Publications and Further Research Outputs
Peer-Reviewed Publications
Arzan Zarin, A. and Labrador, J.-P., Motor axon guidance in Drosophila, Seminars in Cell and Developmental Biology, 2019, p36-47
Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Emily Taylor, Greg Podgorski, Jeff Carmichael,, Biological Science, Global Edition, 6/e, global edition, 6/e, Pearson Global, 2018
Li H, Watson A, Olechwier A, Anaya M, Sorooshyari SK, Harnett D, Lee HP, Vielmetter J, Fares MA, Garcia KC, Özkan E, Labrador JP*, Zinn K*, Deconstruction of the beaten Path-Sidestep interaction network provides insights into neuromuscular system development., elife, 6, 2017, pe28111-
Asadzadeh J, Neligan N, Kramer SG, Labrador JP, Tinman Regulates NetrinB in the Cardioblasts of the Drosophila Dorsal Vessel., PloS one, 11, (2), 2016, pe0148526
Asadzadeh J, Neligan N, Canabal-Alvear JJ, Daly AC, Kramer SG, Labrador JP, The Unc-5 Receptor Is Directly Regulated by Tinman in the Developing Drosophila Dorsal Vessel., PloS one, 10, (9), 2015, pe0137688
Molecular Coevolution: Methods and Applications in, editor(s)Mario A Fares , Natural Selection: Methods and Applications, CRC Press, 2014, pp211 - 237, [Fares M.A., Labrador JP]
Zarin AA, Asadzadeh J, Hokamp K, McCartney D, Yang L, Bashaw GJ, Labrador JP, A transcription factor network coordinates attraction, repulsion, and adhesion combinatorially to control motor axon pathway selection., Neuron, 81, (6), 2014, p1297-311
Santiago C, Labrador JP, Bashaw GJ, The homeodomain transcription factor Hb9 controls axon guidance in Drosophila through the regulation of Robo receptors., Cell Reports, 7, (1), 2014, p153-65
Zarin AA, Asadzadeh J, Labrador JP, Transcriptional regulation of guidance at the midline and in motor circuits., Cellular and molecular life sciences : CMLS, 71, (3), 2013, p419-32
Zarin, A.A., Daly, A.C., Hülsmeier, J., Asadzadeh, J., Labrador, J.-P., A GATA/homeodomain transcriptional code regulates axon guidance through the Unc-5 receptor, Development , 139, (10), 2012, p1798-1805
Fares MA, Ruiz-González MX, Labrador JP, Protein coadaptation and the design of novel approaches to identify protein-protein interactions., IUBMB life, 63, (4), 2011, p264-71
Coleman HA, Labrador JP, Chance RK, Bashaw GJ., The Adam family metalloprotease Kuzbanian regulates the cleavage of the roundabout receptor to control axon repulsion at the midline., Development., 137, (14), 2010, p2417-2426
Labrador, J.P., O'Keefe, D., Yoshikawa, S., McKinnon, R.D., Thomas, J.B. and Bashaw, G.J., The homeobox transcription factor even-skipped regulates netrin-receptor expression to control dorsal motor-axon projections in Drosophila. , Curr Biol, 15, (15), 2005, p1413-1419
Labrador, JP; O'Keefe, D; Yoshikawa, S; McKinnon, RD: Thomas, JB; Bashaw, GJ, The homeobox transcription factor even-skipped regulates netrin-receptor expression to control dorsal motor-axon projections in Drosophila. , Current Biology, 15, (15), 2005, p1413-1419
Hu, H., Li, M., Labrador, J.P., McEwen, J., Lai, E.C., Goodman, C.S. and Bashaw, G.J. , Cross GTPase-activating protein (CrossGAP)/Vilse links the Roundabout receptor to Rac to regulate midline repulsion., Proceedings of the National Academy of Sciences, 102, (12), 2005, p4613-4618
Fan, X., Labrador, J.P., Hing, H. and Bashaw, G.J., Slit stimulation recruits Dock and Pak to the roundabout receptor and increases Rac activity to regulate axon repulsion at the CNS midline., Neuron, 40, (1), 2003, p113-127
Olaso, E., Labrador, J.P., Wang, L., Ikeda, K., Eng, F.J., Klein, R., Lovett, D.H., Lin, H.C. and Friedman, S.L., Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2. , J Biol Chem, 277, (5), 2002, p3606-3613
Ikeda, K., Wang, L.H., Torres, R., Zhao, H., Olaso, E., Eng, F.J., Labrador, J.P., Klein, R., Lovett, D., Yancopoulos, G.D., Friedman, S.L. and Lin, H.C. , Discoidin domain receptor 2 interacts with Src and Shc following its activation by type I collagen., J Biol Chem, 277, (21), 2002, p19206-19212.
Labrador, J.P., Azcoitia, V., Tuckermann, J., Lin, C., Olaso, E., Manes, S., Bruckner, K., Goergen, J.L., Lemke, G., Yancopoulos, G., Angel, P., Martinez, C. and Klein, R., The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism., EMBO Rep, 2, (5), 2001, p446-452
Bruckner, K.*, Labrador, J.P*., Scheiffele, P*., Herb, A.*, Seeburg, P.H. and Klein, R., EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains., Neuron, 22, (3), 1999, p511-524.
Manes, S., Mira, E., Gomez-Mouton, C., Lacalle, R.A., Keller, P., Labrador, J.P. and Martinez, A.C. , Membrane raft microdomains mediate front-rear polarity in migrating cells., EMBO J, 18, (22), 1999, p6211-6220
Labrador, J.P., Brambilla, R. and Klein, R., The N-terminal globular domain of Eph receptors is sufficient for ligand binding and receptor signaling., EMBO J, 16, (13), 1997, p3889-3897
Brambilla, R., Schnapp, A., Casagranda, F., Labrador, J.P., Bergemann, A.D., Flanagan, J.G., Pasquale, E.B. and Klein, R., Membrane-bound LERK2 ligand can signal through three different Eph-related receptor tyrosine kinases. , EMBO J, 14, (13), 1995, p3116-3126
Research Expertise
Projects
- Title
- SFI Principal Investigator (07/IN.1/B913)
- Summary
- Funding Agency
- SFI
- Date From
- 01/10/2007
- Date To
- 31/09/2011
- Title
- Trinity College Start-up grant
- Summary
- Date From
- 01/09/2007
- Date To
- 01/09/2008
- Title
- SFI RFP 2008 (08/RFP/NSC1617)
- Funding Agency
- SFI
- Date From
- 01/09/2008
- Date To
- 01/09/2011
- Title
- IRCSET Grant
- Summary
- Date From
- 01/09/2007
- Date To
- 01/09/2009
- Title
- IRCSET Grant
- Funding Agency
- IRCSET
- Date From
- 01/09/2009
- Date To
- 31/08/2012
- Title
- Trinity Research Award
- Date From
- 01/09/2009
- Date To
- 31/08/2012