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Professor Alan Irvine
PROFESSOR OF DERMATOLOGY, Clinical Medicine
PROFESSOR OF DERMATOLOGY, School Office - Medicine

Publications and Further Research Outputs

Peer-Reviewed Publications

Mysler, E., Burmester, G.R., Saffore, C.D., Liu, J., Wegrzyn, L., Yang, C., Betts, K.A., Wang, Y., Irvine, A.D., Panaccione, R., Safety of Upadacitinib in Immune-Mediated Inflammatory Diseases: Systematic Literature Review of Indirect and Direct Treatment Comparisons of Randomized Controlled Trials, Advances in Therapy, 2024 Journal Article, 2024

Renert-Yuval, Y., Del Duca, E., Arents, B., Bissonnette, R., Drucker, A.M., Flohr, C., Guttman-Yassky, E., Hijnen, D., Kabashima, K., Leshem, Y.A., Paller, A.S., Silverberg, J.I., Simpson, E.L., Spuls, P., Vestergaard, C., Wollenberg, A., Irvine, A.D., Thyssen, J.P., Treat-to-target in dermatology: A scoping review and International Eczema Council survey on the approach in atopic dermatitis, Journal of the European Academy of Dermatology and Venereology, 38, (1), 2024, p42-51 Journal Article, 2024

Fagan, N., Browne, F., Dvorakova, V., Carroll, A., Irvine, A.D., Getting it right the first time: an Irish paediatric dermatology perspective from a national care centre, Clinical and Experimental Dermatology, 49, (1), 2024, p61-64 Journal Article, 2024

Clowry Juliann, Dempsey Daniel J, Claxton Tracey J, Towell Aisling M, Turley Mary B, Sutton Marti, Geoghegan Joan A, Kezic Sanj, Jakasa Ivon, White Arthu, Irvine Alan D, McLoughlin Rachel M, Distinct T cell signatures are associated with Staphylococcus aureus skin infection in pediatric atopic dermatitis, 9, (9), 2024, p1-19 Journal Article, 2024 DOI URL

Paller, A.S., Flohr, C., Eichenfield, L.F., Irvine, A.D., Weisman, J., Soung, J., Pinto Correia, A., Natalie, C.R., Rodriguez Capriles, C., Pierce, E., Reifeis, S., Gontijo Lima, R., Armengol Tubau, C., Laquer, V., Weidinger, S., Safety and Efficacy of Lebrikizumab in Adolescent Patients with Moderate-to-Severe Atopic Dermatitis: A 52-Week, Open-Label, Phase 3 Study, Dermatology and Therapy, 13, (7), 2023, p1517-1534 Journal Article, 2023

Alan D. Irvine, Jonathan O'. B. Hourihane, Reply to correspondence "Food allergens to emollients", Allergy, 78, (4), 2023, p1123-1123 Journal Article, 2023

Musters, A.H., Broderick, C., Prieto-Merino, D., Chiricozzi, A., Damiani, G., Peris, K., Dhar, S., De, A., Freeman, E., Arents, B.W.M., Burton, T., Bosma, A.L.-A.L., Chi, C.-C., Fletcher, G., Drucker, A.M., Kabashima, K., de Monchy, E.F., Panda, M., Wall, D.R., Vestergaard, C., Mahé, E., Bonzano, L., Kattach, L., Napolitano, M., Ordoñez-Rubiano, M.F., Haufe, E., Patruno, C., Irvine, A.D., Spuls, P.I., Flohr, C., The effects of systemic immunomodulatory treatments on COVID-19 outcomes in patients with atopic dermatitis: Results from the global SECURE-AD registry, Journal of the European Academy of Dermatology and Venereology, 37, (2), 2023, p365-381 Journal Article, 2023

Canaud, G., Lopez Gutierrez, J.C., Irvine, A.D., Vabres, P., Hansford, J.R., Ankrah, N., Branle, F., Papadimitriou, A., Ridolfi, A., O'Connell, P., Turner, S., Adams, D.M., Alpelisib for treatment of patients with PIK3CA-related overgrowth spectrum (PROS), Genetics in Medicine, 25, (12), 2023 Journal Article, 2023

Eyerich, K., Gooderham, M.J., Silvestre, J.F., Shumack, S.P., Mendes-Bastos, P., Aoki, V., Ortoncelli, M., Silverberg, J.I., Teixeira, H.D., Chen, S.H., Calimlim, B.M., Takemoto, S., Sancho, C., Fritz, B., Irvine, A.D., Real-world clinical, psychosocial and economic burden of atopic dermatitis: Results from a multicountry study, Journal of the European Academy of Dermatology and Venereology, 2023 Journal Article, 2023

Burmester, G.R., Cohen, S.B., Winthrop, K.L., Nash, P., Irvine, A.D., Deodhar, A., Mysler, E., Tanaka, Y., Liu, J., Lacerda, A.P., Palac, H., Shaw, T., Mease, P.J., Guttman Yassky, E., Safety profile of upadacitinib over 15 000 patient-years across rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and atopic dermatitis, RMD Open, 9, (1), 2023 Journal Article, 2023

Beck, L.A., Bieber, T., Weidinger, S., Tauber, M., Saeki, H., Irvine, A.D., Eichenfield, L.F., Werfel, T., Arlert, P., Jiang, L., Røpke, M., Paller, A.S., Tralokinumab treatment improves the skin microbiota by increasing the microbial diversity in adults with moderate-to-severe atopic dermatitis: Analysis of microbial diversity in ECZTRA 1, a randomized controlled trial, Journal of the American Academy of Dermatology, 88, (4), 2023, p816-823 Journal Article, 2023

Thomas Bieber, Jacob P Thyssen, Alan D Irvine, Yuichiro Tsunemi, Yun-Fei Chen, Luna Sun, Andrea Schloebe, Elisabeth Riedl, Michael J Cork, Early improvements in signs and symptoms predict clinical response to baricitinib in patients with moderate-to-severe atopic dermatitis, Clinical and Experimental Dermatology, 48, (8), 2023, p881-888 Journal Article, 2023

Ismail, M., Doelger, E., Eckert, D., Irvine, A.D., Chu, A.D., Teixeira, H.D., Liu, W., Nader, A., Population pharmacokinetic and exposure-response modelling to inform upadacitinib dose selection in adolescent and adult patients with atopic dermatitis, British Journal of Clinical Pharmacology, 89, (10), 2023, p3139-3151 Journal Article, 2023

Siegfried, E.C., Arkin, L.M., Chiu, Y.E., Hebert, A.A., Callen, J.P., Castelo-Soccio, L., Co, D.O., Cordoro, K.M., Curran, M.L., Dalrymple, A.M., Flohr, C., Gordon, K.B., Hanna, D., Irvine, A.D., Kim, S., Kirkorian, A.Y., Lara-Corrales, I., Lindstrom, J., Paller, A.S., Reyes, M., Begolka, W.S., Tom, W.L., Van Voorhees, A.S., Vleugels, R.A., Lee, L.W., Davies, O.M.T., Brandling-Bennett, H.A., Methotrexate for inflammatory skin disease in pediatric patients: Consensus treatment guidelines, Pediatric Dermatology, 40, (5), 2023, p789-808 Journal Article, 2023

Cathal O'Connor, Vicki Livingstone, Jonathan O"B Hourihane, Alan D. Irvine, Geraldine Boylan, Deirdre Murray, Early emollient bathing is associated with subsequent atopic dermatitis in an unselected birth cohort study, Pediatric Allergy and Immunology, 34, (7), 2023 Journal Article, 2023

Zuberbier, T., Abdul Latiff, A., Aggelidis, X., Augustin, M., Balan, R.-G., Bangert, C., Beck, L., Bieber, T., Bernstein, J.A., Bertolin Colilla, M., Berardi, A., Bedbrook, A., Bindslev-Jensen, C., Bousquet, J., de Bruin-Weller, M., Bruscky, D., Buyuktiryaki, B., Canonica, G.W., Castro, C., Chanturidze, N., Chong-Neto, H.J., Chu, C.-Y., Chularojanamontri, L., Cork, M., Criado, R.F.J., Barredo, L.C., Custovic, A., Darsow, U., Emurlai, A., de Pablo, A., Del Giacco, S., Girolomoni, G., Deleva Jovanova, T., Deleuran, M., Douladiris, N., Duarte, B., Dubakiene, R., Eller, E., Engel-Yeger, B., Ensina, L.F., Filho, N.R., Flohr, C., Fomina, D., Francuzik, W., Galimberti, M.L., Giménez-Arnau, A.M., Godse, K., Mortz, C.G., Gotua, M., Hide, M., Hoetzenecker, W., Hunzelmann, N., Irvine, A., Jack, C., Kanavarou, I., Katoh, N., Kinaciyan, T., Kocatürk, E., Kulthanan, K., Lapeere, H., Lau, S., Machado Forti Nastri, M., Makris, M., Mansour, E., Marsland, A., Morelo Rocha Felix, M., Moschione Castro, A.P., Nettis, E., Nicolas, J.F., Nosbaum, A., Odemyr, M., Papapostolou, N., Parisi, C.A.S., Paudel, S., Peter, J., Pokharel, P., Puig, L., Quint, T., Ramon, G.D., Regateiro, F., Ricci, G., Rosario, C., Sackesen, C., Schmid-Grendelmeier, P., Serra-Baldrich, E., Siemens, K., Smith, C., Staubach, P., Stevanovic, K., Su-Kücük, Ö., Sussman, G., Tavecchio, S., Teovska Mitrevska, N., Thaci, D., Toubi, E., Traidl-Hoffmann, C., Treudler, R., Vadasz, Z., van Hofman, I., Ventura, M.T., Wang, Z., Werfel, T., Wollenberg, A., Yang, A., Weng Yew, Y., Zhao, Z., Zwiener, R., Worm, M., A concept for integrated care pathways for atopic dermatitis"A GA2LEN ADCARE initiative, Clinical and Translational Allergy, 13, (9), 2023 Journal Article, 2023

Flohr, C., Rosala-Hallas, A., Jones, A.P., Beattie, P., Baron, S., Browne, F., Brown, S.J., Gach, J.E., Greenblatt, D., Hearn, R., Hilger, E., Esdaile, B., Cork, M.J., Howard, E., Lovgren, M.-L., August, S., Ashoor, F., Williamson, P.R., McPherson, T., O"Kane, D., Ravenscroft, J., Shaw, L., Sinha, M.D., Spowart, C., Taams, L.S., Thomas, B.R., Wan, M., Sach, T.H., Irvine, A.D., Efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children and young people (TREAT): A multicentre parallel group assessor-blinded clinical trial, British Journal of Dermatology, 189, (6), 2023, p674-684 Journal Article, 2023

Guttman-Yassky, E., Irvine, A.D., Brunner, P.M., Kim, B.S., Boguniewicz, M., Parmentier, J., Platt, A.M., Kabashima, K., The role of Janus kinase signaling in the pathology of atopic dermatitis, Journal of Allergy and Clinical Immunology, 152, (6), 2023, p1394-1404 Journal Article, 2023

Duggan, C., Irvine, A.D., O"B Hourihane, J., Kiely, M.E., Murray, D.M., ASQ-3 and BSID-III"s concurrent validity and predictive ability of cognitive outcome at 5 years, Pediatric Research, 94, (4), 2023, p1465-1471 Journal Article, 2023

Paller, A.S., Ladizinski, B., Mendes-Bastos, P., Siegfried, E., Soong, W., Prajapati, V.H., Lio, P., Thyssen, J.P., Simpson, E.L., Platt, A.M., Raymundo, E.M., Liu, J., Calimlim, B.M., Huang, X., Gu, Y., Hu, X., Yang, Y., Su, J.C., Zheng, M., Yamamoto-Hanada, K., Teixeira, H.D., Irvine, A.D., Efficacy and Safety of Upadacitinib Treatment in Adolescents with Moderate-to-Severe Atopic Dermatitis: Analysis of the Measure Up 1, Measure Up 2, and AD Up Randomized Clinical Trials, JAMA Dermatology, 159, (5), 2023, p526-535 Journal Article, 2023

Paller, A.S., Silverberg, J.I., Cork, M.J., Guttman-Yassky, E., Lockshin, B., Irvine, A.D., Kim, M.B., Kabashima, K., Chen, Z., Lu, Y., Bansal, A., Rossi, A.B., Shabbir, A., Efficacy and Safety of Dupilumab in Patients with Erythrodermic Atopic Dermatitis: A Post Hoc Analysis of 6 Randomized Clinical Trials, JAMA Dermatology, 159, (3), 2023, p255-266 Journal Article, 2023

Nousbeck, Janna, McAleer, Maeve A., Irvine, Alan D., Peripheral Blood Gene Expression Profile of Infants with Atopic Dermatitis, JID Innovations, 3, (2), 2023, p100165 Journal Article, 2023 DOI

Guttman-Yassky, E., Thyssen, J.P., Silverberg, J.I., Papp, K.A., Paller, A.S., Weidinger, S., Chih-ho Hong, H., Hendrickson, B., Dilley, D., Tenorio, A.R., Ladizinski, B., Chu, A.D., Liu, J., Irvine, A.D., Safety of upadacitinib in moderate-to-severe atopic dermatitis: An integrated analysis of phase 3 studies, Journal of Allergy and Clinical Immunology, 151, (1), 2023, p172-181 Journal Article, 2023

Carsten Flohr, Alan D Irvine, Michael J Cork, Eric L Simpson, Andreas Wollenberg, Mette Deleuran, Amy  Praestgaard, Ryan B Thomas, Ana B Rossi, Dupilumab improves patient-reported symptoms and health-related quality of life in children aged 6"11 years with severe atopic dermatitis, British Journal of Dermatology, 189, (2), 2023, p238-240 Journal Article, 2023

Silverberg, J.I., Guttman-Yassky, E., Thaçi, D., Irvine, A.D., Stein Gold, L., Blauvelt, A., Simpson, E.L., Chu, C.-Y., Liu, Z., Gontijo Lima, R., Pillai, S.G., Seneschal, J., Two Phase 3 Trials of Lebrikizumab for Moderate-to-Severe Atopic Dermatitis, New England Journal of Medicine, 388, (12), 2023, p1080-1091 Journal Article, 2023

Bieber, T., Feist, E., Irvine, A.D., Harigai, M., Haladyj, E., Ball, S., Deberdt, W., Issa, M., Grond, S., Taylor, P.C., Correction to: A Review of Safety Outcomes from Clinical Trials of Baricitinib in Rheumatology, Dermatology and COVID-19 (Advances in Therapy, (2022), 39, 11, (4910-4960), 10.1007/s12325-022-02281-4), Advances in Therapy, 40, (9), 2023, p4114-4115 Journal Article, 2023

Walsh, Carleen, Leavey, Gerard, Mc Laughlin, Marian, Paller, Amy S, Irvine, Alan D, Browne, Fiona, Mellerio, Jemima E, Bewley, Anthony, Novel mixed-method, inclusive protocol involving global key stakeholders, including carers as experts, to co-develop relevant Caregiver-Reported Outcome Domains (CRODs) in skin disease, BMJ Open, 13, (1), 2023, pe068893 Journal Article, 2023 DOI

Nicole Fagan, Fiona Browne, Veronika Dvorakova, Áine Carroll, Alan D Irvine, `Guidelines are not the issue, access to support and advice is the problem": a cross-sectional survey of general practitioners referring to paediatric dermatology, Clinical and Experimental Dermatology, 49, (1), 2023, p71-72 Journal Article, 2023

Alan D. Irvine, Thishi Surendranathan, Liz Hennessy, Ivana Rajkovic, Annette Durkan, Dearbhla Coughlan, Sean Conlon, Richard Hudson, A real"world retrospective observational study exploring resource use for secondary care management of moderate"to"severe atopic dermatitis in children and adolescents at a single site in Ireland, JEADV Clinical Practice, 2, (3), 2023, p465-478 Journal Article, 2023

Bosma, A.L., Ouwerkerk, W., Heidema, M.J., Prieto-Merino, D., Ardern-Jones, M.R., Beattie, P., Brown, S.J., Ingram, J.R., Irvine, A.D., Ogg, G., Patel, P., Reynolds, N.J., Hearn, R.M.R., Wan, M., Warren, R.B., Woolf, R.T., Hyseni, A.M., Gerbens, L.A.A., Spuls, P.I., Flohr, C., Middelkamp-Hup, M.A., Comparison of real-world treatment outcomes of systemic immunomodulating therapy in atopic dermatitis patients with dark and light skin types, JAAD International, 10, 2023, p14-24 Journal Article, 2023

Augustin, M., Nosbaum, A., Werfel, T., Grond, S., Reed, C., Lampropoulou, A., Tietz, N., Irvine, A.D., Riedl, E., Treatment satisfaction of adult patients with moderate-to-severe atopic dermatitis treated with baricitinib in France, Germany, and the United Kingdom: results from a cross-sectional international patient survey, Journal of Dermatological Treatment, 34, (1), 2023 Journal Article, 2023

Carol Ní Chaoimh, Dhanis Lad, Claudio Nico, Gerwin J. Puppels, X. F. Colin C. Wong, John E. Common, Deirdre M. Murray, Alan D. Irvine, Jonathan O"Brien Hourihane, Early initiation of short"term emollient use for the prevention of atopic dermatitis in high"risk infants"The STOP"AD randomised controlled trial, Allergy, 78, (4), 2023, p984-994 Journal Article, 2023

Mussa, Alessandro, Leoni, Chiara, Iacoviello, Matteo, Carli, Diana, Ranieri, Carlotta, Pantaleo, Antonino, Buonuomo, Paola Sabrina, Bagnulo, Rosanna, Ferrero, Giovanni Battista, Bartuli, Andrea, Melis, Daniela, Maitz, Silvia, Loconte, Daria Carmela, Turchiano, Antonella, Piglionica, Marilidia, De Luisi, Annunziata, Susca, Francesco Claudio, Bukvic, Nenad, Forleo, Cinzia, Selicorni, Angelo, Zampino, Giuseppe, Onesimo, Roberta, Cappuccio, Gerarda, Garavelli, Livia, Novelli, Chiara, Memo, Luigi, Morando, Carla, Della Monica, Matteo, Accadia, Maria, Capurso, Martina, Piscopo, Carmelo, Cereda, Anna, Di Giacomo, Marilena Carmela, Saletti, Veronica, Spinelli, Alessandro Mauro, Lastella, Patrizia, Tenconi, Romano, Dvorakova, Veronika, Irvine, Alan D., Resta, Nicoletta, Genotypes and phenotypes heterogeneity in PIK3CA-related overgrowth spectrum and overlapping conditions: 150 novel patients and systematic review of 1007 patients with PIK3CA pathogenetic variants, Journal of Medical Genetics, 60, (2), 2023, p163-173 Journal Article, 2023

Kezic, S., McAleer, M.A., Jakasa, I., Goorden, S.M.I., der Vlugt, K.G.-V., Beers-Stet, F.S., Meijer, J., Roelofsen, J., Nieman, M.M., van Kuilenburg, A.B.P., Irvine, A.D., Children with atopic dermatitis show increased activity of ß-glucocerebrosidase and stratum corneum levels of glucosylcholesterol that are strongly related to the local cytokine milieu, British Journal of Dermatology, 186, (6), 2022, p988-996 Journal Article, 2022

Takuya Miyano, Alan D. Irvine, Reiko J. Tanaka, Model-Based Meta-Analysis to Optimize Staphylococcus aureus"Targeted Therapies for Atopic Dermatitis, JID Innovations, 2, (3), 2022, p100110 Journal Article, 2022

Ghaffarpour, N., Baselga, E., Boon, L.M., Diociaiuti, A., Dompmartin, A., Dvorakova, V., El Hachem, M., Gasparella, P., Haxhija, E., Kyrklund, K., Irvine, A.D., Kapp, F.G., Rößler, J., Salminen, P., van den Bosch, C., van der Vleuten, C., Kool, L.S., Vikkula, M., The VASCERN-VASCA working group diagnostic and management pathways for lymphatic malformations, European Journal of Medical Genetics, 65, (12), 2022 Journal Article, 2022

Nicholas Stefanovic, Conor J. Fitzmaurice, Patrick Ormond, Alan D. Irvine, Rupert B. Barry, Risk factors for distant metastasis in cutaneous squamous cell carcinoma, British Journal of Dermatology, 187, (3), 2022, p435-436 Journal Article, 2022

Cathal O"Connor, Alan D. Irvine, Deirdre Murray, Michelle Murphy, Jonathan O"B Hourihane, Geraldine Boylan, Study protocol: assessing SleeP IN infants with early-onset atopic Dermatitis by Longitudinal Evaluation (The SPINDLE study), BMC Pediatrics, 22, (1), 2022 Journal Article, 2022

Werfel, T., Irvine, A.D., Bangert, C., Seneschal, J., Grond, S., Cardillo, T., Brinker, D., Zhong, J., Riedl, E., Wollenberg, A., An integrated analysis of herpes virus infections from eight randomized clinical studies of baricitinib in adults with moderate-to-severe atopic dermatitis, Journal of the European Academy of Dermatology and Venereology, 36, (9), 2022, p1486-1496 Journal Article, 2022

Bieber, T., Feist, E., Irvine, A.D., Harigai, M., Haladyj, E., Ball, S., Deberdt, W., Issa, M., Grond, S., Taylor, P.C., A Review of Safety Outcomes from Clinical Trials of Baricitinib in Rheumatology, Dermatology and COVID-19, Advances in Therapy, 39, (11), 2022, p4910-4960 Journal Article, 2022

Cox F, Bigley V, Irvine A, Leahy R, Conlon N., PAMI Syndrome: Two Cases of an Autoinflammatory Disease with an ALPS-Like Phenotype., Journal of clinical immunology, 42, (5), 2022, p955-958 Journal Article, 2022 DOI

Budu-Aggrey, A., Kilanowski, A., Sobczyk, M.K., Shringarpure, S.S., Mitchell, R., Reis, K., Reigo, A., Mägi, R., Nelis, M., Tanaka, N., Brumpton, B.M., Thomas, L.F., Sole-Navais, P., Flatley, C., Espuela-Ortiz, A., Herrera-Luis, E., Lominchar, J.V.T., Bork-Jensen, J., Marenholz, I., Arnau-Soler, A., Jeong, A., Fawcett, K.A., Baurecht, H., Rodriguez, E., Alves, A.C., Kumar, A., Sleiman, P.M., Chang, X., Medina-Gomez, C., Hu, C., Xu, C.-J., Qi, C., El-Heis, S., Titcombe, P., Antoun, E., Fadista, J., Wang, C.A., Thiering, E., Xiao, S., Kress, S., Kothalawala, D.M., Kadalayil, L., Duan, J., Zhang, H., Hoffmann, T., Jorgenson, E., Choquet, H., Risch, N., Njølstad, P., Andreassen, O.A., Johansson, S., Almqvist, C., Gong, T., Ullemar, V., Karlsson, R., Magnusson, P.K.E., Szwajda, A., Burchard, E.G., Thyssen, J.P., Hansen, T., Kårhus, L.L., Dantoft, T.M., Jeanrenaud, A.C.S.N., Ghauri, A., Arnold, A., Homuth, G., Lau, S., Nöthen, M.M., Hübner, N., Imboden, M., Visconti, A., Falchi, M., Bataille, V., Hysi, P., Ballardini, N., Boomsma, D.I., Hottenga, J.J., Müller-Nurasyid, M., Ahluwalia, T.S., Stokholm, J., Chawes, B., Schoos, A.-M., Esplugues, A., Bustamante, M., Raby, B., Arshad, H., German, C., Esko, T., Milani, L.A., Metspalu, A., Terao, C., Abuabara, K., Løset, M., Hveem, K., Jacobsson, B., Pino-Yanes, M., Strachan, D.P., Grarup, N., Linneberg, A., Lee, Y.-A., Probst-Hensch, N., Weidinger, S., Jarvelin, M.-R., Melén, E., Hakonarson, H., Irvine, A.D., Jarvis, D.L., Nijsten, T., Duijts, L., Vonk, J.M., Koppelmann, G.H., Godfrey, K.M., Barton, S.J., Feenstra, B., Pennell, C.E., Sly, P.D., Holt, P.G., Williams, K.L., Bisgaard, H., Bønnelykke, K., Curtin, J., Simpson, A., Murray, C., Schikowski, T., Bunyavanich, S., Weiss, S.T., Holloway, J.W., Min, J., Brown, S.J., Standl, M., Paternoster, L., European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation, medRxiv, 2022 Journal Article, 2022

Diociaiuti, A., Baselga, E., Boon, L.M., Dompmartin, A., Dvorakova, V., El Hachem, M., Gasparella, P., Haxhija, E., Ghaffarpour, N., Kyrklund, K., Irvine, A.D., Kapp, F.G., Rößler, J., Salminen, P., van den Bosch, C., van der Vleuten, C., Kool, L.S., Vikkula, M., The VASCERN-VASCA working group diagnostic and management pathways for severe and/or rare infantile hemangiomas, European Journal of Medical Genetics, 65, (6), 2022 Journal Article, 2022

Paller, A.S., Guttman-Yassky, E., Schuttelaar, M.L.A., Irvine, A.D., Baselga, E., Kataoka, Y., Antila, M., de Bruin-Weller, M.S., Marcoux, D., Abramova, A., Rizova, E., Liu, C., Zhang, A., Disease characteristics, comorbidities, treatment patterns and quality of life impact in children <12 years old with atopic dermatitis: Interim results from the PEDISTAD Real-World Registry, Journal of the American Academy of Dermatology, 87, (5), 2022, p1104-1108 Journal Article, 2022

Cathal O'Connor, Vicki Livingstone, Jonathan O'. B. Hourihane, Alan D. Irvine, Geraldine Boylan, Deirdre Murray, Parental atopy and risk of atopic dermatitis in the first two years of life in the BASELINE birth cohort study, Pediatric Dermatology, 2022 Journal Article, 2022

Guttman-Yassky, Emma, Teixeira, Henrique D, Simpson, Eric L, Papp, Kim A, Pangan, Aileen L, Blauvelt, Andrew, Thaçi, Diamant, Chu, Chia-Yu, Hong, H Chih-ho, Katoh, Norito, Paller, Amy S, Calimlim, Brian, Gu, Yihua, Hu, Xiaofei, Liu, Meng, Yang, Yang, Liu, John, Tenorio, Allan R, Chu, Alvina D, Irvine, Alan D, Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double-blind, randomised controlled phase 3 trials, The Lancet, 397, (10290), 2021, p2151-2168 Journal Article, 2021 DOI

Wall, Dmitri, Meah, Nekma, York, Katherine, Bhoyrul, Bevin, Bokhari, Laita, Abraham, Leonardo Spagnol, Adams, Roisín, Bergfeld, Wilma, Betz, Regina C., Blume-Peytavi, Ulrike, Callender, Valerie, Campbell, Chel, Chambers, Jen, Chen, Gang, Chitreddy, Vijaya, Cotsarelis, George, Craiglow, Brittany, Dhurat, Rachita, Dlova, Ncoza, Donovan, Jeff, Duque-Estrada, Bruna, Eisman, Samantha, Ellison, Abby, Farrant, Paul, Barberá, Juan Ferrando, Gadzhigoroeva, Aida, Grimalt, Ramon, Harries, Matthew, Hordinsky, Maria, Irvine, Alan D., Jolliffe, Victoria, Jones, Leslie, King, Brett, Lee, Won-Soo, Lortkipanidze, Nino, McMichael, Amy, Messenger, Andrew, Mirmirani, Paradi, Olsen, Elise, Orlow, Seth J., Ovcharenko, Yuliya, Piraccini, Bianca Maria, Pirmez, Rodrigo, Rakowska, Adriana, Reygagne, Pascal, Riley, Melissa, Rudnicka, Lidia, Saceda Corralo, David, Shapiro, Jerry, Sharma, Pooja, Silyuk, Tatiana, Kaiumov, Spartak, Tobin, Desmond J., Tosti, Antonella, Vañó-Galván, Sergio, Vogt, Annika, Wade, Martin, Yip, Leona, Zlotogorski, Abraham, Zhou, Cheng, Sinclair, Rodney, A Global eDelphi Exercise to Identify Core Domains and Domain Items for the Development of a Global Registry of Alopecia Areata Disease Severity and Treatment Safety (GRASS), JAMA Dermatology, 157, (4), 2021, p439 Journal Article, 2021 DOI

Stefanovic, Nicholas, Irvine, Alan D., Flohr, Carsten, The Role of the Environment and Exposome in Atopic Dermatitis, Current Treatment Options in Allergy, 8, (3), 2021, p222-241 Journal Article, 2021 DOI

McCarthy, Elaine K, Murray, Deirdre M, Hourihane, Jonathan O"B, Kenny, Louise C, Irvine, Alan D, Kiely, Mairead E, Behavioral consequences at 5 y of neonatal iron deficiency in a low-risk maternal"infant cohort, The American Journal of Clinical Nutrition, 113, (4), 2021, p1032-1041 Journal Article, 2021 DOI

Meah, Nekma, Wall, Dmitri, York, Katherine, Bhoyrul, Bevin, Bokhari, Laita, Asz-Sigall, Daniel, Bergfeld, Wilma F., Betz, Regina C., Blume-Peytavi, Ulrike, Callender, Valerie, Chitreddy, Vijaya, Combalia, Andrea, Cotsarelis, George, Craiglow, Brittany, Donovan, Jeff, Eisman, Samantha, Farrant, Paul, Green, Jack, Grimalt, Ramon, Harries, Matthew, Hordinsky, Maria, Irvine, Alan D., Itami, Satoshi, Jolliffe, Victoria, King, Brett, Lee, Won-Soo, McMichael, Amy, Messenger, Andrew, Mirmirani, Paradi, Olsen, Elise, Orlow, Seth J., Piraccini, Bianca Maria, Rakowska, Adriana, Reygagne, Pascal, Roberts, Janet L., Rudnicka, Lidia, Shapiro, Jerry, Sharma, Pooja, Tosti, Antonella, Vogt, Annika, Wade, Martin, Yip, Leona, Zlotogorski, Abraham, Sinclair, Rodney D., The Alopecia Areata Consensus of Experts (ACE) study part II: Results of an international expert opinion on diagnosis and laboratory evaluation for alopecia areata, Journal of the American Academy of Dermatology, 84, (6), 2021, p1594-1601 Journal Article, 2021 DOI

Wall, Dmitri, Alhusayen, Raed, Arents, Bernd, Apfelbacher, Christian, Balogh, Esther A., Bokhari, Laita, Bloem, Manja, Bosma, Angela L., Burton, Tim, Castelo-Soccio, Leslie, Fagan, Nicole, Feldman, Steven R., Fletcher, Godfrey, Flohr, Carsten, Freeman, Esther, French, Lars E., Griffiths, Christopher E.M., Hruza, George J., Ingram, John R., Kappelman, Michael D., Lara-Corrales, Irene, Lim, Henry W., Meah, Nekma, McMahon, Devon E., Mahil, Satveer K., McNicoll, Ian, Musters, Annelie, Naik, Haley B., Sinclair, Rodney, Smith, Catherine H., Spuls, Phyllis, Tobin, Desmond J., York, Katherine, Irvine, Alan D., Learning from disease registries during a pandemic: Moving toward an international federation of patient registries, Clinics in Dermatology, 39, (3), 2021, p467-478 Journal Article, 2021 DOI

Takuya Miyano, Alan D Irvine, Reiko J Tanaka, A mathematical model to identify optimal combinations of drug targets for dupilumab poor responders in atopic dermatitis, 2021 Journal Article, 2021

Hotz, Alrun, Kopp, Julia, Bourrat, Emmanuelle, Oji, Vinzenz, Komlosi, Katalin, Giehl, Kathrin, Bouadjar, Bakar, Bygum, Anette, Tantcheva-Poor, Iliana, Hellström Pigg, Maritta, Has, Cristina, Yang, Zhou, Irvine, Alan D., Betz, Regina C., Zambruno, Giovanna, Tadini, Gianluca, Süßmuth, Kira, Gruber, Robert, Schmuth, Matthias, Mazereeuw-Hautier, Juliette, Jonca, Natalie, Guez, Sophie, Brena, Michela, Hernandez-Martin, Angela, van den Akker, Peter, Bolling, Maria C., Hannula-Jouppi, Katariina, Zimmer, Andreas D., Alter, Svenja, Vahlquist, Anders, Fischer, Judith, Meta-Analysis of Mutations in ALOX12B or ALOXE3 Identified in a Large Cohort of 224 Patients, Genes, 12, (1), 2021, p80 Journal Article, 2021 DOI

Xing, Chao, Kanchwala, Mohammed, Rios, Jonathan J., Hyatt, Tommy, Wang, Richard C., Tran, An, Dougherty, Irene, Tovar"Garza, Andrea, Purnadi, Christy, Kumar, Monique G., Berk, David, Shinawi, Marwan, Irvine, Alan D., Toledo"Bahena, Mirna, Agim, Nnenna G., Glass, Donald A., Biallelic variants in RNU12 cause CDAGS syndrome, Human Mutation, 42, (8), 2021, p1042-1052 Journal Article, 2021 DOI

Towell AM, Feuillie C, Vitry P, Da Costa TM, Mathelié-Guinlet M, Kezic S, Fleury OM, McAleer MA, Dufrêne YF, Irvine AD, Geoghegan JA, Staphylococcus aureus binds to the N-terminal region of corneodesmosin to adhere to the stratum corneum in atopic dermatitis, Proceedings of the National Academy of Sciences of the United States of America, 118, (1), 2021, pe2014444118 Journal Article, 2021 URL

Freeman, Esther E., Chamberlin, Grace C., McMahon, Devon E., Hruza, George J., Wall, Dmitri, Meah, Nekma, Sinclair, Rodney, Balogh, Esther A., Feldman, Steven R., Lowes, Michelle A., Marzano, Angelo V., Naik, Haley B., Castelo-Soccio, Leslie, Lara-Corrales, Irene, Cordoro, Kelly M., Mahil, Satveer K., Griffiths, Christopher E.M., Smith, Catherine H., Irvine, Alan D., Spuls, Phyllis I., Flohr, Carsten, French, Lars E., Dermatology COVID-19 Registries, Dermatologic Clinics, 39, (4), 2021, p575-585 Journal Article, 2021 DOI

Silverberg, Jonathan I., Simpson, Eric L., Armstrong, April W., de Bruin-Weller, Marjolein S., Irvine, Alan D., Reich, Kristian, Expert Perspectives on Key Parameters that Impact Interpretation of Randomized Clinical Trials in Moderate-to-Severe Atopic Dermatitis, American Journal of Clinical Dermatology, 2021 Journal Article, 2021 DOI

Lucy E. Bradshaw, Rachel H. Haines, Kim S. Thomas, Joanne R. Chalmers, Alan D. Irvine, Hywel C. Williams, Sara J. Brown, Clinical examination for hyperlinear palms to determine filaggrin genotype: A diagnostic test accuracy study, Clinical & Experimental Allergy, 2021 Journal Article, 2021 DOI

Delles, C, Dayan, C M, Dominiczak, A F, Donnelly, S C, Irvine, A D, Announcing the first AoP webinar: `Can evidence-based medicine survive in a pandemic?", QJM: An International Journal of Medicine, 114, (1), 2021, p11-12 Journal Article, 2021 DOI

Bradshaw, Lucy E., Haines, Rachel H., Thomas, Kim S., Chalmers, Joanne R., Irvine, Alan D., Williams, Hywel C., Brown, Sara J., Clinical examination for hyperlinear palms to determine filaggrin genotype: A diagnostic test accuracy study, Clinical & Experimental Allergy, 51, (11), 2021, p1421-1428 Journal Article, 2021 DOI

A.R. Mulick, K.E. Mansfield, R.J. Silverwood, A. Budu"Aggrey, A. Roberts, A. Custovic, N. Pearce, A.D. Irvine, L. Smeeth, K. Abuabara, S.M. Langan, Four childhood atopic dermatitis subtypes identified from trajectory and severity of disease and internally validated in a large UK birth cohort, British Journal of Dermatology, 185, (3), 2021, p526--536 Journal Article, 2021 DOI

Takuya Miyano, Alan D Irvine, Reiko J Tanaka, Model-based meta-analysis to optimise S. aureus-targeted therapies for atopic dermatitis, 2021 Journal Article, 2021 DOI

Onoufriadis, A., Cabezas, A., Ng, J.C.F., Canales, J., Costas, M.J., Ribeiro, J.M., Rodrigues, J.R., McAleer, M.A., Castelo"Soccio, L., Simpson, M.A., Fraternali, F., Irvine, A.D., Cameselle, J.C., McGrath, J.A., Autosomal recessive hypotrichosis with loose anagen hairs associated with TKFC mutations*, British Journal of Dermatology, 184, (5), 2021, p935-943 Journal Article, 2021 DOI

Jennifer M. E. Boggs, Alan D. Irvine, PLACK syndrome resulting from a novel homozygous variant in CAST, Pediatric Dermatology, 2021 Journal Article, 2021

Holm, Annegret, te Loo, Maroeska, Schultze Kool, Leo, Salminen, Päivi, Celis, Veronica, Baselga, Eulalia, Duignan, Sophie, Dvorakova, Veronika, Irvine, Alan D., Boon, Laurence M., Vikkula, Miikka, Ghaffarpour, Nader, Niemeyer, Charlotte M., Rössler, Jochen, Kapp, Friedrich G., Efficacy of Sirolimus in Patients Requiring Tracheostomy for Life-Threatening Lymphatic Malformation of the Head and Neck: A Report From the European Reference Network, Frontiers in Pediatrics, 9, 2021 Journal Article, 2021 DOI

Doherty AM, Colleran GC, Durcan L, Irvine AD, Barrett E, A pilot study of burnout and long covid in senior specialist doctors., Irish journal of medical science, 2021 Journal Article, 2021

Deleuran, M, Marcoux, D, Bruin-Weller, M, Irvine, A, Baselga, E, Ahn, K, Castro, A, Bansal, A, Chao, J, Bégo-Le-Bagousse, G, Rossi, A, Dupilumab Provides Significant Clinical Benefit in a Phase 3 Trial in Adolescents with Uncontrolled Atopic Dermatitis Irrespective of Prior Systemic Immunosuppressant Use, Acta Dermato Venereologica, 101, (7), 2021, padv00504 Journal Article, 2021 DOI

Abuabara, K., Nicholls, S.G., Langan, S.M., Guttman"Yassky, E., Reynolds, N.J., Paller, A.S., Brown, S.J., , , Priority research questions in atopic dermatitis: an International Eczema Council eDelphi consensus, British Journal of Dermatology, 185, (1), 2021, p203-205 Journal Article, 2021 DOI

Mulick, A.R., Mansfield, K.E., Silverwood, R.J., Budu"Aggrey, A., Roberts, A., Custovic, A., Pearce, N., Irvine, A.D., Smeeth, L., Abuabara, K., Langan, S.M., Four childhood atopic dermatitis subtypes identified from trajectory and severity of disease and internally validated in a large UK birth cohort, British Journal of Dermatology, 185, (3), 2021, p526-536 Journal Article, 2021 DOI

Fagan, Nicole, Meah, Nekma, York, Katherine, Bokhari, Laita, Fletcher, Godfrey, Chen, Gang, Tobin, Desmond J., Messenger, Andrew, Irvine, Alan D., Sinclair, Rodney, Wall, Dmitri, Shedding light on therapeutics in alopecia and their relevance to COVID-19, Clinics in Dermatology, 39, (1), 2021, p76-83 Journal Article, 2021 DOI

Luger, T., Paller, A.S., Irvine, A.D., Sidbury, R., Eichenfield, L.F., Werfel, T., Bieber, T., Topical therapy of atopic dermatitis with a focus on pimecrolimus, Journal of the European Academy of Dermatology and Venereology, 35, (7), 2021, p1505-1518 Journal Article, 2021 DOI

Drislane, C., Irvine, A.D., The role of filaggrin in atopic dermatitis and allergic disease, Annals of Allergy, Asthma and Immunology, 124, (1), 2020, p36-43 Journal Article, 2020

Karina Forde, Nicoletta Resta, Carlotta Ranieri, David Rea, Olga Kubassova, Mark Hinton, Alan D Irvine, Veronika Dvorakova, Clinical Experience with the AKT1 Inhibitor Miransertib in two Children with PIK3CA-related overgrowth syndrome, 2020 Journal Article, 2020

F.M. Vermeulen, L.A.A. Gerbens, J. Schmitt, M. Deleuran, A.D. Irvine, K. Logan, W. Ouwerkerk, C. Vestergaard, C. Flohr, P.I. Spuls, The European TREatment of ATopic eczema (TREAT) Registry Taskforce survey: prescribing practices in Europe for phototherapy and systemic therapy in adult patients with moderate"to"severe atopic eczema*, British Journal of Dermatology, 2020 Journal Article, 2020

H. Blakeway, V. Van"de"Velde, V.B. Allen, G. Kravvas, L. Palla, M.J. Page, C. Flohr, R.B. Weller, A.D. Irvine, T. McPherson, A. Roberts, H.C. Williams, N. Reynolds, S.J. Brown, L. Paternoster, S.M. Langan, What is the evidence for interactions between filaggrin null mutations and environmental exposures in the aetiology of atopic dermatitis? A systematic review, British Journal of Dermatology, 2020 Journal Article, 2020

M.A. McAleer, I. Jakasa, N. Stefanovic, W.H.I. McLean, S. Kezic, A.D. Irvine, Topical Corticosteroids Normalize both Skin and Systemic Inflammatory Markers in Infant Atopic Dermatitis, British Journal of Dermatology, 2020 Journal Article, 2020

L. Cunningham, V. Dvorakova, F. Browne, A.D. Irvine, High dose Bilastine for the treatment of Bascule Syndrome, Clinical and Experimental Dermatology, 2020 Journal Article, 2020

J. Nousbeck, M.A. McAleer, G. Hurault, E. Kenny, K. Harte, S. Kezic, R.J. Tanaka, A.D. Irvine, MicroRNA analysis of childhood atopic dermatitis reveals a role for miR"451a, British Journal of Dermatology, 2020 Journal Article, 2020

Doreen Siegels, Annice Heratizadeh, Susanne Abraham, Jonas Binnmyr, Knut Brockow, Alan D. Irvine, Susanne Halken, Charlotte G Mortz, Carsten Flohr, Peter Schmid"Grendelmeier, Lauri"Ann Poel, Antonella Muraro, Stephan Weidinger, Thomas Werfel, Jochen Schmitt, Systemic treatments in the management of atopic dermatitis: A systematic review and meta"analysis, Allergy, 2020 Journal Article, 2020

Marek Haftek, Maeve A McAleer, Ivone Jakasa, WH Irwin McLean, Sanja Kezic, Alan D. Irvine, Changes in nano-mechanical properties of human epidermal cornified cells in children with atopic dermatitis, Wellcome Open Research, 5, 2020, p97 Journal Article, 2020

Paller, A.S., Kong, H.H., Seed, P., Naik, S., Scharschmidt, T.C., Gallo, R.L., Luger, T., Irvine, A.D., The microbiome in patients with atopic dermatitis, Journal of Allergy and Clinical Immunology, 143, (1), 2019, p26-35 Journal Article, 2019

Hawkes, C.P., Grimberg, A., Kenny, L.C., Kiely, M., Hourihane, J.O.B., Irvine, A.D., McPhaul, M.J., Caulfield, M.P., Zemel, B.S., Murray, D.M., The relationship between IGF-I and -II concentrations and body composition at birth and over the first 2 months, Pediatric Research, 85, (5), 2019, p687-692 Journal Article, 2019

Revencu, N., Fastre, E., Ravoet, M., Helaers, R., Brouillard, P., Bisdorff-Bresson, A., Chung, C.W.T., Gerard, M., Dvorakova, V., Irvine, A.D., Boon, L.M., Vikkula, M., RASA1 mosaic mutations in patients with capillary malformation-arteriovenous malformation, Journal of Medical Genetics, 2019 Journal Article, 2019

Harkins, C.P., Holden, M.T.G., Irvine, A.D., Antimicrobial resistance in atopic dermatitis: Need for an urgent rethink, Annals of Allergy, Asthma and Immunology, 2019 Journal Article, 2019

A.D. Irvine, P. Mina"Osorio, Disease trajectories in childhood atopic dermatitis: an update and practitioner's guide, British Journal of Dermatology, 2019 Journal Article, 2019

Paller, A.S., Spergel, J.M., Mina-Osorio, P., Irvine, A.D., The atopic march and atopic multimorbidity: Many trajectories, many pathways, Journal of Allergy and Clinical Immunology, 143, (1), 2019, p46-55 Journal Article, 2019

Eyerich, K., Brown, S.J., Perez White, B.E., Tanaka, R.J., Bissonette, R., Dhar, S., Bieber, T., Hijnen, D.J., Guttman-Yassky, E., Irvine, A., Thyssen, J.P., Vestergaard, C., Werfel, T., Wollenberg, A., Paller, A.S., Reynolds, N.J., Human and computational models of atopic dermatitis: A review and perspectives by an expert panel of the International Eczema Council, Journal of Allergy and Clinical Immunology, 143, (1), 2019, p36-45 Journal Article, 2019

F.M. Vermeulen, L.A.A. Gerbens, A.L. Bosma, C.J. Apfelbacher, A.D. Irvine, B.W.M. Arents, S. Barbarot, M. Deleuran, L.F. Eichenfield, A. Manca, J. Schmitt, C. Vestergaard, D. Wall, S. Weidinger, M.A. Middelkamp"Hup, P.I. Spuls, C. Flohr, TRE atment of AT opic eczema ( TREAT ) Registry Taskforce: consensus on how and when to measure the core dataset for atopic eczema treatment research registries, British Journal of Dermatology, 181, (3), 2019, p492--504 Journal Article, 2019

Bosma, A.L., Spuls, P.I., Garcia-Doval, I., Naldi, L., Prieto-Merino, D., Tesch, F., Apfelbacher, C.J., Arents, B.W.M., Barbarot, S., Baselga, E., Deleuran, M., Eichenfield, L.F., Gerbens, L.A.A., Irvine, A.D., Manca, A., Mendes-Bastos, P., Middelkamp-Hup, M.A., Roberts, A., Seneschal, J., Svensson, Å., Thyssen, J.P., Torres, T., Vermeulen, F.M., Vestergaard, C., von Kobyletzki, L.B., Wall, D., Weidinger, S., Schmitt, J., Flohr, C., TREatment of ATopic eczema (TREAT) Registry Taskforce: protocol for a European safety study of dupilumab and other systemic therapies in patients with atopic eczema, British Journal of Dermatology, 2019 Journal Article, 2019

Davidson, W.F., Leung, D.Y.M., Beck, L.A., Berin, C.M., Boguniewicz, M., Busse, W.W., Chatila, T.A., Geha, R.S., Gern, J.E., Guttman-Yassky, E., Irvine, A.D., Kim, B.S., Kong, H.H., Lack, G., Nadeau, K.C., Schwaninger, J., Simpson, A., Simpson, E.L., Spergel, J.M., Togias, A., Wahn, U., Wood, R.A., Woodfolk, J.A., Ziegler, S.F., Plaut, M., Report from the National Institute of Allergy and Infectious Diseases workshop on "Atopic dermatitis and the atopic march: Mechanisms and interventions", Journal of Allergy and Clinical Immunology, 2019 Journal Article, 2019

Clowry, J., Irvine, A.D., McLoughlin, R.M., Next-generation anti"Staphylococcus aureus vaccines: A potential new therapeutic option for atopic dermatitis?, Journal of Allergy and Clinical Immunology, 143, (1), 2019, p78-81 Journal Article, 2019 TARA - Full Text DOI

Leshem, Y.A., Bissonnette, R., Paul, C., Silverberg, J.I., Irvine, A.D., Paller, A.S., Cork, M.J., Guttman-Yassky, E., Optimization of placebo use in clinical trials with systemic treatments for atopic dermatitis: an International Eczema Council survey-based position statement, Journal of the European Academy of Dermatology and Venereology, 33, (5), 2019, p807-815 Journal Article, 2019

Nicholas Stefanovic, Carsten Flohr, Alan D. Irvine, The exposome in atopic dermatitis, Allergy, 2019 Journal Article, 2019

Ballin, N., Hotz, A., Bourrat, E., Küsel, J., Oji, V., Bouadjar, B., Brognoli, D., Hickman, G., Heinz, L., Vabres, P., Marrakchi, S., Leclerc-Mercier, S., Irvine, A., Tadini, G., Hamm, H., Has, C., Blume-Peytavi, U., Mitter, D., Reitenbach, M., Hausser, I., Zimmer, A.D., Alter, S., Fischer, J., Genetical, clinical, and functional analysis of a large international cohort of patients with autosomal recessive congenital ichthyosis due to mutations in NIPAL4, Human Mutation, 40, (12), 2019, p2318-2333 Journal Article, 2019

H. Alexander, A.S. Paller, C. Traidl"Hoffmann, L.A. Beck, A. De Benedetto, S. Dhar, G. Girolomoni, A.D. Irvine, P. Spuls, J. Su, J.P. Thyssen, C. Vestergaard, T. Werfel, A. Wollenberg, M. Deleuran, C. Flohr, The role of bacterial skin infections in atopic dermatitis: expert statement and review from the International Eczema Council Skin Infection Group, British Journal of Dermatology, 2019 Journal Article, 2019

E. Chasseuil, J.A. McGrath, A. Seo, X. Balguerie, N. Bodak, H. Chasseuil, M. Denis"Musquer, A. Goldenberg, R. Goussot, A.D. Irvine, N.P. Khumalo, M.C. King, S. Küry, D. Lipsker, S. Mallet, B.M. Mayosi, A. Nanda, E. Puzenat, E. Salort"Campana, R. Sidbury, A. Shimamura, S. Bézieau, S. Mercier, S. Barbarot, Dermatological manifestations of hereditary fibrosing poikiloderma with tendon contractures, myopathy and pulmonary fibrosis ( POIKTMP ): a case series of 28 patients, British Journal of Dermatology, 2019 Journal Article, 2019

L.A.A. Gerbens, C.J. Apfelbacher, A.D. Irvine, S. Barbarot, R.J. de Booij, A.E. Boyce, M. Deleuran, L.F. Eichenfield, M.H. Hof, M.A. Middelkamp-Hup, A. Roberts, J. Schmitt, C. Vestergaard, D. Wall, S. Weidinger, P.R. Williamson, C. Flohr, P.I. Spuls, TREatment of ATopic eczema (TREAT) Registry Taskforce: an international Delphi exercise to identify a core set of domains and domain items for national atopic eczema photo- and systemic therapy registries, British Journal of Dermatology, 2018 Journal Article, 2018

Drucker, A.M., Eyerich, K., de Bruin-Weller, M.S., Thyssen, J.P., Spuls, P.I., Irvine, A.D., Girolomoni, G., Dhar, S., Flohr, C., Murrell, D.F., Paller, A.S., Guttman-Yassky, E., Use of systemic corticosteroids for atopic dermatitis: International Eczema Council consensus statement, British Journal of Dermatology, 178, (3), 2018, p768-775 Journal Article, 2018

Simpson, E.L., Reynolds, N.J., Flohr, C., Paller, A.S., Silverberg, J.I., Cork, M.J., Guttman-Yassky, E., Irvine, A.D., Response to "Comment on: `When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council"", Journal of the American Academy of Dermatology, 79, (2), 2018, pe25-e26 Journal Article, 2018

A.D. Irvine, A.P. Jones, P. Beattie, S. Baron, F. Browne, F. Ashoor, L. O'Neill, A. Rosala-Hallas, T. Sach, C. Spowart, L. Taams, C. Walker, M. Wan, N. Webb, P. Williamson, C. Flohr, A randomized controlled trial protocol assessing the effectiveness, safety and cost-effectiveness of methotrexate vs. ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema Trial (TREAT), British Journal of Dermatology, 2018 Journal Article, 2018

McCarthy, E.K., ní Chaoimh, C., Kenny, L.C., Hourihane, J.O.B., Irvine, A.D., Murray, D.M., Kiely, M.E., Iron status, body size, and growth in the first 2 years of life, Maternal and Child Nutrition, 14, (1), 2018 Journal Article, 2018

McCarthy, E.K., Murray, D.M., Malvisi, L., Kenny, L.C., O'B Hourihane, J., Irvine, A.D., Kiely, M.E., Antenatal Vitamin D Status Is Not Associated with Standard Neurodevelopmental Assessments at Age 5 Years in a Well-Characterized Prospective Maternal-Infant Cohort, Journal of Nutrition, 148, (10), 2018, p1580-1586 Journal Article, 2018

Veronika Dvorakova, David Rea, Grainne M. O'Regan, Alan D. Irvine, Generalized lymphatic anomaly successfully treated with long-term, low-dose sirolimus, Pediatric Dermatology, 2018 Journal Article, 2018

Hennessy, Á., Ní Chaoimh, C., McCarthy, E.K., Kingston, C., Irvine, A.D., Hourihane, J.O., Kenny, L.C., Murray, D.M., Kiely, M., Variation in iodine food composition data has a major impact on estimates of iodine intake in young children, European Journal of Clinical Nutrition, 72, (3), 2018, p410-419 Journal Article, 2018

M.A. McAleer, I. Jakasa, G. Hurault, P. Sarvari, W.H.I. McLean, R.J. Tanaka, S. Kezic, A.D. Irvine, Systemic and stratum corneum biomarkers of severity in infant atopic dermatitis include markers of innate and T helper cell-related immunity and angiogenesis, British Journal of Dermatology, 2018 Journal Article, 2018

Lynch, S.A., Crushell, E., Lambert, D.M., Byrne, N., Gorman, K., King, M.D., Green, A., O'Sullivan, S., Browne, F., Hughes, J., Knerr, I., Monavari, A.A., Cotter, M., McConnell, V.P.M., Kerr, B., Jones, S.A., Keenan, C., Murphy, N., Cody, D., Ennis, S., Turner, J., Irvine, A.D., Casey, J., Catalogue of inherited disorders found among the Irish Traveller population, Journal of Medical Genetics, 55, (4), 2018, p233-239 Journal Article, 2018

Twelves, S., Mostafa, A., Dand, N., Burri, E., Farkas, K., Wilson, R., Cooper, H.L., Irvine, A.D., Oon, H.H., Kingo, K., Köks, S., Mrowietz, U., Puig, L., Reynolds, N., Tan, E.S.-T., Tanew, A., Torz, K., Trattner, H., Valentine, M., Wahie, S., Warren, R.B., Wright, A., Bata-Csörg", Z., Szell, M., Griffiths, C.E.M., Burden, A.D., Choon, S.-E., Smith, C.H., Barker, J.N., Navarini, A.A., Capon, F., Clinical and genetic differences between pustular psoriasis subtypes, Journal of Allergy and Clinical Immunology, 2018 Journal Article, 2018

Paller, A.S., Czarnowicki, T., Renert-Yuval, Y., Holland, K., Huynh, T., Sadlier, M., McAleer, M.A., Tran, G., Geddes, G.C., Irvine, A.D., Guttman-Yassky, E., The spectrum of manifestations in desmoplakin gene (DSP) spectrin repeat 6 domain mutations: Immunophenotyping and response to ustekinumab, Journal of the American Academy of Dermatology, 78, (3), 2018, p498-505.e2 Journal Article, 2018

Hawkes, C.P., Murray, D.M., Kenny, L.C., Kiely, M., O'B Hourihane, J., Irvine, A.D., Wu, Z., Argon, Y., Reitz, R.E., McPhaul, M.J., Grimberg, A., Correlation of Insulin-Like Growth Factor-I and -II Concentrations at Birth Measured by Mass Spectrometry and Growth from Birth to Two Months, Hormone Research in Paediatrics, 89, (2), 2018, p122-131 Journal Article, 2018

M.A. McAleer, I. Jakasa, N. Raj, C.P.F. O'Donnell, M.E. Lane, A.V. Rawlings, R. Voegeli, W.H.I. McLean, S. Kezic, A.D. Irvine, Early-life regional and temporal variation in filaggrin-derived natural moisturizing factor, filaggrin-processing enzyme activity, corneocyte phenotypes and plasmin activity: implications for atopic dermatitis, British Journal of Dermatology, 2018 Journal Article, 2018

Hennessy, Á., Hourihane, J.O.B., Malvisi, L., Irvine, A.D., Kenny, L.C., Murray, D.M., Kiely, M.E., Antenatal vitamin D exposure and childhood eczema, food allergy, asthma and allergic rhinitis at 2 and 5 years of age in the atopic disease-specific Cork BASELINE Birth Cohort Study, Allergy: European Journal of Allergy and Clinical Immunology, 73, (11), 2018, p2182-2191 Journal Article, 2018

Pigors, M., Common, J.E.A., Wong, X.F.C.C., Malik, S., Scott, C.A., Tabarra, N., Liany, H., Liu, J., Limviphuvadh, V., Maurer-Stroh, S., Tang, M.B.Y., Lench, N., Margolis, D.J., van Heel, D.A., Mein, C.A., Novak, N., Baurecht, H., Weidinger, S., McLean, W.H.I., Irvine, A.D., O'Toole, E.A., Simpson, M.A., Kelsell, D.P., Exome Sequencing and Rare Variant Analysis Reveals Multiple Filaggrin Mutations in Bangladeshi Families with Atopic Eczema and Additional Risk Genes, Journal of Investigative Dermatology, 138, (12), 2018, p2674-2677 Journal Article, 2018

Kiely, M., O'Donovan, S.M., Kenny, L.C., Hourihane, J.O., Irvine, A.D., Murray, D.M., Vitamin D metabolite concentrations in umbilical cord blood serum and associations with clinical characteristics in a large prospective mother-infant cohort in Ireland, Journal of Steroid Biochemistry and Molecular Biology, 167, 2017, p162-168 Journal Article, 2017

Samuelov, L., Li, Q., Bochner, R., Najor, N.A., Albrecht, L., Malchin, N., Goldsmith, T., Grafi-Cohen, M., Vodo, D., Fainberg, G., Meilik, B., Goldberg, I., Warshauer, E., Rogers, T., Edie, S., Ishida-Yamamoto, A., Burzenski, L., Erez, N., Murray, S.A., Irvine, A.D., Shultz, L., Green, K.J., Uitto, J., Sprecher, E., Sarig, O., SVEP1 plays a crucial role in epidermal differentiation, Experimental Dermatology, 2017 Journal Article, 2017

Murad, A., O'Regan, G., Watson, R., McDermott, M., O'Sullivan, M., Irvine, A.D., Erythema elevatum diutinum in a healthy child, Clinical and Experimental Dermatology, 42, (4), 2017, p434-436 Journal Article, 2017

McCarthy, E.K., Kenny, L.C., Hourihane, J.O., Irvine, A.D., Murray, D.M., Kiely, M.E., Impact of maternal, antenatal and birth-associated factors on iron stores at birth: Data from a prospective maternal-infant birth cohort, European Journal of Clinical Nutrition, 71, (6), 2017, p782-787 Journal Article, 2017

Spuls, P.I., Gerbens, L.A.A., Apfelbacher, C.J., Wall, D., Arents, B.W.M., Barbarot, S., Roberts, A., Deleuran, M., Middelkamp-Hup, M.A., Vestergaard, C., Weidinger, S., Schmitt, J., Irvine, A.D., Flohr, C., The International TREatment of ATopic Eczema (TREAT) Registry Taskforce: An Initiative to Harmonize Data Collection across National Atopic Eczema Photo- and Systemic Therapy Registries, Journal of Investigative Dermatology, 137, (9), 2017, p2014-2016 Journal Article, 2017

Kennedy, E.A., Connolly, J., Hourihane, J.O., Fallon, P.G., McLean, W.H.I., Murray, D., Jo, J.-H., Segre, J.A., Kong, H.H., Irvine, A.D., Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year, Journal of Allergy and Clinical Immunology, 139, (1), 2017, p166-172 Journal Article, 2017 TARA - Full Text DOI

Gerbens, L.A.A., Boyce, A.E., Wall, D., Barbarot, S., Booij, R.J., Deleuran, M., Middelkamp-Hup, M.A., Roberts, A., Vestergaard, C., Weidinger, S., Apfelbacher, C.J., Irvine, A.D., Schmitt, J., Williamson, P.R., Spuls, P.I., Flohr, C., TREatment of ATopic eczema (TREAT) Registry Taskforce: Protocol for an international Delphi exercise to identify a core set of domains and domain items for national atopic eczema registries, Trials, 18, (1), 2017 Journal Article, 2017

Fleury, O.M., McAleer, M.A., Feuillie, C., Formosa-Dague, C., Sansevere, E., Bennett, D.E., Towell, A.M., McLean, W.H.I., Kezic, S., Robinson, D.A., Fallon, P.G., Foster, T.J., Dufrêne, Y.F., Irvine, A.D., Geoghegan, J.A., Clumping factor B promotes adherence of Staphylococcus aureus to corneocytes in atopic dermatitis, Infection and Immunity, 85, (6), 2017, ppii: e00994-16 Journal Article, 2017 TARA - Full Text

Gilhooley, E., Gormally, S., Irvine, A., Lynch, S.A., Collins, S., FOXN1 Duplication and Congenital Hypertrichosis, Pediatric Dermatology, 34, (2), 2017, pe77-e79 Journal Article, 2017

Soblet, J., Kangas, J., Nätynki, M., Mendola, A., Helaers, R., Uebelhoer, M., Kaakinen, M., Cordisco, M., Dompmartin, A., Enjolras, O., Holden, S., Irvine, A.D., Kangesu, L., Léauté-Labrèze, C., Lanoel, A., Lokmic, Z., Maas, S., McAleer, M.A., Penington, A., Rieu, P., Syed, S., van der Vleuten, C., Watson, R., Fishman, S.J., Mulliken, J.B., Eklund, L., Limaye, N., Boon, L.M., Vikkula, M., Blue Rubber Bleb Nevus (BRBN) Syndrome Is Caused by Somatic TEK (TIE2) Mutations, Journal of Investigative Dermatology, 137, (1), 2017, p207-216 Journal Article, 2017

Lovgren, M.-L., McAleer, M.A., Irvine, A.D., Wilson, N.J., Tavadia, S., Schwartz, M.E., Cole, C., Sandilands, A., Smith, F.J.D., Zamiri, M., Mutations in desmoglein 1 cause diverse inherited palmoplantar keratoderma phenotypes: implications for genetic screening, British Journal of Dermatology, 176, (5), 2017, p1345-1350 Journal Article, 2017

Simpson, E.L., Bruin-Weller, M., Flohr, C., Ardern-Jones, M.R., Barbarot, S., Deleuran, M., Bieber, T., Vestergaard, C., Brown, S.J., Cork, M.J., Drucker, A.M., Eichenfield, L.F., Foelster-Holst, R., Guttman-Yassky, E., Nosbaum, A., Reynolds, N.J., Silverberg, J.I., Schmitt, J., Seyger, M.M.B., Spuls, P.I., Stalder, J.-F., Su, J.C., Takaoka, R., Traidl-Hoffmann, C., Thyssen, J.P., van der Schaft, J., Wollenberg, A., Irvine, A.D., Paller, A.S., When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council, Journal of the American Academy of Dermatology, 77, (4), 2017, p623-633 Journal Article, 2017

Storan, E.R., Irvine, A.D., Access to Genetic Diagnostics for Genodermatoses: Who Should Get Tested? Why? Who Pays?, Pediatric Dermatology, 34, (1), 2017, p105-108 Journal Article, 2017

McCarthy, E.K., Kiely, M.E., Hannon, G., Ahearne, C., Kenny, L.C., Hourihane, J.O., Irvine, A.D., Murray, D.M., Microcytosis is associated with low cognitive outcomes in healthy 2-year-olds in a high-resource setting, British Journal of Nutrition, 118, (5), 2017, p360-367 Journal Article, 2017

Veronika Dvorakova, Grainne M. O'Regan, Alan D. Irvine, Methotrexate for Severe Childhood Atopic Dermatitis: Clinical Experience in a Tertiary Center, Pediatric Dermatology, 2017 Journal Article, 2017

Irvine, A.D., Eichenfield, L.F., Friedlander, S.F., Simpson, E.L., Review of Critical Issues in the Pathogenesis of Atopic Dermatitis, Seminars in cutaneous medicine and surgery, 35, (5), 2016, pS89-S91 Journal Article, 2016

Satveer K. Mahil, Sophie Twelves, Katalin Farkas, Niovi Setta-Kaffetzi, A. David Burden, Joanna E. Gach, Alan D. Irvine, László Képíró, Maja Mockenhaupt, Hazel H. Oon, Jason Pinner, Annamari Ranki, Marieke M.B. Seyger, Pere Soler-Palacin, Eoin R. Storan, Eugene S. Tan, Laurence Valeyrie-Allanore, Helen S. Young, Richard C. Trembath, Siew-Eng Choon, Marta Szell, Zsuzsanna Bata-Csorgo, Catherine H. Smith, Paola Di Meglio, Jonathan N. Barker, Francesca Capon, AP1S3 Mutations Cause Skin Autoinflammation by Disrupting Keratinocyte Autophagy and Up-Regulating IL-36 Production, Journal of Investigative Dermatology, 136, (11), 2016, p2251--2259 Journal Article, 2016

Eichenfield, L.F., Friedlander, S.F., Simpson, E.L., Irvine, A.D., Assessing the New and Emerging Treatments for Atopic Dermatitis, Seminars in cutaneous medicine and surgery, 35, (5), 2016, pS92-S96 Journal Article, 2016

Friedlander, S.F., Simpson, E.L., Irvine, A.D., Eichenfield, L.F., The Changing Paradigm of Atopic Dermatitis Therapy, Seminars in cutaneous medicine and surgery, 35, (5), 2016, pS97-S99 Journal Article, 2016

Kelleher MM, Dunn-Galvin A, Gray C, Murray DM, Kiely M, Kenny L, McLean WH, Irvine AD, Hourihane JO, Skin barrier impairment at birth predicts food allergy at 2 years of age., The Journal of allergy and clinical immunology, 2016 Journal Article, 2016 TARA - Full Text DOI

Chaoimh, C., Murray, D.M., Kenny, L.C., Irvine, A.D., O'Hourihane, J.B., Kiely, M., Cord blood leptin and gains in body weight and fat mass during infancy, European Journal of Endocrinology, 175, (5), 2016, p403-410 Journal Article, 2016

O'Donovan SM, O'B Hourihane J, Murray DM, Kenny LC, Khashan AS, Chaoimh CN, Irvine AD, Kiely M, Neonatal adiposity increases the risk of atopic dermatitis during the first year of life., The Journal of allergy and clinical immunology, 137, (1), 2016, p108-17 Journal Article, 2016 TARA - Full Text DOI

Schmitt J, Schwarz K, Baurecht H, Hotze M, Fölster-Holst R, Rodríguez E, Lee YA, Franke A, Degenhardt F, Lieb W, Gieger C, Kabesch M, Nöthen MM, Irvine AD, McLean WH, Deckert S, Stephan V, Schwarz P, Aringer M, Novak N, Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes., 2016 Journal Article, 2016

Ní Chaoimh, C., McCarthy, E.K., Hourihane, J.O., Kenny, L.C., Irvine, A.D., Murray, D.M., Kiely, M.E., Low vitamin D deficiency in Irish toddlers despite northerly latitude and a high prevalence of inadequate intakes, European Journal of Nutrition, 2016, p1-12 Journal Article, 2016

Mccarthy, E.K., ní Chaoimh, C., O'B Hourihane, J., Kenny, L.C., Irvine, A.D., Murray, D.M., Kiely, M., Iron intakes and status of 2-year-old children in the Cork BASELINE Birth Cohort Study, Maternal and Child Nutrition, 2016 Journal Article, 2016

Jessica Strid, W.H. Irwin McLean, Alan D. Irvine, Too Much, Too Little or Just Enough: A Goldilocks Effect for IL-13 and Skin Barrier Regulation?, Journal of Investigative Dermatology, 136, (3), 2016, p561--564 Journal Article, 2016

Bieber, T., Akdis, C., Lauener, R., Traidl-Hoffmann, C., Schmid-Grendelmeier, P., Schäppi, G., Allam, J.-P., Apfelbacher, C., Augustin, M., Beck, L., Biedermann, T., Braun-Fahrländer, C., Chew, F.T., Clavel, T., Crameri, R., Darsow, U., Deleuran, M., Dittlein, D., Duchna, H.-W., Eichenfeld, L., Eyerich, K., Frei, R., Gelmetti, C., Gieler, U., Gilles, S., Glatz, M., Grando, K., Green, J., Gutermuth, J., Guttman-Yassky, E., Hanifin, J., Hijnen, D., Hoetzenecker, W., Irvine, A., Kalweit, A., Katoh, N., Knol, E., Koren, H., Möhrenschlager, M., Münch, D., Novak, N., O'Mahony, L., Paller, A.S., Rhyner, C., Roduit, C., Schiesser, K., Schröder, J., Simon, D., Simon, H.-U., Sokolowska, M., Spuls, P., Stalder, J.-F., Straub, D., Szalai, Z., Taieb, A., Takaoka, R., Todd, G., Todorova, A., Vestergaard, C., Werfel, T., Wollenberg, A., Ring, J., Global Allergy Forum and 3rd Davos Declaration 2015: Atopic dermatitis/Eczema: Challenges and opportunities toward precision medicine, Allergy: European Journal of Allergy and Clinical Immunology, 71, (5), 2016, p588-592 Journal Article, 2016

Dvorakova V, Watson RM, Terron-Kwiatkowski A, Andrew N, Irvine AD, Congenital reticular ichthyosiform erythroderma., Clinical and experimental dermatology, 2016 Journal Article, 2016 TARA - Full Text DOI

Hawkes, C.P., Zemel, B.S., Kiely, M., Irvine, A.D., Kenny, L.C., O'B Hourihane, J., Murray, D.M., Body composition within the first 3 months: Optimized correction for length and correlation with BMI at 2 Years, Hormone Research in Paediatrics, 86, (3), 2016, p178-187 Journal Article, 2016

Simpson, E.L., Irvine, A.D., Eichenfield, L.F., Friedlander, S.F., Update on Epidemiology, Diagnosis, and Disease Course of Atopic Dermatitis, Seminars in cutaneous medicine and surgery, 35, (5), 2016, pS84-S88 Journal Article, 2016

Janna Nousbeck, Alan D. Irvine, Atopic Dermatitis According to GARP: New Mechanistic Insights in Disease Pathogenesis, Journal of Investigative Dermatology, 136, (12), 2016, p2340--2341 Journal Article, 2016

Domínguez-Hüttinger, E., Christodoulides, P., Miyauchi, K., Irvine, A.D., Okada-Hatakeyama, M., Kubo, M., Tanaka, R.J., Mathematical modeling of atopic dermatitis reveals "double-switch" mechanisms underlying 4 common disease phenotypes, Journal of Allergy and Clinical Immunology, 2016 Journal Article, 2016

Baurecht H, Hotze M, Brand S, Büning C, Cormican P, Corvin A, Ellinghaus D, Ellinghaus E, Esparza-Gordillo J, Fölster-Holst R, Franke A, Gieger C, Hubner N, Illig T, Irvine AD, Kabesch M, Lee YA, Lieb W, Marenholz I, McLean WH, Morris DW, Mrowietz U, Nair R, Nöthen MM, Novak N, O'Regan GM, Schreiber S, Smith C, Strauch K, Stuart PE, Trembath R, Tsoi LC, Weichenthal M, Barker J, Elder JT, Weidinger S, Cordell HJ, Brown SJ, Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms., American journal of human genetics, 96, (1), 2015, p104-20 Journal Article, 2015 DOI TARA - Full Text

O"Donovan, S.M., Murray, D.M., Hourihane, J.O., Kenny, L.C., Irvine, A.D., Kiely, M., Adherence with early infant feeding and complementary feeding guidelines in the Cork BASELINE Birth Cohort Study, Public Health Nutrition, 2015 Journal Article, 2015

Hussain Safia, Berki Dorottya M., Choon Siew-Eng, Burden A. David, Allen Michael H., Arostegui Juan I., Chaves Antonio, Duckworth Michael, Irvine Alan D., Mockenhaupt Maja, Navarini Alexander A., Seyger Marieke M.B., Soler-Palacin Pere, Prins Christa, Valeyrie-Allanore Laurence, Vicente M. Asuncion, Trembath Richard C., Smith Catherine H., Barker Jonathan N., Capon Francesca, IL36RN mutations define a severe autoinflammatory phenotype of generalized pustular psoriasis , Journal of Allergy and Clinical Immunology , 135 , (4 ), 2015, p1067 - 1070.e9 Journal Article, 2015 TARA - Full Text URL DOI

Oosthuizen L, Mc Aleer MA, Watson RM, O"Regan GM, Byrne A, Crispino-O"Connell G, Irvine AD, Nottingham Eczema Severity Scoring tool can identify children at high risk of food allergy to cow"s milk, egg and peanut., 2015 Journal Article, 2015

Berki DM, Liu L, Choon SE, Burden AD, Griffiths CE, Navarini AA, Tan ES, Irvine AD, Ranki A, Ogo T, Petrof G, Mahil SK, Duckworth M, Allen MH, Vito P, Trembath RC, McGrath J, Smith CH, Capon F, Barker JN, Activating CARD14 Mutations Are Associated with Generalized Pustular Psoriasis but Rarely Account for Familial Recurrence in Psoriasis Vulgaris., The Journal of investigative dermatology, 135, (12), 2015, p2964-70 Journal Article, 2015 DOI TARA - Full Text

O'Rafferty, C., O'Regan, G.M., Irvine, A.D., Smith, O.P., Recent advances in the pathobiology and management of Kasabach-Merritt phenomenon, British Journal of Haematology, 2015 Journal Article, 2015

Higgins, E., Al Shehri, T., McAleer, M.A., Conlon, N., Feighery, C., Lilic, D., Irvine, A.D., Use of ruxolitinib to successfully treat chronic mucocutaneous candidiasis caused by gain-of-function signal transducer and activator of transcription 1 (STAT1) mutation, Journal of Allergy and Clinical Immunology, 135, (2), 2015, p551-553 Journal Article, 2015

McAleer MA, Pohler E, Smith FJ, Wilson NJ, Cole C, MacGowan S, Koetsier JL, Godsel LM, Harmon RM, Gruber R, Crumrine D, Elias PM, McDermott M, Butler K, Broderick A, Sarig O, Sprecher E, Green KJ, McLean WH, Irvine AD, Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin., The Journal of allergy and clinical immunology, 2015 Journal Article, 2015 TARA - Full Text DOI

Connor S, O'Brien M, Irvine A, O'Marcaigh A, Smith O, C3-C4 shingles post haematopoietic stem-cell transplantation., 2015 Journal Article, 2015

Riethmuller C, McAleer MA, Koppes SA, Abdayem R, Franz J, Haftek M, Campbell LE, MacCallum SF, McLean WH, Irvine AD, Kezic S, Filaggrin breakdown products determine corneocyte conformation in patients with atopic dermatitis., The Journal of allergy and clinical immunology, 2015 Journal Article, 2015 TARA - Full Text DOI

O'Donovan SM, Murray DM, Hourihane JO, Kenny LC, Irvine AD, Kiely M, Cohort profile: The Cork BASELINE Birth Cohort Study: Babies after SCOPE: Evaluating the Longitudinal Impact on Neurological and Nutritional Endpoints., 2015 Journal Article, 2015

O'Rafferty, C., O'Regan, G.M., Irvine, A.D., Smith, O.P., Kasabach-Merritt syndrome, kaposiform haemangioendothelioma and platelet blockade, British Journal of Haematology, 2015 Journal Article, 2015

Wedgeworth E, Glover M, Irvine AD, Neri I, Baselga Torres E, Clayton TH, Beattie PE, Bjerre JV, Burrows NP, Foelster-Holst R, Hedelund L, Hernandez-Martin A, Audrain H, Bhate K, Brown SJ, Baryschpolec S, Darne S, Durack A, Dvorakova V, Gach J, Goldstraw N, Goodyear H, Grabcyznska S, Greenblatt D, Halpern J, Hearn RM, Hoey S, Hughes B, Jayaraj R, Johansson EK, Lam M, Leech S, O'Regan GM, Morrison D, Porter W, Ramesh R, Schill T, Shaw L, Taylor AE, Taylor R, Thomson J, Tiffin P, Tsakok M, Janmohamed SR, Laguda B, McPherson T, Oranje A, Patrizi A, Ravenscroft J, Shahidullah H, Soloman L, Svensson A, Wahlgren CF, Hoeger PH, Flohr C, Propranolol in the treatment of infantile haemangiomas: Lessons from the European Propranolol In the Treatment of Complicated Haemangiomas (PITCH) Taskforce Survey., The British journal of dermatology, 2015 Journal Article, 2015 DOI TARA - Full Text

Chen, Y.-C., Auer-Grumbach, M., Matsukawa, S., Zitzelsberger, M., Themistocleous, A.C., Strom, T.M., Samara, C., Moore, A.W., Cho, L.T.-Y., Young, G.T., Weiss, C., Schabhüttl, M., Stucka, R., Schmid, A.B., Parman, Y., Graul-Neumann, L., Heinritz, W., Passarge, E., Watson, R.M., Hertz, J.M., Moog, U., Baumgartner, M., Valente, E.M., Pereira, D., Restrepo, C.M., Katona, I., Dusl, M., Stendel, C., Wieland, T., Stafford, F., Reimann, F., Von Au, K., Finke, C., Willems, P.J., Nahorski, M.S., Shaikh, S.S., Carvalho, O.P., Nicholas, A.K., Karbani, G., McAleer, M.A., Cilio, M.R., McHugh, J.C., Murphy, S.M., Irvine, A.D., Jensen, U.B., Windhager, R., Weis, J., Bergmann, C., Rautenstrauss, B., Baets, J., De Jonghe, P., Reilly, M.M., Kropatsch, R., Kurth, I., Chrast, R., Michiue, T., Bennett, D.L.H., Woods, C.G., Senderek, J., Erratum: Transcriptional regulator PRDM12 is essential for human pain perception (Nature Genetics (2015) 47 (803-808)), Nature Genetics, 47, (8), 2015 Journal Article, 2015

Purcell, C., Cant, A., Irvine, A.D., DOCK8 primary immunodeficiency syndrome, The Lancet, 2015 Journal Article, 2015

Saunders SP, Moran T, Floudas A, Wurlod F, Kaszlikowska A, Salimi M, Quinn EM, Oliphant CJ, Núñez G, McManus R, Hams E, Irvine AD, McKenzie AN, Ogg GS, Fallon PG, Spontaneous atopic dermatitis is mediated by innate immunity, with the secondary lung inflammation of the atopic march requiring adaptive immunity., The Journal of allergy and clinical immunology, 2015 Journal Article, 2015 TARA - Full Text DOI

Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, Strachan DP, Curtin JA, Bønnelykke K, Tian C, Takahashi A, Esparza-Gordillo J, Alves AC, Thyssen JP, den Dekker HT, Ferreira MA, Altmaier E, Sleiman PM, Xiao FL, Gonzalez JR, Marenholz I, Kalb B, Pino-Yanes M, Xu CJ, Carstensen L, Groen-Blokhuis MM, Venturini C, Pennell CE, Barton SJ, Levin AM, Curjuric I, Bustamante M, Kreiner-Møller E, Lockett GA, Bacelis J, Bunyavanich S, Myers RA, Matanovic A, Kumar A, Tung JY, Hirota T, Kubo M, McArdle WL, Henderson AJ, Kemp JP, Zheng J, Smith GD, Rüschendorf F, Bauerfeind A, Lee-Kirsch MA, Arnold A, Homuth G, Schmidt CO, Mangold E, Cichon S, Keil T, Rodríguez E, Peters A, Franke A, Lieb W, Novak N, Fölster-Holst R, Horikoshi M, Pekkanen J, Sebert S, Husemoen LL, Grarup N, de Jongste JC, Rivadeneira F, Hofman A, Jaddoe VW, Pasmans SG, Elbert NJ, Uitterlinden AG, Marks GB, Thompson PJ, Matheson MC, Robertson CF, Ried JS, Li J, Zuo XB, Zheng XD, Yin XY, Sun LD, McAleer MA, O'Regan GM, Fahy CM, Campbell L, Macek M, Kurek M, Hu D, Eng C, Postma DS, Feenstra B, Geller F, Hottenga JJ, Middeldorp CM, Hysi P, Bataille V, Spector T, Tiesler CM, Thiering E, Pahukasahasram B, Yang JJ, Imboden M, Huntsman S, Vilor-Tejedor N, Relton CL, Myhre R, Nystad W, Custovic A, Weiss ST, Meyers DA, Söderhäll C, Melén E, Ober C, Raby BA, Simpson A, Jacobsson B, Holloway JW, Bisgaard H, Sunyer J, Probst-Hensch NM, Williams LK, Godfrey KM, Wang CA, Boomsma DI, Melbye M, Koppelman GH, Jarvis D, McLean WH, Irvine AD, Zhang XJ, Hakonarson H, Gieger C, Burchard EG, Martin NG, Duijts L, Linneberg A, Jarvelin MR, Nöthen MM, Lau S, Hübner N, Lee YA, Tamari M, Hinds DA, Glass D, Brown SJ, Heinrich J, Evans DM, Weidinger S, Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis., Nature genetics, 47, (12), 2015, p1449-56 Journal Article, 2015 TARA - Full Text DOI

Kelleher M, Dunn-Galvin A, Hourihane JO, Murray D, Campbell LE, McLean WH, Irvine AD, Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year., The Journal of allergy and clinical immunology, 135, (4), 2015, p930-5.e1 Journal Article, 2015 DOI TARA - Full Text

Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, Young GT, Weiss C, Schabhüttl M, Stucka R, Schmid AB, Parman Y, Graul-Neumann L, Heinritz W, Passarge E, Watson RM, Hertz JM, Moog U, Baumgartner M, Valente EM, Pereira D, Restrepo CM, Katona I, Dusl M, Stendel C, Wieland T, Stafford F, Reimann F, von Au K, Finke C, Willems PJ, Nahorski MS, Shaikh SS, Carvalho OP, Nicholas AK, Karbani G, McAleer MA, Cilio MR, McHugh JC, Murphy SM, Irvine AD, Jensen UB, Windhager R, Weis J, Bergmann C, Rautenstrauss B, Baets J, De Jonghe P, Reilly MM, Kropatsch R, Kurth I, Chrast R, Michiue T, Bennett DL, Woods CG, Senderek J, Transcriptional regulator PRDM12 is essential for human pain perception., Nature genetics, 47, (7), 2015, p803-8 Journal Article, 2015 TARA - Full Text DOI

Quinn, N., Macmahon, J., Irvine, A.D., Lowry, C., Sweet syndrome revealing Systemic Lupus Erythematosus, Irish Medical Journal, 108, (2), 2015 Journal Article, 2015

Mercier S, Küry S, Salort-Campana E, Magot A, Agbim U, Besnard T, Bodak N, Bou-Hanna C, Bréhéret F, Brunelle P, Caillon F, Chabrol B, Cormier-Daire V, David A, Eymard B, Faivre L, Figarella-Branger D, Fleurence E, Ganapathi M, Gherardi R, Goldenberg A, Hamel A, Igual J, Irvine AD, Israël-Biet D, Kannengiesser C, Laboisse C, Le Caignec C, Mahé JY, Mallet S, MacGowan S, McAleer MA, McLean I, Méni C, Munnich A, Mussini JM, Nagy PL, Odel J, O'Regan GM, Péréon Y, Perrier J, Piard J, Puzenat E, Sampson JB, Smith F, Soufir N, Tanji K, Thauvin C, Ulane C, Watson RM, Khumalo NP, Mayosi BM, Barbarot S, Bézieau S, Expanding the clinical spectrum of hereditary fibrosing poikiloderma with tendon contractures, myopathy and pulmonary fibrosis due to FAM111B mutations., Orphanet journal of rare diseases, 10, 2015, p135 Journal Article, 2015 DOI TARA - Full Text

Hussain, S., Berki, D.M., Choon, S.-E., Burden, A.D., Allen, M.H., Arostegui, J.I., Chaves, A., Duckworth, M., Irvine, A.D., Mockenhaupt, M., Navarini, A.A., Seyger, M.M.B., Soler-Palacin, P., Prins, C., Valeyrie-Allanore, L., Vicente, M.A., Trembath, R.C., Smith, C.H., Barker, J.N., Capon, F., IL36RN mutations define a severe autoinflammatory phenotype of generalized pustular psoriasis: To the editor, Journal of Allergy and Clinical Immunology, 135, (4), 2015, p1067-1070.e9 Journal Article, 2015

O"Donovan SM, Murray DM, Hourihane JO, Kenny LC, Irvine AD, Kiely M, No association between food allergens in the complementary feeding diet and eczema during the first 12-months in the Cork BASELINE Birth Cohort., 2015 Journal Article, 2015

Kiely C, Devaney D, Fischer J, Lenane P, Irvine AD, Ichthyosis prematurity syndrome: a case report and review of known mutations., Pediatric dermatology, 31, (4), 2014, p517-8 Journal Article, 2014 DOI TARA - Full Text

Nason GJ, Baker JF, Seoighe D, Irvine AD, McDermott M, Orr D, Capra M, Kelly PM, Congenital-infantile fibrosarcoma of the foot--avoidance of amputation., Irish medical journal, 107, (5), 2014, p148-9 Journal Article, 2014 URL

Thawer-Esmail F, Jakasa I, Todd G, Wen Y, Brown SJ, Kroboth K, Campbell LE, O'Regan GM, McLean WH, Irvine AD, Kezic S, Sandilands A, South African amaXhosa patients with atopic dermatitis have decreased levels of filaggrin breakdown products but no loss-of-function mutations in filaggrin., The Journal of allergy and clinical immunology, 133, (1), 2014, p280-282.e2 Journal Article, 2014 DOI TARA - Full Text

Foley C, Moran B, McMenamin M, McDermott R, Ormond P, Irvine AD, Spontaneous regression of cutaneous metastases of squamous cell carcinoma., QJM : monthly journal of the Association of Physicians, 107, (1), 2014, p61-3 Journal Article, 2014 DOI TARA - Full Text

Cole C, Kroboth K, Schurch NJ, Sandilands A, Sherstnev A, O'Regan GM, Watson RM, Irwin McLean WH, Barton GJ, Irvine AD, Brown SJ, Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis., The Journal of allergy and clinical immunology, 134, (1), 2014, p82-91 Journal Article, 2014 DOI TARA - Full Text

Courtney, D.G., Atkinson, S.D., Allen, E.H.A., Moore, J.E., Walsh, C.P., Pedrioli, D.M.L., MacEwen, C.J., Pellegrini, G., Maurizi, E., Serafini, C., Fantacci, M., Liao, H., Irvine, A.D., McIrwin Lean, W.H., Tara Moore, C.B., SiRNA silencing of the mutant keratin 12 allele in corneal limbal epithelial cells grown from patients with Meesmann's epithelial corneal dystrophy, Investigative Ophthalmology and Visual Science, 55, (5), 2014, p3352-3360 Journal Article, 2014

Hughes, R., McAleer, M., Watson, R., Collins, S., Irvine, A., White, M., Rapidly involuting congenital hemangioma with pustules: Two cases, Pediatric Dermatology, 31, (3), 2014, p398-400 Journal Article, 2014

Irvine AD, Crossing barriers; restoring barriers? Filaggrin protein replacement takes a bow., The Journal of investigative dermatology, 134, (2), 2014, p313-4 Journal Article, 2014 DOI TARA - Full Text

Irvine AD, Commentary: Methotrexate and ciclosporin in the treatment of severe eczema in children., The British journal of dermatology, 170, (3), 2014, p499-500 Journal Article, 2014 DOI TARA - Full Text

Kelleher M, Dunn AG, Irvine A, Smith H, Hourihane OJ, O08 - Increased early life Transepidermal Water Loss (TEWL) values can predate atopic dermatitis in asymptomatic infants: results from the BASELINE study., 2014 Journal Article, 2014

Gallagher, A., Hourihane, J.O.B., Kenny, L.C., Irvine, A.D., Khashan, A.S., A longitudinal study of skin barrier function in pregnancy and the postnatal period, Obstetric Medicine, 7, (4), 2014, p156-159 Journal Article, 2014

Courtney DG, Atkinson SD, Allen EH, Moore JE, Walsh CP, Pedrioli DM, MacEwen CJ, Pellegrini G, Maurizi E, Serafini C, Fantacci M, Liao H, Irvine AD, McLean WH, Moore CB, siRNA silencing of the mutant keratin 12 allele in corneal limbal epithelial cells grown from patients with Meesmann's epithelial corneal dystrophy., Investigative ophthalmology & visual science, 55, (5), 2014, p3352-60 Journal Article, 2014 DOI TARA - Full Text

Salinas, C.F., Irvine, A.D., Itin, P.H., Di Giovanna, J.J., Schneider, H., Clarke, A.J., McGovern, L.S., Fete, M., Second international conference on a classification of ectodermal dysplasias: Development of a multiaxis model, American Journal of Medical Genetics, Part A, 164, (10), 2014, p2482-2489 Journal Article, 2014

Samuelov L, Sarig O, Harmon RM, Rapaport D, Ishida-Yamamoto A, Isakov O, Koetsier JL, Gat A, Goldberg I, Bergman R, Spiegel R, Eytan O, Geller S, Peleg S, Shomron N, Goh CS, Wilson NJ, Smith FJ, Pohler E, Simpson MA, McLean WH, Irvine AD, Horowitz M, McGrath JA, Green KJ, Sprecher E, Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting., Nature genetics, 45, (10), 2013, p1244-8 Journal Article, 2013 DOI TARA - Full Text

McAleer MA, Irvine AD, The multifunctional role of filaggrin in allergic skin disease., The Journal of allergy and clinical immunology, 131, (2), 2013, p280-91 Journal Article, 2013 TARA - Full Text DOI

Flohr C, Irvine AD, Systemic therapies for severe atopic dermatitis in children and adults., The Journal of allergy and clinical immunology, 132, (3), 2013, p774-774.e6 Journal Article, 2013 DOI TARA - Full Text

Fahy CM, Fortune A, Quinn F, McMenamin ME, Browne PV, Langabeer S, McCarron S, Hayden P, Marren P, Ni Chonghaile M, Irvine AD, Vandenberghe E, Barnes L, Development of mycosis fungoides after bone marrow transplantation for chronic myeloid leukaemia; transmission from allogeneic donor., The British journal of dermatology, 2013 Journal Article, 2013

Baclig, A.C., Bakker Schut, T.C., O'Regan, G.M., Irvine, A.D., McLean, W.H.I., Puppels, G.J., Caspers, P.J., Possibilities for human skin characterization based on strongly reduced Raman spectroscopic information, Journal of Raman Spectroscopy, 44, (3), 2013, p340-345 Journal Article, 2013

Kelleher MM, O'Carroll M, Gallagher A, Murray DM, Dunn Galvin A, Irvine AD, Hourihane JO, Newborn transepidermal water loss values: a reference dataset., Pediatric dermatology, 30, (6), 2013, p712-6 Journal Article, 2013

Foley CC, McMenamin M, Gordon KD, Irvine AD, An unusual case of genital swelling., Clinical and experimental dermatology, 38, (8), 2013, p946-8 Journal Article, 2013

Langan SM, Irvine AD, Childhood eczema and the importance of the physical environment., The Journal of investigative dermatology, 133, (7), 2013, p1706-9 Journal Article, 2013 TARA - Full Text DOI

Wall D, McMenamin M, O'Mahony D, Irvine AD, Kaposi sarcoma in an patient with atopic dermatitis treated with ciclosporin., BMJ case reports, 2013, 2013 Journal Article, 2013 TARA - Full Text DOI

Weidinger S, Willis-Owen SA, Kamatani Y, Baurecht H, Morar N, Liang L, Edser P, Street T, Rodriguez E, O'Regan GM, Beattie P, Fölster-Holst R, Franke A, Novak N, Fahy CM, Winge MC, Kabesch M, Illig T, Heath S, Söderhäll C, Melén E, Pershagen G, Kere J, Bradley M, Lieden A, Nordenskjold M, Harper JI, McLean WH, Brown SJ, Cookson WO, Lathrop GM, Irvine AD, Moffatt MF, A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis., Human molecular genetics, 22, (23), 2013, p4841-56 Journal Article, 2013 TARA - Full Text DOI

Revencu N, Boon LM, Mendola A, Cordisco MR, Dubois J, Clapuyt P, Hammer F, Amor DJ, Irvine AD, Baselga E, Dompmartin A, Syed S, Martin-Santiago A, Ades L, Collins F, Smith J, Sandaradura S, Barrio VR, Burrows PE, Blei F, Cozzolino M, Brunetti-Pierri N, Vicente A, Abramowicz M, Désir J, Vilain C, Chung WK, Wilson A, Gardiner CA, Dwight Y, Lord DJ, Fishman L, Cytrynbaum C, Chamlin S, Ghali F, Gilaberte Y, Joss S, Boente Mdel C, Léauté-Labrèze C, Delrue MA, Bayliss S, Martorell L, González-Enseñat MA, Mazereeuw-Hautier J, O'Donnell B, Bessis D, Pyeritz RE, Salhi A, Tan OT, Wargon O, Mulliken JB, Vikkula M, RASA1 mutations and associated phenotypes in 68 families with capillary malformation-arteriovenous malformation., Human mutation, 34, (12), 2013, p1632-41 Journal Article, 2013

McLean WH, Irvine AD, Old King Coal - molecular mechanisms underlying an ancient treatment for atopic eczema., The Journal of clinical investigation, 2013, p1-3 Journal Article, 2013 TARA - Full Text DOI

Ellinghaus D, Baurecht H, Esparza-Gordillo J, Rodríguez E, Matanovic A, Marenholz I, Hübner N, Schaarschmidt H, Novak N, Michel S, Maintz L, Werfel T, Meyer-Hoffert U, Hotze M, Prokisch H, Heim K, Herder C, Hirota T, Tamari M, Kubo M, Takahashi A, Nakamura Y, Tsoi LC, Stuart P, Elder JT, Sun L, Zuo X, Yang S, Zhang X, Hoffmann P, Nöthen MM, Fölster-Holst R, Winkelmann J, Illig T, Boehm BO, Duerr RH, Büning C, Brand S, Glas J, McAleer MA, Fahy CM, Kabesch M, Brown S, McLean WH, Irvine AD, Schreiber S, Lee YA, Franke A, Weidinger S, High-density genotyping study identifies four new susceptibility loci for atopic dermatitis., Nature genetics, 45, (7), 2013, p808-12 Journal Article, 2013 DOI TARA - Full Text

Higgins E, Capra M, Schwartz ME, Smith FJD, McLean WHI, Irvine AD, Resolution of the plantar hyperkeratosis of pachyonychia congenita during chemotherapy for Ewing sarcoma , British Journal of Dermatology , 169 , (6 ), 2013, p1357 - 1360 Journal Article, 2013 TARA - Full Text

Asai, Yuka Greenwood, Celia Hull, Peter R. Alizadehfar, Reza Ben-Shoshan, Moshe Brown, Sara J. Campbell, Linda Michel, Deborah L. Bussières, Johanne Rousseau, François Fujiwara, T. Mary Morgan, Kenneth Irvine, Alan D. McLean, W.H. Irwin Clarke, Ann , Filaggrin gene mutation associations with peanut allergy persist despite variations in peanut allergy diagnostic criteria or asthma status , Journal of Allergy and Clinical Immunology , 132 , (1 ), 2013, p239 - 242.e7 Journal Article, 2013 TARA - Full Text URL DOI

Conte MI, Pescatore A, Paciolla M, Esposito E, Miano MG, Lioi MB, McAleer MA, Giardino G, Pignata C, Irvine AD, Scheuerle AE, Royer G, Hadj-Rabia S, Bodemer C, Bonnefont JP, Munnich A, Smahi A, Steffann J, Fusco F, Ursini MV, Insight into IKBKG/NEMO Locus: Report of New Mutations and Complex Genomic Rearrangements Leading to Incontinentia Pigmenti Disease., Human mutation, 2013 Journal Article, 2013

Saunders, S.P., Goh, C.S.M., Brown, S.J., Palmer, C.N.A., Porter, R.M., Cole, C., Campbell, L.E., Gierlinski, M., Barton, G.J., Schneider, G., Balmain, A., Prescott, A.R., Weidinger, S., Baurecht, H., Kabesch, M., Gieger, C., Lee, Y.-A., Tavendale, R., Mukhopadhyay, S., Turner, S.W., Madhok, V.B., Sullivan, F.M., Relton, C., Burn, J., Meggitt, S., Smith, C.H., Allen, M.A., Barker, J.N.W.N., Reynolds, N.J., Cordell, H.J., Irvine, A.D., McLean, W.H.I., Sandilands, A., Fallon, P.G., Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects, Journal of Allergy and Clinical Immunology, 132, (5), 2013, p1121-1129 Journal Article, 2013 DOI TARA - Full Text

Hackett BC, Phelan E, Ryan A, Kenny L, Murphy M, Irvine AD, Watson RM, Use of Systemic Corticosteroids in Management of a Large Congenital Haemangioma of the Scalp., Pediatric dermatology, 2012 Journal Article, 2012

Pohler E, Mamai O, Hirst J, Zamiri M, Horn H, Nomura T, Irvine AD, Moran B, Wilson NJ, Smith FJ, Goh CS, Sandilands A, Cole C, Barton GJ, Evans AT, Shimizu H, Akiyama M, Suehiro M, Konohana I, Shboul M, Teissier S, Boussofara L, Denguezli M, Saad A, Gribaa M, Dopping-Hepenstal PJ, McGrath JA, Brown SJ, Goudie DR, Reversade B, Munro CS, McLean WH, Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma., Nature genetics, 44, (11), 2012, p1272-6 Journal Article, 2012 TARA - Full Text DOI

Tsoi LC, Spain SL, Knight J, Ellinghaus E, Stuart PE, Capon F, Ding J, Li Y, Tejasvi T, Gudjonsson JE, Kang HM, Allen MH, McManus R, Novelli G, Samuelsson L, Schalkwijk J, Ståhle M, Burden AD, Smith CH, Cork MJ, Estivill X, Bowcock AM, Krueger GG, Weger W, Worthington J, Tazi-Ahnini R, Nestle FO, Hayday A, Hoffmann P, Winkelmann J, Wijmenga C, Langford C, Edkins S, Andrews R, Blackburn H, Strange A, Band G, Pearson RD, Vukcevic D, Spencer CC, Deloukas P, Mrowietz U, Schreiber S, Weidinger S, Koks S, Kingo K, Esko T, Metspalu A, Lim HW, Voorhees JJ, Weichenthal M, Wichmann HE, Chandran V, Rosen CF, Rahman P, Gladman DD, Griffiths CE, Reis A, Kere J, Nair RP, Franke A, Barker JN, Abecasis GR, Elder JT, Trembath RC, Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity., Nature genetics, 44, (12), 2012, p1341-1348 Journal Article, 2012 DOI

Kezic S, O'Regan GM, Lutter R, Jakasa I, Koster ES, Saunders S, Caspers P, Kemperman PM, Puppels GJ, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Fallon PG, McLean WH, Irvine AD, Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency., The Journal of allergy and clinical immunology, 129, (4), 2012, p1031-9.e1 Journal Article, 2012 TARA - Full Text DOI

McLean WH, Irvine AD, Heritable filaggrin disorders: the paradigm of atopic dermatitis., The Journal of investigative dermatology, 132, (E1), 2012, pE20-1 Journal Article, 2012 DOI TARA - Full Text

McAleer MA, Flohr C, Irvine AD, Management of difficult and severe eczema in childhood., BMJ (Clinical research ed.), 345, 2012, pe4770 Journal Article, 2012 TARA - Full Text

Irvine AD, Double trouble: homozygous dominant mutations and hair loss in pachyonychia congenita., The Journal of investigative dermatology, 132, (7), 2012, p1757-9 Journal Article, 2012 DOI TARA - Full Text

Brown SJ, Kroboth K, Sandilands A, Campbell LE, Pohler E, Kezic S, Cordell HJ, McLean WH, Irvine AD, Intragenic copy number variation within filaggrin contributes to the risk of atopic dermatitis with a dose-dependent effect., The Journal of investigative dermatology, 132, (1), 2012, p98-104 Journal Article, 2012

Crushell E, O'Leary D, Irvine AD, O'Shea A, Mayne PD, Reardon W, Methylenetetrahydrofolate reductase (MTHFR) deficiency presenting as a rash., American journal of medical genetics. Part A, 158A, (9), 2012, p2254-7 Journal Article, 2012 DOI

Krawczyk J, McDermott M, Irvine AD, O'Marcaigh A, Storey L, Smith O, Skin involvement in Down syndrome transient abnormal myelopoiesis., British journal of haematology, 157, (3), 2012, p280 Journal Article, 2012

Porokeratoses in, editor(s)Goldsmith LA, Katz SI, Gilchrest BA, Paller A, Leffell DJ , Fitzpatrick's Dermatology in General Medicine , New York , McGraw Hill, 2012, ppxxx - xxx, [O'Regan GM, Irvine AD] Book Chapter, 2012

Knight J, Spain SL, Capon F, Hayday A, Nestle FO, Clop A, Wellcome Trust Case Control Consortium, Genetic Analysis of Psoriasis Consortium§, I-chip for Psoriasis Consortium, Barker JN. Weale ME, Trembath RC, Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis, Human Molecular Genetics, 21, (23), 2012, p5185 - 5192 Journal Article, 2012 TARA - Full Text DOI

Sandilands Aileen, Brown Sara J, Goh Christabelle S, Pohler Elizabeth, Wilson Neil J, Campbell Linda E, Miyamoto Kenichi, Kubo Akiharu, Irvine Alan D, Thawer-Esmail Fatema, Mutations in the SASPase gene (ASPRV1) are not associated with atopic eczema or clinically dry skin , The Journal of investigative dermatology , 132 , (5 ), 2012, p1507 - Journal Article, 2012 TARA - Full Text

Miajlovic H, Fallon PG, Irvine AD, Foster TJ., Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus, Journal of Allergy and Clinical Immunology, 126, (6), 2011, p1184-1190 Journal Article, 2011 DOI TARA - Full Text

Irvine, A.D., Hoeger, P.H., Yan, A.C., Preface to the third edition, Harper's Textbook of Pediatric Dermatology: Third Edition, 1, 2011 Journal Article, 2011

Bracken J, Robinson I, Snow A, Watson R, Irvine AD, Rea D, Phelan E, PHACE syndrome: MRI of intracerebral vascular anomalies and clinical findings in a series of 12 patients., Pediatric radiology, 41, (9), 2011, p1129-38 Journal Article, 2011

Atopic Dermatitis: Genetics in, editor(s)Irvine AD, Hoeger PH, Yan A , Textbook of Pediatric Dermatology , London , Blackwell-Wiley, 2011, pp1 - 23, [Weidinger S, Irvine AD ] Book Chapter, 2011

Liao H, Irvine AD, Macewen CJ, Weed KH, Porter L, Corden LD, Gibson AB, Moore JE, Smith FJ, McLean WH, Moore CB, Development of Allele-Specific Therapeutic siRNA in Meesmann Epithelial Corneal Dystrophy., PloS one, 6, (12, e28582), 2011 Journal Article, 2011 DOI TARA - Full Text

Chen H, Common JE, Haines RL, Balakrishnan A, Brown SJ, Goh CS, Cordell HJ, Sandilands A, Campbell LE, Kroboth K, Irvine AD, Goh DL, Tang MB, van Bever HP, Giam YC, McLean WH, Lane EB, Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations., The British journal of dermatology, 165, (1), 2011, p106-14 Journal Article, 2011

Fleming P, Fitzgerald K, Watson R, Irvine A. , Response to "dental caries as a side effect of infantile hemangioma treatment with propanolol solution", Pediatric Dermatology, 28, 2011, p602 - 602 Journal Article, 2011

Pediatric Dermatology in, editor(s)Irvine AD, Hoeger PH, Yan A , Harper's Textbook of Pediatric Dermatology , London, Blackwell-Wiley, 2011, pp2816 - [Weidinger S, Irvine AD] Book Chapter, 2011

Keohane, C., Bacon, C.L., Moran, B., Irvine, A.D., Smith, O.P., Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome induced by cidofovir, Pediatric Transplantation, 15, (1), 2011 Journal Article, 2011

Ricciardo B, Irvine A, McDermott M, Ryan J, Collins S, A case of congenital solitary Langerhans cell histiocytoma., The Australasian journal of dermatology, 52, (2), 2011, pe1-3 Journal Article, 2011

Kezic S, O'Regan GM, Yau N, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Rowland M, McLean WH, Irvine AD, Levels of filaggrin degradation products are influenced by both filaggrin genotype and atopic dermatitis severity., Allergy, 66, (7), 2011, p934-40 Journal Article, 2011 DOI TARA - Full Text

Ectodermal Dysplasias in, editor(s)Irvine AD, Hoeger PH, Yan A , Textbook of Pediatric Dermatology, London, Blackwell‐Wiley, 2011, pp1 - 127, [Asai Y, Irvine AD ] Book Chapter, 2011

Irvine AD, McLean WH, Leung DY, Filaggrin mutations associated with skin and allergic diseases., The New England journal of medicine, 365, (14), 2011, p1315-27 Journal Article, 2011

Brown SJ, Asai Y, Cordell HJ, Campbell LE, Zhao Y, Liao H, Northstone K, Henderson J, Alizadehfar R, Ben-Shoshan M, Morgan K, Roberts G, Masthoff LJ, Pasmans SG, van den Akker PC, Wijmenga C, Hourihane JO, Palmer CN, Lack G, Clarke A, Hull PR, Irvine AD, McLean WH, Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy., The Journal of allergy and clinical immunology, 127, (3), 2011, p661-7 Journal Article, 2011 DOI TARA - Full Text

Scurr I, Wilson L, Lees M, Robertson S, Kirk E, Turner A, Morton J, Kidd A, Shashi V, Stanley C, Berry M, Irvine AD, Goudie D, Turner C, Brewer C, Smithson S, Cantú syndrome: report of nine new cases and expansion of the clinical phenotype., American journal of medical genetics. Part A, 155A, (3), 2011, p508-18 Journal Article, 2011

Clericuzio C, Harutyunyan K, Jin W, Erickson RP, Irvine AD, McLean WH, Wen Y, Bagatell R, Griffin TA, Shwayder TA, Plon SE, Wang LL, Identification of a novel C16orf57 mutation in Athabaskan patients with Poikiloderma with Neutropenia., American journal of medical genetics. Part A, 155A, (2), 2011, p337-42 Journal Article, 2011 TARA - Full Text DOI

Weidinger, S., Irvine, A.D., Genetics of Atopic Dermatitis, Harper's Textbook of Pediatric Dermatology: Third Edition, 1, 2011, p1-17 Journal Article, 2011

Hawkes CP, Hourihane JO, Kenny LC, Irvine AD, Kiely M, Murray DM, Gender- and gestational age-specific body fat percentage at birth., Pediatrics, 128, (3), 2011, pe645-51 Journal Article, 2011 DOI TARA - Full Text

Irvine, A.D., Hoeger, P.H., Yan, A.C., Harper's Textbook of Pediatric Dermatology: Third Edition, Harper's Textbook of Pediatric Dermatology: Third Edition, 1-2, 2011 Journal Article, 2011

Other Syndromes associated with Ichthyosis in, editor(s)Schnacher L and Hansen R , Pediatric Dermatology , London, Mosby, 2010, pp612 - 614, [Irvine AD] Book Chapter, 2010

O'Regan GM, Irvine AD, The role of filaggrin in the atopic diathesis., Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 40, (7), 2010, p965-72 Journal Article, 2010

Peeling Skin Syndrome in, editor(s)Schnacher L and Hansen R , Pediatric Dermatology, London, Mosby, 2010, pp1 - 23, [Irvine AD] Book Chapter, 2010

Hackett BC, Fitzgerald D, Watson RM, Hol F.A, Irvine AD, Genotype-Phenotype Correlations with TGM1: Clustering of Mutations in the Bathing Suit Ichthyosis and Self Healing Collodion Baby Variants of Lamellar Ichthyosis, British Journal of Dermatology, 162, (2), 2010, p448-451 Journal Article, 2010 DOI

Ichthyosis Vulgaris in, editor(s)Schnacher L and Hansen R , Pediatric Dermatology, London, Mosby, 2010, pp578 - 580, [Irvine AD ] Book Chapter, 2010

O'Regan GM, Kemperman PMJH, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Rowland M, Puppels GJ, McLean WHI, Caspers PJ Irvine AD, Raman Profiles of the Stratum Corneum Define Three FLG Genotype-determined Atopic Dermatitis Endophenotypes , Journal of Allergy and Clinical Immunology, 126, 2010, p574-580 Journal Article, 2010 DOI

O'Regan GM, Campbell LE, Cordell HJ, Irvine AD, McLean WHI, Brown SJ, Chromosome 11q13.5 variant associated with childhood eczema; an effect supplementary to filaggrin mutations, Journal of Allergy and Clinical Immunology, 125, 2010, p170-174 Journal Article, 2010 DOI

Bergboer JG, Zeeuwen PL, Irvine AD, Weidinger S, Giardina E, Novelli G, Heijer MD, Rodriguez E, Illig T, Riveira-Munoz E, Campbell LE, Tyson J, Dannhauser EN, O'Regan GM, Galli E, Klopp N, Koppelman GH, Novak N, Estivill X, McLean WH, Postma DS, Armour JA, Schalkwijk J, Deletion of Late Cornified Envelope 3B and 3C Genes Is Not Associated with Atopic Dermatitis, Journal of Investigative Dermatology, 130, 2010, p2057-2061 Journal Article, 2010 DOI

Moriarty B, Bourke JF, Fitzgibbon J, Irvine AD, An unusual rash in a neonate. X-linked dominant ichthyosis (XLDI)., Clinical and experimental dermatology, 35, (3), 2010, pe62-4 Journal Article, 2010

Moriarty, B., Bourke, J.F., Fitzgibbon, J., Irvine, A.D., An unusual rash in a neonate, Clinical and Experimental Dermatology, 35, (3), 2010 Journal Article, 2010

O'Regan GM, Campbell LE, Cordell HJ, Irvine AD, McLean WH, Brown SJ, Chromosome 11q13.5 variant associated with childhood eczema: an effect supplementary to filaggrin mutations., The Journal of allergy and clinical immunology, 125, (1), 2010, p170-4.e1-2 Journal Article, 2010

Strange A, Capon F, Spencer CC, Knight J, Weale ME, Allen MH, Barton A, Band G, Bellenguez C, Bergboer JG, Blackwell JM, Bramon E, Bumpstead SJ, Casas JP, Cork MJ, Corvin A, Deloukas P, Dilthey A, Duncanson A, Edkins S, Estivill X, Fitzgerald O, Freeman C, Giardina E, Gray E, Hofer A, Hüffmeier U, Hunt SE, Irvine AD, Jankowski J, Kirby B, Langford C, Lascorz J, Leman J, Leslie S, Mallbris L, Markus HS, Mathew CG, McLean WH, McManus R, Mössner R, Moutsianas L, Naluai AT, Nestle FO, Novelli G, Onoufriadis A, Palmer CN, Perricone C, Pirinen M, Plomin R, Potter SC, Pujol RM, Rautanen A, Riveira-Munoz E, Ryan AW, Salmhofer W, Samuelsson L, Sawcer SJ, Schalkwijk J, Smith CH, Ståhle M, Su Z, Tazi-Ahnini R, Traupe H, Viswanathan AC, Warren RB, Weger W, Wolk K, Wood N, Worthington J, Young HS, Zeeuwen PL, Hayday A, Burden AD, Griffiths CE, Kere J, Reis A, McVean G, Evans DM, Brown MA, Barker JN, Peltonen L, Donnelly P, Trembath RC, A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1., Nature genetics, 42, (11), 2010, p985-990 Journal Article, 2010 DOI

O'Regan GM, Kemperman PM, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Rowland M, Puppels GJ, McLean WH, Caspers PJ, Irvine AD, Raman profiles of the stratum corneum define 3 filaggrin genotype-determined atopic dermatitis endophenotypes., The Journal of allergy and clinical immunology, 126, (3), 2010, p574-80.e1 Journal Article, 2010

Genetics and Genodermatoses in, editor(s)Burns T, Breathnach S, Cox N, Griffiths C , Rook's Textbook of Dermatology, Chichester , Wiley Blackwell, 2010, pp1 - 15.97, [Mellerio JE and Irvine AD] Book Chapter, 2010

Bergboer JG, Zeeuwen PL, Irvine AD, Weidinger S, Giardina E, Novelli G, Den Heijer M, Rodriguez E, Illig T, Riveira-Munoz E, Campbell LE, Tyson J, Dannhauser EN, O'Regan GM, Galli E, Klopp N, Koppelman GH, Novak N, Estivill X, McLean WH, Postma DS, Armour JA, Schalkwijk J, Deletion of Late Cornified Envelope 3B and 3C genes is not associated with atopic dermatitis., The Journal of investigative dermatology, 130, (8), 2010, p2057-61 Journal Article, 2010

Rodriguez S, Hall AJ, Granell R, McLean WH, Irvine AD, Palmer CN, Smith GD, Henderson J, Day IN, Carrier status for the common R501X and 2282del4 filaggrin mutations is not associated with hearing phenotypes in 5,377 children from the ALSPAC cohort, PLoS ONE, 4, (6), 2009, pe5784 Journal Article, 2009 TARA - Full Text

Sandilands, A, Sutherland, C, Irvine, AD, McLean, WH, Filaggrin in the frontline: role in skin barrier function and disease., Journal of Cell Science, 122, (Pt 9), 2009, p1285-1294 Journal Article, 2009 URL DOI TARA - Full Text

Fallon, PG, Sasaki, T, Sandilands, A, Campbell, LE, Saunders, SP, Mangan, NE, Callanan, JJ, Kawasaki, H, Shiohama, A, Kubo, A, Sundberg, JP, Presland, RB, Fleckman, P, Shimizu, N, Kudoh, J, Irvine, AD, Amagai, M, McLean, WH, A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming., Nature Genetics, 41, (5), 2009, p602 - 608 Journal Article, 2009 DOI

O'Regan, G.M., Irvine, A.D., Yao, N., O'Marcaigh, A., Sheridan-Pereira, M., Phelan, E., McDermott, M.B., (...), Watson, R., Mediastinal and neck kaposiform hemangioendothelioma , Pediatric Dermatology, 26, (3), 2009, p331-337 Journal Article, 2009 DOI

Sun M, Li N, Dong W, Chen Z, Liu Q, Xu Y, He G, Shi Y, Li X, Hao J, Luo Y, Shang D, Lv D, Ma F, Zhang D, Hua R, Lu C, Wen Y, Cao L, Irvine AD, McLean WH, Dong Q, Wang MR, Yu J, He L, Lo WH, Zhang X, Copy-number mutations on chromosome 17q24.2-q24.3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasia., American journal of human genetics, 84, (6), 2009, p807-13 Journal Article, 2009

Irvine, AD., Towards a unified classification of the ectodermal dysplasias: Opportunities outweigh challenges. , American Journal Of Medical Genetics Part A, 149A, (9), 2009, p1970-1972 Journal Article, 2009 TARA - Full Text DOI

Genetics in, editor(s)Beiber T, Leung D , Atopic Dermatitis, London, Informa Healthcare, 2009, [Weidinger S, Rodriguez E, Irvine AD] Book Chapter, 2009

Wen, Y, Liu, Y, Xu, Y, Zhao, Y, Hua, R, Wang, K, Sun, M, Li, Y, Yang, S, Zhang, XJ, Kruse, R, Cichon, S, Betz, RC, Nöthen, MM, van Steensel, MA, van Geel, M, Steijlen, PM, Hohl, D, Huber, M, Dunnill, GS, Kennedy, C, Messenger, A, Munro, CS, Terrinoni, A, Hovnanian, A, Bodemer, C, de Prost, Y, Paller, AS, Irvine, AD, Sinclair, R, Green, J, Shang, D, Liu, Q, Luo, Y, Jiang, L, Chen, HD, Lo, WH, McLean, WH, He, CD, Zhang, X, Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis., Nature genetics, 41, (2), 2009, p228 - 233 Journal Article, 2009 URL DOI

Sun M, Li N, Dong W, Chen Z, LiuQ, XuY, He G, Shi Y, Li X, Hao J, Luo Y, Shang D, Lv D, Ma F, Zhang D, Hua R, Lu C, Wen Y, Cao L, Irvine AD, McLean WHI, Dong Q, Wang M-R, Yu J, He L, Lo WHY, Zhang X, Copy number mutations on chromosome 17q24.2-q24.3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasia, American Journal of Human Genetics, 84, (6), 2009, p807-813. Journal Article, 2009 DOI

O'Regan GM, Irvine AD, Yao N, O'Marcaigh A, Sheridan-Pereira M, Phelan E, McDermott MB, Twomey A, Russell J, Watson R, Mediastinal and neck kaposiform hemangioendothelioma: report of three cases., Pediatric dermatology, 26, (3), 2009, p331-7 Journal Article, 2009

Wen, Y., Liu, Y., Xu, Y., Zhao, Y., Hua, R., Wang, K., Sun, M., Li, Y., Yang, S., Zhang, X.-J., Kruse, R., Cichon, S., Betz, R.C., Nöthen, M.M., Van Steensel, M.A.M., Van Geel, M., Steijlen, P.M., Hohl, D., Huber, M., Dunnill, G.S., Kennedy, C., Messenger, A., Munro, C.S., Terrinoni, A., Hovnanian, A., Bodemer, C., De Prost, Y., Paller, A.S., Irvine, A.D., Sinclair, R., Green, J., Shang, D., Liu, Q., Luo, Y., Jiang, L., Chen, H.-D., Lo, W.H.-Y., McLean, W.H.I., He, C.-D., Zheng, X., Erratum: Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis (Nature Genetics (2009) 41 (228-233)), Nature Genetics, 41, (6), 2009 Journal Article, 2009

Irvine AD, Towards a unified classification of the ectodermal dysplasias: opportunities outweigh challenges., American journal of medical genetics. Part A, 149A, (9), 2009, p1970-2 Journal Article, 2009

Rodríguez E, Baurecht H, Herberich E, Wagenpfeil S, Brown SJ, Cordell HJ, Irvine AD, Weidinger S, Meta analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease, Journal of Allergy and Clinical Immunology, 123, (6), 2009, p1361-1370.e7 Journal Article, 2009 DOI

McLean, W.H.I., Palmer, C.N.A., Henderson, J., Kabesch, M., Weidinger, S., Irvine, A.D., Filaggrin variants confer susceptibility to asthma , Journal of Allergy and Clinical Immunology, 121, (5), 2008, p1294-1295 Journal Article, 2008 DOI

Genomics of the Epidermis and Appendages, Skin Pigmentation, And Skin Cancer in, editor(s)Kumar D, Weatherall D , Genomics and Clinical Medicine, New York , Oxford University Press, 2008, pp507-529 , [Healy E, Irvine AD, Lear JT, Munro CS] Book Chapter, 2008

Grainne M. O'Regan, Aileen Sandilands, WH Irwin McLean and Alan D. Irvine , Current Perspectives Series: Filaggrin in Atopic Dermatitis, Journal of Allergy and Clinical Immunology, 122, (4), 2008, p689-693 Journal Article, 2008 TARA - Full Text

Kezic S, Kemperman PMJH, Koster E, de Jongh C, Thio BH, Campbell LE, Irvine AD, McLean WHI, Puppels GJ, Caspers PJ, Loss-of-function mutations in the filaggrin gene lead to reduced levels of natural moisturizing factor in the stratum corneum, Journal of Investigative Dermatology, 128, (8), 2008, p2117-2119 Journal Article, 2008 DOI

Henderson, J, Northstone, K, Lee, SP, Liao, H, Zhao, Y, Pembrey, M, Mukhopadhyay, S, Smith, GD, Palmer, CN, McLean, WH, Irvine, AD, The burden of disease associated with filaggrin mutations: a population-based, longitudinal birth cohort study., The Journal of allergy and clinical immunology, 121, (4), 2008, p872-877 Journal Article, 2008 DOI URL

Field S, Irvine AD, Kirby B., The treatment of viral warts with topical cidofovir 1%: our experience of seven paediatric patients., British Journal of Dermatology, 160, (1), 2008, p223-224 Journal Article, 2008 DOI

Weidinger, S, Baurecht, H, Wagenpfeil, S, Henderson, J, Novak, N, Sandilands, A, Chen, H, Rodriguez, E, O'Regan, GM, Watson, R, Liao, H, Zhao, Y, Barker, JN, Allen, M, Reynolds, N, Meggitt, S, Northstone, K, Smith, GD, Strobl, C, Stahl, C, Kneib, T, Klopp, N, Bieber, T, Behrendt, H, Palmer, CN, Wichmann, HE, Ring, J, Illig, T, McLean, WH, Irvine, AD, Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk., The Journal of allergy and clinical immunology, 122, (3), 2008, p560-568.e4 Journal Article, 2008 TARA - Full Text DOI URL

Cox, D, O' Regan, G, Collins, S, Byrne, A, Irvine, A, Watson, R, Juvenile localised scleroderma: a retrospective review of response to systemic treatment., Irish Journal of Medical Science, 177, (4), 2008, p343-346 Journal Article, 2008 DOI URL

Weidinger, S, O'Sullivan, M, Illig, T, Baurecht, H, Depner, M, Rodriguez, E, Ruether, A, Klopp, N, Vogelberg, C, Weiland, SK, McLean, WH, von Mutius, E, Irvine, AD, Kabesch, M, Filaggrin mutations, atopic eczema, hay fever, and asthma in children., The Journal of allergy and clinical immunology, 121, (5), 2008, p1203-1209.e1 Journal Article, 2008 DOI URL

Brown, SJ, Irvine, AD, Atopic eczema and the filaggrin story., Seminars in cutaneous medicine and surgery, 27, (2), 2008, p128-137 Journal Article, 2008 URL DOI

O'Regan, GM, Sandilands, A, McLean, WH, Irvine, AD, Filaggrin in atopic dermatitis., The Journal of Allergy and Clinical Immunology, 122, (4), 2008, p689-693 Journal Article, 2008 DOI URL

Cusack, C, Fitzgerald, D, Clayton, TM, Irvine, AD, Successful treatment of florid cutaneous warts with intravenous cidofovir in an 11-year-old girl., Pediatric Dermatology, 25, (3), 2008, p387-389 Journal Article, 2008 URL TARA - Full Text DOI

O'Regan, GM, Irvine, AD, The role of filaggrin loss-of-function mutations in atopic dermatitis., Current opinion in allergy and clinical immunology, 8, (5), 2008 Journal Article, 2008 URL DOI

Sandilands A, Terron-Kwiatkowski A, Hull PR, O'Regan GM, Clayton TH, Watson RM, Carrick T, Evans AT, Liao H, Zhao Y, Campbell LE, Schmuth M, Gruber R, Janecke AR, Elias PM, van Steensel MAM, Nagtzaam I, van Geel M, Steijlen PM, Munro CS, Bradley DG, Palmer CNA, Smith FJD, McLean WHI, Irvine AD, Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema , Nature Genetics, 39, (5), 2007, p650 - 654 Journal Article, 2007 DOI URL

Zhao, Y, Terron-Kwiatkowski, A, Liao, H, Lee, SP, Allen, MH, Hull, PR, Campbell, LE, Trembath, RC, Capon, F, Griffiths, CE, Burden, D, McManus, R, Hughes, R, Kirby, B, Rogers, SF, Fitzgerald, O, Kane, D, Barker, JN, Palmer, CN, Irvine, AD, McLean, WH, Filaggrin null alleles are not associated with psoriasis., The Journal of investigative dermatology, 127, (8), 2007, p1878-1882 Journal Article, 2007 URL DOI

Dermatology in, editor(s)Strobel S, Smith P, El Habbal MH, Spitz, L, , The Great Ormond Street Colour Handbook of Paediatric Medicine and Surgery, London, Manson Publishing, 2007, pp131-159 , [Irvine AD, Lomas D, Atherton DJ, Harper JI ] Book Chapter, 2007

O'Connell S, O'Regan GM, Bolger T, Hoffman HM, Cant A, Irvine AD, Watson R, Response to Il-1-Receptor Antagonist in a child with Familial Cold Autoinflammatory Syndrome, Pediatric Dermatology, 24, (1), 2007, p85 - 89 Journal Article, 2007 DOI

Liao, H., Sayers, J.M., Wilson, N.J., Irvine, A.D., Mellerio, J.E., Baselga, E., Bayliss, S.J., (...), Smith, F.J.D., A spectrum of mutations in keratins K6a, K16 and K17 causing pachyonychia congenita , Journal of Dermatological Science, 48, (3), 2007, p199-205 Journal Article, 2007 DOI

Irvine AD, Fleshing out filaggrin phenotypes, Journal of Investigative Dermatology, 127, (3), 2007, p504 - 507 Journal Article, 2007 DOI

Clayton, T.H., Barry, J., Fitzgerald, D., Watson, R., Irvine, A.D., Clarithromycin suspension-associated toxic epidermal necrolysis in a 2-year-old girl [5] , Clinical and Experimental Dermatology , 32, (6), 2007, p755-756 Journal Article, 2007 DOI

Irvine AD, Fleshing out filaggrin phenotypes., The Journal of investigative dermatology, 127, (3), 2007, p504-7 Journal Article, 2007

Porokeratoses in, Wolff K, Katz S, Goldsmith L, Gilchrest B , Paller A, Leffell D , Fitzpatrick's Dermatology in General Medicine, New York , McGraw Hill, 2007, [O'Regan GM, Irvine AD] Book Chapter, 2007

Sandilands, A, Smith, FJ, Irvine, AD, McLean, WH, Filaggrin's fuller figure: a glimpse into the genetic architecture of atopic dermatitis., The Journal of Investigative Dermatology, 127, (6), 2007, p1282-1284 Journal Article, 2007 DOI URL

Disorders of cornification in, Esterly N, Eichenfield L, Frieden I , Neonatal Dermatology, Philadelphia, Elsevier, 2007, pp285-310 , [Irvine AD, Paller AS ] Book Chapter, 2007

O'Regan, GM, Zurada, J, Martinez-Mir, A, Christiano, AM, Irvine, AD, A recurrent splice-site mutation in the human hairless gene underlies congenital atrichia in Irish families., The British Journal of Dermatology, 156, (4), 2007, p744-747 Journal Article, 2007 DOI URL

McLean, WH, Irvine, AD, Disorders of keratinisation: from rare to common genetic diseases of skin and other epithelial tissues., The Ulster Medical Journal, 76, (2), 2007, p72-82 Journal Article, 2007 TARA - Full Text URL

Baurecht, H, Irvine, AD, Novak, N, Illig, T, Bühler, B, Ring, J, Wagenpfeil, S, Weidinger, S, Toward a major risk factor for atopic eczema: meta-analysis of filaggrin polymorphism data., The Journal of allergy and clinical immunology, 120, (6), 2007, p1406-1412 Journal Article, 2007 DOI URL

O'Regan, GM, Watson, R, Orr, D, O'Donovan, D, Russell, J, Phelan, E, Ryan, M, Brosnahan, O, Irvine, A, Management of vascular birthmarks: review of a multidisciplinary clinic., Irish Medical Journal, 100, (4), 2007 Journal Article, 2007 URL

Collins SM, Dominguez M, Ilmarinen T, C Costigan C, Irvine AD, Dermatological manifestations of autoimmune polyendocrinopathy - candidiasis - ectodermal dystrophy (APECED) syndrome, British Journal of Dermatology, 154, (6), 2006, p1088 - 1093 Journal Article, 2006 DOI

Smith, F.J.D., Irvine, A.D., Terron-Kwiatkowski, A., Sandilands, A., Campbell, L.E., Zhao, Y., Liao, H., Evans, A.T., Goudie, D.R., Lewis-Jones, S., Arseculeratne, G., Munro, C.S., Sergeant, A., O'Regan, G., Bale, S.J., Compton, J.G., Digiovanna, J.J., Presland, R.B., Fleckman, P., McLean, W.H.I., Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris, Nature Genetics, 38, (3), 2006, p337-342 Journal Article, 2006

Dominguez M, Crushell E, Ilmarinen T, McGovern E, Collins S, Chang B, Fleming P, Irvine AD, Brosnahan D, Ulmanen I, Murphy N, Costigan C, Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED) in the Irish Population, Journal of Pediatric Endocrinology and Metabolism, 19, (11), 2006, p1343 - 1352 Journal Article, 2006

Palmer CNA, Irvine AD, Terron-Kwiatkowski A, Zhao Y, Liao H, Lee SP, Goudie DR, Sandilands A, Campbell LE, Smith FJD, O'Regan GM, Watson RM, Cecil JE, Bale SJ, Compton JG, DiGiovanna JJ, Fleckman P, Lewis-Jones S, Arseculeratne G, Sergeant A, Munro CS, El Houate B, McElreavey K, Halkjaer LB, Bisgaard H, Mukhopadhyay S, McLean WHI, Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis, Nature Genetics, 38, (4), 2006, p441 - 446 Journal Article, 2006 DOI URL

Irvine AD and McLean WHI, Breaking the (un) sound barrier: filaggrin is a major gene for atopic dermatitis, Journal of Investigative Dermatology, 126, (6), 2006, p1200 - 1202 Journal Article, 2006 DOI

Genetics of Hidradenitis Suppurativa in, editor(s)Jemec GBE, Revuz J and Leyden JJ , Hirdadenitis Suppurativa, Berlin & Heidelberg , Springer, 2006, pp70-85 , [von der Werth J, Wood P, Irvine AD, McLean WHI ] Book Chapter, 2006

Madasseri A, McDermott MB, Irvine AD, Lipoatrophic panniculitis of the ankles, Clinical and Experimental Dermatology, 31, (2), 2006, p303 - 530 Journal Article, 2006 DOI

Sandilands A, O'Regan GM, Smith FJD, McLean WHI, Irvine AD, Prevalent and Rare Mutations in the Gene Encoding Filaggrin Cause Ichthyosis Vulgaris and Predispose Individuals to Atopic Dermatitis, Journal of Investigative Dermatology, 126, 2006, p1770 - 1775 Journal Article, 2006 DOI

Weidinger S, Illig T, Baurecht H, Irvine AD, Rodriguez E, Diaz-Lacava A, Klopp N, Wagenpfeil S, Zhao Y, Liao H, Lee SP, Palmer CNA, Jenneck C, Maintz L, Hagemann T, Behrendt H, Ring J, Nothen MM, McLean WHI, Novak N, Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations, Journal of Allergy and Clinical Immunology, 118, (1), 2006, p214 - 219 Journal Article, 2006 DOI

O'Regan, G.M., Canny, G., Irvine, A.D., 'Peeling paint' dermatitis as a presenting sign of cystic fibrosis, Journal of Cystic Fibrosis, 5, (4), 2006, p257-259 Journal Article, 2006

O'Regan GM, Canny G, Irvine AD, Peeling paint' dermatitis as a presenting sign of cystic fibrosis, Journal of Cystic Fibrosis, 5, (4), 2006, p257 - 259 Journal Article, 2006 DOI

Irvine AD, McLean WH, Breaking the (un)sound barrier: filaggrin is a major gene for atopic dermatitis., The Journal of investigative dermatology, 126, (6), 2006, p1200-2 Journal Article, 2006

Smith FJD, Irvine AD, Terron-Kwiatkowski A, Sandilands A, Campbell LE, Zhao Y, Liao L, Evans AT, Goudie DR, Lewis-Jones S, Arseculeratne G, Munro CS, Sergeant A, O'Regan G, Bale SJ, Compton JG, DiGiovanna JJ, Presland RB, Fleckman P, Irwin McLean WHI, Loss-of-function mutations in the filaggrin gene cause ichthyosis vulgaris, Nature Genetics, 38, (3), 2006, p337 - 342 Journal Article, 2006 URL DOI

O'Regan, G.M., Irvine, A.D., Disorders due to mutations in keratin genes , Giornale Italiano di Dermatologia e Venereologia, 140, (6), 2005, p667-676 Journal Article, 2005

Ectodermal dysplasias in, editor(s)Harper JI, Oranje OP, Prose N , Pediatric Dermatology , Oxford , Blackwell Scientific, 2005, pp1412-1466 , [Irvine AD] Book Chapter, 2005

Irvine AD, Inherited defects in keratins, Clinics in Dermatology, 23, (1), 2005, p6-14 Review, 2005 DOI

Tobin AM, Cotter M, Irvine AD, Kirby B, Successful treatment of a refractory verruca in a child with acute lymphoblastic leukaemia with topical cidofovir, British Journal of Dermatology, 152, (2), 2005, p386 - 388 Journal Article, 2005 DOI

McLean, W.H.I., Irvine, A.D., Hamill, K.J., Whittock, N.V., Coleman-Campbell, C.M., Mellerio, J.E., Ashton, G.S., Dopping-Hepenstal, P.J.H., Eady, R.A.J., Jamil, T., Phillips, R.J., Ghulam Shabbir, S., Haroon, T.S., Khurshid, K., Moore, J.E., Page, B., Darling, J., Atherton, D.J., van Steensel, M.A.M., Munro, C.S., Smith, F.J.D., McGrath, J.A., Erratum: An unusual N-terminal deletion of the laminin "3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome (Human Molecular Genetics (2003) vol. 12 (2395-2409)), Human Molecular Genetics, 13, (3), 2004 Journal Article, 2004

Terron-Kwiatkowski A, Terrinoni A, Didona B, Melino G, Atherton D, Irvine AD, Mclean WHI, Atypical Epidermolytic Palmoplantar Keratoderma Presentation Associated With A Mutation In The Keratin 1 Gene, British Journal of Dermatology, 150, (6), 2004, p1096 - 1103 Journal Article, 2004 DOI

Veugelers M, Wilkes D, Burton K, McDermott D, Song Y, Vaughan CJ, La Perle K, Goldstein G, Kligfield P, O'Hagan A, Bennett K, Meyer BJ, Legius E, Kartunnen M, Lavyne M, Neau J-P, Richter G, Kirali K, Stapleton K, Morelli P, Norio R, Takanashi Y, Farnsworth A, Bamforth J-S, Eitelberger F, Manfroi W, Ko GTC, Powers J, Mochizuki Y, Imai T, Driscoll DA, Goldmuntz E, Edelberg J, Eccles D, Irvine AD, McKnight GS, Basson CT, Comparative PRKAR1 a Genotype-Phenotype Analyses in Humans with Carney complex and prkar1 a Haploinsufficient Mice, Proceedings of The National Academy of Sciences, 101, (39), 2004, p14222 - 14227 Journal Article, 2004 DOI

Veugelers, M., Wilkes, D., Burton, K., McDermott, D.A., Song, Y., Goldstein, M.M., La Perle, K., (...), Basson, C.T., Erratum: Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice (Proceedings of the National Academy of Sciences of the United States of America (September 28, 2004) 101:39 (14222-14227)), 2004, - 15546 Miscellaneous, 2004 DOI

McLean, W.H.I., Irvine, A.D., Hamill, K.J., Whittock, N.V., Coleman-Campbell, C.M., Mellerio, J.E., Ashton, G.S., (...), McGrath, J.A., Erratum: An unusual N-terminal deletion of the laminin α3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome, 2004, - 2395-2409 Miscellaneous, 2004

O'Hagan, AH, Irvine AD, Sands A, O'Donaghue D, Casey F, Bingham EA, Miliary Neonatal Hemangiomatosis with Fulminant Heart Failure and Cardiac Septal Hypertrophy in Two Infants, Pediatric Dermatology, 21, (4), 2004, p469 - 472 Journal Article, 2004 DOI

Skin: Hereditary Disorders in, Cooper DN , Nature Encyclopaedia of the Human Genome, London., John Wiley and Sons Ltd, 2003, pp314-325 , [Corden LD, McLean WHI and Irvine AD] Book Chapter, 2003

McMullen EA, McCarron P, Irvine AD, Dolan OM, Allen GE, Association between long-term acitretin therapy and osteoporosis: no evidence of increased risk, Clinical and Experimental Dermatology, 28, (3), 2003, p307 - 309 Journal Article, 2003 DOI

Paller AS, Irvine AD, Russi DC, Raised limb bands developing in infancy, British Journal of Dermatology, 149, (2), 2003, p436 - 437 Journal Article, 2003 DOI

Irvine AD and McLean WHI, The Molecular Genetics of The Genodermatoses: Progress To Date And Future Directions, British Journal of Dermatology, 148, (1), 2003, p1-13 Review, 2003 DOI

McLean WH, Irvine AD, Hamill KJ, Whittock NV, Coleman-Campbell CM, Mellerio JE, Ashton GS, Dopping-Hepenstal PJ, Eady RA, Jamil T, Phillips R, Shabbir SG, Haroon TS, Khurshid K, Moore JE, Page B, Darling J, Atherton DJ, Van Steensel MA, Munro CS, Smith FJ, McGrath JA, Phillips RJ, An unusual N-terminal deletion of the laminin alpha3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome., Human molecular genetics, 12, (18), 2003, p2395-409 Journal Article, 2003

Epithelial corneal dystrophies. in, editor(s)Wang M, Flatten N , Cornea: Dystrophies and Degenerations: A Molecular Genetics Approach, San Francisco, Oxford University Press Inc, 2003, pp19-45 , [Irvine AD, Wang M, McLean WHI ] Book Chapter, 2003

Hair Loss: Genetics. in, editor(s)Cooper DN , Nature Encyclopaedia of the Human Genome, London , John Wiley and Sons Ltd, 2003, pp153-159 , [Irvine AD] Book Chapter, 2003

Irvine, A.D., McLean, W.H.I., The molecular genetics of the genodermatoses: Progress to date and future directions, British Journal of Dermatology, 148, (1), 2003, p1-13 Journal Article, 2003

Wang LL, Gannavarapu A, Clericuzio CL, Erickson RP, Irvine AD, Plon SE, Absence of RECQL4 mutations in poikiloderma with neutropenia in Navajo and non-Navajo patients, American Journal of Medical Genetics A, 118, (3), 2003, p299 - 301 Journal Article, 2003 DOI

McLean WHI, Irvine AD, Hamill KJ, Whittock NV, Coleman CM, Mellerio JE, Ashton GS, Dopping-Hepenstal PJH, Eady RAJ, Jamil T, Phillips RJ, Shabbir SG, Haroon TS, Khurshid K, Moore JE, Page B, Darling J, Atherton DJ, Munro CS, Smith FJD, McGrath JA, An unusual N-terminal deletion of the laminin α3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome, Human Molecular Genetics, 12, (18), 2003, p2395 - 2409 Journal Article, 2003 DOI

Irvine, A.D., Paller, A.S., Molecular genetics of the inherited disorders of cornification: an update., Advances in dermatology, 18, 2002, p111-149 Journal Article, 2002

Bitoun E, Chavanas S, Irvine AD, Lonie L, Bodemer C, Paradisi M, Hamel-Teillac, Ansai S, Mitsuhashi Y, Taïeb A, de Prost Y, Zambruna G, Harper JI, Hovnanian A, Netherton Syndrome: Disease expression and Spectrum of SPINK5 Mutations in 21 families, Journal of Investigative Dermatology, 118, (2), 2002, p352 - 361 Journal Article, 2002 DOI

Irvine AD, Paller AS, The Molecular Genetics of the Inherited Disorders of Keratinization: An update, Advances in Dermatology, 18, 2002, p111-49 Review, 2002

Terron-Kwiatkowski A, Paller AS, Compton J, Atherton DJ, McLean WH, Irvine AD, Two cases of primarily palmoplantar keratoderma associated with novel mutations in keratin 1., The Journal of investigative dermatology, 119, (4), 2002, p966-71 Journal Article, 2002

Irvine AD, Paller AS, Inherited disorders of Keratinization, Current Problems in Dermatology, 14, (3), 2002, p71-116 Review, 2002 DOI

Hay-Wells syndrome. in, editor(s)Gruson ES , NORD Guide to Rare Disorders, Philadelphia , Lippincott, Williams & Wilkins, 2002, pp116-117 , [Irvine AD, McGrath JA] Book Chapter, 2002

Irvine AD, Sun P, Kos L, Wang X, Paller AS, A colorimetric bead-binding assay for detection of intermolecular interactions, Experimental Dermatology, 11, (5), 2002, p465 - 471 Journal Article, 2002 DOI

Terron-Kwiatkowski A, Paller AS, Compton J, Atherton DJ, McLean WHI, Irvine AD, Two cases of primarily palmoplantar keratoderma associated with novel mutations in keratin 1, Journal of Investigative Dermatology, 119, (4), 2002, p966 - 971 Journal Article, 2002 DOI

Irvine AD, Coleman CM,. Moore JE, Swensson O, Morgan SJ, McCarthy JH, Smith FJD, Black GCM, McLean WHI, A novel mutation in KRT12 associated with Meesmann's Epithelial Corneal Dystrophy, British Journal of Ophthalmology, 86, (7), 2002, p729 - 732 Journal Article, 2002 DOI

Bitoun E, Chavanas S, Irvine AD, Lonie L, Bodemer C, Paradisi M, Hamel-Teillac D, Ansai S, Mitsuhashi Y, Taïeb A, de Prost Y, Zambruno G, Harper JI, Hovnanian A, Netherton syndrome: disease expression and spectrum of SPINK5 mutations in 21 families., The Journal of investigative dermatology, 118, (2), 2002, p352-61 Journal Article, 2002

McGrath JA, Duijf P, Doetsch V, Irvine AD, de Waal R, Vanmolkot K, Wessagowit VA, Kelly K, Atherton DJ, Griffiths WAD, Orlow SJ, van Haeringen A, Ausems M, Yang A, McKeon F, Bamshad MA, Brunner HG, Hamel BCJ, van Bokhoven H, Hay-Wells syndrome is caused by missense mutations in the SAM domain of p63, Human Molecular Genetics, 10, (3), 2001, p221 - 229 Journal Article, 2001 URL

McGrath JA, Duijf PH, Doetsch V, Irvine AD, de Waal R, Vanmolkot KR, Wessagowit V, Kelly A, Atherton DJ, Griffiths WA, Orlow SJ, van Haeringen A, Ausems MG, Yang A, McKeon F, Bamshad MA, Brunner HG, Hamel BC, van Bokhoven H, Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63., Human molecular genetics, 10, (3), 2001, p221-9 Journal Article, 2001

Irvine AD, Rugg EL, Lane EB, Hoare S, Peret C, Hughes AE, Heagerty AH, Molecular confirmation of the unique phenotype of epidermolysis bullosa simplex with mottled pigmentation, British Journal of Dermatology, 144, (1), 2001, p40 - 46 Journal Article, 2001 DOI

Irvine AD, Christiano AM, Hair on a gene string: recent advances in understanding the molecular genetics of hair loss, Clinical and Experimental Dermatology, 26, (1), 2001, p59-714 Review, 2001 DOI

O'Hagan AH, Irvine AD, Brennan T, Walsh MY, Bingham EA, Fibrous histiocytoma in a nine week old male infant, European Journal of Pediatric Dermatology, 11, (1), 2001, p13 - 18 Journal Article, 2001

Moore JE, Dua HS, Page AB, Irvine AD, Archer DB, Ocular surface reconstruction in LOGIC syndrome by amniotic membrane transplantation, Cornea, 20, (1), 2001, p753 - 756 Journal Article, 2001 DOI

Irvine AD, Smith FJD, Shum KW, Williams HC, McLean WHI, A novel mutation in the 2B domain of keratin 2e causing Ichthyosis Bullosa of Siemens, Clinical and Experimental Dermatology, 25, (8), 2000, p648 - 652 Journal Article, 2000 DOI

Chavanas S, Bodemer C, Rochat A, Hamel-Teillac D, Ali M, Irvine AD, Bonafé J-L, Taïeb A, Barrandon Y, Harper JI, de Prost, Y, Hovnanian A, Mutations in SPINK5 encoding a novel serine protease inhibitor cause Netherton Syndrome, Nature Genetics, 25, (2), 2000, p141 - 142 Journal Article, 2000 DOI URL

Smith FJD, McKenna KE, Irvine AD, Bingham EA, Coleman CM, Uitto J, McLean WHI, A mutation detection strategy for the human keratin 6A gene and novel missense mutations in two cases of pachyonychia congenita type 1, Experimental Dermatology, 8, (2), 1999, p109 - 111 Journal Article, 1999 DOI

Korge BP, Hamm H, Jury CS, Traupe H, Irvine AD, Healey E, Birch-Machin, M, Rees JL, Messenger AG, Holmes SC, Parry DAD, Munro CS, Identification of novel mutations in basic hair keratins hHb1 and hHb6 in monilethrix: implications for protein structure and clinical phenotype, Journal of Investigative Dermatology, 113, (4), 1999, p607 - 612 Journal Article, 1999 DOI

Korge BP, Hamm H, Jury CS, Traupe H, Irvine AD, Healy E, Birch-MacHin M, Rees JL, Messenger AG, Holmes SC, Parry DA, Munro CS, Identification of novel mutations in basic hair keratins hHb1 and hHb6 in monilethrix: implications for protein structure and clinical phenotype., The Journal of investigative dermatology, 113, (4), 1999, p607-12 Journal Article, 1999

Irvine AD and McLean WHI, Human keratin diseases: the increasing spectrum of disease and the subtlety of genotype-phenotype correlation, British Journal of Dermatology, 140, (5), 1999, p815-828 Review, 1999 DOI

Ahmad W, Irvine AD, Lam H, Buckley C, Bingham EA, Panteleyev AA, Ahmad A, McGrath JA, Christiano AM, A missense mutation in the zinc-finger domain of the human hairless gene underlies congenital atrichia in a family of Irish travellers, American Journal of Human Genetics, 63, (4), 1998, p984 - 991 Journal Article, 1998 DOI

Irvine AD, Bruce IN, Walsh MY, Bingham EA, Antineutrophil cytoplasmic antibodies in leukocytoclastic vasculitis, Archives of Dermatology, 134, (2), 1998, p239 - 240 Journal Article, 1998 URL

Ahmad W, Irvine AD, Lam H, Buckley C, Bingham EA, Panteleyev AA, Ahmad M, McGrath JA, Christiano AM, A missense mutation in the zinc-finger domain of the human hairless gene underlies congenital atrichia in a family of Irish travellers., American journal of human genetics, 63, (4), 1998, p984-91 Journal Article, 1998

Casey M, Mah C, Merliss AD, Kirschner LS, Taymans SE, Denio AE, Korf B, Irvine AD, Hughes AE, Carney JA, Stratakis CA, Basson CT, Identification of a novel genetic locus for familial cardiac myxoma and Carney complex, Circulation, 98, (23), 1998, p2560 - 2566 Journal Article, 1998 URL

Covello SP, Irvine AD, McKenna KE, Munro CS, Nevin NC, Smith FJD, Uitto J, McLean WHI, Mutations in keratin K9 in kindreds with epidermolytic palmoplantar keratoderma and epidemiology in Northern Ireland, Journal of Investigative Dermatology, 111, 1998, p1207 - 1209 Journal Article, 1998 DOI

O'Hagan A, Irvine AD, Allen GE, Mefenamic acid induced pseudoporphyria, British Journal of Dermatology, 139, (6), 1998, p1131 - 1132 Journal Article, 1998 DOI

O'Hagan A, Irvine AD, Walsh M, Allen GE, Pyodermatitis-pyostomatitis vegetans: evidence of an entirely mucocutaneous variant, British Journal of Dermatology, 138, (3), 1998, p552 - 555 Journal Article, 1998 DOI

O'Hagan, A.H., Irvine, A.D., Allen, G.E., Walsh, M., Pseudoporphyria induced by mefenamic acid [16], British Journal of Dermatology, 139, (6), 1998, p1131-1132 Journal Article, 1998

Sais, G., Vidaller, A., Jucgla, A., Gallardo, F., Peyri, J., Irvine, A.D., Bruce, I.N., Antineutrophil cytoplasmic antibodies in leukocytoclastic vasculitis [1] (multiple letters), Archives of Dermatology, 134, (2), 1998, p239-240 Journal Article, 1998

Casey M, Mah C, Merliss AD, Kirschner LS, Taymans SE, Denio AE, Korf B, Irvine AD, Hughes A, Carney JA, Stratakis CA, Basson CT, Identification of a novel genetic locus for familial cardiac myxomas and Carney complex., Circulation, 98, (23), 1998, p2560-6 Journal Article, 1998

Irvine AD, Armstrong DKB, Bingham EA, Hadden DR, Nevin NC, Hughes AE, Evidence for a second genetic locus in Carney complex, British Journal of Dermatology, 138, 1998, p572 - 576 Journal Article, 1998 DOI

Irvine AD, Bruce IN, Walsh MY, Bingham EA, Microscopic polyangiitis. Delineation of a cutaneous-limited variant associated with antimyeloperoxidase autoantibody., Archives of Dermatology, 133, (4), 1997, p474 - 477 Journal Article, 1997 URL

Irvine AD, McKenna KE, Jenkinson H, Hughes AE, A mutation in the V1 Domain of keratin 5 causes Epidermolysis Bullosa Simplex with Mottled Pigmentation, Journal of Investigative Dermatology, 108, (5), 1997, p809 - 810 Journal Article, 1997 DOI

Irvine AD, Corden LD, Swensson O, Swensson B, Moore JE, Frazer DG, Smith FJD, Knowlton RG, Christophers E, Rochels R, Uitto J, McLean WHI., Mutations in cornea-specific keratins K3 or K12 cause Meesmann's corneal dystrophy, Nature Genetics, 16, 1997, p184 - 187 Journal Article, 1997 URL

Loughrey MB, Irvine AD, Girdwood RWA, McMillan CM, Cutaneous larva migrans: the case for routine oral treatment, British Journal of Dermatology, 137, (1), 1997, p155 - 158 Journal Article, 1997

Armstrong DKB, Irvine AD, Handley JM, Walsh MY, Hadden DR, Bingham EA, Carney complex: report of a new kindred with predominantly cutaneous manifestations, British Journal of Dermatology, 136, (4), 1997, p578 - 582 Journal Article, 1997 DOI

Irvine AD, McKenna KE, Bingham A, Nevin NC, Hughes AE, A novel mutation in the helix termination peptide of keratin 5 causing epidermolysis bullosa simplex Dowling-Meara., The Journal of investigative dermatology, 109, (6), 1997, p815-6 Journal Article, 1997

Irvine AD, McKenna KE, Bingham EA, Nevin NC, Hughes AE, A novel mutation in the helix termination peptide of keratin 5 causing Epidermolysis bullosa simplex Dowling-Meara, Journal of Investigative Dermatology, 109, 1997, p815 - 816 Journal Article, 1997 DOI

Irvine AD, Dolan OM, Hadden DR, Stewart FJ, Bingham EA, Nevin NC, An autosomal dominant syndrome of acromegaloid facial appearance and generalised hypertrichosis terminalis., Journal of medical genetics, 33, (11), 1996, p972-4 Journal Article, 1996

Irvine AD, Stewart FJ, Bingham EA, Nevin NC, Boston VE, Focal dermal hypoplasia (Goltz Syndrome) associated with intestinal malrotation and mediastinal dextroposition., American Journal of Medical Genetics, 62, (3), 1996, p213-215 Journal Article, 1996 DOI

Irvine AD, Sweeney LE, Corbett JR, Lymphangioma circumscriptum associated with paravesical cystic retroperitoneal lymphangioma, British Journal of Dermatology, 134, (6), 1996, p1135 - 1137 Journal Article, 1996 DOI

Irvine AD, Stewart FJ, Bingham EA, Nevin NC, Boston VE, Focal dermal hypoplasia (Goltz Syndrome) associated with intestinal malrotation and mediastinal dextroposition, American Journal of Medical Genetics, 62, (3), 1996, p213 - 215 Journal Article, 1996 DOI

Irvine AD, Dolan OM, Hadden DR, Stewart FJ, Bingham EA, Nevin NC, An autosomal dominant syndrome of acromegaloid facial appearance and generalised hypertrichosis terminalis, Journal of Medical Genetics, 33, (11), 1996, p972 - 974 Journal Article, 1996 URL

Irvine AD, Kenny B, Walsh MY, Burrows D, Primary cutaneous adenoid cystic carcinoma, Clinical and Experimental Dermatology, 21, 1996, p249 - 250 Journal Article, 1996 URL

Irvine AD, Bruce IN, Walsh M, Burrows D, Handley J, Dermatological presentation of ANCA associated disease: a report of two contrasting cases and review of the literature, British Journal of Dermatology, 134, (5), 1996, p924 - 928 Journal Article, 1996

Irvine, A.D., Bruce, I.N., Walsh, M., Burrows, D., Handley, J., Dermatological presentation of disease associated with antineutrophil cytoplasmic antibodies: A report of two contrasting cases and a review of the literature, British Journal of Dermatology, 134, (5), 1996, p924-928 Journal Article, 1996

Armstrong DKB, Irvine A, Walsh MY, Mayne EE, Burrows D, Multiple dermatofibromas in a patient with HIV infection, Clinical and Experimental Dermatology, 20, (6), 1995, p474 - 476 Journal Article, 1995 DOI

Dolan OM, Burrows D, Irvine A, Walsh M, The value of a baseline liver biopsy prior to methotrexate therapy, British Journal of Dermatology, 131, (6), 1994, p891 - 894 Journal Article, 1994 DOI

Sakas, D.E., O"Connor, G., Singh, J., Dias, L., Eljamel, M.S., Mathew, B., Clements, B., Irvine, A., Gray, W.J., Byrnes, D.P., Bailey, I.C., Pathirana, N., Refsum, S., Bell, K.E., McKinstry, C.S., Callaghan, N., Crowley, M., Goggin, T., MacDermott, N., O"Driscoll, K.J., Neary, D., Pearson, N.A., Snowden, J.S., Brown, S., Vaughan, M., McMackin, D., Phillips, J., Burke, T., Murphy, S., Staunton, H., Cristea, R.L., Hourihane, M., Farrell, M.A., Morrison, P.J., Nevin, N.C., Collins, A.D., Gibson, M., Behan, W.M.H., Simpson, K.S., Cavanagh, H.M., Gow, J.W., Gillespie, J.S., Behan, P.O., Sklar, R.M., Brown, R.H., Gillian, A.M., O"Mahony, D., Breen, K.C., Hutchinson, J., Burke, T., Hutchinson, M., Droogan, A.G., Crockard, A.D., Hawkins, S.A., McNeill, T.A., Gutowski, N.J., Chirico, S., Pinkham, J.M., Smith, C., Akanu, D., Kaur, H., Strange, R.C., Halliwell, B., Murphy, R.P., Rogers, L., Weick, J., Estes, M., Elrington, G.M., Morris, C.S., Reffin, J.P., Tregear, S.J., Ripley, L.J., Rees, J.E., Irvine, A.D., O"Brien, D.P., Dias, P.S., Herity, N., Hawkins, S., McMenamin, J.B., Mirakhur, M., Allen, I.V., Bresnihan, B., Fitzsimmons, M., Sawhney, B., Patterson, V., Bailey, I.C., Byrnes, D., Watt, M., Lee, K.-C., Redmond, J.M.T., McKenna, M.J., Feingold, M., Ahmad, B.K., Watt, M., Cunningham, R.T., Winder, J., Lawson, J.A., Johnston, C.F., Buchanan, K.D., Dean, G., Elian, M., Gray, W.P., Ryder, D.Q., Buckley, T.F., Breathnach, K., Ooi, A., Farrell, M., Doherty, C., Hayes, F.J., Redmond, J.J.T., McKenna, M.M., Redmond, J.M.T., Farrell, M., Watt, M., Gibson, J.M., Patterson, V.H., Redmond, J.M.T., McKenna, M.J., Feingold, M., Ahmad, B.K., Moran, M., Burke, M., King, M.D., Moran, M., Burke, M., Hardiman, O., Reid, V., Dowd, J.O., Murphy, R., Rashad, E., Toland, J., Phillips, J.P., Staunton, H., Shu-Ming, P., Coughlin, A., Phillips, J.P., McCoy, D.M., Qureshi, A., Black, M.A., Grace, P.A., Bouchier-Hayes, D., Dwyer, R., Irish neurological association: Proceedings of 28th annual meeting, beaumont hospital, Dublin, 15th-16th may, 1992, Irish Journal of Medical Science, 162, (11), 1993, p474-484 Journal Article, 1993

Research Expertise

Keywords

atopy; DERMATITIS; DERMATOLOGY; eczema; Genetic/Molecular epidemiology; Genomic structure and function, molecular approaches to gene function; Human genetics; Mammilian and human genetics and genomics; Molecular population genetics

Recognition

Representations

Grant Reviewer: The Wellcome Trust, Medical Research Council (UK), The Italian National Telethon, DEBRA International, British Skin Foundation Current

Reviewer: The Journal of Investigative Dermatology, The British Journal of Dermatology, Experimental Dermatology, European Journal of Human Genetics, Clinical and Experimental Dermatology, Journal of Allergy And Clinical Immunology, Allergy Current

Editorial Board: Journal of Lymphoedema 2007- present

Editorial Board Member: Faculty of 1000 Medicine (F1000), Paediatric Dermatology Section 2007- present

Editorial Board Member: Pediatric Dermatology 2006- present

Awards and Honours

Fellowship (FRCP) Royal College of Physicians of London 2008

Paul Gerson Unna Prize 2007

Prix de La Foundation La Roche-Posay 2006

Fulbright Scholarship 2000

Geoffrey Dowling Fellowship, British Association of Dermatologists 2000

Canadian Dermatology Association Prize, Best paper presented at the British Association of Dermatologists Annual Meeting 2000

Young Investigator Fellowship, British Society for Investigative Dermatology 1999

Memberships

Association of Physicians of Great Britain & Ireland - Member 2008- – Current

Royal College of Physicians of London - Fellow 2007- – Current

The Royal College of Physicians of Ireland - Fellow 2004- – Current

American Academy of Dermatology International - Fellow 2001- – 2010

Society for Pediatric Dermatology - Member 2001- – 2010

British Association of Dermatologists - Ordinary Member 2001- – Current

Irish Association of Dermatologists - Member 1999- – Current

Irish Society of Human Genetics - Member 1999- – Current

British Society for Pediatric Dermatology - Member 1995 – Current

Royal Academy of Medicine in Ireland - Member 1998- – Current

European Society for Dermatological Research - Member 1998- – Current

Society for Investigative Dermatology - Member 1996- – Current

British Society for Investigative Dermatology - Member 1996- – Current

The Dowling Club - Member 1994- – Current