Professor Patrick Prendergast
Research Professor, Mechanical, Manuf & Biomedical Eng
Email PATRICK.PRENDERGAST@tcd.ie Phone https://www.tcd.ie/biomedicalengineering/Biography
Patrick Prendergast, BA, BAI, PhD, ScD, C.Eng, FIEI, FIAE, FREng, MRIA, SFTCD is an Honorary Principal Investigator in the Trinity Centre for Biomedical Engineering (TCBE). Together with colleagues from Engineering, Medicine and Dentistry, he led the application to establish the TCBE under the Programme for Research in Third-level Institutions (PRTLI). He was the inaugural Director from 2003 to 2008. Dr Prendergast was Professor of Bio-Engineering from 2007 until his appointment as President/Provost required him to relinquish his professorship in 2011. In 2011 he was appointed the 44th President & Provost of Trinity College Dublin and held office for a 10-year term. Prior positions in university administration were Chief Academic Officer & Vice-Provost (2008-2011), and Dean of Graduate Studies (2004-2007). Further details on former Provosts are given at www.tcd.ie/provost/biography/former-provosts/patrick-prendergast-/. On returning to the faculty in 2021, he was appointed as Research Professor in the University. Prior to working in TCD he held post-doctoral positions in Rizzoli Orthopaedic Institute, Bologna and the University of Nijmegen, The Netherlands, where he worked with Prof.dr.ir. Rik Huiskes. On a sabbatical year 2001-2002 he was Visiting Professor, Institute of Fundamental Technological Research, Poland and Senior Research Fellow, Koiter Institute, Technical University of Delft and the Department of Orthopaedics of Erasmus University Rotterdam, The Netherlands. He also did a sabbatical year at the Institute of Bioengineering of UPC, Barcelona, Spain in 2007-2008 working with Professor Josep Planell. His engineering work is in biomechanics, implant analysis and design, and mechanobiology of skeletal tissues. For several decades his publications have appeared in the Elsevier World's Top 2% Scientists Ranking. Graduate Students in Engineering (alphabetical order) Boyle, Colin; PhD; 2011 Britton, John; PhD; 2004 Byrne, Damien; PhD; 2009 Carriero, Allesandra; MS; 2002 Connolly, Paul; MCh; 2000; Co-advisor: Mr J. MacElwaine, FRCSI, Tallaght Hospital Ferris, Peter; MSc; 1998 Flannery, Olivia; MCh; 2007; Co-advisor: Mr J. MacElwaine, FRCSI, Tallaght Hospital Galibarov, Pavel; PhD; 2010; Co-supervisor: Dr Alex Lennon Keeling, Parnell; MCh; 2009; Co-advisor, Mr Paddy Kenny, FRCSI, James Connolly Memorial Hospital Kelly, Daniel; MSc;2001 Kelly, Daniel; PhD; 2004 Kenny, Paddy; MCh; 2003; Co-advisor: Mr J. MacElwaine, FRCSI, Tallaght Hospital Khayyeri, Hanifeh; PhD; 2011 Lacroix, Damien; MSc; 1998 Lacroix, Damien; PhD; 2001 Lally, Catriona; PhD; 2004 Lennon, Alexander; PhD; 2003 Lowrey, Colm; MSc; 2010 MacNicoll, Ruari; MCh; 2008; Co-advisor, Mr Paddy Kenny, FRCSI, James Connolly Memorial Hospital Maher, Suzanne; PhD; 2000 McCormack, Brendan; PhD; 1997; External Supervisor under UCD PhD regulations (Nominating Professor: D.F. Moore) McGarry, James; PhD; 2005; Co-supervisor Prof. Suzi Jarvis, SFI Nanoscience Laboratory McLoughlin, Ruth; MSc; 2008 McMahon, Louise; PhD; 2007; Co-supervisor: Prof. Veronica Campbell, Department of Physiology McNamara, Laoise; PhD; 2004 Moretti, Matteo; MSc; 2001; Co-supervisor: Dr Adrielle Prina-Mello Mulvihill, Brianne; PhD; 2009 Murphy, Bruce; PhD; 2001 Murphy, Linda; PhD; 2002 Nowlan, Niamh; PhD; 2007; Joint supervision with Prof Paula Murphy, Department of Zoology Prina-Mello, Adrielle; PhD; 2003; Co-supervisor: Prof. Y. Volkov, School of Medicine Roddy, Karen; PhD; 2010; Joint supervision with Prof Paula Murphy, Department of Zoology Scannell, Paul; PhD; 2006 Toland, Simon; MSc; 1993; Co-Supervisor Prof David Taylor, Mechanical Engineering Vard, John; MSc; 2004 Waller, Mary; MSc; 2004; Co-supervisor: Prof. Fergal O'Brien, RCSI Walsh, Laura; MSc; 2004 Wulliamoz, Patrick; PhD; 2012 Xue, Feng; PhD; 2014
Publications and Further Research Outputs
- Xue, F. Lennon, A.B. McKayed, K.K. Campbell, V.A. Prendergast, P.J., Effect of membrane stiffness and cytoskeletal element density on mechanical stimuli within cells: an analysis of the consequences of ageing in cells, Computer Methods in Biomechanics and Biomedical Engineering, 18, (5), 2015, p468 - 476Journal Article, 2015, DOI , URL , TARA - Full Text
- Taylor, M. Prendergast, P.J., Four decades of finite element analysis of orthopaedic devices: Where are we now and what are the opportunities?, Journal of Biomechanics, 48, (5), 2015, p767 - 778Journal Article, 2015, DOI , URL , TARA - Full Text
- Huiskes, R, Vandriel, WD, Prendergast, PJ, Soballe, K, A biomechanical regulatory model for periprosthetic fibrous-tissue differentiation, Journal of Materials Science-Materials in Medicine, 8, 1997, p785-788Journal Article, 1997
- Mello, AP, Bari, MA, Prendergast, PJ, A comparison of excimer laser etching and dry etching process for surface fabrication of biomaterials, Journal of Materials Processing Technology, 124, 2002, p284 - 292Journal Article, 2002
- Lacroix, D, Prendergast, PJ, A mechano-regulation model for tissue differentiation during fracture healing: analysis of gap size and loading, Journal of Biomechanics, 35, 2002, p1163 - 1171Journal Article, 2002
- Taylor, D, Prendergast, PJ, A model for fatigue crack propatation and remodelling in compact bone, Proceedings of the Institution of Mechanical Engineers Part H-Journal of Engineerign in Medicine, 211, 1997, p369-375Journal Article, 1997
- McCormack, BAO, Walsh, CD, Wilson, SP, Prendergast, PJ, A statistical analysis of microcrack accumulation in PMMA under fatigue loading: applications to orthopaedic implant fixation, International Journal of Fatigue, 20, 1998, p581-593Journal Article, 1998
- McCormack, BAO, Prendergast, PJ, An analysis of crack propagation paths at implant/bone-cement interfaces, Journal of Biomechanical Engineering-Transactions of the ASME, 118, (4), 1996, p579-585Journal Article, 1996, DOI , URL
- McCormack, BAO, Prendergast, PJ, Gallagher, DG, An experimental study of damage accumulation in cemented hip prostheses, Clinical Biomechanics, 11, (4), 1996, p214-219Journal Article, 1996, DOI , URL
- Prendergast, PJ, Birthistle, P, Waide, DV, Kumar, NVG, An investigation of the performance of biostop G and Hardinge bone plugs, Proceedings of the Institution of Mechanical Engineers Part H-Journal of Engineering in Medicine, 213, 1999, p361-365Journal Article, 1999
- Lacroix, D, Prendergast, PJ, Li, G, Marsh, D, Biomechanical model to simulate tissue differentiation and bone regeneration: application to fracture healing, Medical & Biomechanical Engineering & Computing, 40, 2002, p14-21Journal Article, 2002
- Prendergast, PJ, Biophysical stimuli on cells during tissue differentiation at implant interfaces, Journal of Biomechanics, 30, 1997, p539-548Journal Article, 1997
- Prendergast, PJ, Gorey, TF, Collaborative bioengineering: clinical activities in Ireland, 1999, - 2-2Miscellaneous, 1999
- Maher, SA, Prendergast, PJ, Reid, AJ, Waide, DV, Toni, A, Design and validation of a machine for reproducible precision insertion of femoral hip prostheses for preclinical testing, Journal of Biomechanical Engineering-Transactions of the ASME, 122, 2001, p203-207Journal Article, 2001
- Maher, SA, Prendergast, PJ, Discriminating the loosening behaviour of cemented hip prostheses using measurements of migration and inducible displacement, Journal of Biomechanics, 35, 2002, p257 - 265Journal Article, 2002
- Prendergast, PJ, McCormack, BAO, ESB Keynote Lecture - Dublin 2000 - Outcomes of the 12th Conference of the European Society of Biomechanics, Editorial, 2002, - 399-400Miscellaneous, 2002
- McCormack, BAO, Prendergast, PJ, ODwyer, B, Fatigue of cemented hip replacements under torsional loads, Fatigue & Fracture of Engineering Materials & Structures, 22, 1999, p33-40Journal Article, 1999
- Van Doorn, WJ, Van Biezen, FC, Prendergast, PJ, Fracture of an exeter stem 3 years after impaction allografting - a case report, Acta Orthopaedica Scandinavica, 73, 2002, p111-113Journal Article, 2002
- Prendergast, PJ, Maher, SA, Issues in pre-clinical testing of implants, Journal of Materials Processing Technology, 118, 2002, p337-342Journal Article, 2002
- Murphy, BP, Prendergast, PJ, Measurement of non-linear microcrack accumulation rates in polymethylmethacrylate bone cement under cyclic loading, Journal of Materials Science-Materials in Medicine, 10, 1999, p779-781Journal Article, 1999
- Maher, SA, Prendergast, PJ, Lyons, CG, Measurement of the migration of a cemented hip prosthesis in an in-vitro test, Clinical Biomechanics, 16, 2001, p307-314Journal Article, 2001
- Prendergast, PJ, Mechanics applied to skeletal ontogeny and phylogeny, Meccanica, 37, 2002, p317-334Journal Article, 2002, DOI , TARA - Full Text
- van der Meulen, MCH, Prendergast, PJ, Mechanics in skeletal development, adaptation and disease, Philosophical Transactions of the Royal Society of London Series A - Mathematical Physical and Engineering Sciences, 358, 2000, p565-578Journal Article, 2000
- McCormack, BAO, Prendergast, PJ, Microdamage accumulation in the cement layer of hip replacements under flexural loading, Journal of Biomechanics, 32, 1999, p467-475Journal Article, 1999
- Ferris, P, Prendergast, PJ, Middle-ear dynamics before and after ossicular replacement, Journal of Biomechanics, 33, 2000, p581-590Journal Article, 2000
- Prendergast, PJ, Beverland, DE, Blayney, AW, Dunne, NJ, Gorey, TF, Grace, PA, McCormack, BAO, McGloughlin, T, OConnell, PR, Orr, JF, Modelling medical devices: the application of bioengineering in surgery, Irish Journal of Medical Science, 168, 1999, p3-7Journal Article, 1999
- Murphy, BP, Prendergast, PJ, On the magnitude and variability of the fatigue strength of acrylic bone cement, International Journal of Fatigue, 22, 2000, p855-864Journal Article, 2000
- McNamara, BP, Prendergast, PJ, Taylor, D, Prediction of bone adaptation in the ulnar-osteotomized sheeps forelimb using an anatomical finite-element model, Journal of Biomedical Engineering, 14, (3), 1992, p209-216Journal Article, 1992, URL
- Prendergast, PJ, Taylor, D, Prediction of bone adaptation using damage accumulation, Journal of Biomechanics, 27, (8), 1994, p1067-1076Journal Article, 1994, DOI , URL
- Lennon, AB, Prendergast, PJ, Residual stress due to curing can initiate damage in porous bone cement: experimental and theoretical evidence, Journal of Biomechanics, 35, (3), 2002, p311 - 321Journal Article, 2002, DOI
- Lacroix, D, Prendergast, PJ, Stress analysis of glenoid component designs for shoulder arthroplasty, Proceedings of the Institution of Mechanical Engineers Part H-Journal of Engineering in Medicine, 211, 1998, p467-474Journal Article, 1998
- Prendergast, PJ, Taylor, D, Stress-analysis of the proximomedial femur after total hip-replacement, Journal of Biomedical Engineering, 12, (5), 1990, p379-382Journal Article, 1990, DOI , URL
- Murphy, LA, Prendergast, PJ, Resch, H, Structural analysis of an offset-keel design glenoid component compared to a centre-keel design, Journal of Shoulder and Elbow Surgery, 10, 2002, p568-579Journal Article, 2002
- Prendergast, PJ, The biomechanics of Wolff's Law - recent advances, Irish Journal of Medical Science, 164, 1995, p152-154Journal Article, 1995
- Prendergast, PJ, Kelly, DJ, Rafferty, M, Blayney, AW, The effect of ventilation tubes on stresses and vibration motion in the tympanic membrane: a finite element analysis, Clinical Otolaryngology, 24, 2000, p542-548Journal Article, 2000
- Prendergast, PJ, The functional performance of orthopaedic bone cement, Key Engineering Materials, 198-1, 2001, p291-299Journal Article, 2001
- Murphy, BP, Prendergast, PJ, The relationship between stress, porosity, and nonlinear damage accumulation in acrylic bone cement, Journal of Biomedical Materials Research, 59, 2002, p646-654Journal Article, 2002
- Lacroix, D, Murphy, LA, Prendergast PJ, Three-dimensional finite element analysis of glenoid replacement prostheses: a comparison of keeled and pegged anchorage systems, Journal of Biomechanical Engineering-Transactions of the ASME, 123, 2000, p430-436Journal Article, 2000
- Weinans, H, Prendergast, PJ, Tissue adaptation as a dynamical process far from equilibrium, Bone, 19, (2), 1996, p143-149Journal Article, 1996, DOI , URL
- Prendergast, PJ, Ferris, P, Rice, HJ, Blayney, AW, Vibro-acoustic modelling of the outer and middle ear using the finite-element method, Audiology and Neuro-Otology, 4, 1999, p185-191Journal Article, 1999
- The state-of-the-art in cartilage bioreactors. in, editor(s)PJ Prendergast, PE McHugh , Topics in Bio-Mechanical Engineering, Dublin, Trinity Centre for Bioengineering & National Centre for Biomedical Engineering Science, 2004, pp94 - 146, [McMahon LA, Barron V, Prina-Mello A, Prendergast PJ ]Book Chapter, 2004
- Prina_Mello, A, Farrell, E, Prendergast, PJ, Campbell, V, Coey, JMD, Effects of static magnetic fields on Primary cortical neurons, Physica Scripta, T118, 2005, p205 - 207Journal Article, 2005, DOI , URL
- Prina-Mello A., Farrell E., Prendergast P.J., Campbell V., Coey J.M.D. , Influence of Strong Static Magnetic Fields on Primary Cortical Neurons, Bioelectromagnetics, 27, (1), 2006, p35 - 42Journal Article, 2006, DOI , URL
- Moretti M., Prina_Mello A., Reid A.J., Barron V., Prendergast P.J. 2004. , Endothelial cell alignment on cyclically-stretched silicone surfaces., Journal of Materials Science: Materials in Medicine , 15, (10), 2004, p1159 - 1164Journal Article, 2004, DOI , URL
- Prina-Mello A., Volkov Y., Kelleher D., Prendergast P.J., Comparative locomotory behaviour of T Lymphocytes versus T Lymphoma cells on flat and grooved surfaces., Annals of Biomedical Engineering. , 31, 2003, p1106 - 1113Journal Article, 2003, DOI
- Prina_Mello A., Bari M.A. Prendergast, P.J. , A comparison of excimer laser etching and dry etching process for surface fabrication of biomaterials., Journal of Materials Processing Technology , 124, 2002, p284 - 292Journal Article, 2002, URL
- Britton, JR, Lyons, CG, Prendergast, PJ, Measurement of the relative motion between an implant and bone under cyclic loading, Strain, 40, 2004, p193 - 202Journal Article, 2004
- Lally, C, Reid, AJ, Prendergast, PJ, Elastic behaviour of porcine coronary arteries under uniaxial and equibiaxial tension, Annals of Biomedical Engineering, 32, 2004, p1355 - 1364Journal Article, 2004
- McGarry, JG, Prendergast, PJ, A three-dimensional computational model of an adherent eukaryotic cell, European Cells and Materials, 7, 2004, p27 - 34Journal Article, 2004
- Kelly, DJ, Prendergast, PJ, Effect of a degraded core on the mechanical behaviour of tissue-engineered cartilage constructs: a poro-elastic finite element analysis, Medical and Biological Engineering and Computing, 42, 2004, p9 - 13Journal Article, 2004, TARA - Full Text
- McGarry, JG, Klein-Nulend, J, Mullender, MG, Prendergast, PJ, A comparison of strain and fluid shear stress in stimulating bone cell responses - a computational and experimental study, The FASEB Journal, 19, 2005, p482 - 484Journal Article, 2005, DOI , TARA - Full Text
- DJ Kelly and PJ Prendergast, Mechano-regulation of stem cell differentiation and tissue regeneration in osteochondral defects, Journal of Biomechanics, 38, (7), 2005, p1413 - 1422Journal Article, 2005, DOI , URL , TARA - Full Text
- DJ Kelly and PJ Prendergast, Effect of a degraded core on the mechanical behaviour of tissue-engineered cartilage constructs: a poro-elastic finite element analysis, Medical & Biological Engineering & Computing, 45, (1), 2004, p9 - 13Journal Article, 2004, DOI , URL
- Kelly, D J; Prendergast, P J; Blayney, A W, The effect of prosthesis design on vibration of the reconstructed ossicular chain: a comparative finite element analysis of four prostheses, Otology & Neurotology: Official Publication Of The American Otological Society, American Neurotology Society [And] European Academy Of Otology And Neurotology, 24, (1), 2003, p11 - 19Journal Article, 2003, URL , TARA - Full Text
- Prendergast, P J; Kelly, D J; Rafferty, M; Blayney, A W, The effect of ventilation tubes on stresses and vibration motion in the tympanic membrane: a finite element analysis, Clinical Otolaryngology And Allied Sciences, 24, (6), 1999, p542 - 548Journal Article, 1999, DOI , URL
- Kelly, DJ, Blayney, AW, Prendergast, PJ, Biomechanics of ossiculoplasty, CME Bulletin Otorhinolaryngology Head and Neck Surgery, 7, 2003, p64 - 66Journal Article, 2003, URL
- DJ Kelly, PJ Prendergast, A Mechanobiological analysis of osteochondral defect repair, Transactions of the 50th Annual Meeting of the Orthopaedic Research Society, San Francisco, California, 2004, 2004Poster, 2004
- M Moretti, D Wendt, S C Dickinson, T J Sims, A P Hollander, D J Kelly, P J Prendergast, M Heberer, I Martin, Effects of in vitro pre-culture on the in vivo development of human engineered cartilage in an ectopic model, Tissue Engineering, 11, (9-10), 2005, p1421 - 1428Journal Article, 2005, DOI , URL
- Kelly, D.J. and O'Brien, F.J. and Prendergast, P.J., A Short History of Bioengineering Research in Ireland, Journal of Biomechanical Engineering, 140, (2), 2018, p021005Journal Article, 2018, DOI , URL
- Kelly, DJ, Prendergast PJ, Mechano-regulation of stem cell differentiation and tissue regeneration in osteochondral defects, Journal of Biomechanics, 38, 2005, p1413 - 1422Journal Article, 2005
- Nowlan, NC, Prendergast PJ, Evolution of mechanoregulation of bone growth will lead to non-optimal bone phenotypes, Journal of Theoretical Biology, 235, (3), 2005, p408 - 418Journal Article, 2005, DOI , URL , TARA - Full Text
- Scannell, PT, Prendergast PJ, Simulation of changes in bone around a hip prosthesis, Engineers Journal, 59, 2005, p319 - 324Journal Article, 2005
- McGarry JG, Klein-Nulend, J, Prendergast, PJ, The effect of cytoskeletal modulation of pulsatile fluid flow-induced Nitric Oxide and Prosteoglandin E2 release in osteocytes and osteoblasts, Biochemical and Biophysical Research Communications, 330, 2005, p342 - 348Journal Article, 2005
- Murphy, LA, Prendergast, PJ, Acromion-fixation of glenoid components in total shoulder arthroplasty, Journal of Biomechanics, 38, (8), 2005, p1702 - 1711Journal Article, 2005, DOI , URL
- Andreykiv, A, Prendergast, PJ, van Keulen, F, Swieszkowski, W, Rozing, PM, Bone ingrowth simulation for concept glenoid component design, Journal of Biomechanics, 38, (5), 2005, p1023 - 1033Journal Article, 2005, DOI , URL
- Lally, C, Dolan, F, Prendergast, PJ, Cardiovascular stent design and blood vessel stress: a finite element analysis, Journal of Biomechanics, 38, (8), 2005, p1574 - 1581Journal Article, 2005, DOI , URL
- Prendergast, PJ, Taylor, D, The design of intramedullary prostheses to prevent bone loss: predictions based on damage-stimulated remodelling, Journal of Biomedical Engineering, 14, (6), 1992, p499-506Journal Article, 1992, DOI , URL
- Prendergast, PJ, An analysis of theories in biomechanics, Engineering Transactions, 49, 2001, p117-133Journal Article, 2001
- Prendergsast, PJ, The bioengineering design forum: developing an innovation network, Industry and Higher Education, 11, 1997, p116-9Journal Article, 1997
- Prendergast, PJ, Huiskes, R, Microdamage and osteocyte-lacuna strain in bone: a microstructural finite element analysis, Journal of Biomechanical Engineering, 118, (2), 1996, p240-6Journal Article, 1996, DOI , URL
- McNamara, BP, Taylor, D, Prendergast PJ, Computer prediction of adaptive bone-remodelling around noncemented femoral prostheses: the relationship between damage-based and strain-based algorithms, Medical Engineering and Physics, 19, 1997, p454-63Journal Article, 1997
- Prendergast, PJ, van Driel, WD, Kuiper, JH, A comparison of finite element codes for the solution of biphasic poroelastic problems, Journal of Engineering in Medicine; Proceedings of the Institution of Mechanical Engineers, Part H 210, 1996, p124-130Journal Article, 1996, URL
- Prendergast, PJ, Huiskes, R, Finite element analysis of fibrous tissue morphogenesis: a study of the 'osteogenic index' using a biphasic approach, Mechanics of composite materials, 32, 1996, p209-18Journal Article, 1996
- Lacroix, D, Prendergast, PJ, Three-dimensional simulation of fracture repair in the human tibia, Computer Methods in Biomechanics and Biomedical Engineering, 5, 2002, p369 - 376Journal Article, 2002
- Prendergast, PJ, Monaghan, J, Taylor, D, Materials selection in the artificial hip joint using finite element stress analysis, Clinical Materials, 4, (2-3), 1989, p361-76Journal Article, 1989, DOI , URL
- Prendergast, PJ, Toland, SJ, Corrigan, JP, Finite element analysis and experimental testing of external fixator frame designs, Journal of Engineering in Medicine, Proceedings of the Institution of Mechanical Engineers, Part H, 208, 1994, p103-10Journal Article, 1994, DOI , URL
- Lennon, AB, Prendergast, PJ, Evaluation of cement stresses in finite element analyses of cemented orthopaedic implants, Journal of Biomechanical Engineering, 123, (6), 2001, p623-628Journal Article, 2001, DOI
- Prendergast, PJ, Kelly, D, Rafferty, M, Blayney AW, The effect of ventilation tubes on stresses and vibration motion in the tympanic membrane: a finite element analysis, Clinical Otolaryngology, 24, 1999, p542-48Journal Article, 1999
- Kelly, DJ, Prendergast, PJ, Blayney, AW, The effect of prosthesis design on the vibration of reconstructed ossicular chain: a comparative finite element analysis of four prostheses, Otology and Neurotology , 24, 2003, p11-19Journal Article, 2003
- Lacroix, D, Prendergast, PJ, Stress analysis of glenoid component design for shoulder arthroplasty, Journal of Engineering in Medicine, Proceedings of the Institution of Mechanical Engineers, Part H - 211, 1997, p467-74Journal Article, 1997
- Murphy, LA, Prendergast, PJ, Resch, H, Structural analysis of an offset-keel design glenoid component compared to a centre-keel design, Journal of Shoulder and Elbow Surgery, 10, 2001, p568-679Journal Article, 2001
- Prendergast, PJ, Lally, C, Daly, S, Lee, TC, Quinn, D, Dolan, F, Analysis of prolapse in cardiovascular stents: a constitutive equation for vascular tissue and finite element modelling, Journal of Biomechanical Engineering , 125, 2003, p692-699Journal Article, 2003
- Culleton, TP, Prendergast, PJ, Taylor, D, Fatigue failure in the cement mantle of an artificial hip joint, Clinical Materials, 12, (2), 1993, p95-102Journal Article, 1993, DOI , URL
- Murphy, BP, Prendergast, PJ, Measurement of non-linear micro-crack accumulation rates in polymethylmethacrylate bone cement under cyclic loading, Journal of Materials Science: Materials in Medicine, 10, 1999, p779-81Journal Article, 1999
- Maher, SA, Prendergast, PJ, Reid, AJ, Waide, DV, Toni, A, Design and validation of a machine for reproducible precision insertion of femoral hip prostheses for pre-clinical testing, Journal of Biomechanical Engineering, 123, 2000, p203-7Journal Article, 2000
- Murphy, BJ, Prendergast, PJ, The relationship between stress, porosity and on-linear damage accumulation in acrylic bone cement, Journal of Biomedical Biomaterials Research, 59, 2001, p646-654Journal Article, 2001
- Prendergast, PJ, Murphy, BP, Taylor, D, Fatigue testing of orthopaedic bone cement: a comment on Cristofolini et al., Fatigue and Fracture of Engineering Materials and Structures, 25, 2002, p315 - 316Journal Article, 2002
- Prendergast, PJ, Maher, SA, Issues in pre-clinical testing of implants, Journal of materials processing technology, 118, 2001, p337-342Journal Article, 2001
- Prendergast, PJ, Lee, TC, On a wing and a prayer: the biomechanics of the Rev. Dr. Samuel Haughton (1821-1897), Journal of the Irish Colleges of Physicians and Surgeons, 28, 1999, p38-43Journal Article, 1999
- Prendergast, PJ, Lee, TC, Walking on water: The biomechanics of Professor MA MacConaill (1921-1987), Journal of the Irish Colleges of Physicians and Surgeons, 175, 2006, p69 - 73Journal Article, 2006
- McNamara, LM, Prendergast, PJ, Perforation of cancellous bone trabeculae by damage-stimulated remodelling at resorption pits: a computational analysis, European Journal of Morphology, 42, (1-2), 2005, p99 - 109Journal Article, 2005, DOI , URL
- Britton, JR, Prendergast, PJ, Preclinical testing of femoral hip components: an experimental investigation with four prostheses, Journal of Biomechanical Engineering, 127, 2005, p872 - 880Journal Article, 2005, DOI , URL
- Moretti, M, Wendt, D, Dickinson, S, Hollander, AP, Kelly, DJ, Prendergast, PJ, Herber, M, Martin, I, Effects of in vitro pre-culture on the in vivo development of human engineered cartilage, Tissue Engineering, 11, (9-10), 2005, p1421 - 1428Journal Article, 2005, DOI , URL
- European Journal of Morphology, 42, (2005), 1 - 2p, Lee, TC, Prendergast, PJ , [Guest Eds.], Editorial: Microdamage in BoneJournal, 2005
- Meccanica - Special Issue on "Mechanics of Tissues and Implants", 37, 4/5, (2002), 315 - 488p, Prendergast, PJ, Contro, R, [Guest Eds.]Journal, 2002
- Prosthesis fixation for orthopaedics in, editor(s)Webster, JE , Wiley Encyclopaedia of Medical Devices and Instrumentation, New Jersey, John Wiley & Sons, 2006, pp192 - 198, [Prendergast, PJ]Book Chapter, 2006
- Stents in, editor(s)Akay M , Wiley Encyclopaedia of Biomedical Engineering, John Wiley & Sons, 2007, pp3345 - 3355, [Lally C, Prendergast PJ, Kelly D]Book Chapter, 2007, URL
- Prina-Mello A, Farrell E, Prendergast PJ, Campbell V, Coey JMD, Influence of Strong Static Magnetic, Bioelectromagnetics, 27, (1), 2006, p35 - 42Journal Article, 2006, URL
- McNamara, LM, Ederveen, AGH, Lyons, CG, Weinans, H, Price C, Schaffler, MB, Prendergast, PJ, Strength of cancellous bone trabecular tissue from normal, ovariectomized and drug-treated rats over the course of ageing, Bone, 39, (2), 2006, p392 - 400Journal Article, 2006, DOI , URL
- McNamara LM, Van der Linden JC, Weinans H, Prendergast PJ, Stress-concentrating effect of resorption lacunae in trabecular bone, Journal of Biomechanics, 39, (4), 2006, p734 - 741Journal Article, 2006, DOI , URL
- Simon P. Wilson, B.A.O. McCormack, C.D. Walsh and P.J. Prendergast, A statistical analysis of microcrack accumulation in PMMA under fatigue loading: applications to orthopaedic implant fixation, International Journal of Fatigue, 20, (3), 1998, p581 - 593Journal Article, 1998, DOI
- McNamara LM, van der Linden J, Weinans H, Prendergast PJ, Stress-concentrating effect of resorption lacunae in trabecular bone, Journal of Biomechanics, 39, (4), 2006, p734 - 741Journal Article, 2006, DOI , URL
- Kelly DJ, Prendergast PJ, Prediction of optimal mechanical properties for a scaffold used in osteochondral defect repair, Tissue Engineering, 12, (9), 2006, p2509 - 2519Journal Article, 2006, DOI , URL , TARA - Full Text
- McNamara LM, Prendergast PJ, Schaffler MB, Bone tissue material properties are altered during osteoporosis, Journal of Musculoskeletal and Neuronal Interactions, 5, (4), 2005, p342 - 343Journal Article, 2005, URL , TARA - Full Text
- Stolk, J, Verdonschot, N, Murphy, BP, Prendergast, PJ, Huiskes, R, Finite element simulation of anisotropic damage accumulation and creep in acrylic bone cement, Engineering Fracture Mechanics, 71, 2003, p513-528Journal Article, 2003
- Kelly, DJ, Blayney, AW, Prendergast, PJ, Biomechanics of ossiculoplasty, CME Bulletin Otorhinolaryngology Head and Neck Surgery, 7, 2003, p64 - 66Journal Article, 2003, TARA - Full Text
- Swieszkowski, W, Bednarz, P, Prendergast, PJ, Contact stresses in the glenoid component in total shoulder arthroplasty, Journal of Engineering in Medicine; Proceedings of the Institution of Mechanical Engineers, Part H - 217, 2003, p49-57Journal Article, 2003
- Murphy, BP, Prendergast, PJ, Multi-axial fatigue of orthopaedic bone cement - experiments with tubular specimens, Journal of Materials Science: Materials in Medicine, 14, 2003, p857-861Journal Article, 2003
- Britton, JR, Walsh, LA, Prendergast, PJ, Mechanical simulation of muscle loading on the proximal femur: analysis of cemented femoral component migration with and without muscle loading , Clinical Biomechanics, 18, 2003, p637-646Journal Article, 2003
- Lennon, AB, McCormack, BAO, Prendergast, PJ, The relationship between cement fatigue damage and implant surface finish in proximal femoral prostheses, Medical Engineering and Physics, 25, (10), 2003, p833-841Journal Article, 2003, DOI
- Prina Mello, A, Volkov, Y, Delleher, D, Prendergast, PJ, Comparative locomotory behavious of T lymphocytes and T lymphoma cells on flat and grooved surfaces, Annals of Biomedical Engineering, 31, 2003, p1106-1113Journal Article, 2003
- Kelly, DJ, Prendergast, PJ, Mechanical properties of the cartilage component in tissue-engineered cartilage constructs determined by poroelastic finite element modelling, Medical and Biological Engineering and Computing, 2003Journal Article, 2003
- Moretti, M, Barron, V, Prina Mello, A, Reid, AJ, Prendergast, PJ, Endothelial cell alignment on cyclically-stretched silicone surfaces, Journal of Materials Science: Materials in Medicine, 15, 2004, p1159 - 1164Journal Article, 2004
- E. Farrell., F.J. O'Brien., P. Doyle., J. Fischer., I. Yannas., B. O'Connell., P.J. Prendergast & V.A. Campbell , A collagen-glycosaminoglycan scaffold supports adult rat mesenchymal stem cell differentiation along osteogenic and chondrogenic routes., Tissue Engineering, 12, (3), 2006, p459 - 468Journal Article, 2006, DOI , URL
- Prendergast, PJ, Finite element analysis in tissue mechanics and orthopaedic implant design, Clinical Biomechanics, 12, 1997, p343-368Journal Article, 1997
- McNamara LM, Prendergast PJ, Bone remodelling algorithms incorporating both strain and microdamage stimuli , Journal of Biomechanics, 40, (6), 2007, p1381 - 1391Journal Article, 2007, DOI , URL
- Prina-Mello A, Farrell E, Prendergast PJ, Campbell V, Coey JMD , Influence of strong static magnetic fields on primary cortical neurons , Bioelectromechanics, 27, 1, (Jan), 2006, p35 - 42Journal Article, 2006, DOI
- Farrell, E., O'Brien, F., Prendergast, P. J., Campbell, V. A., Mesenchymal stem cells and bioengineering, Journal of Anatomy, 205, (6), 2004, p504 - 536Journal Article, 2004, URL
- Hardiman DA, O'Brien FJ, Prendergast PJ, Croke DT, Staines A, Lee TC, Tracking the changes in uploaded bone: Morphology and gene expression, European Journal of Morphology, 42, (4-5), 2005, p208 - 216Journal Article, 2005, DOI , URL
- Combining mechanoregulation algorithms for bone remodeling and tissue differentiation in, editor(s)Gonzalez Y , Bioengineering Modelling and Computer Simulations, Madrid, CIMNE Editorial, 2007, pp238 - 248, [Prendergast PJ]Book Chapter, 2007
- O'Brien, FJ, Waller, MA, Harley, BA, Yannas, IV, Gibson, LJ, Prendergast, PJ, The effect of pore size on permeability and cell attachment in collagen scaffolds for tissue engineering, Technology and Healthcare, 15, (1), 2007, p3 - 17Journal Article, 2007, URL
- Farrell, E, Byrne, EM, Fischer, J, O'Brien, FJ, O'Connell, BC, Prendergast, PJ, Campbell, VA, A comparison of the osteogenic potential of adult rat mesenchymal stem cells cultured in 2-D and on 3-D collagen glycosaminoglycan scaffolds., Technology and Healthcare, 15, (1), 2007, p19 - 31Journal Article, 2007, URL , TARA - Full Text
- Lennon, AB, Britton, JR, MacNiochaill, R, Byrne, D, Prendergast, PJ, Predicting revision risk for aseptic loosening of femoral components in total hip arthroplasty in individual patients - a finite element study, Journal of Orphopaedic Research, 25, (6), 2007, p779 - 788Journal Article, 2007, DOI , URL
- Prendergast, PJ, Pérez, MA, Random-walk models of cell dispersal included in mechano-biological simulations of tissue differentiation, Journal of Biomechanics, 40, (10), 2007, p2244 - 2253Journal Article, 2007, DOI , URL
- Marenzana, M, Kelly, DJ, Prendergast, PJ, Brown, RA, A collagen-based interface construct for the assessment of cell-dependent mechanical integration of tissue surfaces, Cell and Tissue Research, 327, (2), 2007, p293 - 300Journal Article, 2007, DOI , URL
- O'Brien, F.J.; Harley, B.A.; Waller, M.A.; Yannas, I.V; Gibson, L.J and Prendergast, P.J., The effect of pore size on permeability and cell attachment in collagen scaffolds for tissue engineering., Technology and Healthcare , 15, (1), 2007, p3 - 17Journal Article, 2007, URL , TARA - Full Text
- Prendergast PJ, Computational modelling of cell and tissue mechanoresponsiveness, Gravitational and Space Biology, 20, (2), 2007, p43 - 49Journal Article, 2007, URL
- McGarry, JG, Maguire, P, Prendergast, PJ, Campbell, VA, O'Connell, BC, Jarvis, SP, Stimulation of nitric oxide mechanotransduction in single osteoblasts using atomic force microscopy, Journal of Orthopaedic Research, 26, (4), 2008, p513 - 521Journal Article, 2008, DOI , URL
- Andreykiev, A, van Keulen, F, Prendergast, PJ, Simulation of fracture healing incorporating mechanoregulation of tissue differentiation and dispersal / proliferation on cell populations, Biomechanics and Modelling in Mechanobiology, 7, 2008, p443 - 461Journal Article, 2008
- Byrne, DP, Lacroix, D, Kelly, DJ, Plannel, J, Prendergast, PJ, Simulation of tissue differentiation in a scaffold as a function of porosity, Young's modulus, and dissolution rate of a scaffold: application of mechanobiological models in tissue engineering, Biomaterials, 28, (36), 2007, p5544 - 5554Journal Article, 2007, DOI , URL
- Nowlan, NC, Murphy, P, Prendergast, PJ, Mechanobiology of embryonic limb development, Annals of the New York Academy of Sciences, 1101, 2007, p389 - 411Journal Article, 2007, DOI , URL , TARA - Full Text
- Jeffers, JRT, Browne, M, Lennon, AB, Prendergast, PJ, Taylor, M, Cement mantle fatigue failure in total hip replacement: experimental and computational testing, Journal of Biomechanics, 40, (7), 2007, p1525 - 1533Journal Article, 2007, DOI , URL
- Automated generation of 3D bone models from planar X-ray images for patient-specific finite element modeling applications in, editor(s)JMRS Tavares, RM Natal Jorge , Computational Modelling of Objects Represented in Images, London, Taylor & Francis Group, 2007, pp191 - 195, [Galibarov, PE, Lennon, AB, Prendergast, PJ]Book Chapter, 2007
- Combining mechanoregulation algorithms for bone remodelling and tissue differentiation in, editor(s)Y González, M Cerrolaza , Bioengineering Modelling and Computer Simulation, Barcelona, 2007, pp238 - 248, [Prendergast, PJ]Book Chapter, 2007
- Foolen J., van Donkelaar C., Nowlan N., Murphy P., Huiskes R. and Ito K., Collagen orientation in periosteum and perichondrium is aligned with preferential directions of tissue growth., Journal of Orthopaedic Research, 26, (9), 2008, p1263 - 1268Journal Article, 2008, DOI , URL
- Nowlan, N.C. and Prendergast P.J., Evolution of Mechanoregulation of Bone Growth Will Lead to Non-optimal Bone Phenotypes, Journal of Theoretical Biology, 235, (3), 2005, p408 - 418Journal Article, 2005, DOI
- Maguire P, Kilpatrick JI, Kelly G, Prendergast PJ, Campbell VA, O'Connell BC, Jarvis SP, Direct mechanical measurement of geodesic structures in rat meseenchymal stem cells, Human Frontiers Science Program Journal, 1, (3), 2007, p181 - 191Journal Article, 2007, DOI , URL
- Prendergast, PJ, Brown, SH, Britton, JR, Research programmes that promote novel, ambitious, unconventional, and high risk research: an analysis, Industry and Higher Education, 22, (4), 2008, p215 - 221Journal Article, 2008
- Kanichai M, Ferguson D, Prendergast PJ, Campbell VA, Hypoxia promotes chondrogenesis in rat mesenchymal stem cells: A role for AKT and hypoxia-inducible factor (HIF)-1, Journal of Cellular Physiology, 216, (3), 2008, p708 - 715Journal Article, 2008, DOI
- MacNiocaill RF, Guerin S, Britton JR, Lennon AB, Prendergast PJ, Kenny PJ, Experimental investigation of negative pressure intrusion techniques of acetabular cementation in total hip arthroplasty, Acta Orthopaedica Belgica, 74, (1), 2008, p64 - 71Journal Article, 2008, URL
- Boccaccio A, Prendergast PJ, Pappalettere C, Kelly DJ, Tissue differentiation and bone regeneration in an osteotomized mandible: a computational analysis of the latency period, Medical and Biological Engineering and Computing, 46, (3), 2008, p283 - 298Journal Article, 2008, DOI , URL , TARA - Full Text
- Nowlan N, Murphy P, Prendergast PJ, Dynamic pattern of mechanical stimulation promotes ossification in avian embryonic long bones, Journal of Biomechanics, 41, (3), 2008, p249 - 258Journal Article, 2008, DOI , URL , TARA - Full Text
- McMahon, L.A. , Prendergast, P.J. , Campbell, V.A., A comparison of the involvement of p38, ERK1/2 and PI3K in growth factor-induced chondrogenic differentiation of mesenchymal stem cells, Biochemical and Biophysical Research Communications , 368, (4), 2008, p990 - 995Journal Article, 2008, DOI , URL
- Keeling, P, Prendergast, P.J., Lennon, A.B., Kenny, P.J., Cement-in-cement revision hip arthroplasty: an analysis of clinical and biomechanical literature, Archives of Orthopaedic Trauma Surgery, 128, (10), 2008, p1193 - 1199Journal Article, 2008, DOI
- Mulvihill BM, McNamara LM, Prendergast PJ., Loss of trabeculae by mechano-biological means may explain rapid bone loss in osteoporosis., Journal of the Royal Society - Interface, 5, 2008, p1243 - 1253Journal Article, 2008, DOI , URL , TARA - Full Text
- Prendergast, PJ , Finite element models in tissue mechanics and orthopaedic implant design , Journal of Biomechanics , 12, (6), 1994, p343-366Journal Article, 1994, DOI , URL
- European Society of Biomechanics, Lennon AB, Prendergast PJ (Eds.) , Finite Element Modelling in Biomechanics and Mechanobiology,, Dublin, Trinity College Dublin, European Society of Biomechanics, 2007, i-xiv + 1-212ppBook, 2007
- Prendergast, P.J. , Computational modelling of cell and tissue mechanoresponsiveness', Gravitational and Space Biology, 20, (2), 2007, p43-49Journal Article, 2007, URL
- Pérez, M.A. and Prendergast, P.J. , Random-walk models of cell dispersal included in mechano-biological simulations of tissue differentiation', Journal of Biomechanics, 40, (10), 2007, p2244 - 2253Journal Article, 2007, DOI , URL
- McMahon, L.A., Reid, A.J., Campbell, V.A. & Prendergast, P.J. , Regulatory Effects of Mechanical Strain on the Chondrogenic Differentiation of MSCs in a Collagen-GAG Scaffold: Experimental and Computational Analysis , Annals of Biomedical Engineering, 36, (2), 2008, p185-194Journal Article, 2008, DOI , URL
- Vard, J.P., Kelly, D.J., Blayney, A.W. and Prendergast, P.J. , The influence of ventilation tube design on the magnitude of stress imposed at the implant/tympanic membrane interface, Medical Engineering and Physics, 30, (2), 2008, p154-163Journal Article, 2008, DOI , URL , TARA - Full Text
- Lennon, A.B., Britton, J.R., Mac Niocaill, R.F., Byrne, D.P., Kenny, P.J., Prendergast, P.J., Predicting revision risk for aseptic loosening of femoral components in total hip arthroplasty in individual patients - a finite element study, Journal of Orthopaedic Research, 25, (6), 2007, p779-788Journal Article, 2007, DOI , URL
- P. Maguire, J.I. Kilpatrick, G. Kelly, P.J. Prendergast, V.A. Campbell, B.C. O'Connell and S.P. Jarvis, Direct mechanical measurement of geodesic structures in rat mesenchymal stem cells', Human Frontiers Science Program Journal, 1, (3), 2007, 181-191Journal Article, 2007, DOI , URL
- D.J. Kelly, A. Crawford, S.C. Dickinson, T.J. Sims, A.P. Hollander, P.J. Prendergast and P.V. Hatton, Biochemical Markers of the Mechanical Quality of Engineered Hyaline Cartilage, Journal of Materials Science: Materials in Medicine, 18, (2), 2007, p273-281Journal Article, 2007, DOI , URL , TARA - Full Text
- J.G. McGarry, P. Maguire, P.J. Prendergast, V.A. Campbell, B.C. O'Connell and S.P. Jarvis, Stimulating Nitric Oxide response in single osteoblasts using atomic force microscopy', Journal of Orthopaedic Research, 26, (4), 2008, p513-520Journal Article, 2008, DOI , URL
- P.J. Prendergast, Combining mechanoregulation algorithms for bone remodelling and tissue differentiation, International Center for Numerical Methods in Engineering, Barcelona, edited by Y. González and M. Cerrolaza , 2007, pp238-248Conference Paper, 2007, URL
- D.P. Byrne, D. Lacroix, D.J. Kelly and P.J. Prendergast, The effect of loading on bone regeneration in a regular structured scaffold, Proceedings of the 3rd International Conference on Computational Bioengineering, 3rd International Conference on Computational Bioengineering, Universidad Central de Venezuela, Caracas , edited by M. Cerrolaza , 2007, pp215-220Conference Paper, 2007
- B.M. Mulvihill, L.M. McNamara and P.J. Prendergast, The effect of patient-specific bone remodelling rates on remodelling/repair in trabecular bone, Proceedings of the 3rd International Conference on Computational Bioengineering, 3rd International Conference on Computational Bioengineering, Universidad Central de Venezuela, Caracas, edited by M. Cerrolaza , 2007, pp237-242Conference Paper, 2007
- N. Nowlan, P. Murphy and P.J. Prendergast, Mechanical stimuli resulting from embryonic muscle contractions promote avian periosteal bone collar formation', Summer Bioengineering Conference,, Colorado , American Society of Mechanical Engineers, 2007Conference Paper, 2007
- A.J.F. Stops, L.A. McMahon, D. O'Mahoney, P.E. McHugh and P.J. Prendergast, A finite element prediction of cellular strain in a GAG-scaffold', 2007 Summer Bioengineering Conference, Colorado, American Society of Mechanical Engineers, 2007Conference Paper, 2007
- B.M. Mulvihill, L.M. McNamara and P.J. Prendergast, Increases in elastic modulus of trabecular bone tissue leads to more rapid perforation of trabecular osteoporotic bone' , 2007 Summer Bioengineering Conference, Colorado , American Society of Mechanical Engineers, 2007Conference Paper, 2007
- P.J. Prendergast and A.B. Lennon, An introduction to the workshop on finite element modelling in biomechanics and mechanobiology, Finite Element Modelling in Biomechanics and Mechanobiology European Society of Biomechanics, Dublin, Ireland , 2007, pp1-4Conference Paper, 2007, URL
- Mulvihill, BM, Prendergast PJ, An algorithm for bone mechanoresponsiveness: implementation to study the effect of patient-specific cell mechanosensitivity on trabecular bone loss, Computer Methods in Biomechanics and Biomedical Engineering, 11, 2008, p443 - 451Journal Article, 2008, DOI
- Nowlan NC, Prendergast PJ., Evolution of mechanoregulation of bone growth will lead to non-optimal bone phenotypes, Journal of Theoretical Biology, 235, (3), 2005, p408-18Journal Article, 2005, DOI , URL , TARA - Full Text
- Nowlan, N.C. , Murphy P. and Prendergast, P.J., Mechanical Stimuli Resulting From Embryonic Muscle Contractions Promote Avian Periosteal Bone Collar Formation, Proceedings of the 2007 Summer Bioengineering Conference of the American Society of Mechanical Engineering, 2007 Summer Bioengineering Conference of the American Society of Mechanical Engineering, American Society of Mechanical Engineering, 2005, pp833-834Conference Paper, 2005
- Nowlan, N.C. , Murphy P. and Prendergast, P.J., The characterisation of mechanical stresses in the growing avian embryonic limb, Proceedings of the 5th World Congress of Biomechanics, 5th World Congress of Biomechanics, 2006Conference Paper, 2006
- Nowlan, N.C., Murphy P. and Prendergast, P.J., The calculation of mechanical stresses in the growing avian embryonic limb using optical projection tomography, Proceedings of the 2006 Summer Bioengineering Conference of the American Society of Mechanical Engineering, Summer Bioengineering Conference of the American Society of Mechanical Engineering, 2006Conference Paper, 2006
- Nowlan, N.C. , Murphy P. and Prendergast, P.J. , The influence of mechanical forces in the growing embryonic limb, Proceedings of the 52 nd Annual Meeting of the Orthopaedic Research Society , 52 nd Annual Meeting of the Orthopaedic Research Society , Orthopaedic Research Society , 2006, pp31Conference Paper, 2006
- Nowlan, N.C., Murphy P. and Prendergast, P.J, Computation of stresses in the growing embryonic chick limb, Proceedings of the 2 nd International Conference on Computational Bioengineering , 2nd International Conference on Computational Bioengineering , edited by Rodrigues, et al., , 2, IST Press. Lisbon., 2005, pp861-872Conference Paper, 2005
- A scheme for investigating the evolution of bone remodelling laws in, Book of Abstracts of the International Workshop for Numerical Models of Bone Adaptation and Repair , International Workshop for Numerical Models of Bone Adaptation and Repair , 2004, pp22 - [Nowlan, N.C. and Prendergast, P.J. ]Book Chapter, 2004
- McMahon LA, Campbell VA, Prendergast PJ, Involvement of stretch-activated ion channes in strain-regulated glycosaminoglycan synthesis in mesenchymal stem cell-seeded 3D scaffolds, Journal of Biomechanics, 41, 2008, p2055 - 2059Journal Article, 2008, DOI , URL
- Kearney EM, Prendergast PJ, Campbell VA, Mechanisms of strain-mediated mesenchymal stem cell apoptosis, Journal of Biomechanical Engineering, 130, 2008Journal Article, 2008, DOI
- Kearney EM, Farrell E, Prendergast PJ, Campbell VA, Mechanobiology of a tensile strain-induced osteogenic response in mesenchymal stem cells, Annals of Biomedical Engineering, 2008Journal Article, 2008
- Stops AJF, McMahon LA, O'Mahoney D, Prendergast PJ, McHugh PE, A finite element prediction of the strain on cells in a highly porous collagen glycosaminoglycan scaffold, Journal of Biomechanical Engineering, 130, 2008, p061001.1 - 061001.11Journal Article, 2008
- Prendergast PJ, "May the force be with you": 14th Samuel Haughton Lecture, Irish Journal of Medical Science, 177, 2008, p289 - 292Journal Article, 2008, DOI
- Nowlan, N., Prendergast P.J. and Murphy, P., Identification of Mechanosensitive Genes during Embryonic Bone Formation. , PLoS Computational Biology, 4, (12), 2008, pe1000250-Journal Article, 2008, TARA - Full Text
- McMahon LA, O'Brien FJ, Prendergast PJ, Biomechanics and mechanobiology in osteochondral tissues, Regenerative Medicine, 3, 2008, p743 - 759Journal Article, 2008, DOI
- Karen A. Roddy, Niamh C Nowlan, Patrick J. Prendergast, and Paula Murphy, 3D representation of the developing chick knee joint: a novel approach integrating multiple components, Journal of Anatomy, 214, (3), 2009, p374 - 387Journal Article, 2009, DOI , URL
- Scannell PT, Prendergast PJ, Cortical and interfacial bone changes around a non-cemented hip implant: simulations using a combined strain/damage remodelling algorithm, Medical Engineering and Physics, 31, 2009, p477 - 488Journal Article, 2009, DOI
- Checa, S, Prendergast, PJ, A mechanobiological model for tissue differentiation that includes angiogenesis: a lattice-based modeling approach, Annals of Biomechanical Engineering, 37, 2009, p129 - 145Journal Article, 2009, DOI
- Andreykiv, A, van Keulen, F, Prendergast, PJ, Computational mechanobiology to study the effect of surface geometry on peri-implant tissue differentiation, Journal of Biomechanical Engineering, 130, 2008, p051015.1 - 051015.11Journal Article, 2008
- Lennon, A.B. and Prendergast, P.J. , The cement-bone interface: is it susceptible to damage adaptive remodeling?, IFMBE Proceedings, 4th European Congress For Medical and Biomedical Engineering, Antwerp, Belgium, 23-27 November 2008, edited by Vander Sloten, J, Verdonck, P., Nyssen, M., Haueisen, J. , 22, Springer-Verlag, 2008, pp1990 - 1993Conference Paper, 2008, DOI
- De Santis, G., McGarry, J.G., Lennon, A.B., Prendergast, P.J. , Finite element models of AFM indentation of adherent cell , Proceedings of the 2007 Summer Workshop of the European Society of Biomechanics, Finite Element Modelling in Biomechanics and Mechanobiology , Trinity College Dublin, 26-28 August 2007, edited by Lennon, A.B., Prendergas, P.J. , Trinity Centre for Bioengineering, Trinity College Dublin, Ireland, 2007, pp187 - 188Conference Paper, 2007
- Galibarov, P.E., Lennon, A.B., Prendergast, P.J. , Patient-specific finite element models based on radiographs for pre-operative planning , Proceedings of the 2007 Summer Workshop of the European Society of Biomechanics, Finite Element Modelling in Biomechanics and Mechanobiology , Trinity College Dublin, 26-28 August 2007, edited by Lennon, A.B., Prendergast, P.J. , Trinity Centre for Bioengineering, Trinity College Dublin, Ireland, 2007, pp201 - 202Conference Paper, 2007
- Lennon, A.B, Britton, J.R., MacNicoill, R.F., Kenny, P.J., Prendergast, P.J , Can patient-specific finite element simulation be used for pre-operative assessment of early revision risk? , Engineers and Surgeons: Joined at the Hip: Refining future strategies in total hip replacement, One Great Georges St., London, U.K., 19-21 April 2007, Institution of Mechanical Engineers , 2007, pp21 - 24Conference Paper, 2007
- Galibarov, P.E., Lennon, A.B., Prendergast, P.J., Automated generation of 3D bone model from planar X-ray image for patient-specific finite element modelling, Proceedings of the International Symposium CompIMAGE 2006 , Computational Modelling of Objects Represented in Images. Fundamentals, Methods and Applications, Coimbra, Portugal , 20-21 October 2006 , edited by J. M. R.S. Tavares and R.M. Natal Jorge , Taylor and Francis Group, London , 2007, pp191 - 195Conference Paper, 2007
- Prendergast P.J., Britton J.R., Scannell P.T., Lennon A.B. , Failure of biomaterials in implant fixation , Proceedings of the 16th European Conference on Fracture , Fracture of Nano and Engineering Materials and Structures , Greece , 2006, edited by E.E. Gdoutos , Springer, Berlin, ISBN 978-1-4020-4971-2 , 2006, pp1031 - 1032Conference Paper, 2006, DOI
- Lennon, A.B., Murphy, B.P., and Prendergast, P.J. , Modelling fatigue failure of PMMA specimens as a stochastic process , Computer Methods in Biomechanics & Biomedical Engineering-4, Rome, Italy, 2001, edited by J. Middleton, M.L. Jones, N.G. Shrive, and G.N. Pande , 2001, ppCDROMConference Paper, 2001
- A.B. Lennon, P.J. Prendergast(ed.), Finite Element Modelling in Biomechanics and Mechanobiology , Proceedings of the 2007 Summer Workshop of the European Society of Biomechancis , 26-28 August 2007, Trinity Centre for Bioengineering: Dublin ISBN-10: 0-9549593-1-X , 2007, 213 + xiv pProceedings of a Conference, 2007
- Modelling the response of cells to mechanical stimulation in, editor(s)Józef Joachim Telega , Modelling in Biomechanics: Lecture Notes 19 of AMAS, Warsaw, Institute of Fundamental Technological Research, 2004, pp159-189 , [PJ Prendergast, DJ Kelly, JG McGarry.]Book Chapter, 2004
- Byrne, D. P., Lacroix, D., Kelly, D. J., Prendergast, P. J., Modelling cell dispersal in the fracture callus., 16th Congress of the European Society of Biomechanics, Lucerne, Switzerland, edited by July 6th-9th , 2008Conference Paper, 2008
- Byrne, D.P., Lacroix, D., Kelly, D.J., Prendergast, P.J., Finite element modeling of dissolution of a regular structured scaffold for tissue engineering, Proceedings of the 2007 Workshop of the European Society of Biomechanics, Workshop of the European Society of Biomechanics, Dublin, Ireland, 2007, pp134-135Conference Paper, 2007
- Prendergast, P.J., Kelly, D.J., McMahon, L.A., Campbell, V.A. , A computational optimization of scaffolds for tissue engineering of cartilage., Tissue Engineering, Abstracts of 8th TESI Annual Meeting 2005, Shanghai, China, October 22-25, 12, 2006, pp1024Meeting Abstract, 2006
- Byrne, D.P., Prendergast, P.J., Kelly, D.J., Optimisation of scaffold porosity using a stochastic model for cell proliferation and migration in mechanobiological simulations, Journal of Biomechanics , Proceedings of the V World Congress of Biomechanics, Munich, Germany., 39, (1), 2006, ppS413Conference Paper, 2006
- Prendergast, P.J., Kelly, D.J., Perez, M.A., Computational models for the study of the mechanobiology of bone regeneration, European Society of Biomechanics Thematic Workshop: Mechanobiology of Cells and Tissue Regeneration, Leuven, Aug 2005, 2005, pp29-30Conference Paper, 2005
- Reilly, G., Fitzpatrick, D.(ed.), Bioengineering in Ireland , Proceedings of Bioengineering in Ireland , Dublin, 2008, 28 pProceedings of a Conference, 2008
- Buchanan, F., Dunne, N., Orr, J.,(ed.), Bioengineering in Ireland, Proceedings of Bioengineering in Ireland, Dublin, 2007, 75 pProceedings of a Conference, 2007
- McHugh, P.E., O'Mahoney, D., FitzPatrick, D.(ed.), Bioengineering in Ireland , Proceedings of Bioengineering in Ireland , 2006, 106 pProceedings of a Conference, 2006
- McHugh, P.E., O'Mahoney, D., FitzPatrick, D.(ed.), Bioengineering in Ireland , Proceedings of Bioengineering in Ireland , 2006, 82 pProceedings of a Conference, 2006
- Kearney M, Prendergast PJ, Campbell VA, Mechanisms of strain-mediated mesenchymal stem cell apoptosis, Journal of Biomechanical Engineering, 130, (6), 2008, pArticle number 061004Journal Article, 2008, DOI
- Lacroix, D, Plannel, JA, Prendergast PJ, Computer-aided design and finite-element modelling of biomaterial scaffolds for bone tissue engineering , Philosophical Transactions of the Royal Society A: Mathematical, Engineering and Physical Sciences , 367, 2009, p1993 - 2009Journal Article, 2009, DOI
- Medical Engineering & Physics: Special Issue on Finite Element Modelling of Medical Devices, 31, (2009), 419 - 494p, Prendergast, PJ, Lally, C, Lennon, AB, [eds.]Journal, 2009, DOI
- Simms CK & Prendergast PJ (eds.), Perspectives in Design and Bioengineering, Essays in honour of CG Lyons, Trinity College Dublin, Dublin, Trinity Centre for Bioengineering, 2008Book, 2008
- Byrne, E.M., Farrell, E., McMahon, L.A., Haugh, M.G., O'Brien, F.J., Campbell, V.A., Prendergast, P.J., O'Connell, B.C., Gene expression by marrow stromal cells in a porous collagen- glycosaminoglycan scaffold is affected by pore size and mechanical stimulation , Journal of Materials Science: Materials in Medicine, 19, (11-12), 2008, p3455-3463Journal Article, 2008, DOI
- McMahon, L.A., Campbell, V.A., Prendergast, P.J., Involvement of stretch-activated ion channels in strain-regulated glycosaminoglycan synthesis in mesenchymal stem cell-seeded 3D scaffolds , Journal of Biomechanics, 41, (9), 2008, p2055-2059Journal Article, 2008, DOI
- Prendergast, P.J., Lally, C., Lennon, A.B., Finite element modelling of medical devices , Medical Engineering and Physics, 31, (4), 2009, 419Journal Article, 2009, DOI
- Lennon, A.B. , Sources of nonlinearities in biomechanical models, Proceedings of the European Society of Biomechanics Workshop, Finite Element Modelling in Biomechanics and Mechanobiology, Trinity Centre for Bioengineering, Trinity College Dublin, Ireland, 26-28 August , edited by A.B. Lennon and P.J. Prendergast , 2007, pp10-15Conference Paper, 2007
- Galibarov, P, Lennon, A.B., and Prendergast, P.J. , Quantitative assessment of a technique for patient-specific geometry from planar radiographs., 4th European Congress For Medical and Biomedical Engineering 2008, "Engineering for Health", FCCC Antwerp, 23-27 November, International Federation for Medical and Biomedical Engineering, 2008Conference Paper, 2008
- Galibarov, P, Lennon, A.B., and Prendergast, P.J., Retrospective evaluation of an automated method for generating patient-specific FE femur models, 16th Congress of European Society of Biomechanics, Conference, Lucerne, Switzerland, 6-9 July, 2008Conference Paper, 2008
- Lennon, A.B. and Prendergast, P.J. , Assessing the influence of bone remodelling on revision risk of cemented hip prostheses: a patient-specific retrospective study, Proceedings of 17th EORS Meeting, 17th EORS Meeting, Madrid, Spain, 91B, (Suppl), 2008, pp71Conference Paper, 2008, URL
- Lennon, A.B., Mac Niocaill, R.F., Kenny, P.J., Prendergast, P.J. , Assessing the influence of age-dependent bone stiffness on aseptic loosening of cemented total hip stems: an in silico study, Transactions of the Orthopaedic Research Society, San Francisco, USA, 3-5 March, 2008Conference Paper, 2008
- Lennon, A.B., Britton, J.R., MacNiocaill, R.F., Kenny, P.J., Prendergast, P.J., Is high accuracy anatomical modelling necessary for computer simulation of implant loosening in total hip replacement?, Journal of Biomechanics,, 5th World Congress of Biomechanics incorporating 15th Congress of the European Society of Biomechanics, Munich, Germany, 29th July - 4th Aug, 39, (1), 2006, ppS425Conference Paper, 2006
- Lennon A, Britton J, MacNiocaill R, Byrne D, Kenny P, Prendergast PJ, Predicting revision risk in a group of total hip replacement patients using finite element analysis, Proceedings of the American Society of Mechanical Engineers Summer Bioengineering Meeting, Summer Bioengineering Meeting, 52, American Society of Mechanical Engineers, 2006Conference Paper, 2006
- Lennon, A.B.; Britton, J.R.; Vard, J.; Byrne, D. & Prendergast, P.J., Simulation of creep and fatigue damage accumulation can predict clinical performance of total hip femoral components, Annual Symposium Irish Society for Scientific and Engineering Computation, Annual Symposium Irish Society for Scientific and Engineering Computation, Cork, Ireland, 2005, pp19Conference Paper, 2005
- Lennon, A.B.; McCormack, B.A.O. & Prendergast, P.J., Implications of acrylic bone cement porosity for computational modelling of variable failure of cemented joint reconstructions, Proceedings of 14th EORS Meeting, 14th EORS Meeting, Amsterdam, Netherlands, 2004Conference Paper, 2004
- Lennon, A.B. And Prendergast, P.J., Aspects of the mechanical performance of PMMA as an orthopaedic fixation cement, Proceeding of the Ninth Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland, Ninth Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 25-26 January, edited by FitzPatrick, D.P., McCormack, B.A.O., McCormack, D , 2003, ppXXConference Paper, 2003
- Lally, C., Prendergast, P.J., Lennon, A.B., Quinn, D., Dolan, F, Finite element analysis of tissue prolapse within intravascular stents. Calculations using a single repeating unit of a stent and a 3D model of a stent, 13th Conference of the European Society of Biomechanics, Wroclaw, Poland, 2002Conference Paper, 2002
- Lennon, A.B. and Prendergast, P.J., Finite element modelling of the formation of pre-load damage in cement mantles of orthopaedic joint replacements, Summer Bioengineering Conference, Snowbird, Utah, June 27 - July 1, 2001Conference Paper, 2001
- Lennon, A.B. and Prendergast, P.J., Can implant surface finish affect cement damage accumulation around femoral stems in total hip replacement?, Proceedings of 7th Annual Conference of Section of the Royal Academy of Medicine in Ireland, Bioengineering in Ireland, Arklow , Co. Louth, Ireland, 27-28 January , edited by Fitzpatrick, D.P. and Carr, A.J. , Royal Academy of Medicine in Ireland, 2001, 33Conference Paper, 2001
- Lennon, A.B.; Prendergast, P.J.; Lacroix, D.; Revie, I. & Pfleiderer, M., Stress analysis of cement mantle of a polished femoral hip replacement, Proceedings of the 12th Conference of the European Society of Biomechanics, 12th Conference of the European Society of Biomechanics, Dublin, Royal Academy of Medicine in Ireland, 2000, pp189Conference Paper, 2000
- Lennon, A.B., Prendergast, P.J., Whelan, M.P., Kenny, R.P., Cavalli, C, Modelling of temperature history and residual stress generation due to curing in polymethylacrylate, Proceedings of the 12th Conference of the European Society of Biomechanics, 12th Conference of the European Society of Biomechanics, Dublin, Royal Academy of Medicine in Ireland, 2000, pp253Conference Paper, 2000
- Whelan, M.P., Kenny, R.P., Cavalli, C., Lennon, A.B., and Prendergast, P.J., Application of optical fibre Bragg grating sensors to the study of PMMA curing, Proceedings of the 12th Conference of the European Society of Biomechanics, 12th Conference of the European Society of Biomechanics, Dublin, Royal Academy of Medicine in Ireland, 2000, pp252Conference Paper, 2000
- Lennon, A.B., McCormack, B.A.O., and Prendergast, P.J., Issues in modelling mechanical failure of cemented orthopaedic joint replacements., Annual Symposium Irish Society for Scientific and Engineering Computation, Dublin, May , 1998Conference Paper, 1998
- Lennon, A.B. McCormack, B.A.O., and Prendergast, P.J., Calculation of the maximum transient stresses and 'locked-in' residual stresses in bone cement in THR., Bioengineering in Ireland/TUBES Joint Conference, Dundalk, Co. Louth, February , 1998Conference Paper, 1998
- Lennon, A.B., McCormack, B.A.O. & Prendergast, P.J, Structural analysis of physical models of THRs using analytical and finite element methods., Computer Methods in Biomechanics & Biomedical Engineering-2, Barcelona, Spain, 1997Conference Paper, 1997
- Niamh C. Nowlan, Céline Bourdon, Shahragim Tajbakhsh, Gérard Dumas, Patrick J. Prendergast and Paula Murphy, Developing bones are differentially affected by compromised skeletal muscle formation, Bone, 46, 2010, p1275-1285Journal Article, 2010, DOI , TARA - Full Text
- Predictive modelling in mechanobiology: combining algorithms for cell activities in response to physical stimuli using a lattice-modelling approach in, editor(s)M Kuczma, K Wilmanski , Computer Methods in Mechanics, Berlin Heidelberg, Springer-Verlag, 2010, pp423 - 435, [Checa, S, Prendergast, PJ]Book Chapter, 2010
- Computational techniques for selection of biomaterial scaffolds for tissue engineering in, editor(s)P.R. Fernandes, P. Bártolo , Advances on Modelling in Tissue Engineering , Berlin, Springer, 2011, [Checa, S, Sandino, C, Byrne DP, Kelly, DJ, Lacroix, D & Prendergast, PJ]Book Chapter, 2011
- Checa, S, Prendergast, PJ, Effect of cell seeding and mechanical loading on vascularization and tissue formation inside a scaffold: a mechanobiological model using a lattice approach to simulate cell activity, Journal of Biomechanics, 43, (5), 2010, p961-968Journal Article, 2010, DOI , URL
- Mulvihill, BM, Prendergast, PJ, Mechanobiological regulation of the remodelling cycle in trabecular bone and possible pathways for osteoporosis, Clinical Biomechanics, 25, 2010, p491 - 498Journal Article, 2010, DOI , URL
- Sandino, C, Checa, S, Prendergast, PJ, Lacroix, D, Simulation of angiogenesis and cell differentiation in a CaP scaffold subjected to compressive strains using a lattice modeling approach, Biomaterials, 31, (8), 2010, p2446 - 2452Journal Article, 2010, DOI , URL , TARA - Full Text
- Michael Early; Catriona Lally; Patrick J. Prendergast; Daniel J. Kelly, Stresses in peripheral arteries following stent placement: a finite element analysis, Computer Methods in Biomechanics and Biomedical Engineering, 12, (1), 2009, p25 - 33Journal Article, 2009, DOI , URL , TARA - Full Text
- Computational models of tissue differentiation in, editor(s)S. De, F. Guilak, M. Mofrad , Computational Methods in Biomechanics, New York, Springer, 2010, pp353 - 372, [Prendergast, PJ, Checa, S, Lacroix, D]Book Chapter, 2010, DOI
- Khayyeri, H, Checa, S, Tagil, M, Prendergast, PJ, Corroboration of mechanobiological simulations of tissue differentiation in an in vivo bone chamber using a lattice-modelling approach, Journal of Orthopaedic Research, 27, (12), 2009, p1659 - 1666Journal Article, 2009, DOI
- Khayyeri, H, Checa, S, Tagil, M, O'Brien, FJ, Prendergast, PJ, Tissue differentiation in an in vivo bioreactor: in silico investigations of scaffold stiffness, Journal of Materials Science: Materials in Medicine, 21, (8), 2010, p2331-2336Journal Article, 2010, DOI
- Kearney EM, Farrell E, Prendergast PJ, Campbell VA, Tensile strain as a regulator of mesenchymal stem cell osteogenesis., Annals of Biomedical Engineering, 38, (5), 2010, p1767-1779Journal Article, 2010, DOI
- Boyle CJ, Lennon AB, Early M, Kelly DJ, Lally C, Prendergast PJ, Computational simulation methodologies for mechanobiological modelling: a cell-centred approach to neointima development in stents., Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 368, (1921), 2010, p2919-35Journal Article, 2010, DOI , URL , TARA - Full Text
- Nowlan, N. C., Sharpe, J., Prendergast P.J. and Murphy P. , Mechanobiology of Embryonic Skeletal Development: Insights from Animal Models., Birth Defects Research Part C: Embryo Today, 90, (3), 2010, p203-213Journal Article, 2010, DOI
- Karen A. Roddy, Geraldine M. Kelly, Maarten H. van Esc, Paula Murphy, and Patrick J. Prendergast, Dynamic patterns of mechanical stimulation co-localise with growth and cell proliferation during morphogenesis in the avian embryonic knee joint, Journal of Biomechanics, 44, (11), 2011, p143-149Journal Article, 2011, TARA - Full Text
- Flannery, O.M., Britton, J.R., O'Reilly, P., Mahony, N., Prendergast, P.J., Kenny, P.J, The threshold force required for femoral impaction grafting in revision hip surgery: A preliminary study in sow femurs, Acta Orthopaedica, 81, (3), 2010, p303-307Journal Article, 2010, DOI , URL
- Nowlan N.C., Dumas, G., Tajbakhsh S., Prendergast P. And Murphy P. , Passive Movement Due to External Mechanical Stimulation Plays a Role in Embryonic Skeletal Development. , Biomechanics and Modeling in Mechanobiology , epub ahead of print, 2011Journal Article, 2011
- Roddy KA, Prendergast PJ, Murphy P, Mechanical Influences on Morphogenesis of the Knee Joint Revealed through Morphological, Molecular and Computational Analysis of Immobilised Embryos., PloS one, 6, (2), 2011, pe17526Journal Article, 2011, DOI , TARA - Full Text
- P.J. Prendergast, P.E. Galibarov, C. Lowrey, A.B. Lennon, Computer simulating a clinical trial of a load-bearing implant: example of an intramedullary prosthesis, Journal of the Mechanical Behavior of Biomedical Materials, 4, (8), 2011, p1880-1887Journal Article, 2011, DOI , URL , TARA - Full Text
- Nowlan, N.C., Dumas, G., Tajbakhsh, S., Prendergast, P.J., Murphy, P. , Biophysical stimuli induced by passive movements compensate for lack of skeletal muscle during embryonic skeletogenesis , Biomechanics and Modeling in Mechanobiology, 11, (1-2), 2011, p207-219Journal Article, 2011, TARA - Full Text
- Kelly, G.M., Kilpatrick, J.I., van Es, M.H., Weafer, P.P., Prendergast, P.J., Jarvis, S.P. , Bone cell elasticity and morphology changes during the cell cycle , Journal of Biomechanics , 44, (8), 2011, p1484-1490Journal Article, 2011, DOI
- Checa, S. , Prendergast, P.J., Duda, G.N, Inter-species investigation of the mechano-regulation of bone healing: Comparison of secondary bone healing in sheep and rat, Journal of Biomechanics , 44, (7), 2011, p1237-1245Journal Article, 2011, DOI
- Khayyeri, H., Checa, S., Tägil, M., Aspenberg, P., Prendergast, P.J, Variability observed in mechano-regulated in vivo tissue differentiation can be explained by variation in cell mechano-sensitivity, Journal of Biomechanics , 44, (6), 2011, p1051-1058Journal Article, 2011, DOI
- Galibarov, P.E., Prendergast, P.J., Lennon, A.B., A method to reconstruct patient-specific proximal femur surface models from planar pre-operative radiographs, Medical Engineering and Physics, 32, (101), 2010, p1180-1188Journal Article, 2010, DOI
- De Santis, G., Boschetti, F., Lennon, A.B., Prendergast, P.J., Verdonck, P., Verhegghe, B, How an eukaryotic cell senses the substrate stiffness? An exploration using a finite element model with cytoskeleton modelled as tensegrity structure, Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009 , ASME Summer Bioengineering Conference 2009, SBC2009 , Lake Tahoe, CA, 17-21 June, PART A, 2009, pp559-560Conference Paper, 2009
- Boyle, C.J., Lally, C., Prendergast, P.J, Injury driven biological model of restenotic lesion development predicts the effects of stent geometry on restenosis, Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, 11th ASME Summer Bioengineering Conference, SBC2009, Lake Tahoe, edited by 17-21 June , PART B, ASME, 2009, pp1055-1056Conference Paper, 2009
- Nowlan, N.C. , Prendergast, P.J. , Tajbakhsh, S., Murphy, P., Identifying candidate mechanoregulators of skeletal development, Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, 11th ASME Summer Bioengineering Conference, SBC2009, Lake Tahoe, 17-21 June, PART A,, 2009, pp149-150Conference Paper, 2009
- Boyle, C.J., Lennon, A.B., Prendergast P.J., In silico prediction of the mechanobiological response of arterial tissue: application to angioplasty and stenting, Journal of Biomechanical Engineering, 133, (8), 2011, p081001/1 - 081001/10Journal Article, 2011, DOI , TARA - Full Text
- Byrne, D.P., Lacroix, D., Prendergast, P.J., Simulation of fracture healing in the tibia: Mechanoregulation of cell activity using a lattice modeling approach, Journal of Orthopaedic Research, 29, (10), 2011, p1496 - 1503Journal Article, 2011, DOI , URL
- De Santis, G., Lennon, A.B., Boschetti, F., Verhegghe, B., Verdonck, P., Prendergast, P.J., How can cells sense the elasticity of a substrate? An analysis using a cell tensegrity model, European Cells and Materials, 22, 2011, p202 - 213Journal Article, 2011
- Newe, C., Cunningham, E., Buchanan, F., Walker, G., Prendergast, P.J., Lennon, A., Dunne, N., Static and dynamic degradation of sintered calcium phosphate ceramics, Key Engineering Materials, 493-494, 2012, p861 - 865Journal Article, 2012, DOI
- Nowlan, N.C., Dumas, G., Tajbakhsh, S., Prendergast, P.J., Murphy, P., Biophysical stimuli induced by passive movements compensate for lack of skeletal muscle during embryonic skeletogenesis., Biomechanics and Modelling in Mechanobiology, 11, 2012, p207 - 219Journal Article, 2012
- Taylor D, Prendergast PJ, A model for fatigue crack propagation and remodelling in compact bone., Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 211, (5), 1997, p369-75Journal Article, 1997
- McCormack BA, Prendergast PJ, Microdamage accumulation in the cement layer of hip replacements under flexural loading., Journal of biomechanics, 32, (5), 1999, p467-75Journal Article, 1999
- Stolk J, Maher SA, Verdonschot N, Prendergast PJ, Huiskes R, Can finite element models detect clinically inferior cemented hip implants?, Clinical orthopaedics and related research, (409), 2003, p138-50Journal Article, 2003
- McMahon LA, Reid AJ, Campbell VA, Prendergast PJ, Regulatory effects of mechanical strain on the chondrogenic differentiation of MSCs in a collagen-GAG scaffold: experimental and computational analysis., Annals of biomedical engineering, 36, (2), 2008, p185-94Journal Article, 2008
- Andreykiv A, van Keulen F, Prendergast PJ, Computational mechanobiology to study the effect of surface geometry on peri-implant tissue differentiation., Journal of biomechanical engineering, 130, (5), 2008, p051015Journal Article, 2008
- Prendergast PJ, Lally C, Lennon AB, Finite element modelling of medical devices., Medical engineering & physics, 31, (4), 2009, p419Journal Article, 2009
- Checa S, Prendergast PJ, Duda GN, Inter-species investigation of the mechano-regulation of bone healing: comparison of secondary bone healing in sheep and rat., Journal of biomechanics, 44, (7), 2011, p1237-45Journal Article, 2011
- Khayyeri H, Prendergast PJ, The emergence of mechanoregulated endochondral ossification in evolution., Journal of biomechanics, 46, (4), 2013, p731-7Journal Article, 2013
- Boyle CJ, Lennon AB, Prendergast PJ, Application of a mechanobiological simulation technique to stents used clinically., Journal of biomechanics, 46, (5), 2013, p918-24Journal Article, 2013
- Khayyeri H, Isaksson H, Prendergast PJ, Corroboration of computational models for mechanoregulated stem cell differentiation., Computer methods in biomechanics and biomedical engineering, 18, (1), 2015, p15-23Journal Article, 2015, DOI , TARA - Full Text
- Galibarov PE, Prendergast PJ, Lennon AB, A probabilistic modelling scheme for analysis of long-term failure of cemented femoral joint replacements., Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 226, (12), 2012, p927-38Journal Article, 2012
- Biomechanical modelling of cells in mechanoregulation in, editor(s)Gefen, A. , Cellular and Biomolecular Mechanics and Mechanobiology, Berlin, Springer, 2011, pp297 - 329, [Lennon, A.B., Khayyeri, H., Xue, F., Prendergast, P.J.]Book Chapter, 2011
- Rolfe,Rebecca A. , Nowlan,Niamh C. , Kenny,Elaine M. , Cormican,Paul , Morris,Derek W. , Prendergast, Patrick J. ., Kelly, Daniel John ., Murphy, P., Identification of mechanosensitive genes during skeletal development: Alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways, BMC Genomics, 15, (1), 2014, p48-Journal Article, 2014, DOI , URL , TARA - Full Text
- Mechanobiology: Experiment and Computation in, editor(s)PJ Prendergast, PE McHugh , Topics in Bio-Mechanical Engineering, Dublin, Trinity Centre for Bioengineering & National Centre for Biomedical Engineering Science, 2004, pp41 - 57, [Prendergast, PJ]Book Chapter
- Prendergast PJ, McHugh PE (Editors), Topics in Bio-Mechanical Engineering, Dublin, Trinity Centre for Bioengineering & National Centre for Biomedical Engineering Science, 2004, 1 - 249ppBook
- Prendergast, PJ, A non-linear dynamical analysis of the bone-remodelling equations, ASME/AICHE/ASCE Summer Bioengineering Conference, edited by Chandran, KB, Vanderby, R, JR, Hefzy, MS , American Society of Mechanical Engineers, 1997, pp493-4Conference Paper
- Mathematical modelling of microdamage in bone remodelling and adaptation in, editor(s)Odgaard, A, Weinans, H , Bone Structure and Remodelling, Singapore, World Scientific Publishers, 1995, pp213-24 , [Prendergast, PJ, Huiskes, R]Book Chapter
- Tissue adaptation as a discrete-dynamical process in time and space in, editor(s)Pedersen, P, Bendsoe, M , Synthesis in Bio Solid Mechanics, Dordrecht, Kluwer Academic Publishers, 1999, pp321-332 , [Prendergast, PJ, Weinans, H]Book Chapter
- Mechanics of Bone Regeneration in, editor(s)Cowin, SC , Bone Mechanics Handbook, Boca Raton, Crc Press, 2001, pp32.1-32.13 , [Prendergast, PJ, van der Meulen, MCH]Book Chapter
- Prendergast, PJ, McCormack, B, Gunawardhana, T, Taylor, D, The effect of prosthesis orientation on stress shielding using finite element analysis: indications as to bone remodelling, Interfaces in Medicine and Mechanics II, edited by Williams, KR, Toni, A, Middleton, J, Pallotti, G , Elsevier Applied Science, 1991, pp329-339Conference Paper
- Prendergast, PJ, Huiskes, R, The osteon-debonding hypothesis of haversian bone remodelling: osteocytes or bone-lining cells as sensors?, Advances in Bioengineering, edited by Askew, MJ , American Society of Mechanical Engineers, 1994, pp263-4Conference Paper
- Prendergast, PJ, McNamara, BP, Taylor, D, A model to predict bone adaptation based on accumulative damage and repair: finite element simulations, Recent advances in computer methods in Biomechanics and biomedical engineering, edited by Middleton, J, Pande, G, Williams, KR , IBJ Publishers: Swansea, 1993, pp40-49Conference Paper
- Lacroix, D, Prendergast, PJ, Murray, R, McAlinden, S, D'Arcy, E, The use of quantitative computed tomography to generate a finite element model of the scapula bone, Proceedings of the 14th Irish Manufacturing Conference: Sustainable Technology for Manufacturing Industries, Dublin, September 1997, edited by Monaghan, J, Lyons, G , Trinity College Dublin, 1997, pp257-64Conference Paper
- Prendergast, PJ, Murphy, LA, Selection of glenoid prosthesis-type based on an assessment of glenoid bone quality, Proceedings of the 3rd Conference of the International Shoulder Group, edited by Chadwick, EKJ, Veeger, HEJ, van der Helm, FCT, Nagels, J , (ISBN 90-4070-2268-4), DUP Science, 2001, pp83-86Conference Paper
- Bone prostheses and implants in, editor(s)Cowin, SC , Handbook of Bone Mechanics, Boca Raton, CRC Press, 2001, pp35.1-35.39 , [Prendergast, PJ]Book Chapter
- Prendergast, PJ, Biomechanics in Ireland and Europe, Proceedings of the 12th Conference of the European Society of Biomechanics, Dublin, edited by Prendergast, PJ, Lee, TC, Carr, AJ , Royal Academy of Medicine in Ireland, 2000, pp1-4Conference Paper
- Simulation of in-stent restenosis for the design of cardiovascular stents in, G. Holzpafel & R. Ogden , Mechanics of Biological Tissue, Springer, 2006, pp255 - 267, [Lally, C, Prendergast, PJ]Book Chapter
- Experiment and computation in mechanobiology, with new applications in cardiology and evolution in, editor(s)J. Piekarski , Tissue Remodelling, Warsaw, Centre of Excellence for Applied Biomedical Modelling and Diagnostics, 2005, pp219 - 240, [Prendergast, PJ, Nowlan, NC, Lally C]Book Chapter
- Modelling the response of cells to mechanical stimulation in, editor(s)Józef Joachim Telega , Modelling in Biomechanics: Lecture Notes 19 of AMAS (Polish Academy of Sciences), Warsaw, Institute of Fundamental Technological Research, 2005, pp159 - 189, [Prendergast, PJ, Kelly, DJ, McGarry, JG ]Book Chapter
- Prendergast, PJ, Lee, TC, Carr AJ(ed.), 12th Conference of the European Society of Biomechanics, Dublin, 2000, Royal Academy of Medicine in Ireland, 2000, 476 + xvii pProceedings of a Conference
- Prendergast, PJ, Dickson, GR(ed.), The Ulster Biomedical Engineering Society Scientific Meeting, Proceedings of Bioengineering in Ireland, Trinity College, Dublin, 1998, 73 + viii pProceedings of a Conference
- Skeletal structure: synthesis of mechanics and cell biology in, editor(s)JMT Thompson , Visions of the Future: Chemistry and Life Science, Cambridge University Press, 2001, pp113 - 125, [van der Meulen, MCH, Prendergast PJ]Book Chapter
- What a piece of work is a man in, editor(s)EP O'Neill , New Irish Writing in Science, Dublin, Trinity College Dublin, 2003, [Prendergast, PJ]Book Chapter
- Computational mechanobiology in, editor(s)M Cerrolaza, M Doblaré, G Martínez, B Calvo , Computational Bioengineering: Current Trends and Applications, Imperial College Press, 2004, [Prendergast, PJ]Book Chapter
- Analysis of joint and muscle loads in, editor(s)Mow, VC, Huiskes, R , Basic Orthopaedic Biomechanics and Mechanobiology, Lippencodt Williams & Wilkins, 2005, [Prendergast, PJ, van der Helm, FCT, Duda, GN]Book Chapter
- Prendergast, PJ, Biomechanical Techniques for Pre-Clinical Testing of Prostheses and Implants, Warsaw, Institute of Fundamental Technological Research, 2001, 67ppBook
- Prendergast, PJ, Life and Limb: The Bioengineering of Prostheses and Implants (R.I.A. Parsons Medal Lecture), Dublin, Trinity College Dublin, 2003, 30ppBook
- Prendergast, PJ, Taylor, D, A continuum damage approach to bone remodelling, Proceedings of 6th Irish Materials Forum, Advanced Engineered Materials, Dublin, Parsons Press, 1990, pp301-327Conference Paper
- Henn, G, Prendergast, PJ, Taylor, D, An assessment of a particulate composite for use in hip joint prostheses, Proceedings of 6th Irish Materials Forum, Advanced Engineered Materials, Dublin, Parsons Press, 1990, pp283-300Conference Paper
- Prendergast, PJ, Weinans, H, Huiskes, R, Taylor, D, Bone structure and the dynamics of bone adaptation in response to accumulative damage, Proceedings 8th Irish Materials Forum, Key Engineering Materials, 86-87, 1993, pp187-192Conference Paper
- Culleton, TP, Prendergast, PJ, Taylor, D, Problems associated with experimental acelerated fatigue testing of the artificial hip joint, Proceedings 8th Irish Materials Forum, Key Engineering Materials, 86-87, 1993, pp199-205Conference Paper
- Prendergast, PJ, McCormack, BAO, Taylor, D, Innovation initiatives in bioengineering: The Design Forum, Proceedings 11th Irish Manufacturing Conference, Lean Production: From Concept to Product, Belfast, edited by A Storrer , Queen's University of Belfast, 1994, pp319-325Conference Paper
- Prendergast, PJ, Maher, SA, Issues in pre-clinical testing of implants, Proceedings Advances in Materials and PRocessing Technologies 99 & 16th Irish Manufacturing Conference, Dublin, edited by MSJ Hashmi, L Looney , Dublin City University, 1999, pp1195-1202Conference Paper
Research Expertise
His research interests are in biomechanics and implant design, and in tissue engineering and mechanobiology.
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TitleDesign of a bioreactor to induce stem cells to differentiate into specific cell phenotypes to produce cartilage/bone tissueSummaryFunding AgencyEmbark InitiativeDate From2003Date To2006
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TitleBiomechanical interactions in tissue engineering and surgical repair (BITES)SummaryFunding AgencyEuropean CommissionDate From1999Date To2003
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TitleAutomated patient-specific computer simulations of the biomechanical performance of medical implantsSummaryFunding AgencyScience Foundation IrelandDate From2005Date To2008
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TitleThe development of an in-vitro and numerical pre-clinical testing technique to optimise the biomechanical and pharmacological characteristics of intravascular stent designsSummaryFunding AgencyEnterprise IrelandDate From2005Date To2007
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TitleComputer simulation of biodegradation scaffolds: Validation against experiments and implementation for tissue engineeringSummaryFunding AgencyScience Foundation IrelandDate From2009Date To2011
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TitleMechanoresponsiveness of mesenchymal stem cells with ageingSummaryFunding AgencyScience Foundation IrelandDate From2008Date To2010
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TitleMechanoregulation of patterning genes during development of the embryonic skeleton: growth and differentiation in the absence of muscle contractions.SummaryFunding AgencyWellcome TrustDate From2008Date To2010
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TitleSummary
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TitleNovel bioresorbable scaffolds and culture methods for cartilage tissue engineering (SCAFCART)SummaryFunding AgencyEuropean CommissionDate From1999Date To2003
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TitleThe combined role of mechanics and genetics in joint morphogenesis in the developing limb, and identification of mechanosensitive genesSummaryFunding AgencyScience Foundation IrelandDate From2005Date To2008
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TitleA scheme for investigating the evolution of bone remodelling lawsSummaryFunding AgencyEmbark InitiativeDate From2003Date To2006
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TitleHAS Glenoid acromion fixation prosthesesSummaryFunding AgencyStryker-HowmedicaDate From2000Date To2002
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TitleTrinity Centre for Bioengineering and joint programme of research with NUI, GalwaySummaryFunding AgencyHigher Education Authority - PRTLIDate From2002Date To2007
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TitleEvolution and Bone MorphologySummaryFunding AgencyEmbark InitiativeDate From2006Date To2008
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TitlePatient-specific analysis and monitoring of prosthetic implants using computational modellingSummaryFunding AgencyEnterprise IrelandDate From2005Date To2006
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TitleCollaborative Project GrantSummaryFunding AgencyFrench Embassy DublinDate From2007Date To2007
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TitleConstitutive relationships for biomechanical modelling of vascular systemsSummaryFunding AgencyMedtronic/AVE & Enterprise IrelandDate From1999Date To2002
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TitleComputer simulation for improved biofunctionality of implants for middle-ear surgerySummaryFunding AgencyHealth Research BoardDate From1999Date To2002
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TitleAdvanced decision support in medicine: integrating multimedia patient records with computer simulation and protocol based systemsSummaryMediLink: Prof. Jane Grimson, Principal InvestigatorFunding AgencyHigherDate From2000Date To2003
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TitleComputational Mechanobiology: fundamental advances and implementation for medical device engineeringSummaryFunding AgencyScience Foundation IrelandDate From2007Date To2010
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TitlePatient-specific prosthesis analysisSummaryFunding AgencyEnterprise IrelandDate From2002Date To2005
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TitleNEST - Promoting Research on Optimal Methodology and Impacts Supported by ExperienceSummaryFunding AgencyEuropean CommissionDate From2005Date To2007
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TitleTissue engineering of cartilage and bone in a hypoxic environmentSummaryFunding AgencyHealth Research BoardDate From2005Date To2008
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TitleMechanical integrity and architecture of bone relative to osteoporosis, ageing and drug treatment (MIAB)SummaryJointly obtained with Dr. Kevin O'Kelly of Dept. of Mechanical Engineering, TCD.Funding AgencyEuropean CommissionDate From1999Date To2003
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TitleAn International Symposium entitled "Innovation: the third pillar of Irish Higher education?"SummaryFunding AgencyNAIRTLDate From2009Date To2010
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TitleNEST-Promoting Research on Optimal Methodology and Impacts Supported by ExperienceSummaryFunding AgencyCommission of the European CommunitiesDate From15/11/2005Date To14/11/2007
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TitleOptimization of medical implant design: application to ventilation tubes for ottis media with effusionSummaryFunding AgencyEnterprise IrelandDate From2004Date To2005
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TitleSmartCaP - Injectable macroporous biomaterial based on calcium phosphate cement for boneSummaryFunding AgencyEuropean CommissionDate From2004Date To2008
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TitleComputational analysis of the progression of the disease of osteoporosisSummaryFunding AgencyEmbark InitiativeDate From2004Date To2007
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TitleFinite Element Modelling in Biomechanics & Mechanobiology WorkshopSummaryFunding AgencyScience Foundation IrelandDate From2006Date To2007
Recognition
- Fellow, Irish Academy of Engineering 2011
- Honorary Fellow, Oriel College Oxford 2012
- European Society of Biomechanics Research Award (S.M. Perren Award) 1996
- President, Section of Bioengineering, Royal Academy of Medicine in Ireland 1998-00
- Elected Member of the Royal Irish Academy 2008
- Elected to Fellowship of Trinity College Dublin 1998
- Honorary Member, St Peter's College Past Pupils' Union 2023
- Wartenweiler Memorial Lecture, International Society of Biomechanics 2009
- Chief Guest and Speaker at the 28th Convocation Address, Thapar University, Patiala, India 2014
- President Elect of European Alliance of Biomedical Engineering Societies 2006
- President, European Society of Biomechanics 2002-04
- Parsons Medal in Engineering Science, Royal Irish Academy 2003
- Honorary Member, European Society of Biomechanics 2018
- Honorary Fellow, Anatomical Society 2016
- Fellow, Royal Academy of Engineering (International) 2013
- Member of the American Society of Mechanical Engineers -
- Fellow of the Royal Academy of Medicine in Ireland -
- Member of the European Society of Biomechanics -
- Member of the Biomedical Engineering Society (US) -
- Member of the Institution of Engineers of Ireland -
- Member of Tissue Engineering Society International -
- Founding Fellow, European Alliance of Biomedical Engineering Societies (EAMBES)
- Editorial Board of the Journal of the Royal Society, Interface 2004-
- Director, Eblana Photonics, Trinity Enterprise Centre, Pearse St., Dublin, Ireland 2001-
- Guest Editor (with Prof. T.C. Lee) "Micro-damage in Bone", European Journal of Morphology, Vol. 42, Issue Nr. 1/2, 2005 2005
- Chair, European Society of Biomechanics Workshop on Finite Element Modelling in Biomechanics and Mechanobiology 2007
- Editorial Board of the Journal of Orthopaedics and Traumatology 2004-
- Editorial Board of the Journal of Biomechanics (2001-05 as Book Review Editor; 2005- as Surveys Editor) 1999-
- Editorial Board of the Journal of the Royal Society, Interface 2004-
- Editorial Board of the Journal of Biomechanics (2001-05 as Book Review Editor; 2005- as Surveys Editor) 1999-
- President, Section of Bioengineering, Royal Academy of Medicine in Ireland 1998-00
- Guest Editor with Prof. R. Contro, "Mechanics of Tissues and Implants", Meccanica Vol.35, Issue Nr. 4/5, 2002 2002
- President, European Alliance of Medical and Biological Engineering Societies 2007
- Guest Editor with Prof. R. Contro, "Mechanics of Tissues and Implants", Meccanica Vol.35, Issue Nr. 4/5, 2002 2002
- President, European Society of Biomechanics 2002-04
- Chair, European Society of Biomechanics Workshop on Finite Element Modelling in Biomechanics and Mechanobiology 2007
- Director, Eblana Photonics, Trinity Enterprise Centre, Pearse St., Dublin, Ireland 2001-
- President, Section of Bioengineering, Royal Academy of Medicine in Ireland 1998-00
- Guest Editor (with Prof. T.C. Lee) "Micro-damage in Bone", European Journal of Morphology, Vol. 42, Issue Nr. 1/2, 2005 2005
- Editorial Board of the Journal of Orthopaedics and Traumatology 2004-
- Chair, 12th Conference of the European Society of Biomechanics 2000
- President of the European Alliance of Medical and Biological Engineering Societies 2007
- Editorial Board of Clinical Biomechanics 1994-
- Editorial Board of Clinical Biomechanics 1994-
- Chair, 12th Conference of the European Society of Biomechanics 2000
- Examiner, Dottorato di Ricerca (VIII cycle) Scuola Interpolitecnica di Dottorato (Milano, Torino, Bari) 2006-
- External Examiner, Mechanical & Systems Engineering, University of Newcastle 2007
- President, European Society of Biomechanics 2002-04
- Editorial board of European Cells and Materials (www.ecmjournal.org) 2000-
- External Examiner, Mechanical & Systems Engineering, University of Newcastle 2007
- President, European Alliance of Medical and Biological Engineering Societies 2007
- Examiner, Dottorato di Ricerca (VIII cycle) Scuola Interpolitecnica di Dottorato (Milano, Torino, Bari) 2006-
- Editorial board of European Cells and Materials (www.ecmjournal.org) 2000-
- President of the European Alliance of Medical and Biological Engineering Societies 2007