Dr. Peter Lavin
Clinical Associate Professor, Clinical Medicine
Biography
Dr. Lavin is Consultant Nephrologist and General Internal Medicine Physician in Tallaght University Hospital. He is also a Clinical Senior Lecturer in Clinical Medicine in Trinity College Dublin.
He graduated from the Royal College of Surgeons in Ireland in 1998. He continued postgraduate training in Ireland in Internal Medicine and Nephrology, before completing a Nephrology Fellowship in Duke University Medical Center, NC, USA. He also worked in the Duke University Center for Human Genetics (2006-2011) where he researched autosomal dominant hereditary kidney disease (FSGS, C3 glomerulopathy and Interstitial Nephritis) using molecular genetics techniques.
He returned to Ireland to practice as a Nephrologist at Tallaght Hospital in 2011 where his clinical interests are Familial Kidney Disease, Diabetic Kidney Disease, Glomerular Kidney Disease, C3 Glomerulopathy, Acute Kidney Injury and Intensive Care Nephrology.
Publications and Further Research Outputs
Peer-Reviewed Publications
Connaughton DM, Kennedy C, Shril S, Mann N, Murray SL, Williams PA, Conlon E, Nakayama M, van der Ven AT, Itself H, Kause F, Kolvenbach CM, Dai R, Vivante A, Braun DA, Schneider R, Kitzler TM, Moloney B, Moran CP, Smyth JS, Kennedy A, Benson K, Stapleton C, Denton M, Magee C, O'Seaghdha CM, Plant WD, Griffin MD, Awan A, Sweeney C, Mane SM, Lifton RP, Griffin B, Leavey S, Casserly L, de Freitas DG, Holian J, Dorman A, Doyle B, Lavin PJ, Little MA. Conlon PJ, Hildebrandt F., Monogenic causes of chronic kidney disease in adults, Kidney International, 95, (4), 2019, p914 - 928
Kennedy C, Connaughton DM, Murray S, Ormond J, Butler A, Phelan E, Young J, Durack L, Flavin J, O'Grady M, O'Kelly P, Lavin P, Leavey S, Lappin D, Giblin L, Casserly L, Plant WD, Conlon PJ, Home haemodialysis in Ireland, QJM: An International Journal of Medicine, 111, (4), 2018, p225 - 229
Zivná M, Kidd K, Přistoupilová A, Bare ová V, DeFelice M, Blumenstiel B, Harden M, Conlon P, Lavin P, Connaughton DM, Hartmannová H, Hodaňová K, Stránecký V, Vrbacká A, Vyleťal P, ivný J, Votruba M, Sovová J, Hůlková H, Robins V, Perry R, Wenzel A, Beck BB, Seeman T, Viklický O, Rajnochová-Bloudíčková S, Papagregoriou G, Deltas CC, Alper SL, Greka A, Bleyer AJ, Kmoch S, Noninvasive Immunohistochemical Diagnosis and Novel MUC1 Mutations Causing Autosomal Dominant Tubulointerstitial Kidney Disease., Journal of the American Society of Nephrology, 29, 2018
Corrigan C, Peterson L, McVeigh C, Lavin PJ, Mellotte GJ, Wall C, Baker Kerrigan A, Barnes L, O'Neill D, Moss H, The Perception of Art among Patients and Staff on a Renal Dialysis Unit, Ir Med J, 110, (9), 2017, pP633
O'Shaughnessy M, Allen N, Davin D, Mentre L, O'Regan J, Payne Danson E, Lavin P, Grimes T , Agreement Between Renal Prescribing References and Determination of Prescribing Appropriateness in Hospitalised Patients with Chronic Kidney Disease, QJM An International Journal of Medicine, 2017
Gunning H, Taylor G, Smyth A, Mellotte G, Fennell J, Murphy P, Lavin P, Wall C, An Approach to Optimise Therapeutic Vancomycin Dosage in a Haemodialysis Population., Irish Medical Journal, 109, (9), 2016, p465-
Wong L, Moran S, Lavin PJ, Dorman AM, Conlon PJ, Kidney transplant outcomes in familial C3 glomerulopathy, Clinical Kidney Journal, 9, (3), 2016, p403 - 407
Connaughton DM, Bukhari S, Conlon P, Cassidy E, O'Toole M, Mohamad M, Flanagan J, Butler T, O'Leary A, Wong L, O'Regan J, Moran S, O'Kelly P, Logan V, Griffin B, Griffin M, Lavin P, Little MA, Conlon P., The Irish Kidney Gene Project, Nephron, 130, (4), 2015, p293 - 301
Wong L, Kok HK, Akib RR, Lavin PJ, Torreggiani WC., An unusual cause for loin pain., Kidney International, 88, (3), 2015, p644 - 644
Hall G, Gbadegesin RA, Lavin P, Wu G, Liu Y, Oh EC, Wang L, Spurney RF, Eckel J, Lindsey T, Homstad A, Malone AF, Phelan PJ, Shaw A, Howell DN, Conlon PJ, Katsanis N, Winn MP, A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS, Journal of the American Society of Nephrology, 26, (4), 2015, p831 - 843
Gbadegesin RA, Hall G, Adeyemo A, Hanke N, Tossidou I, Burchette J, Wu G, Homstad A, Sparks MA, Gomez J, Jiang R, Alonso A, Lavin P, Conlon P, Korstanje R, Stander MC, Shamsan G, Barua M, Spurney R, Singhal PC, Kopp JB, Haller H, Howell D, Pollak MR, Shaw AS, Schiffer M, Winn MP, Mutations in the Gene That Encodes the F-Actin Binding Protein Anillin Cause FSGS., Journal of the American Society of Nephrology : JASN, 2014
Hall G, Rowell J, Farinelli F, Gbadegesin RA, Lavin P, Wu G, Homstad A, Malone A, Lindsey T, Jiang R, Spurney R, Tomaselli GF, Kass DA, Winn MP, Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity., American journal of physiology. Renal physiology, 306, (12), 2014, pF1442-50
O'Shaughnessy MM, O'Regan JA, Lavin P, Prevention of Sudden Cardiac Death in Hemodialysis Patients., Cardiovascular & hematological disorders drug targets, 2014
Pickering MC, D'Agati VD, Nester CM, Smith RJ, Haas M, Appel GB, Alpers CE, Bajema IM, Bedrosian C, Braun M, Doyle M, Fakhouri F, Fervenza FC, Fogo AB, Frémeaux-Bacchi V, Gale DP, Goicoechea de Jorge E, Griffin G, Harris CL, Holers VM, Johnson S, Lavin PJ, Medjeral-Thomas N, Paul Morgan B, Nast CC, Noel LH, Peters DK, Rodríguez de Córdoba S, Servais A, Sethi S, Song WC, Tamburini P, Thurman JM, Zavros M, Cook HT, C3 glomerulopathy: consensus report., Kidney international, 2013
Gbadegesin RA, Brophy PD, Adeyemo A, Hall G, Gupta IR, Hains D, Bartkowiak B, Rabinovich CE, Chandrasekharappa S, Homstad A, Westreich K, Wu G, Liu Y, Holanda D, Clarke J, Lavin P, Selim A, Miller S, Wiener JS, Ross SS, Foreman J, Rotimi C, Winn MP, TNXB mutations can cause vesicoureteral reflux., Journal of the American Society of Nephrology : JASN, 24, (8), 2013, p1313-22
Gbadegesin RA, Lavin PJ, Hall G, Bartkowiak B, Homstad A, Jiang R, Wu G, Byrd A, Lynn K, Wolfish N, Ottati C, Stevens P, Howell D, Conlon P, Winn MP, Inverted formin 2 mutations with variable expression in patients with sporadic and hereditary focal and segmental glomerulosclerosis., Kidney international, 81, (1), 2012, p94-9
Malik TH, Lavin PJ, Goicoechea de Jorge E, Vernon KA, Rose KL, Patel MP, de Leeuw M, Neary JJ, Conlon PJ, Winn MP, Pickering MC, A hybrid CFHR3-1 gene causes familial C3 glomerulopathy, Journal of the American Society of Nephrology, 23, (7), 2012, p1155 - 1160
Luo X, Hall G, Li S, Bird A, Lavin PJ, Winn MP, Kemper AR, Brown TT, Koeberl DD, Hepatorenal correction in murine glycogen storage disease type I with a double-stranded adeno-associated virus vector., Molecular therapy : the journal of the American Society of Gene Therapy, 19, (11), 2011, p1961-70
LAVIN PJ, WINN MP., TORCing up the importance of calcium signaling., Journal of the American Society of Nephrology, 22, (8), 2011, p1391 - 1393
G Hall, J Eckel, P Lavin, R Gbadegesin, G Wu, MP Winn, DEFINING THE TRANSCRIPTIONAL REGULATION OF ANGIOTENSIN II-INDUCED TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, TYPE 6 EXPRESSION IN MURINE PODOCYTES, JOURNAL OF INVESTIGATIVE MEDICINE, 12. American Federation for Medical Research, Southern Regional Meeting , New Orelans, 2011, 59, (2), 2011, pp498 - 499
Gbadegesin R, Lavin P, Foreman J, Winn M, Pathogenesis and therapy of focal segmental glomerulosclerosis: an update., Pediatric nephrology (Berlin, Germany), 26, (7), 2011, p1001-15
Akilesh S, Suleiman H, Yu H, Stander MC, Lavin P, Gbadegesin R, Antignac C, Pollak M, Kopp JB, Winn MP, Shaw AS, Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis., The Journal of clinical investigation, 121, (10), 2011, p4127-37
Eckel J, Lavin PJ, Finch EA, Mukerji N, Burch J, Gbadegesin R, Wu G, Bowling B, Byrd A, Hall G, Sparks M, Zhang ZS, Homstad A, Barisoni L, Birbaumer L, Rosenberg P, Winn MP, TRPC6 enhances angiotensin II-induced albuminuria., Journal of the American Society of Nephrology : JASN, 22, (3), 2011, p526-35
Gbadegesin R, Lavin P, Janssens L, Bartkowiak B, Homstad A, Wu G, Bowling B, Eckel J, Potocky C, Abbott D, Conlon P, Scott WK, Howell D, Hauser E, Winn MP, A new locus for familial FSGS on chromosome 2p., Journal of the American Society of Nephrology : JASN, 21, (8), 2010, p1390-7
O'Seaghdha CM, McQuillan R, Moran AM, Lavin P, Dorman A, O'Kelly P, Mohan DM, Little P, Hickey DP, Conlon PJ, Higher tacrolimus trough levels on days 2-5 post-renal transplant are associated with reduced rates of acute rejection., Clinical transplantation, 23, (4), 2009, p462-8
Gbadegesin R, Bartkowiak B, Lavin PJ, Mukerji N, Wu G, Bowling B, Eckel J, Damodaran T, Winn MP, Exclusion of homozygous PLCE1 (NPHS3) mutations in 69 families with idiopathic and hereditary FSGS., Pediatric nephrology (Berlin, Germany), 24, (2), 2009, p281-5
Lavin PJ, Gbadegesin R, Damodaran TV, Winn MP, Therapeutic Targets in FSGS, Current Opinion in Nephrology and Hypertension, 17, (4), 2008, p386 - 392
Lavin PJ, Laing ME, O'Kelly P, Moloney FJ, Gopinathan D, Aradi AA, Shields DC, Murphy GM, Conlon PJ, Improved renal allograft survival with vitamin D receptor polymorphism., Renal failure, 29, (7), 2007, p785-9
Malone A, McConkey S, Dorman A, Lavin P, Gopthanian D, Conlon P, Mycobacterium tuberculosis in a renal transplant transmitted from the donor., Irish journal of medical science, 176, (3), 2007, p233-5
Ryan JG, Morgan RK, Lavin PJ, Murray FE, O'Connell PG, Current management of corticosteroid-induced osteoporosis: variations in awareness and management., Irish journal of medical science, 173, (1), 2005, p20-2
Research Expertise
Recognition
Representations
Clinical Director, Medical Directorate Tallaght University Hospital
Clinical Lead in Nephrology, Tallaght University Hospital
Regional Lead for Dublin Milands Hospital Group in Nephrology
Honorary Secretary Irish Nephrology Society
Member of National Renal Intelligence Advisory Group
Chairman, Joint Tallaght Hospital and St James's Hospital Research Ethics Committee
Member of Joint Tallaght Hospital and St James's Hospital Research Ethics Committee
Member on Nephrology Specialist Training Committee (STC), Royal College of Physicians in Ireland
Awards and Honours
Henry Christian Award - American Federation of Medical Research
Memberships
Irish Nephrology Society
American Society of Nephrology
Fellowship of the Royal College of Physicians in Ireland
Membership of Royal College of Physicians in Ireland