Publications

JOURNAL PUBLICATIONS

VIEW MOST RECENT PUBLICATIONS ON GOOGLE SCHOLAR 

2023: 

1. R Burdis, X Barceló, DJ Kelly. Temporal enzymatic treatment to enhance the remodelling of multiple cartilage microtissues into a structurally organised tissue. Advanced HealthCare Materials
2. P Gierlich, C Donohoe, K Behan, DJ Kelly, MO Senge, LC Gomes-da-Silva. Antitumor Immunity Mediated by Photodynamic Therapy Using Injectable Chitosan Hydrogels for Intratumoral and Sustained Drug Delivery. Biomacromolecules
3. F Chariyev-Prinz, N Neto, MG Monaghan, DJ Kelly. Time-Dependent Anabolic Response of hMSC-Derived Cartilage Grafts to Hydrostatic Pressure. Journal of Tissue Engineering and Regenerative Medicine
4. IT Whelan, R Burdis, S Shahreza, E Moeendarbary, DA Hoey, DJ Kelly. A microphysiological model of bone development and regeneration. Biofabrication 15 (3), 034103, 2023.
5. F Chariyev-Prinz, A Szojka, N Neto, R Burdis, MG Monaghan, DJ Kelly. An assessment of the response of human MSCs to hydrostatic pressure in environments supportive of differential chondrogenesis. Journal of Biomechanics 154, 111590, 2023.
6. Selcan Guler, Kian Eichholz, Farhad Chariyev-Prinz, Pierluca Pitacco, Halil Murat Aydin, Daniel J Kelly, İbrahim Vargel. Biofabrication of Poly (glycerol sebacate) Scaffolds Functionalized with a Decellularized Bone Extracellular Matrix for Bone Tissue Engineering. Bioengineering, 10, 1, 30, 2023.
7. B Wang, X Barceló, S Von Euw, DJ Kelly. 3D printing of mechanically functional meniscal tissue equivalents using high concentration extracellular matrix inks. Materials Today Bio 20, 100624, 2023.
8. FE Freeman, P Dosta, LC Shanley, N Ramirez Tamez, CJ Riojas Javelly, O Mahon, DJ Kelly, N Artzi. Localized Nanoparticle‐Mediated Delivery of miR‐29b Normalizes the Dysregulation of Bone Homeostasis Caused by Osteosarcoma whilst Simultaneously Inhibiting Tumor Growth. Advanced Materials 35 (23), 2207877, 2023.
9. X Barceló, O Garcia, DJ Kelly. Chondroitinase ABC Treatment Improves the Organization and Mechanics of 3D Bioprinted Meniscal Tissue. ACS Biomaterials Science & Engineering (in press).
10. LC Shanley, OR Mahon, SA O'Rourke, NGB Neto, MG Monaghan, DJ Kelly, Dunne A. Macrophage metabolic profile is altered by hydroxyapatite particle size. Acta Biomaterialia 160, 311-321, 2023.
11. R Burdis, GS Kronemberger, DJ Kelly. Engineering High-Quality Cartilage Microtissues Using Hydrocortisone Functionalized Microwells. Tissue Engineering Part C: Methods 29 (4), 121-133, 2023.
12. X Barceló, KF Eichholz, IF Gonçalves, O Garcia, DJ Kelly. Bioprinting of structurally organized meniscal tissue within anisotropic melt electrowritten scaffolds. Acta Biomaterialia 158, 216-227, 2023.

 

2022:

13. Tanya J Levingstone, Eamon J Sheehy, Conor J Moran, Gráinne M Cunniffe, Pedro J Diaz Payno, Robert T Brady, Henrique V Almeida, Simon F Carroll, John M O’Byrne, Daniel J Kelly, Pieter AJ Brama, Fergal J O’Brien. Evaluation of a co-culture of rapidly isolated chondrocytes and stem cells seeded on tri-layered collagen-based scaffolds in a caprine osteochondral defect model. Biomaterials and Biosystems, 8, 100066, 2022.
14. Leandra Santos Baptista, Constance Porrini, Gabriela Soares Kronemberger, Daniel John Kelly, Cecile M Perrault. 3D organ-on-a-chip: The convergence of microphysiological systems and organoids. Frontiers in Cell and Developmental Biology 10:1043117, 2022.
15. Browe DC, Burdis R, Díaz-Payno PJ, Freeman FE, Nulty JM, Buckley CT, Brama PAJ, Kelly DJ. Promoting endogenous articular cartilage regeneration using extracellular matrix scaffolds. Mater Today Bio. 2022 Jul 5;16:100343.
16. Burdis R, Chariyev-Prinz F, Browe DC, Freeman FE, Nulty J, McDonnell EE, Eichholz KF, Wang B, Brama P, Kelly DJ. Spatial patterning of phenotypically distinct microtissues to engineer osteochondral grafts for biological joint resurfacing. Biomaterials. 2022 Aug 28;289:121750.
17. Kian F. Eichholz, Inês Gonçalves, Xavier Barceló, Angelica S. Federici, David A. Hoey, Daniel J. Kelly. How to design, develop and build a fully-integrated melt electrowriting 3D printer. Additive Manufacturing, Volume 58, 2022, 102998,
18. Eichholz KF, Freeman FE, Pitacco P, Nulty J, Ahern D, Burdis R, Browe DC, Garcia O, Hoey DA, Kelly DJ. Scaffold microarchitecture regulates angiogenesis and the regeneration of large bone defects. Biofabrication. 2022 Aug 31;14(4).
19. Merrild NG, Holzmann V, Ariosa-Morejon Y, Faull PA, Coleman J, Barrell WB, Young G, Fischer R, Kelly DJ, Addison O, Vincent TL, Grigoriadis AE, Gentleman E. Local depletion of proteoglycans mediates cartilage tissue repair in an ex vivo integration model. Acta Biomater. 2022 Sep 1;149:179-188.
20. Pierluca Pitacco, Joanna M. Sadowska, Fergal J. O'Brien, Daniel J. Kelly. 3D bioprinting of cartilaginous templates for large bone defect healing. Acta Biomaterialia, 156, 61-74, 2023.
21. R Paetzold, FB Coulter, G Singh, DJ Kelly, ED O'Cearbhaill. Fused filament fabrication of polycaprolactone bioscaffolds: Influence of fabrication parameters and thermal environment on geometric fidelity and mechanical properties. Bioprinting 27, e00206.
22. Barceló, X.; Eichholz, K.F.; Garcia, O.; Kelly, D.J. Tuning the Degradation Rate of Alginate-Based Bioinks for Bioprinting Functional Cartilage Tissue. Biomedicines 2022, 10, 1621
23. Browe DC, Díaz-Payno PJ, Freeman FE, Schipani R, Burdis R, Ahern DP, Nulty JM, Guler S, Randall LD, Buckley CT, Brama PAJ, Kelly DJ. Bilayered extracellular matrix derived scaffolds with anisotropic pore architecture guide tissue organization during osteochondral defect repair. Acta Biomater. 2022 Apr 15;143:266-281
24. A Dufour, XB Gallostra, C O'Keeffe, K Eichholz, S Von Euw, O Garcia, DJ Kelly. Integrating melt electrowriting and inkjet bioprinting for engineering structurally organized articular cartilage. Biomaterials 283, 121405, 2022.
25. PJ Diaz-Payno, D Browe, FE Freeman, J Nulty, R Burdis, DJ Kelly. GREM1 suppresses hypertrophy of engineered cartilage in vitro but not bone formation in vivo. Tissue Engineering (in press).
26. DC Browe, PJ Díaz-Payno, FE Freeman, R Schipani, R Burdis, DP Ahern, P Brama, C.T. Buckley, DJ Kelly. Bilayered Extracellular Matrix Derived Scaffolds with Anisotropic Pore Architecture Guide Tissue Organization During Osteochondral Defect Repair. Acta Biomaterialia (in press).
27. P Aprile, IT Whelan, BN Sathy, SF Carroll, DJ Kelly. Soft Hydrogel Environments that Facilitate Cell Spreading and Aggregation Preferentially Support Chondrogenesis of Adult Stem Cells. Macromolecular Bioscience, 2100365, 2022.
28. K Behan, A Dufour, O Garcia, D Kelly. Methacrylated Cartilage ECM-Based Hydrogels as Injectables and Bioinks for Cartilage Tissue Engineering. Biomolecules 12 (2), 216, 2022.
29. B Wang, F Chariyev-Prinz, R Burdis, K Eichholz, DJ Kelly. Additive manufacturing of cartilage-mimetic scaffolds as off-the-shelf implants for joint regeneration. Biofabrication 14 (2), 024101, 2022.

 

2021:

30. R Burdis, F Chariyev-Prinz, DJ Kelly. Bioprinting of biomimetic self-organised cartilage with a supporting joint fixation device. Biofabrication 14 (1), 015008, 2021.
31. Yu Shrike Zhang, Ghazaleh Haghiashtiani, Tania Hübscher, Daniel J Kelly, Jia Min Lee, Matthias Lutolf, Michael C McAlpine, Wai Yee Yeong, Marcy Zenobi-Wong, Jos Malda. 3D extrusion bioprinting. Nature Reviews Methods Primers 1 (1), 1-20, 2021.
32. H Pauly, K Fischenich, D Kelly, K Popat, J Easley, RH Palmer, TL Haut Donahue. The Effect of Anterior Cruciate Ligament Reconstruction with an Electropsun Scaffold on Tibiofemoral Contact Mechanics. Annals of Biomedical Engineering, 1-12, 2021.
33. FE Freeman, R Burdis, OR Mahon, DJ Kelly, N Artzi. A Spheroid Model of Early and Late‐Stage Osteosarcoma Mimicking the Divergent Relationship between Tumor Elimination and Bone Regeneration. Advanced Healthcare Materials, 2101296, 2021.
34. B Wang, PJ Díaz-Payno, DC Browe, FE Freeman, J Nulty, R Burdis, DJ Kelly. Affinity-bound growth factor within sulfated interpenetrating network bioinks for bioprinting cartilaginous tissues. Acta Biomaterialia 128, 130-142, 2021.
35. AM McDermott, EA Eastburn, DJ Kelly, JD Boerckel. Effects of chondrogenic priming duration on mechanoregulation of engineered cartilage. Journal of Biomechanics, 110580, 2021.
36. J Nulty, R Burdis, DJ Kelly. Biofabrication of Prevascularised Hypertrophic Cartilage Microtissues for Bone Tissue Engineering. Frontiers in Bioengineering and Biotechnology 9, 469, 2021.
37. FE Freeman, R Burdis, DJ Kelly. Printing New Bones: From Print-and-Implant Devices to Bioprinted Bone Organ Precursors, Trends in Molecular Medicine, 2021.
38. I Whelan, E Moeendarbary, D Hoey, DJ Kelly. Biofabrication of vasculature in microphysiological models of bone. Biofabrication, 13, 032004, 2021.
39. OR Mahon, DC Browe, PJ Diaz-Payno, P Pitacco, KT Cunningham, A Dunne, DJ Kelly. Extracellular matrix scaffolds derived from different musculoskeletal tissues drive distinct macrophage phenotypes and direct tissue-specific cellular differentiation. Journal of Immunology and Regenerative Medicine 12, 100041, 2021.
40. J Nulty, FE Freeman, DC Browe, R Burdis, DP Ahern, P Pitacco, YB Lee, E Alsberg, DJ Kelly. 3D bioprinting of prevascularised implants for the repair of critically-sized bone defects. Acta Biomaterialia 126, 154-169, 2021.
41. R Burdis, DJ Kelly. Biofabrication and bioprinting using cellular aggregates, microtissues and organoids for the engineering of musculoskeletal tissues. Acta Biomaterialia 126, 1-14, 2021.
42. JM Sadowska, KJ Genoud, DJ Kelly, FJ O'Brien. Bone biomaterials for overcoming antimicrobial resistance: Advances in non-antibiotic antimicrobial approaches for regeneration of infected osseous tissue. Materials Today, 46, 136-154, 2021.
43. LC Shanley, OR Mahon, DJ Kelly, A Dunne. Harnessing the innate and adaptive immune system for tissue repair and regeneration: Considering more than macrophages. Acta Biomaterialia , 133, 208-221, 2021.
44. SF Carroll, CT Buckley, DJ Kelly. Measuring and Modeling Oxygen Transport and Consumption in 3D Hydrogels Containing Chondrocytes and Stem Cells of Different Tissue Origins. Frontiers in Bioengineering and Biotechnology, 9: 591126, 2021.

 

2020:

45. R Sridharan, DJ Kelly, FJ O'Brien. Substrate Stiffness Modulates the Crosstalk Between Mesenchymal Stem Cells and Macrophages. Journal of Biomechanical Engineering 143 (3), 2021.
46. Aprile, P., Kelly, DJ. Hydrostatic pressure regulates the volume, aggregation and chondrogenic differentiation of bone marrow derived stromal cells Frontiers in Bioengineering and Biotechnology 8, 1526, 2020.
47. KF Eichholz, S Von Euw, R Burdis, DJ Kelly, DA Hoey. Development of a New Bone‐Mimetic Surface Treatment Platform: Nanoneedle Hydroxyapatite (nnHA) Coating. Advanced Healthcare Materials, 2001102, 2020.
48. R Sridharan, KJ Genoud, DJ Kelly, FJ O’Brien. Hydroxyapatite Particle Shape and Size Influence MSC Osteogenesis by Directing the Macrophage Phenotype in Collagen-Hydroxyapatite Scaffolds. ACS Applied Bio Materials 3 (11), 7562-7574, 2020.
49. Pedro J Gouveia, Tom Hodgkinson, Isabel Amado, Joanna M Sadowska, Alan J Ryan, Sara Romanazzo, Simon Carroll, Sally-Ann Cryan, Daniel J Kelly, Fergal J O'Brien. Development of collagen-poly (caprolactone)-based core-shell scaffolds supplemented with proteoglycans and glycosaminoglycans for ligament repair. Materials Science and Engineering: C , 111657, 2020.
50. Freeman, F., Pitacco, P., van Dommelen, L., Nulty, J., Browe, D.C., Shin, J-Y., Alsberg, E., Kelly, D.J. 3D bioprinting spatiotemporally defined patterns of growth factors to tightly control tissue regeneration. Sciences Advances, 6 (33), eabb5093, 2020.
51. M Lemoine, SM Casey, JM O'Byrne, DJ Kelly, FJ O'Brien. The development of natural polymer scaffold-based therapeutics for osteochondral repair. Biochemical Society Transactions 48 (4), 1433-1445.
52. Stanislas Von Euw, Thierry Azaïs, Viacheslav Manichev, Guillaume Laurent, Gérard Pehau-Arnaudet, Margarita Rivers, Nagarajan Murali, Daniel J Kelly, Paul G Falkowski. Solid-state phase transformation and self-assembly of amorphous nanoparticles into higher-order mineral structures. Journal of the American Chemical Society 142 (29), 12811-12825, 2020.
53. Olvera, D., Sathy, B., Kelly, D.J. Spatial presentation of tissue-specific extracellular matrix components along electrospun scaffolds for tissue engineering the bone-ligament interface. ACS Biomaterials Science & Engineering, 6 (9), 5145-5161, 2020.
54. Critchley, S. Sheehy, E.J., Cunniffe, G., Diaz-Payno, Carroll, S., Oju, J., Eben., A., Brama, P., Kelly, D.J. 3D printing of fibre-reinforced cartilaginous templates for the regeneration of osteochondral defects. Acta Biomaterilia, 113, 130-143, 2020.
55. J. Diaz-Payno, D.C. Browe, G.M. Cunniffe, Daniel J. Kelly. The identification of articular cartilage and growth plate extracellular matrix-specific proteins supportive of either osteogenesis or stable chondrogenesis of stem cells. Biochemical and Biophysical Research Communications, 528 (2), 285-291, 2020.
56. Schipani R, Scheurer S, Florentin R, Critchley SE, Kelly DJ. Reinforcing interpenetrating network hydrogels with 3D printed polymer networks to engineer cartilage mimetic composites. 12;12(3):035011, 2020.
57. Freeman, F.E., Brennan, M.Á., Browe, D.C., Kelly, D.J. McNamara, L.M., Layrolle, P.A Developmental Engineering-Based Approach to Bone Repair: Endochondral Priming Enhances Vascularization and New Bone Formation in a Critical Size Defect. Frontiers in Bioengineering and Biotechnology 8,230, 2020.
58. Westin, C.B., Nagahara, M.H.T., Decarli, M.C., Kelly, D.J., Moraes, Â.M. Development and characterization of carbohydrate-based thermosensitive hydrogels for cartilage tissue engineering. European Polymer Journal, 129,109637, 2020.
59. Olwyn R Mahon, David C Browe, Tomas Gonzalez-Fernandez, Pierluca Pitacco, Ian T Whelan, Stanislas Von Euw, Christopher Hobbs, Valeria Nicolosi, Kyle T Cunningham, Kingston HG Mills, Daniel J Kelly, Aisling Dunne. Nano-particle mediated M2 macrophage polarization enhances bone formation and MSC osteogenesis in an IL-10 dependent manner. Biomaterials 239, 119833, 2020.
60. R Schipani, D Nolan, C Lally, DJ Kelly. Integrating Finite Element Modelling and 3D Printing to Engineer Biomimetic Polymeric Scaffolds for Tissue Engineering. Connective Tissue Research 61(2):174-189, 2020.

 

2019:

61. F Freeman, D Browe, J Nulty, S Von Euw, W Grayson, DJ Kelly. Biofabrication of multiscale bone extracellular matrix scaffolds for bone tissue engineering. e Cells and Materials, 38, 168-187, 2019.
62. AM McDermott, S Herberg, DE Mason, JM Collins, HB Pearson, JH Dawahare, R Tang, AN Patwa, MW Grinstaff, DJ Kelly, E Alsberg, JD Boerckel. Recapitulating bone development through engineered mesenchymal condensations and mechanical cues for tissue regeneration. Science translational medicine 11 (495), eaav7756, 2019.
63. OR Mahon, DJ Kelly, GM McCarthy, A Dunne. Osteoarthritis-associated basic calcium phosphate crystals alter immune cell metabolism and promote M1 macrophage polarization. Osteoarthritis and cartilage (in press).
64. EJ Sheehy, DJ Kelly, FJ O’Brien. Biomaterial-based endochondral bone regeneration: A shift from traditional tissue engineering paradigms to developmentally inspired strategies. Materials Today Bio, 100009, 2019.
65. DC Browe, OR Mahon, PJ Díaz‐Payno, N Cassidy, I Dudurych, A Dunne, DJ Kelly. Glyoxal cross‐linking of solubilised extracellular matrix to produce highly porous, elastic and chondro‐permissive scaffolds for orthopaedic tissue engineering. Journal of Biomedical Materials Research Part A, 107(10):2222-2234, 2019.
66. Gonzalez-Fernandez T., Rathan S., Hobbs C., Pitacco P., Freeman F.E., Cunniffe G.M., Dunne N.J., McCarthy H., Nicolosi V., O’Brien F.J., Kelly D.J Pore-Forming Bioinks to Enable Spatio-Temporally Defined Gene Delivery in Bioprinted Tissues. Journal of Controlled Release 301, 13-27, 2019.
67. Sridharan, R., Cavanagh, B., Cameron, A., Kelly, D.J. O’Brien, F.J. Material stiffness influences the polarization state, function and migration of macrophages. Acta Biomaterilia 15;89:47-59, 2019.
68. Olvera, D., Schipani, R., Sathy, B., Kelly, D.J. Electrospinning of highly porous yet mechanically functional microfibrillar scaffolds at the human scale for ligament and tendon tissue engineering. Biomedical Materials 14 (3), 035016, 2019.
69. Sathy, B.N., Daly, A., Olvera, D., Fernandez, T.G., Cunniffe, G., Pentlavalli, S., Chambers, P., Dunne, N. McCarthy, H.O., Jeon, O., Alsberg, E., Donahue, T.H., Kelly, D.J. Hypoxia Mimicking Hydrogels to Regulate the Fate of Transplanted Stem Cells. Acta Biomaterilia 88, 314-324, 2019.
70. Daly, A., Kelly, D.J. Biofabrication of spatially organised tissues by directing the growth of cellular spheroids within 3D printed polymeric microchambers. Biomaterials 197, 194-206, 2019.
71. Rathan, S., Dejob, L., Schipani, R., Haffner, B., Möbius, M.E., Kelly, D.J Fiber Reinforced Cartilage ECM Functionalized Bioinks for Functional Cartilage Tissue Engineering. Advanced Healthcare Materials 8 (7), 1801501, 2019.
72. Pauly, H., Kelly, D.J., Popat, K., Palmer, R., Haut Donahue, T.L Mechanical properties of a hierarchical electrospun scaffold for ovine anterior cruciate ligament replacement. Journal of Orthopaedic Research 37 (2), 421-430, 2019.
73. Sridharan, R., Ryan, E.J., Kearney, C.J., Kelly, D.J., O’Brien, F.J. Macrophage Polarization in Response to Collagen Scaffold Stiffness Is Dependent on Cross-Linking Agent Used To Modulate the Stiffness. ACS Biomater. Sci. Eng. 5 (2), 544-552, 2018.
74. Cunniffe, G.M., Díaz-Payno, P.J. Sheehy, E.J. Critchley, S.E., Almeida, H.V., Pitacco, P., Simon F. Carroll, S.F., Mahon, O.R., Dunne, A., Levingstone, T.J., Moran, C.J., Brady, R.T., O’Brien, F.J., Brama, P., Kelly, D.J. Tissue-specific extracellular matrix scaffolds for the regeneration of spatially complex musculoskeletal tissues. Biomaterials 188, 63-73, 2019.
75. Critchley, S., Cunniffe, G.M., O’Reilly, A., Diaz-Payno, P.J., Schipani, R., McAlinden, A., Withers, D., Shin, J.Y., Alsberg, E., Kelly, D.J Regeneration of osteochondral defects using developmentally inspired cartilaginous templates. Tissue Engineering Part A 25 (3-4), 159-171, 2019.

 

2018:

76. Daly, A., Pitacco, P., Nulty, J., Cunniffe, G.M., Kelly, D.J. 3D printed microchannel networks to direct vascularisation during endochondral bone repair. Biomaterials, 162, 34-46, 2018.
77. Gonzalez-Fernandez, T., Kelly, D.J., O’Brien, F.J. Controlled Non‐Viral Gene Delivery in Cartilage and Bone Repair: Current Strategies and Future Directions. Advanced Therapeutics 1 (7), 1800038, 2018.
78. Ryan, A.J., Kearney, C.J., Shen, N., Khan, U., Kelly, A.G., Probst, C., Brauchle, E., Biccai, S., Carciarena, C.D., Kerrigan, S.W. Kelly, D.J., Shenke-Layland, K., Coleman, J.C., O'Brien, F.J. Electroconductive Biohybrid Collagen/Pristine Graphene Composite Biomaterials with Enhanced Biological Activity. Advanced Materials 30(15), e1706442, 2018.
79. McMillan, A., Nguyen, M.K., Gonzalez-Fernandez, T., G, P., Yu, X., Murphy, W.L., Kelly, D.J., Aslberg, E. Dual non-viral gene delivery from microparticles within 3D high-density stem cell constructs for enhanced bone tissue engineering. Biomaterials 161, 240-255, 2018.
80. Daly, A., Kelly, D.J. Engineering Large Cartilage Tissues Using Dynamic Bioreactor Culture at Defined Oxygen Conditions. Journal of Tissue Engineering 2018 Jan-Dec; 9: 2041731417753718.
81. BN Teixeira, P Aprile, RH Mendonça, DJ Kelly, RMSM Thiré. Evaluation of bone marrow stem cell response to PLA scaffolds manufactured by 3D printing and coated with polydopamine and type I collagen. Journal of Biomedical Materials Research Part B: Applied Biomaterials (in press).
82. Mulvihill, J.E., Raykin, J., Snider, E. J., Schildmeyer, L.A., Zaman, I., Platt, M.O., Kelly, D.J., Ethier, R.C. Development of a platform for studying 3D astrocyte mechanobiology: compression of astrocytes in collagen gels. Annals of Biomedical Engineering 46(2):365-374, 2018.
83. Mahon, O.R., O’Hanlon, S., McCarthy, G., Kelly, D.J. Dunne, A. Orthopaedic implant materials drive M1 macrophage polarization in a Spleen Tyrosine Kinase- and Mitogen-Activated Protein Kinase-dependent manner. Acta Biomaterilia 65:426-435, 2018.
84. Romanazzo, S., Moran, C., Kelly, D.J. Meniscus ECM functionalized hydrogels containing infrapatellar fat pad derived stem cells for bioprinting of regionally defined meniscal tissue. Journal of Tissue Engineering and Regenerative Medicine 12(3):e1826-e1835, 2018.
85. Critchley, S., Rajalakshmanan, E., Kelly, D.J. Low oxygen conditions promote synergistic increases in chondrogenesis during co-culture of human osteoarthritic stem cells and chondrocytes. Journal of Tissue Engineering and Regenerative Medicine 12(4):1074-1084, 2018.

 

2017:

86. Freeman, F., Kelly D.J. Tuning Alginate Bioink Stiffness and Composition for Controlled Growth Factor Delivery and to Spatially Direct MSC Fate within Bioprinted Tissues. Scientific Reports 7: 17042 (2017).
87. Carroll, S., Buckley, C.T., Kelly, D.J. Cyclic tensile strain can play a role in directing both intramembranous and endochondral ossification of mesenchymal stem cells. Frontiers in Bioengineering and Biotechnology 5:73. doi: 10.3389/fbioe.2017.00073
88. Vedicherla, S., Romanazzo, S., Kelly, D.J., Moran, C., Buckley, C.T. Chondrocyte-based Intraoperative Processing Strategies for the Biological Augmentation of a Polyurethane Meniscus Replacement. Connective Tissue Research 28:1-12, 2017.
89. Critchley, S., Kelly, D.J. Bioinks for bioprinting functional meniscus and articular cartilage. Journal of 3D Printing in Medicine, 1 (4), 2017.
90. De Oliviera, F., Olvera, D., Sawkins, M., Cryan, S., Kimmins, S., Da Silva, T., Kelly, D.J., Duffy, G., Kearney, C., Heise, A. Direct UV-triggered thiol-ene cross-linking of electrospun polyester fibers from unsaturated poly(macrolactone)s and their drug loading by solvent swelling. Biomacromolecules 18 (12), 4292–4298, 2017.
91. Olvera, D., Sathy, B.N., Carroll, S.F., Kelly, D.J. Modulating microfibrillar alignment and growth factor stimulation to regulate mesenchymal stem cell differentiation. Acta Biomaterilia 64:148-160, 2017.
92. Lebre, F., Sridharan, R., Sawkins, M.J., Kelly, D.J., O’Brien, F.J., Lavelle, E.C. The shape and size of hydroxyapatite particles dictate inflammatory responses following implantation. Scientific Reports 7, Article number: 2922, 2017.
93. do Amaral, R., Almeida, H.V., Kelly, D.J., O'Brien, F.J., Kearney, C.J. Infrapatellar fat pad stem cells: from developmental biology to cell therapy. Stem Cells International https://doi.org/10.1155/2017/6843727
94. Harris E., Liu Y., Cuniffe G., Morrissey D., Carroll S., Mulhall K., Kelly D.J. Biofabrication of soft tissue templates for engineering the bone-ligament interface. Biotechnol Bioeng 114(10):2400-2411, 2017.
95. Daly, A.C., Freeman, F.F., Gonzalez-Fernandez, T., Critchley, S.E., Nulty, J., Kelly, D.J. 3D Bioprinting for Cartilage and Osteochondral Tissue Engineering. Advanced Healthcare Materials 6(22). doi: 10.1002/adhm.201700298.
96. Pentlavalli, S., Chambers, P., Sathy, B.N., O'Doherty, M., Chalanqui, M., Kelly, D.J., Haut-Donahue, T. McCarthy, H.O., Dunne, N. Simple Radical Polymerisation of Poly(Alginate-Graft-N-Isopropylacrylamide) Injectable Thermoresponsive Hydrogel with the Potential for Localised and Sustained Delivery of Stem Cells and Bioactive Molecules. Macromolecular Bioscience 17(11), 2017.
97. Almeida, H., Dikina, A., Mulhall, K., O'Brien, F., Alsberg, E., Kelly, D.J.. Porous Scaffolds Derived from Devitalized Tissue Engineered Cartilaginous Matrix Support Chondrogenesis of Adult Stem Cells. ACS Biomaterials Science & Engineering 3 (6), 1075–1082, 2017.
98. Gonzalez-Fernandez, T., Sathy, B.N., Hobbs, C., Cunniffe, G.M., McCarthy, H.O., Dunne, N.J., Nicolosi, V., O’Brien, F.J., Kelly, D.J. Mesenchymal Stem Cell Fate Following Non-viral Gene Transfection Strongly Depends on the Choice of Delivery Vector. Acta Biomaterialia 55:226-238, 2017.
99. Cunniffe, G.M., Gonzalez-Fernandez, T., Daly, A.C., Sathy, B., Jeon, O., Alsberg, E., Kelly, D.J. 3D Bioprinting of PCL Reinforced Gene Activated Bioinks for Bone Tissue Engineering. Tissue Engineering, Part A 23, 17-18, 2017.
100. Dikina, A., Almeida, H.V., Cao, M., Kelly, Alsberg, E. Scaffolds Derived from ECM Produced by Chondrogenically Induced Human MSC Condensates Support Human MSC Chondrogenesis. ACS Biomaterials Science & Engineering 3 (7), 1426–1436, 2017.
101. Pauly, H.M., Sathy, B., Olvera, O., McCarthy, H.O., Kelly, D.J., Popat, K.C., Dunne, N.J., Haut Donahue, T.L. Hierarchically structured electrospun scaffolds with chemically conjugated growth factor for ligament tissue engineering. Tissue Engineering Part A 23(15-16):823-836, 2017.
102. Rodenas-Rochina, J., Kelly, D.J., Gomez Ribelles, J., Lebourg, M. Influence of oxygen levels on chondrogenesis of porcine mesenchymal stem cells cultured in polycaprolactone scaffolds. Journal of Biomedical Materials Research: Part A 105(6):1684-1691, 2017.
103. Sathy, B.N., Olvera, D., Fernandez, T.G., Cunniffe, G., Pentlavalli, S., Chambers, P., Dunne, N. McCarthy, H.O., Jeon, O., Alsberg, E., Donahue, T.H., Kelly, D.J. RALA complexed α-TCP nanoparticle delivery to mesenchymal stem cells induces bone formation in tissue engineered constructs in vitro and in vivo. Journal of Materials Chemistry B 5, 1753-1764, 2017.
104. Cunniffe, G.M., Díaz-Payno, P.J. Ramey, J.S., Mahon, O. Dunne, A. Thompson, E., O’Brien, F.J., Kelly, D.J. Growth plate extracellular matrix-derived scaffolds for large bone defect healing. European Cells and Materials 33:130-142, 2017.
105. Almeida, A.V, Sathy, B.N., Dudurych, I., Buckley, C.T., O’Brien, F.J.,  Kelly, D.J. Anisotropic Shape-Memory Alginate Scaffolds Functionalized with either Type I or Type II Collagen for Cartilage Tissue Engineering. Tissue Engineering Part A 23(1-2):55-68, 2017.
106. O’Reilly, A., Kelly, D.J. A Computational Model of Osteochondral Defect Repair Following Implantation of Stem Cell Laden Multiphase Scaffolds. Tissue Engineering Part A 23(1-2):30-42, 2017.
107. Anurati, S., Rolfe, R., Carroll, S., Kelly, D.J., Murphy, P. Chondrogenesis of embryonic limb bud cells in micromass culture progresses rapidly to hypertrophy and is modulated by hydrostatic pressure. Cell and Tissue Research, 368: 47–59, 2017.
108. Almeida, A.V, Mulhall, K.J., O’Brien, F.J., Kelly, D.J Stem cells display a donor dependent response to escalating levels of growth factor release from extracellular matrix-derived scaffolds. Journal of Tissue Engineering and Regenerative Medicine 1(11):2979-2987, 2017.

 

2016:

109. Daly, A.C., Critchley, S., Rencsck, E., Kelly, D.J. A comparison of different bioinks for 3D bioprinting of fibrocartilage and hyaline cartilage. Biofabrication, 8(4): 045002, 2016.
110. Verrier, S., Alini M., Alsberg, E., Buchman, S.R., Kelly, D., Laschke, M.W., Menger, M.D., Murphy, W.L., Stegemann, J.P., Schütz, M., Miclau, T., Stoddart, M.J., Evans, C. Tissue engineering and regenerative approaches to improving the healing of large bone defects. Eur Cells & Materials, 32:87-110, 2016.
111. Daly, A.C., Cunniffe, G.M., Sathy, B.N., Jeon, O., Alsberg, E., Kelly, D.J. 3D Bioprinting of Developmentally Inspired Templates for Whole Bone Organ Engineering. Advanced HealthCare Materials 5(18):2353-62, 2016.
112. O'Reilly, A., Kelly, D.J. Unravelling the role of mechanical stimuli in regulating cell fate during osteochondral defect repair. Annals of Biomedical Engineering 44(12):3446-3459, 2016.
113. Gonzalez-Fernandez, T., Tierney, E., Cunniffe, G.M., O’Brien, F.J., Kelly, D.J. Gene Delivery of TGF-β3 and BMP2 in a MSC Laden Alginate Hydrogel for Articular Cartilage and Endochondral Bone Tissue Engineering. Tissue Engineering Part A 22(9-10):776-87, 2016.
114. Steward, A.J., Kelly, D.J., Wagner, D.R. Purinergic Signaling Regulates the TGF-β3-Induced Chondrogenic Response of Mesenchymal Stem Cells to Hydrostatic Pressure. Tissue Engineering Part A (11-12):831-9, 2016.
115. Almeida, A.V, Rajalakshmanan, E., Cunniffe, G.M., Buckley, C.T., O’Brien, F.J.,  Kelly, D.J. Fibrin Hydrogels Functionalized with Particulated Cartilage Extracellular Matrix and Incorporating Freshly Isolated Stromal Cells as an Injectable for Cartilage Regeneration. Acta Biomaterilia 36:55-62, 2016.
116. Lu, L., Chu, J.,  Rajalakshmanan, E.,  Mulhall, K.,  Kelly, D. J. Engineering tissues that mimic the zonal nature of articular cartilage using decellularized cartilage explants seeded with adult stem cells. ACS Biomaterials Science & Engineering1021/acsbiomaterials.6b00020, 2016.
117. Rodenas-Rochina, J., Kelly, D.J., Gomez Ribelles, J., Lebourg, M. Compositional changes to synthetic biodegradable scaffolds modulate the influence of hydrostatic pressure on chondrogenesis of mesenchymal stem cells. Biomedical Physics & Engineering Express 2 035005, 2016.
118. Pauly, H.M., Kelly, D.J., Popat, K.C., Trujillo, N.A., Dunne, N.J., McCarthy, H.O., Haut Donahue, T.L. Mechanical properties and cellular response of novel electrospun nanofibers for ligament tissue engineering: Effects of orientation and geometry. Journal of the Mechanical Behavior of Biomedical Materials, 61, 258 – 270, 2016.
119. , L., O’Reilly, A., Thorpe, S., Buckley, C.T., Kelly, D.J. Engineering zonal cartilaginous tissue by modulating oxygen levels and mechanical cues through the depth of infrapatellar fat pad stem cell laden hydrogels. Journal of Tissue Engineering and Regenerative Medicine 11(9):2613-2628, 2017.
120. Matsiko, A., Thompson, E., Kelly, D.J., Gleeson, J., O’Brien, F.J. An endochondral ossification-based approach to bone repair: Chondrogenically-primed MSC-laden scaffolds support greater repair of critical-sized cranial defects than osteogenically stimulated constructs in vivo. Tissue Engineering (Part A) 22(5-6):556-67, 2016.
121. O’Reilly, A, Hankenson, K., Kelly, D.J. A computational model to explore the role of angiogenic impairment on endochondral ossification during fracture healing. Biomechanics and Modelling in Mechanobiology 15(5):1279-94, 2016.
122. O’Reilly, A., Kelly, D.J. The role of oxygen as a regulator of stem cell fate during the spontaneous repair of osteochondral defects. Journal of Orthopaedic Research 34(6):1026-36, 2016.

 

2015:

123. Mesallati, T., Sheehy, E.J., Vinardell, T., Buckley, C.T., Kelly, D.J. Tissue engineering scaled-up, anatomically shaped osteochondral constructs for joint resurfacing. European Cells and Materials 30:163-85,
124. Luo, L., Eswaramoorthy, R., Kelly, D.J. Decellularization of porcine articular cartilage explants and their subsequent repopulation with human chondroprogenitor cells. Journal of the Mechanical Behavior of Biomedical Materials 55, 21-31, 2015.
125. , L., Thorpe, S., Buckley, C.T., Kelly, D.J. The effects of dynamic compression on the development of cartilage grafts engineered using bone marrow and infrapatellar fat pad derived stem cells. Biomedical Materials, 10 (5), 055011, 2015.
126. Cunniffe, G.M., Vinardell, T., Thompson, E.M., Daly, A., Matsiko, A., O’Brien, F.J., Kelly, D.J. Chondrogenically Primed Mesenchymal Stem Cell-Seeded Alginate Hydrogels Promote Early Bone Formation in Critically-Sized Defects. European Polymers Journal 72, 464-472, 2015.
127. Cunniffe, G.M., Vinardell, T., Murphy, M.J., Thompson, E.M., Matsiko, A., O’Brien, F.J., Kelly, D.J. Porous decellularized tissue engineered hypertrophic cartilage as a scaffold for large bone defect healing. Acta Biomaterilia 23: 82-90, 2015.
128. Mesallati, T., Buckley, C.T., Kelly, D.J. Engineering cartilaginous grafts using chondrocyte-laden hydrogels supported by a superficial layer of stem cells. Journal of Tissue Engineering and Regenerative Medicine 11(5):1343-1353, 2017.
129. Sridharan, R, Cameron, A.R., Kelly, D.J., Kearney, C.J., O’Brien, F.J., Biomaterial based modulation of macrophage polarization: a review and suggested design principles. Materials Today, Vol 18 (6), 313-325, 2015.
130. Sheehy, E.S, Mesallati, T., Kelly, L., Vinardell, T., Buckley, C.T., Kelly, D.J Tissue engineering whole bones through endochondral ossification: Regenerating the distal phalanx. Bioresearch Open Access. 4(1): 229-241, 2015.
131. Gannon, A, Nagel, T., Kelly, D.J. The Changing Role of the Superficial Region in Determining the Dynamic Compressive Properties of Articular Cartilage during Postnatal Development. Osteoarthritis and Cartilage, 23 (6): 975-984, 2015.
132. Almeida, A.V, Cunniffe, G.M., Vinardell, T., Buckley, C.T., O’Brien, F.J.,  Kelly, D.J. Coupling freshly isolated CD44+ infrapatellar fat pad derived stromal cells with a tgf-β3 eluting cartilage ecm-derived scaffold as a single stage strategy for promoting chondrogenesis. Advanced Healthcare Materials 4(7):1043-53, 2015.
133. Gannon, A, Nagel, T., Avery, N., Kelly, D.J. Postnatal changes to the mechanical properties of articular cartilage are driven by the evolution of its collagen network. European Cells and Materials 29: 102-123, 2015.
134. Sheehy, E.S, Mesallati, T., Vinardell, T., Kelly, D.J. Engineering cartilage or endochondral bone: A comparison of different naturally derived hydrogels. Acta Biomaterilia, 13:245-53,

 

2014:

135. Almeida, H.V., Liu, Y., Cunniffe, G., Buckley, C.T., Matsiko, A., O’Brien, F.J., Kelly, D.J. Controlled release of TGF-β3 from cartilage extra cellular matrix derived scaffolds to promote chondrogenesis of human joint tissue derived stem cells. Acta Biomaterilia, 10(10), 4400-9, 2014.
136. Burke, D., Kelly, D.J. A Mechanobiological Model of Endothelial Cell Migration and Proliferation. Computer Methods in Biomechanics and Biomedical Engineering, 19 (1), pp. 74-83, 2016.
137. Steward, A.J., Kelly, D.J., Wagner, D.R. The role of calcium signalling in the chondrogenic response of mesenchymal stem cells to hydrostatic pressure. European Cells and Material, 28, 358-371, 2014.
138. Steward, A.J., Kelly, D.J. Mechanical regulation of mesenchymal stem cell differentiation. Journal of Anatomy, 227 (6), 717-731, 2015.
139. Liu, Y., Buckley, C.T., Almeida, H.V., Mulhall, K.J., Kelly, D.J. Infrapatellar Fat Pad Derived Stem Cells Maintain Their Chondrogenic Capacity in Disease and can be used to Engineer Cartilaginous Grafts of Clinically Relevant Dimensions. Tissue Engineering, Part A, 20(21-22), 3050-62, 2014.
140. Thompson, E.M., Matsiko, A., Farrell, E., Kelly, D.J., O'Brien, F.J. Recapitulating endochondral ossification: A promising route to in vivo bone regeneration. Journal of Tissue Engineering and Regenerative Medicine 9(8):889-902, 2015.
141. Burke, D., Khayyeri, H., Kelly, D.J. Substrate Stiffness and Oxygen Availability as Regulators of Mesenchymal Stem Cell Differentiation within a Mechanically Loaded Bone Chamber. Biomechanics and Modeling in Mechanobiology, 14(1):93-105, 2014.
142. Sheehy, E.S, Vinardell, T., Toner, M., Buckley, C.T., Kelly, D.J. Altering the architecture of tissue engineered hypertrophic cartilaginous grafts facilitates vascularisation and accelerates mineralisation. PLoS One, 9(3), e90716, 2014.
143. Mesallati, T., Buckley, C.T., Kelly, D.J. Engineering articular cartilage-like grafts by self-assembly of infrapatellar fat pad-derived stem cells. Biotechnology and Bioengineering 111(8), 1686–1698, 2014.
144. , S., Buckley, C.T., Kelly, D.J. Cyclic Hydrostatic Pressure Promotes A Stable Cartilage Phenotype And Enhances The Functional Development Of Cartilaginous Grafts Engineered Using Multipotent Stromal Cells Isolated From Bone Marrow And Infrapatellar Fat Pad. Journal of Biomechanics 47, (9), 2115-21, 2014.
145. Rolfe, R.A., Nowlan, N.C., Kenny, E.M., Cormican, P., Morris, D.W., Prendergast, P.J., Kelly, D.J. and Murphy, P. Identification of Mechanosensitive Genes during Skeletal Development: Alteration of genes associated with Cytoskeletal Rearrangement and Cell Signalling Pathways. BMC Genomics, 15:48, 2014.
146. Ahearne, M., Liu, Y., Kelly, D.J. Combining freshly isolated chondroprogenitor cells from the infrapatellar fat pad with a growth factor delivery hydrogel as a putative single stage therapy for articular cartilage repair. Tissue Engineering Part A, 20:930-9, 2014.
147. Mesallati, T., Buckley, C.T., Kelly, D.J. A comparison of self-assembly and hydrogel encapsulation as a means to engineer functional cartilaginous grafts using culture expanded chondrocytes. Tissue Engineering, Part C, 20(1):52-63, 2014.
148. Steward, A.J., Wagner, D.R., Kelly, D.J. Exploring the roles of integrin binding and cytoskeletal reorganization during mesenchymal stem cell mechanotransduction in soft and stiff hydrogels subjected to dynamic compression. Journal of the Mechanical Behavior of Biomedical Materials 38:174-82, 2014.

 

2013:

149. Thorpe, S.D., Nagel, T., Carroll, S.F., Kelly, D.J. Modulating gradients in regulatory signals within mesenchymal stem cell seeded hydrogels: A novel strategy to engineer zonal articular cartilage. PLoS One, 8(4): e60764, 2013.
150. Burke, D., Dishowitz, M., Sweetwyne, M., Miedel, E., Hankenson, K.D., Kelly, D.J. The role of oxygen as a regulator of stem cell fate during fracture repair in tsp2-null mice. Journal of Orthopaedic Research, 31(10):1585-96, 2013.
151. Nagel, T., Kelly, D.J. Altering the swelling pressures within in vitro engineered cartilage is predicted to modulate the configuration of the collagen network and hence improve tissue mechanical properties. Journal of the Mechanical Behavior of Biomedical Materials, 22:22-9, 2013.
152. Liu, Y., Buckley, C.T., Mulhall, K.J., Kelly, D.J. Combining BMP-6, TGF-β3 and hydrostatic pressure stimulation enhances the functional development of cartilage tissues engineered using human infrapatellar fat pad derived stem cells. Biomaterials Science, 1, 745-752, 2013.
153. Steward, A.J., Wagner, D.R., Kelly, D.J. The pericellular environment regulates cytoskeletal development and the differentiation of mesenchymal stem cells and determines their response to hydrostatic pressure. European Cells and Materials, 25, 167-178, 2012.
154. Ahearne, M., Kelly, D.J. A comparison of fibrin, agarose and gellan gum hydrogels as carriers of stem cells and growth factor delivery microspheres for cartilage regeneration. Biomedical Materials, 8(3), 035004, 2013.
155. Cilla, M., Pena, E., Martınez, M.A., Kelly, D.J. Comparison of the vulnerability risk for positive versus negative atheroma plaque morphology. Journal of Biomechanics, 46(7):1248-54, 2013.
156. Mesallati, T., Buckley, C.T., Nagel, T., Kelly, D.J. Scaffold architecture determines chondrocyte response to externally applied dynamic compression. Biomechanics and Modeling in Mechanobiology 12(5):889-99, 2013.
157. Sheehy, E., Vinardell, T., Buckley, C.T., Kelly, D.J. Engineering osteochondral constructs through spatial regulation of endochondral ossification. Acta Biomaterialia, 9(3):5484-92, 2013.
158. Nagel, T., Kelly, D.J. The composition of engineered cartilage at the time of implantation determines the likelihood of regenerating tissue with a normal collagen architecture. Tissue Engineering Part A, 19 (7-8), 824-833, 2013.

 

2012:

159. Thorpe, S. D., Steward, A., Buckley, C. T., Kelly, D. J. European Society of Biomechanics S.M. Perren Award 2012: The external mechanical environment can override the influence of local substrate in determining stem cell fate. Journal of Biomechanics, 45(15), 2483–2492, 2012.
160. Haugh, M.G., Thorpe, S.D., Vinardell, T., Buckley, C.T. and Kelly, D.J. The application of plastic compression to modulate fibrin hydrogel mechanical properties. Journal of the Mechanical Behavior of Biomedical Materials, 16:66-72, 2012.
161. Gannon, A., Nagel, T., Kelly, D.J. The role of the superficial region in determining the dynamic properties of articular cartilage. Osteoarthritis and Cartilage, 20 (11), 1417-1425, 2012.
162. O hEireamhoin, S., Buckley, C.T., Jones, E; McGonagle, D., Mulhall, K. J., Kelly, D J. Recapitulating aspects of the oxygen and substrate environment of the damaged joint milieu for stem cell based cartilage tissue engineering. Tissue Engineering Part C, 19(2):117-2, 2013.
163. Burke, D., Kelly, D.J. Substrate Stiffness and Oxygen as Regulators of Stem Cell Differentiation during Tissue Differentiation: A Mechanobiological Model. PLoS One, 7 (7), e40737, 2012.
164. Vinardell, T., Rolfe, R.A., Buckley, C.T., Meyer, E.G., Ahearne, M., Murphy, P., Kelly, D.J. Hydrostatic pressure acts to stabilise a chondrogenic phenotype in porcine joint tissue derived stem cells. e Cells and Materials, 23, 121-34, 2012.
165. Boccaccio, A., Kelly, D.J., Pappalettere, C. A model of tissue differentiation and bone remodelling in fractured vertebrae treated with minimally invasive percutaneous fixation. Medical & Biological Engineering & Computing, 50 (9), 947-959, 2012.
166. Liu, Y., Buckley, C.T., Downey, R., Mulhall, K.J., Kelly, D.J. The role of environmental factors in regulating the development of cartilaginous grafts engineered using osteoarthritic human infrapatellar fat pad derived stem cells. Tissue Engineering Part A, 18(15-16):1531-41, 2012.
167. Vinardell, T., Sheehy, E., Buckley, C.T., Kelly, D.J. A comparison of the functionality and in vivo phenotypic stability of cartilaginous tissues engineered from different stem cells sources. Tissue Engineering Part A, 18(11-12), 1161-1170, 2012.
168. Steward, A.J., Thorpe, S.D., Buckley, C.T., Wagner, D.R., Kelly, D.J. Cell-matrix interactions regulate mesenchymal stem cell response to hydrostatic pressure. Acta Biomaterialia, 8, 2153–2159, 2012.
169. Maher, E., Creane, A., Lally, C. Kelly, D.J. Site Specific Inelasticity of Arterial Tissue. Journal of Biomechanics, 45 (8), 1393-1399, 2012.
170. Maher, E., Creane, A., Lally, C. Kelly, D.J. An anisotropic inelastic constitutive model to describe stress softening and permanent deformation in arterial tissue. Journal of the Mechanical Behavior of Biomedical Materials, 12, 9-19, 2012.
171. Buckley, C.T., Meyer, E.G., Kelly, D.J. The Influence of Construct Scale on the Composition and Functional Properties of Cartilaginous Tissues Engineered Using Bone-Marrow Derived Mesenchymal Stem Cells. Tissue Engineering Part A, 18(3-4), 382-96, 2012.
172. Nagel, T., Kelly, D.J. Apparent behaviour of charged and neutral materials with ellipsoidal fibre distributions and cross-validation of finite element implementations. Journal of the Mechanical Behavior of Biomedical Materials, 9, 122-129, 2012.
173. Sheehy, E., Buckley, C.T., Kelly, D.J. Oxygen Tension Regulates the Osteogenic, Chondrogenic and Endochondral Phenotype of Bone Marrow derived Mesenchymal Stem Cells. Biochemical and Biophysical Research Communications, 417, 305-310, 2012.
174. Buckley, C.T., Kelly, D.J. Expansion in the Presence of FGF-2 Enhances the Functional Development of Cartilaginous Tissues Engineered using Infrapatellar Fat Pad Derived MSCs. Journal of the Mechanical Behavior of Biomedical Materials, 11, 102-111, 2012.
175. Nagel, T., Kelly, D.J. Mechanically induced structural changes during dynamic compression of engineered cartilaginous constructs can potentially explain increases in bulk mechanical properties. Journal of the Royal Society Interface, 9 (69), 777-789, 2012.
176. Haugh, M.G., Meyer, E.G., Thorpe, S.D., Vinardell, T., Duffy, G.P. and Kelly, D.J. Temporal and Spatial Changes in Cartilage-Matrix Specific Gene Expression in Mesenchymal Stem Cells in Response to Dynamic Compression. Tissue Engineering Part A , 17 (23-24), 3085-3093, 2011.
177. Creane, A., Maher, E., Sultan, S., Hynes, N., Kelly, D.J., Lally, C. A remodelling metric for angular fibre distributions and its application to diseased carotid bifurcations. Biomechanics and Modeling in Mechanobiology, 11 (6), 869-882, 2012.
178. Nagel, T., Kelly, D.J. Remodelling of collagen fibre transition stretch and angular distribution in soft biological tissues and cell-seeded hydrogels. Biomechanics and Modeling in Mechanobiology, 11, 325-339, 2012.

 

2011:

179. Ahearne, M., Buckley, C.T., Kelly, D.J. A growth factor delivery system for chondrogenic induction of infrapatellar fat-pad derived stem cells in fibrin hydrogels. Biotechnology and Applied Biochemistry, 58(5), 345-352, 2011.
180. Kasiri, S., Kelly DJ. An Argument for the Use of Multiple Segment Stents in Curved Arteries. Journal of Biomechanical Engineering, 133 (8), 084501, 2011.
181. Early, M., Kelly D.J. The consequences of the mechanical environment of peripheral arteries for nitinol stenting. Medical and Biological Engineering and Computing, 49 (11), 1279-88, 2011
182. Hoey, D.A., Kelly, D.J., Jacobs, C.R. A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells. Biochemical and Biophysical Research Communications, 412 (1), 182-187, 2011.
183. Maher, E., Creane, A., Sultan, S., Hynes, N., Lally, C. Kelly, D.J. Inelasticity of Human Carotid Atherosclerotic Plaque. Annals of Biomedical Engineering, 39(9), 2445-2455, 2011.
184. Meyer, E., Buckley, C.T., Steward, A., Kelly, D.J. The effect of cyclic hydrostatic pressure on the functional development of cartilaginous tissues engineered using bone marrow derived mesenchymal stem cells. Journal of the Mechanical Behavior of Biomedical Materials, 4 (7), 1257-1265, 2011.
185. Cummins, F., O' Reilly, P., Flannery, O., Kelly, D., Kenny, P. Defining the impaction frequency and threshold force required for femoral impaction grafting in revision hip arthroplasty. A human cadaveric mechanical study. Acta Orthopaedica, 82(4), 433-437, 2011.
186. Sheehy, E., Buckley, C.T., Kelly, D.J. Chondrocytes and bone marrow derived mesenchymal stem cells undergoing chondrogenesis in agarose hydrogels of solid and channelled architectures respond differentially to dynamic culture conditions. Journal of Tissue Engineering and Regenerative Medicine, 5(9), 747-758, 2011.
187. Creane, A., Maher, E., Sultan, S., Hynes, N., Kelly, D.J., Lally, C. Prediction of fibre architecture and adaptation in diseased carotid bifurcations. Biomechanics and Modeling in Mechanobiology, 10 (6), 831-843, 2011.
188. Vinardell, T., Buckley, C.T., Thorpe, D., Kelly, D.J. Composition-function relations of cartilaginous tissues engineered from chondrocytes and mesenchymal stem cells isolated from bone marrow and infrapatellar fat pad. Journal of Tissue Engineering and Regenerative Medicine, 5(9), 673-683, 2011.
189. Boccaccio, A., Kelly, D.J., Pappalettere, C. A Multi-scale Mechano-Regulation Model of Fracture Repair in Vertebral Bodies. Journal of Orthopaedic Research, 29 (3), 433-443, 2011.
190. Kasiri, S., Kelly, D.J. Taylor, D. Can The Theory of Critical Distances Predict the Failure of Shape Memory Alloys? Computer Methods in Biomechanics and Biomedical Engineering, 14 (6), 491-496, 2011.

 

2010:

191. Buckley, C.T., Vinardell, T., Kelly, D.J. Oxygen Tension Differentially Regulates the Functional Properties of Cartilaginous Tissues Engineered from Infrapatellar Fat Pad Derived MSCs and Articular Chondrocytes. Osteoarthritis and Cartilage, 18 (10), 1345-1354, 2010.
192. Nagel, T., Kelly, D.J. The Influence of Fibre Orientation on the Equilibrium Properties of Neutral and Charged Biphasic Tissues. Journal of Biomechanical Engineering, 132 (11), 114506, 2010.
193. Meyer, E.G., Buckley, C.T., Thorpe, S. D., Kelly, D. J. Low oxygen tension is a more potent promoter of chondrogenic differentiation than dynamic compression. Journal of Biomechanics, 43 (13), 2516-2523, 2010.
194. Thorpe, S. D., Buckley, C. T., Vinardel, T., O’Brien, F. J., Campbell, V. A., Kelly, D. J. The response of bone marrow derived mesenchymal stem cells to dynamic compression following TGF-β3 induced chondrogenic differentiation. Annals of Biomedical Engineering, 38 (9), 2896-2909, 2010.
195. Kelly, D.J. Jacobs, C.R. The Role of Mechanical Signals in Regulating Chondrogenesis and Osteogenesis of Mesenchymal Stem Cells. Birth Defects Research (Part C) 90:75–85 (2010).
196. Zahedmanesh, H., Kelly, D.J., Lally, C. Simulation of a balloon expandable stent in a realistic coronary artery; Determination of the optimum modelling strategy. Journal of Biomechanics, 43 (11) 2126-2132, 2010.
197. Nagel, T., Kelly, D.J. Mechano-regulation of mesenchymal stem cell differentiation and collagen organisation during skeletal tissue repair. Biomechanics and Modeling in Mechanobiology, 9 (3), 359-372, 2010.
198. Partap, S., Plunkett, N.A., Kelly, D.J., O’Brien, F.J. Stimulation of Osteoblasts Using Rest Periods during Bioreactor Culture on Collagen-Glycosaminoglycan Scaffolds. Journal of Material Science: Materials in Medicine, 21(8), 2325-2330, 2010.
199. Boyle, C.J., Lennon, A.B., Early, M., Kelly, D.J., Lally, C., Prendergast, P.J. Computational simulation methodologies for mechanobiological modelling: A cell-centred approach to neointima development in stents. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 368 (1921): 2919-2935, 2010.
200. Buckley, C T; Vinardell, T; Thorpe, S D; Jones, E; McGonagle, D; Kelly, D J. Functional Properties of Cartilaginous Tissues Engineered From Infrapatellar Fat Pad Derived Mesenchymal Stem Cells. Journal of Biomechanics, 43(5): 920-926, 2010.
201. Creane, A., Maher, E., Sultan, S., Hynes, N., Kelly, D.J., Lally, C. Finite element modelling of diseased carotid bifurcations generated from in vivo computerised tomographic angiography. Computers in Biology and Medicine, 40 (4), 419-429, 2010.
202. Early, M., Kelly, D.J. The role of vessel geometry and material properties on the mechanics of stenting in the coronary and peripheral arteries. Proceedings of the Institution of Mechanical Engineers, Part H, Journal of Engineering in Medicine, 224 (3), 465-476,

 

2009:

203. Vinardell, T; Thorpe, S D; Buckley, C T; Kelly, D J. Chondrogenesis and integration of mesenchymal stem cells within an in vitro cartilage defect repair model. Annals of Biomedical Engineering, 37 (12): 2556-2565, 2009.
204. Maher, E., Creane, A., Sultan, S., Hynes, N., Lally, C. Kelly, D.J. Tensile and compressive properties of fresh human carotid atherosclerotic plaques. Journal of Biomechanics, 42 (16): 2760-2767, 2009.
205. Buckley, C.T., Thorpe, D., Kelly, D.J. Engineering of large cartilaginous constructs through the use of microchanneled hydrogels and rotational culture. Tissue Engineering (Part A), 15(11): 3213-3220, 2009.
206. Buckley, C.T., Thorpe, D., O’Brien, F.J., Robinson, A.J., Kelly, D.J. The effect of concentration, cooling rate and cell seeding density on the initial mechanical properties of agarose hydrogels. Mechanical Behaviour of Biomedical Materials, 2, 512-521, 2009.
207. Pericevic, , Lally, C., Toner, D., Kelly, D.J. The influence of plaque composition on underlying arterial wall stress during stent expansion: the case for lesion-specific stents, Medical Engineering and Physics, 31, 428-433, 2009.
208. Jungreuthmayer, C., Jaasma, M.J., Al-Munajjed, A.A., Zanghellini, J., Kelly, D.J., O'Brien, F.J. Deformation simulation of cells seeded on a collagen-GAG scaffold in a flow perfusion bioreactor using a sequential 3D CFD-elastostatics model. Medical Engineering and Physics, 31, 420-427, 2009.
209. Jungreuthmayer, C., Donahue, S.W., Jaasma, M.J., Al-Munajjed, A.A., Zanghellini, J., Kelly, D.J., O'Brien, F.J. A comparative study of shear stresses in collagen-GAG and calcium phosphate scaffolds in bone tissue-engineering bioreactors. Tissue Engineering, 15, 1141-1149, 2009.
210. Early, M., Lally, C., Prendergast, P.J., Kelly, D.J. Stresses in peripheral arteries following stenting: A finite element analysis. Computer Methods in Biomechanics and Biomedical Engineering, 12:1, 25-33, 2009.

 

2008:

211. Thorpe, S. D., Buckley, C. T., Vinardel, T., O’Brien, F. J., Campbell, V. A., Kelly, D. J. Dynamic compression can inhibit chondrogenesis of mesenchymal stem cells. Biochemical and Biophysical Research Communications 337, 458-462, 2008.
212. Boccaccio, A., Prendergast, P.J., Pappalettere, C., Kelly, D.J. Tissue differentiation and bone regeneration in an osteotomized mandible: a computational analysis of the latency period. Medical and Biological Engineering and Computing 46:283-298, 2008.
213. Vard, J., Kelly, D.J., Blayney, A.W., Prendergast, P.J. The influence of ventilation tube design on the magnitude of stress imposed at the implant/tympanic membrane interface. Medical Engineering & Physics, 30, 154-163, 2008.

 

2007:

214. Kelly, D. J., Crawford, A., Dickinson, S.C., Sims, T., Mundy, J., Hollander A. P., Prendergast, P.J, & Hatton, P. V. Biochemical Markers of the Mechanical Quality of Engineered Hyaline Cartilage. Journal of Material Science 18, 273-81, 2007.
215. Boccaccio, A., Pappalettere, C., Kelly, D.J. The influence of expansion rates on mandibular distraction osteogenesis: a computational analysis. Annals of Biomedical Engineering, 35, 1940-60, 2007.
216. Guerin, S., O’Reilly, P., O’Byrne, J., Kelly, D.J. Hydrogen peroxide as a clinical irrigation solution: A comparative study of the effect of hydrogen peroxide versus normal saline on the strength of the bone-cement interface. Biomedical Materials and Engineering 17, 379-86, 2007.
217. Byrne, D. P., Lacroix, D., Kelly, D. J., Plannel, J. A., Prendergast, P. J. Simulation of tissue differentiation in a scaffold as a function of porosity, Young's modulus and dissolution rate: Application of mechanobiological models in tissue engineering. Biomaterials, 28, 5544-54, 2007.
218. Marenzana, M., Kelly, D.J., Prendergast, P.J., Brown, R.A. A collagen-based interface construct for the assessment of cell-dependent mechanical integration of tissue surfaces. Cell and Tissue Research. 327: 293-300, 2007.

 

2006:

219. Kelly, D.J. & Prendergast, P.J. Prediction of the optimal mechanical properties for a scaffold used in osteochondral defect repair. Tissue Engineering 12, 2509-2529, 2006.

 

2005:

220. Kelly, D.J. & Prendergast, P.J. Mechano-regulation of stem cell differentiation and tissue regeneration in osteochondral defects. Journal of Biomechanics, 38, 1413-1422, 2005.
221. Moretti, M., Wendt, D., Dickinson, S.C., Sims, T.J. Hollander, A.P., Kelly, D.J. Prendergast, P.J., Heberer, M., Martin, I. Effects of in vitro pre-culture on the in vivo development of human engineered cartilage in an ectopic model. Tissue Engineering, 11, 1421-1428, 2005.

 

2004:

222. Kelly, D.J. & Prendergast, P.J. Effect of a degraded core on the mechanical behavior of tissue-engineered cartilage constructs: a poro-elastic finite element analysis. Medical & Biological Engineering & Computing, 45, 9-13, 2004.

 

2003:

223. Kelly, D.J., Prendergast, P.J & Blayney, A.W. The effect of prosthesis design on vibration of the reconstructed ossicular chain: a comparative finite element analysis of four prostheses. Otology & Neurotology, 24, 11 – 19, 2003.
224. Kelly, D.J., Blayney, A.W. & Prendergast, P.J. Biomechanics of ossiculoplasty, CME Bulletin Otorhinolaryngology Head and Neck Surgery. 7, 64 – 66, 2003.

 

1999:

225. Prendergast, P.J., Kelly, D.J., Rafferty, M. & Blayney, A.W.. The effect of ventilation tubes on stresses and vibration motion in the tympanic membrane: a finite element analysis, Clinical Otolaryngology and Allied Sciences. 24, 542 – 548, 1999.