Professor Brian O'Connell
Professor, Dental Science
Dean of Health Sciences, Fac Office - Faculty of Health Sciences
Publications and Further Research Outputs
Peer-Reviewed Publications
Meaney S, Connell BO, Elfadil S, Allen F, A qualitative investigation into patients' perspectives on edentulousness., Gerodontology, 34, (1), 2017, p79 - 85
Michael O'Sullivan, Brian C O'Connell, Multidisciplinary management of hypodontia , Prim Dent J, 6, (1), 2017, p62 - 73
O'Sullivan V and O'Connell BC, Water fluoridation, dentition status and bone health of older people in Ireland, Community Dentistry & Oral Epidemiology, 43, (1), 2015, p58 - 67
Al-Awadhi, E.A., Garvey, T.M., Alhag, M., Claffey, N.M., O'Connell, B., Efficacy of the Nance appliance as an anchorage-reinforcement method, American Journal of Orthodontics and Dentofacial Orthopedics, 147, (3), 2015, p330-338
McAuliffe P, Kim JH, Diamond D, Lau KT and O'Connell BC, A sleep bruxism detection system based on sensors in a splint, Journal of oral Rehabilitation, 42, (1), 2015, p34 - 39
Mcauliffe, P., Kim, J.H., Diamond, D., Lau, K.T., O'Connell, B.C., A sleep bruxism detection system based on sensors in a splint - pilot clinical data, Journal of Oral Rehabilitation, 42, (1), 2015, p34-39
Gallagher S, O'Connell BC ,O'Connell AC, Assessment of occlusion after placement of stainless steel crowns in children--a pilot study, Journal of Oral Rehabilitation, 41, (10), 2014, p730 - 736
Hashem A, Kelly A, O'Connell B, O'Sullivan M, Impact of moderate and severe hypodontia and amelogenesis imperfecta on quality of life and self-esteem of adult patients., Journal of dentistry, 41, (8), 2013, p689-94
O'Connell B, Prosthodontics at the crossroads: is this a 'golden age'?, Journal of the Irish Dental Association, 59, (2), 2013, p84-6
Harris D, Höfer S, O'Boyle CA, Sheridan S, Marley J, Benington IC, Clifford T, Houston F, O'Connell B, A comparison of implant-retained mandibular overdentures and conventional dentures on quality of life in edentulous patients: a randomized, prospective, within-subject controlled clinical trial., Clinical oral implants research, 24, (1), 2013, p96 - 103
Canning T, O'Connell BC, Houston F, O'Sullivan M, The effect of skeletal pattern on determining articulator settings for prosthodontic rehabilitation: an in vivo study., The International journal of prosthodontics, 24, (1), 2011, p16-25
Sharkey S, Kelly A, Houston FJ, O'Sullivan M, Quinn F and O'Connell BC, A Radiographic Analysis of Implant Component Misfit, International Journal of Oral & Maxillofacial Implants, 26, (4), 2011, p807 - 815
Sharkey S, Kelly A, Houston F, O'Sullivan M, Quinn F, O'Connell B, A radiographic analysis of implant component misfit., The International journal of oral & maxillofacial implants, 26, (4), 2011, p807-15
Condon M, Bready M, Quinn F, O'Connell BC, Houston FJ, O'Sullivan M, Maxillary anterior tooth dimensions and proportions in an Irish young adult population., Journal of oral rehabilitation, 2010
Brennan M, Houston FJ, O'Sullivan M and O'Connell BC, Patient Satisfaction and Oral Health Related Quality of Life Outcomes of Implant Overdentures and Fixed Complete Dentures, International Journal of Oral & Maxillofacial Implants, 25, (4), 2010, p791 - 800
Kim Jung Ho, McAuliffe P, O'Connell BC, Diamond D and Lau KT, Development of Wireless Bruxism Monitoring Device Based on Pressure Sensitive Polymer, Sensors and Actuators A, 163, (2), 2010, p486-492
Cellular & Molecular Biomechanics. in, editor(s)T. Clive Lee, Peter F. Niederer , Engineering for Medics and Biologists - An ESEM Primer: Studies in health technology and informatics, Online, IOP Press Online, 2010, pp202-213 , [Campbell VA, O'Connell B]
Campbell VA, O'Connell B, Cellular and molecular biomechanics., Technology and health care , 18, (3), 2010, p233-243
Atef A. Hashem, Brian O'Connell, June Nunn, Anne O'Connell, Therese Garvey, Michael O'Sullivan, Tooth agenesis in patients referred to an Irish tertiary care clinic for the developmental dental disorders, Journal of the Irish Dental Association, 56, (1), 2010, p23 - 27
Brennan M, Houston FJ, O'Sullivan M and O'Connell BC, Demographics of Implant Placement and Complications of a Patient Sub-Group in a Dental Hospital Population, Journal of the Irish Dental Association, 56, (2), 2010, p85 - 92
Fitzgerald M, O'Sullivan M, O'Connell BC and Houston FJ, Accuracy of Bone Mapping and Guided Flapless Implant Placement in Human Cadavers Using a Model-Based Planning Procedure, International Journal of Oral & Maxillofacial Implants, 25, (5), 2010, p999 - 1006
J.G. McGarry, P. Maguire, V.A. Campbell, B.C. O'Connell, P.J. Prendergast, S.P., Stimulation of Nitric Oxide Mechanotransduction in Single Osteoblasts Using Atomic Force Microscopy, Journal of Orthopedic research, 26, 2008, p513 - 521
Szlávik V, Szabó B, Vicsek T, Barabás J, Bogdán S, Gresz V, Varga G, O'Connell B,and Vag J, Differentiation of primary human submandibular gland cells cultured on basement, Tissue Eng Part A, 14, (11), 2008, p1915 - 1926
E. Byrne, E. Farrell, L. A. McMahon, M. G. Haugh, F. J. O'Brien, V. A. Campbell, P. J. Prendergast and B. C. O'Connell, Gene expression by marrow stromal cells in a porous collagen-glycosaminoglycan scaffold is affected by pore size and mechanical stimulation., J Mater Sci: Mater Med, 19, 2008, p3455 - 3463
Vanda Szlávik, János Vág, Károly Markó, Kornél Demeter, Emília Madarász, Imre Oláh, Tivadar Zelles, Brian C. O'Connell, Gábor Varga, Matrigel-induced acinar differentiation is followed by apoptosis in HSG cells., J Cell Biochem , 103, 2008, p284 - 295
B O'Connell and M O'Sullivan, Have Teeth Will Travel:Dental Tourism--Informing the Public, J Ir Dent Assoc, 53, 2007, p180 - 182
Vag, J., Byrne, E.M., Hughes, D.H., Hoffman, M.H., Ambudkar, I., Maguire, P. and O'Connell, B.C. , Morphological and Functional Differentiation of HSG cells: Role of Extracelleular Matrix and trpc1, J Cell Physiol , 212, (2), 2007, p416 - 423
P Maguire, JI Kilpatrick, G Kelly, PJ Prendergast VA Campbell, BC O'Connell and S Jarvis, Direct Mechanical Measurement of Geodesic Structures in Rat Mesenchymal Stem Cells, HFSP Journal, 1, (3), 2007, p181 - 191
Davis, S.T. and O'Connell, B.C., The Effect of Two Root Canal Sealers on the Retention of Glass Fibre Endodontic Posts, J. Oral Rehab, 34, 2007, p468 - 473
Deirdre H. Fitzgerald-Hughes, David C. Coleman and Brian C. O Connell, Identification of differentially-expressed proteins in derivatives of Candida albicans displaying a stable histatin-3 resistant phenotype, Antimicrobial Agents and Chemotherapy, 51, (8), 2007, p2793 - 2800
Farrell, E., Byrne, E.M., Fischer, J., O'Brien, F.J., O'Connell, B.C., Prendergast, P.J. and Campbell, V.A, A comparison of the osteogenic potential of adult rat mesenchymal stem cells cultured in 2-D and on 3-D collagen glycosaminoglycan scaffolds. , Technology and Health Care, 15, 2007, p19 - 31
Byrne D, Jacobs S, O'Connell B, Houston F, Claffey N, Preloads generated with repeated tightening in three types of screws used in dental implant assemblies, Journal of Prosthodontics, 15, (3), 2006, p164 - 171
Hashem, A.A., Claffey, N.C. and O'Connell, B.C., Pain and Anxiety Following the Placement of Dental Implants, J. Oral. Maxfac. Implants, 21, (6), 2006, p943 - 950
Farrell, E., Prendergast, P., O'Brien, F., O'Connell, B.C. and Campbell, V. A, Collagen-Glycosaminoglycans Scaffold Supports Adult Rat Mesenchymal Stem Cell Differentiation Along the Osteogenic and Chondrogenic Routes, Tissue Engineering, 12, (3), 2006, p459 - 468
Restoration of non-vital teeth in, editor(s)M. O'Sullivan , Quintessentials of Dental Practice: Fixed Prosthodontics in Dental Practice, London, Quintessence Publishing Co., 2005, pp139 - 158, [O'Connell, B.C.]
Yamagishi, H., Fitzgerald, D.H., Sein, T., Walsh, T.J. and O'Connell, B.C., Saliva affects the antifungal activity of exogenously added histatin 3 towards Candida albicans, FEMS Microbiology Lett, 244, (1), 2005, p207 - 212
Dagg, H., O'Connell, B., Claffey, N., Byrne, D. and Gorman, C., The influence of some different factors on the accuracy of shade selection., Journal of Oral Rehabilitation, 31, 2004, p900 - 904
Davis, S. and O'Connell, B.C., The provisional crown, J Irish Dent Assoc, 50, (4), 2004, p167 - 172
Fitzgerald, D.H., Coleman, D.C. and O'Connell, B.C., Susceptibility of Candida dubliniensis to Salivary Histatin 3, Antimicrob Agents Chemother, 47, (1), 2003, p70 - 76
Zheng, C., O"Connell, B.C., Baum, B.J., Inclusion of Moloney murine leukemia virus elements upstream of the transgene cassette in an E1- deleted adenovirus leads to an unusual genomic integration in epithelial cells, Virology, 313, (2), 2003, p460 - 472
Fitzgerald, D.H., Coleman, D.C. and O'Connell, B.C., Binding, Internalisation and Degradation of Histatin 3 in histatin resistant derivatives of Candida albicans, FEMS Microbiol Lett., 220, (2), 2003, p247 - 256
O"Connell, B.C., Zheng, C., Jacobson-Kram, D., Baum, B.J., Distribution and toxicity resulting from adenoviral administration to a single salivary gland in adult rats, J. Oral Path Med, 32, (7), 2003, p414 - 421
Schonherr, E., Schaefer, L., O'Connell, B.C. and Kresse, H., Matrix Metalloproteinase Expression by Endothelial Cells in Collagen Lattices Changes During Co-Culture with Fibroblasts and upon Induction of Decorin Expression, J. Cell Physiol., 187, (1), 2001, p37 - 47
Zheng, C., Hoque, A.T.M., Braddon, V.R., Baum, B.J. and O'Connell, B.C., Evaluation of Salivary Gland Acinar and Ductal Cell Specific Promoters In vivo with Recombinant Adenoviral Vectors, Hum. Gene Ther., 12, 2001, p2215 - 2223
Zheng, C., Goldsmith, C.M., O'Connell, B.C. and Baum, B.J., Adenoviral Vector Cytotoxicity Depends in Part on the Transgene Encoded, Biochemical and Biophysical Research Communications, 274, 2000, p767 - 771
Zheng, C., Baum, B.J., Iadarola, M.J. and O'Connell, B.C., Genomic Integration and Long Term Expression by a Modified Adenoviral Vector, Nature Biotechnol, 18, (2), 2000, p176 - 180
Baum, B.J., Goldsmith, C.M., Hoque, A.T.M., Wellner, R.B., Baccaglini, L., Ding, C., Yamano, S., Zheng, C., Aframian, D.J. and O'Connell, B.C., Salivary Glands as a Model for Craniofacial Applications of Gene Transfer, Int J. Oral & Maxillofac Surg, 29, 2000, p163 - 166
Liu, X., Wang, W., Singh, B.B., Lockwich, T., Jadlowiec, J., O'Connell, B.C., Wellner, R., Zhu, M.X. and Ambudkar, I.S., Trp1, a Candidate Protein for the Store-Operated Ca(+2) Influx Mechanism in Salivary Gland Cells, J. Biol. Chem., 275, (5), 2000, p3403 - 3411
Hoque, A.T.M.S., Liu, X., Kagami, H. Swaim, W.D., Wellner, R.B., O'Connell, B.C., Ambudkar, I.S., and Baum, B.J., Construction and function of a recombinant adenovirus encoding a human aquaporin 1-green fluorescence protein fusion product, Cancer Gene Ther., 7, 2000, p476 - 485
He, L., Liu, J., Collins, I., Sanford, S., O'Connell, B.C., Benham, C.J., and Levens, D., Loss of FBP Function Arrests Cell Proliferation and Extinguishes c-myc Expression, EMBO J, 19, (5), 2000, p1034 - 1044
Jung, D.W., Hecht, D., Ho, S.W., O'Connell, B.C., Kleinman, H.K. and Hoffman, M.P., PKC and ERK 1/2 Regulate Amylase Promoter Activity During Differentiation of a Salivary Gland Cell Line, J.Cell Physiol., 185, (2), 2000, p215 - 225
Schönherr, E., O'Connell, B.C., Schittny, J., Robenek, H., Fastermann, D., Fisher, L.W., Plenz, G., Vischer, P., Young, M.F. and Kresse, H., Paracrine or virus-mediated induction of decorin expression by endothelial cells contributes to tube formation and prevention of apoptosis in collagen lattices, Eur. J. Cell Biol., 78, 1999, p44 - 45
Wang, S., Baum, B.J., Kagami, H., Zheng, C., O'Connell, B.C., and Atkinson, J.C., Effect of clodronate on macrophage depletion and adenoviral-mediated transgene expression in salivary glands, J. Oral Pathol. Med., 28, 1999, p145 - 151
DeNichilo, M.O., Katz, B., O'Connell, B.C. and Yamada, K.M., Adenovirus-Mediated Gene Delivery of pp125FAK into Cultured Human Macrophages Deficient in This Protein Directs p50CSK Localization to Focal Contacts and Regulated MAP Kinase, J. Cell Physiol., 178, 1999, p164 - 172
Connell, A.C., Baccaglini, L., Fox, P.C., O'Connell, B.C., Kenshalo, D., Oweisy, H., Hoque, A.T.M., Sun, D., Herscher, L.L., Braddon, V.R., Delporte, C. and Baum, B., Efficacy of Adenovirus-mediated Transfer of the Human Aquaporin 1 cDNA to Irradiated Parotid Glands of Non-human Primates, Cancer Gene Ther, 6, (6), 1999, p505 - 513
Baum, B.J. and O'Connell, B.C., Vivo Gene Transfer to Salivary Glands, Crit. Rev. Oral Biol.Med., 10, (3), 1999, p276 - 283
Sommer, B., Kuznetsov, S.A., Gehron Robey, P., O'Connell, B.C., Cristiano. R.J. and Young, M.F., Efficient Gene Transfer into Normal Human Skeletal Cells Using Recombinant Adenovirus and Conjugated Adenovirus-DNA Complexes, Calc. Tissue Int., 64, 1999, p45 - 49
Wang, W., O'Connell, B.C., Dykeman, R., Sakai., Delporte, C., Swaim, W., Zhu, X., Birnbaumer, L. and Ambudkar, I., Cloning of TRP1b isoform from rat brain: immunodetection and localization of the endogenous Trp 1 protein, Am. J. Physiol, 45, (5), 1999, pC969 - C979
Brennan, M.T., O'Connell, B.C., Rams, T.E. and O'Connell, A.C., Management of Gingival Overgrowth Associated with Generalized Enamel Defects in a Child, J Clin Pediatr Dent, 23, (2), 1999, p97 - 102
Xu, YY, Histatin 3-Mediated Killing of Candida Albicans: Effect of Extracellular Salt Concentration on Binding and Internalization, Antimicrobial Agents and Chemotherapy, 43, 1999, p2256 - 2262
Baum, B.J. and O'Connell, B.C., The need to introduce gene therapy to the dental curriculum, Eur J Dent Educ, 3, 1999, p49 - 51
Mannes, A.J., Caudle, R.M., O'Connell, B.C. and Iadarola, M.J., Adenoviral Gene Transfer to Spinal Cord Neurons: Intrathecal vs. Intraparenchymal Administration, Brain Res., 793, (1-2), 1998, p1 - 6
Baum, B.J., Atkinson, J., Baccaglini, L., Berkman, M., Brahim, J., Davis, V., Lancaster, H., Marmary, Y., O'Connell, A., O'Connell, B., Wang, S., Xu, Y., Yamagishi, H. and Fox, P., The Mouth is a Gateway to the Body: Gene Therapy in 21st Century Dental Practice, CDA Journal, 26, (6), 1998, p455 - 460
O'Connell, B.C., Lillibridge, C.D., Ambudkar, I. and Kruse, D., Somatic Gene Transfer to Salivary Glands, Ann. NY Acad. Sci., 842, 1998, p171 - 180
Kagami, H., Atkinson, J.A., Handelman, B., Yu, S., Baum, B. and O'Connell, B.C., Repetitive Adenovirus Administration to Parotid Gland: Role of Immunological Barriers and Induction of Oral Tolerance, Hum. Gene Ther., 9, 1998, p305 - 313
Zheng, C., Hoffman, M.P., McMillan, T., Kleinman, H.K. and O'Connell, B.C., Growth Factor Regulation of the Amylase Promoter in Differentiating Salivary Gland Acinar Cells, J. Cell Physiol., 177, 1998, p628 - 635
O'Connell, A.C., Lillibridge, C.D., Zheng, C., Baum, B.J., O'Connell, B.C. and Ambudkar, I.S., -Irradiation-Induced Cell Cycle Arrest and Cell Death in a Human Submandibular Gland Cell Line: Effect of E2F1 Expression, J. Cell Physiol, 177, (2), 1998, p264 - 273
O'Connell, B.C., Redman, R.S. and Zheng, C., In Vivo Use of Adenoviral Vectors: Effects on Salivary Gland Structure, Eur. J Morphol., 36, 1998, p55 - 80
Delporte, C., O'Connell, B.C., He, X., Lancaster, H.E., O'Connell, A.C., Agre, P. and Baum, B.J., Increased Fluid Secretion Following Transfer of the Aquaporin-1 cDNA to Irradiated Rat Salivary Glands, Proc. Natl. Acad. Sci. USA 94, 1997, p3268 - 3273
Delporte, C., Panyutin, I.G., Sedelnikova, O.A., Lillibridge, C.D., O'Connell, B.C. and Baum, B.J., Triplex Forming Oligonucleotides Can Modulate Aquaporin-5 Gene Expression in Epithelial cells, Antisense and Nucleic Acid Drug Development, 7, 1997, p523 - 529
Lillibridge, C.D., and O'Connell, B.C., In Human Salivary Cells, Overexpression of E2F1 Overcomes an IFN-- and TNF--Induced Growth Arrest But Does Not Result in Complete Mitosis, J. Cell. Physiol., 172, 1997, p343 - 350
Delporte, C., Miller, G., Kagami, H., Lillibridge, C.D., O'Connell, B.C., Atkinson, J.C. and Baum, B.J., Safety of Salivary Gland-Administered Replication-Deficient Recombinant Adenovirus in Rats, J. Oral Pathol. Med., 27, 1997, p34 - 38
Gene Transfer to Salivary Glands in, Studies in Stomatology and Craniofacial Biology, IOS Press, 1997, pp615 - 631, [O'Connell, B.C. and Baum, B.J.]
Delporte, C., O'Connell, B.C., He, X., Ambudkar, I.S., Agre, P. and Baum, B.J., Adenovirus-mediated Expression of Aquaporin 5 in Epithelial Cells, J. Biol. Chem, 271, (36), 1996, p22070 - 22075
Kagami, H., O'Connell, B.C. and Baum B.J., Evidence for the Systemic Delivery of a Transgene Product from Salivary Glands, Hum. Gene Ther, 7, 1996, p2177 - 2184
Wu, A.J., Chen, Z.J., Tsokos, M., O'Connell, B.C., Ambudkar, I.S. and Baum, B.J., Interferon- induced Cell Death in a Cultured Human Salivary Gland Cell Line, J. Cell Physiol, 167, 1996, p297 - 304
O'Connell, B.C., Xu, T., Walsh, T.J., Sein, T., Mastrangeli, A., Crystal, R.G., Oppenheim, F.G. and Baum, B.J., Transfer of a Gene Encoding the Anticandidal Protein Histatin 3 to Salivary Glands, Hum. Gene Ther, 7, 1996, p2255-
Adesanya, M.R., Redman, R.S., Baum, B.J. and O'Connell, B.C., Acute Inflammatory Response in Adenovirus-mediated Gene Transfer to Rat Salivary Glands, Hum. Gene Ther, 7, (9), 1996, p1085 - 1093
O'Connell, B.C., Ten Hagen, K.G., Lazowski, K.W., Tabak, L.A. and Baum, B.J., Facilitated DNA Transfer to Rat Submandibular Gland in Vivo and GRP Gene Regulation, Am. J. Physiol., 268, 1995, pG1074 - G1078
Sharma, A., O'Connell, B.C., Tabak, L.A. and Bedi, G.S., Expression of a Functional Rat Salivary Cystatin S Polypeptide in Escherichia coli, Arch. Oral. Biol., 40, (7), 1995, p639 - 644
Baum, B.J. and O'Connell, B.C., The Impact of Gene Therapy on Dentistry, JADA, 126, 1995, p179 - 189
Mastrangeli, A.M., O'Connell, B.C., Fox, P.C., Aladib, W., Baum, B.J., and Crystal, R.G., In vivo gene transfer to rat salivary gland, Am. J. Physiol., 266, 1994, pG1146 - G1155
O'Connell, B.C., and Tabak, L.A., A comparison of serine and threonine O-glycosylation by UDPGalNAc: Polypeptide N-acetylgalactosaminyltransferase, J. Dent. Res., 72, 1993, p1554 - 1558
Salivary Gland-Specific Gene Expression in, U.S./Latin American Workshop on Salivary Research, Albuquerque, C&A Press, 1993, pp66 - 75, [O'Connell, B.C. and Tabak, L.A.]
O'Connell, B.C., and Tabak, L.A., Separation of glycopeptides from in vitro O-glycosylation reactions using C18 cartridges, Anal. Biochem., 210, 1993, p423 - 425
O'Connell, B.C., Hagen, F., and Tabak, L.A., The influence of flanking amino acid sequence on O-glycosylation by UDPGalNAc: Polypeptide N-acetylgalactosaminyltransferase, J. Biol. Chem., 267, 1992, p25010 - 25018
O'Connell, B., Tabak, L.A., and Ramasubbu, N., The influence of flanking sequences on O-glycosylation, Biochem. Biophys. Res. Commun., 180, 1991, p1024 - 1024
Non-Peer-Reviewed Publications
Brian O'Connell, The Future Starts Now--a Smart Splint, Eastman Institute of Oral Health Centennial, Rochester, New York, 9 June, 2017, EIOH
Brian O'Connell, The Daily Grind-an Update on the Management of Bruxism, The Greater new York Academy of Prosthodontics, New York, USA, 2 December , 2016, GNYAP
O'Connell, B., Developmental defects of the dentition-diagnosis to management, South-Eastern Branch, PGMDB., Kilkenny, December, 2004
O'Connell, B., Restoration of Endodontically-Treated Teeth-the Evidence, Destination Ireland, University of Minnesota, October, 2004
O'Connell, B., Restorative Dentistry in the Molecular Age, University of Rochester, Annual Alumni Conference, Florida, November, 2003
O'Connell, B., Bioengineering and Restorative Dentistry, International College of Dentists, Annual Conference, Dublin, June, 2003
O'Connell, B., Orthodontic, Periodontic, Prosthodontic-the Interrelationship, European Begg Society of Orthodontics, Annual Conference, Dublin, May, 2003
O'Connell, B., Restoration of Endodontically Treated Teeth, South Eastern Branch, IDA, Scientific Conference, Waterford, 22/2/2002, 2002
O'Connell, B., Restorative Dentistry in the Molecular Age, American Dental Society of Europe, Annual Conference, Prague, June, 2002
O'Connell, B., Functional Genomics, Gordon Research Conference: Saliva and Salivary Glands, Ventura, CA, 16/2/01, 2001
O'Connell, B., Genes and the Prosthodontist, American College of Prosthodontists, Annual Session, New Orleans, 2/11/01, 2001
O'Connell, B., Salivary gland development, regeneration and repair-summary and future directions, 16th International Conference on Oral Biology, Chantilly, Virginia, 12/4/00, 2000
O'Connell, B., Saliva in Health and Disease-Repair and regeneration, Swedish Dental Association, Annual Congress, Stockholm, 27/10/00, 2000
O'Connell, B., Treatment Planning in Prosthodontics, Munster Branch, IDA. Annual Scientific Session, Cork, 22/9/00, 2000
O'Connell, B., Fear of Failure in Prosthodontics, Midland Western Postgraduate Dental Foundation. Annual Meeting, Dromoland Co. Clare, 11-12/2/00, 2000
O'Connell, B., Gene Therapy for Salivary Gland Dysfunction, 5th European Symposium on the Application of Saliva in Clinical Practice and Research, Egmond aan Zee, Netherlands, 20/5/99, 1999
O'Connell, B., Viral-mediated Gene Transfer to the Salivary Glands, University of Manchester, Biological Sciences-Physiology section, 15/12/99, 1999
O'Connell, B., Recent Developments in Clinical Research on Saliva, International Association for Dental Research. Annual Session, Vancouver, 12/3/99, 1999
O'Connell, B., Gene Transfer Technology and the Oral Cavity, Latin American Association for Salivary Research, 3rd International Meeting, Vina del Mar, Chile, 15/11/99, 1999
O'Connell, B., Gene Transfer and Gene Therapy, Oral Biology at the Turn of the Century: Misconceptions, Truths, Challenges and Prospects, Interlaken, Switzerland, 20/8/98, 1998, European Research Group for Oral Biology
O'Connell, B., Advances in Gene Therapy, FDI, 86th Annual World Dental Congress; Scientific Frontiers in Clinical Dentistry, Barcelona, Spain, 9/10/98, 1998
O'Connell, B., Genetic Regulation and Gene Expression of Salivary Proteins, U.S.-China Workshop on the Role of Saliva in Oral Health, Beijing, 19/10/98, 1998
O'Connell, B., Salivary Gland Specific Gene Expression-In vivo Gene Transfer as a Tool, Gordon Research Conference: Saliva and Salivary Glands, Ventura, CA, 25/2/97, 1997
O'Connell, B., Use of in Vivo Gene Transfer for the Study of Salivary Gland Function, 2nd Stenone Symposium, Cagliari, Italy, 24/5/97, 1997
O'Connell, B., Prospects for Salivary Gland Gene Therapy, Graduate Student Seminar, University of Rochester, New York, 29/4/97, 1997
O'Connell, B., Gene Transfer; How to Teach an Old Gland New Tricks, International Association for Dental Research, Annual Session, Orlando, 21/3/97, 1997
O'Connell, B., DNA as a Therapeutic Agent for Oral Disease, University of Texas Health Science Center, San Antonio, 21/5/96, 1996
O'Connell, B., Therapeutic Interventions: Gene Transfer to Salivary Glands, Salivary Gland Biogenesis and Function, Airlie, Virginia, 10/11/96, 1996
O'Connell, B., Gene-based Approaches to the Treatment of Oral Disease, Scientific Frontiers in Dentistry Symposium, Bethesda, 14/6/96, 1996
O'Connell, B., Gene Therapy and Oral Diseases, Academy of Prosthodontics, Annual Meeting, Tucson, 19/5/95, 1995
O'Connell, B., An Integrated Approach to Salivary Gland Repair (Symposium, Plenary lecture). Salivary Gland Gene Therapy (Lunch and Learning), American Association for Dental Research, Annual Session, San Antonio, 10-11/3/95, 1995
O'Connell, B., Gene Therapeutics: Supportive Therapies for Cancer Patients, International Society for Oral Oncology, 9th Annual Meeting, Bethesda, 3/6/94, 1994
O'Connell, B., Overview of Gene Therapy (Lecture). Salivary Gland Gene Therapy (Seminar), University of Minnesota, Minneapolis, 6-7/10/94, 1994
O'Connell, B., Salivary Gland Gene Therapy, University of Alabama, Birmingham, 1/8/94, 1994
O'Connell, B., Adenovirus-Mediated Gene Transfer to the Salivary Glands, Forsyth Dental Center, Boston, 15/7/93, 1993
Research Expertise
Projects
- Title
- Investigative and Therapeutic Gene Transfer to the Salivary Glands
- Funding Agency
- NIH Grant-NIDCR Project Z01-DE00675-01-03
- Date From
- 1996
- Date To
- 1999
- Title
- Construction of Adenovirus Vectors for the Study of Gene Control and Protein Function
- Summary
- Funding Agency
- NIH-NIDCR Research and Development Contract.
- Date From
- 6/97
- Date To
- 5/00
- Title
- Production and Testing of Adenovirus Vectors for Clinical Use
- Funding Agency
- NIH-NIDCR Research and Development Contract.
- Date From
- 6/97
- Date To
- 5/99
- Title
- Provost Award
- Funding Agency
- Trinity College Dublin
- Date From
- 1999
- Date To
- 1999
- Title
- In vivo function and regulation of salivary antimicrobial proteins
- Summary
- Funding Agency
- Health Research Board-Project Grant.
- Date From
- 2000
- Date To
- 2003
- Title
- Real Time PCR equipment
- Funding Agency
- Health Research Board-Co-investigator for equipment grant.
- Date From
- 2000
- Date To
- 2000
- Title
- Antifungal Mechanism of Human Salivary Histatin
- Funding Agency
- Health Research Board-Project Grant
- Date From
- 2002
- Title
- Mechanobiology of Tissue Engineering
- Summary
- Theme Co-ordinator. Trinity Centre for Bioengineering (TCBE)
- Funding Agency
- Higher Education Authority-PRTLI
- Date From
- 2002
- Date To
- 2007
- Title
- Regulation of Salivary Gland Gene Expression
- Funding Agency
- Wellcome Trust-Travelling Fellowship
- Date From
- 2003
- Date To
- 2005
- Title
- Cells Under Strain
- Summary
- Project leader, Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN)
- Funding Agency
- Science Foundation Ireland (SFI)
- Date From
- 2004
- Title
- Differential cellular response to nanoscale engineered titanium surfaces
- Summary
- Co-Principal Investigator
- Date From
- 2005
- Date To
- 2009
- Title
- SMART SPLINT
- Summary
- Superior monitoring & analysis relayed through sensors providing longitudinal information on nocturnal tooth grinding
- Funding Agency
- Enterprise Ireland
- Date From
- October 2008
- Date To
- October 2009
Recognition
Representations
Journal of Dental Research (Editorial Board)
Antimicrobial Agents and Chemotherapy (Reviewer)
Critical Reviews in Oral Biology and Medicine (Reviewer)
American Heart Association (Grant reviewer)
Anatomical Record (Reviewer)
Archives of Oral Biology (Reviewer)
International Journal of Cancer (Reviewer)
Oral Bioscience and Medicine (Editorial Board)
Oral Diseases (Editorial Board)
Awards and Honours
Fellow, American College of Prosthodontists
Fellow, Trinity College, Dublin
College Scholar (U.C.C.)
Edward Gurr Prize (U.C.C.)
U.C.C. Scholarship
Gold Medal Restorative Dentistry (U.C.C.)
Peel Memorial Award (U.C.C.)
Bloor Award (U. Rochester) (First Place Biochemistry Doctorate)
NIDR Travel Award
AADR/IADR Hatton Award, First Place, (International Young Investigator)
Memberships
International Association for Dental Research
American Association for the Advancement of Science
American Society for Biochemistry and Molecular Biology
Fellow of the American College of Prosthodontists