Dr. Carlos Medina Martin

Associate Professor, Pharmacy

Biography

Dr. Carlos Medina was born in Tenerife, Spain. After studying Medicine at University of La Laguna, he specialized in Gastroenterology at Vall d'Hebron Hospital, Barcelona and was consultant gastroneterologist at Hospital Universitario de Canarias, Tenerife. He obtained his PhD in Medicine from the Universitat Autonoma de Barcelona in 2004 studying new molecular targets in different experimental models of colitis. He conducted post-doctoral studies funded by the Spanish Ministry of Science and Education (MECD/Fulbright)at the Institute of Molecular Medicine, Texas Medical Center, Houston, focused on platelet-tumour cell interactions under the supervision of Prof Radomski. In 2007 he was appointed as Science Foundation Ireland Stokes lecturer in Pharmacology, School of Pharmacy, TCD. Presently he leads a pharmacology research group which has been mainly supported by SFI and Enterprise Ireland. His research is primarily focused on: 1) pharmacological treatments for gastrointestinal diseases including liver; 2) platelet-tumour cell interactions and 3) nanomedicine. Dr Medina has published more than 60 scientific articles and contributed to more than 55 posters and presentations at national and international conferences.

Publications and Further Research Outputs

Peer-Reviewed Publications
Non-Peer-Reviewed Publications

Santos-Martinez, M.J., Tomaszewski, K., Medina, C., Bazou, D., Gilmer, J.F., Radomski, M.W. , Pharmacological characterization of nanoparticle-induced platelet microaggregation using quartz crystal microbalance with dissipation: comparison with light aggregometry, International Journal of Nanomedicine, 10, 2015, p5107 - 5119Journal Article, 2015, DOI , TARA - Full Text
Samuel S., Santos-Martinez M., Medina C., Jain N., Radomski MW., Prina-Mello A., Volkov Y., CdTe quantum dots induce activation of human platelets: Implications for nanoparticle hemocompatibility, International Journal of Nanomedicine, 10, 2015, p2723-2734Journal Article, 2015, DOI , TARA - Full Text
Umerska A, Paluch KJ, Santos-Martinez MJ, Medina C, Corrigan OI, Tajber L, Chondroitin-based nanoplexes as peptide delivery systems--Investigations into the self-assembly process, solid-state and extended release characteristics., European Journal of Pharmaceutics and Biopharmaceutics, 93, 2015, p242 - 253Journal Article, 2015, DOI , TARA - Full Text
O'Sullivan S, Wang J, Pigott MT, Docherty N, Boyle N, Lis SK, Gilmer JF, Medina C, Inhibition of matrix metalloproteinase-9 by a barbiturate-nitrate hybrid ameliorates dextran sulphate sodium-induced colitis: effect on inflammation-related genes, British Journal of Pharmacology, 174, (7), 2017, p512 - 524Journal Article, 2017, DOI
Abautret-Daly Á, Dempsey E, Riestra S, de Francisco-García R, Parra-Blanco A, Rodrigo L, Medina C, Connor TJ, Harkin A., Association between psychological measures with inflammatory and disease related markers of inflammatory bowel disease, International Journal of Psychiatry & Clinical Practice, 21, (3), 2017, p221 - 230Journal Article, 2017, DOI
Abautret-Daly Á, Dempsey E, Riestra S, de Francisco-García R, Parra-Blanco A, Rodrigo L, Medina C, Connor TJ, Harkin A., Gut-brain actions underlying comorbid anxiety and depression associated with inflammatory bowel disease, Acta Neuropsychiatr, 2017, p1 - 22Review Article, 2017, DOI
Pharmacological significance of nanoparticles in, editor(s)Klaus D Sattler , Handbook of Nanophysics, CRC Press, 2010, [C Medina, MW Radomski]Book Chapter, 2010
Antithrombotic agents in, editor(s)Ignacio Lizasoain, MA Moro , Velazquez. Farmacologica clinica y basica, 2017, [MJ Santos-Martinez, MW Radomski, C Medina]Book Chapter, 2017
B Hall, G Holleran, S O'Sullivan, S Smith, B Ryan, C Medina, D McNamara, Crohn's disease in an Irish population-A genotype-phenotype analysis, Journal of Crohn's and Colitis, 9th ECCO Conference, Denmark, 8, (S1), 2014, ppS345-Meeting Abstract, 2014, DOI
S. Paul-Samuels, MJ Santos-Martinez, C Medina, N Jain, MW Radomski, A Prina-Mello, Y Volkov, . CdTe qunatum dots induce activation of human platelets. , American Journal of Medicine, Amerian Physician Scientists Association, Chicago, USA, , April 2013, 2013Conference Paper, 2013
A. Abautret-Daly, C. Medina, T.J. Connor, A. Harkin, Altered peripheral, circulating and central tryptophan concentrations in the DSS model of colitis., Proceedings of Neuroscience Ireland , 7th Annual Meeting of Neuroscience Ireland, Dublin, September, 2012., 2012Conference Paper, 2012
A. Abautret-Daly, N Murphy, N Docherty, C. Medina, T.J. Connor, A. Harkin, Behavioural changes in the DSS model of colitis are associated with long-term systematic anc central induction of iNOS in rats, Proceedings of Neuroscience Ireland, 7th Annual Meeting Neuroscience Ireland, 2012Conference Paper, 2012
A Abautret-Daly, C Medina, TJ Connor, A Harkin, Evidence of depression and anxiety related behavioural disturbances associated with activation of the kyneurine pathway and expression of hepatic tryptophan 2,3 dioxygenase in animal models of IBD., Brain, Behaviour and Immunity, FENS Forum, Amsterdam, July 2010, 2010Conference Paper, 2010
A Abautret-Daly, C Medina, TJ Connor, A Harkin, Behavioural disturbances observed in experimental colitis are associated with activation of the kyneurine pathway and expression of hepatic tryptophan 2,3 dioxygenase, Brain, Behaviour and Immunity, 17th Annual Meeting of The PsychoNeuroImmunology Research Society, Dublin, June 2010, 2010, ppS50Conference Paper, 2010
A Abautret-Daly, C Medina, TJ Connor, A Harkin, Anxiety related behaviour in an animal model of experimental colitis is associated with a long-term systemic and central inflammatory response, Brain, Behaviour and Immunity, 17th Annual Meeting of The PsychoNeuroImmunology Research Society, Dublin, 24, 2010, ppS55Conference Paper, 2010
A Abautret-Daly, C Medina, TJ Connor, A Harkin, Evidence of depression and anxiety related behavioural disturbances associated with the activation of the kyneurine pathway and expression of hepatic tryptophan 2,3 dioxygenase in an animal model of IBD, Brain, Behaviour and Immunity, Drugs & the brain workshops, Braga, 2010, 2010Conference Paper, 2010
E Dempsey, A Abautret-Daly, J Downing, A Harkin, C Medina, Evidence for central molecular changes and changes to neuronal activity in an animal model of inflammatory bowel disease, European Neuropsychopharmacology, 2015, 25, 2015, ppS233-S234Conference Paper, 2015
Dempsey, E., Abautret-Daly, A., Medina, C., Docherty, N., Harkin A., Central neuroinflammation in inflammatory bowel disease: evidence for a central increase in iNOS in an animal model of colitis, European Neuropsychopharmacology, ECNP Workshop for Junior Scientists in Europe , Nice, France, 2015, 25, 2015, ppS47-S47Poster, 2015
A Radziwon, C Medina, L O'Driscoll, MW Radomski, Platelets inhibit drug chemotherapy-induced cancer cell apoptosis, 7th International Cancer Conference, Dublin, 2009Conference Paper, 2009
L Bouissane, MP Cabildo, MP Cornago, RM Claramunt, J Elguero, C. Medina, Synthesis and biological evaluation of curcuminum pyrazoles as nex therapeutic agents in IBD, Bioorganic Medicinal Chemistry, Tetrahedron Symposium, Challenges in Organic & Bioorganic Chemistry., San Diego, USA, 2008Conference Paper, 2008
M Menacho, Y Barrios, MC Paz-Cabrera, C Medina, A Pardo, E Salido, E Quintero, Inflammatory bowel disease and homocystinuria., Gastroenterologia Hepatologia, IX Spanish Gastroenterology Association, Madrid, 2006Conference Paper, 2006
AZ Gimeno-García, C Paz-Cabrera, E Salido, C Medina, A Jiménez, A Santana, A Parra-Blanco, D Nicolás, E Quintero, UP-regulation of MMP-9 in familiar adenomatous polyposis, Gastroenterologia Hepatologia, IX Spanish Gastroenterology Association, Madrid, 2006Conference Paper, 2006
A Santana, C Medina, MC Paz Cabrera, F Diaz-Gonzalez, E Ferre, A Salas, MW Radomski, E Quintero. , Deletion of MMP-9 attenuates intestinal injury in DSS-induced colitis, Gastroenterologia Hepatologia, VIII Spanish Gastroenterology Association, Madrid, 2005Conference Paper, 2005
A Santana, C Medina, MC Paz-Cabrera, F Diaz-Gonzalez, E Ferre, A Salas, MW Radomski, E Quintero, Deletion of MMP-9 attenuates intestinal injury in DSS-induced colitis, Gastroenterology, American Gastroentorolgy Asociation, Chicago, USA,, 2005Conference Paper, 2005
C Medina, A Santana, MC Paz-Cabrera, F Diaz-Gonzalez, E Quintero, UP-regulation of MMP-9 in a rat model of experimental colitis, Gastroenterologia Hepatologia, VII Spanish Gastroenterology Association, Madrid, 2004Conference Paper, 2004
AZ Gimeno-García, A Santana, A Parra-Blanco, C Medina, D Nicolás-Pérez, MC Paz-Cabrera, F Díaz-Gonzalez, A Jiménez, L Díaz-Flores, E Quintero, UP-regulation of MMP-9 in adenomatous polyposis., Gastroenterologia Hepatologia, VII Spanish Gastroenterology Association, Madrid, 2004Conference Paper, 2004
F Casellas, JI Arenas, S Baudet, S Fabregas, N Garcia, J Galabert, C Medina, I Otxotorena, M Papo, L Rodrigo, JR Malagelada, Quality of life in inflammatory bowel disease: Spanish study, Gastroenterologia Hepatologia, LVIII Spanish Congress of Digestive Diseases, Valencia, 2004Conference Paper, 2004
C Medina, A Santana, MC Paz-Cabrera, F Diaz-Gonzalez, E Quintero. , UP-regulation of MMP-9 in a rat model of experimental colitis, Gastroenterology, American Gastroentorolgy Asociation, New Orleans, 2004Conference Paper, 2004
AZ Gimeno-García, A Santana, A Parra-Blanco, C Medina, D Nicolás-Pérez, MC Paz-Cabrera, F Díaz-Gonzalez, A Jiménez, L Díaz-Flores, E Quintero, UP-regulation of MMP-9 in adenomatous polyposis., Gastroenterology, American Gastroentorolgy Asociation, New Orleans, 2004Conference Paper, 2004
C. Medina, M. Llopis, M. Antolín, S. Videla, F. Guarner, J. Vilaseca, R. Freire, A. Salas, E. Quintero, JR Malagelada, Implication of MMPs in transmural inflammation induced by bacteroides fragilis, Gastroenterologia Hepatologia, XII Catalan Gastroenterology Association., Lleida, Spain, 2003Conference Paper, 2003
. Medina, Y. Barrios, M-C. Paz-Cabrera, M. Menacho, J-A Ortega-Sanchez, A. Jiménez, E. Salido, E. Quintero, Implication of MMP-9 genetic polymorphism on Crohn's disease behaviour, Gastroenterologia Hepatologia, XII Catalan Gastroenterology Association., Lleida, Spain, 2003Conference Paper, 2003
C. Medina, M. Llopis, M. Antolín, S. Videla, F. Guarner, J. Vilaseca, R. Freire, A. Salas, E. Quintero, JR Malagelada, Implication of MMPs in transmural inflammation induced by bacteroides fragilis, Gastroenterologia Hepatologia, VI Spanish Gastroenterology Association., Madrid, 2003Conference Paper, 2003
Gimeno, A. Parra, C. García, D. Nicolás, C. Medina, L. Diaz-Flores, E. Quintero, Prevalence of high grade dysplasia in flat adenomas., European Journal of Gastroenterology, Association of National European and Mediterranean Societies of Gastroenterology, Madrid, 2003Conference Paper, 2003
C. Medina, M. Llopis, M. Antolín, S. Videla, F. Guarner, J. Vilaseca, R. Freire, C. I. Gonzalez, A. Salas, E. Quintero, J-R Malagelada, Implication of MMPs in transmural inflammation induced by bacteroides fragilis, Gastroenterology, American Gastroenterolgy Association, Orlando, USA, 2003Conference Paper, 2003
C. Medina, Y. Barrios, M-C. Paz-Cabrera, M. Menacho, J-A Ortega-Sanchez, A. Jiménez, E. Salido, E. Quintero, Implication of MMP-9 genetic polymorphism on Crohn's disease behaviour, Gastroenterologia Hepatologia, VI Spanish Gastroenterology Association., Madrid, 2003Conference Paper, 2003
Gimeno, A. Parra, C. García, D. Nicolás, C. Medina, L. Diaz-Flores, E. Quintero, Prevalence of high grade dysplasia in flat adenomas., Gastroenterologia Hepatologia, VI Spanish Gastroenterology Association., Madrid, 2003Conference Paper, 2003
M Antolín, C Medina, A García-Lafuente, S Videla, F Guarner, J Vilaseca, A Salas, JR Malagelada, Anti-inflammatory effect of lactobacillus in DSS-induced colitis, Gastroenterologia Hepatologia, XI Catalan Gastroenterology Association, Reus, Spain, 2002Conference Paper, 2002
M Antolín, C Medina, A García-Lafuente, S Videla, F Guarner, J Vilaseca, A Salas, JR Malagelada, Anti-inflammatory effect of lactobacillus in DSS-induced colitis, Gastroenterologia Hepatologia, V Spanish Gastroenterology Association, Madrid, 2002Conference Paper, 2002
C Medina, S Videla, A Radomski, MW Radomski, M Antolín, F Guarner, J Vilaseca, A Salas, JR Malagelada, UP-regulation of MMP-9 in an experimental model of ulcerative colitis, Gastroenterologia Hepatologia, X Catalan Gastroenterology Association., Lloret de Mar, Spain, 2001Conference Paper, 2001
C Medina, R Fabra, J Vilaseca, JR Armengol, JR Malagelada, Clinical characteristics of patients with ischaemic colitis, Gastroenterologia Hepatologia, X Catalan Gastroenterology Association., Lloret de Mar, Spain, 2001Conference Paper, 2001
C Medina, S Videla, A Radomski, MW Radomski, M Antolín, F Guarner, J Vilaseca, A Salas, JR Malagelada, UP-regulation of MMP-9 in an experimental model of ulcerative colitis, Gastroenterologia Hepatologia, IV Spanish Gastroenterology Association, Madrid, 2001Conference Paper, 2001
C Medina, S Videla, MW Radomski, M Antolín, F Guarner, J Vilaseca, A Salas, JR Malagelada, Inhibition of MMPs prevents tissue injury and fibrotic complications in two rat models of IBD, Gastroenterologia Hepatologia, IX Catalan Gastroenterology Association, Tortosa, Spain, 2000Conference Paper, 2000
C Medina, S Videla, MW Radomski, M Antolín, F Guarner, J Vilaseca, A Salas, JR Malagelada, Inhibition of MMPs prevents tissue injury and fibrotic complications in two rat models of IBD, Gastroenterology, American Gastroentorolgy Asociation, San Diego, USA, 2000Conference Paper, 2000
S Videla, C Medina, M Antolín, F Guarner, J Vilaseca, A Salas, JR Malagelada, Butiric acid enema prevents inflammation in DSS-induced colitis, Gastroenterologia Hepatologia, IX Catalan Gastroenterology Association, Tortosa, Spain, 2000Conference Paper, 2000
C Medina, R Fabra, J Vilaseca, JR Armengol, JR Malagelada, Clinical characteristics of pateients with ischaemic colitis, Gastroenterologia Hepatologia, XXVII Spanish Congress of Digestive Diseases, La Corunya, Spain, 2000Conference Paper, 2000
C Medina, M Vergara, F Casellas, J Naval, F Lara, JR Malagelada, Patient assessment of the long-term benefits of surgery in IBD, Gastroenterologia Hepatologia, XXV Spanish Society for Digestive Diseases, Oviedo, Spain, 1998Conference Paper, 1998
C Medina, M Vergara, F Casellas, J Naval, F Lara, JR Malagelada, Effects of smoking habit in the surgery of IBD, Gastroenterologia Hepatologia, VI Catalan Gastroenterology Association, Andorra, 1997Conference Paper, 1997
F Casellas, X Fraga, M Vergara, C Medina, Bermejo, JR Malagelada, Effects of smoking on the presentation and clinical course of IBD, Gastroenterologia Hepatologia, XXIV Spanish Society for Digestive Diseases, Sevilla, Spain, 1997Conference Paper, 1997
X Fraga, M Vergara, C Medina, F Casellas, Bermejo, JR Malagelada, Effects of smoking on the presentation and clinical course of IBD, Gastroenterologia Hepatologia, V Catalan Gastroenterology Association, Gerona, Spain, 1997Conference Paper, 1997
J Gilmer, M Ledwige, P O'Flynn, S Harmon, MW Radomski, C Medina, 'Compounds with super-aspirin effects', European Patent Office, 20 January 2012Patent, URL
Abautret-Daly, Ã ., Dempsey, E., Parra-Blanco, A., Medina, C., Harkin, A., Gut brain actions underlying comorbid anxiety and depression associated with inflammatory bowel disease, Acta Neuropsychiatrica, 2017, p1-22Journal Article, 2017, DOI , URL
Inkielewicz-Stepniak, I. and Tajber, L. and Behan, G. and Zhang, H. and Radomski, M.W. and Medina, C. and Santos-Martinez, M.J., The role of mucin in the toxicological impact of polystyrene nanoparticles, Materials, 11, (5), 2018, p724-Journal Article, 2018, DOI , URL , TARA - Full Text
Gebe, J.A. and Yadava, K. and Ruppert, S.M. and Marshall, P. and Hill, P. and Falk, B.A. and Sweere, J.M. and Han, H. and Kaber, G. and Medina, C. and Mikecz, K. and Ziegler, S.F. and Balaji, S. and Keswani, S.G. and De Jesus Perez, V.A. and Butte, M.J. and Nadeau, K. and Altemeier, W.A. and Fanger, N. and Bollyky, P.L., Modified high-molecular-weight hyaluronan promotes allergen-specific immune tolerance, American Journal of Respiratory Cell and Molecular Biology, 56, (1), 2017, p109-120Journal Article, 2017, DOI , URL
Umerska A, Paluch KJ, Santos-Martinez MJ, Corrigan OI, Medina C, Tajber L, Freeze Drying of Polyelectrolyte Complex Nanoparticles: Effect of NP Composition and Cryoprotectant Selection, International Journal of Pharmaceutics, 552, 2018, p27 - 38Journal Article, 2018
Dempsey E, Abautret-Daly Á, Docherty NG, Medina C, Harkin A. , Persistent Central Inflammation and Region Specific Cellular Activation Accompany Depression- and Anxiety-like Behaviours During the Resolution Phase of Experimental Colitis, Brain Behav Immun , 80, 2019, p616-632Journal Article, 2019, DOI
Echegaray, J.J. and Medina, C.A. and Biscotti, C.V. and Plesec, T. and Singh, A.D., Multifocal Primary Uveal Melanoma: Clinical and Molecular Characteristics, Ocular Oncology and Pathology, 5, (1), 2019, p8-12Journal Article, 2019, DOI , URL
Hante NK, Medina C, Santos-Martinez MJ., Effect on Platelet Function of Metal-Based Nanoparticles Developed for Medical Applications., Frontiers in cardiovascular medicine., (6), 2019, p139-Journal Article, 2019, URL , TARA - Full Text
Garoon, R.B. and Medina, C.A. and Scelfo, C. and Harbour, J.W., RETINOCYTOMA WITH VITREOUS SEEDING: NEW INSIGHTS FROM ENHANCED DEPTH IMAGING OPTICAL COHERENCE TOMOGRAPHY AND HIGH-RESOLUTION POSTERIOR SEGMENT ULTRASONOGRAPHY, Retinal cases & brief reports, 15, (1), 2021, p68-70Journal Article, 2021, DOI , URL
Quilty F, Byrne AM, Aird J, El Mashad S, Parra-Blanco A, Long A, Gilmer JF, Medina C., Impact of Deoxycholic Acid on Oesophageal Adenocarcinoma Invasion: Effect on Matrix Metalloproteinases., International journal of molecular sciences, 21, (21), 2020Journal Article, 2020, DOI
Oâ sullivan, S. and Wang, J. and Radomski, M.W. and Gilmer, J.F. and Medina, C., Novel barbiturate-nitrate compounds inhibit the upregulation of matrix metalloproteinase-9 gene expression in intestinal inflammation through a CGMP-mediated pathway, Biomolecules, 10, (5), 2020Journal Article, 2020, DOI , URL
Fahmy, U.A. and Ahmed, O.A.A. and Badr-Eldin, S.M. and Aldawsari, H.M. and Okbazghi, S.Z. and Awan, Z.A. and Bakhrebah, M.A. and Alomary, M.N. and Abdulaal, W.H. and Medina, C. and Alhakamy, N.A., Optimized nanostructured lipid carriers integrated into in situ nasal gel for enhancing brain delivery of flibanserin, International Journal of Nanomedicine, 15, 2020, p5253-5264Journal Article, 2020, DOI , URL
Wang, J. and Medina, C. and Radomski, M.W. and Gilmer, J.F., N-Substituted homopiperazine barbiturates as gelatinase inhibitors, Bioorganic and Medicinal Chemistry, 19, (16), 2011, p4985-4999Journal Article, 2011, DOI , URL
Buckley, S.T. and Medina, C. and Kasper, M. and Ehrhardt, C., Interplay between RAGE, CD44, and focal adhesion molecules in epithelial-mesenchymal transition of alveolar epithelial cells, American Journal of Physiology - Lung Cellular and Molecular Physiology, 300, (4), 2011, pL548-L559Journal Article, 2011, DOI , URL
Videla, S. and Lugea, A. and Vilaseca, J. and Guarner, F. and Treserra, F. and Salas, A. and Crespo, E. and Medina, C. and Malagelada, J.R., Polyethylene glycol enhances colonic barrier function and ameliorates experimental colitis in rats, International Journal of Colorectal Disease, 22, (6), 2007, p571-580Journal Article, 2007, DOI , URL
Videla, S. and Vilaseca, J. and Medina, C. and Mourelle, M. and Guarner, F. and Salas, A. and Malagelada, J.-R., Modulatory effect of nitric oxide on mast cells during induction of dextran sulfate sodium colitis, Digestive Diseases and Sciences, 52, (1), 2007, p45-51Journal Article, 2007, DOI , URL
Gimeno-GarcÃa, A.Z. and Santana-RodrÃguez, A. and JimÃ©nez, A. and Parra-Blanco, A. and NicolÃ¡s-PÃ©rez, D. and Paz-Cabrera, C. and DÃaz-GonzÃ¡lez, F. and Medina, C. and DÃaz-Flores, L. and Quintero, E., Up-regulation of gelatinases in the colorectal adenoma-carcinoma sequence, European Journal of Cancer, 42, (18), 2006, p3246-3252Journal Article, 2006, DOI , URL
Santana, A. and Medina, C. and Paz-Cabrera, M.C. and DÃaz-Gonzalez, F. and FarrÃ©, E. and Salas, A. and Radomski, M.W. and Quintero, E., Attenuation of dextran sodium sulphate induced colitis in matrix metalloproteinase-9 deficient mice, World Journal of Gastroenterology, 12, (40), 2006, p6464-6472Journal Article, 2006, DOI , URL
O'Connor, Melanophy G, Medina C, Flattery M, O'Dea E, Transition to ePrescribing for systemic anti-cancer therapy " Perceptions of a multidisciplinary haematology/oncology team in a large teaching hospital, Journal of Oncology Pharmacy Practice, 10781552221126102, 2022Journal Article, 2022
S Videla, A Lugea, J Vilaseca, F Guarner, F Treserra, A Salas, E Crespo, C Medina, JR Malagelada, PEG Enhances Colonic Barrier Function and Ameliorates Experimental Colitis in Rats, International Journal of Colorectal Disease, 22, 2007, p571 - 580Journal Article, 2007
A Parra-Blanco, AZ Gimeno-García, D Nicolás- Pérez, C García, C Medina, L Díaz-Flores, B Grosso, A Jiménez, E Quintero, Risk for High-Grade Dysplasia or Invasive Carcinoma in Colorectal Flat Adenomas, Gastroenterol Hepatol, 29, 2006, p602 - 609Journal Article, 2006
A Santana, C Medina, MC Paz, F Díaz, E Farre, A Salas, MW Radomski, E Quintero, Attenuation of DSS-Induced Colitis in MMP-9 Deficient Mice, World Journal of Gastroenterology, 12, 2006, p6464 - 6472Journal Article, 2006
C Medina, A Santana, MC Paz-Cabrera, A Parra-Blanco, D Nicolas-Perez, Z Gimeno-Garcia, E Quintero, Increased Activity and Expression of Gelatinases in Ischemic Colitis, Digestive Diseases and Sciences, 51, 2006, p2393 - 2399Journal Article, 2006
S Videla, J Vilaseca, C Medina, M Mourelle, F Guarner, A Salas, J-R Malagelada, Modulatory Effect of NO on Mast Cells in DSS-Induced Colitis, Digestive Diseases and Sciences, 52, 2007, p45 - 51Journal Article, 2007
AZ Gimeno-García, A Santana, A Jiménez, A Parra-Blanco, D Nicolás-Pérez, C Paz-Cabrera, F Díaz-González, C Medina, L Díaz-Flores, E Quintero, UP-Regulation of Gelatinases in the Colorectal Adenoma-Carcinoma Sequence, European Journal of Cancer, Sept 12, 2006, pEpub ahead-Journal Article, 2006
D Alonso-Escolano, C Medina, K Cieslik, A Radomski, P Jurasz, MJ Santos-Martinez, P Ruvolo, MW Radomski, PKCä Mediates Platelet-Induced Breast Cancer Cell Invasion, Journal of Pharmacology Experimental therapeutics, 318, 2006, p373 - 380Journal Article, 2006, TARA - Full Text
S Videla, J Vilaseca, C Medina, M Mourelle, F Guarner, A Salas, J-R Malagelada, Phosphodiesterase-IV Inhibition Prevents Chronic Colitis and Intestinal Fibrosis, Journal of Pharmacology Experimental Therapeutics , 316, 2006, p940 - 945Journal Article, 2006
F Casellas, JI Arenas, S Baudet, S Fábregas, N García, J Gelabert, C Medina, I Ochotorena, M Papo, L Rodrigo, J-R Malagelada, Impairement of Health Related Quality of Life in Patients with Inflammatory Bowel Disease. A Spanish Multicenter Study., Inflammatory Bowel Disease , 11, 2005, p488 - 496Journal Article, 2005
C Medina, A Santana, M LLopis, MC Paz-Cabrera, M Antolin, F Guarner, J Vilaseca, M Mourelle, C Gonzalez, A Salas, E Quintero, JR Malagelada, Transmural Colonic Inflammation Induced by Bacteroides Fragilis: Implication of Matrix Metalloproteinases, Inflammatory Bowel Disease, 11 , 2005, p99 - 105Journal Article, 2005
AZ Gimeno, A Parra-Blanco, J Ortega, D Nicolás, C Medina, E Quintero, Colonic Dieulafoy Lesions Treated Endoscopically with Hemoclips, Diseases of Colon and Rectum, 47 , 2004, p1539 - 1943Journal Article, 2004
C Medina, J Vilaseca, S Videla, R Fabra, JR Armengol-Miró, JR Malagelada, Outcome of Patients with Ischemic Colitis: Review of Fifty Three Cases, Diseases of Colon and Rectum, 47 , 2004, p180 - 184Journal Article, 2004
S Baudet, C Medina, J Andreu, J Vilaseca, JR Malagelada, Effect of Short-Term Octreotide Therapy and Total Parenteral Nutrition on Development of Biliary Sludge or Lithiasis, Hepatogastroenterology, 62 , 2002, p609 - 612Journal Article, 2002
C Medina, T Molins, L Guarner, JR Malagelada, Cerebrovascular Accident as the Form of Presentation of a Pancreatic Cystadenocarcinoma: an Unusual Form of Presentation in a Rare Tumor, Gastroenterol Hepatol, 23, 2000, p132 - 134Journal Article, 2000
E Arcos, C Medina, F Mearin, J Larish, L Guarner, JR Malagelada, Achalasia Presenting as Acute Airway Obstruction, Digestive Diseases and Sciences, 10, 2000, p2079 - 2083Journal Article, 2000
C Medina, M Vergara, F Casellas, J Naval, F Lara, JR Malagelada, Patient Assessment of the Long-Term Benefits of Surgery in Inflammatory Bowel Disease, Rev Clin Esp , 200, 2000, p470 - 474Journal Article, 2000
C Medina, M Vergara, F Casellas, J Naval, F Lara, JR Malagelada, Influence of the Smoking Habit in the Surgery of Inflammatory Bowel Disease, Rev Esp Enf Dig , 90, 1998, p771 - 774Journal Article, 1998
X Fernández, M Vergara, C Medina, F Casellas, L Bermejo, J-R Malagelada, Effects of smoking on the presentation and clinical course of inflammatory bowel disease , European Journal of Gastroenterology and Hepatology , 9, (7), 1997, p683 - 687Journal Article, 1997
JS Baudet, JR Armengol, C Medina, A Accarino, J Vilaseca, JR Malagelada, Percutaneous endoscopic gastrostomy as a treatment for chronic gastric, Endoscopy , 29, (2), 1997, p147 - 148Journal Article, 1997, DOI
C Medina, A Santana, E Quintero, MW Radomski, F Guarner, Matrix Metalloproteinases in Gastrointestinal Disorders, Gastroenterol Hepatol , 27, 2004, p491 - 497Review Article, 2004
Santos-Martínez MJ, Medina C, Jurasz P, Radomski MW., Role of metalloproteinases in platelet function, Thrombosis Research, 121, 2008, p535 - 542Review Article, 2008
Santos-Martinez MJ, Medina C, Gilmer JF, Radomski MW., Matrix metalloproteinases in platelet function: coming of age, Journal of Thrombosis and Haemostasis, 6, (3), 2008, p514 - 516Review Article, 2008, DOI
Medina, C., Videla, S., Radomski, A., Radomski, M., Antolin, F., Guarner, F., Vilaseca, J., Salas, A., Malagelada, J.R, Therapeutic effect of phenanthroline in two rat models of inflammatory bowel disease. , Scandinavian Journal of Gastroenterology, 36, 2001, p1314 - 1319Journal Article, 2001
Medina, C., Videla, S., Radomski, A., Radomski M.W., Antolin, M., Guarner, F., Vilaseca, J., Salas, A., Malagelada, J.R. , Increased activity and expression of matrix metaloproteinase-9 in a rat model of distal colitis. , American Journal of Physiology, 284, (1), 2003, pG116 - G122Journal Article, 2003, DOI , URL
Medina, C., Santana, A., Paz, M.C., Diaz, F., Farre, E., Salas, A., Radomski, M.W., Quintero, E., Matrix metalloproteinase-9 modulates intestinal injury in rats with transmural colitis. , Journal of Leukocyte Biology, 79, 2006, p954 - 962Journal Article, 2006, DOI , URL , TARA - Full Text
Medina, C., Jurasz, P., Santos-Martinez, M.J., Jeong, S.S., Mitzky, R., Chen, R., Radomski, M.W. , Platelet aggregation induced by Caco-2 cells: regulation by matrix metalloproteinase-2 and adenosine diphosphate, Journal of Pharmacology and Experimental Therapeutics, 317, (2), 2006, p739 - 745Journal Article, 2006, DOI , URL , TARA - Full Text
Alonso-Escolano, D., Medina, C., Cieslik, K., Radomski, A., Jurasz, P., Santos-Martinez, M.J., Jiffar, T., Ruvolo, P., Radomski, M.W, Protein Kinase C{delta} Mediates Platelet-Induced Breast Cancer Cell Invasion, Journal of Pharmacology and Experimental Therapeutics, 318, 2006, p372 - 380Journal Article, 2006, DOI , URL
Medina, C., Radomski, M.W, Role of Matrix Metalloproteinases in Intestinal Inflammation, Journal of Pharmacology and Experimental Therapeutics, 318, (3), 2006, p933-938Review Article, 2006, DOI , URL , TARA - Full Text
Medina, C., Santos-Martinez, M.J., Radomski, A., Corrigan, O.I., Radomski, M.W., Nanoparticles: pharmacological and toxicological significance, British Journal of Pharmacology, 150, 2007Review Article, 2007, DOI , URL , TARA - Full Text
Medina, C., Gilmer, J. and Radomski, M.W., Matrix metalloproteinase-9 (MMP-9) as a therapeutic target for treatment of inflammatory bowel disease, Norgine, Harefield, U.K, 14 April 2008, 2008, Dr. M. FarrellInvited Talk, 2008
RM Claramunt, L. Bouissane, MP Cabildo, MP Cornago, J Elguero, A Radziwon, C Medina, Synthesis and biological evaluation of curcuminoid pyrazoles as new therapeutic agents in inflammatory bowel disease: effect on matrix metalloproteinases., Bioorganic & Medicinal Chemistry, 17, (3), 2009, p1290-1296Journal Article, 2009, DOI
Gilmer JF, Inkielewicz I, Jones M, Radomski A, Medina C, Santos Martinez MW, Radomski MW, Clancy JM, In vitro activation and platelet inhibition effects of the first true aspirin and nitro-aspirin prodrugs, Bioorganic Medicinal Chemistry, IBC's 13th Annual World Congress " Drug Discovery and Development of Innovative Therapeutics" August 4-7th 2008. , 2008Conference Paper, 2008
Radziwon A, O'Dwyer R, Medina C, Radomski MW., Inhibition of platelet-stimulated matrix metalloproteinase-9 generation in Caco-2 cells by selective MAP kinase inhibitors., 6TH International Cancer Conference, St. James's Hospital in Dublin., 2008Conference Paper, 2008
ST Buckley, C Medina, C Ehrhardt, Effect of TGF-β1 and inflammatory cytokines on EMT and cell migration in alveolar epithelial cells, Acta Physiol , 88th Annual Meeting of the German Physiological Society, Giessen, Germany, 22-25/03/2009, 195, (S669), 2009, pp14Conference Paper, 2009
ST Buckley, C Medina, C Ehrhardt, Characterisation of the role of inflammatory cytokines in EMT and cell migration in alveolar epithelial cells, FASEB J, Experimental Biology Meeting 2009, New Orleans, LA, 18-22/04/2009, 23, 2009, pp997.2Conference Paper, 2009
ST Buckley, C Medina, C Ehrhardt, Characterisation of the role of inflammatory cytokines in EMT and cell migration in alveolar epithelial cells, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2009, San Diego, CA, 15-20/05/2009, 179, (1), 2009, ppA5298Conference Paper, 2009
ST Buckley, C Medina, C Ehrhardt, Assessment of the role of inflammatory cytokines in EMT and cell migration in alveolar epithelial cells, Eur Respir J, European Respiratory Society Annual Congress 2009, Wien, Austria, 12-16/09/2009, 22, (S53), 2009, pp582Conference Paper, 2009
Xue L, Radomski A, Corrigan OI, Tajber L, de Souza Menezes F, Endter S, Medina C, Radomski M, Platelet compatibility of PLGA, chitosan and PLGA-chitosan nanoparticles, Nanomedicine, 4, (7), 2009, p735 - 746Journal Article, 2009, DOI
Li, X., Radomski, A., Corrigan, O.I., Tajber, L., De Sousa Menezes, F., Endter, S., Medina, C., Radomski, M.W. , The Platelet Compatibility of Poly(lactide-co-glycolide) (PLGA), Chitosan and PLGA- Chitosan Nanoparticles, Nanomedicine, 4, 2009, p735 - 746Journal Article, 2009, URL
Jones, M., Inkielewicz, I., Medina, C., Santos-Martinzez, M.J., Radomski, M.W., Radomski, A., Lally, M.N., Moriarty, L.M., Gaynor, J., Carolan, C.G., Coyne, D., O'Byrne, P., Clancy, J.M., Gilmer, J.F. , Isosorbide-based aspirin prodrugs: integration of nitric oxide releasing groups. , Journal of Medicinal Chemistry, 52, (21), 2009, p6588-6598Journal Article, 2009, DOI
ST Buckley, C Medina, C Ehrhardt, The role of the receptor for advanced glycation end products (RAGE) in epithelial-mesenchymal transition in the lung: a potential therapeutic target, AAPS J, 23rd Annual Meeting of the AAPS, Los Angeles, CA, 08-12/11/2009, 11, (S2), 2009, ppW5006Conference Paper, 2009
ST Buckley, C Medina, C Ehrhardt, Investigations into the role of RAGE and ERM proteins in EMT of human alveolar epithelial cells, Acta Physiologica, Joint Meeting of the Scandinavian and German Physiological Societies, København, Denmark, 27-30/3/2010, 198, (S677), 2010, pp146 - 147Conference Paper, 2010
ST Buckley, C Medina, C Ehrhardt, RAGE and ERM proteins in EMT of human alveolar epithelial cells, FASEB J, Experimental Biology Meeting 2010, Anaheim, CA, 24-28/04/2010, 24, 2010, pp612.21Conference Paper, 2010
ST Buckley, C Medina, C Ehrhardt, A role for RAGE and ERM proteins in EMT of human alveolar epithelial cells, Am J Respir Crit Care Med , Annual Meeting of the American Thoracic Society 2010, New Orleans, LA, 14-19/05/2010, 181, (1), 2010, ppA1234Conference Paper, 2010
ST Buckley, C Medina, C Ehrhardt, Differential susceptibility to epithelial-mesenchymal transition (EMT) of alveolar, bronchial and intestinal epithelial cells in vitro and the effect of angiotensin II receptor inhibition, Cell Tissue Res, 342, (1), 2010, p39-51Journal Article, 2010, DOI
ST Buckley, C Medina, M Kasper, C Ehrhardt, Interplay between the receptor for advanced glycation end-products (RAGE), CD44 and focal adhesion molecules in epithelial-mesenchymal transition of alveolar epithelial cells, Am J Physiol Lung Cell Mol Physiol, 300, (4), 2011, pL548-L559Journal Article, 2011, DOI , TARA - Full Text
Santos-Martinez, MJ, Medina, C, Prina-Mello, A, Conroy, J, Samuels, SP, Volkov, Y, Radomski, MW, A nanoscale resolution assay of flow-induced platelet microaggregation, Kardiochirurgia i Torakochirurgia Polska, 7, (4), 2010, p365-375Journal Article, 2010, URL
Bazou D, Santos-Martinez MJ, Medina C, radomski MW, Elucidation of flow-mediated tumour cell-induced platelet aggregation using an ultrasound standing wave trap, British journal of Pharmacology, 162, (7), 2011, p1577 - 1589Journal Article, 2011, DOI
C Ehrhardt, C Medina, ST Buckley, Interaction of RAGE with focal adhesion molecules during alveolar epithelial-mesenchymal transition, FASEB J, Experimental Biology Meeting 2011, Washington, DC, 09-13/04/2011, 25, 2011, pp865.1Conference Paper, 2011
C Ehrhardt, C Medina, AM Davies, ST Buckley, Novel tools for investigations of cytoskeletal re-arrangement during alveolar epithelial-mesenchymal transition, FASEB J, Experimental Biology Meeting 2011, Washington, DC, 09-13/04/2011, 25, 2011, pp856.2Conference Paper, 2011
Medina C, Santos-Martinez MJ, Santana A, Paz-Cabrera MC, Johnston MJ, Mourelle M, Salas A, Guarner F., Transforming growth factor-beta type 1 receptor (ALK5) and Smad proteins mediate TIMP-1 and collagen synthesis in experimental intestinal fibrosis., The Journal of Pathology, 224, (4), 2011, p461 - 472Journal Article, 2011, DOI
C Ehrhardt, C Medina, AM Davies, ST Buckley, Using atomic force microscopy and high-content analysis for investigations into cytoskeletal re-arrangement during TGF-β1-induced alveolar epithelial-mesenchymal transition, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2011, Denver, CO, 13-18/05/2011, 183, 2011, ppA3501Conference Paper, 2011
C Ehrhardt, C Medina, AM Davies, ST Buckley, The receptor for advanced glycation end-products (RAGE) interacts with focal adhesion molecules in epithelial-mesenchymal transition (EMT) of alveolar epithelial cells, Am J Respir Crit Care Med , eeting of the American Thoracic Society 2011, Denver, CO, 13-18/05/2011, 183, 2011, ppA3502Conference Paper, 2011
J Wang, C Medina, MW Radomski, JF Gilmer, N-subsituted homopiperazine barbiturates as gelatinase inhibitors, Bioorganic & Medicinal Chemistry, 19, (16), 2011, p4985-4999Journal Article, 2011, DOI , URL , TARA - Full Text
ST Buckley, C Medina, AM Davies, C Ehrhardt, Cytoskeletal re-arrangement in TGF-beta1-induced alveolar epithelial-mesenchymal transition studied by atomic force microscopy and high-content analysis, Nanomed - Nanotechnol Biol Med, 8, (3), 2012, p355-364Journal Article, 2012, DOI , URL , TARA - Full Text
Corbalan, J.J., Medina, C., Jacoby, A., Malinski, T., Radomski, M.W. , Amorphous silica nanoparticles trigger nitric oxide/peroxynitrite imbalance in human endothelial cells - inflammatory and cytotoxicity effects. , International Journal of Nanomedicine, 6, 2011, p1 - 15Journal Article, 2011, DOI , URL , TARA - Full Text
Santos-Martinez, M.J., Prina-Mello, A., Medina, C., Radomski, M.W. , Analysis of platelet function: role of microfluidics and nanodevices, Analyst, 136, 2011, p5120 - 5126Review Article, 2011, DOI , TARA - Full Text
Harmon, S., Inkielewicz-Stepniak, I., Jones, M., Ledwidge, Santos-Martinez, M.J., Medina, C., Radomski, M.W., Gilmer, J.F, Mechanisms of aggregation inhibition by aspirin and nitrate-aspirin prodrugs in human platelets, Journal of Pharmacy and Pharmacology, 64, (1), 2012, p77 - 89Journal Article, 2012, DOI , URL , TARA - Full Text
Wang, J., O'Sullivan, S., Harmon, S., Keaveney, R., Radomski, M., Medina, C., Gilmer, J. , Design of barbiturate-nitrate hybrids that inhibit MMP-9 and secretion, Journal of Medicinal Chemistry, 55, 2012, p2154 - 2162Journal Article, 2012, DOI
Medina C, Harmon S, Inkielewicz I, Santos-Martinez MJ, Jones M, Cantwell P, Bazou D, Ledwidge M, Radomski MW, Gilmer JF., Differential Inhibition of Tumor Cell-Induced Platelet Aggregation by Nicotinate Aspirin Prodrug (ST0702) and Aspirin., British Journal of Pharmacology, 166, (3 ), 2012, p938 - 949Journal Article, 2012, DOI , TARA - Full Text
Umerska A, Paluch KJ, Inkielewicz-Stępniak I, Santos-Martinez MJ, Corrigan OI, Medina C, Tajber L., Exploring the assembly process and properties of novel crosslinker-free hyaluronate-based polyelectrolyte complex nanocarriers, International Journal of Pharmaceutics, 436, (1-2), 2012, p75 - 87Journal Article, 2012, DOI , URL , TARA - Full Text
Wang, J., Radomski, M.W., Medina, C., Gilmer, J.F, MMP inhibition by barbiturate homodimers, Bioorganic and Medicinal Chemistry Letters, 23, 2013, p444 - 447Journal Article, 2013, TARA - Full Text
I Inkielewicz-Stepniak, J Gilmer, M Radomski, W Czarnowski, C Medina, The effect of new aspirin prodrugs on blood platelet and tumor cells in an 'in vitro'study, Toxicology Letters, XII International Congress of Toxicology, Barcelona, 196, 2010, ppS258-S259Conference Paper, 2010
O'Sullivan, S., Medina, C., Ledwige, M., Radomski, M.W., Gilmer, J.F, Nitric oxide-matrix metaloproteinase-9 interactions: Biological and pharmacological significance: NO and MMP-9 interactions, Biochimica et biophysica acta, 1843, (3), 2014, p603-617Review Article, 2014, DOI , TARA - Full Text
Radziwon-Balicka A, Medina C, O'Driscoll L, Treumann A, Bazou D, Inkielewicz-Stepniak I, Radomski A, Jow H, Sawicki G, Radomski MW., Platelets increase survival of adenocarcinoma cells challenged with anticancer drugs: mechanisms and implications for chemoresistance. , Brit. J. Pharmacol., 167, (4), 2012, p787 - 804Journal Article, 2012, DOI , URL , TARA - Full Text
D Bazou, MJ Santos-Martinez, C Medina, MW Radomski, Elucidation of Flow Mediated TCIPA Using an Ultrasound Standing Wave Trap, British Journal of Pharmacology, 162, (7), 2011, p1577 - 1589Journal Article, 2011, TARA - Full Text
C Medina, MJ Santos-Martinez, A Santana, MC Paz-Cabrera, MJ Johnston, M Mourelle, A Salas, F Guarner, TGF-Beta Type 1 Receptor (ALK5) and SMAD Proteins Mediate TIMP-1 and Collagen Synthesis in Experimental Intestinal Fibrosis, Journal of Pathology, 224, 2011, p461 - 472Journal Article, 2011
S Harmon, I Inkielewicz, M Jones, M Ledwidge, C Medina, MW Radomski, JF Gilmer, In Vitro Pharmacology of Aspirin Prodrugs in Human Platelets , J Pharm Pharmacol , 64, 2012, p77 - 89Journal Article, 2012, TARA - Full Text
MJ Santos-Martinez, I Inkielewicz-Stepniaka, C Medina, K Rahme, DM D'Arcy, D Fox, JD Holmes, H Zhang, MW Radomski, The Use of Quartz Crystal Microbalance with Dissipation (QCM-D) for Studying Nanopaticle-Induced Platelet Aggregation., International Journal of Nanomedicine, 7, 2012, p243 - 255Journal Article, 2012, TARA - Full Text
JJ Corbalan, C Medina, A Jacoby, T Malinski, MW Radomski, Amorphus Silica Nanopartilces Aggregate Human Platelets: Potential Implications for Vascular Haemostasis., International Journal of Nanomedicine, 7, 2012, p631 - 639Journal Article, 2012, TARA - Full Text
J Wang, S O'Sullivan, S Harmon, R Keaveney, MW Radomski, C Medina, JF Gilmer, DESIGN OF BARBITURATE-NITRATE HYBRIDS THAT INHIBIT MMP-9 ACTIVITY AND SECRETION, Journal Medicinal Chemistry, 55, (5), 2012, p2154 - 2162Journal Article, 2012
Radziwon-Balicka A, Santos-Martinez MJ, Corbalan JJ, O'Sullivan S, Treumann A, Gilmer JF, Radomski MW, Medina C, Mechanisms of platelet-stimulated colon cancer invasion: role of clusterin and thrombospondin 1 in regulation of the P38MAPK-MMP-9 pathway., Carcinogenesis, 35, (2), 2014, p324 - 332Journal Article, 2014, TARA - Full Text
Santos-Martinez, M.J., Inkielewicz-Stepniak, I., Medina, C., Rahme, K., Arcy, D., Fox, D., Holmes, J.D., Zhang, H., Radomski, M.W., The use of quartz crystal microbalance with dissipation (QCM-D) for studying nanoparticle-induced platelet aggregation, International Journal of Nanomedicine, 7, 2012, p243-255Journal Article, 2012
Santos-Martinez, M.J., Rahme, K., Corbalan, J.J., Faulkner, C., Holmes, J., Tajber, L., Medina, C., Radomski, M.W. , Pegylation increases platelet biocompatibility of gold nanoparticles. , Journal of Biomedical Nanotechnology, 10, 2014, p1004 - 1015Journal Article, 2014, URL
Inkielewicz-Stepniak, I., Santos-Martinez, M.J., Medina, C., Radomski, M.W. , Pharmacological and toxicological effects of co-exposure of human gingival fibroblasts to silver nanoparticles and sodium fluoride, International Journal of Nanomedicine, 9, 2014, p1677 - 1678Journal Article, 2014, DOI , TARA - Full Text
O'Sullivan S, Gilmer JF, Medina C, Matrix metalloproteinases in inflammatory bowel disease: an update, Mediators of Inflammation, 2015, p964131-Review Article, 2015, DOI , TARA - Full Text
N Glezeva, M Santos-Martinez, C Watson, K Mcdonald, C Medina, J Gilmer, M Ledwidge, Inhibition of thromboxane pathways in monocytes impedes cell invasiveness, European Journal of Heart Failure, 16, 2014, pp208-209Conference Paper, 2014
Umerska A, Paluch KJ, Santos-Martinez MJ, Corrigan OI, Medina C, Tajber L, Self-assembled hyaluronate/protamine polyelectrolyte nanoplexes: synthesis, stability, biocompatibility and potential use as peptide carriers, Journal of Biomedical Nanotechnology, 10, (12), 2014, p3658 - 3673Journal Article, 2014, DOI , TARA - Full Text

Santos-Martinez, M.J., Medina, C., Radomska, A., Radomski, M.W., Clinician-scientist: a hobby for few, career prospects for some and training for all practicioners? , 2005, 17-19Report
Santos-Martinez, M.J., Medina, C., Booth, J., Radomski, M.W., A novel method for the measurement of platelet aggregation under flow conditions using nanobalance., All-Ireland Schools of Pharmacy Research Seminar 2007, Dublin, Ireland, 2-3 April 2007, 2007Oral Presentation
Hopkins, H., O'Brien, L., Radomska, A., Medina, C., Gilmer, J.F., Radomski, M.W., Inhibition of human platelet aggregation by a novel isosorbide-based aspirin analogue ISAS, All-Ireland Schools of Pharmacy Research Seminar 2007, Dublin, Ireland, 2-3 April 2007, 2007, pp23 - 23Oral Presentation
Radziwon A, O'Dwyer R, Medina C, Radomski MW., Inhibition of platelet-stimulated matrix metalloproteinase-9 generation in Caco-2 cells by selective MAP kinase inhibitors., Conference All-Ireland Schools of Pharmacy, 2008Meeting Abstract
Radziwon, A., Medina, C., O'Driscoll, L., Radomski, M.W., Platelets inhibit drug chemotherapy-induced cancer apoptosis, Joint Schools of Pharmacy Research Seminar, Trinity College Dublin, 26-27 March 2009, 2009Oral Presentation
Santos-Martinez, M.J., Medina, C., Prina-Mello, A., Conroy, J., Samuels, S.P., Volkov, Y., Radomski, M.W., Nanobalance: a novel method for the measurement of flow-induced platelet aggregation, Nanomedicine: Seminar and Workshop, Centre for Research on Nanostructures and Nanodevices Trinity College Dublin, 29 June 2009, 2009Poster
Corbalan, J.J., Medina, C., Radomski, M.W., Differential stimulation of inflammatory reactions by silica and poystyrene nanoparticles, Nanomedicine Seminar and Workshop, Centre for Research on Adaptive Nanostructures and Nanodevices Trinity College Dublin,, 29 June 2009, 2009Poster

Recognition

CRANN Innovation Award, TCD 2010
Fellowship of Secretaria de Estado de Educacion y Universidades, Ministry of Education (MECD/Fulbright), Spain (EX2004-0396) to gain experience overseas 2004-2006
SFI Stokes lectureship 2008-2013

Irish Platelet Working Group present
Spanish Gastroenterologist Association present
Irish Association of Pharmacologists present
Canary Gastroetnerologist Association present
Spanish Research Society in Ireland present

Member of the Canary Gastroenterologist Association. 2001
REFEREE FOR THE FOLLOWING JOURNALS: Nanomaterials, Int J Nanomedicine, The Journal of Pathology, Journal of Leukocyte Biology, BBA-Molecular Cell Research, Journal of Experimental Pharmacology and Therapeutics, British Journal of Pharmacology, Neurogastrointestinal Motility, European Journal of Gastroenterology and Hepatology, Thrombosis Research, The Journal of Obstetrics and Gynaecology Research, European Journal of Obstetrics & Gynecology and Reproductive Biology.
Member of the Irish Platelet Working Group 2011
REVIEWER FOR THE FOLLOWING FUNDING AGENCIES: Philip Morris External Research Program Award, USA; Inflammatory Bowel Disease Grants, The Broad Foundation, USA; ComGRAD grants, Canada.
Member of organizing committee of All Ireland Schools of Pharmacy meeting which is held annually throughout the country.
Member of the Irish Association of Pharmacologists 2017
Member of the Canary Gastroenterologist Association. 2001
REFEREE FOR THE FOLLOWING JOURNALS: Nanomaterials, Int J Nanomedicine, The Journal of Pathology, Journal of Leukocyte Biology, BBA-Molecular Cell Research, Journal of Experimental Pharmacology and Therapeutics, British Journal of Pharmacology, Neurogastrointestinal Motility, European Journal of Gastroenterology and Hepatology, Thrombosis Research, The Journal of Obstetrics and Gynaecology Research, European Journal of Obstetrics & Gynecology and Reproductive Biology.
Memner of the Spanish Gastroenterologist Association 2001
Member of Spanish Research Society in Ireland 2017
Member of organizing committee of All Ireland Schools of Pharmacy meeting which is held annually throughout the country.
Member of the Irish Association of Pharmacologists 2017
Member of the Irish Platelet Working Group 2011
REVIEWER FOR THE FOLLOWING FUNDING AGENCIES: Philip Morris External Research Program Award, USA; Inflammatory Bowel Disease Grants, The Broad Foundation, USA; ComGRAD grants, Canada.
Memner of the Spanish Gastroenterologist Association 2001
Member of Spanish Research Society in Ireland 2017