Professor Nicki Panoskaltsis

Professor Nicki Panoskaltsis

Professor in Personalised Therapeutics, Pharmacy

Publications and Further Research Outputs

  • Abdelaal Ahmed Mahmoud M Alkhatip, A., Conroy, P., Hamza, M.K., Murphy, I., Purcell, A., McGuire, D., The authors reply, Critical Care Medicine, 48, (8), 2020, pE731-E732Journal Article, 2020
  • Allenby M.C., Okutsu N., Brailey K., Guasch J., Zhang Q., Panoskaltsis N., Mantalaris A., A Spatiotemporal Microenvironment Model to Improve Design of a Three-Dimensional Bioreactor for Red Cell Production, Tissue Engineering - Part A, 28, (1-2), 2022, p38 - 53, p38-53Journal Article, 2022, DOI
  • Panoskaltsis N., McCarthy N.E., Stagg A.J., Mummery C.J., Husni M., Arebi N., Greenstein D., Price C.L., Al-Hassi H.O., Koutinas M., Mantalaris A., Knight S.C., Immune reconstitution and clinical recovery following anti-CD28 antibody (TGN1412)-induced cytokine storm, Cancer Immunology, Immunotherapy, 70, (4), 2021, p1127 - 1142, p1127-1142Journal Article, 2021, DOI
  • Karakostas P., Panoskaltsis N., Mantalaris A., Georgiadis M.C., Optimization of CAR T-cell therapies supply chains, Computers and Chemical Engineering, 139, 2020Journal Article, 2020, DOI
  • Gyorgy R., Klontzas M.E., Kostoglou M., Panoskaltsis N., Mantalaris A., Georgiadis M.C., Capturing mesenchymal stem cell heterogeneity during osteogenic differentiation: an experimental-modeling approach, Industrial and Engineering Chemistry Research, 58, (31), 2019, p13900 - 13909, p13900-13909Journal Article, 2019, DOI
  • Klontzas M.E., Reakasame S., Silva R., Morais J.C.F., Vernardis S., MacFarlane R.J., Heliotis M., Tsiridis E., Panoskaltsis N., Boccaccini A.R., Mantalaris A., Oxidized alginate hydrogels with the GHK peptide enhance cord blood mesenchymal stem cell osteogenesis: A paradigm for metabolomics-based evaluation of biomaterial design, Acta Biomaterialia, 88, 2019, p224 - 240, p224-240Journal Article, 2019, DOI
  • Tahlawi A., Klontzas M.E., Allenby M.C., Morais J.C.F., Panoskaltsis N., Mantalaris A., RGD-functionalized polyurethane scaffolds promote umbilical cord blood mesenchymal stem cell expansion and osteogenic differentiation, Journal of Tissue Engineering and Regenerative Medicine, 13, (2), 2019, p232 - 243, p232-243Journal Article, 2019, DOI
  • Mortera-Blanco T., Rende M., Panoskaltsis N., Mantalaris A., Tissue engineering of normal and abnormal bone marrow, Comprehensive Biotechnology, 2019, p225 - 235, p225-235Journal Article, 2019, DOI
  • Allenby M.C., Panoskaltsis N., Tahlawi A., Dos Santos S.B., Mantalaris A., Dynamic human erythropoiesis in a three-dimensional perfusion bone marrow biomimicry, Biomaterials, 188, 2019, p24 - 37, p24-37Journal Article, 2019, DOI , TARA - Full Text
  • Misener R., Allenby M.C., Fuentes-Gari M., Gupta K., Wiggins T., Panoskaltsis N., Pistikopoulos E.N., Mantalaris A., Stem cell biomanufacturing under uncertainty: A case study in optimizing red blood cell production, AIChE Journal, 64, (8), 2018, p3011 - 3022, p3011-3022Journal Article, 2018, DOI
  • Quiroga-Campano A.L., Panoskaltsis N., Mantalaris A., Energy-based culture medium design for biomanufacturing optimization: A case study in monoclonal antibody production by GS-NS0 cells, Metabolic Engineering, 47, 2018, p21 - 30, p21-30Journal Article, 2018, DOI
  • Allenby M.C., Tahlawi A., Morais J.C.F., Li K., Panoskaltsis N., Mantalaris A., Ceramic hollow fibre constructs for continuous perfusion and cell harvest from 3D hematopoietic organoids, Stem Cells International, 2018, 2018Journal Article, 2018, DOI
  • Perl A.E., Hosono N., Montesinos P., Podoltsev N., Martinelli G., Panoskaltsis N., Recher C., Smith C.C., Levis M.J., Strickland S., Rollig C., Gross-Langenhoff M., Chou W.-C., Lee J.-H., Yokoyama H., Hasabou N., Lu Q., Tiu R.V., Altman J.K., Clinical outcomes in patients with relapsed/refractory FLT3-mutated acute myeloid leukemia treated with gilteritinib who received prior midostaurin or sorafenib, Blood Cancer Journal, 12, (5), 2022Journal Article, 2022, DOI
  • Dennis M., Burnett A., Hills R., Thomas I., Ariti C., Severinsen M.T., Hemmaway C., Greaves P., Clark R.E., Copland M., Russell N., Kallenbach M., Culligan D., Duncan C., Krishnamurthy P., Cuthbert A., Patalappa C., Spanoudakis M., Galvani D., Berkahn I., Patton N., Pemberton L., Virchis A., Jasani P., Parker A., Arnold C., Cuthbert R., Finnega D., Nikolousis M., Pratt G., Cahalin P., Ackroyd S., Mehta P., Protheroe R., Weinkove R., Ali S., Welch E., Smith M., Spearing R., Vyas P., Campbell G., Hamblin M., Wood M., Gupta S., Westonsmith S., Pillai A., Hunter H., Rule S., Neilson R., Lush R., Rothwell K., Swe W., Chalmers I., Prahladan M., Kwan M., Lyttleton M., Hunter A., Martin A.M., Saravanamuttu K., Saif M., Tholouli E., Andrews V., Jackson S., Rajagopal R., Morrison A., Gordon W., Mitchell L., Bowen A., McGrann A., Mittal S., Panoskaltsis N., Byrne J., Das-Gupta E., Radia R., Baker B., Kilfoyle A., Knottenbelt E., Rinaldi C., Moreton P., Furby D., Jack F., Alderman C., Belsham E., Corser R., Cranfield T., Dignum H., James C., Gudgin E., Mohan M., Kampman P., Kjeldsen L., Mourek J., Nielsen O.J., Niemann C.U., Grech H., Khan A., Sampson R., Creagh D., Szabo F., Coppell J., Veale D., Kottaridis P., Fernandes S., Cullis J., Grand E., Wandroo F., Mohite U., O'Brien D., Nicholson T., Janes S., Aitchison R., Galloway M., Mathew S., Blesing N., Green S., Mamadigi R., Plews D., Chacko J., Salim R., Allameddine A., Greenfield H., Osborne D., Hodges G., Lai H.C., Carrington P., Sadik W., Yung L., Lokare A., Alvares C., Knapper S., Goodman H., Islam S., Aitchison R., Pattinson J., Pushkaran B., Heartin E., Edwards D., Seale J., A randomised evaluation of low-dose cytosine arabinoside (ara-C) plus tosedostat versus low-dose ara-C in older patients with acute myeloid leukaemia: results of the LI-1 trial, British Journal of Haematology, 194, (2), 2021, p298 - 308, p298-308Journal Article, 2021, DOI
  • Panoskaltsis N., Are all cytokine storms the same?, Cancer Immunology, Immunotherapy, 70, (4), 2021, p887 - 892, p887-892Journal Article, 2021, DOI
  • McCarthy N.E., Stagg A.J., Price C.L., Mann E.R., Gellatly N.L., Al-Hassi H.O., Knight S.C., Panoskaltsis N., Patients with gastrointestinal irritability after TGN1412-induced cytokine storm displayed selective expansion of gut-homing "ß and ""T cells, Cancer Immunology, Immunotherapy, 70, (4), 2021, p1143 - 1153, p1143-1153Journal Article, 2021, DOI
  • Panoskaltsis N., McCarthy N.E., Knight S.C., Myelopoiesis of acute inflammation: lessons from TGN1412-induced cytokine storm, Cancer Immunology, Immunotherapy, 70, (4), 2021, p1155 - 1160, p1155-1160Journal Article, 2021, DOI
  • Harrison C.N., Mead A.J., Panchal A., Fox S., Yap C., Gbandi E., Houlton A., Alimam S., Ewing J., Wood M., Chen F., Coppell J., Panoskaltsis N., Knapper S., Ali S., Hamblin A., Scherber R., Dueck A.C., Cross N.C.P., Mesa R., McMullin M.F., Ruxolitinib vs best available therapy for et intolerant or resistant to hydroxycarbamide, Blood, 130, (17), 2017, p1889 - 1897, p1889-1897Journal Article, 2017, DOI
  • Gyorgy R., Klontzas M.E., Kostoglou M., Panoskaltsis N., Mantalaris A., Georgiadis M.C., A Population Balance Model for Stem Cell Differentiation Bioprocesses, Computer Aided Chemical Engineering, 40, 2017, p2761 - 2766, p2761-2766Journal Article, 2017, DOI
  • Gyorgy R., Klontzas M.E., Kostoglou M., Panoskaltsis N., Georgiadis M.C., Mantalaris A., An Integrated Experimental-Modelling Approach of Mesenchymal Stem Cell Bioprocess towards Osteogenic Differentiation, IFAC-PapersOnLine, 50, (1), 2017, p9877 - 9882, p9877-9882Journal Article, 2017, DOI
  • Vernardis S.I., Terzoudis K., Panoskaltsis N., Mantalaris A., Human embryonic and induced pluripotent stem cells maintain phenotype but alter their metabolism after exposure to ROCK inhibitor, Scientific Reports, 7, 2017Journal Article, 2017, DOI
  • Allenby M.C., Misener R., Panoskaltsis N., Mantalaris A., A Quantitative Three-Dimensional Image Analysis Tool for Maximal Acquisition of Spatial Heterogeneity Data, Tissue Engineering - Part C: Methods, 23, (2), 2017, p108 - 117, p108-117Journal Article, 2017, DOI
  • Blanco T.M., Mantalaris A., Bismarck A., Panoskaltsis N., The development of a three-dimensional scaffold for ex vivo biomimicry of human acute myeloid leukaemia, Biomaterials, 31, (8), 2010, p2243 - 2251, p2243-2251Journal Article, 2010, DOI , TARA - Full Text
  • Mortera-Blanco T., Mantalaris A., Bismarck A., Aqel N., Panoskaltsis N., Long-term cytokine-free expansion of cord blood mononuclear cells in three-dimensional scaffolds, Biomaterials, 32, (35), 2011, p9263 - 9270, p9263-9270Journal Article, 2011, DOI , TARA - Full Text
  • Pefani E., Panoskaltsis N., Mantalaris A., Georgiadis M.C., Pistikopoulos E.N., Chemotherapy drug scheduling for the induction treatment of patients with acute myeloid leukemia, IEEE Transactions on Biomedical Engineering, 61, (7), 2014, p2049 - 2056, p2049-2056Journal Article, 2014, DOI , TARA - Full Text
  • Burnett, A.K., Russell, N., Hills, R.K., Panoskaltsis, N., Khwaja, A., Hemmaway, C., Cahalin, P., Clark, R.E., Milligan, D., A randomised comparison of the novel nucleoside analogue sapacitabine with low-dose cytarabine in older patients with acute myeloid leukaemia, Leukemia, 29, (6), 2015, p1312-1319Journal Article, 2015, DOI
  • Fuentes-Garí, M., Velliou, E., Misener, R., Pefani, E., Rende, M., Panoskaltsis, N., Mantalaris, A., Pistikopoulos, E.N., A systematic framework for the design, simulation and optimization of personalized healthcare: Making and healing blood, Computers and Chemical Engineering, 81, 2015, p80-93Journal Article, 2015, DOI
  • Fuentes-Garí, M., Misener, R., Pefani, E., García-Münzer, D., Kostoglou, M., Georgiadis, M.C., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Cell cycle model selection for leukemia and its impact in chemotherapy outcomes, Computer Aided Chemical Engineering, 37, 2015, p2159-2164Journal Article, 2015, DOI
  • Fuentes-Ga", M., Misener, R., Georgiadis, M.C., Kostoglou, M., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Chemotherapy optimization in Leukemia: Selecting the right mathematical models for the right biological processes, IFAC-PapersOnLine, 28, (20), 2015, p534-539Journal Article, 2015, DOI
  • Savvopoulos, S., Misener, R., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Global Sensitivity Analysis for a Model of B-Cell Chronic Lymphocytic Leukemia Disease Trajectories, Computer Aided Chemical Engineering, 37, 2015, p185-190Journal Article, 2015, DOI
  • Fauzi, I., Panoskaltsis, N., Mantalaris, A., In vitro differentiation of embryonic stem cells into hematopoietic lineage: Towards erythroid progenitor"s production, Methods in Molecular Biology, 1341, 2015, p217-234Journal Article, 2015, DOI
  • Kostoglou, M., Fuentes-Garí, M., García-Münzer, D., Georgiadis, M.C., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Mathematical analysis of multistage population balances for cell growth and death, Computer Aided Chemical Engineering, 37, 2015, p2105-2110Journal Article, 2015, DOI
  • Fuentes-Garí, M., Misener, R., Georgiadis, M.C., Kostoglou, M., Panoskaltsis, N., Mantalaris, A., Pistikopoulos, E.N., Selecting a Differential Equation Cell Cycle Model for Simulating Leukemia Treatment, Industrial and Engineering Chemistry Research, 54, (36), 2015, p8847-8859Journal Article, 2015, DOI
  • Velliou, E.G., Dos Santos, S.B., Papathanasiou, M.M., Fuentes-Gari, M., Misener, R., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Towards unravelling the kinetics of an acute myeloid leukaemia model system under oxidative and starvation stress: A comparison between two- and three-dimensional cultures, Bioprocess and Biosystems Engineering, 38, (8), 2015, p1589-1600Journal Article, 2015, DOI
  • Dennis, M., Russell, N., Hills, R.K., Hemmaway, C., Panoskaltsis, N., McMullin, M.-F., Kjeldsen, L., Dignum, H., Thomas, I.F., Clark, R.E., Milligan, D., Burnett, A.K., Vosaroxin and vosaroxin plus low-dose Ara-C (LDAC) vs low-dose Ara-C alone in older patients with acute myeloid leukemia, Blood, 125, (19), 2015, p2923-2932Journal Article, 2015, DOI
  • Fuentes-Gari, M., Misener, R., Garcia-Munzer, D., Velliou, E., Georgiadis, M.C., Kostoglou, M., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Towards personalized treatments for leukemia based on cell cycle heterogeneity: An experimental/modeling approach, Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting, 1, 2014, p210-211Journal Article, 2014
  • Pefani, E., Panoskaltsis, N., Velliou, E., Fuentes, M., Mantalaris, A., Georgiadis, M.C., Pistikopoulos, E.N., An automated system for the design of optimal personalized chemotherapy protocols for the treatment of Leukemia, Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future, 2013, p362-364Journal Article, 2013
  • Pefani, E., Panoskaltsis, N., Mantalaris, A., Georgiadis, M.C., Pistikopoulos, E.N., Design of optimal patient-specific chemotherapy protocols for the treatment of acute myeloid leukemia (AML), Computers and Chemical Engineering, 57, 2013, p187-195Journal Article, 2013, DOI
  • Velliou, E.G., Garí, M.F., Dos Santos, S.B., Misener, R., Panoskaltsis, N., Mantalaris, A., Pistikopoulos, E.N., The effect of oxygen and glucose stress on the evolution of a leukaemia model system in an in vitro bone marrow biomimicry, Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future, 2013, p573-575Journal Article, 2013
  • Fuentes Garí, M., Velliou, E.G., Misener, R., Brito Dos Santos, S., Panoskaltsis, N., Mantalaris, A., Pistikopoulos, E.N., Towards a personalised treatment of acute myeloid leukaemia: The impact of considering the cell cycle, Materials Engineering and Sciences Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future, 2013, p678-680Journal Article, 2013
  • Suntharalingam, G., Perry, M.R., Ward, S., Brett, S.J., Castello-Cortes, A., Brunner, M.D., Panoskaltsis, N., Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412, New England Journal of Medicine, 355, (10), 2006, p1018-1028Journal Article, 2006, DOI
  • Pavlu, J., Jackson, M., Panoskaltsis, N., GM1-gangliosidosis type I, British Journal of Haematology, 135, (4), 2006, p422Journal Article, 2006, DOI
  • Kumar, R., Ngai, S., Bardsley, M., Panoskaltsis, N., Stepanek, F., Mantalaris, A., Bone marrow oxygen transport model in sickle cell disease, Proceedings of the 3rd IASTED International Conference on Biomedical Engineering 2005, 2005, p300-304Journal Article, 2005
  • Panoskaltsis, N., Dendritic cells in MDS and AML - Cause, effect or solution to the immune pathogenesis of disease?, Leukemia, 19, (3), 2005, p354-357Journal Article, 2005, DOI
  • Pavlu, J., Panoskaltsis, N., Dysplastic polychromatic "snowmoblast", Blood, 106, (12), 2005, p3689Journal Article, 2005, DOI
  • Panoskaltsis, N., Mantalaris, A., Wu, J.H.D., Engineering a mimicry of bone marrow tissue ex vivo, Journal of Bioscience and Bioengineering, 100, (1), 2005, p28-35Journal Article, 2005, DOI
  • Safinia, L., Panoskaltsis, N., Mantalaris, A., Haematopoietic culture systems, Bioreactors for Tissue Engineering: Principles, Design and Operation, 2005, p309-334Journal Article, 2005
  • Panoskaltsis, N., Reid, C.D.L., Knight, S.C., Immune modulation with dendritic cells, Transfusion Medicine, 14, (2), 2004, p81-96Journal Article, 2004, DOI
  • Panoskaltsis, N., Reid, C.D.L., Knight, S.C., Quantification and cytokine production of circulating lymphoid and myeloid cells in acute myelogenous leukaemia, Leukemia, 17, (4), 2003, p716-730Journal Article, 2003, DOI
  • Garí, M.F., Velliou, E.G., Misener, R., Dos Santos, S.B., Panoskaltsis, N., Mantalaris, A., Pistikopoulos, E.N., Towards a personalised treatment of acute myeloid leukaemia: The impact of considering the cell cycle, Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future, 2013, p769-771Journal Article, 2013
  • Krieger, A., Panoskaltsis, N., Mantalaris, A., Georgiadis, M.C., Pistikopoulos, E.N., Analysis of an individualized physiologically based model for anesthesia control, IFAC Proceedings Volumes (IFAC-PapersOnline), 45, (18), 2012, p385-390Journal Article, 2012, DOI
  • Pefani, E., Panoskaltsis, N., Mantalaris, A., Georgiadis, M.C., Pistikopoulos, E.N., Design of optimal disease and patient-specific chemotherapy protocols for the treatment of Acute Myeloid Leukaemia (AML), Computer Aided Chemical Engineering, 31, 2012, p1717-1721Journal Article, 2012, DOI
  • Fauzi, I., Panoskaltsis, N., Mantalaris, A., Enhanced hematopoietic differentiation toward erythrocytes from murine embryonic stem cells with hepG2-conditioned medium, Stem Cells and Development, 21, (17), 2012, p3152-3161Journal Article, 2012, DOI
  • Mortera-Blanco, T., Rende, M., Macedo, H., Farah, S., Bismarck, A., Mantalaris, A., Panoskaltsis, N., Ex vivo mimicry of normal and abnormal human hematopoiesis, Journal of Visualized Experiments, (62), 2012Journal Article, 2012, DOI
  • Ma, C.Y.J., Panoskaltsis, N., Kumar, R., Xu, X.Y., Mantalaris, A., Simulation of ex vivo bone marrow culture: Application to chronic myeloid leukaemia growth model, Biochemical Engineering Journal, 61, 2012, p66-77Journal Article, 2012, DOI
  • Lim, M., Shunjie, C., Panoskaltsis, N., Mantalaris, A., Systematic experimental design for bioprocess characterization: Elucidating transient effects of multi-cytokine contributions on erythroid differentiation, Biotechnology and Bioprocess Engineering, 17, (1), 2012, p218-226Journal Article, 2012, DOI
  • Krieger, A., Panoskaltsis, N., Mantalaris, A., Georgiadis, M.C., Pistikopoulos, E.N., A Novel Physiologically Based Compartmental Model for Volatile Anaesthesia, Computer Aided Chemical Engineering, 29, 2011, p1495-1499Journal Article, 2011, DOI
  • Pefani, E., Panoskaltsis, N., Mantalaris, A., Georgiadis, M.C., Pistikopoulos, E.N., Modelling and simulation of drug delivery systems for the treatment of acute myeloid leukemia, IFMBE Proceedings, 37, 2011, p259-262Journal Article, 2011, DOI
  • Lim, M., Panoskaltsis, N., Ye, H., Mantalaris, A., Optimization of in vitro erythropoiesis from CD34+ cord blood cells using design of experiments (DOE), Biochemical Engineering Journal, 55, (3), 2011, p154-161Journal Article, 2011, DOI
  • Zubairi, S., Bismarck, A., Koutinas, A., Panoskaltsis, N., Mantalaris, A., Surface treatment of poly(3-hydroxybutyric acid) (PHB) and poly(3-hydroxybutyric-co-3-hydroxyvaleric acid) (PHBV) porous 3-D scaffolds with an improved thickness to enhance cell-biomaterial adhesion and interactions, 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials, 2011Journal Article, 2011
  • Pefani, E., Panoskaltsis, N., Mantalaris, A., Georgiadis, M.C., Pistikopoulos, E., Towards a high-fidelity model for model based optimisation of drug delivery systems in acute myeloid leukemia, Computer Aided Chemical Engineering, 29, 2011, p1505-1509Journal Article, 2011, DOI
  • Panoskaltsis, N., Belanger, T.J., Liesveld, J.L., Abboud, C.N., Optimal cytokine stimulation for the enhanced generation of leukemic dendritic cells in short-term culture, Leukemia Research, 26, (2), 2002, p191-201Journal Article, 2002, DOI
  • Mantalaris, A., Panoskaltsis, N., Sakai, Y., Bourne, P., Chang, C., Messing, E.M., David Wu, J.H., Localization of androgen receptor expression in human bone marrow, Journal of Pathology, 193, (3), 2001, p361-366Journal Article, 2001, DOI
  • Liesveld, J.L., Rosell, K., Panoskaltsis, N., Belanger, T., Harbol, A., Abboud, C.N., Response of human CD34+ cells to CXC, CC, and CX3C chemokines: Implications for cell migration and activation, Journal of Hematotherapy and Stem Cell Research, 10, (5), 2001, p643-655Journal Article, 2001, DOI
  • Panoskaltsis, N., Knight, S.C., Reid, C.D.L., Differential cytokine profiles of leukaemic blasts and leukaemic dendritic cells: implications for immunotherapy, Blood, 96, (11 PART II), 2000Journal Article, 2000
  • Panoskaltsis, N., Derman, M.P., Perillo, I., Brennan, J.K., Erratum: Thrombotic thrombocytopenic purpura in pulmonary-renal syndromes (American Journal of Hematology (2000) 65 (50-55)), American Journal of Hematology, 65, (3), 2000, p267Journal Article, 2000, DOI
  • Panoskaltsis, N., Derman, M.P., Perillo, I., Brennan, J.K., Thrombotic thrombocytopenic purpura in pulmonary-renal syndromes, American Journal of Hematology, 65, (1), 2000, p50-55Journal Article, 2000, DOI
  • Panoskaltsis, N., Abboud, C.N., Human immunodeficiency virus and the hematopoietic repertoire: implications for gene therapy., Frontiers in bioscience : a journal and virtual library, 4, 1999Journal Article, 1999, DOI
  • Savvopoulos, S., Misener, R., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., A Personalized Framework for Dynamic Modeling of Disease Trajectories in Chronic Lymphocytic Leukemia, IEEE Transactions on Biomedical Engineering, 63, (11), 2016, p2396-2404Journal Article, 2016, DOI
  • Chaudhry, M.S., Gilmour, K.C., House, I.G., Layton, M., Panoskaltsis, N., Sohal, M., Trapani, J.A., Voskoboinik, I., Missense mutations in the perforin (PRF1) gene as a cause of hereditary cancer predisposition, OncoImmunology, 5, (7), 2016Journal Article, 2016, DOI
  • Kostoglou, M., Fuentes-Garí, M., García-Münzer, D., Georgiadis, M.C., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., A comprehensive mathematical analysis of a novel multistage population balance model for cell proliferation, Computers and Chemical Engineering, 91, 2016, p157-166Journal Article, 2016, DOI
  • Fuentes-Garí, M., Misener, R., García-Munzer, D., Velliou, E., Georgiadis, M.C., Kostoglou, M., Pistikopoulos, E.N., Panoskaltsis, N., Mantalaris, A., A mathematical model of subpopulation kinetics for the deconvolution of leukaemia heterogeneity, Journal of the Royal Society Interface, 12, (108), 2015Journal Article, 2015, DOI
  • Misener, R., Fuentes-Garí, M., Velliou, E.G., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Robust design and operation of red blood cell production in a parallelised hollow fibre bioreactor, Computing and Systems Technology Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting, 2, 2014, p803-805Journal Article, 2014
  • Misener, R., Chin, J., Lai, M., Fuentes Garí, M., Velliou, E., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Robust superstructure optimisation of a bioreactor that produces red blood cells, Computer Aided Chemical Engineering, 33, 2014, p91-96Journal Article, 2014, DOI
  • Krieger, A., Panoskaltsis, N., Mantalaris, A., Georgiadis, M.C., Pistikopoulos, E.N., Modeling and analysis of individualized pharmacokinetics and pharmacodynamics for volatile anesthesia, IEEE Transactions on Biomedical Engineering, 61, (1), 2014, p25-34Journal Article, 2014, DOI
  • Fauzi, I., Panoskaltsis, N., Mantalaris, A., Early exposure of murine embryonic stem cells to hematopoietic cytokines differentially directs definitive erythropoiesis and cardiomyogenesis in alginate hydrogel three-dimensional cultures, Stem Cells and Development, 23, (22), 2014, p2720-2729Journal Article, 2014, DOI
  • Savvopoulos, S., Misener, R., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., A personalized framework for dynamic modelling of chronic lymphocytic leukemia disease trajectories, Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting, 2, 2014, p999-1001Journal Article, 2014
  • Velliou, E., Fuentes-Garí, M., Misener, R., Pefani, E., Rende, M., Panoskaltsis, N., Mantalaris, A., Pistikopoulos, E.N., A framework for the design, modeling and optimization of biomedical systems, Computer Aided Chemical Engineering, 34, 2014, p225-236Journal Article, 2014, DOI
  • Misener, R., Fuentes Garí, M., Rende, M., Velliou, E., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A., Global superstructure optimisation of red blood cell production in a parallelised hollow fibre bioreactor, Computers and Chemical Engineering, 71, 2014, p532-553Journal Article, 2014, DOI
  • Placzek, M.R., Chung, I.-M., Macedo, H.M., Ismail, S., Blanco, T.M., Lim, M., Jae, M.C., Fauzi, I., Kang, Y., Yeo, D.C.L., Ma, C.Y.J., Polak, J.M., Panoskaltsis, N., Mantalaris, A., Stem cell bioprocessing: Fundamentals and principles, Journal of the Royal Society Interface, 6, (32), 2009, p209-232Journal Article, 2009, DOI
  • Yue, X., Drakakis, E.M., Lim, M., Radomska, A., Ye, H., Mantalaris, A., Panoskaltsis, N., Cass, A., A real-time multi-channel monitoring system for stem cell culture process, IEEE Transactions on Biomedical Circuits and Systems, 2, (2), 2008, p66-77Journal Article, 2008, DOI
  • Kumar, R., Panoskaltsis, N., Stepanek, F., Mantalaris, A., Coupled oxygen-carbon dioxide transport model for the human bone marrow, Food and Bioproducts Processing, 86, (3), 2008, p211-219Journal Article, 2008, DOI
  • Lim, M., Ye, H., Drakakis, E.M., Yue, X., Cass, A.E.G., Panoskaltsis, N., Mantalaris, A., Towards information-rich bioprocessing: Generation of spatio-temporal profiles through the use of design of experiments to determine optimal number and location of sensors-An example in thermal profiles, Biochemical Engineering Journal, 40, (1), 2008, p1-7Journal Article, 2008, DOI
  • Lim, M., Ye, H., Panoskaltsis, N., Mantalaris, A., Optimal expansion and differentiation of cord blood stem cells using design of experiments, Handbook of Cardiac Stem Cell Therapy, 2008, p265-281Journal Article, 2008
  • Xicai, Y., Drakakis, E.M., Hua, Y., Lim, M., Mantalaris, A., Panoskaltsis, N., Radomska, A., Toumazou, C., Cass, T., An on-line, multi-parametric, multi-channel physicochemical monitoring platform for stem cell culture bioprocessing, Proceedings - IEEE International Symposium on Circuits and Systems, 2007, p1215-1218Journal Article, 2007
  • Lim, M., Ye, H., Panoskaltsis, N., Drakakis, E.M., Yue, X., Cass, A.E.G., Radomska, A., Mantalaris, A., Intelligent bioprocessing for haemotopoietic cell cultures using monitoring and design of experiments, Biotechnology Advances, 25, (4), 2007, p353-368Journal Article, 2007, DOI
  • Ltesveld, J.L., Resell, K.E., Belanger, T.J., Harfaol, A.L., Panoskaltsis, N., Abboud, C.N., Effects of chemokfnes on cd34+ progenitors, Experimental Hematology, 26, (8), 1998, p729Journal Article, 1998
  • de Janon A, Mantalaris A, Panoskaltsis N., Three-Dimensional Human Bone Marrow Organoids for the Study and Application of Normal and Abnormal Hematoimmunopoiesis., Journal of immunology (Baltimore, Md. : 1950), 210, (7), 2023, p895-904Journal Article, 2023, DOI
  • Murnane C., Gardiner N., Crehan O., Bacon C.L., McHugh R., Gilmer J.F., Mantalaris A., Panoskaltsis N., Chimeric Antigen Receptor-T (CAR-T) Cells as " Living Drugs ": A Clinical Pharmacist Perspective, Journal of Clinical Pharmacy and Therapeutics, 2024, 2024Journal Article, 2024, DOI