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Molecular Parasitology

Dr Derek Nolan

Professor in Biochemistry
Course Coordinator of Junior Sophister Biochemistry

I have worked on African trypanosomes, which cause human sleeping sickness, for twenty years. As a PhD student I investigated the bioenergetics of T. brucei in Paul Voorheis' laboratory at Trinity College Dublin. Subsequently, I moved to Brussels in 1992, as an EMBO fellow, to join the group of Etienne Pays to study the expression and function of surface proteins in trypanosomes.

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Conor Leahy PhD Project 2021-2025

Aggregation of Trypanosoma brucei following the addition of IgM

Senior Sophister Project 2024/25

Video 1:GK RNAi induced SHAM treatment

Video 2:GK RNAi non-induced SHAM treatment

MSc. in Immunology Project 2022/23

Video 1: T. brucei Wild type cell

Video 2: FLA2 induced - detached flagellum


Senior Sophister Project 2022/23

Video 1: detached flagellum

Video 2: detached flagellum

Video 3: wild type cell

Video 4: wild type cell

 


The African trypanosomes are extracellular parasitic protozoa responsible for sleeping sickness in humans and related diseases in domestic animals.

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