Dr. Carsten Ehrhardt

• Amaro MI, Tewes F, Gobbo O, Tajber L, Corrigan OI, Ehrhardt C, Healy AM, Formulation, stability and pharmacokinetics of sugar-based salmon calcitonin-loaded nanoporous/nanoparticulate microparticles (NPMPs) for inhalation, International Journal of Pharmaceutics, 483, (1-2), 2015, p6-18Journal Article, 2015, DOI , TARA - Full Text
• JJ Salomon, Y Hagos, S Petzke, A Kühne, JC Gausterer, KI Hosoya, C Ehrhardt, Beta-2 adrenergic-agonists are substrates and inhibitors of human organic cation transporter 1, Mol Pharm, 12, (8), 2015, p2633-2641Journal Article, 2015, DOI
• M Takano, N Sugimoto, C Ehrhardt, R Yumoto, Functional expression of PEPT2 in the human distal lung epithelial cell line NCl-H441, Pharm Res, 32, (12), 2015, p3916-3926Journal Article, 2015, DOI
• JJ Salomon, JC Gausterer, T Yahara, KI Hosoya H Huwer, M Hittinger, N Daum-Schneider, CM Lehr, C Ehrhardt, Organic cation transporter function in different in vitro models of human lung epithelium, Eur J Pharm Sci, 80, 2015, p82-88Journal Article, 2015, DOI
• Y Tega, C Yuzurihara, Y Kubo, SI Akanuma, C Ehrhardt, KI Hosoya, Functional expression of nicotine influx transporter in A549 human alveolar epithelial cells, Drug Metab Pharmacokinet, 31, (1), 2016, p99-101Journal Article, 2016, DOI
• S Nickel, CG Clerkin, MA Selo, C Ehrhardt, Transport mechanisms at the pulmonary mucosa: implications for drug delivery, Expert Opin Drug Deliv, 13, (5), 2016, p667-690Review Article, 2016, DOI
• Tewes, F, Gobbo, OL, Ehrhardt, C, Healy, AM, Amorphous calcium carbonate based-microparticles for peptide pulmonary delivery, ACS Applied materials and interfaces, 8, (2), 2016, p1164-1175Journal Article, 2016, DOI , TARA - Full Text
• Zelikin AN, Ehrhardt C, Healy AM, Materials and methods for delivery of biological drugs, Nature Chemistry, 8, (11), 2016, p997-1007Review Article, 2016, DOI
• X Hu, FF Yang, CY Liu, C Ehrhardt, YH Liao, In vitro uptake and transport studies of PEG-PLGA polymeric micelles in respiratory epithelial cells, Eur J Pharm Biopharm, 114, 2017, p29-37Journal Article, 2017, DOI
• American Journal of Physiology - Lung Cellular and Molecular Physiology , Bethesda, MD, American Physiological Society, 2015Editorial Board, 2015
• Drug Delivery Letters, Saif Zone, Sharjah, U.A.E., Bentham Science Publishers, 2010Editorial Board, 2010
• European Journal of Pharmaceutics and Biopharmaceutics, Amsterdam, The Netherlands, Elsevier Science, [eds.], 2017Editorial Board, 2017
• Journal of Aerosol Medicine and Pulmonary Drug Delivery, Rochelle, NY, Mary Ann Liebert, Inc., 2015Editorial Board, 2015
• Journal of Pharmaceutical Sciences, New York, NY, Elsevier Science, [Member of the Scientific Advisory Board], 2014Editorial Board, 2014
• C Ehrhardt, P Bäckman, W Couet, C Edwards, B Forbes, M Fridén, M Gumbleton, KI Hosoya, Y Kato, T Nakanishi, M Takano, T Terasaki, R Yumoto(ed.), Current progress toward a better understanding of drug disposition within the lungs: summary proceedings of the 1st Workshop on Drug Transporters in the Lungs, J Pharm Sci, Dublin, Ireland, 106, (9), 22-23/09/2016, 2017, 2234 - 2244 pProceedings of a Conference, 2017, DOI
• S Nickel, MA Selo, J Fallack, H Huwer, N Schneider-Daum, CM Lehr, C Ehrhardt, Expression and activity of breast cancer resistance protein (BCRP) in human distal lung epithelial cells in vitro, Pharm Res, 34, (12), 2017, p2477-2487Journal Article, 2017, DOI
• HJ Gukasyan, T Uchiyama, KJ Kim, C Ehrhardt, SK Wu, Z Borok, VHL Lee, ED Crandall, Oligopeptide transport in rat lung alveolar epithelial cells is mediated by Pept2, Pharm Res, 34, (12), 2017, p2488-2497Journal Article, 2017, DOI
• W de Kruif, C Ehrhardt, Inhalation delivery of complex drugs - the next steps, Curr Opin Pharmacol, 36, 2017, p52-57Review Article, 2017
• Journal of Pharmaceutical Sciences, New York, Elsevier on behalf of the American Pharmacists Association (United States), [eds.], 2018-2018Editorial Board, 2018
• C Ehrhardt, Inhalation Biopharmaceutics: Progress Towards Comprehending the Fate of Inhaled Medicines, Pharm Res, 34, (12), 2017, p2451-2453Journal Article, 2017, DOI
• Pharm Res, Inhalation Biopharmaceutics, 34, 12, (2017), 2451-2613p, C Ehrhardt, [Theme Editor]Journal, 2017, URL
• A Al-Hayali, MA Selo, C Ehrhardt, S Velaga, Investigation of supersaturation and in vitro permeation of the poorly water-soluble drug ezetimibe, Eur J Pharm Sci, 117, 2018, p147-153Journal Article, 2018
• European Journal of Pharmaceutical Sciences, Elsevier, [Section Editor], 2018Editorial Board, 2018
• Lung transporters & absorption mechanisms in the lungs in, editor(s)HM Mansour, AJ Hickey , Inhalation Aerosols, Physical and Biological Basis for Therapy, London, Informa HealthCare, 2019, pp57 - 70, [MA Selo, HHA Al-Alak, C Ehrhardt]Book Chapter, 2019
• Pharmaceutics, Basel, Switzerland, MDPI, [eds.], 2019Editorial Board, 2019
• L Duse, MR Agel, SR Pinnapireddy, J Schäfer, MA Selo, C Ehrhardt, U Bakowsky, Photodynamic therapy of ovarian carcinoma cells with curcumin-loaded biodegradable polymeric nanoparticles, Pharmaceutics, 11, (6), 2019, p282-Journal Article, 2019
• JJ Salomon, JC Gausterer, MA Selo, KI Hosoya, H Huwer, N Schneider-Daum, CM Lehr, C Ehrhardt, OCTN2-mediated acetyl-L-carnitine transport in human pulmonary epithelial cells in vitro, Pharmaceutics, 11, (8), 2019, p396-Journal Article, 2019
• C Ehrhardt, C Kneuer, J Fiegel, J Hanes, UF Schaefer, KJ Kim, CM Lehr, Influence of apical fluid volume on the development of functional intercellular junctions in the human epithelial cell line 16HBE14o-: implications for the use of this cell line as an in vitro model for bronchial drug absorption studies, Cell Tissue Res, 308, (3), 2002, p391 - 400Journal Article, 2002, DOI
• C Ehrhardt, C Kneuer, M Laue, UF Schaefer, KJ Kim, CM Lehr, 16HBE14o- human bronchial epithelial cell layers express P-glycoprotein, lung resistance-related protein and caveolin-1, Pharm Res, 20, (4), 2003, p545 - 551Journal Article, 2003, DOI
• J Fiegel, C Ehrhardt, UF Schaefer, CM Lehr, J Hanes, Large porous particle impingement on lung epithelial cell monolayers - Toward improved particle characterization in the lung, Pharm Res, 20, (5), 2003, p788 - 796Journal Article, 2003, DOI
• G Abraham, C Kneuer, C Ehrhardt, W Honscha, FR Ungemach, Expression of functional β2-adreneric receptors in lung epithelial cell lines 16HBE14o - Calu-3 and A549, Biochim Biophys Acta, 1691, (2-3), 2004, p169 - 179Journal Article, 2004, DOI
• KJ Kim, Z Borok, C Ehrhardt, BC Willis, CM Lehr, ED Crandall, Estimation of paracellular conductance of primary rat alveolar epithelial cell monolayers, J Appl Physiol, 98, (1), 2005, p138 - 143Journal Article, 2005, DOI
• C Ehrhardt, C Kneuer, C Bies, CM Lehr, KJ Kim, U Bakowsky, Salbutamol is actively absorbed across human respiratory epithelial cell layers, Pulm Pharmacol Ther, 18, (3), 2005, p165 - 170Journal Article, 2005, DOI
• S Anabousi, M Laue, CM Lehr, U Bakowsky, C Ehrhardt, Assessing transferrin modification of liposomes by atomic force microscopy and transmission electron microscopy, Eur J Pharm Biopharm, 60, (2), 2005, p295 - 303Journal Article, 2005, DOI
• U Becker, C Ehrhardt, UF Schaefer, HJ Gukasyan, KJ Kim, VHL Lee, CM Lehr, Tissue distribution of moxaverine-hydrochloride in the rabbit eye and plasma, J Ocul Pharmcol Ther, 21, (3), 2005, p210 - 216Journal Article, 2005, DOI
• Arzneistoffabsorption durch die Lungenschleimhaut - Zellkulturmodelle und partikuläre Arzneistoffträger in, editor(s)G Scheuch , Aerosole in der Inhalationstherapie VI, München, dustriTBmed, 2002, pp23 - 38, [C Ehrhardt, S Fuchs, R Abu-Dahab, UF Schaefer, CM Lehr]Book Chapter, 2002
• Bronchial epithelial cell cultures in, editor(s)CM Lehr , Cell culture models of biological barriers, London, Taylor & Francis, 2002, pp211 - 227, [C Meaney, BI Florea, C Ehrhardt, UF Schaefer, CM Lehr, HE Junginger, G Borchard]Book Chapter, 2002
• C Ehrhardt, J Fiegel, S Fuchs, R Abu-Dahab, UF Schaefer, J Hanes, CM Lehr, Drug absorption by the respiratory mucosa - cell culture models and particulate drug carriers, J Aerosol Med, 15, (2), 2002, p131-139Review, 2002, DOI
• C Ehrhardt, C Kneuer, U Bakowsky, Selectins - an emerging target for drug delivery, Adv Drug Deliv Rev, 56, (4), 2004, p527-549Review, 2004, DOI
• Toward improved particle characterization in the lung: impingement of large porous particles on lung epithelial cell monolayers in, editor(s)G Scheuch , Aerosole in der Inhalationstherapie VIII, München, dustriTBmed, 2004, pp87 - 93, [C Ehrhardt, J Fiegel, U Bakowsky, UF Schaefer, J Hanes, CM Lehr]Book Chapter, 2004
• C Ehrhardt, KJ Kim, CM Lehr, Isolation and culture of human alveolar epithelial cells, Methods Mol Med, 107, 2005, p207-216Review, 2005, DOI
• B Forbes, C Ehrhardt, Human respiratory epithelial cell culture for drug delivery application, Eur J Pharm Biopharm, 60, (2), 2005, p193-205Review, 2005, DOI
• CM Lehr, S Fuchs, K Roemer, M Laue, UF Schaefer, C Ehrhardt, Cell culture models of alveolar and airway mucosa, Proc VIIth Conference on Nasal and Pulm Drug Del, Conference VII on Nasal and Pulmonary Drug Delivery, Barcelona, Spain, 15.-17.09.2003, 2003, pp24 - 26Conference Paper, 2003
• Pharmaceutical Research, Springer, [eds.], 2020Editorial Board, 2020
• S Mairinger, JA Sake, I Hernández Lozano, T Filip, M Sauberer, J Stanek, T Wanek, C Ehrhardt*, O Langer*, Assessing the Activity of Multidrug Resistance-Associated Protein 1 at the Lung Epithelial Barrier, J Nucl Med , 61, (11), 2020, p1650 - 1657Journal Article, 2020, DOI
• MA Selo*, AS Delmas, L Springer, V Zoufal, JA Sake, CG Clerkin, H Huwer, N Schneider-Daum, CM Lehr, S Nickel, O Langer, C Ehrhardt*, Tobacco smoke and inhaled drugs alter expression and activity of multidrug resistance-associated protein-1 (MRP1) in human distal lung epithelial cells in vitro, Front Bioeng Biotechnol, 8, 2020, p1030-Journal Article, 2020, DOI
• MA Selo*, JA Sake, C Ehrhardt, JJ Salomon*, Organic cation transporters in the lung - current and emerging (patho)physiological and pharmacological concepts, Int J Mol Sci, 21, (23), 2020, p9168-Journal Article, 2020, DOI
• H Saeed*, H Osama, YM Madney, HS Harb, MA Abdelrahman, C Ehrhardt, MEA Abdelrahim, COVID-19; current situation and recommended interventions, Int J Clin Pract, 75, (5), 2021, pe13886-Review Article, 2021, DOI
• A Yıldız-Peköz, C Ehrhardt*, Advances in Pulmonary Drug Delivery, Pharmaceutics, 12, (10), 2020, p911-Journal Article, 2020, DOI
• P Li, C Ehrhardt, C Loehbach, CM Lehr, U Bakowsky, Tissue engineering, surface coating and pharmaceutical nanotechnology, Proceedings of the International School on Advanced Material Science and Technology, Smart materials and Nanotechnologies V, Jesi, Italy, 26.-29.08.2003, edited by A Lodini, F Rustichelli , 5, 2004, pp26 - 41Conference Paper, 2004
• C Ehrhardt, The lung in a box - can pulmonary PK really be predicted from cell culture models?, Eur J Pharm Sci, EUFEPS 2004, Bruxelles, Belgium, 17.-20.10.2004, 23, (S1), 2004, ppS26 - S27Conference Paper, 2004
• MA Selo, JA Sake, KJ Kim, C Ehrhardt, In vitro and ex vivo models n inhalation biopharmaceutical research - advances, challenges and future perspectives, Adv Drug Deliv Rev, 177, 2021, p113862-Review Article, 2021, URL
• JC Coco, JA Ataide, JA Sake, EB Tambourgi, C Ehrhardt, PG Mazzola, In vitro antioxidant and wound healing properties of baru nut extract (Dipteryx alata Vog.) in pulmonary epithelial cells for therapeutic application in chronic pulmonary obstructive disease (COPD), Nat Prod Res, 2021Journal Article, 2021
• JE Hastedt, P Bäckman, A Cabal, A Clark, C Ehrhardt, B Forbes, AJ Hickey, G Hochhaus, W Jiang, S Kassinos, P Kuehl, D Prime, YJ Son, S Teague, U Tehler, J Wylie, The iBCS: 1. Principles and Framework of an Inhalation-based BCS, Mol Pharm, 19, (7), 2022, p2032 - 2039Journal Article, 2022
• P Bäckman, A Cabal, A Clark, C Ehrhardt, B Forbes, JE Hastedt, AJ Hickey, G Hochhaus, W Jiang, S Kassinos, P Kuehl, D Prime, YJ Son, S Teague, U Tehler, J Wylie, The iBCS: 2. Mechanistic Modelling of Pulmonary Availability of Inhaled Medicines versus Critical Product Attributes, Mol Pharm, 19, (7), 2022, p2040 - 2047Journal Article, 2022
• I Hernández-Lozano, S Mairinger, T Filip, M Sauberer, T Wanek, J Stanek, JA Sake, T Pekar, C Ehrhardt, O Langer, PET imaging to assess the impact of P-glycoprotein on pulmonary drug delivery in rats, J Control Release, 342, 2022, p44 - 52Journal Article, 2022
• Menzel V, Ziegler M, Hante N, Sake JA, Santos-Martinez MJ, Ehrhardt C, Kasper M, Barth K., Fyn-kinase and caveolin-1 in the alveolar epithelial junctional adherence complex contribute to the early stages of pulmonary fibrosis, Eur J Pharm Sci, 175, 2022, p106236-Journal Article, 2022
• S Mairinger, I Hernández-Lozano, T Filip, M Sauberer, M Löbsch, J Stanek, T Wanek, JA Sake, T Pekar, C Ehrhardt, O Langer, Impact of P-gp and BCRP on pulmonary drug disposition assessed by PET imaging in rats, J Control Release, 349, 2022, p109 - 117Journal Article, 2022
• S Mairinger, I Hernández-Lozano, C Ehrhardt, O Langer, Nuclear imaging methods as novel tools in the assessment of pulmonary drug disposition, Expert Opin Drug Deliv, 2022Journal Article, 2022
• Sake JA, Selo MA, Burtnyak L, Dähnhardt HE, Helbet C, Mairinger S, Langer O, Kelly VP, Ehrhardt C., Knockout of ABCC1 in NCI-H441 cells reveals CF to be a suboptimal substrate to study MRP1 activity in organotypic in vitro models., European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 181, 2023, p106364Journal Article, 2023, DOI
• S Mairinger, I Hernández-Lozano, T Filip, M Löbsch, J Stanek, M Zeitlinger, M Hacker, N Tournier, T Wanek, C Ehrhardt, O Langer, Influence of P-glycoprotein on pulmonary disposition of the model substrate [11C]metoclopramide assessed by PET imaging in rats, Eur J Pharm Sci , 183, 2023, p106404-Journal Article, 2023
• LL Tundisi, JA Ataide*, JSR Costa, DF Coêlho, RB Liszbinski; AM Lopes, L Oliveira-Nascimento, MB de Jesus, AF Jozala, C Ehrhardt, PG Mazzola, Nanotechnology as a tool to overcome macromolecules delivery issues. , Colloids Surf B , 222, 2023, p113043-Journal Article, 2023
• S Mairinger, I Hernández-Lozano, L Zachhuber, T Filip, M Löbsch, M Zeitlinger, M Hacker, C Ehrhardt, O Langer, Effect of budesonide on pulmonary activity of multidrug resistance-associated protein 1 assessed with PET imaging in rats. , Eur J Pharm Sci, 184, 2023, p106414-Journal Article, 2023
• Adhesion molecule-modified cardiovascular prostheses: characterization of cellular adhesion in a cell culture model and by cellular force spectroscopy in, editor(s)W Possart , Adhesion: current research and applications, Weinheim,Germany, Wiley-VCH, 2005, pp159 - 174, [U Bakowsky, C Ehrhardt, C Loehbach, P Li, C Kneuer, D Jahn, D Hoekstra, CM Lehr]Book Chapter, 2005
• MJ Lyons, C Ehrhardt, JJ Walsh, Orellanine: From fungal origins to a future cancer treatment, J Nat Prod, 86, (6), 2023, p620-1631Review Article, 2023, URL
• B Falade, C Ehrhardt, In vitro dissolution testing methods for inhaled drugs, Istanbul J Pharm, 53, (2), 2023, p239-250Review Article, 2023, URL
• JE Hastedt, P Bäckman, A Cabal, A Clark, C Ehrhardt, B Forbes, AJ Hickey, G Hochhaus, W Jiang, S Kassinos, P Kuehl, D Prime, YJ Son, S Teague, U Tehler, J Wylie, iBCS: 3. A Biopharmaceutics Classification System for Inhaled Drug Delivery, Mol Pharm, 21, (1), 2024, p164-172Journal Article, 2024, URL
• C Ehrhardt, EM Collnot, C Baldes, M Laue, KJ Kim, CM Lehr, Towards an in vitro model of cystic fibrosis small airway epithelium: Characterisation of the human bronchial epithelial cell line CFBE41o - Cell Tissue Res, 323, (3), 2006, p405 - 415Journal Article, 2006, DOI
• N Demling, C Ehrhardt, M Kasper, M Laue, L Knels, EP Rieber, Promotion of cell adherence and spreading: a novel function of RAGE, the highly selective differentiation marker of alveolar epithelial type I cells, Cell Tissue Res, 323, (3), 2006, p475 - 488Journal Article, 2006, DOI
• C Kneuer, C Ehrhardt, H Bakowsky, MNV Ravi Kumar, V Oberle, CM Lehr, D Hoekstra, U Bakowsky, The influence of physicochemical parameters on the efficacy of non-viral DNA transfection complexes: A comparative study, J Nanosci Nanotechnol, 6, (9-10), 2006, p2776-2782Journal Article, 2006, DOI
• M Bur, H Huwer, CM Lehr, N Hagen, M Guldbrandt, KJ Kim, C Ehrhardt, Assessment of protein transport rates across primary human alveolar epithelial cell monolayers, Eur J Pharm Sci, 28, (3), 2006, p196-203Journal Article, 2006, DOI
• S Anabousi, E Kleemann, U Bakowsky, T Kissel, T Schmehl, T Gessler, W Seeger, CM Lehr, C Ehrhardt, Effect of PEGylation on the stability of liposomes during nebulisation and in lung surfactant, J Nanosci Nanotechnol, 6, (9-10), 2006, p3010-3016Journal Article, 2006, DOI
• G Sharma, S Anabousi, C Ehrhardt, MNV Ravi Kumar, Liposomes as targeted drug delivery systems in the treatment of breast cancer, J Drug Target, 14, (5), 2006, p301-310Review, 2006, DOI
• S Anabousi, U Bakowsky, M Schneider, H Huwer, CM Lehr, C Ehrhardt, In vitro assessment of transferrin-conjugated liposomes as drug delivery systems for the inhalation therapy of lung cancer, Eur J Pharm Sci, 29, (5), 2006, p367 - 374Journal Article, 2006, DOI
• S Endter, U Becker, N Daum, H Huwer, CM Lehr, M Gumbleton, C Ehrhardt, P-glycoprotein (MDR1) functional activity in human alveolar epithelial cell monolayers, Cell Tissue Res, 328, (1), 2007, p77-84Journal Article, 2007, DOI
• A Steimer, H Franke, Eleonore Haltner-Ukomado, M Laue, C Ehrhardt, CM Lehr, Monolayers of porcine alveolar epithelial cells in primary culture as an in vitro model for drug absorption studies, Eur J Pharm Biopharm, 66, (3), 2007, p372-382Journal Article, 2007, DOI
• U Becker, C Ehrhardt, N Daum, C Baldes, UF Schaefer, K Rupprecht, KJ Kim, CM Lehr, Expression of ABC-transporters in human corneal tissue and the transformed cell line, HCE-T, J Ocul Pharmacol Ther, 23, (2), 2007, p172-181Journal Article, 2007, DOI
• S Anabousi, U Bakowsky, C Ehrhardt, In vitro studies on liposomal systems for the inhalation treatment of lung cancer, J Aerosol Med , 16th Congress of the International Society for Aerosols in Medicine, Tours, France, 16.-20.06.2007, 20, (2), 2007, pp175-176Conference Paper, 2007
• H Bakowsky, T Richter, C Kneuer, D Hoekstra, U Rothe, C Ehrhardt, U Bakowsky, Adhesion characteristics and stability assessment of lectin-modified liposomes for site-specific drug delivery, Biochim Biophys Acta - Biomembranes, 1778, (1), 2008, p242-249Journal Article, 2008, DOI , TARA - Full Text
• U Becker, C Ehrhardt, M Schneider, Leon Muys, Dorothea Groß, Klaus Eschmann, UF Schaefer, CM Lehr, Comparative evaluation of corneal epithelial cell cultures for assessing ocular permeability, Altern Lab Anim, 36, (1), 2008, p33-44Journal Article, 2008
• H Sheridan, I Hook, J Coppins, C Nestor, C Ehrhardt, N Frankish, Inhibition of LFA-1 mediated T-cell motility by naphthoquinones, Planta Med, 74, (11), 2008, p1383-1387Journal Article, 2008, DOI
• In vitro models of the alveolar epithelial barrier in, editor(s)C Ehrhardt, KJ Kim , Drug Absorption Studies - In Situ, In Vitro and In Silico Models, New York, Springer, 2008, pp235 - 257, [C Ehrhardt, M Laue, KJ Kim]Book Chapter, 2008
• In vitro models of the bronchial epithelium in, editor(s)C Ehrhardt, KJ Kim , Drug Absorption Studies - In Situ, In Vitro and In Silico Models, New York, Springer, 2008, pp258 - 282, [C Ehrhardt, B Forbes, KJ Kim]Book Chapter, 2008
• C Ehrhardt, KJ Kim , Drug Absorption Studies - In Situ, In Vitro and In Silico Models, 1, New York, Springer, 2008, 1 - 698ppBook, 2008
• JL Sporty, L Horálková, C Ehrhardt, In vitro cell culture models for the assessment of pulmonary drug disposition, Expert Opin Drug Metab Toxicol. Expert Opin Drug Metab Toxicol, 4, (4), 2008, p333-345Review, 2008, DOI
• S Endter, C Ehrhardt, Drug disposition in the lung - recent advantages in understanding the role of drug transporters, Respiratory Drug Delivery, Respiratory Drug Delivery 2008, Scottsdale, AZ, 11-15/05/2008, 11, (1), 2008, pp65-72Conference Paper, 2008
• J Schäfer, J Sitterberg, C Ehrhardt, MNV Ravi Kumar, U Bakowsky, A new drug vehicle - lipid coated biodegradable nanoparticles, Adv Sci Technol, 57, 2008, p148-153Journal Article, 2008
• M Gaspar, U Bakowsky, C Ehrhardt, Inhaled liposomes - current strategies and future challenges, J Biomed Nanotechnol, 4, (3), 2008, p245-257Review, 2008, DOI
• Kneuer, C., Ehrhardt, C., Radomski, M.W., Bakowsky, U. , Selectins - potential pharmacological targets? , Drug Discovery Today, 11, (21-22), 2006, p1034-1040Review, 2006, DOI , URL
• L Horálková, A Radziwon, S Endter, R Andersen, R Koslowski, MW Radomski, P Dole al, C Ehrhardt., Characterisation of the R3/1 cell line as an alveolar epithelial cell model for drug disposition studies., Eur J Pharm Sci, 36, (4-5), 2009, p444-450Journal Article, 2009, DOI
• S Endter, D Francombe, C Ehrhardt, M Gumbleton, RT-PCR analysis of ABC - SLC- and SLCO-drug transporters in human lung epithelial cell models, J Pharm Pharmacol, 61, 2009, p583-591Journal Article, 2009, DOI
• E Passante, C Ehrhardt, H Sheridan, N Frankish, RBL-2H3 cells are an imprecise model for mast cell mediator release, Inflamm Res, 58, (9), 2009, p611-618Journal Article, 2009, DOI
• ST Buckley, C Medina, C Ehrhardt, Effect of TGF-β1 and inflammatory cytokines on EMT and cell migration in alveolar epithelial cells, Acta Physiol , 88th Annual Meeting of the German Physiological Society, Giessen, Germany, 22-25/03/2009, 195, (S669), 2009, pp14Conference Paper, 2009
• ST Buckley, C Medina, C Ehrhardt, Characterisation of the role of inflammatory cytokines in EMT and cell migration in alveolar epithelial cells, FASEB J, Experimental Biology Meeting 2009, New Orleans, LA, 18-22/04/2009, 23, 2009, pp997.2Conference Paper, 2009
• P Stasiak, C Ehrhardt, M Juzwa, M Sznitowska, Characterisation of a novel conjugate of ibuprofen with 3-hydroxybutyric acid oligomers, J Pharm Pharmacol, 61, 2009, p1119-1124Journal Article, 2009, DOI
• ST Buckley, C Medina, C Ehrhardt, Characterisation of the role of inflammatory cytokines in EMT and cell migration in alveolar epithelial cells, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2009, San Diego, CA, 15-20/05/2009, 179, (1), 2009, ppA5298Conference Paper, 2009
• MM Gaspar, O Gobbo, C Ehrhardt, Generation of liposome aerosols with the Aeroneb Pro and the AeroProbe nebulisers, J Liposome Res, 20, (1), 2010, p55-61Journal Article, 2010, DOI
• P Doolan, M Clynes, S Kennedy, JP Mehta, S Germano, C Ehrhardt, J Crown, L O'Driscoll, TMEM25, REPS2 and Meis 1: Favourable prognostic and predictive biomarkers for breast cancer, Tumor Biol, 30, (4), 2009, p200-209Journal Article, 2009, DOI , URL
• ST Buckley, C Medina, C Ehrhardt, Assessment of the role of inflammatory cytokines in EMT and cell migration in alveolar epithelial cells, Eur Respir J, European Respiratory Society Annual Congress 2009, Wien, Austria, 12-16/09/2009, 22, (S53), 2009, pp582Conference Paper, 2009
• J Sitterberg, A Özcetin, C Ehrhardt, U Bakowsky, Utilising atomic force microscopy for the characterisation of nanoscale drug delivery systems, Eur J Pharm Biopharm, 74, (1), 2010, p2-13Review, 2010, DOI , TARA - Full Text
• ST Buckley, C Medina, C Ehrhardt, The role of the receptor for advanced glycation end products (RAGE) in epithelial-mesenchymal transition in the lung: a potential therapeutic target, AAPS J, 23rd Annual Meeting of the AAPS, Los Angeles, CA, 08-12/11/2009, 11, (S2), 2009, ppW5006Conference Paper, 2009
• M Gaspar, F de Sousa Menezes, MW Radomski, C Ehrhardt, Effect of liposomal systems on human platelet aggregation, AAPS J, 22nd Annual Meeting of the AAPS, Atlanta, GA, 16-20/11/2008, 10, (S2), 2008, ppT2107Meeting Abstract, 2008
• J Sitterberg, MM Gaspar, C Ehrhardt, U Bakowsky, Atomic force microscopy for the characterization of proteoliposomes, Methods Mol Biol , 606, 2010, p351-361Review, 2010, DOI
• ST Buckley, C Medina, C Ehrhardt, Investigations into the role of RAGE and ERM proteins in EMT of human alveolar epithelial cells, Acta Physiologica, Joint Meeting of the Scandinavian and German Physiological Societies, København, Denmark, 27-30/3/2010, 198, (S677), 2010, pp146 - 147Conference Paper, 2010
• ST Buckley, C Medina, C Ehrhardt, RAGE and ERM proteins in EMT of human alveolar epithelial cells, FASEB J, Experimental Biology Meeting 2010, Anaheim, CA, 24-28/04/2010, 24, 2010, pp612.21Conference Paper, 2010
• ST Buckley, C Medina, C Ehrhardt, A role for RAGE and ERM proteins in EMT of human alveolar epithelial cells, Am J Respir Crit Care Med , Annual Meeting of the American Thoracic Society 2010, New Orleans, LA, 14-19/05/2010, 181, (1), 2010, ppA1234Conference Paper, 2010
• JS Patton, JD Brain, LA Davies, J Fiegel, M Gumbleton, KJ Kim, M Sakagami, R Vanbever, C Ehrhardt, The particle has landed - characterizing the fate of inhaled pharmaceuticals, J Aerosol Med Pulm Drug Deliv, 23, (S2), 2010, pS71-S87Review Article, 2010, DOI , URL , TARA - Full Text
• ST Buckley, C Ehrhardt, The receptor for advanced glycation end-products (RAGE) and the lung, J Biomed Biotechnol, 2010, 2010, p917108Review Article, 2010, DOI , URL , TARA - Full Text
• Tewes F, Tajber L, Corrigan OI, Ehrhardt C, Healy AM, Development and characterisation of soluble polymeric particles for pulmonary peptide delivery, European Journal of Pharmaceutical Sciences, 41, (2), 2010, p337 - 352Journal Article, 2010, DOI , URL , TARA - Full Text
• ST Buckley, C Medina, C Ehrhardt, Differential susceptibility to epithelial-mesenchymal transition (EMT) of alveolar, bronchial and intestinal epithelial cells in vitro and the effect of angiotensin II receptor inhibition, Cell Tissue Res, 342, (1), 2010, p39-51Journal Article, 2010, DOI
• L Baginski, G Tachon, F Falson, JS Patton, U Bakowsky, C Ehrhardt, RT-PCR analysis of proteolytic enzymes in cultures of human respiratory epithelial cells, J Aerosol Med Pulm Drug Deliv, 24, (2), 2011, p89-101Journal Article, 2011, DOI
• P Stasiak, M Sznitowska, C Ehrhardt, M Juzwa, A Kowalczyk, P Grieb, In vivo assessment of parenteral formulations of oligo(3-hydroxybutyric acid) conjugates with the model compound ibuprofen, AAPS PharmSciTech, 11, (4), 2010, p1636-1641Journal Article, 2010, DOI , URL , TARA - Full Text
• JJ Salomon, C Ehrhardt, Nanoparticles attenuate P-glycoprotein/MDR1 function in A549 human alveolar epithelial cells, Eur J Pharm Biopharm, 77, (3), 2011, p392-397Journal Article, 2011, DOI , URL , TARA - Full Text
• ST Buckley, C Medina, M Kasper, C Ehrhardt, Interplay between the receptor for advanced glycation end-products (RAGE), CD44 and focal adhesion molecules in epithelial-mesenchymal transition of alveolar epithelial cells, Am J Physiol Lung Cell Mol Physiol, 300, (4), 2011, pL548-L559Journal Article, 2011, DOI , TARA - Full Text
• In vitro cell culture models for evaluating controlled release pulmonary drug delivery in, editor(s)HDC Smyth, AJ Hickey , Controlled Pulmonary Drug Delivery, New York, Springer, 2011, pp417-442 , [ST Buckley, KJ Kim, C Ehrhardt]Book Chapter, 2011
• Liposomes for pulmonary drug delivery in, editor(s)HDC Smyth, AJ Hickey , Controlled Pulmonary Drug Delivery, New York, Springer, 2011, pp313-334 , [J Swaminathan, C Ehrhardt]Book Chapter, 2011
• E Paszko, C Ehrhardt, MO Senge, DP Kelleher, JV Reynolds, Nanodrug applications in photodynamic therapy, Photodiagnosis Photodyn Ther , 8, 2011, p14-29Review Article, 2011, DOI
• C Ehrhardt, C Medina, ST Buckley, Interaction of RAGE with focal adhesion molecules during alveolar epithelial-mesenchymal transition, FASEB J, Experimental Biology Meeting 2011, Washington, DC, 09-13/04/2011, 25, 2011, pp865.1Conference Paper, 2011
• C Ehrhardt, C Medina, AM Davies, ST Buckley, Novel tools for investigations of cytoskeletal re-arrangement during alveolar epithelial-mesenchymal transition, FASEB J, Experimental Biology Meeting 2011, Washington, DC, 09-13/04/2011, 25, 2011, pp856.2Conference Paper, 2011
• C Ehrhardt, C Medina, AM Davies, ST Buckley, Using atomic force microscopy and high-content analysis for investigations into cytoskeletal re-arrangement during TGF-β1-induced alveolar epithelial-mesenchymal transition, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2011, Denver, CO, 13-18/05/2011, 183, 2011, ppA3501Conference Paper, 2011
• C Ehrhardt, C Medina, AM Davies, ST Buckley, The receptor for advanced glycation end-products (RAGE) interacts with focal adhesion molecules in epithelial-mesenchymal transition (EMT) of alveolar epithelial cells, Am J Respir Crit Care Med , eeting of the American Thoracic Society 2011, Denver, CO, 13-18/05/2011, 183, 2011, ppA3502Conference Paper, 2011
• G Jenkins, A Blanchard, Z Borok, P Bradding, C Ehrhardt, A Fisher, N Hirani, S Johnson, M Königshoff, TM Maher, A Millar, H Parfrey, C Scotton, T Tetley, D Thickett, P Wolters, In search of the fibrotic epithelial cell: opportunities for a collaborative network, Throrax, 67, (2), 2012, p179-182Review, 2012, DOI
• ST Buckley, C Medina, AM Davies, C Ehrhardt, Cytoskeletal re-arrangement in TGF-beta1-induced alveolar epithelial-mesenchymal transition studied by atomic force microscopy and high-content analysis, Nanomed - Nanotechnol Biol Med, 8, (3), 2012, p355-364Journal Article, 2012, DOI , URL , TARA - Full Text
• Baginski L, Tewes F, Buckley ST, Healy AM, Bakowsky U, Ehrhardt C, Investigations on the fate of inhaled salmon calcitonin at the respiratory epithelial barrier, Pharmaceutical Research, 29, (1), 2012, p332-341Journal Article, 2012, DOI
• L DeMaio, ST Buckley, P Flodby, A Banfalvi, MS Krishnaveni, Y Xing, C Ehrhardt, P Minoo, ED Crandall, Z Borok, Transforming growth factor-β (TGF-β1) type I receptor mediates induction of epithelial-mesenchymal transition by type I collagen independent of TGF-β ligands, J Pathol, 226, (4), 2012, p633-644Journal Article, 2012, DOI
• ST Buckley, AM Davies, C Ehrhardt, Atomic force microscopy (AFM) and high-content analysis (HCA) - two innovative technologies for dissecting the relationship between epithelial-mesenchymal transition (EMT)-related morphological and structural alterations and cell mechanical properties, Methods Mol Biol , 784, 2011, p197-208Review, 2011
• MM Gaspar, A Radomska, OL Gobbo, MW Radomski, C Ehrhardt, Targeted delivery of transferrin-conjugated liposomes to an orthotopic model of lung cancer in nude rats, J Aerosol Med Pulm Drug Deliv, 25, (6), 2012, p310-318Journal Article, 2012, DOI
• Baginski L, Gobbo OL, Tewes F, Salomon JJ, Healy AM, Bakowsky U, Ehrhardt C, In vitro and in vivo characterisation of PEG-lipid based micellar complexes of salmon calcitonin for pulmonary delivery, Pharm Res, 29, (6), 2012, p1425-1434Journal Article, 2012, DOI
• F Májer, JJ Salomon, R Sharma, SV Etzbach, MNM Najib, R Keaveny, A Long, J Wang, C Ehrhardt, JF Gilmer, New fluorescent bile acids: Synthesis, chemical characterization, and disastereoselective uptake by Caco-2 cells of 3-deoxy 3-NBD-amino deoxycholic and ursodeoxycholic acid, Bioorg Med Chem, 20, (5), 2012, p1767-1778Journal Article, 2012, DOI , URL , TARA - Full Text
• JJ Salomon, C Ehrhardt, Regional distribution of organic cation transporters in human lung: possible therapeutic implications in aerosol therapy, Respiratory Drug Delivery, Respiratory Drug Delivery 12, Phoenix, AZ, 13-17/05/2012, 1, 2012, pp73-80Conference Paper, 2012
• Paszko E, Ehrhardt C, Senge MO, Kelleher DP, Reynolds JV, Nanodrug applications in photodynamic therapy., Photodiagnosis and photodynamic therapy, 8, (1), 2011, p14-29Journal Article, 2011, DOI , TARA - Full Text
• Tewes F, Gobbo OL, Amaro MI, Tajber L, Corrigan OI, Ehrhardt C, Healy AM, Evaluation of HPβCD-PEG microparticles for salmon calcitonin administration via pulmonary delivery, Molecular Pharmaceutics, 8, (5), 2011, p1887 - 1898Journal Article, 2011, DOI
• JJ Salomon, S Endter, G Tachon, F Falson, ST Buckley, C Ehrhardt, Transport of the fluorescent organic cation 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide (ASP+) in human respiratory epithelial cells, Eur J Pharm Biopharm, 81, (2), 2012, p351-359Journal Article, 2012, DOI , URL , TARA - Full Text
• JJ Salomon, C Ehrhardt, Organic cation transporters in the blood-air barrier: Expression and implications for pulmonary drug delivery, Ther Deliv, 3, (6), 2012, p735-747Review Article, 2012, DOI
• B Zhou, ST Buckley, V Patel, Y Liu, J Luo, MS Krishnaveni, M Ivan, L DeMaio, KJ Kim, C Ehrhardt, ED Crandall, Z Borok, Troglitazone attenuates TGF-β1-induced EMT in alveolar epithelial cells via a PPARγ-independent mechanism, PLoS ONE, 6, (7), 2012, pe38827Journal Article, 2012, DOI , TARA - Full Text
• N Chadderton, A Palfi, S Millington-Ward, O Gobbo, N Overlack, M Carrigan, M O'Reilly, M Campbell, C Ehrhardt, U Wolfrum, P Humphries, PF Kenna, GJ Farrar, Intravitreal delivery of AAV-NDI1 provides functional benefit in a murine model of Leber hereditary optic neuropathy, Eur J Hum Genet, 21, (1), 2013, p62-68Journal Article, 2013, DOI
• OL Gobbo, M Zurek, F Tewes, C Ehrhardt, Y Crémillieux, Manganese: a new contrast agent for lung imaging?, Contrast Media Mol I, 7, (6), 2012, p542-546Journal Article, 2012, DOI , TARA - Full Text
• E Paszko, GM Vaz, C Ehrhardt, MO Senge, Transferrin conjugation does not increase the efficiency of liposomal Foscan during in vitro photodynamic therapy of oesophageal cancer, European Journal of Pharmaceutical Sciences, 48, (1-2), 2013, p202-210Journal Article, 2013, DOI , TARA - Full Text
• J Swaminathan, C Ehrhardt, Liposomal delivery of proteins and peptides, Expert Opin Drug Deliv, 9, (12), 2012, p1489-503Review Article, 2012, DOI
• Tewes F, Paluch KJ, Tajber L, Gulati K, Kalantri D, Ehrhardt C, Healy AM, Steroid/mucokinetic hybrid nanoporous microparticles for pulmonary drug delivery, European Journal of Pharmaceutics and Biopharmaceutics, 85, (3), 2013, p604 - 613Journal Article, 2013, DOI , TARA - Full Text
• JJ Salomon, C Ehrhardt, KI Hosoya, The verapamil transporter in human alveolar epithelial cells (A549) does not interact with β2-receptor agonists, Drug Metabolism and Pharmacokinetics, 29, (1), 2014, p101-104Journal Article, 2014, DOI , TARA - Full Text
• JJ Salomon, P Galeron, N Schulte, PR Morow, D Severynse-Stevens, H Huwer, N Daum, CM Lehr, AJ Hickey, C Ehrhardt, Biopharmaceutical in vitro characterisation of CPZEN-45, a candidate compound for inhalation therapy of tuberculosis, Therapeutic Delivery, 4, (8), 2013, p915-923Journal Article, 2013, DOI
• Swaminathan J, Gobbo OL, Tewes F, Healy AM, Ehrhardt C, Encapsulation into PEG-liposomes does not improve the bioavailability of pulmonary delivered salmon calcitonin, Journal of Aerosol Medicine and Pulmonary Drug Delivery, 27, (1), 2014, p1-11Journal Article, 2014, DOI
• F Tewes, C Ehrhardt, AM Healy, Superparamagnetic iron oxide nanoparticles (SPIONs)-loaded Trojan microparticles for targeted aerosol delivery to the lung, Eur J Pharm Biopharm, 86, (1), 2014, p98-104Journal Article, 2014, DOI , TARA - Full Text
• C Ehrhardt, Why do we know so little about absorption pathways in the lung?, Inhalation, 8, (2), 2014, p27-28Journal Article, 2014, TARA - Full Text
• JJ Salomon, VE Muchitsch, JC Gausterer, E Schwagerus, H Huwer, N Daum, CM Lehr, C Ehrhardt, The cell line NCI-H441 is a useful in vitro model for transport studies of human distal lung epithelial barrier, Mol Pharm, 11, (3), 2014, p995-1006Journal Article, 2014, DOI
• J Swaminathan, C Ehrhardt, Effect of lyophilisation on liposomal systems for the delivery of salmon calcitonin (sCT), J Liposome Res, 24, (4), 2014, p297-303Journal Article, 2014, DOI , TARA - Full Text
• JN Seheult, P O'Connell, I Sulaiman, KC Tee, T Bholah, E MacHale, S D'Arcy, MS Holmes, G Crispino-O'Connell, RB Reilly, D Bergin, E Reeves, C Ehrhardt, AM Healy, RW Costello, An acoustic method for monitoring aerosol delivery from a DiskusTM dry powder inhaler, Pharm Res, 31, (10), 2014, p2735-2747Journal Article, 2014, DOI
• MS Holmes, JN Seheult, P O'Connell, S D'Arcy, C Ehrhardt, AM Healy, RW Costello, RB Reilly, An acoustic based method to detect and quantify the effect of exhalation into a dry powder inhaler, J Aerosol Med Pulm Drug Deliv, 28, (4), 2015, p247-253Journal Article, 2015, DOI
• X Hu, FF Yang, LH Quan, CY Liu, XM Liu, C Ehrhardt, YH Liao, Pulmonary delivered polymeric micelles - pharmacokinetic evaluation and biodistribution studies, Eur J Pharm Biopharm, 88, (3), 2014, p1064-1075Journal Article, 2014, DOI , TARA - Full Text
• E Schwagerus, S Sladek, ST Buckley, N Armas-Capote, D Alvarez de la Rosa, BJ Harvey, H Fischer, B Illek, H Huwer, N Daum, CM Lehr, C Ehrhardt, Expression and function of the epithelial sodium channel δ-subunit in human respiratory epithelial cells in vitro, Pflug Arch Eur J Phy, 467, (11), 2015, p2257-2273Journal Article, 2015, DOI

• C Ehrhardt, Drug transporters in the lung and it their relevance for pulmonary drug disposition, Universitetet i Tromsø, Institutt for farmasi, Tromsø, Norway, 19/03/2015, 2015Invited Talk
• C Ehrhardt, In vitro, ex vivo and in vivo models for pulmonary drug disposition studies, AstraZeneca, Mölndal, Sweden, 25/03/2015, 2015Invited Talk
• C Ehrhardt, The impact of membrane transporters on drug absorption from the lungs, AstraZeneca, Mölndal, Sweden, 25/03/2015, 2015Invited Talk
• C Ehrhardt, S Nickel, MA Selo, CG Clerkin, JJ Salomon, B Talbot, JJ Walsh, OCTN1-mediated ergothioneine uptake protects lung epithelial cells from tobacco smoke-induced damage, FASEB J, Experimental Biology Meeting 2015, Boston, MA, 28/03-01/04/2015, 29, 2015, pp970.7Meeting Abstract
• C Ehrhardt, OCTN1-mediated ergothioneine uptake protects lung epithelial cells from tobacco smoke-induced damage, Experimental Biology Meeting 2015, Boston, MA, 31/03/2015, 2015Invited Talk
• C Ehrhardt, The role of drug transporters in inhalation biopharmaceutics, University of Toyama. Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan, 13/04/2015, 2015Invited Talk
• C Ehrhardt, Drug transporters in the lung - expression and interactions with inhaled medicines, Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan, 15/04/2015, 2015Invited Talk
• C Ehrhardt, Arzneistoffabsorption in der Lunge - mehr als nur Diffusion, Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle (Saale), Germany, 24/03/2015, 2015Invited Talk
• C Ehrhardt, Ergothioneine protects lung epithelial cells from tobacco smoke-induced oxidative damage, 14th Symposium of the Flight Attendant Medical Research Institute, Miami, FL, 15/05/2015, 2015Invited Talk
• JJ Salomon, C Ehrhardt, Organic cation transporter function in different in vitro models of human lung epithelium, AAPS/ITC Joint Workshop on Drug Transporters, Baltimore, MD, 20-22/04/2015, 2015, ppM1001Meeting Abstract
• VE Muchitsch, C Ehrhardt, NCI-H441 human bronchiolar epithelial cells functionally express P-glycoprotein and multidrug resistance-related protein-1, AAPS/ITC Joint Workshop on Drug Transporters, Baltimore, MD, 20-22/04/2015, 2015, ppM1002Meeting Abstract
• S Nickel, MA Selo, CG Clerkin, JJ Salomon, BN Talbot, JJ Walsh, C Ehrhardt, Ergothioneine uptake by OCTN1 protects lung epithelial cells from tobacco smoke-induced damage, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2015, Denver, CO, 15-20/05/2015, 191, 2015, ppA2048Meeting Abstract
• C Ehrhardt, Importance of Aerosol Drug Distribution I: Drug Uptake: What are the Cellular Targets and Their Locations in the Respiratory Tract? , 20th Congress of the International Society for Aerosols in Medicine, München, Germany, 30/05/2015, 2015Invited Talk
• VE Muchitsch, C Ehrhardt, P-glycoprotein and multidrug resistance-related protein 1 are functionally expressed in the human distal lung epithelial cell line NCI-H441, J Aerosol Med Pulm Drug Deliv, 20th Congress of the International Society for Aerosols in Medicine, München, Germany, 30/05-03/06/2015, 28, (3), 2015, ppA27Meeting Abstract
• M Ortiz, MA Martins, A Pohlmann, A Bernardi, S Guterres, C Ehrhardt, Dry powders inhalers from budesonide loaded lipid-core nanocapsules for asthma treatment: development and toxicity evaluation, J Aerosol Med Pulm Drug Deliv, 20th Congress of the International Society for Aerosols in Medicine, München, Germany, 30/05-03/06/2015, 28, (3), 2015, ppA25Meeting Abstract
• S Nickel, MA Selo, CG Clerkin, JJ Salomon, M Ortiz, E Richert, BN Talbot, JJ Walsh, C Ehrhardt, Ergothioneine protects lung epithelial cells from tobacco smoke-induced oxidative damage, 3rd COST BM1201 Conference on the Early Origins of Chronic Lung Disease, Stockholm, Sweden, 15-16/06/2015, 2015Meeting Abstract
• C Ehrhardt, 2nd Workshop on Pulmonary Drug Delivery, 16-18/09/2015, 2015, Trinity College DublinMeetings /Conferences Organised
• C Ehrhardt, The best of the rest - transporters in non-traditional biological barriers, 25-29/10/2015, In:29th Annual Meeting of the American Association of Pharmaceutical Scientists, 2015, Orlando, FLMeetings /Conferences Organised
• S Nickel, MA Selo, CG Clerkin, M Meinhardt, C Ehrhardt, Studies on the functional expression of MRP1 and BCRP in lung epithelial cells in vitro, AAPS J, 29th Annual Meeting of the AAPS, Orlando, FL, 25-29/10/2015, 17, (S2), 2015, ppW5247Meeting Abstract
• C Ehrhardt, Inhalation Biopharmaceutics - Do Transporters Matter in the Lung? , 29th Annual Meeting of the AAPS, Orlando, FL, 29/10/2015, 2015Invited Talk
• C Ehrhardt, Recent advances in drug transporter research in the lungs, Department of Pharmaceutics and Therapeutics, Graduate School of Biomedical & Health Sciences, Hiroshima University, Japan, 09/11/2015, 2015Invited Talk
• S Nickel, MA Selo, CG Clerkin, PR Reynolds, Y Kato, N Nakamichi, BN Talbot, JJ Walsh, C Ehrhardt, OCTN1-mediated uptake of ergothioneine protects from tobacco smoke-induced oxidative damage, 30th Annual Meeting of the Japanese Society for the Study of Xenobiotics, Tokyo, Japan, 12-14/11/2105, 2015, pp326Meeting Abstract
• S Nickel, MA Selo, CG Clerkin, M Meinhardt, C Ehrhardt, Expression and activity of MRP1 and BCRP in lung epithelial cells in vitro, 30th Annual Meeting of the Japanese Society for the Study of Xenobiotics, Tokyo, Japan, 12-14/11/2015, 2015, pp290Meeting Abstract
• C Ehrhardt, OCTN1-mediated uptake of ergothioneine protects from tobacco smoke-induced oxidative damage, 30th Annual Meeting of the Japanese Society for the Study of Xenobiotics, Tokyo, Japan, 2015Oral Presentation
• C Ehrhardt, Transport and efflux systems at the air-blood-barrier, 11th International Conference and Workshop on Biological Barriers, Saarbrücken, Germany, 08/03/2016, 2016Invited Talk
• C Ehrhardt, Membrane transporters in lung epithelial barrier, University of Southern California, School of Pharmacy, Los Angeles, CA, 01/04/2016, 2016Invited Talk
• C Ehrhardt, MA Selo, CG Clerkin, BN Talbot, JJ Walsh, JB Lewis, PR Reynolds, Y Kato, N Nakamichi, S Nickel, Protective role of ergothioneine from tobacco smoke-induced oxidative stress in vitro and in vivo, FASEB J, Experimental Biology Meeting 2016, San Diego, CA, Experimental Biology, 30, (4), 2016, pp982.1Meeting Abstract
• C Ehrhardt, Protective role of ergothioneine from tobacco smoke-induced oxidative stress in vitro and in vivo, Experimental Biology Meeting 2016, San Diego, CA, 04/04/2016, 2016Oral Presentation
• C Ehrhardt, CG Clerkin, MA Selo, J Fallack, S Nickel, Human distal lung epithelial cells express functional MRP1 and BCRP in vitro, AAPS/ITC Joint Workshop on Drug Transporters, Baltimore, MD, 18-20/04/2016, 2016, ppM1003Meeting Abstract
• C Ehrhardt, CG Clerkin, MA Selo, S Nickel, Protective effect of OCTN1-mediated ergothioneine uptake in lung epithelial cells in vitro and in vivo, AAPS/ITC Joint Workshop on Drug Transporters, Baltimore, MD, 18-20/04/2016, 2016, ppM1040Meeting Abstract
• S Nickel, MA Selo, CG Clerkin, BN Talbot, JJ Walsh, JB Lewis, PR Reynolds, Y Kato, N Nakamichi, C Ehrhardt, Ergothioneine protects lung epithelial cells from tobacco smoke-induced oxidative damage in vitro and in vivo, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2016, San Francisco, CA, 13-18/05/2016, 193, 2016, ppA7514Meeting Abstract
• C Ehrhardt, In vitro, ex vivo and in vivo evidence for drug transporter interactions in lung drug disposition , Department of Pharmaceutics and Therapeutics, Graduate School of Biomedical & Health Sciences, Hiroshima University, Japan, 31/05/2016, 2016Invited Talk
• C Ehrhardt, Involvement of membrane transporters in pulmonary drug disposition and their role in COPD, Department of Molecular Cell Physiology, Kyoto Prefectural University of Medicine, Kyoto, Japan, 01/06.2016, 2016Invited Talk
• C Ehrhardt, Drug transporters in the lungs - How do they contribute to pulmonary drug disposition? , Laboratory of Pharmaceutics, Osaka University of Pharmaceutical Sciences, Osaka, Japan, 03/06/2016, 2016Invited Talk
• C Ehrhardt, Biopharmazie der Lunge - Über das Schicksal inhalierter Arzneistoffe, Department für Pharmazeutische Technologie und Biopharmazie, Universität Wien, Wien, Austria, 10/06/2016, 2016Invited Talk
• C Ehrhardt, In vitro, ex vivo and in vivo models of the lungs, DNA-TRAP Workshop on Drug Development to Cross Biological Barriers, University of East Anglia, Norwich, UK, 30/06/2016, 2016Invited Talk
• S Nickel, MA Selo, CG Clerkin, BN Talbot, JJ Walsh, JB Lewis, DC Milner, PR Reynolds, Y Kato, N Nakamichi, C Ehrhardt, Ergothioneine protects lung epithelial cells from tobacco smoke-induced oxidative damage in vitro and in vivo, 15th Symposium of the Flight Attendant Medical Research Institute, Miami, FL, 23-25/05/2016, 2016Meeting Abstract
• S Nickel, MA Selo, CG Clerkin, Y Kato, PR Reynolds, C Ehrhardt, Ergothioneine up-regulates anti-oxidant enzymes and thus protects from tobacco smoke-related damage, Physiology 2016 - Joint Meeting of the American Physiological Society and The Physiological Society, Dublin, Ireland, 29-31/07/2016, 2016Meeting Abstract
• C Ehrhardt, Organic cation transporters in the lungs - their role in drug disposition and as drug targets, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil, 19/08/2016, 2016Invited Talk
• C Ehrhardt, Mechanisms of drug disposition in the lung, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil, 01/09/2016, 2016Invited Talk
• C Ehrhardt, The role of drug transporters in inhalation biopharmaceutics, 18th International Pharmaceutical Technology Symposium-IPTS 2016, Antalya, Turkey, 19/09/2016, 2016Invited Talk
• C Ehrhardt, 1st Workshop on Drug Transporters in the Lungs, 22-23/09/2016, 2016, Trinity College Dublin, Dublin, IrelandMeetings /Conferences Organised
• C Ehrhardt, Cell culture models of the air-blood barrier, 1st Workshop on Drug Transporters in the Lungs, Trinity College Dublin, Dublin, Ireland, 22/09/2016, 2016Invited Talk
• C Ehrhardt, Interaction of organic cation transporters with bronchodilators in vitro, ex vivo and in vivo, 1st Workshop on Drug Transporters in the Lungs, Trinity College Dublin, Dublin, Ireland, 22/09/2016, 2016Invited Talk
• C Ehrhardt, Pharmacokinetic and pathophysiological roles of transporters in the lung, Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan, 12/10/2016, 2016Invited Talk
• C Ehrhardt, Drug Transporters in the Lung, PhD Course on Biological Membranes, Drug Targets and Absorption Barriers, Copenhagen, Denmark, 01/11/2016, 2016Invited Talk
• C Ehrhardt, Einfluss von Transporterproteinen auf die Arzneistoffverteilung in der Lunge, XIX. Deutsches Aerosol Therapie Seminar, Schloss Waldeck, Germany, 05/11/2016, 2016Invited Talk
• MA Selo, M Richter, J Fallack, N Schneider-Daum, CM Lehr, S Nickel, C Ehrhardt, Multidrug resistance-associated protein 1 (MRP1) expression and activity in human distal lung epithelial cells, AAPS J, 30th Annual Meeting of the AAPS, Denver, CO, 13-17/11/2016, 18, (S2), 2016, pp05W0400Meeting Abstract
• C Ehrhardt, Innovative Formulierungen für die Inhalationstherapie mit Biopharmazeutika, Institut für Pharmazeutische Technologie, Technische Universität Braunschweig, Germany, 10/01/2017, 2017Invited Talk
• C Ehrhardt, Ergothioneine, OCTN1 and COPD, 36th Western Epithelial Biology Society Meeting, Avila Beach, CA, 04/03/2017, 2017Invited Talk
• C Ehrhardt, Organic cation transporters in the lung, Department of Molecular Pharmacology and Physiology, University of South Florida, Tampa, FL, 05/05/2017, 2017Invited Talk
• MA Selo, S Nickel, J Fallack, H Huwer, N Schneider-Daum, CM Lehr, C Ehrhardt, Determination of expression and activity of breast cancer resistance protein (BCRP/ABCG2) in human lung alveolar epithelial barrier in vitro, J Aerosol Med Pulm Drug Deliv, 21st Congress of the International Society for Aerosols in Medicine, Santa Fe, NM, 03-06/06/2017, 30, (3), 2017Oral Presentation
• C Ehrhardt, Organic cation transporter function in different in vitro lung epithelial models: impact on delivery of pharmaceuticals and chemicals., 53rd Congress of the European Societies of Toxicology (EUROTOX 2017), Bratislava, Slovakia, 10/09/2017, 2017Invited Talk
• C Ehrhardt, In vitro and ex vivo models to study inhalation biopharmaceutics - are we there yet? , Inhalation Asia 2017, Macau, China, 15/09/2017, 2017Invited Talk
• C Ehrhardt, Anatomy and cell physiology of the human lungs and in vitro and ex vivo models to study pulmonary drug disposition, 4th Pulmonary Drug Delivery Workshop, Istanbul, Turkey, 20/09/2017, 2017Invited Talk
• C Ehrhardt, Ayca Yildiz-Pekoz, 4th Pulmonary Drug Delivery Workshop, 19-21/2017, 2017, Istanbul, TurkeyMeetings /Conferences Organised
• C Ehrhardt, Das ABC der Membrantransporter in der Lunge - von der Absorption und Bioverfügbarkeit von Arzneistoffen zum Ursprung der Chronisch-Obstruktiven Lungenerkrankung, Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle (Saale), Germany, 02/11/2017, 2017Invited Talk
• CG Clerkin, M Matzinger, MA Selo, BN Talbot, JJ Walsh, C Ehrhardt, Nucleophilic substitution reactions of ergothioneine might be a novel xenobiotic deactivation mechanism, 32nd Annual Meeting of the Japanese Society for the Study of Xenobiotics, Tokyo, Japan, 29/11-01/12/2017, 2017Oral Presentation
• C Ehrhardt, Different roles of organic cation transporters in the lung - drug disposition and origins of pulmonary disease, Department of Clinical Pharmaceutics, Graduate School of Life Sciences, Hokkaido University, Sapporo, Japan, 04/12/2017, 2017Invited Talk
• C Ehrhardt, Functional expression of MRP1 in human distal lung epithelium and its interaction with inhaled drugs, 37th Western Epithelial Biology Society Meeting, Avila Beach, CA, 03/03/2018, 2018Invited Talk
• C Ehrhardt, OCTN1 and COPD - Is there a role for drug transporters in pulmonary disease?, 20. Bad Herrenalber Transporter- und Barrieretage, Bad Herrenalb, Germany, 08/05/2018, 2018Invited Talk
• C Ehrhardt, In vitro and ex vivo models for lung drug disposition and toxicity testing, 3rd Annual Inhalation & Respiratory Drug Delivery Congress, London, UK, 09/05/2018, 2018Invited Talk
• C Ehrhardt, 5th Workshop on Pulmonary Drug Delivery and SimInhale Summer School, 03-06/09/2018, 2018, Trinity College Dublin, Dublin, IrelandMeetings /Conferences Organised
• C Ehrhardt, Anatomy and physiology of the lung and aerosol inhalation basics, 5th Pulmonary Drug Delivery Workshop, Dublin, Ireland, 03/09/2018, 2018Invited Talk
• C Ehrhardt, Respiratory membrane transporters - from pulmonary drug disposition to the origins of inflammatory lung diseases, Universität Bern, Bern, Switzerland, 04/09/2018, 2018Invited Talk
• C Ehrhardt, In vitro and ex vivo models of the air-blood barrier, 5th Pulmonary Drug Delivery Workshop, Dublin, Ireland, 06/09/2018, 2018Invited Talk
• C Ehrhardt, Therapeutic fields: Inhaled vaccines, antibiotics, insulin and therapies for lung cancer, Inhalation and Respiratory Drug Products European Conference 2018, Barcelona, Spain, 21/09/2018, 2018Invited Talk
• C Ehrhardt, Drug transporters in the lung, PhD Course on Biological Membranes, Drug Targets and Absorption Barriers, Copenhagen, Denmark, 23/11/2018, 2018Invited Talk
• C Ehrhardt, Expression of MRP1 in human distal lung epithelium and its regulation by tobacco smoke and inhaled drugs in vitro, 2018 Meeting of The Southern Salt, Water and Kidney Club, Lido Key, FL, 06/12/2018 , 2018Invited Talk
• MA Selo, S Nickel, M Richter, CG Clerkin, C Ehrhardt, Characterisation of MRP1 in human distal lung epithelial cells in vitro, Drug Delivery to the Lungs 27, Edinburgh, UK, 07-09/12/2016, 2016Oral Presentation
• MA Selo, S Nickel, L Springer, CG Clerkin, M Richter, C Ehrhardt, Multidrug resistance-associated protein 1 (MRP1) is functionally expressed in human distal lung epithelial cells, 39th All-Ireland Schools of Pharmacy Conference, Cork, Ireland, 24-25/04/2017, 2017Meeting Abstract
• CG Clerkin, M Matzinger, MA Selo, BN Talbot, JJ Walsh, C Ehrhardt, Aromatic substitution reaction of ergothioneine - a novel mechanism of xenobiotic deactivation, FASEB J , Experimental Biology Meeting 2017, Chicago, IL, 22-26/04/2017, 31, (S1), 2017, pp821.1Meeting Abstract
• MA Selo, S Nickel, CG Clerkin, C Ehrhardt, Ergothioneine induces antioxidant enzymes in human lung epithelial cells in vitro, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2017, Washington, DC, 19-24/05/2017, 195, 2017, ppA6279Meeting Abstract
• A Yildiz Pekoz, O Akbal, S Sancar, MA Selo, CG Clerkin, S Nickel, C Ehrhardt, Ascorbic acid protects human lung epithelial cells in vitro from tobacco smoke-induced oxidative damage, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2017, Washington, DC, 19-24/05/2017, 195, 2017, ppA6299Meeting Abstract
• A Al-Hayali, MA Selo, C Ehrhardt, S Velaga, Investigation of supersaturation and permeation of a poorly water soluble drug ezetimibe, 6th FIP Pharmaceutical Sciences World Congress, Stockholm, Sweden, 21-24/05/2017, 2017Meeting Abstract
• MA Selo, L Springer, S Nickel, C Ehrhardt, Functional expression of MRP1 in human distal lung epithelium and its interaction with inhaled drugs in vitro, 9th annual AAPS Joint Workshop on Drug Transporters in ADME: From the Bench to the Bedside, Herndon, VA, 16-18/04/2018, 2018Meeting Abstract
• CG Clerkin, S Nickel, A Faiz, MA Selo, W Timens, N ten Hacken, M van den Berge, IH Heijink, J Keane, C Ehrhardt, The organic cation transporter novel 1 (OCTN1) may be a novel factor in the development of COPD, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2018, San Diego, CA, 18-23/05/2018, 197, 2018, ppA7124Meeting Abstract
• MA Selo, L Springer, S Nickel, AS Delmas, C Ehrhardt, Expression, activity and drug interactions of MRP1 in human distal lung epithelial cells in vitro, 12th International Symposium on Pharmaceutical Sciences (ISOPS), Ankara, Turkey, 26-29/06/2018, 2018Oral Presentation
• C Ehrhardt, West Coast Lung Epithelial Transport (and Karaoke) Symposium, 23/03/2019, 2019, Los Angeles, CAMeetings /Conferences Organised
• C Ehrhardt, Efflux transporters in the lung - friends or foes?, 1st International Conference on Pharmaceutical Sciences (ICPS), Kufa, Al-Najaf, Iraq, 24/04/2019, 2019Invited Talk
• C Ehrhardt, CC Koay, CG Clerkin, MA Selo, In vitro studies on the impact of ergothioneine on idiopathic pulmonary fibrosis markers in human lung epithelial cells, FASEB J, Experimental Biology Meeting 2019, Orlando, FL, 06-09/04/2019, 33, (S1), 2019, pp127.11-Oral Presentation
• MA Selo, L Springer, S Nickel, AS Delmas, C Ehrhardt, In vitro interactions of multidrug resistance-associated protein 1 (MRP1) with inhaled drugs and tobacco smoke, 1st International Conference on Pharmaceutical Sciences (ICPS), Kufa, Al-Najaf, Iraq, 24-25/04/2019, 2019Meeting Abstract
• CC Koay, MA Selo, CG Clerkin, C Ehrhardt, In vitro studies on the impact of ergothioneine on idiopathic pulmonary fibrosis markers in human lung epithelial cells, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2019, Dallas, TX, 17-22/05/2019, 199, 2019, ppA2142-Meeting Abstract
• C Ehrhardt, Inhaled Antibiotics: Current Strategies and Future Challenges, Inhaled Drug Delivery Summit 2019, Berlin, Germany, 23/05/2019, 2019Invited Talk
• C Ehrhardt, In vitro Models for Pulmonary Drug Disposition Studies, 22nd Congress of the International Society for Aerosols in Medicine, Montreux, Switzerland, 25/05/2019, 2019Invited Talk
• C Ehrhardt, Inhalation Biopharmaceutics: Progress towards comprehending the fate of inhaled medicines, Universidade Estadual de Campinas, Campinas, SP, Brazil, 12/02/2019, 2019Invited Talk
• C Ehrhardt, Role of transporter proteins in the lung - from drug disposition to origins of lung disease, University College Cork, Department of Physiology, Cork, Ireland, 14/03/2019, 2019Invited Talk
• C Ehrhardt, Inhalation Biopharmaceutics: Progress towards comprehending the fate of inhaled medicines, Teva Pharmaceuticals, Waterford, Ireland, 01/05/2019, 2019Invited Talk
• C Ehrhardt, 6th Pulmonary Drug Delivery Workshop, 11 - 13/09/2019, 2019, Istanbul, TurkeyMeetings /Conferences Organised, URL
• C Ehrhardt, Anatomy and physiology of the lung and aerosol inhalation basics, 6th Pulmonary Drug Delivery Workshop, Istanbul, Turkey, 11/09/2019, 2019, C Ehrhardt, A Yildiz-PekozInvited Talk
• C Ehrhardt, Efflux Transporters in the Lung, International Conference on Current Challenges and Future Opportunities for Inhalation Therapies, Athens, Greece, 02/10/2019, 2019Invited Talk
• C Ehrhardt, Is there a role for efflux transporters in pulmonary drug disposition? , National University of Singapore, Department of Pharmacy, Singapore, 25/10/2019, 2019Invited Talk
• C Ehrhardt, Lung membrane transporters in health and disease, University of Oklahoma Health Sciences Center, Department of Pharmaceutical Sciences, Oklahoma City, OK, 30/10/2019, 2019Invited Talk
• C Ehrhardt, C Kneuer, UF Schaefer, CM Lehr, Development of an in vitro model for drug absorption based on the bronchial epithelial cell line 16HBE14o - Proc CRS German Chapter Annual Meeting, Saarbrücken, Germany, 02.02.2001, 2001, pp4Meeting Abstract
• C Ehrhardt, B Amro, C Kneuer, UF Schaefer, KJ Kim, CM Lehr, Characterisation of the bronchial epithelial cell line 16HBE14o- as an in vitro model for drug absorption: expression of P-glycoprotein, LRP-56 and caveolin-1, Proc Intern Symp Control Rel Bioact Mat, 28th Annual Meeting of the Controlled Release Society, San Diego, CA, 23.-27.06.2001, 28, (1), 2001, pp203Meeting Abstract
• C Ehrhardt, J Fiegel, UF Schaefer, J Hanes CM Lehr, Calu-3 bronchial epithelial cell monolayers to study drug release and absorption from aerosol particles in vitro, Proc 4th World Meeting ADRITELF/APGI/APV, 4th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Firenze, Italy, 08.-11.04.2002, 2002, pp1009 - 1010Meeting Abstract
• C Ehrhardt, UF Schaefer, CM Lehr, Human alveolar epithelial cell monolayers in primary culture as an in vitro model for drug absorption studies, Proc 4th GPEN Meeting, 4th GPEN Meeting, Ann Arbor, MI, 06.-08.11.2002, 2002, pp37Meeting Abstract
• C Ehrhardt, C Bies, H Stumpf, C Kneuer, UF Schaefer, KJ Kim, CM Lehr, Active absorption of salbutamol across human respiratory epithelial cell layers, J Aerosol Med, International Society for Aerosols in Medicine 2003, Baltimore, MD, 14.-18.06.2003, 16, (2), 2003, pp214Meeting Abstract
• C Ehrhardt, C Bies, H Stumpf, C Kneuer, UF Schaefer, KJ Kim, CM Lehr, Salbutamol is actively absorbed across human respiratory epithelial cell layers, Proc Intern Symp Control Rel Bioact Mat, 30th Annual Meeting of the Controlled Release Society, Glasgow, United Kingdom, 19.-23.07.2003, 30, (1), 2003, pp95Meeting Abstract
• C Ehrhardt, M Bur, UF Schaefer, CM Lehr, KJ Kim, Bioelectric properties of primary cultured tight monolayers of human alveolar epithelial cells (hAEpC), FASEB J, Experimental Biology Meeting 2004, Washington, DC, 17.-21.04.2004, 18, (4), 2004, ppA723Meeting Abstract
• C Ehrhardt , In vitro Transportstudien über Epithelzellen der Lunge: Eine Methode zur Aufklärung von Absorptionsprozessen pulmonal applizierter Arzneistoffe, DPhG Doktorandentagung, Düsseldorf, Germany, 09.03.2003, 2003Invited Talk
• C Ehrhardt , Nanoparticles as carrier systems for drug delivery and gene therapy, 5th Course on Smart Materials and Nanotechnology, Università Politecnica delle Marche, Jesi (AN), Italy, 29.08.2003, 2003Invited Talk
• C Ehrhardt , Drug transport across the epithelium, 5th GUIDE/UIPS Course on Drug Delivery and Targetin, Rijksuniversiteit Groningen, Groningen, The Netherlands, 24.11.2003, 2003Invited Talk
• C Ehrhardt , Cell culture models of the human airway and alveolar epithelium, 5th International Conference and Workshop on Cell Culture and In Vitro Models for Drug Absorption and Delivery, Saarbrücken, Germany, 01.03.2004, 2004Invited Talk
• C Ehrhardt , The lung in a box - can pulmonary PK really be predicted from cell culture models?, EUFEPS 2004, Bruxelles, Belgium, 20.10.2004, 2004Invited Talk
• C Ehrhardt, The lung as a target for drug delivery: cell culture models as in vitro test systems, University of Malta, Msida, Malta, 27.10.2000, 2000Invited Talk
• C Ehrhardt, Bronchial epithelial cell culture as an in vitro model for drug absorption, Johns Hopkins University, Baltimore, MD, 28.08.2001, 2001Invited Talk
• C Ehrhardt , Development of in vitro models for studies on drug absorption and drug carrier-cell interactions based on human respiratory epithelial cells, Johns Hopkins University, Baltimore, MD, 22.08.2002, 2002Invited Talk
• C Ehrhardt , The use of respiratory epithelial cell models for drug absorption studies, Trinity College, Dublin, Ireland, 25.07.2003, 2003Invited Talk
• C Ehrhardt , Entwicklung und Charakterisierung von in vitro Modellen zur Arzneistoffabsorption und Partikel-Zell-Interaktion basierend auf Epithelzellkulturen der humanen Lunge, Institut für Inhalationsbiologie, GSF, München, Germany, 04.11.2003, 2003Invited Talk
• C Ehrhardt , Cell culture models of the human airway and alveolar epithelium, Seminars in Molecular Medicine, Royal College of Surgeon in Ireland, Dublin, Ireland, 10.09.2004, 2004Invited Talk
• C Ehrhardt , Insulintherapie im Wandel: Von injizierten zum inhalativen Hormon, Zentrales Institut des Sanitätsdienstes der Bundeswehr, Kiel, Germany, 26.10.2002, 2002Invited Talk
• C Ehrhardt , Zellkultursysteme als Werkzeug zur Vorhersage der Arzneistoffabsorption, Zentrales Institut des Sanitätsdienstes der Bundeswehr, Kiel, Germany, 24.03.2004, 2004Invited Talk
• C Ehrhardt , Verwendung von Zellkulturen des Lungenepithels als in vitro Modelle in der biopharmazeutischen Forschung, Symphatol Meeting, Saarbrücken, Germany, 14.05.2004, 2004Invited Talk
• C Ehrhardt , Human alveolar epithelial cell monolayers in primary culture for drug absorption and metabolism studies, Novo Nordisk A/S, Målov, Denmark, 29.04.2005, 2005Invited Talk
• N Demling, C Ehrhardt, M Kasper, M Laue, L Knels, KJ Kim, EP Rieber, RAGE, a marker for human alveolar type I cells promotes cell adhesion, FASEB J, Experimental Biology Meeting 2005 and XXXV International Congress of Physiological Sciences, San Diego, CA, 02.-06.04.2005, 19, (5), 2005, ppA1294Meeting Abstract
• M Bur, C Ehrhardt, KJ Kim, CM Lehr, Bioelectric properties of primary cultured tight monolayers of human alveolar epithelial cells, IX. Deutsches Aerosol Therapie Seminar, Nürnberg, Germany, 12.-13.11.2004, 2004Meeting Abstract
• U Becker, C Ehrhardt, UF Schaefer, KW Rupprecht, CM Lehr, Proteins of the multi-drug resistance in human corneal tissue, Proc Association for Research in Vision and Ophthalmology Annual Meeting, Association for Research in Vision and Ophthalmology Annual Meeting 2005, Fort Lauderdale, FL, 01.-05.05.2005, 2005, pp113Meeting Abstract
• M Bur, C Ehrhardt, KJ Kim, CM Lehr, Bioelectric properties of primary cultured tight monolayers of human alveolar epithelial cells (hAEpC), Arch Pharm Pharm Med Chem, DPhG Jahrestagung und Joint-Meeting 2004, Regensburg, Germany, 07.-09.10.2004, 337, 2004Meeting Abstract
• EM Collnot, C Ehrhardt, C Bies, UF Schaefer CM Lehr, The human bronchial epithelial cell line CFBE41o- as an in vitro model for cystic fibrosis studies, Arch Pharm Pharm Med Chem, DPhG Jahrestagung und Joint-Meeting 2004, Regensburg, Germany, 07.-09.10.2004, 337, 2004Meeting Abstract
• S Anabousi, U Bakowsky, M Laue, CM Lehr, C Ehrhardt, AFM as a novel tool to verify the presence of transferrin on liposomal surfaces, AAPS J, 18th Annual meeting of the AAPS, Baltimore, MD, 07.-11.11.2004, 2004, ppT3263Meeting Abstract
• EM Collnot, C Ehrhardt, C Bies, UF Schaefer, CM Lehr, Towards an in vitro model of cystic fibrosis epithelium: the human bronchial epithelial cell line CFBE41o - AAPS J, 18th Annual Meeting of the AAPS, Baltimore, MD, 07.-11.11.2004, 2004, ppW4270Meeting Abstract
• EM Collnot, C Bies, J Hyatt, L Navarro, K Edgar, UF Schaefer, C Ehrhardt, CM Lehr, Inhibition of P-glycoprotein by TPGS: influence of the PEG-chain length, AAPS J, Annual Meeting of the AAPS, Baltimore, MD, 07.-11.11.2004, 2004, ppT2234Meeting Abstract
• C Ehrhardt, C Kneuer, RK Majeti, H Bakowsky, C Olbrich, D Hoekstra, CM Lehr, U Bakowsky, Modern pharmaceutical-relevant non-viral gene transfection systems, German Bunsen Society for Physical Chemistry Annual Meeting, Dresden, Germany, 20.-22.05.2004, 2004Meeting Abstract
• H Bakowsky C Ehrhardt, C Kneuer, D Hoekstra, U Bakowsky, Surface-modified liposomes: stability and specific binding properties, German Bunsen Society for Physical Chemistry Annual Meeting, Dresden, Germany, 20.-22.05.2004 , 2004Meeting Abstract
• H Bakowsky, C Ehrhardt, C Kneuer, U Rothe, U Bakowsky, Antiadhesive surface coatings generated by covalent coupling of monomolecular tetraetherlipid films, German Bunsen Society for Physical Chemistry Annual Meeting, Dresden, Germany, 20.-22.05.2004 , 2004Meeting Abstract
• U Bakowsky, C Loehbach, C Ehrhardt, D Hoekstra, CM Lehr, Characterization of adhesion forces between living human endothelial cells and protein-coated implant surfaces by scanning force microscopy, 7th European Adhesion Conference - EURADH 2004, Freiburg, Germany, 05.-09.09.2004 , 2004Meeting Abstract
• U Rothe, C Ehrhardt, H Bakowsky, C Kneuer, MNV Ravi Kumar, U Bakowsky, Selectins - an emerging target for site specific drug delivery, Proc Intern Symp Control Rel Bioact Mat, 31st Annual Meeting of the Controlled Release Society, Honolulu, HI, 12.-16.06.2004, 31, (1), 2004Meeting Abstract
• C Ehrhardt, Academic-Industrial Partnerships in Pharmaceutical Sciences - Unleashing Potential for the Benefit of All., 1st International Conference on Pharmaceutical Sciences and Industry, Nsukka, Nigeria, 01/03/2020, 2020Invited Talk
• C Ehrhardt, Ergothioneine and its transporter OCTN1 - Role in COPD, 2nd International Conference on Pharmaceutical Sciences (ICPS-2020), Kufa, Al-Najaf, Iraq, delivered online, 17/06/2020, 2020Invited Talk
• C Ehrhardt, Take a deep breath - systemic drug delivery via the lungs, Inhalation and Respiratory Drug Delivery Conference 2020, Berlin, Germany, 11/09/2020, 2020Invited Talk
• C Ehrhardt, Efflux transporters in the lung, Online Workshop Advances in Drug Delivery and Formulations, Campinas, SP, Brazil, 19/10/2020, 2020Invited Talk
• S Anabousi, CM Lehr, C Ehrhardt, Transferrin-modified liposomes for treatment of lung cancer - binding and uptake studies using human lung epithelial cells, 17th Mountain/Sea Liposome Workshop, Oberjoch, Germany, 04.-08.04.2005, 2005Meeting Abstract
• S Anabousi, CM Lehr, C Ehrhardt, Binding and uptake of transferring-modified liposomes in lung epithelial cells, Proc CRS German Chapter Annual Meeting, CRS German Chapter Annual Meeting, Marburg, Germany, 15.03.2005, 2005, pp17Meeting Abstract
• C Ehrhardt, Novel approached for systemic drug delivery via the lungs, 4th Inhalation and Respiratory Drug Delivery Conference, Online, 26/02/2021, 2021Invited Talk
• U Bakowsky, C Kneuer, C Ehrhardt, RK Majeti, H Bakowsky, Selectins - an emerging target for site specific drug delivery, Proc Int Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, International Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Nürnberg, Germany, edited by 15.-18.03.2004 , 2004, pp757 - 758Meeting Abstract
• S Anabousi, U Bakowsky, UF Schaefer, CM Lehr, C Ehrhardt, Preparation and characterisation of DSPE-PEG-maleimide-modified liposomes for conjugation with receptor ligands for cell specific targeting, Proc Int Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, International Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Nürnberg, Germany, 15.-18.03.2004, 2004, pp787 - 788Meeting Abstract
• U Becker, C Ehrhardt, UF Schaefer, HJ Gukasyan, KJ. Kim, VHL Lee, CM Lehr, Targeting a topically administered drug to posterior compartments of the eye, Proc Int Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, International Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Nürnberg, Germany, 15.-18.03.2004, 2004, pp857 - 858Meeting Abstract
• U Becker, C Ehrhardt, UF Schaefer, HJ Gukasyan, KJ. Kim, VHL Lee, CM Lehr, Determination of the tissue distribution of moxaverine-hydrochloride with special focus on the posterior compartments of the eye, Proc CRS German Chapter Annual Meeting, CRS German Chapter Annual Meeting, Heidelberg, Germany, 02.04.2004, 2004, pp17Meeting Abstract
• H Bakowsky, C Ehrhardt, C Kneuer, U Rothe, U Bakowsky, PEG-modified immunoliposomes for site-specific selectin targeting, Proc CRS German Chapter Annual Meeting, CRS German Chapter Annual Meeting, Heidelberg, Germany, 02.04.2004, 2004, pp7Meeting Abstract
• S Anabousi, U Bakowsky, M Laue, CM Lehr, C Ehrhardt, Atomic force microscopy and transmission electron microscopy are novel tools used for verification of transferrin modification of liposomes, Proc CRS German Chapter Annual Meeting, CRS German Chapter Annual Meeting, Heidelberg, Germany, 02.04.2004, 2004, pp16Meeting Abstract
• C Ehrhardt, EM Collnot, C Bies, UF Schaefer, KJ Kim, CM Lehr, Characterisation of the human cell line CFBE41o- as an in vitro model of cystic fibrotic bronchial epithelium, FASEB J, Experimental Biology Meeting 2004, Washington, DC, 17.-21.04.2004, 18, (5), 2004, ppA1052Meeting Abstract
• U Becker, C Ehrhardt, UF Schaefer, HJ Gukasyan, KJ. Kim, VHL Lee, CM Lehr, Tissue distribution and relative bioavailability of ocularly-administered moxaverine-HCl, Proc Association for Research in Vision and Ophthalmology Annual Meeting, Association for Research in Vision and Ophthalmology Annual Meeting, Fort Lauderdale, FL, 25.-29.04.2004, 2004, pp165Meeting Abstract
• C Ehrhardt, E Collnot, C Bies, UF Schaefer, CM Lehr, Characterisation of the human cell line CFBE41o- as an in vitro model of cystic fibrotic bronchial epithelium, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society, Orlando, FL, 21.-26.05.2004, 169, (7), 2004, ppA387Meeting Abstract
• C Ehrhardt, M Bur, CM Lehr, U Bakowsky, KJ Kim, Tight monolayers of human alveolar epithelial cells in primary culture: bioelectric properties, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society, Orlando, FL, 21.-26.05.2004, 169, (7), 2004, ppA670Meeting Abstract
• S Fuchs, C Ehrhardt, J Neumannová, UF Schaefer, CM Lehr, Human alveolar epithelial cell monolayers in primary culture - characterisation and drug transport, Proc Aerosols and Health, Aerosols and Health, Karlsruhe, Germany, 28.-29.06.2000, 2000, pp12Meeting Abstract
• C Ehrhardt, J Neumannová, UF Schaefer, CM Lehr, Human alveolar epithelial cell (hAEpC) monolayers in primary culture as an in vitro model for drug transport, Eur J Pharm Sci, 6th European Congress of Pharmaceutical Sciences, EUFEPS 2000, Budapest, Hungary, 16.-19.09.2000, 11, (S1), 2000, ppS90Meeting Abstract
• C Ehrhardt, S Fuchs, UF Schaefer, CM Lehr, Comparative evaluation of in vitro test systems for pulmonary drug delivery based on airway epithelial cell lines and human alveolar epithelial cells (hAEpC) in primary culture, ALTEX, 9. Österreichischer internationaler Kongreß über Ersatz- und Ergänzungsmethoden zu Tierversuchen in der biomedizinischen Forschung, Linz, Austria, 24.-26.09.2000, 18, (1), 2001, pp66Meeting Abstract
• J Moebius, C Ehrhardt, I Erler, UF Schaefer, CM Lehr, The epithelial cancer cell line Calu-3: Characterisation as an in vitro model for drug absorption in the upper airways, Arch Pharm Pharm Med Chem, 3rd European Graduate Student Meeting, Frankfurt, Germany, 23.-25.02.2001, 334, (S1), 2001, pp13Meeting Abstract
• J Fiegel, C Ehrhardt, CM Lehr, J Hanes, Air-interfaced lung epithelial cell monolayers for characterization of large light polymer aerosols, Ann Biomed Eng, Biomedical Engineering Society's Conference, Durham, NC, 04.-07.10.2001, 29, (S1), 2001, ppS141Meeting Abstract
• J Fiegel, C Ehrhardt, CM Lehr, J Hanes, An in vitro method to characterize therapeutic aerosol particulates using lung epithelial cell monolayers, Proc Am Inst Chem Eng, Annual Meeting of the AIChE, Reno, NV, 04.-09.11.2001, 2001Meeting Abstract
• C Ehrhardt, J Moebius, UF Schaefer, CM Lehr, Calu-3: Characterisation of an human bronchial cell line as an in vitro model for drug absorption in the upper airways, Proc 4th Workshop on Cell Culture and In Vitro Models for Drug Absorption and Delivery, 4th Workshop on Cell Culture and In Vitro Models for Drug Absorption and Delivery, Saarbrücken, Germany, 20.02.-01.03.2002, 2002Meeting Abstract
• U Bakowsky, H Bakowsky, G Bendas, U Rothe, C Ehrhardt, CM Lehr, D Hoekstra, The morphology dependence of the selectin/glycolipid recognition in lateral structured supported model membranes, Proc Nanobiotec II, Nanobiotec II, Marburg, Germany, 21.-25.09.2002, 2002, pp16Meeting Abstract
• U Bakowsky, H Bakowsky, C Kneuer, G Bendas, U Rothe, C Ehrhardt, CM Lehr, D Hoekstra, On the dependence of membrane morphology from selectin/glycolipid recognition properties, Arch Pharm Pharm Med Chem, Annual Meeting of the DPhG, Berlin, Germany, 09.-12.10.2002, 335, (S1), 2002, pp50Meeting Abstract
• C Ehrhardt, UF Schaefer, CM Lehr, Human alveolar epithelial cell monolayers in primary culture as an in vitro model for drug absorption studies, AAPS Pharm Sci, 16th Annual Meeting of the AAPS, Toronto, Canada, 10.-14.11.2002, 4, 2002, ppR6144Meeting Abstract
• U Bakowsky, C Loehbach, C Kneuer, C Ehrhardt, D Hoekstra, CM Lehr, The determination of adhesion forces between living cells and proteins by using scanning force microscopy, Proc CRS German Chapter Annual Meeting, CRS German Chapter Annual Meeting, München, Germany, 04.04.2003, 2003, pp37Meeting Abstract
• C Ehrhardt, C Bies, H Stumpf, C Kneuer, UF Schaefer, KJ Kim, CM Lehr, Net active absorption of salbutamol across human respiratory epithelial cell layers may occur via hOCT, Proc CRS German Chapter Annual Meeting, CRS German Chapter Annual Meeting, München, Germany, 04.04.2003, 2003, pp36Meeting Abstract
• C Ehrhardt, CM Lehr, Z Borok, ED Crandall, KJ Kim, Relative total ion conductance of the paracellular pathway in primary rat alveolar epithelial cells (AEC) monolayers, FASEB J, Experimental Biology Meeting 2003, San Diego, CA, 11.-15.04.2003, 17, (4), 2003, ppA85Meeting Abstract
• U Bakowsky, C Loehbach, C Kneuer, C Ehrhardt, D Hoekstra, CM Lehr, Determination of adhesion forces between nanosensors modified with living cells and protein-coated surfaces by scanning force microscopy, Proc Intern Symp Control Rel Bioact Mat, 30th Annual Meeting of the Controlled Release Society, Glasgow, United Kingdom, 19.-23.07.2003, 30, (1), 2003, pp787Meeting Abstract
• S Anabousi, U Bakowsky, U Schaefer, CM Lehr, C Ehrhardt, Design of DSPE-PEG-maleimide-modified liposomes for specific conjugation with transferrin, Proc 3rd Int Course Liposome Technol, 3rd International Galenos Intensive Course and Workshop on Liposome Technology and Applications in Therapeutics, Patras, Greece, 01.-11.09.2003, 2003, pp163Meeting Abstract
• C Ehrhardt, C Bies, H Stumpf, C Kneuer, UF Schaefer, KJ Kim, CM Lehr, Net active absorption of salbutamol across human respiratory epithelial cell layers may occur via hOCT, VIII. Deutsches Aerosol Therapie Seminar, Marburg, Germany, 14.-15.11.2003, 2003Meeting Abstract
• C Ehrhardt, J Fiegel, U Bakowsky, UF Schaefer, J Hanes, CM Lehr, Microparticle impingement on lung epithelial cell monolayers: Toward improved particle characterisation in the lung, VIII. Deutsches Aerosol Therapie Seminar, Marburg, Germany, 14.-15.11.2003, 2003Meeting Abstract
• C Ehrhardt, Current Trends and Future Challenges of Pulmonary Delivery to the Systemic Circulation, Oxford Global Formulation & Delivery Europe: ONLINE, 20/04/2021, 2021Invited Talk
• C Ehrhardt, Using the inhalation route to deliver drugs to the systemic circulation, Annual Inhaled Drug Delivery Summit 2021, Online, 05/08/2021, 2021Invited Talk
• C Ehrhardt, Systemic Drug Delivery by Inhalation - Lessons Learned and Future Prospects, 7th Inhalation & Respiratory Delivery Congress, London, UK, 21/09/2021, 2021Invited Talk
• C Ehrhardt, Beyond diffusion - elucidating absorption mechanisms at the air-blood barrier, LIVe 2022, Life in vitro event for innovative and predictive models, Nice, France, 14/06/2022, 2022Invited Talk
• C Ehrhardt, Systemic Drug Delivery by Inhalation, 3rd Inhalation and Respiratory Drug Delivery Conference 2022, Berlin, Germany, 08/09/2022, 2022Invited Talk
• C Ehrhardt, Biopharmaceutics of ABC-Transporters in the Lung, Department für Pharmazeutische Technologie und Biopharmazie, Universität Wien, Austria, 30/05/2022, 2022Invited Talk
• C Ehrhardt, The particle has landed - what happens to inhaled drugs after deposition? , Research Center for Pharmaceutical Engineering (RCPE), Graz, Austria, 08/06/2022, 2022Invited Talk
• C Ehrhardt, Cell culture models of biological barriers - lung epithelium, Proc Intern Symp Control Rel Bioact Mat, 32nd Annual Meeting of the Controlled Release Society, Miami Beach, FL, 18.-22.06.2005, 32, (1), 2005, pp130Meeting Abstract
• S Anabousi, CM Lehr, C Ehrhardt, Design of transferrin-modified liposomes: binding and uptake in lung cancer cells, Proc Intern Symp Control Rel Bioact Mat, 32nd Annual Meeting of the Controlled Release Society, Miami Beach, FL, 18.-22.06.2005, 32, (1), 2005, pp290Meeting Abstract
• C Ehrhardt , Cell culture models of biological barriers - lung epithelium, 32nd Annual meeting of the Controlled Release Society, Miami Beach, FL, 22.06.2005, 2005Invited Talk
• C Ehrhardt, Systemic Drug Delivery by Inhalation, 3rd Inhalation and Respiratory Drug Delivery Conference 2022, Berlin, Germany, 08/09/2022, 2022Invited Talk
• C Ehrhardt, MRP1's role in pulmonary drug absorption - a never ending story?, 4th International Conference on Pharmaceutical Sciences (ICPS), Kufa, Iraq, 16/03/2023, 2023Invited Talk
• C Ehrhardt, Deciphering absorption pathways in the lung - Involvement of ABC transporters, Dipartimento di Scienze Della Vita e Biotecnologie, Università Degli Studi Di Ferrara, Ferrara, Italy, 21/11/2022, 2022Invited Talk
• C Ehrhardt, Elucidating the contribution of ABC efflux transporters in the lung to health and disease, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki, Japan, 04/11/2022, 2022Invited Talk
• C Ehrhardt, Pulmonary drug delivery, 7th ULLA Summer School, Uppsala, Sweden, 08.07.2005, 2005Invited Talk
• C Ehrhardt, Systemic pulmonary drug delivery, 8th Pulmonary Drug Delivery Workshop, Istanbul, Türkiye, 31/05/2023, 2023Invited Talk
• C Ehrhardt, Von hinten durch die Brust in"s Auge - Systemische Therapie per Inhalation, 5. Jahrestagung ARKOS, Papenburg, Germany, 15/06/2023, 2023Invited Talk
• C Ehrhardt, In vitro and ex vivo models for inhalation biopharmaceutical studies, 2nd INNOVATRIX Respiratory Drugs Summit: Formulation & Drug Delivery, Prague, Czechia, 06/10/2023, 2023Invited Talk
• C Ehrhardt, Absorption pathways in the lungs, MVIC Symposium 2023, Lund, Sweden, 11/10/2023, 2023Invited Talk
• C Ehrhardt, Chancen und Herausforderungen für inhalierte Biotherapeutika - Perspektiven für inhalierte Biologika, XXIV. Deutsches Aerosol Therapie Symposium, München, Germany, 10/11/2023, 2023Invited Talk
• C Ehrhardt, Inhaled medicines development, The Association of Inhalation Toxicologists Pre-clinical development " Back to Basics Workshop at DDL2023, Edinburgh, UK, 06/12/2023, 2023Invited Talk
• C Ehrhardt, Drug absorption mechanisms in the lung " beyond passive diffusion, Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Hannover, Germany, 10/05/2023, 2023Invited Talk
• C Ehrhardt, Rethinking Pulmonary Drug Delivery, Center for Convergent Bioscience and Medicine (CCBM), University of Alabama, Tuscaloosa, AL, 19/10/2023, 2023Invited Talk
• C Ehrhardt, The impact of lung epithelial transporters on pulmonary drug delivery, 14th PBP World Meeting 2024, Wien, Austria, 21/03/2024, 2024Invited Talk
• C Ehrhardt, Net absorption of albuterol across bronchial epithelial cell layers, Sepracor Scientific Research Forum, Boston, MA, 30.09.2005, 2005Invited Talk
• S Endter, C Ehrhardt, CM Lehr, P Buckland, M Gumbleton, RT-PCR analysis of drug transporters in human lung epithelial cell models, AAPS J, 19th Annual Meeting of the AAPS, Nashville, TN, 06.11.-10.11.2005, 7, (S2), 2005, ppR6244Meeting Abstract
• M Bur, CM Lehr, N Hagen, M Guldbrandt, C Ehrhardt, Assessment of protein transport rates across human alveolar epithelial cell layers, AAPS J, 19th Annual Meeting of the AAPS, Nashville, TN, 06.11.-10.11.2005, 7, (S2), 2005, ppT2142Meeting Abstract
• C Kneuer, MNV Ravi Kumar, CM Lehr, T Kissel, C Ehrhardt, U Bakowsky, Novel nanoscale drug delivery systems, Proc BioNanoMaT, Bioinspired Nanomaterials for Medicine and Technologies, Marl, Germany, 23.-24.11.2005, 2005, pp45Meeting Abstract
• S Endter, CM Lehr, P Buckland, M Gumbleton, C Ehrhardt. , Expression of drug transporter mRNA in human lung epithelial cell models, 6th International Conference and Workshop on Cell Culture and in vitro Models for Drug Absorption and Delivery, Saarbrücken, Germany, 01.03.-10.03.2006, 2006Meeting Abstract
• U Becker, C Ehrhardt, UF Schaefer, KW Ruprecht, CM Lehr, Proteins of the multi-drug resistance in human corneal tissue, 6th International Conference and Workshop on Cell Culture and in vitro Models for Drug Absorption and Delivery, Saarbrücken, Germany, 01.03.-10.03.2006, 2006Meeting Abstract
• C Ehrhardt, M Bur, N Hagen, M Guldbrandt, H Huwer, CM Lehr, KJ Kim, Net absorption of serum proteins across primary human alveolar epithelial cell (hAEpC) monolayers., FASEB J, Experimental Biology Meeting 2006, San Francisco, CA, 01.-05.04.2006, 20, (5), 2006, ppA1438Meeting Abstract
• C Ehrhardt, C Kneuer, C Baldes, KJ Kim, CM Lehr, Albuterol is net absorbed across human alveolar epithelial cell monolayers, Proc Am Thor Soc , Annual Meeting of the American Thoracic Society 2006, San Diego, CA, 19.-24.05.2006, 3, 2006, ppA761Meeting Abstract
• C Ehrhardt, Drug delivery across pulmonary biological barriers, 8th International Symposium on Pharmaceutical Sciences, Ankara, Turkey, 13.06.2006, 2006Invited Talk
• C Ehrhardt, In vitro models of the lung, 3rd Socrates Intensive Programme: Innovative Therapeutics - From Molecules to Medicines, Athens, Greece, 05.07.2006, 2006Invited Talk
• C Ehrhardt, Prediction of pulmonary pharmacokinetics using in vitro models of the lung, 3rd Socrates Intensive Programme: Innovative Therapeutics - From Molecules to Medicines, Athens, Greece, 05.07.2006, 2006Invited Talk
• C Ehrhardt, Drug absorption via the respiratory tract - challenges and opportunities, Jordan University, Amman, Jordan, 19.07.2005, 2005Invited Talk
• C Ehrhardt, Drug absorption and metabolism in the lung - the impact of cell-based in vitro models, Jordan University, Amman, Jordan, 25.07.2005, 2005Invited Talk
• C Ehrhardt, Liposomal Drug Delivery - new strategies for the treatment of cancer and inflammation, Jordan University, Amman, Jordan, 26.07.2005, 2005Invited Talk
• C Ehrhardt, Drug absorption across human lung alveolar epithelial barrier, Nektar Therapeutics, San Carlos, CA, 31.07.2006, 2006Invited Talk
• C Ehrhardt, Drug absorption across human bronchial and alveolar epithelial barriers, University of Southern California, Los Angeles, CA, 03.08.2006, 2006Invited Talk
• C Ehrhardt, Drug absorption across human respiratory epithelial barriers, Pfizer, La Jolla, CA, 11.08.2006, 2006Invited Talk
• S Anabousi, E Kleemann, U Bakowsky, CM Lehr, C Ehrhardt, Transferrin-modified liposomes for inhalation therapy of lung can, Proc Intern Symp Control Rel Bioact Mat, 33rd Annual Meeting of the Controlled Release Society, Wien, Austria, 22.-26.07.2006, 33, (1), 2006, pp35Meeting Abstract
• S Anabousi, U Bakowsky, E Kleemann, CM Lehr, C Ehrhardt, Liposomal drug carrier systems for inhalation therapy of lung cancer, AAPS J, 20th Annual Meeting of the AAPS, San Antonio, TX, 28.10.-02.11.2006, 8, (S2), 2006, ppT2099Meeting Abstract
• S Endter, M Gumbleton, C Ehrhardt, RT-PCR analysis of ABC- and SLC-transporter expression in human respiratory epithelial cells, AAPS Workshop Drug Transporters in ADME: From the Bench to the Bedside, Bethesda, MD, 05.-07.03.2007, 2007, ppM1028Meeting Abstract
• U Becker, C Ehrhardt, UF Schaefer, CM Lehr, Comparison and evaluation of different models of the corneal epithelium with focus on ocular drug delivery, 3rd Pharmaceutical World Sciences Congress, Amsterdam, The Netherlands, 19.-25.4.2007, 2007, pp31Meeting Abstract
• S Endter, M Gumbleton, P Buckland, CM Lehr, C Ehrhardt, RT-PCR analysis of PEPT1, PEPT2, OCT2, OCTN2 and OATP in human lung epithelial cell cultures, 3rd Pharmaceutical World Sciences Congress, Amsterdam, The Netherlands, 19.-25.4.2007, 2007, pp50Meeting Abstract
• L Horálková, S Endter, P Dole al, C Ehrhardt, Characterisation of the rat alveolar type I-like epithelial cell line R3/1 as an in vitro absorption model, 3rd Pharmaceutical Sciences World Congress, Amsterdam, The Netherlands, 19.-25.04.2007, 2007, pp51Meeting Abstract
• E Passante, C Ehrhardt, H Sheridan, N Frankish, Effect of novel indanes on the degranulation of rat basophilic leukemia mast cells (RBL-2H3), FASEB J, Experimental Biology Meeting 2007, Washington, DC, 28.04.-02.05.2007, 21, (5), 2007, pp574.9Meeting Abstract
• E Passante, S Endter, MH Tindal, MR Pankratz, NH Frankish, C Ehrhardt, Albuterol is net absorbed across human bronchial epithelial cell layers in an enantiomer-dependent fashion, FASEB J, Experimental Biology Meeting 2007, Washington, DC, 28.04.-02.05.2007, 21, (5), 2007, pp881.2Meeting Abstract
• S Endter, E Passante, MH Tindal, MR Pankratz, NH Frankish, C Ehrhardt, Albuterol but not formoterol shows enantiomer-dependent net absorption across human bronchial epithelial cell layers, Am J Respir Crit Care Med , Annual Meeting of the American Thoracic Society 2007, San Franscisco, CA, 18.-23.05.2007, 175, 2007, ppA751Meeting Abstract
• C Ehrhardt, Monolayers of human alveolar epithelial cells as tools in biomedical research, California Pacific Medical Center Research Institute, San Francisco, CA, 18.05.2007, 2007Invited Talk
• C Ehrhardt, Human alveolar epithelial cells in primary culture as a tool for physiological studies, University College Cork, Department of Physiology, Cork, Ireland, 11.12.2006, 2006Invited Talk
• C Ehrhardt, Active drug transport in the lung, 11. Active drug transport in the lung. 04.10.2007, APS Inhalation and Biopharmaceutics Symposium - Biopharmaceutics of Inhaled Drug Delivery, London, UK, 04.10.2007, 2007Invited Talk
• E Passante, C Ehrhardt, H Sheridan, N Frankish, In vitro inhibition of rat basophilic leukaemia mast cell (RBL-2H3) degranulation by novel indane compounds. , Inflamm Res, 36th Annual Meeting of the European Histamine Release Society, Firenze, Italy, 09.-12.05.2007, 57, (S1), 2008, ppS01-S02Meeting Abstract
• S Endter, M Gumbleton, C Ehrhardt, Characterisation of ABC- and SLC-transporter mRNA transcripts in human respiratory epithelial cells, AAPS J, 2007 AAPS National Biotechnology Conference, San Diego, CA, 24.-27.06.2007, 9, (S1), 2007, ppT2072Meeting Abstract
• L Horálková, S Endter, P Dole al, C Ehrhardt, The rat alveolar type I-like epithelial cell line R3/1 as an in vitro model for pulmonary drug disposition, AAPS J, 2007 AAPS National Biotechnology Conference, San Diego, CA, 24.-27.06.2007, 9, (S1), 2007, ppT2073Meeting Abstract
• S Endter, M Gumbleton, C Ehrhardt, Expression of ABC- and SLC-transporter mRNA transcripts in human lung epithelial cells, AAPS J, 21st Annual Meeting of the AAPS, San Diego, CA, 11.-15.11.2007, 9, (S2), 2007, ppM2016Meeting Abstract
• L Horálková, S Endter, P Dole al, C Ehrhardt, Characterisation of the rat alveolar epithelial cell line R3/1 as an in vitro model for drug disposition studies, AAPS J, 21st Annual Meeting of the AAPS, San Diego, CA, 11.-15.11.2007, 9, (S2), 2007, ppM1216Meeting Abstract
• L Horálková, S Endter, R Koslowski, C Ehrhardt, Characterisation of the rat alveolar epithelial type I-like cell line R3/1 for use as an in vitro model of pulmonary drug disposition, Drug Delivery to the Lungs 18, Edinburgh, UK, 12.-14.12.2007, 2007, pp141-143Meeting Abstract
• S Endter, M Gumbleton, C Ehrhardt, Qualitative analysis of mRNA transcripts for ABC- SLC- and SLCO-transporter in human respiratory epithelial cells, Drug Delivery to the Lungs 18, Edinburgh, 12.-14.12.2007, 2007, pp200-201Meeting Abstract
• C Ehrhardt, 5th Thematic Network Meeting of the Galenos Marie Curie Early Research Training Programme of the 6th Framework, 08.-11.09.2007, 2007, Dublin, IrelandMeetings /Conferences Organised
• C Ehrhardt, Symposium on the Fluid Bed Coating of Micro Pellets, 26.-27.09.2007, 2007, Dublin, IrelandMeetings /Conferences Organised
• J O'Meara, L Visdal Johnsen, C Ehrhardt, J Coppins, N Frankish, H Kelleher, Y Li, F de Sousa Menezes, Bioactivity guided fractionation of Isodon yunnanensis Handel-Mazzetti, using A549 human alveolar epithelial lung cancer cell line, 50th Anniversary Meeting of the Phytochemical Society of Europe, Cambridge, UK, 11.-14.04.2007, 2007Meeting Abstract
• J O'Meara, J Coppins, C Ehrhardt, I Hook, N Frankish, H Sheridan, F de Sousa Menezes, Phytochemical and pharmacological evaluation of aqueous extracts of seven Plectranthus species. , 50th Anniversary Meeting of the Phytochemical Society of Europe, Cambridge, UK, 11.-14.04.2007, 2007Meeting Abstract
• J Coppins, I Hook, C Nestor, H Sheridan, C Ehrhardt, N Frankish, Inhibition of LFA-1 mediated T-Cell motility by Naphthoquinones, Royal Academy of Medicine in Ireland, Biomedical Sciences Section, Winter Meeting 2007, Dublin, Ireland , 11.01.2007 , 2007Meeting Abstract
• P Stasiak, C Ehrhardt, M Sznitowska, Biopharmaceutical evaluation of a conjugate of ibuprofen with 3-hydroxybutyric acid oligomers, 7th International Conference on Biological Barriers and Nanomedicine -Advanced Drug Delivery and Predictive non vivo Testing Technologies, Saarbrücken, Germany, 20-29/02/2008, 2008Meeting Abstract
• C Ehrhardt, M Gumbleton, S Endter, Analysis of mRNA for ABC - SLC- and SLCO-transporter in human respiratory epithelial cells, FASEB J, Experimental Biology Meeting 2009, San Diego, CA, 05-09/04/2008, 22, 2008, pp918.6Meeting Abstract
• C Ehrhardt, S Endter, R Andersen, R Koslowski, L Horálková, The R3/1 alveolar epithelial type I like cell line - Characterisation as an in vitro model for drug disposition, FASEB J, Experimental Biology Meeting 2009, San Diego, CA, 05-09/04/2008, 22, 2008, pp762.5Meeting Abstract
• MM Gaspar, C Ehrhardt, Influence of nebulization on physicochemical properties of liposomes., Respiratory Drug Delivery, Respiratory Drug Delivery 2008, Scottsdale, AZ, 11-15/05/2008, 11, (3), 2008, pp771-774Meeting Abstract
• L Horálková, S Endter, R Andersen, R Koslowski, C Ehrhardt, Characterization of the R3/1 cell line as a type I alveolar epithelial cell model for biopharmaceutical studies., Respiratory Drug Delivery, Respiratory Drug Delivery 2008, Scottsdale, AZ, 11-15/05/2008, 11, (3), 2008, pp775-778Meeting Abstract
• C Ehrhardt, Drug disposition in the lung - recent advantages in understanding the role of drug transporters, Respiratory Drug Delivery 2008, Scottsdale, AZ, 12/05/2008, 2008Invited Talk
• L Horálková, S Endter, R Koslowski, C Ehrhardt, The rat alveolar epithelial type I-like cell line R3/1 - Characterisation as an in vitro model for drug disposition, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2008, Toronto, Canada, 16-21/05/2008, 177, 2008, ppA197Meeting Abstract
• S Endter, M Gumbleton, C Ehrhardt, Expression analysis of ABC - SLC- and SLCO-transporter mRNA in human respiratory epithelial cells, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2008, Toronto, Canada, 16-21/05/2008, 177, 2008, ppA204Meeting Abstract
• E Passante, C Ehrhardt, H Sheridan, N Frankish, Toll-like receptors and RBL-2H3 mast cells, Inflamm Res, 37th Annual Meeting of the European Histamine Release Society, Stockholm, Sweden, 07-10/05/2008, 58, (S1), 2009, pp11-12Meeting Abstract
• P Stasiak, C Ehrhardt, M Sznitowska, Ibuprofen 3-hydroxybutyric acid oligomer conjugates - physicochemical characterisation and cytotoxicity studies, 19th International Symposium on Pharmaceutical and Biomedical Analysis, Gdańsk, Poland, 08-12/6/2008, 2008, pp150Meeting Abstract
• L Horálková, S Endter, R Andersen, R Koslowski, C Ehrhardt, R3/1 alveolar epithelial cells - characterisation of a new in vitro model for pulmonary drug disposition, 2nd International Symposium "Cellular Delivery of Therapeutic Macromolecules 2008", Cardiff, UK, 22-25/6/2008, 2008, pp77Meeting Abstract
• P Stasiak, M Sznitowska, C Ehrhardt, Caco-2 cell monolayer studies of ibuprofen - oligo (3-hydroxybutyric acid) conjugates, 2nd International Symposium "Cellular Delivery of Therapeutic Macromolecules 2008", Cardiff, UK, 22-25/6/2008, 2008, pp82Meeting Abstract
• L Baginski, C Ehrhardt, Investigation of mRNA expression of proteolytic enzymes in Calu-3 bronchial epithelial cells, 2nd International Symposium "Cellular Delivery of Therapeutic Macromolecules 2008", Cardiff, UK, 22-25/6/2008, 2008, pp78Meeting Abstract
• S Endter, M Gumbleton, C Ehrhardt, Charaterisation of organic cation transporters in human respiratory epithelial cells, 2nd International Symposium "Cellular Delivery of Therapeutic Macromolecules 2008", Cardiff, UK, 22-25/6/2008, 2008, pp80Meeting Abstract
• MM Gaspar, F de Sousa Menezes, MW Radomski, C Ehrhardt, Effects of liposomal surface charge on human platelet aggregation, Proc Intern Symp Control Rel Bioact Mat, 35th Annual Meeting of the Controlled Release Society, New York, NY, 12-16/07/2008, 35, (1), 2008, pp748Meeting Abstract
• MM Gaspar, C Ehrhardt, Physicochemical characterisation of liposomes for aerosol delivery, Proc Intern Symp Control Rel Bioact Mat, 35th Annual Meeting of the Controlled Release Society, New York, NY, 12-16/07/2008, 35, (1), 2008, pp774Meeting Abstract
• P Stasiak, S Endter, C Ehrhardt, M Sznitowska, In Vitro studies of a novel ibuprofen 3-hydroxybutyric acid conjugate, Proc Intern Symp Control Rel Bioact Mat , 35th Annual Meeting of the Controlled Release Society, New York, NY, 12-16/07/2008, 35, (1), 2008, pp786Meeting Abstract
• C Ehrhardt, Liposome aerosols in (lung)cancer therapy, 4th International Intensive Course and Workshop on Nanomedicines - Nanoparticulates for Drug Delivery, Patras, Greece, 16/09/2008, 2008Invited Talk
• C Ehrhardt, The role of RAGE in epithelial-mesenchymal transition in the human alveolus, 28th West Coast Salt and Water Club Meeting, Morro Bay, CA, 14/03/2009, 2009Invited Talk
• C Ehrhardt, G Tachon, S Endter, Organic cation transporter expression and function in human pulmonary epithelial cells, FASEB J, Experimental Biology Meeting 2009, New Orleans, LA, 18-22/04/2009, 23, 2009, pp748.6Meeting Abstract
• MM Gaspar, A Radomska, O Gobbo, MW Radomski, C Ehrhardt, Effect of inhaled anti-cancer liposomes in an orthotopic lung cancer model in the nude rat, J Aerosol Med Pulm Drug Deliv, 17th Congress of the International Society for Aerosols in Medicine, Monerey, CA, 10-14/05/2009, 22, (2), 2009, pp190Meeting Abstract
• L Baginski, GC Boutsikaris, G Tachon, C Ehrhardt, Peptidases expression patterns in respiratory epithelial cells, J Aerosol Med Pulm Drug Deliv, 17th Congress of the International Society for Aerosols in Medicine, Monterey, CA, 10-14/05/2009, 22, (2), 2009, pp195Meeting Abstract
• C Ehrhardt, S Endter, G Tachon, M Gumbleton, Expression and activity of organic cation transporter in human respiratory epithelial cells, J Aerosol Med Pulm Drug Deliv, 17th Congress of the International Society for Aerosols in Medicine, Monterey, CA, 10-14/05/2009, 22, (2), 2009, pp198Meeting Abstract
• C Ehrhardt, S Endter, G Tachon, M Gumbleton, Organic cation transporter expression and activity in human respiratory epithelial cells, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2009, San Diego, CA, 15-20/05/2009, 179, (1), 2009, ppA4939Meeting Abstract
• L Baginski, G Tachon, C Ehrhardt, Investigations on peptidases expression pattern in respiratory epithelial cells, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2009, San Diego, CA, 15-20/05/2009, 179, (1), 2009, ppA4969Meeting Abstract
• L Baginski, GC Boutsikaris, C Ehrhardt, The role of epithelial proteases in the pulmonary absorption of calcitonin, AAPS J, 23rd Annual Meeting of the AAPS, Los Angeles, CA, 08-12/11/2009, 11, (S2), 2009, ppT3103Meeting Abstract
• JJ Salomon, S Endter, C Ehrhardt, Organic cation transporters are functionally expressed in human respiratory epithelial cells, AAPS J, 23rd Annual Meeting of the AAPS, Los Angeles, CA, 08-12/11/2009, 11, (S2), 2009, ppW5134Meeting Abstract
• J Swaminathan, MM Gaspar, C Ehrhardt, Characterisation of liposome aerosols generated with new generation nebulisers, AAPS J, 23rd Annual Meeting of the AAPS, Los Angeles, CA, 08-12/11/2009, 11, (S2), 2009, ppR6396Meeting Abstract
• P Stasiak, M Sznitowska, C Ehrhardt, Ibuprofen-3-hydroxybutyric acid oligomer conjugates for drug delivery applications, AAPS J, 22nd Annual Meeting of the AAPS, Atlanta, GA, 16-20/11/2008, 10, (S2), 2008, ppM1168Meeting Abstract
• M Gaspar, U Bakowsky, C Ehrhardt, Aerosolised liposomes: influence of physicochemical properties and nebulisation device, AAPS J, 22nd Annual Meeting of the AAPS, Atlanta, GA, 16-20/11/2008, 10, (S2), 2008, ppT2163Meeting Abstract
• L Baginski, C Ehrhardt, Comparison of peptidases expression in Calu-3 and Caco-2 cells by RT-PCR, AAPS J, 22nd Annual Meeting of the AAPS, Atlanta, GA, 16-20/11/2008, 10, (S2), 2008, ppW5272Meeting Abstract
• C Ehrhardt, The use of in vitro epithelial cell culture models for pulmonary delivery, 1st SFI Irish Drug Delivery Research Network (IDDRN) Cluster Conference - Optimising Drug Delivery, Dublin, 19/08/2009, 2009Invited Talk
• C Ehrhardt, Absorption mechanisms for biopharmaceuticals across respiratory epithelium, 1000 Years of Pharmaceutical Aerosols, Reykjavik, Iceland, 02/10/2009, 2009Invited Talk
• C Ehrhardt, Development of liposome aerosols for (lung)cancer therapy by inhalation, University of Southern California, School of Pharmacy, Los Angeles, CA, 27/03/2009, 2009Invited Talk
• J Swaminathan, MM Gaspar, C Ehrhardt, Characterisation of liposome aerosols generated with the AeroProbe nebulisation catheter, DDL Proceedings, Drug Delivery to the Lungs 20, Edinburgh, UK, 09-11/12/2009, 2009, pp76-79Meeting Abstract
• C Ehrhardt, Expression of drug transporter proteins in human respiratory epithelial barrier, University of Toyama. Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan, 28/01/2010 , 2010Invited Talk
• C Ehrhardt, Surface modified liposomes for targeted aerosol delivery to lung tumours, 8th International Conference and Workshop on Biological Barriers - In Vitro Tools, Nanotoxicology and Nanomedicine, Saarbrücken, Germany, 22/03/2010, 2010Invited Talk
• E Schwagerus, ST Buckley, C Ehrhardt, Functional expression of the epithelial sodium channel delta subunit in human respiratory epithelial cells, FASEB J, Experimental Biology Meeting 2010, Anaheim, CA, 24-28/04/2010, 24, 2010, pp611.14Meeting Abstract
• JJ Salomon, C Ehrhardt, Nanoparticles attenuate P-glycoprotein function in A549 cells, FASEB J, Experimental Biology Meeting 2010, Anaheim, CA, 24-28/04/2010, 24, 2010, pp758.1Meeting Abstract
• L Baginski, U Bakowsky, C Ehrhardt, Stability of inhaled salmon calcitonin at the respiratory epithelial barrier, Am J Respir Crit Care Med , Annual Meeting of the American Thoracic Society 2010, New Orleans, LA, 14-19/05/2010, 181, (1), 2010, pp3622Meeting Abstract
• E Schwagerus, ST Buckley, C Ehrhardt, ENaC delta-subunit is functionally expressed in human respiratory epithelial cells, Am J Respir Crit Care Med , Annual Meeting of the American Thoracic Society 2010,, New Orleans, LA, 14-19/05/2010, 181, (1), 2010, ppA6454Meeting Abstract
• L Baginski, ST Buckley, U Bakowsky, C Ehrhardt, Stability of salmon calcitonin against trypsin, chymotrypsin and neutrophil elastase in human lung epithelial cells, Sci Pharm, 8th Central European Symposium on Pharmaceutical Technology, Graz, Austria, 16-18/09/2010, 78, (3), 2010, pp720Meeting Abstract, URL , TARA - Full Text
• C Ehrhardt, Drug disposition in the lung - how in vitro models can help optimising inhalation therapy, Universität Basel, Departement Pharmazeutische Wissenschaften, Basel, Switzerland, 16/08/2010, 2010Invited Talk
• C Ehrhardt, Pulmonary drug delivery and inhalation biopharmaceutics, Advanced Delivery Strategies for Pharmaceutics and Cosmetics, Lyon, France, 07/10/2010, 2010Invited Talk
• C Ehrhardt, Culturing alveolar type II epithelial cells from human tissue specimens, BRU/GSK Epithelial Cells in Idiopathic Pulmonary Fibrosis Workshop, Nottingham, UK, 15/10/2010, 2010Invited Talk
• JJ Salomon, C Ehrhardt, A functional and toxicological evaluation of latex nanoparticles: Effect on P-glycoprotein function in A549 cells, AAPS J, 24th Annual Meeting of the AAPS, New Orleans, LA, 14-18/11/2010, 12, (S2), 2010, ppM1216Meeting Abstract
• L Baginski, ST Buckley, U Bakowsky, C Ehrhardt, Stability of inhaled salmon calcitonin against trypsin, chymotrypsin and neutrophil elastase, AAPS J, 24th Annual Meeting of the AAPS, New Orleans, LA, 14-18/11/2010, 12, (S2), 2010, ppW2026Meeting Abstract
• J Swaminathan, C Ehrhardt, Salmon calcitonin delivery via the lung using liposomal carriers, AAPS J, 24th Annual Meeting of the AAPS, New Orleans, New Orleans, LA, 24th Annual Meeting , 12, (S2), 2010, ppW2029Meeting Abstract
• ST Buckley, V Patel, MS Krishnaveni, ED Crandall, C Ehrhardt, Z Borok, Troglitazone attenuates TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells, AAPS J, 24th Annual Meeting of the AAPS, New Orleans, 14-18/11/2010, 12, (S2), 2010, ppW4438Meeting Abstract
• J Swaminathan, C Ehrhardt, Formulation and in-vitro characterisation of liposomal systems for salmon calcitonin (sCT) delivery to the lung, Drug Delivery to the Lungs 21, Edinburgh, Scotland, UK, 08-10/12/2010, 2010, pp327-330Meeting Abstract
• JJ Salomon, M Tachikawa, KI Hosoya, C Ehrhardt, Beta-agonists interfere with the transport of organic cations across the human alveolar epithelial barrier, AAPS Workshop on Drug Transporters in ADME: From the Bench to the Bedside, Bethesda, MD, 14-16/03/2011, 2011, ppW3018Meeting Abstract
• JJ Salomon, S Endter, ST Buckley, C Ehrhardt, Translocation pathways of 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide (ASP+) across human respiratory epithelial cell monolayers, AAPS Workshop on Drug Transporters in ADME: From the Bench to the Bedside, Bethesda, MD, 14-16/03/2011, 2011, ppW3019Meeting Abstract
• S Etzbach, JJ Salomon, F Májer, MN Mohd Najib, CM Lehr, JF Gilmer, C Ehrhardt, Fluorescence-labelled bile acids as novel tools to measure organic anionic transporting polypeptide (OATP) function, AAPS Workshop on Drug Transporters in ADME: From the Bench to the Bedside, Bethesda, MD, 14-16/03/2011, 2011, ppW3020Meeting Abstract
• E Schwagerus, ST Buckley, C Ehrhardt, Studies on the activity of the delta-ENaC in human respiratory epithelial cell lines, FASB J, Experimental Biology Meeting 2011, Washington, DC, 09-13/04/2011, 25, 2011, pp659.1Meeting Abstract
• JJ Salomon, T Yahara, KI Hosoya, C Ehrhardt, Activity assessment of organic cation/carnitine transporters in A549 alveolar epithelial cells, FASEB J, Experimental Biology Meeting 2011, Washington, DC, 09-13/04/2011, 25, 2011, pp1015.1Meeting Abstract
• JJ Salomon, KI Hosoya, C Ehrhardt, Competitive inhibition of [14C]-TEA uptake in A549 cell monolayers by formoterol and salbutamol, FASEB J, Experimental Biology Meeting 2011, Washington, DC, 09-13/04/2011, 25, 2011, pp1015.2Meeting Abstract
• L DeMaio, ST Buckley, P Flodby, A Banfalvi, MS Krishnaveni, Y Xing, C Ehrhardt, P Minoo, ED Crandall, Z Borok, Induction of epithelial-mesenchymal transition (EMT) in alveolar epithelial cells (AEC) by type I collagen (Col1) involves signaling via transforming growth factor-β type I receptor (TβRI), Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2011, Denver, CO, 13-18/05/2011, 183, 2011, ppA2709Meeting Abstract
• V Patel, ST Buckley, MS Krishnaveni, M Ivan, L DeMaio, ED Crandall, C Ehrhardt, Z Borok, Troglitazone attenuates TGF-β1-induced epithelial-mesenchymal transition (EMT) in alveolar epithelial cells (AEC) through peroxisome proliferator activated receptor γ (PPARγ) receptor-independent mechanisms, Am J Respir Crit Care Med , Annual Meeting of the American Thoracic Society 2011, Denver, CO, 13-18/05/2011, 183, 2011, ppA3508Meeting Abstract
• JJ Salomon, T Yahara, KI Hosoya, C Ehrhardt, Characterisation of organic cation/carnitine transporters in human alveolar epithelial cell monolayers (A549), Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2011, Denver, CO, 13-18/05/2011, 183, 2011, ppA4237Meeting Abstract
• JJ Salomon, KI Hosoya, C Ehrhardt, Formoterol and salbutamol are competitive inhibitors of [14C]-TEA uptake in A549 cell monolayers, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2011, Denver, CO, 13-18/05/2011, 183, 2011, ppA4238Meeting Abstract
• E Schwagerus, ST Buckley, C Ehrhardt, Expression and function of the epithelial sodium channel delta subunit in human respiratory, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2011, Denver, CO, 13-18/05/2011, 183, 2011, ppA4229Meeting Abstract
• C Ehrhardt, Nanoparticles in pulmonary drug delivery: Applications in lung cancer & gene delivery, 18th Congress of International Society for Aerosols in Medicine, Rotterdam, NL, 20/06/2011, 2011Invited Talk
• C Ehrhardt, Atomic force microscopy (AFM) and high content analysis (HCA) as novel tools to quantify alveolar EMT, 30th West Coast Salt and Water Club Meeting, Morro Bay, CA, 12/03/2011, 2011Invited Talk
• C Ehrhardt, Do drug transporters in the lung have an impact on respiratory drug disposition? , Medical University of Vienna, Department of Pathophysiology, Vienna, Austria, 30/09/2011, 2011Invited Talk
• C Ehrhardt, Understanding absorption across the pulmonary mucosa, Informa's Inhalation Drug Development, London, UK, 13/10/2011, 2011Invited Talk
• F Tewes, L Tajber, C Ehrhardt, AM Healy, Formulation of colistin-ambroxol microparticles for passive targeting of lung infections, AAPS J, 25th Annual Meeting of the AAPS, Washington, DC, 23-27/11/2011, 13, (S2), 2011, ppM1046Meeting Abstract
• J Swaminathan, C Ehrhardt, Salmon calcitonin delivery via the lung using liposomal carriers, AAPS J, 25th Annual Meeting of the AAPS, Washington, DC, 23-27/10/2011, 13, (S2), 2011, ppT2068Meeting Abstract
• F Tewes, M Zurek, C Ehrhardt, Y Crémillieux, OL Gobbo, Manganese: A new contrast agent for lung imaging?, AAPS J, 25th Annual Meeting of the AAPS, Washington, DC, 23-27/10/2011, 13, (S2), 2011, ppT2069Meeting Abstract
• JJ Salomon, S Etzbach, F Májer, JF Gilmer, CM Lehr, C Ehrhardt, Fluorescent bile acids for the assessment of organic anionic transporting polypeptide (OATP) function, AAPS J, 25th Annual Meeting of the AAPS, Washington, DC, 23-27/10/2011, 13, (S2), 2011, ppT2119Meeting Abstract
• JJ Salomon, KI Hosoya, C Ehrhardt, Involvement of organic cation transporters (OCTs) in β2-agonist uptake at the human respiratory epithelial barrier, AAPS J, 25th Annual Meeting of the AAPS, Washington, DC, 23-27/10/2011, 13, (S2), 2011, ppT2120Meeting Abstract
• JJ Salomon, S Endter, ST Buckley, C Ehrhardt, Uptake pathways for 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide (ASP+) in human respiratory epithelial cell monolayers, AAPS J, 25th Annual Meeting of the AAPS, Washington, DC, 23-27/10/2011, 13, (S2), 2011, ppT2121Meeting Abstract
• JJ Salomon, KI Hosoya, C Ehrhardt, Impact of β2-agonists on transcellular pathways of organic cations at the human alveolar epithelial barrier, 26th Annual Meeting of the Japanese Society for the Study of Xenobiotics, Hiroshima, Japan, 16-18/11/2011, 2011, pp220Meeting Abstract
• JJ Salomon, KI Hosoya, C Ehrhardt, Expression of membrane transport proteins in the lung, 26th Annual Meeting of the Japanese Society for the Study of Xenobiotics, Hiroshima, Japan, 16-18/11/2011, 2011, pp244Meeting Abstract
• C Ehrhardt, Expression of membrane transport proteins in the lung, 26th Annual Meeting of the Japanese Society for the Study of Xenobiotics, Hiroshima, Japan, 16/11/2011, 2011Invited Talk
• JJ Salomon, KI Hosoya, C Ehrhardt, Drug transporters in the respiratory mucosa: expression and interplay with β-receptor agonists, Drug Delivery to the Lungs 22, Edinburgh, Scotland, UK, 07-09/12/2011, 2011, pp61-64Meeting Abstract
• C Ehrhardt, Interactions between organic cation transporters and inhaled medicines, 31st West Coast Salt and Water Club Meeting, Cambria, CA, 10/03/2012, 2012Invited Talk
• C Ehrhardt, Delta-ENaC expression and function in the airways, 31st West Coast Salt and Water Club Meeting, Cambria, CA, 10/03/2012, 2012Invited Talk
• JJ Salomon, C Ehrhardt, Transport of organic cations across human bronchial and bronchiolar epithelial barriers in vitro, FASEB J, Experimental Biology Meeting 2012, San Diego, CA, 21-25/04/2012, 26, 2012, pp694.9Meeting Abstract
• E Schwagerus, B Illek, H Fischer, C Ehrhardt, Studies on the functional expression of epithelial sodium channel delta subunit (δ-ENaC) in human respiratory epithelial cells in vitro, FASEB J, Experimental Biology Meeting 2012, San Diego, CA, 21-25/04/2012, 26, 2012, pp696.1Meeting Abstract
• C Ehrhardt, Regional distribution of organic cation transporters in human lung epithelial cells: Possible implications for aerosol therapy, Respiratory Drug Delivery 2012, Phoenix, AZ, 14/05/2012, 2012Invited Talk
• E Schwagerus, B Illek, H Fischer, C Ehrhardt, Functional expression of epithelial sodium channel delta subunit in human respiratory epithelial cells in vitro, Am J Respir Crit Care Med , Annual Meeting of the American Thoracic Society 2012, San Francisco, CA, 18-23/05/2012, 185, 2012, ppA3528Meeting Abstract
• JJ Salomon, C Ehrhardt, Understanding the pathways of organic cation transport at the respiratory epithelial barrier, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2012, San Francisco, CA, 18-23/05/2012, 185, 2012, ppA3529Meeting Abstract
• C Ehrhardt, Drug transporters in the lung - are they relevant for pulmonary drug disposition? , Pharmazentrum der Universität Wien, Austria, 31/05/2012, 2012Invited Talk
• C Ehrhardt, Drug Transporters in the Lung - Fact or Fiction? , 2012 Drug Delivery Symposium honouring Prof. Vincent H. L. Lee, Aurora, CO, 14/06/2012, 2012Invited Talk
• JJ Salomon, C Ehrhardt, Functional expression of organic cation/carnitine transporters (OCT/Ns) in lung epithelial barrier in vitro, AAPS J, 26th Annual Meeting of the AAPS, Chicago, IL, 14-18/10/2012, 14, (S2), 2012, ppM1063Meeting Abstract
• JJ Salomon, Y Hagos, C Ehrhardt, Interaction of β2-receptor agonists with organic cation transporters in respiratory epithelia, AAPS J, 26th Annual Meeting of the AAPS, Chicago, IL, 14-18/10/2012, 14, (S2), 2012, ppM1064Meeting Abstract
• JJ Salomon, JC Gausterer, E Schwagerus, F Gabor, C Ehrhardt, H441 - A useful in vitro model for biopharmaceutical studies of alveolar epithelial barrier, AAPS J, 26th Annual Meeting of the AAPS, Chicago, IL, 14-18/10/2012, 14, (S2), 2012, ppM1065Meeting Abstract
• JJ Salomon, P Galeron, N Schulte, PR Morow, D Severynse-Stevens, AJ Hickey, C Ehrhardt, In vitro permeability studies of a novel inhaled antibiotic (CPZEN-45) for the treatment of tuberculosis, AAPS J, 26th Annual Meeting of the AAPS, Chicago, IL, 14-18/10/2012, 14, (S2), 2012, ppT2024Meeting Abstract
• C Ehrhardt, Drug transporter research in the lungs - Past, present and future, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan, 19/11/2012, 2012Invited Talk
• JJ Salomon, JC Gausterer, E Schwagerus, F Gabor, C Ehrhardt, Characterisation of an in vitro model for biopharmaceutical studies of distal lung epithelial barrier: NCI-H441, 27th Annual Meeting of the Japanese Society for the Study of Xenobiotics, Chiba, Japan, 20-22/11/2012, 2012, pp220Meeting Abstract
• JJ Salomon, Y Hagos, C Ehrhardt, Beta-2-receptor agonists are inhibitors but not substrates of putative organic cation transporters, 27th Annual Meeting of the Japanese Society for the Study of Xenobiotics, Chiba, Japan, 20-22/11/2012, 2012, pp221Meeting Abstract
• C Ehrhardt, Characterisation of an in vitro model for biopharmaceutical studies of distal lung epithelial barrier: NCI-H441, 27th Annual Meeting of the Japanese Society for the Study of Xenobiotics, Chiba, Japan, 20-22/11/2012, 2012Oral Presentation
• C Ehrhardt, Beta-2-receptor agonists are inhibitors but not substrates of putative organic cation transporters, 27th Annual Meeting of the Japanese Society for the Study of Xenobiotics, Chiba, Japan, 20-22/11/2012, 2012Oral Presentation
• C Ehrhardt, Drug transporters in the lung - expression and role in pulmonary drug disposition, Ph.D. Course on Biological Membranes, Drug Targets and Absorption Barriers, Copenhagen, Denmark, 23/11/2012, 2012Invited Talk
• JJ Salomon, Y Hagos, C Ehrhardt, Beta-2 agonists are specific inhibitors but not substrates of organic cation transporters in the lung, Drug Delivery to the Lungs 23, Edinburgh, Scotland, UK, 05-07/12/2012, 2012, pp322-325Meeting Abstract
• N Chadderton, A Palfi, S Millington-Ward, O Gobbo, N Overlack, M Carrigan, M O'Reilly, M Campbell, C Ehrhardt, U Wolfrum, P Humphries, PF Kenna, GJ Farrar, Intravitreal delivery of AAV-NDI1 for the treatment of Leber Hereditary Optic Neuropathy, Hum Gene Ther, Retina 2011 - Fighting Blindness, Dublin, Ireland, 11-12/11/2011, 23, (10), 2012, ppA55-A56Meeting Abstract
• C Ehrhardt, Y Hagos, JJ Salomon, Organic cation transporters in the lung are inhibited by β2-agonists, AAPS Workshop on Drug Transporters in ADME: From the Bench to the Bedside, Bethesda, MD, 17-20/03/2012, 2013, ppM1004Meeting Abstract
• C Ehrhardt, JJ Salomon, Human lung epithelial cells functionally express organic cation/carnitine transporters (OCT/Ns) in vitro, AAPS Workshop on Drug Transporters in ADME: From the Bench to the Bedside, Bethesda, MD, 17-20/03/2012, 2013, ppM1005Meeting Abstract
• C Ehrhardt, Drug transport across the epithelial barrier: Is it all just diffusion?, 19th Congress of International Society for Aerosols in Medicine, Chapel Hill, NC, 09/04/2013, 2013Invited Talk
• JJ Salomon, Y Hagos, C Ehrhardt, Beta-2-receptor agonists inhibit but are not transported by organic cation transporters, J Aerosol Med Pulm Drug Deliv , 19th Congress of International Society for Aerosols in Medicine, Chapel Hill, NC, 06-10/04/2013, 26, (2), 2013, ppA40Meeting Abstract
• JJ Salomon, JC Gausterer, E Schwagerus, C Ehrhardt, Characterisation of NCI-H441 cells as an in vitro model of human distal lung epithelium, J Aerosol Med Pulm Drug Deliv, 19th Congress of International Society for Aerosols in Medicine, Chapel Hill, NC, 06-10/04/2013, 26, (2), 2013, ppA40Meeting Abstract
• C Ehrhardt, Drug transport across the epithelial barrier: Is it all just diffusion?, J Aerosol Med Pulm Drug Deliv, 19th Congress of International Society for Aerosols in Medicine, Chapel Hill, NC, 06-10/04/2013, 26, (2), 2013, ppA10Meeting Abstract
• C Ehrhardt, JC Gausterer, E Schwagerus, JJ Salomon, Characterisation of H441 cells as an in vitro model of distal lung epithelial barrier, FASEB J, Experimental Biology Meeting 2013, Boston, MA, 20-24/04/2014, 27, 2013, pp722.1Meeting Abstract
• C Ehrhardt, Y Hagos, JJ Salomon, Beta-2 agonists are inhibitors but not substrates of organic cation transporters, Am J Respir Crit Care Med, Annual Meeting of the American Thoracic Society 2013, Philadelphia, PA, 17-22/05/2013, 187, 2013, ppA1890Meeting Abstract
• C Ehrhardt, In vitro models of human respiratory epithelial barriers and their application in biopharmaceutical studies, Chiesi Pharmaceutici, Parma, Italy, 19/06/2013, 2013Invited Talk
• C Ehrhardt, Drug Transporters in the Lung - Advances and Challenges, School of Pharmacy, Chinese University of Hong Kong, Hong Kong, China, 25/06/2013, 2013Invited Talk
• C Ehrhardt, Characterisation of HCI-H441 cells as an in vitro model of small airways epithelial barrier, Inhalation Asia 2013, Hong Kong, China, 26-28/06/2013, 2013Invited Talk
• JJ Salomon, Y Hagos, C Ehrhardt, Beta-2 receptor agonists are selective inhibitors of organic cation transporter 1 in respiratory epithelial cells, Inhalation Asia 2013, Hong Kong, China, 26-28/06/2013, 2013, pp42Meeting Abstract
• JJ Salomon, JC Gausterer, E Schwagerus, C Ehrhardt, Characterisation of HCI-H441 cells as an in vitro model of small airways epithelial barrier, Inhalation Asia 2013, Hong Kong, China, 26-28/06/2013, 2013, pp33Meeting Abstract
• C Ehrhardt, 2nd Galenus Workshop on Pulmonary Drug Delivery, 18-20/09/2013, 2013, Trinity College DublinMeetings /Conferences Organised
• C Ehrhardt, Anatomy and cell physiology of the respiratory tract, 2nd Galenus Workshop on Pulmonary Drug Delivery, Trinity College Dublin, 18-20/09/2013, 2013Invited Talk
• C Ehrhardt, Transporter proteins in the lung epithelium, 2nd Galenus Workshop on Pulmonary Drug Delivery, Trinity College Dublin, 18-20/09/2013, 2013Invited Talk
• C Ehrhardt, Do drug transporter proteins in the lung interfere with pulmonary drug disposition? , Department of Pharmaceutics and Therapeutics, Graduate School of Biomedical & Health Sciences, Hiroshima University, Japan, 07/10/2013, 2013Invited Talk
• C Ehrhardt, VE Muchitsch, F Gabor, JJ Salomon, Human bronchiolar epithelial cells functionally express P-glycoprotein and multidrug resistance-related protein-1, 28th Annual Meeting of the Japanese Society for the Study of Xenobiotics, Tokyo, Japan, 09-11/10/2013, 2013, pp2-B-O9-3Meeting Abstract
• C Ehrhardt, Human bronchiolar epithelial cells functionally express P-glycoprotein and multidrug resistance-related protein-1, 28th Annual Meeting of the Japanese Society for the Study of Xenobiotics, Tokyo, Japan, 09-11/10/2013, 2013Oral Presentation
• C Ehrhardt, MRP1 is functionally expressed in human distal lung epithelial cells, Göttinger Transportertage, Göttingen, Germany, 24/11/2013, 2013Invited Talk
• C Ehrhardt, Do drug transporters influence the disposition of inhaled drugs?, Drug Delivery to the Lungs 24, Edinburgh, Scotland, UK, 12/12/2013, 2013Invited Talk
• C Ehrhardt, A probable association between the ergothioneine transporter, OCTN1 and COPD, 33rd West Coast Salt and Water Club Meeting, Avila Beach, CA, 08/03/2014, 2014Invited Talk
• C Ehrhardt, 33rd West Coast Salt and Water Club Meeting, 07-08/03/2014, 2014, Avila Beach, CAMeetings /Conferences Organised
• C Ehrhardt, In vitro models of human distal lung and their application in pulmonary drug disposition research, Graduate School of Health, University of Technology, Sydney, Sydney, NSW, Australia, 09/04/2014, 2014Invited Talk
• C Ehrhardt, Drug Transport(ers) in the Lung: Challenges in Drug Development, Woolcock Institute of Medical Research, Sydney, NSW, Australia, 11/09/2014, 2014Invited Talk
• R Yumoto, N Sugimoto, Y Sasaki, C Yamamoto, J Nagai, C Ehrhardt, M Takano, Expression and function of a peptide transporter PEPT2 in alveolar epithelial cells in culture, 5th FIP Pharmaceutical Sciences World Congress, Melbourne, VIC, Australia, 13-16/04/2014, 2014Meeting Abstract
• VE Muchitsch, JC Gausterer, JJ Salomon, C Ehrhardt, Human bronchiolar epithelial cells functionally express P-glycoprotein and multidrug resistance-related protein-1, FASEB J, Experimental Biology Meeting 2014, San Diego, CA, 26-30/04/2014, 28, 2014, pp1064.11Meeting Abstract
• C Ehrhardt, Anatomy and cell physiology of the human lungs, ISPE Turkey Affiliate Pulmonary Drug Delivery Workshop, Istanbul, Turkey, 09/05/2014, 2014Invited Talk
• C Ehrhardt, Biopharmazie der Lunge - Spielen Arzneistofftransporter eine Rolle?, Institut für Pharmazeutische Technologie, Goethe-Universität, Frankfurt am Main, Germany, 04/06/2014, 2014Invited Talk
• C Ehrhardt, Drug disposition in the lung - what we do know and what we don't, Department of Physiology & Developmental Biology, Brigham Young University, Provo, UT, 15/05/2014, 2014Invited Talk
• C Ehrhardt, Spielen Arzneistofftransporter im Lungenepithel eine biopharmazeutische Rolle?, Institut für Pharmazeutische Technologie, Technische Universität Braunschweig, Braunschweig, Germany, 18/06/2014, 2014Invited Talk
• C Ehrhardt, The many unknowns of pulmonary drug disposition, Institut für Pharmazie, Freie Universität Berlin, Berlin, Germany, 18/07/2014, 2014Invited Talk
• C Ehrhardt, Transporter-Effekte bei der Arzneistoffabsorption in der Lunge, Abteilung Pharmazeutische Technologie, Ruprecht-Karls-Universität, Heidelberg, Germany, 22/07/2014, 2014Invited Talk
• C Ehrhardt, Wo geht's lang? Wege der Arzneistoffabsorption in der Lunge, Institut für Pharmazeutische Technologie und Biopharmazie, Philipps-Universität, Marburg, Germany, 02/09/2014, 2014Invited Talk
• C Ehrhardt, The Physiology and Pharmacology of Drug Transporters in the Lung, Institute of Physiological Chemistry, Medical Faculty Carl Gustav Carus, TU Dresden, Germany, 25/09/2014, 2014Invited Talk
• C Ehrhardt, In vitro, ex vivo and in vivo models of pulmonary drug disposition, SF Nano Workshop on Tools and Models for Translation of Advanced Drug Delivery Systems, Porto, Portugal, 03/10/2014, 2014Invited Talk
• C Ehrhardt, SH Park, JJ Salomon, S Micallef, Tobacco smoke-induced oxidative stress response is attenuated by OCTN1-mediated ergothioneine uptake in vitro, Drug Metab Rev, 19th North American ISSX/29th JSSX Meeting, San Francisco, CA, 19-23/10/2014, 47, (Suppl 1), 2015, pp297Meeting Abstract
• S Micallef, SH Park, JJ. Salomon, C Ehrhardt, Tobacco smoke-induced oxidative stress response in respiratory epithelial cells is attenuated by OCTN1-mediated ergothioneine uptake, AAPS J, 28th Annual Meeting of the AAPS, San Diego, CA, 02-06/11/2014, 16, (2), 2014, ppR6331Meeting Abstract

I have established an international reputation in the field of Pulmonary Biopharmaceutics. The scientific aim of my work is to describe the behaviour of drugs following their administration to the lung as inhaled aerosols, i.e. lung drug disposition and pulmonary epithelial transport. Moreover, I have developed a keen interest in the molecular origins of lung disease. Over the last 20 years, the incidence of lung-related diseases and the morbidity due to these conditions is increasing at more than 5% per year. With 1 in 7 people in Ireland having an undiagnosed lung condition and Ireland having the third highest death rate from lung disease in Europe, causing 1 in 5 deaths, the potential impact of my work becomes clear. In my lab we primarily employ pre-clinical models. We have established organotypic in vitro, ex vivo and experimental in vivo models, which allow a wide array of discovery and development studies. Inter alia, we have been credited with pioneering the development of primary cultures of human alveolar epithelial cells. The expertise of my laboratory includes techniques from the areas of pharmaceutics, pharmacokinetics, pharmacology, electrophysiology, cell and molecular biology and immunocytochemistry. The unique combination of cell physiological basis and pharmaceutical application has led to numerous research collaborations, nationally and internationally, as well as to a continuous stream of visiting researchers to my laboratory. At the moment, we are involved in a number of international, multidisciplinary, translational studies into the role that drug transporters play in the pathogenesis of lung diseases. In this context, we are studying, e.g. the role of ergothioneine and its physiological transporter OCTN1 in the development and progression of tobacco-related chronic obstructive pulmonary disease (COPD). This study brings together researcher from TCD, St. James's Hospital, Brigham Young University, University of Kanazawa and University Medical Center Groningen and is financially supported by a Clinical Investigator Award from the Flight Attendant Medical Research Institute (FAMRI). My lab continuously publishes in in high ranking peer-reviewed journals in the subject areas of Pharmaceutics, Pharmacology and Physiology. One of the highlights of our endeavours so far was the invitation to publish a review article in Nature Chemistry (Zelikin et al. 2016). Another of our publications (Paszko et al. 2011) achieved highly cited paper status according to Essential Science Indicators, i.e. it has received enough citations to place it in the top 1% of its academic field based on a highly cited threshold for the field and publication year. Chapters from Drug Absorption Studies, a book edited by me and published by Springer in 2008, were downloaded 85,000 times, placing it in the top 25% most downloaded eBooks in the relevant eBook Collection in 2016. My total research grant income as PI amounts to more than 3.2 million euros, of which 440,000 euros were secured in the last three years. In addition, I am involved as co-PI in a number of international collaborations, e.g. a NFB Life Sciences grant from NFB with Dr Oliver Langer from Austrian Institute of Technology, TÜBITAK grant with Dr Ayca Yıldız Peköz from Istanbul University and a Lung Foundation Netherlands grant with Dr Irene Heijink from the University of Groningen.

• Title

  Establishment and validation of an isolated and perfused porcine lung model for inhalation biopharmaceutical investigations
  Summary
  Funding Agency

  Enterprise Ireland
  Date From

  05/2019
  Date To

  03/2022
• Title

  Evaluation of the impact of membrane efflux transporters in the selective lung distribution of inhaled drugs
  Summary
  Funding Agency

  Enterprise Ireland
  Date From

  01/2021
  Date To

  12/2022
• Title

  PET/MR imaging to assess the role of membrane transporters in pulmonary disposition of inhaled drugs
  Summary
  Funding Agency

  Niederösterreichische Forschungs- und Bildungsgesellschaft (NFB)
  Date From

  09/2018
  Date To

  08/2021

Biochemistry and cell biology, Pharmacology and pharmaceutical sciences, Clinical Medicine,

• Travel grant from the CRS to attend the 30th Annual Meeting of the CRS, Glasgow, UK 2003
• Galenus Support Award 2012, Galenus Privatstiftung 2012
• International Research Collaboration Award, University of Sydney 2013
• Galenus Support Award 2011, Galenus Privatstiftung 2011
• Travel grant from the Nagai Foundation to attend the 28th Annual Meeting of the CRS, San Diego, CA, USA 2001
• Galenus Support Award 2008, Galenus Privatstiftung 2008
• Galenus Support Award 2009, Galenus Privatstiftung 2009
• Galenus Support Award 2010, Galenus Privatstiftung 2010
• Travel grant from the DFG to attend the Experimental Biology Meeting, Washington, DC, USA 2004
• Poster Award at the 8th German Seminar on Aerosol Therapy, Marburg, Germany 2003
• Recognition Award for Meritorious Research by a Young Investigator, American Physiological Society 2003
• Travel grant from the DPhG to attend the 6th European Congress of Pharmaceutical Sciences - EUFEPS 2000, Budapest, Hungary 2000
• "Förderung der wissenschaftlichen Nachwuchses" Fellowship from the DPhG 2002
• Fellowship, Trinity College Dublin 2013
• Galenus Support Award 2007, Galenus Privatstiftung 2007

• Deutsche Pharmazeutische Gesellschaft, DPhG Present
• Gesellschaft für Wehrmedizin und Wehrpharmazie, VdSO Present
• International Society for Aerosols in Medicine, ISAM Present
• Japanese Society for the Study of Xenobiotics, JSSX Present
• American Physiological Society, APS Present
• American Association of Pharmaceutical Scientists, AAPS Present

• Member, Board of Examiners in Pharmaceutical Technology 2002 - 2011
• Member, Editorial Board, Journal of Aerosol Medicine and Pulmonary Drug Delivery 2015 - present
• Local Co-ordinator, Marie-Curie Early Stage Training (EST) Network "Galenos EuroPhD in Advanced Drug Delivery" 2006 - 2010
• Professor Invité, Laboratoire de Pharmacie Galénique Industrielle, Faculté de Pharmacie, Université Claude Bernard Lyon 1, Lyon, France 2010 - July 2014
• Member, Editorial Board, American Journal of Physiology - Lung Cellular and Molecular Physiology 2015 - present
• Vice-Leader, WG5: Toxicity, Risk Assessment and Regulation, COST Action MP1404: Simulation and pharmaceutical technologies for advanced patient-tailored inhaled medicines (SimInhale) 2014 - 2018
• Adjunct Assistant Professor, Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA 2008 - present
• Chair, Imaging, Modeling, and Physiology of Aerosols in the Lung, International Society for Aerosols in Medicine 2013 - 2015
• Member, Management Committee, COST Action BM1201: Developmental Origins of Chronic Lung Disease 2012 - 2016
• Member, Management Committee, COST Action MP1404: Simulation and pharmaceutical technologies for advanced patient-tailored inhaled medicines (SimInhale) 2014 - 2018
• Member, Awards Committee, International Society for Aerosols in Medicine 2015 - present
• Chair, Drug Delivery: Emerging Therapies Networking Group, International Society for Aerosols in Medicine 2011 - 2013
• Member, Editorial Board, Journal of Pharmaceutical Sciences 2018 - 2020
• Member, Council, Western Epithelial Biology Society (formerly West Coast Salt and Water Club) 2015 - present
• Member, Editorial Board, European Journal of Pharmaceutics and Biopharmaceutics 2017 - present