Dr. Juan Labrador
Associate Professor, Genetics

Asadzadeh J, Neligan N, Kramer SG, Labrador JP, Tinman Regulates NetrinB in the Cardioblasts of the Drosophila Dorsal Vessel., PloS one, 11, (2), 2016, pe0148526 Journal Article, 2016 URL DOI TARA - Full Text

Asadzadeh J, Neligan N, Canabal-Alvear JJ, Daly AC, Kramer SG, Labrador JP, The Unc-5 Receptor Is Directly Regulated by Tinman in the Developing Drosophila Dorsal Vessel., PloS one, 10, (9), 2015, pe0137688 Journal Article, 2015 TARA - Full Text DOI URL

Molecular Coevolution: Methods and Applications in, editor(s)Mario A Fares , Natural Selection: Methods and Applications, CRC Press, 2014, pp211 - 237, [Fares M.A., Labrador JP] Book Chapter, 2014 URL Other DOI

Zarin AA, Asadzadeh J, Hokamp K, McCartney D, Yang L, Bashaw GJ, Labrador JP, A transcription factor network coordinates attraction, repulsion, and adhesion combinatorially to control motor axon pathway selection., Neuron, 81, (6), 2014, p1297-311 Journal Article, 2014 TARA - Full Text DOI

Santiago C, Labrador JP, Bashaw GJ, The homeodomain transcription factor Hb9 controls axon guidance in Drosophila through the regulation of Robo receptors., Cell Reports, 7, (1), 2014, p153-65 Journal Article, 2014 TARA - Full Text DOI

Zarin AA, Asadzadeh J, Labrador JP, Transcriptional regulation of guidance at the midline and in motor circuits., Cellular and molecular life sciences : CMLS, 71, (3), 2013, p419-32 Journal Article, 2013 DOI

Zarin, A.A., Daly, A.C., Hülsmeier, J., Asadzadeh, J., Labrador, J.-P., A GATA/homeodomain transcriptional code regulates axon guidance through the Unc-5 receptor, Development , 139, (10), 2012, p1798-1805 Journal Article, 2012 TARA - Full Text DOI

Fares MA, Ruiz-González MX, Labrador JP, Protein coadaptation and the design of novel approaches to identify protein-protein interactions., IUBMB life, 63, (4), 2011, p264-71 Journal Article, 2011 DOI TARA - Full Text URL

Coleman HA, Labrador JP, Chance RK, Bashaw GJ., The Adam family metalloprotease Kuzbanian regulates the cleavage of the roundabout receptor to control axon repulsion at the midline., Development., 137, (14), 2010, p2417-2426 Journal Article, 2010 DOI URL TARA - Full Text

Labrador, J.P., O'Keefe, D., Yoshikawa, S., McKinnon, R.D., Thomas, J.B. and Bashaw, G.J., The homeobox transcription factor even-skipped regulates netrin-receptor expression to control dorsal motor-axon projections in Drosophila. , Curr Biol, 15, (15), 2005, p1413-1419 Journal Article, 2005 TARA - Full Text URL DOI

Labrador, JP; O'Keefe, D; Yoshikawa, S; McKinnon, RD: Thomas, JB; Bashaw, GJ, The homeobox transcription factor even-skipped regulates netrin-receptor expression to control dorsal motor-axon projections in Drosophila. , Current Biology, 15, (15), 2005, p1413-1419 Journal Article, 2005 URL

Hu, H., Li, M., Labrador, J.P., McEwen, J., Lai, E.C., Goodman, C.S. and Bashaw, G.J. , Cross GTPase-activating protein (CrossGAP)/Vilse links the Roundabout receptor to Rac to regulate midline repulsion., Proceedings of the National Academy of Sciences, 102, (12), 2005, p4613-4618 Journal Article, 2005 DOI URL

Fan, X., Labrador, J.P., Hing, H. and Bashaw, G.J., Slit stimulation recruits Dock and Pak to the roundabout receptor and increases Rac activity to regulate axon repulsion at the CNS midline., Neuron, 40, (1), 2003, p113-127 Journal Article, 2003 DOI URL

Olaso, E., Labrador, J.P., Wang, L., Ikeda, K., Eng, F.J., Klein, R., Lovett, D.H., Lin, H.C. and Friedman, S.L., Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2. , J Biol Chem, 277, (5), 2002, p3606-3613 Journal Article, 2002 URL DOI

Ikeda, K., Wang, L.H., Torres, R., Zhao, H., Olaso, E., Eng, F.J., Labrador, J.P., Klein, R., Lovett, D., Yancopoulos, G.D., Friedman, S.L. and Lin, H.C. , Discoidin domain receptor 2 interacts with Src and Shc following its activation by type I collagen., J Biol Chem, 277, (21), 2002, p19206-19212. Journal Article, 2002 DOI URL

Labrador, J.P., Azcoitia, V., Tuckermann, J., Lin, C., Olaso, E., Manes, S., Bruckner, K., Goergen, J.L., Lemke, G., Yancopoulos, G., Angel, P., Martinez, C. and Klein, R., The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism., EMBO Rep, 2, (5), 2001, p446-452 Journal Article, 2001 DOI URL

Bruckner, K.*, Labrador, J.P*., Scheiffele, P*., Herb, A.*, Seeburg, P.H. and Klein, R., EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains., Neuron, 22, (3), 1999, p511-524. Journal Article, 1999 URL DOI

Manes, S., Mira, E., Gomez-Mouton, C., Lacalle, R.A., Keller, P., Labrador, J.P. and Martinez, A.C. , Membrane raft microdomains mediate front-rear polarity in migrating cells., EMBO J, 18, (22), 1999, p6211-6220 Journal Article, 1999 DOI URL

Labrador, J.P., Brambilla, R. and Klein, R., The N-terminal globular domain of Eph receptors is sufficient for ligand binding and receptor signaling., EMBO J, 16, (13), 1997, p3889-3897 Journal Article, 1997 DOI URL

Brambilla, R., Schnapp, A., Casagranda, F., Labrador, J.P., Bergemann, A.D., Flanagan, J.G., Pasquale, E.B. and Klein, R., Membrane-bound LERK2 ligand can signal through three different Eph-related receptor tyrosine kinases. , EMBO J, 14, (13), 1995, p3116-3126 Journal Article, 1995 URL