p1486-1496Journal Article, 2022
Kezic, S., McAleer, M.A., Jakasa, I., Goorden, S.M.I., der Vlugt, K.G.-V., Beers-Stet, F.S., Meijer, J., Roelofsen, J., Nieman, M.M., van Kuilenburg, A.B.P., Irvine, A.D., Children with atopic dermatitis show increased activity of ß-glucocerebrosidase and stratum corneum levels of glucosylcholesterol that are strongly related to the local cytokine milieu, British Journal of Dermatology, 186, (6), 2022, p988-996Journal Article, 2022
Paller, A.S., Guttman-Yassky, E., Schuttelaar, M.L.A., Irvine, A.D., Baselga, E., Kataoka, Y., Antila, M., de Bruin-Weller, M.S., Marcoux, D., Abramova, A., Rizova, E., Liu, C., Zhang, A., Disease characteristics, comorbidities, treatment patterns and quality of life impact in children <12 years old with atopic dermatitis: Interim results from the PEDISTAD Real-World Registry, Journal of the American Academy of Dermatology, 87, (5), 2022, p1104-1108Journal Article, 2022
Budu-Aggrey, A., Kilanowski, A., Sobczyk, M.K., Shringarpure, S.S., Mitchell, R., Reis, K., Reigo, A., Mägi, R., Nelis, M., Tanaka, N., Brumpton, B.M., Thomas, L.F., Sole-Navais, P., Flatley, C., Espuela-Ortiz, A., Herrera-Luis, E., Lominchar, J.V.T., Bork-Jensen, J., Marenholz, I., Arnau-Soler, A., Jeong, A., Fawcett, K.A., Baurecht, H., Rodriguez, E., Alves, A.C., Kumar, A., Sleiman, P.M., Chang, X., Medina-Gomez, C., Hu, C., Xu, C.-J., Qi, C., El-Heis, S., Titcombe, P., Antoun, E., Fadista, J., Wang, C.A., Thiering, E., Xiao, S., Kress, S., Kothalawala, D.M., Kadalayil, L., Duan, J., Zhang, H., Hoffmann, T., Jorgenson, E., Choquet, H., Risch, N., Njølstad, P., Andreassen, O.A., Johansson, S., Almqvist, C., Gong, T., Ullemar, V., Karlsson, R., Magnusson, P.K.E., Szwajda, A., Burchard, E.G., Thyssen, J.P., Hansen, T., Kårhus, L.L., Dantoft, T.M., Jeanrenaud, A.C.S.N., Ghauri, A., Arnold, A., Homuth, G., Lau, S., Nöthen, M.M., Hübner, N., Imboden, M., Visconti, A., Falchi, M., Bataille, V., Hysi, P., Ballardini, N., Boomsma, D.I., Hottenga, J.J., Müller-Nurasyid, M., Ahluwalia, T.S., Stokholm, J., Chawes, B., Schoos, A.-M., Esplugues, A., Bustamante, M., Raby, B., Arshad, H., German, C., Esko, T., Milani, L.A., Metspalu, A., Terao, C., Abuabara, K., Løset, M., Hveem, K., Jacobsson, B., Pino-Yanes, M., Strachan, D.P., Grarup, N., Linneberg, A., Lee, Y.-A., Probst-Hensch, N., Weidinger, S., Jarvelin, M.-R., Melén, E., Hakonarson, H., Irvine, A.D., Jarvis, D.L., Nijsten, T., Duijts, L., Vonk, J.M., Koppelmann, G.H., Godfrey, K.M., Barton, S.J., Feenstra, B., Pennell, C.E., Sly, P.D., Holt, P.G., Williams, K.L., Bisgaard, H., Bønnelykke, K., Curtin, J., Simpson, A., Murray, C., Schikowski, T., Bunyavanich, S., Weiss, S.T., Holloway, J.W., Min, J., Brown, S.J., Standl, M., Paternoster, L., European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation, medRxiv, 2022Journal Article, 2022
Ghaffarpour, N., Baselga, E., Boon, L.M., Diociaiuti, A., Dompmartin, A., Dvorakova, V., El Hachem, M., Gasparella, P., Haxhija, E., Kyrklund, K., Irvine, A.D., Kapp, F.G., Rößler, J., Salminen, P., van den Bosch, C., van der Vleuten, C., Kool, L.S., Vikkula, M., The VASCERN-VASCA working group diagnostic and management pathways for lymphatic malformations, European Journal of Medical Genetics, 65, (12), 2022Journal Article, 2022
Diociaiuti, A., Baselga, E., Boon, L.M., Dompmartin, A., Dvorakova, V., El Hachem, M., Gasparella, P., Haxhija, E., Ghaffarpour, N., Kyrklund, K., Irvine, A.D., Kapp, F.G., Rößler, J., Salminen, P., van den Bosch, C., van der Vleuten, C., Kool, L.S., Vikkula, M., The VASCERN-VASCA working group diagnostic and management pathways for severe and/or rare infantile hemangiomas, European Journal of Medical Genetics, 65, (6), 2022Journal Article, 2022
Cathal O"Connor, Alan D. Irvine, Deirdre Murray, Michelle Murphy, Jonathan O"B Hourihane, Geraldine Boylan, Study protocol: assessing SleeP IN infants with early-onset atopic Dermatitis by Longitudinal Evaluation (The SPINDLE study), BMC Pediatrics, 22, (1), 2022Journal Article, 2022
Nicholas Stefanovic, Conor J. Fitzmaurice, Patrick Ormond, Alan D. Irvine, Rupert B. Barry, Risk factors for distant metastasis in cutaneous squamous cell carcinoma, British Journal of Dermatology, 187, (3), 2022, p435-436Journal Article, 2022
Takuya Miyano, Alan D. Irvine, Reiko J. Tanaka, Model-Based Meta-Analysis to Optimize Staphylococcus aureus"Targeted Therapies for Atopic Dermatitis, JID Innovations, 2, (3), 2022, p100110Journal Article, 2022
Clowry Juliann, Dempsey Daniel J, Claxton Tracey J, Towell Aisling M, Turley Mary B, Sutton Marti, Geoghegan Joan A, Kezic Sanj, Jakasa Ivon, White Arthu, Irvine Alan D, McLoughlin Rachel M, Distinct T cell signatures are associated with Staphylococcus aureus skin infection in pediatric atopic dermatitis, 9, (9), 2024, p1-19Journal Article, 2024, DOI
Irvine AD, Corden LD, Swensson O, Swensson B, Moore JE, Frazer DG, Smith FJD, Knowlton RG, Christophers E, Rochels R, Uitto J, McLean WHI., Mutations in cornea-specific keratins K3 or K12 cause Meesmann's corneal dystrophy, Nature Genetics, 16, 1997, p184 - 187Journal Article, 1997, URL
Smith FJD, Irvine AD, Terron-Kwiatkowski A, Sandilands A, Campbell LE, Zhao Y, Liao L, Evans AT, Goudie DR, Lewis-Jones S, Arseculeratne G, Munro CS, Sergeant A, O'Regan G, Bale SJ, Compton JG, DiGiovanna JJ, Presland RB, Fleckman P, Irwin McLean WHI, Loss-of-function mutations in the filaggrin gene cause ichthyosis vulgaris, Nature Genetics, 38, (3), 2006, p337 - 342Journal Article, 2006, DOI , URL
Palmer CNA, Irvine AD, Terron-Kwiatkowski A, Zhao Y, Liao H, Lee SP, Goudie DR, Sandilands A, Campbell LE, Smith FJD, O'Regan GM, Watson RM, Cecil JE, Bale SJ, Compton JG, DiGiovanna JJ, Fleckman P, Lewis-Jones S, Arseculeratne G, Sergeant A, Munro CS, El Houate B, McElreavey K, Halkjaer LB, Bisgaard H, Mukhopadhyay S, McLean WHI, Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis, Nature Genetics, 38, (4), 2006, p441 - 446Journal Article, 2006, DOI , URL
Sandilands A, Terron-Kwiatkowski A, Hull PR, O'Regan GM, Clayton TH, Watson RM, Carrick T, Evans AT, Liao H, Zhao Y, Campbell LE, Schmuth M, Gruber R, Janecke AR, Elias PM, van Steensel MAM, Nagtzaam I, van Geel M, Steijlen PM, Munro CS, Bradley DG, Palmer CNA, Smith FJD, McLean WHI, Irvine AD, Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema , Nature Genetics, 39, (5), 2007, p650 - 654Journal Article, 2007, DOI , URL
Weidinger S, Illig T, Baurecht H, Irvine AD, Rodriguez E, Diaz-Lacava A, Klopp N, Wagenpfeil S, Zhao Y, Liao H, Lee SP, Palmer CNA, Jenneck C, Maintz L, Hagemann T, Behrendt H, Ring J, Nothen MM, McLean WHI, Novak N, Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations, Journal of Allergy and Clinical Immunology, 118, (1), 2006, p214 - 219Journal Article, 2006, DOI
Sandilands A, O'Regan GM, Smith FJD, McLean WHI, Irvine AD, Prevalent and Rare Mutations in the Gene Encoding Filaggrin Cause Ichthyosis Vulgaris and Predispose Individuals to Atopic Dermatitis, Journal of Investigative Dermatology, 126, 2006, p1770 - 1775Journal Article, 2006, DOI
Collins SM, Dominguez M, Ilmarinen T, C Costigan C, Irvine AD, Dermatological manifestations of autoimmune polyendocrinopathy - candidiasis - ectodermal dystrophy (APECED) syndrome, British Journal of Dermatology, 154, (6), 2006, p1088 - 1093Journal Article, 2006, DOI
Veugelers M, Wilkes D, Burton K, McDermott D, Song Y, Vaughan CJ, La Perle K, Goldstein G, Kligfield P, O'Hagan A, Bennett K, Meyer BJ, Legius E, Kartunnen M, Lavyne M, Neau J-P, Richter G, Kirali K, Stapleton K, Morelli P, Norio R, Takanashi Y, Farnsworth A, Bamforth J-S, Eitelberger F, Manfroi W, Ko GTC, Powers J, Mochizuki Y, Imai T, Driscoll DA, Goldmuntz E, Edelberg J, Eccles D, Irvine AD, McKnight GS, Basson CT, Comparative PRKAR1 a Genotype-Phenotype Analyses in Humans with Carney complex and prkar1 a Haploinsufficient Mice, Proceedings of The National Academy of Sciences, 101, (39), 2004, p14222 - 14227Journal Article, 2004, DOI
Terron-Kwiatkowski A, Terrinoni A, Didona B, Melino G, Atherton D, Irvine AD, Mclean WHI, Atypical Epidermolytic Palmoplantar Keratoderma Presentation Associated With A Mutation In The Keratin 1 Gene, British Journal of Dermatology, 150, (6), 2004, p1096 - 1103Journal Article, 2004, DOI
Irvine AD, Fleshing out filaggrin phenotypes, Journal of Investigative Dermatology, 127, (3), 2007, p504 - 507Journal Article, 2007, DOI
Irvine AD and McLean WHI, Breaking the (un) sound barrier: filaggrin is a major gene for atopic dermatitis, Journal of Investigative Dermatology, 126, (6), 2006, p1200 - 1202Journal Article, 2006, DOI
McLean WHI, Irvine AD, Hamill KJ, Whittock NV, Coleman CM, Mellerio JE, Ashton GS, Dopping-Hepenstal PJH, Eady RAJ, Jamil T, Phillips RJ, Shabbir SG, Haroon TS, Khurshid K, Moore JE, Page B, Darling J, Atherton DJ, Munro CS, Smith FJD, McGrath JA, An unusual N-terminal deletion of the laminin α3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome, Human Molecular Genetics, 12, (18), 2003, p2395 - 2409Journal Article, 2003, DOI
Wang LL, Gannavarapu A, Clericuzio CL, Erickson RP, Irvine AD, Plon SE, Absence of RECQL4 mutations in poikiloderma with neutropenia in Navajo and non-Navajo patients, American Journal of Medical Genetics A, 118, (3), 2003, p299 - 301Journal Article, 2003, DOI
McMullen EA, McCarron P, Irvine AD, Dolan OM, Allen GE, Association between long-term acitretin therapy and osteoporosis: no evidence of increased risk, Clinical and Experimental Dermatology, 28, (3), 2003, p307 - 309Journal Article, 2003, DOI
Terron-Kwiatkowski A, Paller AS, Compton J, Atherton DJ, McLean WHI, Irvine AD, Two cases of primarily palmoplantar keratoderma associated with novel mutations in keratin 1, Journal of Investigative Dermatology, 119, (4), 2002, p966 - 971Journal Article, 2002, DOI
Bitoun E, Chavanas S, Irvine AD, Lonie L, Bodemer C, Paradisi M, Hamel-Teillac, Ansai S, Mitsuhashi Y, Taïeb A, de Prost Y, Zambruna G, Harper JI, Hovnanian A, Netherton Syndrome: Disease expression and Spectrum of SPINK5 Mutations in 21 families, Journal of Investigative Dermatology, 118, (2), 2002, p352 - 361Journal Article, 2002, DOI
Irvine AD, Sun P, Kos L, Wang X, Paller AS, A colorimetric bead-binding assay for detection of intermolecular interactions, Experimental Dermatology, 11, (5), 2002, p465 - 471Journal Article, 2002, DOI
Irvine AD, Coleman CM,. Moore JE, Swensson O, Morgan SJ, McCarthy JH, Smith FJD, Black GCM, McLean WHI, A novel mutation in KRT12 associated with Meesmann's Epithelial Corneal Dystrophy, British Journal of Ophthalmology, 86, (7), 2002, p729 - 732Journal Article, 2002, DOI
McGrath JA, Duijf P, Doetsch V, Irvine AD, de Waal R, Vanmolkot K, Wessagowit VA, Kelly K, Atherton DJ, Griffiths WAD, Orlow SJ, van Haeringen A, Ausems M, Yang A, McKeon F, Bamshad MA, Brunner HG, Hamel BCJ, van Bokhoven H, Hay-Wells syndrome is caused by missense mutations in the SAM domain of p63, Human Molecular Genetics, 10, (3), 2001, p221 - 229Journal Article, 2001, URL
Irvine AD, Rugg EL, Lane EB, Hoare S, Peret C, Hughes AE, Heagerty AH, Molecular confirmation of the unique phenotype of epidermolysis bullosa simplex with mottled pigmentation, British Journal of Dermatology, 144, (1), 2001, p40 - 46Journal Article, 2001, DOI
Chavanas S, Bodemer C, Rochat A, Hamel-Teillac D, Ali M, Irvine AD, Bonafé J-L, Taïeb A, Barrandon Y, Harper JI, de Prost, Y, Hovnanian A, Mutations in SPINK5 encoding a novel serine protease inhibitor cause Netherton Syndrome, Nature Genetics, 25, (2), 2000, p141 - 142Journal Article, 2000, DOI , URL
Irvine AD, Smith FJD, Shum KW, Williams HC, McLean WHI, A novel mutation in the 2B domain of keratin 2e causing Ichthyosis Bullosa of Siemens, Clinical and Experimental Dermatology, 25, (8), 2000, p648 - 652Journal Article, 2000, DOI
Smith FJD, McKenna KE, Irvine AD, Bingham EA, Coleman CM, Uitto J, McLean WHI, A mutation detection strategy for the human keratin 6A gene and novel missense mutations in two cases of pachyonychia congenita type 1, Experimental Dermatology, 8, (2), 1999, p109 - 111Journal Article, 1999, DOI
Korge BP, Hamm H, Jury CS, Traupe H, Irvine AD, Healey E, Birch-Machin, M, Rees JL, Messenger AG, Holmes SC, Parry DAD, Munro CS, Identification of novel mutations in basic hair keratins hHb1 and hHb6 in monilethrix: implications for protein structure and clinical phenotype, Journal of Investigative Dermatology, 113, (4), 1999, p607 - 612Journal Article, 1999, DOI
Casey M, Mah C, Merliss AD, Kirschner LS, Taymans SE, Denio AE, Korf B, Irvine AD, Hughes AE, Carney JA, Stratakis CA, Basson CT, Identification of a novel genetic locus for familial cardiac myxoma and Carney complex, Circulation, 98, (23), 1998, p2560 - 2566Journal Article, 1998, URL
Ahmad W, Irvine AD, Lam H, Buckley C, Bingham EA, Panteleyev AA, Ahmad A, McGrath JA, Christiano AM, A missense mutation in the zinc-finger domain of the human hairless gene underlies congenital atrichia in a family of Irish travellers, American Journal of Human Genetics, 63, (4), 1998, p984 - 991Journal Article, 1998, DOI
Irvine AD, Armstrong DKB, Bingham EA, Hadden DR, Nevin NC, Hughes AE, Evidence for a second genetic locus in Carney complex, British Journal of Dermatology, 138, 1998, p572 - 576Journal Article, 1998, DOI
Covello SP, Irvine AD, McKenna KE, Munro CS, Nevin NC, Smith FJD, Uitto J, McLean WHI, Mutations in keratin K9 in kindreds with epidermolytic palmoplantar keratoderma and epidemiology in Northern Ireland, Journal of Investigative Dermatology, 111, 1998, p1207 - 1209Journal Article, 1998, DOI
Irvine AD, McKenna KE, Jenkinson H, Hughes AE, A mutation in the V1 Domain of keratin 5 causes Epidermolysis Bullosa Simplex with Mottled Pigmentation, Journal of Investigative Dermatology, 108, (5), 1997, p809 - 810Journal Article, 1997, DOI
Irvine AD, McKenna KE, Bingham EA, Nevin NC, Hughes AE, A novel mutation in the helix termination peptide of keratin 5 causing Epidermolysis bullosa simplex Dowling-Meara, Journal of Investigative Dermatology, 109, 1997, p815 - 816Journal Article, 1997, DOI
O'Connell S, O'Regan GM, Bolger T, Hoffman HM, Cant A, Irvine AD, Watson R, Response to Il-1-Receptor Antagonist in a child with Familial Cold Autoinflammatory Syndrome, Pediatric Dermatology, 24, (1), 2007, p85 - 89Journal Article, 2007, DOI
O'Regan GM, Canny G, Irvine AD, Peeling paint' dermatitis as a presenting sign of cystic fibrosis, Journal of Cystic Fibrosis, 5, (4), 2006, p257 - 259Journal Article, 2006, DOI
Dominguez M, Crushell E, Ilmarinen T, McGovern E, Collins S, Chang B, Fleming P, Irvine AD, Brosnahan D, Ulmanen I, Murphy N, Costigan C, Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED) in the Irish Population, Journal of Pediatric Endocrinology and Metabolism, 19, (11), 2006, p1343 - 1352Journal Article, 2006
Madasseri A, McDermott MB, Irvine AD, Lipoatrophic panniculitis of the ankles, Clinical and Experimental Dermatology, 31, (2), 2006, p303 - 530Journal Article, 2006, DOI
Tobin AM, Cotter M, Irvine AD, Kirby B, Successful treatment of a refractory verruca in a child with acute lymphoblastic leukaemia with topical cidofovir, British Journal of Dermatology, 152, (2), 2005, p386 - 388Journal Article, 2005, DOI
O'Hagan, AH, Irvine AD, Sands A, O'Donaghue D, Casey F, Bingham EA, Miliary Neonatal Hemangiomatosis with Fulminant Heart Failure and Cardiac Septal Hypertrophy in Two Infants, Pediatric Dermatology, 21, (4), 2004, p469 - 472Journal Article, 2004, DOI
Paller AS, Irvine AD, Russi DC, Raised limb bands developing in infancy, British Journal of Dermatology, 149, (2), 2003, p436 - 437Journal Article, 2003, DOI
Moore JE, Dua HS, Page AB, Irvine AD, Archer DB, Ocular surface reconstruction in LOGIC syndrome by amniotic membrane transplantation, Cornea, 20, (1), 2001, p753 - 756Journal Article, 2001, DOI
O'Hagan AH, Irvine AD, Brennan T, Walsh MY, Bingham EA, Fibrous histiocytoma in a nine week old male infant, European Journal of Pediatric Dermatology, 11, (1), 2001, p13 - 18Journal Article, 2001
O'Hagan A, Irvine AD, Walsh M, Allen GE, Pyodermatitis-pyostomatitis vegetans: evidence of an entirely mucocutaneous variant, British Journal of Dermatology, 138, (3), 1998, p552 - 555Journal Article, 1998, DOI
O'Hagan A, Irvine AD, Allen GE, Mefenamic acid induced pseudoporphyria, British Journal of Dermatology, 139, (6), 1998, p1131 - 1132Journal Article, 1998, DOI
Irvine AD, Bruce IN, Walsh MY, Bingham EA, Antineutrophil cytoplasmic antibodies in leukocytoclastic vasculitis, Archives of Dermatology, 134, (2), 1998, p239 - 240Journal Article, 1998, URL
Irvine AD, Bruce IN, Walsh MY, Bingham EA, Microscopic polyangiitis. Delineation of a cutaneous-limited variant associated with antimyeloperoxidase autoantibody., Archives of Dermatology, 133, (4), 1997, p474 - 477Journal Article, 1997, URL
Armstrong DKB, Irvine AD, Handley JM, Walsh MY, Hadden DR, Bingham EA, Carney complex: report of a new kindred with predominantly cutaneous manifestations, British Journal of Dermatology, 136, (4), 1997, p578 - 582Journal Article, 1997, DOI
Loughrey MB, Irvine AD, Girdwood RWA, McMillan CM, Cutaneous larva migrans: the case for routine oral treatment, British Journal of Dermatology, 137, (1), 1997, p155 - 158Journal Article, 1997
Irvine AD, Stewart FJ, Bingham EA, Nevin NC, Boston VE, Focal dermal hypoplasia (Goltz Syndrome) associated with intestinal malrotation and mediastinal dextroposition, American Journal of Medical Genetics, 62, (3), 1996, p213 - 215Journal Article, 1996, DOI
Irvine AD, Dolan OM, Hadden DR, Stewart FJ, Bingham EA, Nevin NC, An autosomal dominant syndrome of acromegaloid facial appearance and generalised hypertrichosis terminalis, Journal of Medical Genetics, 33, (11), 1996, p972 - 974Journal Article, 1996, URL
Irvine AD, Bruce IN, Walsh M, Burrows D, Handley J, Dermatological presentation of ANCA associated disease: a report of two contrasting cases and review of the literature, British Journal of Dermatology, 134, (5), 1996, p924 - 928Journal Article, 1996
Irvine AD, Sweeney LE, Corbett JR, Lymphangioma circumscriptum associated with paravesical cystic retroperitoneal lymphangioma, British Journal of Dermatology, 134, (6), 1996, p1135 - 1137Journal Article, 1996, DOI
Armstrong DKB, Irvine A, Walsh MY, Mayne EE, Burrows D, Multiple dermatofibromas in a patient with HIV infection, Clinical and Experimental Dermatology, 20, (6), 1995, p474 - 476Journal Article, 1995, DOI
Dolan OM, Burrows D, Irvine A, Walsh M, The value of a baseline liver biopsy prior to methotrexate therapy, British Journal of Dermatology, 131, (6), 1994, p891 - 894Journal Article, 1994, DOI
Irvine AD, Inherited defects in keratins, Clinics in Dermatology, 23, (1), 2005, p6-14Review, 2005, DOI
Irvine AD and McLean WHI, The Molecular Genetics of The Genodermatoses: Progress To Date And Future Directions, British Journal of Dermatology, 148, (1), 2003, p1-13Review, 2003, DOI
Irvine AD, Paller AS, The Molecular Genetics of the Inherited Disorders of Keratinization: An update, Advances in Dermatology, 18, 2002, p111-49Review, 2002
Irvine AD, Paller AS, Inherited disorders of Keratinization, Current Problems in Dermatology, 14, (3), 2002, p71-116Review, 2002, DOI
Irvine AD, Christiano AM, Hair on a gene string: recent advances in understanding the molecular genetics of hair loss, Clinical and Experimental Dermatology, 26, (1), 2001, p59-714Review, 2001, DOI
Irvine AD and McLean WHI, Human keratin diseases: the increasing spectrum of disease and the subtlety of genotype-phenotype correlation, British Journal of Dermatology, 140, (5), 1999, p815-828Review, 1999, DOI
Wen, Y, Liu, Y, Xu, Y, Zhao, Y, Hua, R, Wang, K, Sun, M, Li, Y, Yang, S, Zhang, XJ, Kruse, R, Cichon, S, Betz, RC, Nöthen, MM, van Steensel, MA, van Geel, M, Steijlen, PM, Hohl, D, Huber, M, Dunnill, GS, Kennedy, C, Messenger, A, Munro, CS, Terrinoni, A, Hovnanian, A, Bodemer, C, de Prost, Y, Paller, AS, Irvine, AD, Sinclair, R, Green, J, Shang, D, Liu, Q, Luo, Y, Jiang, L, Chen, HD, Lo, WH, McLean, WH, He, CD, Zhang, X, Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis., Nature genetics, 41, (2), 2009, p228 - 233Journal Article, 2009, DOI , URL
Cox, D, O' Regan, G, Collins, S, Byrne, A, Irvine, A, Watson, R, Juvenile localised scleroderma: a retrospective review of response to systemic treatment., Irish Journal of Medical Science, 177, (4), 2008, p343-346Journal Article, 2008, DOI , URL
Weidinger, S, Baurecht, H, Wagenpfeil, S, Henderson, J, Novak, N, Sandilands, A, Chen, H, Rodriguez, E, O'Regan, GM, Watson, R, Liao, H, Zhao, Y, Barker, JN, Allen, M, Reynolds, N, Meggitt, S, Northstone, K, Smith, GD, Strobl, C, Stahl, C, Kneib, T, Klopp, N, Bieber, T, Behrendt, H, Palmer, CN, Wichmann, HE, Ring, J, Illig, T, McLean, WH, Irvine, AD, Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk., The Journal of allergy and clinical immunology, 122, (3), 2008, p560-568.e4Journal Article, 2008, DOI , URL , TARA - Full Text
O'Regan, GM, Sandilands, A, McLean, WH, Irvine, AD, Filaggrin in atopic dermatitis., The Journal of Allergy and Clinical Immunology, 122, (4), 2008, p689-693Journal Article, 2008, DOI , URL
O'Regan, GM, Irvine, AD, The role of filaggrin loss-of-function mutations in atopic dermatitis., Current opinion in allergy and clinical immunology, 8, (5), 2008Journal Article, 2008, DOI , URL
Cusack, C, Fitzgerald, D, Clayton, TM, Irvine, AD, Successful treatment of florid cutaneous warts with intravenous cidofovir in an 11-year-old girl., Pediatric Dermatology, 25, (3), 2008, p387-389Journal Article, 2008, DOI , URL , TARA - Full Text
Brown, SJ, Irvine, AD, Atopic eczema and the filaggrin story., Seminars in cutaneous medicine and surgery, 27, (2), 2008, p128-137Journal Article, 2008, DOI , URL
Weidinger, S, O'Sullivan, M, Illig, T, Baurecht, H, Depner, M, Rodriguez, E, Ruether, A, Klopp, N, Vogelberg, C, Weiland, SK, McLean, WH, von Mutius, E, Irvine, AD, Kabesch, M, Filaggrin mutations, atopic eczema, hay fever, and asthma in children., The Journal of allergy and clinical immunology, 121, (5), 2008, p1203-1209.e1Journal Article, 2008, DOI , URL
Henderson, J, Northstone, K, Lee, SP, Liao, H, Zhao, Y, Pembrey, M, Mukhopadhyay, S, Smith, GD, Palmer, CN, McLean, WH, Irvine, AD, The burden of disease associated with filaggrin mutations: a population-based, longitudinal birth cohort study., The Journal of allergy and clinical immunology, 121, (4), 2008, p872-877Journal Article, 2008, DOI , URL
McLean, WH, Irvine, AD, Disorders of keratinisation: from rare to common genetic diseases of skin and other epithelial tissues., The Ulster Medical Journal, 76, (2), 2007, p72-82Journal Article, 2007, URL , TARA - Full Text
Sandilands, A, Smith, FJ, Irvine, AD, McLean, WH, Filaggrin's fuller figure: a glimpse into the genetic architecture of atopic dermatitis., The Journal of Investigative Dermatology, 127, (6), 2007, p1282-1284Journal Article, 2007, DOI , URL
O'Regan, GM, Zurada, J, Martinez-Mir, A, Christiano, AM, Irvine, AD, A recurrent splice-site mutation in the human hairless gene underlies congenital atrichia in Irish families., The British Journal of Dermatology, 156, (4), 2007, p744-747Journal Article, 2007, DOI , URL
Zhao, Y, Terron-Kwiatkowski, A, Liao, H, Lee, SP, Allen, MH, Hull, PR, Campbell, LE, Trembath, RC, Capon, F, Griffiths, CE, Burden, D, McManus, R, Hughes, R, Kirby, B, Rogers, SF, Fitzgerald, O, Kane, D, Barker, JN, Palmer, CN, Irvine, AD, McLean, WH, Filaggrin null alleles are not associated with psoriasis., The Journal of investigative dermatology, 127, (8), 2007, p1878-1882Journal Article, 2007, DOI , URL
O'Regan, GM, Watson, R, Orr, D, O'Donovan, D, Russell, J, Phelan, E, Ryan, M, Brosnahan, O, Irvine, A, Management of vascular birthmarks: review of a multidisciplinary clinic., Irish Medical Journal, 100, (4), 2007Journal Article, 2007, URL
Baurecht, H, Irvine, AD, Novak, N, Illig, T, Bühler, B, Ring, J, Wagenpfeil, S, Weidinger, S, Toward a major risk factor for atopic eczema: meta-analysis of filaggrin polymorphism data., The Journal of allergy and clinical immunology, 120, (6), 2007, p1406-1412Journal Article, 2007, DOI , URL
Sandilands, A, Sutherland, C, Irvine, AD, McLean, WH, Filaggrin in the frontline: role in skin barrier function and disease., Journal of Cell Science, 122, (Pt 9), 2009, p1285-1294Journal Article, 2009, DOI , URL , TARA - Full Text
Rodriguez S, Hall AJ, Granell R, McLean WH, Irvine AD, Palmer CN, Smith GD, Henderson J, Day IN, Carrier status for the common R501X and 2282del4 filaggrin mutations is not associated with hearing phenotypes in 5,377 children from the ALSPAC cohort, PLoS ONE, 4, (6), 2009, pe5784Journal Article, 2009, DOI , URL , TARA - Full Text
Rodríguez E, Baurecht H, Herberich E, Wagenpfeil S, Brown SJ, Cordell HJ, Irvine AD, Weidinger S, Meta analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease, Journal of Allergy and Clinical Immunology, 123, (6), 2009, p1361-1370.e7Journal Article, 2009, DOI
Sun M, Li N, Dong W, Chen Z, LiuQ, XuY, He G, Shi Y, Li X, Hao J, Luo Y, Shang D, Lv D, Ma F, Zhang D, Hua R, Lu C, Wen Y, Cao L, Irvine AD, McLean WHI, Dong Q, Wang M-R, Yu J, He L, Lo WHY, Zhang X, Copy number mutations on chromosome 17q24.2-q24.3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasia, American Journal of Human Genetics, 84, (6), 2009, p807-813.Journal Article, 2009, DOI
Irvine, AD., Towards a unified classification of the ectodermal dysplasias: Opportunities outweigh challenges. , American Journal Of Medical Genetics Part A, 149A, (9), 2009, p1970-1972Journal Article, 2009, DOI , TARA - Full Text
Field S, Irvine AD, Kirby B., The treatment of viral warts with topical cidofovir 1%: our experience of seven paediatric patients., British Journal of Dermatology, 160, (1), 2008, p223-224Journal Article, 2008, DOI
O'Regan, G.M., Irvine, A.D., Yao, N., O'Marcaigh, A., Sheridan-Pereira, M., Phelan, E., McDermott, M.B., (...), Watson, R., Mediastinal and neck kaposiform hemangioendothelioma , Pediatric Dermatology, 26, (3), 2009, p331-337Journal Article, 2009, DOI
Kezic S, Kemperman PMJH, Koster E, de Jongh C, Thio BH, Campbell LE, Irvine AD, McLean WHI, Puppels GJ, Caspers PJ, Loss-of-function mutations in the filaggrin gene lead to reduced levels of natural moisturizing factor in the stratum corneum, Journal of Investigative Dermatology, 128, (8), 2008, p2117-2119Journal Article, 2008, DOI
Genetics in, editor(s)Beiber T, Leung D , Atopic Dermatitis, London, Informa Healthcare, 2009, [Weidinger S, Rodriguez E, Irvine AD]Book Chapter, 2009
Genomics of the Epidermis and Appendages, Skin Pigmentation, And Skin Cancer in, editor(s)Kumar D, Weatherall D , Genomics and Clinical Medicine, New York , Oxford University Press, 2008, pp507-529 , [Healy E, Irvine AD, Lear JT, Munro CS]Book Chapter, 2008
Porokeratoses in, Wolff K, Katz S, Goldsmith L, Gilchrest B , Paller A, Leffell D , Fitzpatrick's Dermatology in General Medicine, New York , McGraw Hill, 2007, [O'Regan GM, Irvine AD]Book Chapter, 2007
Disorders of cornification in, Esterly N, Eichenfield L, Frieden I , Neonatal Dermatology, Philadelphia, Elsevier, 2007, pp285-310 , [Irvine AD, Paller AS ]Book Chapter, 2007
Dermatology in, editor(s)Strobel S, Smith P, El Habbal MH, Spitz, L, , The Great Ormond Street Colour Handbook of Paediatric Medicine and Surgery, London, Manson Publishing, 2007, pp131-159 , [Irvine AD, Lomas D, Atherton DJ, Harper JI ]Book Chapter, 2007
Genetics of Hidradenitis Suppurativa in, editor(s)Jemec GBE, Revuz J and Leyden JJ , Hirdadenitis Suppurativa, Berlin & Heidelberg , Springer, 2006, pp70-85 , [von der Werth J, Wood P, Irvine AD, McLean WHI ]Book Chapter, 2006
Ectodermal dysplasias in, editor(s)Harper JI, Oranje OP, Prose N , Pediatric Dermatology , Oxford , Blackwell Scientific, 2005, pp1412-1466 , [Irvine AD]Book Chapter, 2005
Epithelial corneal dystrophies. in, editor(s)Wang M, Flatten N , Cornea: Dystrophies and Degenerations: A Molecular Genetics Approach, San Francisco, Oxford University Press Inc, 2003, pp19-45 , [Irvine AD, Wang M, McLean WHI ]Book Chapter, 2003
Skin: Hereditary Disorders in, Cooper DN , Nature Encyclopaedia of the Human Genome, London., John Wiley and Sons Ltd, 2003, pp314-325 , [Corden LD, McLean WHI and Irvine AD]Book Chapter, 2003
Hair Loss: Genetics. in, editor(s)Cooper DN , Nature Encyclopaedia of the Human Genome, London , John Wiley and Sons Ltd, 2003, pp153-159 , [Irvine AD]Book Chapter, 2003
Hay-Wells syndrome. in, editor(s)Gruson ES , NORD Guide to Rare Disorders, Philadelphia , Lippincott, Williams & Wilkins, 2002, pp116-117 , [Irvine AD, McGrath JA]Book Chapter, 2002
Irvine AD, Stewart FJ, Bingham EA, Nevin NC, Boston VE, Focal dermal hypoplasia (Goltz Syndrome) associated with intestinal malrotation and mediastinal dextroposition., American Journal of Medical Genetics, 62, (3), 1996, p213-215Journal Article, 1996, DOI
McLean, W.H.I., Irvine, A.D., Hamill, K.J., Whittock, N.V., Coleman-Campbell, C.M., Mellerio, J.E., Ashton, G.S., (...), McGrath, J.A., Erratum: An unusual N-terminal deletion of the laminin α3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome, 2004, - 2395-2409Miscellaneous, 2004
Veugelers, M., Wilkes, D., Burton, K., McDermott, D.A., Song, Y., Goldstein, M.M., La Perle, K., (...), Basson, C.T., Erratum: Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice (Proceedings of the National Academy of Sciences of the United States of America (September 28, 2004) 101:39 (14222-14227)), 2004, - 15546Miscellaneous, 2004, DOI
O'Regan, G.M., Irvine, A.D., Disorders due to mutations in keratin genes , Giornale Italiano di Dermatologia e Venereologia, 140, (6), 2005, p667-676Journal Article, 2005
Clayton, T.H., Barry, J., Fitzgerald, D., Watson, R., Irvine, A.D., Clarithromycin suspension-associated toxic epidermal necrolysis in a 2-year-old girl [5] , Clinical and Experimental Dermatology , 32, (6), 2007, p755-756Journal Article, 2007, DOI
Liao, H., Sayers, J.M., Wilson, N.J., Irvine, A.D., Mellerio, J.E., Baselga, E., Bayliss, S.J., (...), Smith, F.J.D., A spectrum of mutations in keratins K6a, K16 and K17 causing pachyonychia congenita , Journal of Dermatological Science, 48, (3), 2007, p199-205Journal Article, 2007, DOI
McLean, W.H.I., Palmer, C.N.A., Henderson, J., Kabesch, M., Weidinger, S., Irvine, A.D., Filaggrin variants confer susceptibility to asthma , Journal of Allergy and Clinical Immunology, 121, (5), 2008, p1294-1295Journal Article, 2008, DOI
O'Regan GM, Kemperman PMJH, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Rowland M, Puppels GJ, McLean WHI, Caspers PJ Irvine AD, Raman Profiles of the Stratum Corneum Define Three FLG Genotype-determined Atopic Dermatitis Endophenotypes , Journal of Allergy and Clinical Immunology, 126, 2010, p574-580Journal Article, 2010, DOI
Bergboer JG, Zeeuwen PL, Irvine AD, Weidinger S, Giardina E, Novelli G, Heijer MD, Rodriguez E, Illig T, Riveira-Munoz E, Campbell LE, Tyson J, Dannhauser EN, O'Regan GM, Galli E, Klopp N, Koppelman GH, Novak N, Estivill X, McLean WH, Postma DS, Armour JA, Schalkwijk J, Deletion of Late Cornified Envelope 3B and 3C Genes Is Not Associated with Atopic Dermatitis, Journal of Investigative Dermatology, 130, 2010, p2057-2061Journal Article, 2010, DOI
O'Regan GM, Campbell LE, Cordell HJ, Irvine AD, McLean WHI, Brown SJ, Chromosome 11q13.5 variant associated with childhood eczema; an effect supplementary to filaggrin mutations, Journal of Allergy and Clinical Immunology, 125, 2010, p170-174Journal Article, 2010, DOI
Hackett BC, Fitzgerald D, Watson RM, Hol F.A, Irvine AD, Genotype-Phenotype Correlations with TGM1: Clustering of Mutations in the Bathing Suit Ichthyosis and Self Healing Collodion Baby Variants of Lamellar Ichthyosis, British Journal of Dermatology, 162, (2), 2010, p448-451Journal Article, 2010, DOI
Grainne M. O'Regan, Aileen Sandilands, WH Irwin McLean and Alan D. Irvine , Current Perspectives Series: Filaggrin in Atopic Dermatitis, Journal of Allergy and Clinical Immunology, 122, (4), 2008, p689-693Journal Article, 2008, DOI , URL , TARA - Full Text
Miajlovic H, Fallon PG, Irvine AD, Foster TJ., Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus, Journal of Allergy and Clinical Immunology, 126, (6), 2011, p1184-1190Journal Article, 2011, DOI , TARA - Full Text
Irvine AD, McLean WH, Leung DY, Filaggrin mutations associated with skin and allergic diseases., The New England journal of medicine, 365, (14), 2011, p1315-27Journal Article, 2011
Fleming P, Fitzgerald K, Watson R, Irvine A. , Response to "dental caries as a side effect of infantile hemangioma treatment with propanolol solution", Pediatric Dermatology, 28, 2011, p602 - 602Journal Article, 2011
Liao H, Irvine AD, Macewen CJ, Weed KH, Porter L, Corden LD, Gibson AB, Moore JE, Smith FJ, McLean WH, Moore CB, Development of Allele-Specific Therapeutic siRNA in Meesmann Epithelial Corneal Dystrophy., PloS one, 6, (12, e28582), 2011Journal Article, 2011, DOI , URL , TARA - Full Text
Knight J, Spain SL, Capon F, Hayday A, Nestle FO, Clop A, Wellcome Trust Case Control Consortium, Genetic Analysis of Psoriasis Consortium§, I-chip for Psoriasis Consortium, Barker JN. Weale ME, Trembath RC, Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis, Human Molecular Genetics, 21, (23), 2012, p5185 - 5192Journal Article, 2012, DOI , TARA - Full Text
Tsoi LC, Spain SL, Knight J, Ellinghaus E, Stuart PE, Capon F, Ding J, Li Y, Tejasvi T, Gudjonsson JE, Kang HM, Allen MH, McManus R, Novelli G, Samuelsson L, Schalkwijk J, Ståhle M, Burden AD, Smith CH, Cork MJ, Estivill X, Bowcock AM, Krueger GG, Weger W, Worthington J, Tazi-Ahnini R, Nestle FO, Hayday A, Hoffmann P, Winkelmann J, Wijmenga C, Langford C, Edkins S, Andrews R, Blackburn H, Strange A, Band G, Pearson RD, Vukcevic D, Spencer CC, Deloukas P, Mrowietz U, Schreiber S, Weidinger S, Koks S, Kingo K, Esko T, Metspalu A, Lim HW, Voorhees JJ, Weichenthal M, Wichmann HE, Chandran V, Rosen CF, Rahman P, Gladman DD, Griffiths CE, Reis A, Kere J, Nair RP, Franke A, Barker JN, Abecasis GR, Elder JT, Trembath RC, Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity., Nature genetics, 44, (12), 2012, p1341-1348Journal Article, 2012, DOI
Pohler E, Mamai O, Hirst J, Zamiri M, Horn H, Nomura T, Irvine AD, Moran B, Wilson NJ, Smith FJ, Goh CS, Sandilands A, Cole C, Barton GJ, Evans AT, Shimizu H, Akiyama M, Suehiro M, Konohana I, Shboul M, Teissier S, Boussofara L, Denguezli M, Saad A, Gribaa M, Dopping-Hepenstal PJ, McGrath JA, Brown SJ, Goudie DR, Reversade B, Munro CS, McLean WH, Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma., Nature genetics, 44, (11), 2012, p1272-6Journal Article, 2012, DOI , TARA - Full Text
Brown SJ, Kroboth K, Sandilands A, Campbell LE, Pohler E, Kezic S, Cordell HJ, McLean WH, Irvine AD, Intragenic copy number variation within filaggrin contributes to the risk of atopic dermatitis with a dose-dependent effect., The Journal of investigative dermatology, 132, (1), 2012, p98-104Journal Article, 2012
Hawkes CP, Hourihane JO, Kenny LC, Irvine AD, Kiely M, Murray DM, Gender- and gestational age-specific body fat percentage at birth., Pediatrics, 128, (3), 2011, pe645-51Journal Article, 2011, DOI , TARA - Full Text
Chen H, Common JE, Haines RL, Balakrishnan A, Brown SJ, Goh CS, Cordell HJ, Sandilands A, Campbell LE, Kroboth K, Irvine AD, Goh DL, Tang MB, van Bever HP, Giam YC, McLean WH, Lane EB, Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations., The British journal of dermatology, 165, (1), 2011, p106-14Journal Article, 2011
Brown SJ, Asai Y, Cordell HJ, Campbell LE, Zhao Y, Liao H, Northstone K, Henderson J, Alizadehfar R, Ben-Shoshan M, Morgan K, Roberts G, Masthoff LJ, Pasmans SG, van den Akker PC, Wijmenga C, Hourihane JO, Palmer CN, Lack G, Clarke A, Hull PR, Irvine AD, McLean WH, Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy., The Journal of allergy and clinical immunology, 127, (3), 2011, p661-7Journal Article, 2011, DOI , TARA - Full Text
Kezic S, O'Regan GM, Yau N, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Rowland M, McLean WH, Irvine AD, Levels of filaggrin degradation products are influenced by both filaggrin genotype and atopic dermatitis severity., Allergy, 66, (7), 2011, p934-40Journal Article, 2011, DOI , TARA - Full Text
Clericuzio C, Harutyunyan K, Jin W, Erickson RP, Irvine AD, McLean WH, Wen Y, Bagatell R, Griffin TA, Shwayder TA, Plon SE, Wang LL, Identification of a novel C16orf57 mutation in Athabaskan patients with Poikiloderma with Neutropenia., American journal of medical genetics. Part A, 155A, (2), 2011, p337-42Journal Article, 2011, DOI , TARA - Full Text
Strange A, Capon F, Spencer CC, Knight J, Weale ME, Allen MH, Barton A, Band G, Bellenguez C, Bergboer JG, Blackwell JM, Bramon E, Bumpstead SJ, Casas JP, Cork MJ, Corvin A, Deloukas P, Dilthey A, Duncanson A, Edkins S, Estivill X, Fitzgerald O, Freeman C, Giardina E, Gray E, Hofer A, Hüffmeier U, Hunt SE, Irvine AD, Jankowski J, Kirby B, Langford C, Lascorz J, Leman J, Leslie S, Mallbris L, Markus HS, Mathew CG, McLean WH, McManus R, Mössner R, Moutsianas L, Naluai AT, Nestle FO, Novelli G, Onoufriadis A, Palmer CN, Perricone C, Pirinen M, Plomin R, Potter SC, Pujol RM, Rautanen A, Riveira-Munoz E, Ryan AW, Salmhofer W, Samuelsson L, Sawcer SJ, Schalkwijk J, Smith CH, Ståhle M, Su Z, Tazi-Ahnini R, Traupe H, Viswanathan AC, Warren RB, Weger W, Wolk K, Wood N, Worthington J, Young HS, Zeeuwen PL, Hayday A, Burden AD, Griffiths CE, Kere J, Reis A, McVean G, Evans DM, Brown MA, Barker JN, Peltonen L, Donnelly P, Trembath RC, A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1., Nature genetics, 42, (11), 2010, p985-990Journal Article, 2010, DOI
Hackett BC, Phelan E, Ryan A, Kenny L, Murphy M, Irvine AD, Watson RM, Use of Systemic Corticosteroids in Management of a Large Congenital Haemangioma of the Scalp., Pediatric dermatology, 2012Journal Article, 2012
Crushell E, O'Leary D, Irvine AD, O'Shea A, Mayne PD, Reardon W, Methylenetetrahydrofolate reductase (MTHFR) deficiency presenting as a rash., American journal of medical genetics. Part A, 158A, (9), 2012, p2254-7Journal Article, 2012, DOI
Krawczyk J, McDermott M, Irvine AD, O'Marcaigh A, Storey L, Smith O, Skin involvement in Down syndrome transient abnormal myelopoiesis., British journal of haematology, 157, (3), 2012, p280Journal Article, 2012
Ricciardo B, Irvine A, McDermott M, Ryan J, Collins S, A case of congenital solitary Langerhans cell histiocytoma., The Australasian journal of dermatology, 52, (2), 2011, pe1-3Journal Article, 2011
Bracken J, Robinson I, Snow A, Watson R, Irvine AD, Rea D, Phelan E, PHACE syndrome: MRI of intracerebral vascular anomalies and clinical findings in a series of 12 patients., Pediatric radiology, 41, (9), 2011, p1129-38Journal Article, 2011
Scurr I, Wilson L, Lees M, Robertson S, Kirk E, Turner A, Morton J, Kidd A, Shashi V, Stanley C, Berry M, Irvine AD, Goudie D, Turner C, Brewer C, Smithson S, Cantú syndrome: report of nine new cases and expansion of the clinical phenotype., American journal of medical genetics. Part A, 155A, (3), 2011, p508-18Journal Article, 2011
Moriarty B, Bourke JF, Fitzgibbon J, Irvine AD, An unusual rash in a neonate. X-linked dominant ichthyosis (XLDI)., Clinical and experimental dermatology, 35, (3), 2010, pe62-4Journal Article, 2010
O'Regan GM, Irvine AD, Yao N, O'Marcaigh A, Sheridan-Pereira M, Phelan E, McDermott MB, Twomey A, Russell J, Watson R, Mediastinal and neck kaposiform hemangioendothelioma: report of three cases., Pediatric dermatology, 26, (3), 2009, p331-7Journal Article, 2009
McAleer MA, Irvine AD, The multifunctional role of filaggrin in allergic skin disease., The Journal of allergy and clinical immunology, 131, (2), 2013, p280-91Journal Article, 2013, DOI , TARA - Full Text
McLean WH, Irvine AD, Heritable filaggrin disorders: the paradigm of atopic dermatitis., The Journal of investigative dermatology, 132, (E1), 2012, pE20-1Journal Article, 2012, DOI , TARA - Full Text
McAleer MA, Flohr C, Irvine AD, Management of difficult and severe eczema in childhood., BMJ (Clinical research ed.), 345, 2012, pe4770Journal Article, 2012, TARA - Full Text
O'Regan GM, Irvine AD, The role of filaggrin in the atopic diathesis., Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 40, (7), 2010, p965-72Journal Article, 2010
McLean WH, Irvine AD, Old King Coal - molecular mechanisms underlying an ancient treatment for atopic eczema., The Journal of clinical investigation, 2013, p1-3Journal Article, 2013, DOI , TARA - Full Text
Irvine AD, Double trouble: homozygous dominant mutations and hair loss in pachyonychia congenita., The Journal of investigative dermatology, 132, (7), 2012, p1757-9Journal Article, 2012, DOI , TARA - Full Text
Irvine AD, Towards a unified classification of the ectodermal dysplasias: opportunities outweigh challenges., American journal of medical genetics. Part A, 149A, (9), 2009, p1970-2Journal Article, 2009
Irvine AD, Fleshing out filaggrin phenotypes., The Journal of investigative dermatology, 127, (3), 2007, p504-7Journal Article, 2007
Irvine AD, McLean WH, Breaking the (un)sound barrier: filaggrin is a major gene for atopic dermatitis., The Journal of investigative dermatology, 126, (6), 2006, p1200-2Journal Article, 2006
Porokeratoses in, editor(s)Goldsmith LA, Katz SI, Gilchrest BA, Paller A, Leffell DJ , Fitzpatrick's Dermatology in General Medicine , New York , McGraw Hill, 2012, ppxxx - xxx, [O'Regan GM, Irvine AD]Book Chapter, 2012
Ectodermal Dysplasias in, editor(s)Irvine AD, Hoeger PH, Yan A , Textbook of Pediatric Dermatology, London, Blackwell‐Wiley, 2011, pp1 - 127, [Asai Y, Irvine AD ]Book Chapter, 2011
Peeling Skin Syndrome in, editor(s)Schnacher L and Hansen R , Pediatric Dermatology, London, Mosby, 2010, pp1 - 23, [Irvine AD]Book Chapter, 2010
Other Syndromes associated with Ichthyosis in, editor(s)Schnacher L and Hansen R , Pediatric Dermatology , London, Mosby, 2010, pp612 - 614, [Irvine AD]Book Chapter, 2010
Ichthyosis Vulgaris in, editor(s)Schnacher L and Hansen R , Pediatric Dermatology, London, Mosby, 2010, pp578 - 580, [Irvine AD ]Book Chapter, 2010
Genetics and Genodermatoses in, editor(s)Burns T, Breathnach S, Cox N, Griffiths C , Rook's Textbook of Dermatology, Chichester , Wiley Blackwell, 2010, pp1 - 15.97, [Mellerio JE and Irvine AD]Book Chapter, 2010
Atopic Dermatitis: Genetics in, editor(s)Irvine AD, Hoeger PH, Yan A , Textbook of Pediatric Dermatology , London , Blackwell-Wiley, 2011, pp1 - 23, [Weidinger S, Irvine AD ]Book Chapter, 2011
Pediatric Dermatology in, editor(s)Irvine AD, Hoeger PH, Yan A , Harper's Textbook of Pediatric Dermatology , London, Blackwell-Wiley, 2011, pp2816 - [Weidinger S, Irvine AD]Book Chapter, 2011
Thawer-Esmail F, Jakasa I, Todd G, Wen Y, Brown SJ, Kroboth K, Campbell LE, O'Regan GM, McLean WH, Irvine AD, Kezic S, Sandilands A, South African amaXhosa patients with atopic dermatitis have decreased levels of filaggrin breakdown products but no loss-of-function mutations in filaggrin., The Journal of allergy and clinical immunology, 133, (1), 2014, p280-282.e2Journal Article, 2014, DOI , TARA - Full Text
Conte MI, Pescatore A, Paciolla M, Esposito E, Miano MG, Lioi MB, McAleer MA, Giardino G, Pignata C, Irvine AD, Scheuerle AE, Royer G, Hadj-Rabia S, Bodemer C, Bonnefont JP, Munnich A, Smahi A, Steffann J, Fusco F, Ursini MV, Insight into IKBKG/NEMO Locus: Report of New Mutations and Complex Genomic Rearrangements Leading to Incontinentia Pigmenti Disease., Human mutation, 2013Journal Article, 2013
Wall D, McMenamin M, O'Mahony D, Irvine AD, Kaposi sarcoma in an patient with atopic dermatitis treated with ciclosporin., BMJ case reports, 2013, 2013Journal Article, 2013, DOI , TARA - Full Text
Fahy CM, Fortune A, Quinn F, McMenamin ME, Browne PV, Langabeer S, McCarron S, Hayden P, Marren P, Ni Chonghaile M, Irvine AD, Vandenberghe E, Barnes L, Development of mycosis fungoides after bone marrow transplantation for chronic myeloid leukaemia; transmission from allogeneic donor., The British journal of dermatology, 2013Journal Article, 2013
Revencu N, Boon LM, Mendola A, Cordisco MR, Dubois J, Clapuyt P, Hammer F, Amor DJ, Irvine AD, Baselga E, Dompmartin A, Syed S, Martin-Santiago A, Ades L, Collins F, Smith J, Sandaradura S, Barrio VR, Burrows PE, Blei F, Cozzolino M, Brunetti-Pierri N, Vicente A, Abramowicz M, Désir J, Vilain C, Chung WK, Wilson A, Gardiner CA, Dwight Y, Lord DJ, Fishman L, Cytrynbaum C, Chamlin S, Ghali F, Gilaberte Y, Joss S, Boente Mdel C, Léauté-Labrèze C, Delrue MA, Bayliss S, Martorell L, González-Enseñat MA, Mazereeuw-Hautier J, O'Donnell B, Bessis D, Pyeritz RE, Salhi A, Tan OT, Wargon O, Mulliken JB, Vikkula M, RASA1 mutations and associated phenotypes in 68 families with capillary malformation-arteriovenous malformation., Human mutation, 34, (12), 2013, p1632-41Journal Article, 2013
Flohr C, Irvine AD, Systemic therapies for severe atopic dermatitis in children and adults., The Journal of allergy and clinical immunology, 132, (3), 2013, p774-774.e6Journal Article, 2013, DOI , TARA - Full Text
Samuelov L, Sarig O, Harmon RM, Rapaport D, Ishida-Yamamoto A, Isakov O, Koetsier JL, Gat A, Goldberg I, Bergman R, Spiegel R, Eytan O, Geller S, Peleg S, Shomron N, Goh CS, Wilson NJ, Smith FJ, Pohler E, Simpson MA, McLean WH, Irvine AD, Horowitz M, McGrath JA, Green KJ, Sprecher E, Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting., Nature genetics, 45, (10), 2013, p1244-8Journal Article, 2013, DOI , TARA - Full Text
Foley C, Moran B, McMenamin M, McDermott R, Ormond P, Irvine AD, Spontaneous regression of cutaneous metastases of squamous cell carcinoma., QJM : monthly journal of the Association of Physicians, 107, (1), 2014, p61-3Journal Article, 2014, DOI , TARA - Full Text
Weidinger S, Willis-Owen SA, Kamatani Y, Baurecht H, Morar N, Liang L, Edser P, Street T, Rodriguez E, O'Regan GM, Beattie P, Fölster-Holst R, Franke A, Novak N, Fahy CM, Winge MC, Kabesch M, Illig T, Heath S, Söderhäll C, Melén E, Pershagen G, Kere J, Bradley M, Lieden A, Nordenskjold M, Harper JI, McLean WH, Brown SJ, Cookson WO, Lathrop GM, Irvine AD, Moffatt MF, A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis., Human molecular genetics, 22, (23), 2013, p4841-56Journal Article, 2013, DOI , TARA - Full Text
Ellinghaus D, Baurecht H, Esparza-Gordillo J, Rodríguez E, Matanovic A, Marenholz I, Hübner N, Schaarschmidt H, Novak N, Michel S, Maintz L, Werfel T, Meyer-Hoffert U, Hotze M, Prokisch H, Heim K, Herder C, Hirota T, Tamari M, Kubo M, Takahashi A, Nakamura Y, Tsoi LC, Stuart P, Elder JT, Sun L, Zuo X, Yang S, Zhang X, Hoffmann P, Nöthen MM, Fölster-Holst R, Winkelmann J, Illig T, Boehm BO, Duerr RH, Büning C, Brand S, Glas J, McAleer MA, Fahy CM, Kabesch M, Brown S, McLean WH, Irvine AD, Schreiber S, Lee YA, Franke A, Weidinger S, High-density genotyping study identifies four new susceptibility loci for atopic dermatitis., Nature genetics, 45, (7), 2013, p808-12Journal Article, 2013, DOI , TARA - Full Text
Foley CC, McMenamin M, Gordon KD, Irvine AD, An unusual case of genital swelling., Clinical and experimental dermatology, 38, (8), 2013, p946-8Journal Article, 2013
Kelleher MM, O'Carroll M, Gallagher A, Murray DM, Dunn Galvin A, Irvine AD, Hourihane JO, Newborn transepidermal water loss values: a reference dataset., Pediatric dermatology, 30, (6), 2013, p712-6Journal Article, 2013
Langan SM, Irvine AD, Childhood eczema and the importance of the physical environment., The Journal of investigative dermatology, 133, (7), 2013, p1706-9Journal Article, 2013, DOI , TARA - Full Text
Irvine AD, Crossing barriers; restoring barriers? Filaggrin protein replacement takes a bow., The Journal of investigative dermatology, 134, (2), 2014, p313-4Journal Article, 2014, DOI , TARA - Full Text
Nason GJ, Baker JF, Seoighe D, Irvine AD, McDermott M, Orr D, Capra M, Kelly PM, Congenital-infantile fibrosarcoma of the foot--avoidance of amputation., Irish medical journal, 107, (5), 2014, p148-9Journal Article, 2014, URL
Cole C, Kroboth K, Schurch NJ, Sandilands A, Sherstnev A, O'Regan GM, Watson RM, Irwin McLean WH, Barton GJ, Irvine AD, Brown SJ, Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis., The Journal of allergy and clinical immunology, 134, (1), 2014, p82-91Journal Article, 2014, DOI , TARA - Full Text
Asai, Yuka Greenwood, Celia Hull, Peter R. Alizadehfar, Reza Ben-Shoshan, Moshe Brown, Sara J. Campbell, Linda Michel, Deborah L. Bussières, Johanne Rousseau, François Fujiwara, T. Mary Morgan, Kenneth Irvine, Alan D. McLean, W.H. Irwin Clarke, Ann , Filaggrin gene mutation associations with peanut allergy persist despite variations in peanut allergy diagnostic criteria or asthma status , Journal of Allergy and Clinical Immunology , 132 , (1 ), 2013, p239 - 242.e7Journal Article, 2013, DOI , URL , TARA - Full Text
Grant Reviewer: The Wellcome Trust, Medical Research Council (UK), The Italian National Telethon, DEBRA International, British Skin Foundation Current
Editorial Board: Journal of Lymphoedema 2007- present
Editorial Board Member: Faculty of 1000 Medicine (F1000), Paediatric Dermatology Section 2007- present
Reviewer: The Journal of Investigative Dermatology, The British Journal of Dermatology, Experimental Dermatology, European Journal of Human Genetics, Clinical and Experimental Dermatology, Journal of Allergy And Clinical Immunology, Allergy Current
/prod01/channel_3/media/tcd/medicine/clinical-medicine/images/staff-profiles/alanirvine.jpg)