Biochemistry - Modules

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Junior Sophister - Modules

  • Genomics and Systems Biology

This module will introduce students to core concepts of genomics and systems biology.

Topics discussed will include structural genomics and genome sequencing; DNA sequencing methods and the story of the human genome project; genome annotation and gene finding; comparative genomics; functional genomics; epigenomics; transcriptomics; regulatory networks; and the cis-regulatory code.

Furthermore, students will be introduced to the use of genomics techniques in medicine and will learn about methods used to analyse the proteome of an organism.

  • Cell Physiology and Pharmacology

The lectures in this module focus on (i) membrane structure, proteins and properties; (ii) receptors and neurotransmitters, (iii) the principles of drug action, drug development and drug targets.

The module is designed to consider the structure of the membrane, the changes that occur in the membrane under different biological circumstances using age as an example, and role of membrane proteins. Cell functions, for example, the control of intracellular calcium by cells and transmitter release will be considered in the context of the membrane proteins that impact on these functions. There is a problem-based learning element to this course that will be a team-based exercise.

An overall theme will be chosen and groups of 3 or 4 students will be assigned specific aspects of the theme. The objective
is to undertake research on the theme and prepare a presentation that is cohesive across
the topic. Each team member will contribute to the presentation.

  • Introduction to Immunology & Immunometabolism (S2)

This module introduces to the basic components and function of the immune system – the molecules, cells, tissues and organs that make up the immune system. It will illustrate the immune responses to infection. Additionally, it will introduce students to the importance of central energy and intermediary metabolic pathways or bioenergetics before considering how they are dysregulated in diseases like cancer and also how we can harness this knowledge for new immunotherapies.

For further information on course modules visit: www.tcd.ie/science/undergraduate/tr060-biological-and-biomedical-science/junior-sophister