Selected Publications
1. Nolan D.P., Geuskens M., and Pays E. (1999) Current Biology 9, 1169-1172 N-linked glycans containing linear poly-N-acetyllactosamine as sorting signals in endocytosis in Trypanosoma brucei.
2. Nolan, D.P., Rolin, S., Rodriguez, J. R., Van Den Abbeele, J. and Pays, E. (2000) Eur. J. Biochem. 267, 18-27. Slender and stumpy bloodstream forms of Trypanosoma brucei display a differential response to extracellular acidic and proteolytic stress.
3. Nolan, D.P., Jackson, D.G., Biggs, M.J., Brabazon, E., Pays, A., Van Laethem, F., Paturiaux-Hanocq, F., Elliot, J.F., Voorheis, H.P. and Pays E. (2000) J. Biol. Chem. 275, 4072-4080 Characterization of a Novel Alanine-Rich Protein Located in Surface Microdomains in Trypanosoma brucei.
4. Paturiaux-Hanocq, F., Hanocq-Quertier, J., Cardoso de Almeida, L., Nolan, D.P., Pays, A., Vanhamme, L., Van den Abbeele, J., Carrington, M. and Pays, E. (2000) J. Biol. Chem. 275, 12147-12155 A role for the dynamic acylation of a cluster of cysteine residues in regulating the activity of the glycosylphosphatidylinositol-specific phospholipase C of Trypanosoma brucei.
5. Nolan, D.P., and Voorheis, H.P. (2000) Eur. J. Biochem. 267, 4601-4614 Hydrogen ion gradients across the mitochondrial, endosomal and plasma membranes in bloodstream forms of Trypanosoma brucei: solving the 3-compartment problem.
6. Nolan, D.P. and Voorheis, H.P. (2000) Eur. J. Biochem. 267, 4615-4623 Factors that determine the plasma membrane potential in bloodstream forms of Trypanosoma brucei.
7. Redpath, M.B., Windle, H., Nolan, D., Pays, E., Voorheis, H.P., and Carrington, M. (2000) Mol. Biochem. Parasitol. 111, 223-228 ESAG11, a new VSG expression site-associated gene from Trypanosoma brucei.
8. Radwanska, M., Magez, S., Dumont, N., Pays, A., Nolan, D., and Pays, E. (2000) Parasit. Immunol. 22, 639-650 Antibodies raised against the flagellar pocket fraction of Trypanosoma brucei preferentially recognize HSP60 in a cDNA expression library.
9. Nolan, D.P., Garcia Salcedo, J.-A., Vanhamme, L., and Pays, E. (2001) Communication in trypanosomatids in “Trypanosomiasis and Leishmaniasis, biology and control” (Hide G., Mottram, J.C., Coombs, G.H. and Holmes, P.H. Maudlin, I. eds.). CAB International, Oxford, pp.60-80
10. Black, S.J., N. Murphy and D. Nolan (2001) Int. J. Parasitol. 31, 562-565 Innate and acquired control of trypanosomiasis in Cape buffalo.
11. Pays, E. Lips, S., Nolan, D., Vanhamme, L., and Pérez-Morga D. (2001) Mol. Biochem. Parasitol.114,1-16 The VSG expression site of Trypanosoma brucei: multipurpose tools for the adaptation of the parasite to various mammalian hosts.
12. Nolan, DP, Garcia-Salcedo, J.A., Geuskens, M., Salmon, D., Paturiaux-Hanocq, F., Pays, A., Tebabi, P. and Pays, E. (2001) Endocytosis of macromolecules by African trypanosomes. pp127-141 In “World Class Parasites Volume 1: The African Trypanosomes” Eds. Seed, R. and Black, S.J. (Kluwer Academic Publishers)
13. Black, S.J., Murphy, N.B. and Nolan, D.P. (2001) Towards a trypanosomiasis vaccine. pp159-174 In “World Class Parasites Volume 1: The African Trypanosomes” Eds. Seed, R. and Black, S.J. (Kluwer Academic Publishers)
14. Garcia-Salcedo, J.A., Nolan, D.P., Gijon-Martin, P., Gomez, J., and Pays, E. (2002) Mol. Microbiol 45, 307-19. A protein kinase specifically associated with proliferative forms of Trypanosoma brucei is functionally related to a yeast kinase involved in the co-ordination of cell shape and division.
15. Vanhamme L, Paturiaux-Hanocq F, Poelvoorde P, Nolan DP, Lins L, Van Den Abbeele J, Pays A, Tebabi P, Van Xong H, Jacquet A, Moguilevsky N, Dieu M, Kane JP, De Baetselier P, Brasseur R, Pays E. (2003) Nature 422, 83-7 Apolipoprotein L-I is the trypanosome lytic factor of human serum.
16. García-Salcedo J.A., Gijón P., Nolan, D.P., Tebabi, P. and Pays, E. (2003) The histone ADP-ribosyl transferase activity of a trypanosomal SIR2 homologue plays a role in DNA repair. EMBO J. In press
17. Murphy, N.B., Nolan, D. and Black, S.J. (2003) Novel approaches for vaccine development against trypanosomiasis in Africa In “Biotechnology and sustainable development: voices of the south and north” Biotechnology in agriculture series No 26 (Serageldin I. And Persley, G.J. eds.). CAB International, Oxford, pp.173-18
18. García-Salcedo J.A., Perez-Morga, D., Gijón P., Dilbeek, V., Pays, E. and Nolan, D.P., (2004) A differential role for actin in the life cycle of T. brucei. EMBO J. 25:780-789.
19. Rubotham, J., Woods, K., Garcia-Salcedo, J.A., Pays, E. and Nolan, D.P. (2005) J. Biol. Chem. 280, 10410-10418 Characterization of two protein disulphide iosmerases from the endocytic pathway of Trypanosoma brucei.
20. Perez-Morga D., Vanhollebeke B., Paturiaux-Hanocq F., Nolan D.P., Lins L., Homble F., Vanhamme L., Tebabi P., Pays A., Poelvoorde P., Jacquet A., Brasseur R., Pays E. (2005) Science 309, 469-72. Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes.
21. Pays, E. Vanhamme, L., Vanhollebeke, B., Nolan, D. P.. and Perez-Morga, D. (2006) Nat Rev Microbiol. 2006 Jun;4(6):477-86. The trypanolytic factor of human serum.
22. Guimalda P, Murphy NM, Nolan D, Black SJ (2007) Int. J. Parasitol. 37: 1391-1399. Anti-Trypanosoma brucei activity I Cape Buffalo serum during the cryptic phase of parasitemia is mediated by antibodies.
23. Adams AE, Hanrahan O, Nolan DP, Voorheis HP, Fallon P, Porter RK (2008) Biochem. Biophys. Acta 1777: 115-157. Images of mitochondrial UCP 1 in mouse thymocytes using confocal microscopy
24. Nolan DP and Garcia Salcedo JA (2008) Mol. Biochem Parasitol. 157: 233-235. Loss of actin does not affect export of newly synthesized proteins to the surface of trypanosome brucei
25. Coustou V, Brian M, Guegan F, Riviere L, Plazolles N, Nolan D, Barrett MP, Franconi JM, Bringaud F.(2008). J Biol Chem. 2 in press. Glucose-induced remodelling of intermediary and energy metabolism in procyclic trypanosoma brucei.