Professor David Hoey

• Brady RT, O'Brien FJ, Hoey DA, Mechanically stimulated bone cells secrete paracrine factors that regulate osteoprogenitor recruitment, proliferation, and differentiation., Biochemical and biophysical research communications, 459, (1), 2015, p118 - 123Journal Article, 2015, TARA - Full Text
• Lee K., Hoey D., Hoey D., Hoey D., Spasic M., Spasic M., Tang T., Tang T., Hammond H., Hammond H., Jacobs C., Adenylyl cyclase 6 mediates loading-induced bone adaptation in vivo, FASEB Journal, 28, (3), 2014, p1157 - 1165Journal Article, 2014, DOI
• Browne L., O'Callaghan S., Hoey D., Griffin P., McGloughlin T., Walsh M., Correlation of Hemodynamic Parameters to Endothelial Cell Proliferation in an End to Side Anastomosis, Cardiovascular Engineering and Technology, 5, (1), 2014, p110 - 118Journal Article, 2014, DOI
• Espinha L., Espinha L., Hoey D., Hoey D., Fernandes P., Rodrigues H., Jacobs C., Oscillatory fluid flow influences primary cilia and microtubule mechanics, Cytoskeleton, 71, (7), 2014, p435 - 445Journal Article, 2014, DOI , TARA - Full Text
• Downs M., Nguyen A., Herzog F., Hoey D., Hoey D., Hoey D., Jacobs C., An experimental and computational analysis of primary cilia deflection under fluid flow, Computer Methods in Biomechanics and Biomedical Engineering, 17, (1), 2014, p2 - 10Journal Article, 2014, DOI
• Hoey D., Hoey D., Hoey D., Chen J., Jacobs C., The primary cilium as a novel extracellular sensor in bone, Frontiers in Endocrinology, 3, (JUN), 2012Journal Article, 2012, DOI
• Hoey D., Hoey D., Hoey D., Tormey S., Ramcharan S., O'Brien F., O'Brien F., Jacobs C., Primary cilia-mediated mechanotransduction in human mesenchymal stem cells, Stem Cells, 30, (11), 2012, p2561-2570Journal Article, 2012, DOI
• Hoey D., Jacobs C., On the horizon from the ORS, Journal of the American Academy of Orthopaedic Surgeons, 19, (1), 2011, p59-62Journal Article, 2011
• Hoey DA, Chen JC, Chua M, Bellon R, Jacobs CR, Mechanical signals promote osteogenic fate through a primary cilia-mediated mechanism., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015Journal Article, 2015, DOI , TARA - Full Text
• Herzog, F.A., Geraedts, J., Hoey, D., Jacobs, C.R., A mathematical approach to study the bending behavior of the primary cilium, Proceedings of the North East Bioengineering Conference, New York, US, 2010Conference Paper, 2010
• Lee, K.L., Hoey, D.A., Jacobs, C.R., Primary cilia-mediated mechanotransduction in bone, Clinical Reviews in Bone and Mineral Metabolism, 8, (4), 2010, p201-212Journal Article, 2010
• Hoey, D.A., Downs, M.E., Jacobs, C.R., The mechanics of the primary cilium: An intricate structure with complex function, Journal of Biomechanics, 45, (1), 2012, p17-26Journal Article, 2012
• Taylor, D., Hoey, D., Sanz, L., O'Reilly, P., Fracture and fatigue of bone and bone cement: The critical distance approach, 2006, pp1025-1026Conference Paper, 2006
• Flanagan AM, Stavenschi E, Basavaraju S, Gaboriau D, Hoey DA, Morrison CG, Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification., Molecular Biology of the Cell, 28, (6), 2017, p736-745Journal Article, 2017
• Labour MN, Riffault M, Christensen ST, Hoey DA, TGFß1 - induced recruitment of human bone mesenchymal stem cells is mediated by the primary cilium in a SMAD3-dependent manner., Nature Scientific Reports, 2016Journal Article, 2016, TARA - Full Text
• O'Connor Mooney R, Davis NF, Hoey D, Hogan L, McGloughlin TM, Walsh MT, On the Automatic Decellularisation of Porcine Aortae: A Repeatability Study Using a Non-Enzymatic Approach., Cells, Tissues, Organs, 2016Journal Article, 2016
• Stavenschi, E., Labour, M.-N., Hoey, D.A., Oscillatory fluid flow induces the osteogenic lineage commitment of mesenchymal stem cells: The effect of shear stress magnitude, frequency, and duration, Journal of Biomechanics, 55, 2017, p99-106Journal Article, 2017
• Electromechanics of bone: Mechanobiological considerations in, editor(s)Tofail, S , Electrically Active Materials for Medical Devices, World Scientific, 2016, pp511-528 , [Coyle, S., Lenehan, B., Hoey, D.A.]Book Chapter, 2016
• The Role of the Primary Cilium in Cellular Mechanotransduction: An Emerging Therapeutic Target in, editor(s)Rawlinson, S. , Mechanobiology: Exploitation for Benefit, Wiley, 2016, pp61-73 , [Eichholz, K.F., Hoey, D.A.]Book Chapter, 2016
• Sankalp Agarwal, Mathieu Riffault, David Hoey, Brendan Duffy, James Curtin, Swarna Jaiswal, Biomimetic Hyaluronic Acid-Lysozyme Composite Coating on AZ31 Mg Alloy with Combined Antibacterial and Osteoinductive Activities, ACS Biomaterials Science & Engineering, 3, (12), 2017, p3244--3253Journal Article, 2017, TARA - Full Text
• Johnson, G.P., English, A.-M., Cronin, S., Hoey, D.A., Meade, K.G., Fair, S., Genomic identification, expression profiling, and functional characterization of CatSper channels in the bovine, Biology of Reproduction, 97, (2), 2017, p302-312Journal Article, 2017, TARA - Full Text
• M. A. Corrigan, T. M. Ferradaes, M. Riffault, D. A. Hoey, Ciliotherapy Treatments to Enhance Biochemically- and Biophysically-Induced Mesenchymal Stem Cell Osteogenesis: A Comparison Study, Cellular and Molecular Bioengineering, 12, (1), 2019, p53--67Journal Article, 2019, TARA - Full Text
• Gillian P. Johnson, Elena Stavenschi, Kian F. Eichholz, Michele A. Corrigan, Sean Fair, David A. Hoey, Mesenchymal stem cell mechanotransduction is cAMP dependent and regulated by adenylyl cyclase 6 and the primary cilium, Journal of Cell Science, 2018, pjcs.222737Journal Article, 2018, TARA - Full Text
• Kelly NP, Flood HD, Hoey DA, Kiely PA, Giri SK, Coffey JC, Walsh MT, Direct mechanical characterization of prostate tissue-a systematic review., The Prostate, 2018Journal Article, 2018, TARA - Full Text
• Agarwal S, Labour MN, Hoey D, Duffy B, Curtin J, Jaiswal S, Enhanced corrosion resistance and cytocompatibility of biomimetic hyaluronic acid functionalised silane coating on AZ31 Mg alloy for orthopaedic applications., Journal of materials science. Materials in medicine, 2018Journal Article, 2018, TARA - Full Text
• Eichholz KF, Hoey DA, Mediating human stem cell behaviour via defined fibrous architectures by melt electrospinning writing., Acta biomaterialia, 2018Journal Article, 2018, DOI , TARA - Full Text
• Michele A. Corrigan, Gillian P. Johnson, Elena Stavenschi, Mathieu Riffault, Marie-Noelle Labour, David A. Hoey, TRPV4-mediates oscillatory fluid shear mechanotransduction in mesenchymal stem cells in part via the primary cilium, Scientific Reports, 8, (1), 2018Journal Article, 2018, TARA - Full Text
• Geoghegan IP, Hoey DA, McNamara LM., Estrogen deficiency impairs integrin "vß3-mediated mechanosensation by osteocytes and alters osteoclastogenic paracrine signalling., Scientific reports, 9, (1), 2019, p4654Journal Article, 2019, DOI , TARA - Full Text
• Brennan CM, Eichholz KF, Hoey DA., The effect of pore size within fibrous scaffolds fabricated using melt electrowriting on human bone marrow stem cell osteogenesis., Biomedical materials (Bristol, England), 14, (6), 2019, p065016Journal Article, 2019, DOI , TARA - Full Text
• Geoghegan IP, Hoey DA, McNamara LM., Integrins in Osteocyte Biology and Mechanotransduction., Current osteoporosis reports, 17, (4), 2019, p195-206Journal Article, 2019, DOI
• Corrigan MA, Coyle S, Eichholz KF, Riffault M, Lenehan B, Hoey DA., Aged Osteoporotic Bone Marrow Stromal Cells Demonstrate Defective Recruitment, Mechanosensitivity, and Matrix Deposition., Cells, tissues, organs, 207, (2), 2019, p83-96Journal Article, 2019, DOI
• Stavenschi E, Hoey DA., Pressure-induced mesenchymal stem cell osteogenesis is dependent on intermediate filament remodeling., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33, (3), 2019, p4178-4187Journal Article, 2019, DOI , TARA - Full Text
• Marie-Noelle Labour, Marina Walsh, Marie Cavaignac, Kian Eichholz, Eamonn deBarra, David A. Hoey, Electrospun Poly-D-L-lactic acid fibrous scaffolds as a delivery vehicle for calcium phosphate salts to promote in situ mineralisation and bone regeneration, Journal of Biomaterials and Tissue Enginering, 8, 2018, p1 - 12Journal Article, 2018, TARA - Full Text
• Eichholz KF, Woods I, Riffault M, Johnson GP, Corrigan M, Lowry MC, Shen N, Labour M, Wynne K, O'Driscoll L, Hoey DA., Human bone marrow stem/stromal cell osteogenesis is regulated via mechanically activated osteocyte-derived extracellular vesicles, Stem Cells Translational Medicine , 2020Journal Article, 2020, DOI , TARA - Full Text
• Parmentier L, Riffault M, Hoey DA., Utilizing Osteocyte Derived Factors to Enhance Cell Viability and Osteogenic Matrix Deposition within IPN Hydrogels., Materials (Basel, Switzerland), 13, (7), 2020Journal Article, 2020, DOI , TARA - Full Text
• Anushree Dwivedi, Patrick A. Kiely, David A. Hoey, Mechanically stimulated osteocytes promote the proliferation and migration of breast cancer cells via a potential CXCL1/2 mechanism, Biochemical and Biophysical Research Communications, 534, 2021, p14--20Journal Article, 2021, TARA - Full Text
• Mathieu Riffault, Gillian P Johnson, Madeline M Owen, Behzad Javaheri, Andrew A Pitsillides, David A Hoey, Loss of Adenylyl Cyclase 6 in Leptin Receptor"Expressing Stromal Cells Attenuates Loading"Induced Endosteal Bone Formation, JBMR Plus, 2020Journal Article, 2020, TARA - Full Text
• Kian F. Eichholz and Stanislas Von Euw and Ross Burdis and Daniel J. Kelly and David A. Hoey, Development of a New Bone"Mimetic Surface Treatment Platform: Nanoneedle Hydroxyapatite (nnHA) Coating, Advanced Healthcare Materials, 2020, p2001102Journal Article, 2020, TARA - Full Text
• Johnson GP, Fair S, Hoey DA, Primary cilium-mediated MSC mechanotransduction is dependent on Gpr161 regulation of hedgehog signalling., Bone, 2021Journal Article, 2021, TARA - Full Text
• Elena Stavenschi, Michele A. Corrigan, Gillian P. Johnson, Mathieu Riffault, David A. Hoey, Physiological cyclic hydrostatic pressure induces osteogenic lineage commitment of human bone marrow stem cells: a systematic study, Stem Cell Research & Therapy, 9, (1), 2018Journal Article, 2018
• Geoghegan IP, McNamara LM, Hoey DA., Estrogen withdrawal alters cytoskeletal and primary ciliary dynamics resulting in increased Hedgehog and osteoclastogenic paracrine signalling in osteocytes., Scientific reports, 11, (1), 2021, p9272Journal Article, 2021, DOI , TARA - Full Text
• Ahern DP, McDonnell JM, Riffault M, Evans S, Wagner SC, Vaccaro AR, Hoey DA, Butler JS., A meta-analysis of the diagnostic accuracy of hounsfield units on computed topography relative to dual-energy X-ray absorptiometry for the diagnosis of osteoporosis in the spine surgery population., The spine journal : official journal of the North American Spine Society, 2021Journal Article, 2021, DOI , TARA - Full Text
• Whelan IT, Moeendarbary E, Hoey DA, Kelly DJ., Biofabrication of vasculature in microphysiological models of bone., Biofabrication, 13, (3), 2021Journal Article, 2021, DOI , TARA - Full Text
• Man K, Brunet MY, Fernandez-Rhodes M, Williams S, Heaney LM, Gethings LA, Federici A, Davies OG, Hoey D, Cox SC., Epigenetic reprogramming enhances the therapeutic efficacy of osteoblast-derived extracellular vesicles to promote human bone marrow stem cell osteogenic differentiation., Journal of extracellular vesicles, 10, (9), 2021, pe12118Journal Article, 2021, DOI
• Andromachi Pouikli, Swati Parekh, Monika Maleszewska, Chrysa Nikopoulou, Maarouf Baghdadi, Ignacio Tripodi, Kat Folz-Donahue, Yvonne Hinze, Andrea Mesaros, David Hoey, Patrick Giavalisco, Robin Dowell, Linda Partridge, Peter Tessarz, Chromatin remodeling due to degradation of citrate carrier impairs osteogenesis of aged mesenchymal stem cells, Nature Aging, 2021Journal Article, 2021, DOI
• Kian F. Eichholz, Angelica Federici, Mathieu Riffault, Ian Woods, Olwyn R. Mahon, Lorraine O"Driscoll, David A. Hoey, Extracellular Vesicle Functionalized Melt Electrowritten Scaffolds for Bone Tissue Engineering, Advanced NanoBiomed Research, 2021, p2100037Journal Article, 2021, DOI
• Nieuwoudt M, Woods I, Eichholz KF, Martins C, McSweeney K, Shen N, Hoey DA., Functionalization of Electrospun Polycaprolactone Scaffolds with Matrix-Binding Osteocyte-Derived Extracellular Vesicles Promotes Osteoblastic Differentiation and Mineralization., Annals of biomedical engineering, 2021, p1 - 15Journal Article, 2021, DOI
• Man K, Brunet MY, Louth S, Robinson TE, Fernandez-Rhodes M, Williams S, Federici AS, Davies OG, Hoey DA, Cox SC., Development of a Bone-Mimetic 3D Printed Ti6Al4V Scaffold to Enhance Osteoblast-Derived Extracellular Vesicles' Therapeutic Efficacy for Bone Regeneration., Frontiers in bioengineering and biotechnology, 9, 2021, p757220Journal Article, 2021, DOI
• 152. Taylor, D., Hoey, D.A., Sanz, L., O'Reilly, P.,, Fracture and fatigue of bone and bone cement: The critical distance approach., Proceedings of European Conference of Fracture, Alexandroupolis , 2006, 2006Conference Paper, 2006
• Hoey, D.A., Taylor, D., , Using the Theory of Critical Distances with FEA to predict Fatigue Failure in Bone Cement, Proceedings of the European Society of Biomechanics, Dublin, Ireland, 2007, 2007Conference Paper, 2007
• Hoey, D.A., , The role of stress concentrations in the fatigue strength of porous PMMA, Proceedings of 10th annual Sir Bernard Crossland Symposium, Galway, Ireland, 2007Conference Paper, 2007
• Hoey, D.A., Taylor, D., , The role of porosity in the fatigue strength of bone cement: the importance of pore size and pore distribution, Proceedings of the Second International Conference on the Mechanics of Biomaterials and Tissues, Hawaii, US, 2007Conference Paper, 2007
• Hoey, D.A., Geraedts, J., Jacobs, C.R., Determining the mechanisms of primary cilia bending in response to fluid shear stress, Society for Physical Regulation in Biology and Medicine Conference, Arizona, US, 2010Conference Paper, 2010
• Herzog, F.A., Geraedts, J., Hoey, D.A., Jacobs, C.R., , A Mathematical Approach to Study the Bending Behavior of the Primary Cilium, North East Bioengineering Conference, New York, US, 2010Conference Paper, 2010
• Downs M., Hoey, D.A., Herzog, F.A., Jacobs, C.R., , Analysis of Primary Cilia Deflection Under Laminar Fluid Flow with 3D Imaging and Advanced Modeling, Biomedical Engineering Society Conference, Austin, US, 2010Conference Paper, 2010
• Kelly, D.J., Hoey, D.A., Jacobs, C.R., , Signals from flow stimulated osteocytes can enhance osteogenic gene expression in mesenchymal stem cells, Orthopaedic Research Society, Long Beach, US, 2011Conference Paper, 2011
• Hoey, D.A., Carette, D., O'Reilly, P., Taylor, D., , The Effect of Stem Geometry in a Porous Bone Cement Mantle, Orthopaedic Research Society, Long Beach, US, 2011Conference Paper, 2011
• Hoey, D.A., Chen, J.C., Ramcharan, S., Shyer, J., Jacobs, C.R., , The effect of Oscillatory Fluid Flow on the Osteogenic Differentiation of Human Bone Marrow Stromal cells, Society for Physical Regulation in Biology and Medicine Conference, Florida, US, 2011Conference Paper, 2011
• Lee, K.L., Hoey, D.A., Tang, T., Hammand, K.H., Jacobs C.R, , TRPV4 is Involved in Mechanotransduction in MC3T3 osteoblasts, 4th New York Skeletal Biology and Medicine Conference, New York, US, 2011Conference Paper, 2011
• Hoey, D.A., Tormey, S., Jacobs, C.R., , A Role for the Primary Cilium in Fluid Flow Mediated Osteogenic Differentiation of Human Mesenchymal Stem Cells, 4th New York Skeletal Biology and Medicine Conference, New York, US, 2011Conference Paper, 2011
• Hoey, D.A., Jacobs, C.R., , Primary Cilia Mediate the Upregulation of COX2 and BMP2 in Response to Oscillatory Fluid Flow in Human Mesenchymal Stem , New York Stem Cell (NYSTEM) Meeting, New York, US, 2011Conference Paper, 2011
• Lee, K.L., Hoey, D.A., Tang, T., Hammand, K.H., Jacobs, C.R., , Adenylyl Cyclase 6 Mediates In Vivo Mechanotransduction In Bone, 4th International Conference on the Mechanics of Biomaterials and Tissues, Hawaii, US, 2011Conference Paper, 2011
• Hoey, D.A., Kelly, D.J., Jacobs, C.R., , Fluid flow stimulation of osteocytes via the primary cilium can enhance osteogenic gene expression in MSCs by a paracrine signaling mechanism, 4th International Conference on the Mechanics of Biomaterials and Tissues, Hawaii, US, 2011Conference Paper, 2011
• Hoey, D.A., O'Brien, F.J., Jacobs, C.R., , The mechanosensing role of the primary cilium in oscillatory fluid flow driven osteogenic differentiation of human bone marrow stromal cells', 4th International Conference on the Mechanics of Biomaterials and Tissues, Hawaii, US, 2011Conference Paper, 2011
• Hoey, D.A., Tormey, S., O'Brien, F.J., Jacobs, C.R., , A Mechanosensory Role for the Primary Cilium in Human Mesenchymal Stem Cells, Orthopedic Research Society, San Francisco, US, 2012Conference Paper, 2012
• Espinha, L., Jacobs, C.R., Hoey, D.A., Oscillatory Fluid Flow Influences the Number of Microtubules Attached to the Base of Primary Cilia, Orthopedic Research Society, San Francisco, US, 2012Conference Paper, 2012
• Lee, K.L., Hoey, D.A., Spasic, M., Tang, T., Hammand, K.H., Jacobs, C.R., , Involvement of Adenylyl Cyclase 6 in Mediating Loading induced Bone Formation. , Society for Physical Regulation in Biology and Medicine Conference, Puerto Rico, 2012Conference Paper, 2012
• Chen, J.C., Hoey, D.A., Jacobs, C.R., The role of Bone Marrow Stem Cells in Loading Induced Osteogenesis, Society for Physical Regulation in Biology and Medicine Conference, Puerto Rico, 2012Conference Paper, 2012
• Hoey, D.A., Tormey, S., O'Brien, F.J., Jacobs, C.R., , Fluid flow sensing via the Primary Cilium in Human Mesenchymal Stem Cells, Exciting Biologies: Forces in Biology, Dublin, Ireland, 2012Conference Paper, 2012
• Lee, K.L., Hoey, D.A., Tang, T., Hammand, K.H., Jacobs, C.R., , Adenylyl Cyclase 6 Mediates Bone Adaptation In Vivo, Orthopedic Research Society, San Francisco, US, 2012Conference Paper, 2012
• Espinha, L., Jacobs, C.R., Hoey, D.A., , Oscillatory Fluid Flow Influences the Number of Microtubules Attached to the Base of Primary Cilia, European Society of Biomechanics, Lisbon, Portugal, 2012Conference Paper, 2012
• Espinha, L., Hoey, D.A., Fernandes, P.R., Rodrigues, H.C., Jacobs, C.R., , OFF influences the Number of Microtubules at the Base of Primary Cilia, 5th National Congress of Biomechanics,, Espinho, Portugal, 2013Conference Paper, 2013
• Chen, J.C., Hoey, D.A., Chua, M.C., Bellon, R.B., Jacobs, C.R., , The Role of Primary Cilia in Bone Marrow Stromal Cells in Mechanically Induced Osteogenesis. , New York Stem Cell (NYSTEM) Meeting, New York, US, 2013Conference Paper, 2013
• Kelly, N., Hoey, D.A., Walsh, M.T., Flood, H., , Mechanical Characterisation of the Prostate: Initial Results, Anatomical Society Meeting, Dublin, Ireland, 2013Conference Paper, 2013
• Chen, J.C., Hoey, D.A., Jacobs, C.R., , Primary Cilia of Bone Marrow Stromal Cells Mediate Mechanically Induced Osteogenesis, American Society of Bone and Mineral Research, Baltimore, US, 2013Conference Paper, 2013
• Chen, J.C., Hoey, D.A., Chua, M., Bellon, R., Jacobs, C.R., , Deletion of Primary Cilia in Bone Marrow Cells Attenuates Mechanically Induced Bone Formation. , Orthopaedic Research Society Meeting, New Orleans, US, 2014Conference Paper, 2014
• Brady, R.T., O'Brien, F.J., Hoey, D.A., , Mechanically Stimulated Osteocytes Direct Stem Cell Proliferation and Recruitment: an in Vitro Study, Orthopaedic Research Society Meeting, New Orleans, US, 2014Conference Paper, 2014
• Brady, R.T., McCoy, R., Hoey, D.A., O'Brien, F.J., , Substrate Stiffness and Fluid Flow Act Synergistically to Direct Osteogenic Differentiation, World Congress of Biomechanics, Boston, US, 2014Conference Paper, 2014
• Hoey, D.A., , Discovering Fundamental Mechanobiological Mechanisms to Develop Bioactive Materials for Regenerative Medicine, European Materials Research Society, Warsaw, Poland, 2014Conference Paper, 2014
• Corrigan, M., Lee, K.L., Labour, M.N., Jacobs, C.R., Hoey, D.A., , Quantification of Fluorescent Calcium Biosensor Signals in Real-time within Discrete Subcellular Compartments of Mesenchymal Stem Cells under physiological loading, Microscopy Ireland, Limerick, Ireland, 2015Conference Paper, 2015
• Labour, M.N., Cavaignac, M., deBarra, E., Hoey, D.A., , Development of a Composite PolyD,L-lactic acid / Calcium Phosphate Electrospun Fibrous Scaffold for Bone Tissue Regeneration, Orthopaedic Research Society, Las Vegas, US, 2015Conference Paper, 2015
• Corrigan, M., Lee, K.L., Labour, M.N., Jacobs, C.R., Hoey, D.A., , Calcium signalling in Response to Fluid Flow within the Primary Cilium Microdomain of Mesenchymal Stem Cells, Orthopaedic Research Society, Las Vegas, US, 2015Conference Paper, 2015
• Stavenschi, E., Labour, M.N., Hoey, D.A., , A Simple In-Vitro Fluid Flow Stimulation Platform To Enhance Osteogenesis Of Human Mesenchymal Stem Cells, Orthopaedic Research Society, Las Vegas, US, 2015Conference Paper, 2015
• Labour, M.N., Hoey, D.A., , TGFβ1 Signalling in Human Mesenchymal Stem Cells is regulated by the Primary Cilium, Orthopaedic Research Society, Las Vegas, US, 2015Conference Paper, 2015
• Brady, R.T., Hoey, D.A., O'Brien, F.J., , Osteocyte Sclerostin Expression Is Directed By Substrate Composition And Dimensionality In Addition To Fluid Flow, Summer Biomechanics, Bioengineering and Biotransport Conference (SB3C2015), , Utah, US, 2015Conference Paper, 2015
• Johnson, G., English. A.M., Hoey, D.A., Meade, K.G., Fair, S., , Comparative Genomic Identification and Expression Profiling of CatSper Genes in the Reproductive Tract of the Bull, The Association for Animal Andrology, France, 2016Conference Paper, 2016
• Johnson, G., Lyons, A., Cronin, S., Hoey, D.A., Fair, S., , CatSper channels regulate bull sperm hyperactivation and rheotaxic response, International Congress on Animal Reproduction, France, 2016Conference Paper, 2016
• Labour, M.N., Coyle, S., Lenehan, B., Christensen, S.T., Hoey, D.A., , TGFβ-1induced chemotaxis in human mesenchymal stem cells requires the primary cilium and is defective in osteoporosis, Orthopaedic Research Society, US, 2016Conference Paper, 2016
• Stavenschi, E., Labour, M.N., Hoey, D.A, The Effect Of Static And Dynamic Pressure On Osteoprogenitor And Osteoblast Gene Expression And Cytoskeleton In Vitro, Orthopaedic Research Society,, US, 2016Conference Paper, 2016
• Geoghegan, I.P., Hoey, D.A., McNamara, L., , The role of integrin αvβ3 in osteocyte mechanotransduction during estrogen deficiency, Matrix Biology Ireland, Galway, Ireland, 2016Conference Paper, 2016
• Labour, M.N., Coyle, S., Lenehan, B., Christensen, S.T., Hoey, D.A., , TGFβ-1induced recruitment of human mesenchymal stem cells is mediated by the primary cilium in a SMAD3-dependent manner, Musculoskeletal Biology & Bioengineering Gordon Research Conference, US, 2016Conference Paper, 2016
• Johnson, G., Corrigan, M., Hoey, D.A., , The role of Adenylyl Cyclase 6 in Mesenchymal Stem Cell Mechanotransduction, Orthopaedic Research Society, US, 2016Conference Paper, 2016
• Stavenschi, E., Labour, M.N., Hoey, D.A., , Oscillatory Fluid Flow Induces MSC Osteogenic Lineage Commitment In A Magnitude And Frequency Dependent Manner. , Orthopaedic Research Society, US, 2017Conference Paper, 2017
• Corrigan, M., Labour, M.N., Riffault, M., Hoey, D.A., , Fluid Shear Induces TRPV4 Mediated Calcium Influx Contributing To Osteogenic Responses In MSCs,, Orthopaedic Research Society, US, 2017Conference Paper, 2017
• Geoghegan, I.P., Hoey, D.A., McNamara, L., , The role of integrin αvβ3 in osteocyte mechanotransduction during estrogen deficiency., Summer Biomechanics, Bioengineering and Biotransport Conference (SB3C2017),, US, 2017Conference Paper, 2017
• Stavenschi, E., Hoey, D.A., , Cyclic hydrostatic pressure mediates early osteogenesis via cytoskeletal remodelling in mesenchymal stem cells. , European Society of Biomechanics, Spain, 2017Conference Paper, 2017
• Eichholz, K., Hoey, D.A., , Melt Electrospun Written Scaffolds as in-vitro platforms for stem cell culture: The effect of scaffold architecture. , TERMIS-EU, Davos, Switzerland, 2017Conference Paper, 2017
• Corrigan, M., Labour, M.N., Riffault, M., Hoey, D.A., , TRPV4-mediates oscillatory fluid shear mechanotransduction in Mesenchymal Stem Cells in part via the primary cilium, Matrix Biology Ireland, Dublin, Ireland, 2017Conference Paper, 2017
• Geoghegan, I.P., Hoey, D.A., McNamara, L., , The role of integrin αvβ3 in osteocyte mechanotransduction during estrogen deficiency, Matrix Biology Ireland, Dublin, Ireland, 2017Conference Paper, 2017
• Riffault, M., Johnson, G., Javaheri, B., Pitsillides, A., Hoey D.A., , Characterisation of Leptin-Receptor as a marker to study skeletal stem cell contributions to bone mechanoadaptation in vivo, Gordon Research Conference, Musculoskeletal Biology and Bioengineering, US, 2018Conference Paper, 2018
• Hoey D.A., , Loading-Induced Bone Formation: A Role for the Skeletal Stem Cell Primary Cilium, European Orthopaedic Research Society, Galway, Ireland, 2018Conference Paper, 2018
• Johnson, G.P., Stavenschi, E., Eichholz, K., Corrigan, M., Hoey D.A., The primary cilium as a potential cAMP responsive mechanosensory in mesenchymal stem cells. , Orthopaedic Research Society, New Orleans, US, 2018Conference Paper, 2018
• Johnson, G.P., Stavenschi, E., Ecihholz, K., Corrigan, M., Hoey D.A., , The primary cilium as a potential cAMP responsive mechanosensory in mesenchymal stem cells. , European Orthopaedic Research Society, Galway, Ireland, 2018Conference Paper, 2018
• Greaney, C., Duffy, C., Hoey D.A., Monaghan, M.G., , Discerning the effect if substrate sirected differentiation on mesenchymal stromal cell metabolic activity using FLIM, European Orthopaedic Research Society, Galway, Ireland, 2018Conference Paper, 2018
• Whelan, I.T., Hoey D.A., Kelly, D.J., , Development of a vascularised bone on a chip , Organ on Chip Meeting, The Netherlands, 2018Conference Paper, 2018
• Dwivedi, A., McCumiskey, M., Hoey, D.A., Kiely, P.A., , Deciphering factors involved in breast cancer etastasis to the one, Irish Association for Cancer Research , Ireland, 2018Conference Paper, 2018
• Eichholz, K., Johnson, G.P., Corrigan, M., Labour, M.N., Wynne, K., Hoey D.A., , Quantitative analysis of the osteocyte secretome following oscillatory fluid shear stimulation , Orthopaedic Research Society, New Orleans, US, 2018Conference Paper, 2018
• Brennan C., Eichholz, K., Hoey, D.A., , Melt Electrospun Written Constructs for Skeletal Tissue Regeneration: The Effect of Pore Size. , Orthopaedic Research Society, New Orleans, US, 2018Conference Paper, 2018
• Riffault, M., Hoey, D.A., , Role of ATP signalling in primary cilium mediated mechanotransduction in human skeletal stem cells., World Congress in Biomechanics, Dublin, Ireland, 2018Conference Paper, 2018
• Woods, I., Shen, N., Eichholz, K., Hoey D.A., , Mechanically activated osteocyte extracellular vesicles promote osteogenic differentiation of human skeletal stem cells, World Congress in Biomechanics, Dublin, Ireland, 2018Conference Paper, 2018
• Corrigan, M., Ferradaes, T., Hoey, D.A., , Can modulating the primary cilium influence bone formation: A comparison of ciliotherapy treatments on stem cell osteogenesis, Orthopaedic Research Society, New Orleans, US, 2018Conference Paper, 2018
• Geoghegan, I.P., Hoey, D.A., McNamara, L., , The role of integrin αvβ3 in osteocyte mechanotransduction during estrogen deficiency, Orthopaedic Research Society, New Orleans, US, 2018Conference Paper, 2018
• Riffault, M., Hoey, D.A., , Role of ATP signalling in primary cilium mediated mechanotransduction in human skeletal stem cells, Orthopaedic Research Society, New Orleans, US, 2018Conference Paper, 2018
• Geoghegan, I.P., Hoey, D.A., McNamara, L., , The role of integrin αvβ3 in osteocyte mechanotransduction during estrogen deficiency, World Congress in Biomechanics, Dublin, Ireland, 2018Conference Paper, 2018
• Johnson, G.P., Stavenschi, E., Eichholz, K., Corrigan, M., Hoey D.A., , The primary cilium as a potential cAMP responsive mechanosensory in mesenchymal stem cells, World Congress in Biomechanics, Dublin, Ireland, 2018Conference Paper, 2018
• Eichholz, K., Hoey D.A., , Melt electrospun written constructs for skeletal tissue regeneration: The effect of fibre architecture on YAP signalling and hMSC differentiation , World Congress in Biomechanics, Dublin, Ireland, 2018Conference Paper, 2018
• Whelan, I.T., Moeendarbary, E., Hoey D.A., Kelly, D.J., , A Microphysiological Model of Vasculature and MSC-derived tissue interaction, Organ on a Chip Meeting, The Netherlands, 2019Conference Paper, 2019
• Khatib, N., Hoey, D.A., Nowlan, N., , Which cell mechanosensors are most critical to normal development of cartilage and ossification in the developing mouse hindlimb , EMBO Workshop - Limb Development: New Tools for a Classic Model System, Barcelona, Spain, 2020Conference Paper, 2020
• Corrigan, M., Labour, M.N., Riffault, M., Hoey, D.A.,, TRPV4-mediates oscillatory fluid shear mechanotransduction in Mesenchymal Stem Cells in part via the primary cilium, World Congress in Biomechanics, Dublin, Ireland, 2018Conference Paper, 2018
• Riffault, M., Johnson, G.P., Owen, M., Javaheri, B., Pitsillides, A., Hoey D.A., , Leptin Receptor expressing stromal cells give rise to a bone lining cell population that mediates loading induced bone formation via adenylyl cyclase 6., Orthopaedic Research Society, Arizona, US. , 2020Conference Paper, 2020
• Eichholz, K., Woods, I., Riffault, M., Johnson, G.P., Shen, N., Corrigan, M., Labour, M.N., Wynne, K., Lowery, M., O'Driscoll, L., Hoey D.A., , Therapeutic delivery of mechanically activated osteocyte-derived extracellular vesicles (MAEVs) for bone regeneration, Orthopaedic Research Society, Arizona, US, 2020Conference Paper, 2020
• Man, K., Brunet, M., Fernandez-Rhodes, M., Williams, S., Davies, O., Federici, A., Hoey D.A., Cox, S.C., , Epigenetic reprogramming enhances the therapeutic efficacy of osteoblast-derived extracellular vesicles for bone regeneration, International Society of Extracellular Vesicles, Virtual, 2021Conference Paper, 2021
• Man, K., Louth, S., Brunet, M., Hoey D.A., Cox, S.C., , The influence of 3D printed scaffold architecture on osteoblast-derived extracellular vesicles therapeutic efficacy for bone repair, International Society of Extracellular Vesicles, Virtual, 2021Conference Paper, 2021
• Brunet, M.Y., Man, K., Williams, S., Davies, O., Hoey D.A., Jones, M-C., Cox, S.C., , Isolation and characterisation of osteoblast-derived extracellular vesicles for the development of bio-inspired osteogenic proteoliposomes., TRAIN-EV International Conference, Dublin, Ireland, 2021Conference Paper, 2021
• Riffault, M., Johnson, G.P., Javaheri, B., Pitsillides, A., Hoey D.A., , Loss of IFT88/primary cilia in leptin receptor expressing stromal cells selectively attenuates loading-induced endosteal bone formation, Orthopaedic Research Society, Virtual, 2021Conference Paper, 2021
• Man, K., Louth, S., Brunet, M., Hoey D.A., Cox, S.C., , The influence of scaffold architecture and composition on osteoblast-derived extracellular vesicles therapeutic efficacy for bone regeneration, 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society, The Netherlands, 2021Conference Paper, 2021
• Whelan, I., Burdis, R., Moeendarbary, E., Hoey, D.A., Kelly, D.J., , Vascularising developing bone organoids on a chip to model endochondral ossification and fracture healing , 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society, The Netherlands, 2021Conference Paper, 2021
• Federici, A., Kelly, D.J., Hoey, D.A., , Development of bio-inspired Melt-Electrowritten scaffolds for vascular regeneration, 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society, The Netherlands, 2021Conference Paper, 2021
• Man, K., Brunet, M., Fernandez-Rhodes, M., Williams, S., Davies, O., Federici, A., Hoey D.A., Cox, S.C., , Epigenetic reprogramming enhances the therapeutic efficacy of osteoblast-derived extracellular vesicles for bone regeneration, 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society, The Netherlands, 2021Conference Paper, 2021
• Luo, L., Foster, N.C., Man, K., Brunet, M., Hoey, D.A., Cox, S.C., Kimber, S.J., El Haj, A.J., Hydrostatic pressure promotes chondrogenic differentiation and microvesicle release from human embryonic and bone marrow stem cells, Biotechnology Journal, 2022, p1-11Journal Article, 2022, URL , TARA - Full Text
• Primary Cilia Mechanobiology in, editor(s)Neibur, G , Mechanobiology, Elsevier, 2019, [Ahern D.A., McFie, M.R., Thompson, C.L., Duffy, M.P., Butler, J.S., Hoey, D.A., ]Book Chapter, 2019
• Cilia Mediated Signalling in, editor(s)Mone Zaidi , Encyclopaedia of Bone Biology, Elsevier, 2019, [Johnson, G.J., Riffault, M., Woods, I., Hoey, D.A., ]Book Chapter, 2019
• Mechanobiology of Primary Cilia in, editor(s)Gefen, A , Cellular and Biomolecular Mechanics and Mechanobiology, 2011, [Kwon, R.Y., Hoey, D.A., Jacobs, C.R., ]Book Chapter, 2011
• Hoey. D.A., Mechano-biologically inspired vesicle-based therapeutics and materials for bone regeneration, WebEVTalk, YouTube, 2021Invited Talk, 2021
• Hoey. D.A., Mechanotherapeutics - Targeting Mechanobiological Cues within the Stem Cell Niche to drive Osteogenesis and Bone Regeneration, School of Pharmacy Seminar Series, Virtual, 2020, School of Pharmacy, University of Dublin, Trinity CollegeInvited Talk, 2020
• Hoey. D.A., Targeting Mechanobiological Cues within the Stem Cell Niche to drive Osteogenesis and Bone Regeneration, Healthcare Technologies Institute Seminar Series, University of Birmingham, Birmingham, UK, 2019, University of Birmingham, Birmingham, UKInvited Talk, 2019
• Hoey, D.A., Targeting Mechanobiological Cues within the Stem Cell Niche to drive Osteogenesis and Bone Regeneration, 16th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, New York, US, 2019, 16th International Symposium on Computer Methods in Biomechanics and Biomedical EngineeringInvited Talk, 2019
• Hoey. D.A., Mechano-biologically inspired vesicle-based therapeutics and materials for bone regeneration, Beacon Mini Symposium, Virtual, 2021, Ireland-Canada University FoundationInvited Talk, 2021
• Hoey. D.A., Melt Electrospun Written Scaffolds with Optimised Fibrous and Mineral Architectures to enhance human MSC Osteogenesis for Bone Regeneration, Tissue Engineering and Regenerative Medicine International Society EU Meeting, Rhodes, Greece, 2019, Tissue Engineering and Regenerative Medicine International SocietyInvited Talk, 2019
• Hoey. D.A., Skeletal Stem Cell Contributions to the Mechanoadaptation of Bone: Direct and Indirect Biophysical Regulation, Gordon Research Conference in Musculoskeletal Biology and Bioengineering, Proctor Academy, US, 2018, Gordon Research ConferenceInvited Talk, 2018
• Hoey, D.A., Stem Cell Contributions to Bone Mechanoadaptation: Direct and Indirect Biophysical Regulation, World Congress in Biomechanics, Dublin, Ireland, 2018, World Congress in BiomechanicsInvited Talk, 2018
• Hoey, D.A., , Stem Cell Contributions to the Mechanoadaptation of Bone, ARI-TCBE-TERG Research Symposium, Dublin, Ireland, 2018, ARI-TCBE-TERG Research SymposiumInvited Talk, 2018
• Hoey, D.A., , Loading-Induced Bone Formation: A Role for the Skeletal Stem Cell Primary Cilium, European Orthopaedic Research Society, Galway, Ireland, 2018, European Orthopaedic Research SocietyInvited Talk, 2018
• Hoey, D.A., Primary Cilium-Mediated Stem Cell Mechanotransduction and Recruitment in Bone, Orthopaedic Research Society Ambassador Symposium, Dublin, Ireland, 2017, Orthopaedic Research Society Ambassador SymposiumInvited Talk, 2017
• Hoey, D.A., Deciphering the molecular mechanisms of stem cell mechanotransduction: A role for the primary cilium, Irish Mechanobiology Network Meeting, Dublin, Ireland, 2016, Irish Mechanobiology NetworkInvited Talk, 2016
• Hoey, D.A., Deciphering the role of the cilium in skeletal stem cell physiology, Membrane Trafficking, Cilia ad Oxygen Sensing, Tokyo, Japan, 2016, Membrane Trafficking, Cilia ad Oxygen Sensing CommitteeInvited Talk, 2016
• Hoey, D.A., Impact of the ERC on my Research and Career, Royal Irish Academy (ERC President Visit), Royal Irish Academy, Dublin, Ireland, 2014, Royal Irish AcademyInvited Talk, 2014
• Hoey, D.A., Discovering Fundamental Mechanobiological Mechanisms to Develop Bioactive Materials for Regenerative Medicine, European Materials Research Society (Fall Meeting), Warsaw, 2014, European Materials Research SocietyInvited Talk, 2014
• Hoey, D.A., Research Strategy: Standing Out From the Crowd, University of Limerick Lunchtime Research Seminars, Limerick, Ireland, 2014, University of LimerickInvited Talk, 2014
• Hoey, D.A., Primary Cilium-Mediated Mesenchymal Stem Cell Mechanobiology in Bone, Queens University Belfast ERC Workshop, Queens University Belfast, 2015, Queens University BelfastInvited Talk, 2015
• Hoey, D.A., Primary Cilia Mechanobiology: from Molecule to Mouse, Irish Cilia Biology Network, Dublin, Ireland, 2014, Irish Cilia Biology NetworkInvited Talk, 2014
• Hoey, D.A., My Career in Biomaterials: A case study of challenges that led to opportunities, European Society of Biomaterials Meeting, Young Scientist Workshop "Career Development - Challenges and Opportunities", , Madrid, Spain, 2013, European Society of BiomaterialsInvited Talk, 2013
• Hoey, D.A., , Stem Cell Contributions to Loading-Induced Bone Formation: A Role of the Primary Cilium, CLASS Conway Institute Seminar Series, UCD, Dublin, Ireland, 2013, CLASS Conway Institute, University College DublinInvited Talk, 2013
• Hoey, D.A., Bone Mechanobiology - A Role for Mechanics in Treatment Development, University Hospital Limerick Grand Rounds, Limerick, Ireland, 2013, University Hospital LimerickInvited Talk, 2013
• Hoey, D.A., My ERC Application: Perspectives and Insights, University of Limerick EU grant Proposals - Maximizing your Success Workshop, Limerick, Ireland, 2013, University of LimerickInvited Talk, 2013
• Hoey, D.A., Primary Cilium-mediated Stem Cell Mechanobiology in Bone, Hospital for Special Surgery Seminar Series, New York, US, 2013, Hospital for Special SurgeryInvited Talk, 2013
• Hoey, D.A., Primary Cilium-Mediated Mechanobiology in Bone, Queen Mary, University of London Seminar Series, 2013, Queen Mary, University of LondonInvited Talk, 2013
• Hoey, D.A., A Role for the Primary Cilium in Bone Mechanobiology, Biomechanics Seminar Series at the National University of Ireland, National University of Ireland, Galway, Ireland, 2012Invited Talk, 2012
• Hoey, D.A., Biomaterials and Mechanobiology: Studies in Bone, Materials Ireland Symposium, University of Limerick, 2012, Materials IrelandInvited Talk, 2012
• Hoey, D.A., The Broad Spectrum of Bioengineering: Biomaterials to Mechanobiology, Materials and Surface Science Institute Research Forum, University of Limerick, Ireland, 2012, Materials and Surface Science InstituteInvited Talk, 2012
• Hoey, D.A., Stress Concentrations in Bone Cement: A Critical Distance Approach, Biomedical Engineering Graduate Seminar Series, Columbia University in the City of New York, New York, US, 2010, Columbia University in the City of New YorkInvited Talk, 2010
• Hoey, D.A,, The Primary Cilium: Fact Not Fiction, The Royal College of Surgeons in Ireland, TERG Seminar Series, The Royal College of Surgeons in Ireland, Dublin, Ireland, 2011, The Royal College of Surgeons in IrelandInvited Talk, 2011
• Brady, R.T., O'Brien, F.J., Hoey, D.A., The Impact of the Extracellular Matrix Environment on Sost Expression by the MLO-Y4 Osteocyte Cell Line, Bioengineering, 9, (1), 2022, p1-35Journal Article, 2022, DOI
• Man, K., Barroso, I.A., Brunet, M., Peacock, B., Federici, A.S., Hoey, D.A., Cox, S.C., Controlled Release of Epigenetically-Enhanced Extracellular Vesicles from a GelMA/Nanoclay Composite Hydrogel to Promote Bone Repair, International Journal of Molecular Sciences, 23, (2), 2022, p1-22Journal Article, 2022, DOI
• Sankalp Agarwal, Muhammad Morshed, Marie-Noelle Labour, David Hoey, Brendan Duffy, James Curtin, Swarna Jaiswal, Enhanced corrosion protection and biocompatibility of a PLGA-silane coating on AZ31 Mg alloy for orthopaedic applications, RSC advances, 6, (115), 2016, p113871-113883Journal Article, 2016, DOI
• M. Sarmast. Sh., S.George., A.B. Dayang Radiah., D.A. Hoey., N. Abdullah., S. Kamarudin, Synthesis of bioactive glass using cellulose nano fibre template, Journal of the Mechanical Behavior of Biomedical Materials, 130, (105174), 2022Journal Article, 2022
• Man K, Brunet MY, Federici AS, Hoey DA, Cox SC., An ECM-Mimetic Hydrogel to Promote the Therapeutic Efficacy of Osteoblast-Derived Extracellular Vesicles for Bone Regeneration., Frontiers in bioengineering and biotechnology, 10, 2022, p829969Journal Article, 2022, DOI
• Eichholz K.F., Goncalves I., Barcelo X., Federici A.S., Hoey D.A., Kelly D.J., How to design, develop and build a fully-integrated melt electrowriting 3D printer, Additive Manufacturing, 58, 2022Journal Article, 2022, DOI , TARA - Full Text
• Villapun Puzas, V.M. and Carter, L.N. and Schroder, C. and Colavita, P.E. and Hoey, D.A. and Webber, M.A. and Addison, O. and Shepherd, D.E.T. and Attallah, M.M. and Grover, L.M. and Cox, S.C., Surface Free Energy Dominates the Biological Interactions of Postprocessed Additively Manufactured Ti-6Al-4V, ACS Biomaterials Science and Engineering, 2022Journal Article, 2022, DOI , TARA - Full Text
• Eichholz, K.F. and Freeman, F.E. and Pitacco, P. and Nulty, J. and Ahern, D. and Burdis, R. and Browe, D.C. and Garcia, O. and Hoey, D.A. and Kelly, D.J., Scaffold microarchitecture regulates angiogenesis and the regeneration of large bone defects, Biofabrication, 14, (4), 2022Journal Article, 2022, DOI , URL
• Ahern, D., Moran, B., Butler, J.S., Hoey D.A., , A Comparative analysis of the Human Skeletal Stem Cell and Mesenchymal Stromal Cell in Bone Tissue Regenerative Medicine , Orthopaedic Research Society, Dallas, U.S., 10/02/2023-14/02/202, 2023Conference Paper, 2023
• Petrousek, S., Cobban, M., Kelly, D.J., Hoey D.A., , Targeting mechanosignalling to modulate the immune environment for bone repair , Orthopaedic Research Society, Dallas, U.S., 10/02/2023-14/10/202, 2023Conference Paper, 2023
• Cobban, M., Martin, C., Maggio, M., Hoey D.A., , The Role of GPR-161 in Osteocyte Mechanosignalling and Osteoclastogenic Paracrine Signaling , Orthopaedic Research Society, Dallas, US, 10-14/02/2023, 2023Conference Paper, 2023
• Kruger, E., Buscher, J., Hoey D.A., Taylor, D., O"Reilly, P., Crowley, Q., , Skeletal structure alteration of cold-water coral Lophelia pertusa from ocean acidification and rising seawater temperature , International Coral Reef Symposium, Bremen, Germany, 2022, 2022Conference Paper, 2022
• Villapun Puzas, V.M., Carter, L.N., Schröder, C., Colavita, P.E., Hoey, D.A., Webber, M.A., Addison, O., Shepherd, D.E.T., Attallah, M.M., Grover, L.M., Cox, S.C., , Surface Free Energy Dominates the Biological Interactions of Postprocessed Additively Manufactured Ti-6Al-4V, European Society of Biomaterials, Bordeaux, France, 2022, 2022Conference Paper, 2022
• Shen, N., Woods, I., Lowery, M., Eichholz, K.F., Stavenschi, E., Martins, C.S., Maggio, M., O"Driscoll, L., Hoey D.A., , Mature bone cells drive vessel formation via an extracellular vesicle mediated mechanism following mechanical stimulation , Orthopaedic Research Society, Dallas, US, 2023, 2023Conference Paper, 2023
• Hoey D.A., , Mechanically activated bone derived extracellular vesicles as a multitargeted therapeutic for tissue repair. , Gordon Research Conference, Musculoskeletal Biology and Bioengineering, US, 2022, 2022Conference Paper, 2022
• Man, K., Barroso, I., Brunet, M., Peacock, B., Federici, A., Hoey D.A., Cox, S.C.,, Controlled release of epigenetically-activated extracellular vesicles from a gelMA/nanoclay composite hydrogel to promote bone repair, International Society of Extracellular Vesicles, Lyon, France, 2022, 2022Conference Paper, 2022
• Khatib, N.S., Ahmed, S., Huang, Y., Hoey D.A., Nowlan, N.C., , Mechano-regulatory role of TRPV4 in prenatal limb development, Orthopaedic Research Society, Florida, US, 2022Conference Paper, 2022
• The Pros and Cons of Fatigue Loading of Bone in, editor(s)Hoey, D., and Kennedy, O., , 1. Perspectives on the Mechanics of Fracture and Biological Materials., LuLu Publishing, 2022, pp55-65 , [Hoey, D.A., ]Book Chapter, 2022
• Hoey, D., and Kennedy, O., Perspectives on the Mechanics of Fracture and Biological Materials, LuLu Publishing, 2022Book, 2022, TARA - Full Text
• Hoey. D.A., , Harnessing mechanics to better inform strategies for tissue regeneration, Matrix Biology Ireland Conference, Limerick, Ireland, 2022, 2022Invited Talk, 2022
• Hoey. D.A.,, The Pros and Cons of Fatigue Loading of Bone, Perspectives on the Mechanics of Fracture and Biological Materials, A Festschrift in Honour of David Taylor, Dublin, Ireland, 2022, 2022Invited Talk, 2022
• Hoey. D.A., Mechano-biologically inspired therapeutics and materials for bone repair, Orthopaedic Research Society Meeting, Dallas, U.S., 2023, 2023Invited Talk, 2023
• Hoey. D.A., Mechano-biologically inspired therapeutics and materials for bone regeneration, Tissue and Cell Engineering Society Conference, Birmigham, U.K., 2022, 2022Invited Talk, 2022
• Hoey. D.A., , Targeting mechanosignalling to modulate bone repair, eCM meeting on Bone and Fracture Repair, Davos, Switzerland, 2023, 2023Invited Talk, 2023
• Federici, A., Garcia, O., Kelly, D.J., Hoey, D.A.,, Development of a bio-inspired off-the-shelf small diameter vascular graft, Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society, Manchester, UK, 2023Conference Paper, 2023
• Martins, C.S., Maggio, M., Tsiapalis, D., O"Driscoll, L., Hoey D.A.,, Mature bone cells drive vessel formation via an extracellular vesicle mediated mechanism following mechanical stimulation, European Chapter of the Tissue Engineering and Regenerative Medicine International Society, Manchester, UK, 2023Conference Paper, 2023
• Maggio, M., Martins, C.S., Petrousek, S., Hoey, D.A.,, Bone cell regulation of osteoclastogenesis is dependent on the stage of lineage commitment and mechanical environment, Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society, Manchester, UK, 2023Conference Paper, 2023
• Petrousek, S., Kelly, D.J., Hoey, D.A.,, Targeting mechanosignaling to modulate the immune environment for bone repair, Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society, Manchester, UK, 2023Conference Paper, 2023
• Cobban, M., Martin, C., Maggio, M., Hoey D.A.,, The Role of GPR-161 in Osteocyte Mechanosignalling and Osteoclastogenic Paracrine Signaling, Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society, Manchester, UK, 2023Conference Paper, 2023
• Krueger ET, Büscher JV, Hoey DA Taylor D, O'Reilly PJ, Crowley QG, Wanted Dead or Alive: Skeletal Structure Alteration of Cold-Water Coral Desmophyllum pertusum (Lophelia pertusa) from Anthropogenic Stressors, Oceans, 4, (1), 2023, p68 - 79Journal Article, 2023, DOI , TARA - Full Text
• Nidal S Khatib, James Monsen, Saima Ahmed, Yuming Huang, David A Hoey, Niamh C Nowlan, Mechanoregulatory role of TRPV4 in prenatal skeletal development, SCIENCE ADVANCES, 9, (4), 2023Journal Article, 2023, DOI , URL , TARA - Full Text
• Whelan IT, Burdis R, Shahreza S, Moeendarbary E, Hoey DA, Kelly DJ., A microphysiological model of bone development and regeneration., Biofabrication, 2023Journal Article, 2023, DOI
• Man K, Eisenstein NM, Hoey DA, Cox SC., Bioengineering extracellular vesicles: smart nanomaterials for bone regeneration., Journal of nanobiotechnology, 21, (1), 2023, p137Journal Article, 2023, DOI
• Neto, N.G.B., Suku, M., Hoey, D.A, Monaghan, M.G, 2P-FLIM unveils time-dependent metabolic shifts during osteogenic differentiation with a key role of lactate to fuel osteogenesis via glutaminolysis identified, Stem Cell Res Ther, 14, (364), 2023Journal Article, 2023, DOI
• Angelica S Federici, Brooke Tornifoglio, Caitríona Lally, Orquidea Garcia, Daniel J Kelly, David A Hoey, Melt electrowritten scaffold architectures to mimic tissue mechanics and guide neo-tissue orientation, Journal of the Mechanical Behavior of Biomedical Materials, 150, 2024, p1 - 15Journal Article, 2024, DOI , TARA - Full Text
• Shen N, Maggio M, Woods I, C Lowry M, Almasri R, Gorgun C, Eichholz KF, Stavenschi E, Hokamp K, Roche FM, O'Driscoll L, Hoey DA., Mechanically activated mesenchymal-derived bone cells drive vessel formation via an extracellular vesicle mediated mechanism., Journal of tissue engineering, 14, 2023, p20417314231186918Journal Article, 2023, DOI
• Maryam Sarmast Shoushtari, David Hoey, Dayang Radiah Awang Biak, Norhafizah Abdullah, Suryani Kamarudin, Halimatun S. Zainuddin, Sol"gel"templated bioactive glass scaffold: a review, Research in Biomedical Engineering, 40, 2024, p281 - 296Journal Article, 2024, DOI , TARA - Full Text
• Maryam Sarmast Shoushtari, Aina Shafiqah Wan Mahmood, Dayang Radiah Awang Biak, Samaneh Alijantabar Aghouzi, David Hoey, Suryani Kamarudin, Norhafizah Abdullah, Halimatun Sakdiah Zainuddin, Effect of Starch Binders on the Properties of Bioglass Tablets for Bone Tissue Engineering Applications, Starch, 2024Journal Article, 2024, DOI
• Bríd Murphy, Carolina Martins, Mimma Maggio, Mick A. Morris, David A. Hoey, Nano sized gallium oxide surface features for enhanced antimicrobial and osteo-integrative responses, Colloids and Surfaces B: Biointerfaces, 227, 2023, p113378Journal Article, 2023, DOI
• Hoey, D.A., Jacobs, C.R., Oscillatory fluid flow affects the osteogenic differentiation of human bone marrow stromal cells in a primary cilium dependent manner, ASME 2011 Summer Bioengineering Conference, SBC 2011, (PARTS A AND B), 2011, p331-332Journal Article, 2011, DOI
• Sarmast Sh, M., Dayang Radiah, A.B., Hoey, D.A., Abdullah, N., Zainuddin, H.S., Kamarudin, S, The structural, mechanical, and biological variation of silica bioglasses obtained by different sintering temperatures., Journal of Sol-Gel Science and Technology, 2024Journal Article, 2024, DOI , TARA - Full Text
• Federici, A., Garcia, O., Kelly, D.J., Hoey D.A.,, Muticomponent Melt-Electrowritten Vascular Graft to Mimic and Guide Regeneration of Small Diameter Blood Vessels, Advanced Functional Materials, 2409883, 2024Journal Article, 2024, DOI , URL , TARA - Full Text
• Shoushtari, M.S. and Hoey, D. and Biak, D.R.A. and Abdullah, N. and Kamarudin, S. and Zainuddin, H.S., Solâ€"gelâ€'templated bioactive glass scaffold: a review, Research on Biomedical Engineering, 40, (1), 2024, p281-296Journal Article, 2024, DOI , URL
• Sarmast Sh, M. and Leow, Y.S. and Dayang Radiah, A.B. and Abdullah, N. and Alijantabar Aghouzi, S. and Hoey, D. and Kamarudin, S. and Zainuddin, H.S., Evaluation of bioactivity and antibacterial properties of bioglass fabricated using a cellulose nano fibre template, Materials Chemistry and Physics, 304, (127863), 2023Journal Article, 2023, DOI , URL
• Labour, M.-N. and Riffault, M. and Christensen, SÞ.T. and Hoey, D.A., TGFβ1-induced recruitment of human bone mesenchymal stem cells is mediated by the primary cilium in a SMAD3-dependent manner, Scientific Reports, 6, (35542), 2016Journal Article, 2016, DOI , URL
• Labour, M. and Christensen, S. and Hoey, D., TGFβ1 Signalling in human mesenchymal stem cells is regulated by the primary cilium, Cilia, (SUPPLEMENT 1), 2015Journal Article, 2015, DOI , URL
• Hoey D and Taylor D , Fatigue in porous PMMA: the effect of stress concentrations, International Journal of Fatigue, 30, 2008, p989 - 995Journal Article, 2008
• Taylor D and Hoey D, High cycle fatigue of welded joints: the TCD experience, International Journal of Fatigue, 31, 2009, p20 - 27Journal Article, 2009, DOI
• Hoey D and Taylor D, Quantitative analysis of the effect of porosity on the fatigue strength of bone cement., Acta Biomaterialia, 5, 2009, p719 - 726Journal Article, 2009, DOI
• Hoey D and Taylor D, Comparison of the fatigue behaviour of two different forms of PMMA, Fatigue and Fracture of Engineering Materials and Structures, 32, 2009, p261 - 269Journal Article, 2009, DOI
• Hoey D and Taylor D, Statistical distribution of the fatigue strength of porous bone cement. , Biomaterials, 30, 2009, p6309 - 6317Journal Article, 2009, DOI
• Hoey D and Taylor D, The effect of mixing technique on fatigue of bone cement when stress concentrations are present., International Journal of Nano and Biomaterials, 3, 2010, p36 - 48Journal Article, 2010, DOI
• Hoey, D.A., Kelly, D.J., Jacobs, C.R., A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells. , Biochemical and Biophysical Research Communications, 412, (1), 2011, p182-187Journal Article, 2011, DOI , URL , TARA - Full Text
• , The role of stress concentrations in the bone cement mantle, edited by df , (PART A), 2009, pp463-464Conference Paper, 2009
• (ed.), Fatigue in PMMA: The effect of notches and pores predicted using the TCD, 2, 2008, 1570-1575 pProceedings of a Conference, 2008

• Hoey, D.A., O'Reilly, P, Taylor, D., , Fatigue behaviour of PMMA vs PMMA based bone cement, Proceedings of the 14th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Sligo, 2008Conference Paper
• Hoey, D.A., Jacobs, C.R., , Human Mesenchymal Stem Cells Utilize the Primary Cilium as a Mechanosensor during Oscillatory Fluid Flow Driven Osteogenic Differentiation, Columbia University Stem Cell Day, New York, US, 2011Conference Paper
• Brady, R.T., Hoey, D.A., O'Brien, F.J., , Mechanically Stimulated Osteocytes Secrete Soluble Factors Which Alter Mesenchymal Stem Cell Proliferation and Migration, 18th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Belfast, Ireland, 2012Conference Paper
• Brady, R.T., O'Brien, F.J., Hoey, D.A., , Mechanically Stimulated Osteocyte Conditioned Media Alters Mesenchymal Stem Cell Proliferation and Migration, Royal College of Surgeons in Ireland Research Day, 2012Conference Paper
• Brady, R.T., McCoy, R., Hoey, D.A., O'Brien, F.J., , The Combined Effect of Substrate Stiffness and Fluid Flow in Directing Osteogenic Differentiation, 19th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Enfield, Ireland, 2013Conference Paper
• Brady, R.T., McCoy, R., Hoey, D.A., O'Brien, F.J., Elucidation Of The Role Of Biophysical Environment In Directing Differentiation Of Stems Cells, Royal College of Surgeons in Ireland Research Day, Dublin, Ireland, 2013Conference Paper
• Kelly, N., Hoey, D.A., Walsh, M.T., Flood, H., , Prostate tissue stiffness can be correlated to severity of symptoms in Benign Prostatic Hyperplasia, University Hospital Limerick Annual Research Symposium, Limerick, Ireland, 2013Conference Paper
• Brady, R.T., O'Brien, F.J., Hoey, D.A., , Novel mechanisms in loading-induced bone formation, University Hospital Limerick Annual Research Symposium, Limerick, Ireland, 2013Conference Paper
• Eichholz, K.F., Hoey, D.A., , Fabrication of in-vitro micro-vessels for the study of cardiovascular mechanobiology, University Hospital Limerick Annual Research Symposium, Limerick, Ireland, 2013Conference Paper
• Hoey, D.A., , Primary Cilium-Mediated Stem Cell Mechanobiology in Bone, University Hospital Limerick Annual Research Symposium, Limerick, Ireland, 2013Conference Paper
• Brady, R.T., O'Brien, F.J., Hoey, D.A., , Mechanically Stimulated Osteocytes and Osteoblasts Direct Stem Cell Migration and Proliferation: an in vitro Study, 20th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Limerick, Ireland, 2014Conference Paper
• Eichholz, K.F., Hoey, D.A., , Fabrication of in-vitro micro-vessels for the study of cardiovascular mechanobiology, 20th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Limerick, Ireland, 2014Conference Paper
• Kelly, N., Mulvihill, J., Giri, S., Hoey, D.A., Flood, H., Walsh, M.T., , Voiding symptom severity is related to prostate tissue stiffness in Benign Prostatic Hyperplasia, 20th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Limerick, Ireland, 2014Conference Paper
• Stavenschi, E., Hoey, D.A., , Design of a 2D bioreactor for fluid flow stimulation of mesenchymal stem cells: parallel plate flow chamber, 20th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Limerick, Ireland, 2014Conference Paper
• Hoey, D.A., Chen, J.C., Jacobs, C.R., , Primary Cilia of Bone Marrow Cells Mediate Mechanically Induced Bone Formation, 20th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Limerick, Ireland, 2014Conference Paper
• Corrigan, M., Lee, K.L., Jacobs, C.R., Hoey, D.A., , Characterisation of calcium signaling within the primary cilium of stem cells using FRET biosensor technology, University Hospital Limerick Annual Research Symposium, Limerick, Ireland, 2014Conference Paper
• Stavenschi, E., Hoey, D.A, A simple in-vitro fluid flow stimulation platform to enhance osteogenesis of human mesenchymal stem cells, University Hospital Limerick Annual Research Symposium, Limerick, Ireland, 2014Conference Paper
• Labour, M.N., Hoey, D.A., , TGFβ-1 induced Stem Cell Migration in Bone is Associated with the Primary Cilium, University Hospital Limerick Annual Research Symposium, Limerick, Ireland, 2014Conference Paper
• Meaney, C., Kiely, P., Hoey, D.A., , Investigating the Incidence and Role of Primary Cilia in Cancer Models, University Hospital Limerick Annual Research Symposium, Limerick, Ireland, 2014Conference Paper
• Eichholz, K.F., Hoey, D.A., , Optimising Scaffold Morphology via the Controlled Deposition of Melt Electrospinning Fibers, University Hospital Limerick Annual Research Symposium, Limerick, Ireland, 2014Conference Paper
• Labour, M.N., Cavaignac, M., deBarra, E., Hoey, D.A., , Development of a composite poly-lactic acid / calcium phosphate electrospun material for bone tissue engineering, University Hospital Limerick Annual Research Symposium, Limerick, Ireland, 2014Conference Paper
• Labour, M.N., Cavaignac, M., deBarra, E., Hoey, D.A., , The development of a Self-mineralizing PolyD,L-lactic acid/Calcium Phosphate electrospun scaffold for bone tissue regeneration , 21st Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Dublin, 2015Conference Paper
• Labour, M.N., Christensen, S.T., Hoey, D.A., , Regulation of TGFβ1 Signalling by the Primary Cilium in Mesenchymal Stem Cells, 21st Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Dublin, Ireland, 2015Conference Paper
• Kelly, N., Mulvihill, J., Hoey, D.A., Giri, S., Flood, H., Walsh, M.T., , Mechanical, histological and biochemical analysis of benign hyperplastic prostate tissue, 21st Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Dublin, Ireland, 2015Conference Paper
• Stavenschi, E., Labour, M.N., Hoey, D.A., , Enhanced Osteogenic Differentiation Of Human Mesenchymal Stem Cells Using A Simple In-Vitro Fluid Flow Bioreactor , 21st Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Dublin, Ireland, 2015Conference Paper
• Coyle, S., Corrigan, M., Hoey, D.A., , Isolation and characterisation of Mesenchymal Stem Cells from osteoporotic/osteoarthritic patients. , 21st Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Dublin, Ireland, 2015Conference Paper
• Johnson, G., Hoey, D.A., , Investigate the expression, localization and role of Adenylyl Cyclase 6 in mesenchymal stem cell osteogenic differentiation, 21st Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Dublin, Ireland, 2015Conference Paper
• Eichholz, K.F., Hoey, D.A., , Design of a 3-axis Direct Writing Apparatus for Controlled Deposition of Melt Electrospun Fibres., 21st Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Dublin, Ireland, 2015Conference Paper
• Corrigan, M., Lee, K.L., Labour, M.N., Jacobs, C.R., Hoey, D.A., , Fluid Flow-Induced Bending of the Primary Cilium Triggers a Distinct Intraciliary Calcium Flux in Mesenchymal Stem Cells, 21st Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Dublin, Ireland, 2015Conference Paper
• Stavenschi, E., Hoey, D.A., , The Effect Of Static And Dynamic Pressure On Early Osteogenesis in Osteoprogenitors And Osteoblasts In Vitro, 22nd Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Galway, Ireland, 2016Conference Paper
• Corrigan, M., Johnson, G.P., Stavenschi, E., Hoey, D.A., , TRPV4 is required for flow mediated calcium signalling and osteogenic lineage commitment Mesenchymal Stem Cells. , 22nd Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Galway, Ireland, 2016Conference Paper
• Eichholz, K., Hoey, D.A., , Design and Fabrication of Tissue Engineering Scaffolds using Melt Electrospinning Writing, 22nd Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Galway, Ireland, 2016Conference Paper
• Labour, M.N., Coyle, S., Lenehan, B., Christensen, S.T., Hoey, D.A., , TGFβ-1induced chemotaxis in human mesenchymal stem cells requires the primary cilium and is defective in osteoporosis, 22nd Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Galway, Ireland, 2016Conference Paper
• Johnson, G., Corrigan, M., Hoey, D.A., , The role of Adenylyl Cyclase 6 in Mesenchymal Stem Cell Mechanotransduction, 22nd Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Galway, Ireland, 2016Conference Paper
• Eichholz, K., MacGuinness, A., Hoey, D.A., , Design and Fabrication of Tissue Engineering Scaffolds using Melt Electrospinning Writing., Orthopaedic Research Society, US, 2016Conference Paper
• Stavenschi E., Hoey, D.A., , Cyclic Hydrostatic Pressure Enhances Osteogenic Gene Expression and Alters the Cytoskeletal Network of Mesenchymal Stem Cells. , 23rd Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2017Conference Paper
• Johnson, G., Corrigan, M., Stavenschi, E., Hoey, D.A., , Primary Cilia mediated MSC mechanotransduction is dependent on adenylyl cyclase 6 and cyclic AMP signalling, 23rd Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2017Conference Paper
• McKee, B., Corrigan, M., Hoey, D.A., , Are Mesenchymal Stem Cells more mechano-sensitive in low oxygen environments such as exists within bone marrow, 23rd Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2017Conference Paper
• Riffault, M., Hoey, D.A., , Role of ATP signalling in Fluid Flow-induced osteogenic commitment of mesenchymal stem cells, 23rd Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2017Conference Paper
• Corrigan, M., Riffault, M., Johnson, G., Hoey, D.A., , Targeting of TRPV4 mimics the mechanotransduction response to fluid shear in Mesenchymal Stem Cells. , 23rd Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2017Conference Paper
• Brennan, C., Eichholz, K., Hoey, D.A., , The effect of pore size melt electrospun written PCL scaffolds on mesenchymal stem cell osteogenic differentiation, 23rd Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2017Conference Paper
• Geoghegan, I.P., Hoey, D.A., McNamara, L., , The role of integrin αvβ3 in osteocyte mechanotransduction during estrogen deficiency., 23rd Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2017Conference Paper
• Eichholz, K., Hoey, D.A., , Melt Electrospun Written Scaffolds as in-vitro platforms for stem cell culture: The effect of scaffold architecture on MSC osteogenesis. , 23rd Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland,, 2017Conference Paper
• Geoghegan, I.P., Hoey, D.A., McNamara, L., , The role of integrin αvβ3 in osteocyte mechanotransduction during estrogen deficiency, UL-NUIG Research Day, Galway, 2017Conference Paper
• Riffault, M., Hoey, D.A., , Role of ATP signalling in primary cilium mediated mechanotransduction in human skeletal stem cells. , 24th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2018Conference Paper
• Stavenschi, E., Hoey, D.A., , Cyclic hydrostatic pressure remodels the intermediate filament network and enhances osteogenic gene expression in mesenchymal stem cells, 24th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2018Conference Paper
• Eichholz, K., Hoey, D.A., , Melt Electrospun Written Constructs for Skeletal Tissue Regeneration: The Effect of Fibre Architecture., 24th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2018Conference Paper
• Johnson, G., Corrigan, M., Stavenschi, E., Hoey, D.A., The , The primary cilium as a pontential cAMP responsive mechanosensory in mesenchymal stem cells, 24th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2018Conference Paper
• Corrigan, M., Ferradaes, T., Hoey, D.A., , Can modulating the primary cilium influence bone formation: A comparison of ciliotherapy treatments on stem cell osteogenesis, 24th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2018Conference Paper
• Shen, N., Woods, I., Hoey D.A., , Mechanically activated osteoclast and osteocyte derived paracrine factors induce angiogenesis stimulation , 24th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2018Conference Paper
• Woods, I., Shen, N., Eichholz, K., Hoey D.A., , Mechanically stimulated osteocytes coordinate stem cell recruitment via extracellular vesicle cell-cell communication, 24th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2018Conference Paper
• Whelan, I.T., Hoey D.A., Kelly, D.J., , Development of a vascularised bone on a chip , 24th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2018Conference Paper
• Geoghegan, I.P., Hoey, D.A., McNamara, L., , The role of integrin αvβ3 in osteocyte mechanotransduction during estrogen deficiency. , 24th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2018Conference Paper
• Dwivedi, A., McCumiskey, M., Hoey, D.A., Kiely, P.A., , Deciphering factors involved in breast cancer metastasis to the one, European Association of Cancer Research, Ireland, 2018Conference Paper
• Eichholz, K., Woods, I., Shen, N., Johnson, G.P., Corrigan, M., Labour, M.N., Wynne, K., Lowery, M., O'Driscoll, L., Hoey D.A., , Quantitative analysis of the osteocyte secretome following oscillatory fluid shear stimulation., European Orthopaedic Research Society, Galway, Ireland, 2018Conference Paper
• Geoghegan, I.P., Hoey, D.A., McNamara, L., , The role of integrin αvβ3 in osteocyte mechanotransduction during estrogen deficiency, European Orthopaedic Research Society, Galway, Ireland, 2018Conference Paper
• Stavenschi, E., Hoey, D.A., , Cyclic hydrostatic pressure remodels the intermediate filament network and enhances osteogenic gene expression in mesenchymal stem cells, Orthopaedic Research Society, New Orleans, US, 2018Conference Paper
• Stavenschi, E., Hoey, D.A., , Cyclic hydrostatic pressure induces human SSC lineage commitment in a magnitude dependent manner. , Orthopaedic Research Society, New Orleans, US, 2018Conference Paper
• Johnson, G., Corrigan, M., Stavenschi, E., Hoey, D.A., , MSC contributions to loading induced bone formation: a role for Adenylyl Cyclase 6. , 25th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2019Conference Paper
• Eichholz, K., Woods, I., Johnson, G.P., Mahon, O.R., Federici, A., Corrigan, M., Lowery, M., O'Driscoll, L., Hoey D.A., , Mimicking cellular and ECM mechanobiological cues to drive MSC osteogenesis and bone regeneration, 25th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2019Conference Paper
• Parmentier, L., Hoey D.A., , Upscaling the production of mechanically activated secreted factors and optimising their local delivery via material functionalisation, 25th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2019Conference Paper
• Federici, A., Eichholz, K., Kelly, D.J., Hoey, D.A., Development of melt electrospun written tubular scaffolds for vascular tissue engineering applications , 25th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2019Conference Paper
• Riffault, M., Johnson, G.P., Owen, M., Javaheri, B., Pitsillides, A., Hoey D.A., , Leptin Receptor expressing stromal cells give rise to a bone lining cell population that mediates loading induced bone formation via adenylyl cyclase 6. , 26th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2020Conference Paper
• Whelan, I., Moeendarbary, E., Hoey, D.A., Kelly, D.J., , A microphysiological model of human bone tissue , 26th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2020Conference Paper
• Geoghegan, I.P., Hoey, D.A., McNamara, L., , The role of integrin αvβ3 in osteocyte mechanotransduction during estrogen deficiency, 25th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2019Conference Paper
• Federici, A., Eichholz, K., Cunniffe, G.M., Kelly, D.J., Hoey, D.A., , Development of bio-inspired scaffolds for vascular tissue engineering applications, 26th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Ireland, 2020Conference Paper
• Maggio, M., Hoey, D.A., , Identification of mechanically regulated miRNAs in osteocytes and secreted extracellular vesicles, 27th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Galway, Ireland, 2022, 2022Conference Paper
• Martins, C., Hoey, D.A., , Mechanical stimulation of osteocytes enhances the regenerative capacity of the secretome, 27th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Galway, Ireland, 2022, 2022Conference Paper
• Petrousek, S., Kelly, D.J., Hoey D.A., , Identification of mechanotherapeutics to modulate the immune environment for bone repai, 27th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Galway, Ireland, 2022, 2022Conference Paper
• Federici, A., Kelly, D.J., Hoey, D.A., , Development of a bio-inspired scaffold for small diameter vascular regeneration , 27th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Galway, Ireland, 2022, 2022Conference Paper
• Cobban, M., Martins, C., Kelly, D.J., Hoey D.A., , The role of GPR161 in osteocyte physiology and mechanobiology , 27th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Galway, Ireland, 2022Conference Paper
• Federici, A., Garcia, O., Kelly, D.J., Hoey, D.A.,, Development of a bio-inspired off-the-shelf small diameter vascular graft, 28th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Enfield, 2023Conference Paper
• Martins, C.S., Maggio, M., Tsiapalis, D., O"Driscoll, L., Hoey D.A.,, Mature bone cells drive vessel formation via an extracellular vesicle mediated mechanism following mechanical stimulation, 28th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Enfield, Ireland, 2023Conference Paper
• Maggio, M., Martins, C.S., Petrousek, S., Hoey, D.A., , Bone cell regulation of osteoclastogenesis is dependent on the stage of lineage commitment and mechanical environment , 28th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Enfield, Ireland, 2023Conference Paper
• Petrousek, S., Kelly, D.J., Hoey, D.A.,, Targeting mechanosignaling to modulate the immune environment for bone repair, 28th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Enfield, Ireland, 2023Conference Paper
• Cobban, M., Martin, C., Maggio, M., Hoey D.A.,, The Role of GPR-161 in Osteocyte Mechanosignalling and Osteoclastogenic Paracrine Signaling, 28th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Enfield, Ireland, 2023Conference Paper
• Hoey D, Taylor D and O'Reilly P, Predicting fatigue failure in bone cement, Bioengineering in Ireland 12, Galway, January 2006, edited by P.McHugh , Royal Academy of Medicine in Ireland, 2006, pp43-Conference Paper
• Hoey D, Taylor D and O'Reilly P, The role of defects in the fatigue strength of bone cement, Bioengineering in Ireland 13, Enniskillen, Northern Ireland, January 2007, edited by Orr J , RAMI, 2007, pp53-Conference Paper

The focus of my lab (www.hoeylab.com) is to delineate the importance of mechanics in human physiology and utilise this fundamental information to inform the development of novel strategies for tissue regeneration. Core Research areas: " Biomechanics, Mechanobiology, and Mechanotransduction " Primary Cilium and Ciliotherapies " Extracellular Vesicles and Related Therapies " Organ-on-Chip, Biofabrication, Melt Electrowriting I have secured considerable competitive research funding in the form of multiple European Research Council grants (Starting-2013&PoC-2018) and a Science Foundation Ireland (SFI) Frontier"s grant (2020). This facilitated a transformational research program where I am uncovering the role of mechanics and particularly the role of the primary cilium in bone mechanoadaptation. This very successful program has led to a series of high impact papers (Stem Cells-JIF:6.94, Nature Aging-projectedJIF:40) and established me as a world leader in cilia mechanobiology, best reflected by the numerous invited keynotes/awards at leading global conferences (Eg: Gordon conference/Orthopaedic Research Society (sect.6.5)). This funding has also formed the basis of a new research program on extracellular vesicles (SFI-Frontiers-2020). Utilising mechanics to prime the regenerative properties of vesicles, I am discovering novel mechanisms by which exercise promotes health, that I am harnessing therapeutically. I have published extensively in the leading journals in this area (J.EV-JIF:21.2) and delivered multiple international keynote talks (Eg: eCM2022 (sect.6.5)). I am also an Investigator in the world-leading SFI-AMBER centre. I have collaborative funding with the multinational company Johnson&Johnson, stemming from exciting technological advancements I"ve made in Melt-Electrowriting. Through fundamental discovery (ActaBiomaterilia-JIF:10.6) and commercial exploitation (4xIDFs) I have established myself as pioneer in this area as demonstrated by keynote talk at TERMIS-EU. My research has defined important transformational research questions that has established me as an international leader in my field.

• Title

  How to Promote Spinal Fusion in Osteoporosis: A Bioprinting Strategy
  Summary

  Spinal fusion is a surgical procedure whereby two or more vertebrae are joined together to grow into a single solid bone. Indications for fusion procedures include fractured vertebrae, tumour resection and degenerative spinal conditions. The incidence of spinal fusion surgery is rising dramatically worldwide, in part due to an ever increasing aging population. In the setting of osteoporosis, which is also linked to aging, spinal fusion is associated with significant technical challenges, morbidity and healthcare costs. More than 200 million people are suffering from osteoporosis worldwide. Insufficiency fractures, failure of fusion and instrumentation failure are some of the complications encountered. Furthermore, the revision surgery required to address these complications is a major surgical undertaking associated with significant risk and long-term functional restrictions. Our hypothesis is that the increased incidence of complications is secondary to a defective stem cell population, and this may be therapeutically addressed through the use of novel bioprinted materials. We will first track the stem cell contributions to spinal fusion using a transgenic mouse model and compare how this is altered in an induced osteoporotic model (Workpackage 1). In workpackage 2 we will characterise stem cells isolated from osteoporotic and non-osteoporotic patients undergoing spinal fusion surgery. We will compare the regenerative potential of these cells to patient spinal fusion outcomes with the hypothesis that those patients with poor fusion outcomes will correlate with the quality of stem cells. Finally, we will attempt to use novel bioprinted materials previously optimised to enhance stem cell based bone formation to increase spinal fusion rates in the mouse model described earlier. Therefore this project will identify stem cells as critical to spinal fusion success and will demonstrate the applicability of novel materials to target this cell to enhance fusion in osteoporosis addressing the currently unacceptable high failure rates of this procedure.
  Funding Agency

  Irish Research Council
  Date From

  01/09/2019
  Date To

  31/08/2022
• Title

  Microphysiological models of human bone: A new platform for investigation and drug screening.
  Summary

  This project will combine expertise within the applicant's team, along with collaborators in the University of Birmingham, to develop new materials and cell culture platforms which will facilitate the recapitulation of human bone physiology in a dish, focusing on the establishment of a human osteocyte network within a vascularised and mineralised tissue that is capable of undergoing remodelling, in response to both hormonal and physical cues. This first of its kind platform will then be used to screen novel therapeutics which are being developed by the applicant in the form of extracellular vesicles (EVs) and G-protein coupled receptors (Gpr161) as treatments for osteoporosis and will compare against commercial standards.
  Funding Agency

  Trinity College Dublin
  Date From

  01/01/2020
  Date To

  31/12/2023
• Title

  Osteoprogenitor Regulation in Loading-induced Bone Formation: An Alternative Approach to Treating Osteoporosis
  Summary

  Every 30 seconds a person suffers an osteoporosis-related bone fracture, resulting in significant morbidity, mortality, and health-care costs estimated at 36billion euro annually. Current therapeutics target osteoclasts but are associated with severe side effects. Osteoporosis arises when stem cells (MSCs) fail to produce sufficient numbers of osteoblasts. A key regulator of MSC behaviour is loading, yet the mechanisms by which MSCs proliferate, differentiate and are recruited to sites of loading to replace exhausted osteoblasts remain elusive. Osteocytes are ideally numbered and positioned to be sensors and regulators of bone formation. However research on osteocyte-MSC signalling is almost non-existent. Therefore the objective of this research project is to determine the role of the osteocyte and associated signalling mechanisms in regulating MSC contributions to bone formation and to develop novel 'Bone-on-a-Chip' microfluidic platforms for the validation of novel anabolic therapeutics for osteoporosis.
  Funding Agency

  Irish Research Council
  Date From

  2014
  Date To

  2018
• Title

  Primary Cilium Mediated Mesenchymal Stem Cell Mechanobiology in Bone
  Summary

  Every 30 seconds a person suffers an osteoporosis-related bone fracture in the EU, resulting in significant morbidity, mortality, and health-care costs estimated at €36 billion annually. Current therapeutics target bone resorbing osteoclasts, but these are associated with severe side effects. Osteoporosis arises when mesenchymal stem cells (MSC) fail to produce sufficient numbers of bone forming osteoblasts. A key regulator of MSC behaviour is physical loading, yet the mechanisms by which MSCs sense and respond to changes in their mechanical environment are virtually unknown. Primary cilia are nearly ubiquitous 'antennae-like' cellular organelles that have very recently emerged as extracellular mechano/chemo-sensors and thus, are strong candidates to play an important role in regulating MSC responses in bone. However, to date, research on the stem cell primary cilium is almost non-existent. Therefore, the objective of this research program is to determine the role of the understudied primary cilium and associated molecular components in the osteogenic differentiation and recruitment of human MSCs in loading-induced bone adaptation. This will be achieved through ground breaking in vitro and in vivo techniques developed by the applicant. The knowledge generated in this proposal will represent a profound advance in our understanding of stem cell mechanobiology. In particular, the identification of the cilium and associated molecules as central to stem cell behaviour will lead to the direct manipulation of MSCs via novel cilia-targeted therapeutics that mimic the regenerative influence of loading at a molecular level. These novel therapeutics would therefore target bone formation rather than resorption, providing an innovative alternative path to treatment, resulting in an improved supply of bone forming cells, preventing osteoporosis. Furthermore, these novel therapeutics will be incorporated into biomaterials generating novel bioactive osteoinductive scaffolds. These advances will not only improve quality of life for the patient but will significantly reduce the financial burden of bone loss diseases in the EU.
  Funding Agency

  European Research Council
  Date From

  01/11/2013
  Date To

  31/10/2018
• Title

  Mechanically Activated Extracellular Vesicles as a Multi-targeted Therapy to Enhance Bone Regeneration
  Summary

  Every 3 seconds a person suffers an osteoporosis-related bone fracture, resulting in significant morbidity, mortality, and health-care costs. Osteoporosis arises when there is an imbalance between resorption and formation resulting in net bone loss. Current therapeutics are limited in efficacy and by side-effects. A potent regulator of bone formation and repair is physical loading. Bone cells sense mechanical stimuli and subsequently coordinate net bone gain by secreting multitargeted paracrine factors. Recent findings by the applicant indicates that these factors are delivered via extracellular vesicles (EV), which are membrane-bound cargoes that facilitate cell-cell communication. Therefore, this research aims to develop a novel EV-based multitargeted therapy that mimics the beneficial effects of physical exercise, by inhibiting osteoclastogenesis and bone resorption, while also enhancing angiogenesis, osteogenesis and bone formation. The identification of EVs and associated components as central to loading-induced bone anabolism will lead to the direct manipulation of multiple cell types via mechanically-activated EV based therapeutics. These therapeutics would therefore be used as a novel multitargeted strategy to treat osteoporosis. Furthermore, these EVs will be incorporated into scaffolds, generating innovative mechanobiomimetic materials for bone regeneration. These therapies have the potential to transform how millions suffering from osteoporosis and bone defects are treated.
  Funding Agency

  Science Foundation Ireland
  Date From

  01/01/2020
  Date To

  31/12/2023

Other engineering and technologies, Basic Medicine and Life Sciences, Condensed matter physics, Medical and biomedical engineering, Biochemistry and cell biology,

• 'Short talk travel award' at the Society for Physical Regulation in Biology and Medicine, Florida, U.S. 2011
• University of Limerick Award for Research Excellence (Early Career) 2014
• Senior author on paper awarded 1st prize in the `Mechanobiology" section at the Bioengineering in Ireland Conference, Enfield, Ireland. Awarded to Ms. Mimma Maggio, 2023. 2023
• Co-author on paper awarded 'Lab on a Chip Poster Prize' at Organ on a Chip and Tissue on a Chip Conference, Rotterdam, The Netherlands. Awarded to Mr. Ian Whelan 2018
• Senior author on paper shortlisted for the 'New Investigator Recognition Award' at the 61st Orthopaedic Research Council Meeting, Las Vegas, U.S. 2015
• Co-author on paper awarded 3rd prize in the poster competition at the 2016 UL/NUIG Research Day. Awarded to Ms. Gillian Johnson. 2016
• Co-author on paper awarded the 'Harold M. Frost Young Investigator Award' at the 43rd International Bone and Mineral Society Sun Valley Workshop, Idaho, U.S. 2013
• Senior author on paper awarded the `Engineers Ireland Biomedical Research Medal" from the Society of Engineers Ireland. Awarded to Mr. Stephane Petrousek, 2024. 2024
• Senior author on thesis awarded 'Best Undergraduate Final Year Project' awarded to Mr. Kian Eichholz at the Materials and Surface Science Institute Research Day, University of limerick, Limerick, Ireland. 2014
• Fellow of Trinity College Dublin (FTCD) 2021
• Senior author on poster awarded 1st prize in the `Orthopaedics" section at the Trinity Centre for Biomedical Engineering Research Day, Dublin, Ireland. Awarded to Ms. Mimma Maggio, 2022. 2022
• Senior author on paper awarded 1st prize in the `Mechanobiology' section (Early Career) at the Bioengineering in Ireland Conference, Galway, Ireland. Awarded to Ms. Morgan Cobban, 2022. 2022
• Senior author on paper awarded 2nd prize in the `Mechanobiology' section at the Bioengineering in Ireland Conference, Dublin, Ireland. Awarded to Stephane Petrousek, 2022. 2022
• Co-author on paper awarded the New Investigator Recognition Award at the Orthopaedic Research Society Meeting, Florida, US. 2022 2022
• Senior author on paper awarded 'Best poster in the Technology and Health Section' of the Inaugural University Hospital Limerick Research Symposium, Limerick, Ireland. 2013
• 'Outstanding Junior Investigator' at the 4th New York Skeletal Biology and Medicine Meeting, New York, U.S. 2011
• Finalist for the 'New Investigator Recognition Award' at the Orthopaedic Research Society, San Francisco, US. 2012
• Marie Sk"odowska"Curie Curie COFUND Excellence award, Luxembourg. 2015
• 'Best presentation in the Postdoctoral Category' at the Society for Physical Regulation in Biology and Medicine, Arizona, U.S. 2010
• 2nd prize in the poster competition at the 4th Mechanics of Biomaterials and Tissues Meeting, Hawaii, U.S. 2011
• Senior author on paper awarded 1st prize in the 'Biomechanics' section at the Bioengineering in Ireland Conference, Dublin, Ireland. Awarded to Dr. Mathieu Riffault 2020
• 1st prize at the Sir Bernard Crossland Symposium, National University of Ireland: Galway. 2007
• 'Symington Bequest Fund Award' from the Anatomical Society, U.K. 2012
• Co-author on paper awarded the 'ASBMR Young Investigator Award' at the American Society for Bone and Mineral Research, Baltimore, U.S. 2013
• 'Engineers Ireland Biomedical Research Medal' from the Society of Engineers Ireland. 2008
• Senior author on talk awarded 1st prize in the `Orthopaedics" section at the Trinity Centre for Biomedical Engineering Research Day, Dublin, Ireland. Awarded to Mr. Stephane Petrousek, 2022. 2022
• Senior author on paper awarded 1st prize in the `Mechanobiology" section at the Bioengineering in Ireland Conference, Newcastle, Ireland. Awarded to Ms. Morgan Cobban, 2024. 2024
• Senior author on paper awarded the 'Engineers Ireland Biomedical Research Medal' from the Society of Engineers Ireland. Awarded to Mr. Kian Eichholz 2019
• Senior author on paper awarded 1st prize at the Sir Bernard Crossland Symposium, Queens University Belfast, Northern Ireland. Awarded to Mr. Kian Eichholz. 2016
• Senior author on paper awarded 2nd prize at the Thesis in 3 Trinity Centre for Bioengineering competition, Dublin, Ireland. Awarded to Mr. Kian Eichholz. 2016
• Senior author of paper awarded 1st prize at the Sir Bernard Crossland Symposium, Ireland. Awarded to Mr. Kian Eichholz. 2016 2016
• Senior author on paper awarded 'Best poster in the Technology and Health Section' at the 2nd University Hospital Limerick Research Symposium, Limerick, Ireland. 2014
• Co-author on paper awarded the 'New Investigator Recognition Award' at the 60th Orthopaedic Research Council Meeting, New Orleans, U.S. 2014
• Co-author on paper awarded 1st prize in the student poster competition at the 2018 Health Research Institute Conference, University of Limerick, Ireland. Awarded to Ms. Anushree Dwivedi. 2018
• Senior author on poster awarded 3rd prize at the Trinity Centre for Biomedical Engineering Research Day, Dublin, Ireland. Awarded to Mr. Rosario Milazzo, 2023. 2023
• Senior author on paper awarded 1st prize in the `Regenerative Medicine' section (Early Career) at the Bioengineering in Ireland Conference, Galway, Ireland. Awarded to Ms. Mimma Maggio, 2022. 2022
• 1st prize in the PhD poster competition at the American Society of Mechanical Engineers Bioengineering Division Summer Conference, Florida, U.S. 2008
• 'Best presentation in the Postdoctoral Category' at the Society for Physical Regulation in Biology and Medicine, Florida, U.S. 2011
• Senior author on paper awarded 2nd prize in the student competition at the 2017 Bioengineering in Ireland Conference, Belfast, Northern Ireland. Awarded to Ms. Michele Corrigan. 2017

• Engineers Ireland (Committee member and Treasurer of the Biomedical Division 2012-2016) 2006
• Anatomical Society 2009
• European Society of Biomechanics (ESB) Present
• Orthopaedic Research Society (ORS) Present
• Tissue Engineering and Regenerative Medicine Society (TERMIS) Present
• Marie-Curie Fellow Association Present

• Annual Reviewer for Orthopaedic Research Society Meeting: Topic: Biomaterials Topic: Bone 2016 - Present
• Engineers Ireland- Biomedical Engineering Committee member. " Committee member (2012-2018). Provided academic expertise to the secretariat with relevance to the Biomedical Sector. Organised a programme of events, such as evening lectures, to strengthen the learned body function and support the CPD requirements of members, and social events to facilitate networking. " Assistant secretary (2014-2015). Organized events throughout the year to promote Biomedical Engineering to members. This included visits to large multinational companies in the MedTech area. 2015-2018
• Reviewer for 46 leading journals in the fields of Mechanobiology, Biomechanics, and Biomaterials incl..: Nature Nanotechnology, Nature Materials, Nature Scientific Reports, Science Advances, Advanced Materials, Advanced Functional Materials, Advanced Healthcare Materials, Acta Biomaterilia, ACS Applied Materials and Interfaces, ACS Biomaterials Science and Engineering, Aging Cell, Annals of Biomedical Engineering, Bioactive Materials, BIOCELL, Biofabrication, Biomechanics and Modelling in Mechanobiology, Biomedical Engineering Online, Bioresearch Open Access, Bone, Bone and Joint Research, Cell and Molecular Bioengineering, Cell and Molecular Life Sciences, Cellular Signaling, Cytoskeleton, DNA and Cell Biology, eCells and Materials, FASEB Journal, Frontiers in Medicine, International Journal of Clinical Rheumatology, International Journal of Nanomedicine, Journal of Anatomy, Journal of Applied Bioscience, Journal of Biomechanics 2011-Present
• Reviewer for 9 leading funding agencies internationally: European Research Council Advanced Panel, France National Research Agency, Cancer Research UK, Dr. Hadwen Trust for Humane Research UK, Biotechnology and Biological Sciences Research Council UK, Einstein Foundation Germany, NOW Veni Gran Program New Zealand, Netherlands Organization for Scientific Research, University of Wisconsin Institute for Clinical and Translational Research KL2 Program US. 2013 - Present
• External Academic Program Examiner- Cork IT Biomedical Engineering Programs (Level 7 and Level 8) 2016 - 2019
• Editorial Board Member: Nature: Scientific Reports 2019 - 2022
• External PhD Examiner " Dr. Mylène de Ruijter, Utrecht University (2020) " Dr. Michael Collins, University of Limerick (2019) " Dr. Kristin Lee, Columbia University in the City of New York (2014) Doctoral Committee Member " Ms. Yuan Mu, Kings College London 2014 - Present